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Found 167 Enz. Inhib. hit(s) with Target = 'Steroid hormone receptor ERR2'
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312140(6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...)
Affinity DataKi:  0.480nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312151((E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-en...)
Affinity DataKi:  1.66nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312096(4-bromo-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquinol...)
Affinity DataKi:  3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312133(US9604931, 12z)
Affinity DataKi:  3nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312149(6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphen...)
Affinity DataKi:  3.03nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312139(2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinyl...)
Affinity DataKi:  3.96nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312134(4-bromo-6-methoxy-2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  6nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312135(6,8-dihydroxy-2-(4-hydroxyphenyl)-1-oxo-1,2-dihydr...)
Affinity DataKi:  7nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312136(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  46nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM310198(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)isoquinolin-1...)
Affinity DataKi:  49nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312137(6-hydroxy-2-(4-hydroxyphenyl)-4-phenylisoquinolin-...)
Affinity DataKi:  130nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM312138(6-hydroxy-2-(4-hydroxyphenol)-4-(4-methoxyphenyl)i...)
Affinity DataKi:  252nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233271(CHEMBL4071073)
Affinity DataIC50:  10nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233269(CHEMBL4100590)
Affinity DataIC50:  50nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485072(US10934303, Cmpd No. 27a | US10934303, Example 87)
Affinity DataIC50:  70nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM544469(87 | US11285226, Compound 27a)
Affinity DataIC50:  70nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233266(CHEMBL4092854)
Affinity DataIC50:  210nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233264(CHEMBL4085105)
Affinity DataIC50:  300nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233267(CHEMBL4084142)
Affinity DataIC50:  350nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233273(CHEMBL4064664)
Affinity DataIC50:  550nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233265(CHEMBL4065193)
Affinity DataIC50:  600nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM20608(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Affinity DataIC50:  650nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50193253(CHEMBL3961676)
Affinity DataIC50:  722nMAssay Description:Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERRbeta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233268(CHEMBL4073790)
Affinity DataIC50:  750nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50555949(CHEMBL4795846)
Affinity DataIC50:  774nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  861nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530064(CHEMBL4437929)
Affinity DataIC50:  861nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530064(CHEMBL4437929)
Affinity DataIC50:  861nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  861nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50:  886nMAssay Description:Antagonist activity at recombinant GST-tagged human ERRbeta LBD assessed as inhibition of fluorescein-labeled coactivator peptide recruitment preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530075(CHEMBL4585424)
Affinity DataIC50:  980nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485062(US10934303, Cmpd No. 20a | US10934303, Example 40 ...)
Affinity DataIC50:  980nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485062(US10934303, Cmpd No. 20a | US10934303, Example 40 ...)
Affinity DataIC50:  980nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530075(CHEMBL4585424)
Affinity DataIC50:  980nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485055(US10934303, Cmpd No. 18e | US10934303, Example 24 ...)
Affinity DataIC50:  990nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530055(CHEMBL4541589)
Affinity DataIC50:  990nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485055(US10934303, Cmpd No. 18e | US10934303, Example 24 ...)
Affinity DataIC50:  990nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530055(CHEMBL4541589)
Affinity DataIC50:  990nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530066(CHEMBL4472718)
Affinity DataIC50:  1.02E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  1.02E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM544453(25 | US11285226, Compound 18f)
Affinity DataIC50:  1.02E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530066(CHEMBL4472718)
Affinity DataIC50:  1.02E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530051(CHEMBL4580171)
Affinity DataIC50:  1.05E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485059(US10934303, Cmpd No. 18j | US10934303, Example 29 ...)
Affinity DataIC50:  1.05E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485059(US10934303, Cmpd No. 18j | US10934303, Example 29 ...)
Affinity DataIC50:  1.05E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50530051(CHEMBL4580171)
Affinity DataIC50:  1.05E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485061(US10934303, Cmpd No. 18n | US10934303, Example 33 ...)
Affinity DataIC50:  1.09E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM485061(US10934303, Cmpd No. 18n | US10934303, Example 33 ...)
Affinity DataIC50:  1.09E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50233272(CHEMBL4064246)
Affinity DataIC50:  1.10E+3nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM50555935(CHEMBL4740982)
Affinity DataIC50:  1.30E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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