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Found 20 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1-like'
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50098311(CHEMBL3590408)
Affinity DataKi:  126nMAssay Description:Binding affinity to TAF1L (unknown origin) by BROMOscan panel based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50260093(CHEMBL4078100)
Affinity DataKi:  2.51E+3nMAssay Description:Inhibition of human TAF1L bromodomain 2 expressed in bacterial expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50591066(CHEMBL5190023)
Affinity DataIC50:  124nMAssay Description:Inhibition of TAF1L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256397(CHEMBL4088466)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human TAF1L (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human TAF1L (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human TAF1L (1428 to end residues) using RRRFRPASPLRGP as substrate incubated for 120 mins in presence of [gamma33P]ATP by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of human TAF1L by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system after 1 hr by bromosc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514857(CHEMBL4449894)
Affinity DataKd:  25nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  2.50E+4nMAssay Description:Inhibition of human BRPF1 (627 to 740 residues) expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50560174(GSK789)
Affinity DataKd:  398nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50503406(CHEMBL4463538)
Affinity DataKd:  5nMAssay Description:Binding affinity to recombinant human full length DNA-tagged TAF1L bromodomain 2 (1523 to 1654 residues) expressed in bacterial expression system by ...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged TAF1L BD2 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50269687(CHEMBL4073178)
Affinity DataKd:  2.40E+6nMAssay Description:Binding affinity to human DNA-tagged TAF1L bromodomain 2 (1523 to 1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM220447(US10633379, Compound X | US9296741, 36)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human TAF1L (2) (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50148270(CHEMBL3739699)
Affinity DataKd:  3.19E+3nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-fused TAF1L bromodomain-2 (unknown origin) expressed in Escherichia coli by isothermal titrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1-like(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030894(CHEMBL3356559)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to TAF1L (unknown origin) by bromodomain displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed