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Found 16 Enz. Inhib. hit(s) with Target = 'Spermidine synthase'
TargetSpermidine synthase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50369035(CHEMBL608868)
Affinity DataIC50:  3nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50369035(CHEMBL608868)
Affinity DataIC50:  14nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095449(2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against spermidine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50369035(CHEMBL608868)
Affinity DataIC50:  750nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Plasmodium falciparum)
Inovacia

Curated by ChEMBL
LigandPNGBDBM50261173(4-methylcyclohexylamine | CHEMBL510738 | cis-4-met...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Plasmodium falciparum spermidine synthaseMore data for this Ligand-Target Pair
TargetSpermidine synthase(Sus scrofa)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50152094(CHEMBL3780789)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of porcine spermidine synthase assessed as production of labeled 5'-methylthioadenosine using putrescine as substrate by enzymatic assay i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095449(2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Putrescine aminopropyltransferase (PAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50404650(CHEMBL557606)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against spermidine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50404650(CHEMBL557606)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibitory activity against spermine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Plasmodium falciparum)
Inovacia

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methyl...)
Affinity DataIC50:  1.59E+5nMAssay Description:Inhibition of Plasmodium falciparum spermidine synthaseMore data for this Ligand-Target Pair
TargetSpermidine synthase(Sus scrofa)
National Institute Of Advanced Industrial Science And Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50151659(CHEMBL3775244)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of yeast ESA1 using N-terminal histone H3 substrate by radiometric filter binding based virtual screen in presence of [3H]acetyl-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50404649(CHEMBL178068)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibitory activity against spermidine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed