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Found 3858 Enz. Inhib. hit(s) with Target = 'Serine protease 1'
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452160(CHEMBL4217569)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452156(CHEMBL4211294)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452162(CHEMBL4212172)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452158(CHEMBL1801042)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452161(CHEMBL4217607)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50452159(CHEMBL4210529)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0270nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of human cationic trypsin using Boc-VPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50069922(Boropeptide analogue | CHEMBL102069)
Affinity DataKi:  0.0450nMAssay Description:Tested for selectivity against trypsinChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50449678(CHEMBL4164510)
Affinity DataKi:  0.0460nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50034581(CHEMBL36744 | Peptide boronate)
Affinity DataKi:  0.0540nMAssay Description:Binding affinity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109663(US8609715, A-71)
Affinity DataKi:  0.0540nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50449677(CHEMBL4172393)
Affinity DataKi:  0.0620nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234238(US9346821, A-6)
Affinity DataKi:  0.0800nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520068(CHEMBL4447828)
Affinity DataKi: <0.100nMAssay Description:Inhibition of bovine beta-trypsin using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50502661(CHEMBL4531752)
Affinity DataKi: <0.100nMAssay Description:Inhibition of bovine beta-trypsin using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition and measured for 60 mins by color...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  0.100nMAssay Description:Inhibition of bovine beta-trypsin type-3 using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured over 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109651(US8609715, A-59)
Affinity DataKi:  0.120nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50034585(CHEMBL285285 | Peptide boronate)
Affinity DataKi:  0.150nMAssay Description:Binding affinity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109630(US8609715, B-21)
Affinity DataKi:  0.150nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50449679(CHEMBL4167071)
Affinity DataKi:  0.170nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109629(US8609715, B-20)
Affinity DataKi:  0.180nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109692(US8609715, B-49)
Affinity DataKi:  0.180nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109668(US8609715, B-25)
Affinity DataKi:  0.190nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234247(US9346821, B-14)
Affinity DataKi:  0.190nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109659(US8609715, A-67)
Affinity DataKi:  0.200nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109710(US8609715, C-4)
Affinity DataKi:  0.200nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234250(US9346821, B-20)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109684(US8609715, B-41)
Affinity DataKi:  0.210nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109685(US8609715, B-42)
Affinity DataKi:  0.220nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109622(US8609715, B-8)
Affinity DataKi:  0.220nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM109660(US8609715, A-68)
Affinity DataKi:  0.230nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50449680(CHEMBL4170662)
Affinity DataKi:  0.230nMAssay Description:Inhibition of bovine beta-trypsin using Boc-QAR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234266(US9346821, B-55)
Affinity DataKi:  0.240nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50088657(CHEMBL11181 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Affinity DataKi:  0.240nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234237(US9346821, A-5)
Affinity DataKi:  0.240nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM234243(US9346821, B-10)
Affinity DataKi:  0.25nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50111121(2N-(4-Benzamidinemethyl)-1-[2-Cyclohexylaminosulfo...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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