- alpha,alpha-trehalase
- alpha,alpha-trehalose glucohydrolase
- alpha-glucosidase ( alpha-glucosidase)
- alpha-glucosidase (alpha-glu)
- alpha-glucosidase (alpha-glucosidase)
- alpha-1a/alpha-1b/alpha-1d adrenergic receptor
- casein kinase ii subunit alpha/alpha 3/alpha'/beta
- integrin alpha-5/alpha-8
- integrin alpha-5/alpha-v
- integrin alpha-v/alpha-5
- voltage-dependent l-type calcium channel subunit alpha-1c/alpha-1d/alpha-1f/alpha-1s
- alpha-1a/alpha-2a adrenergic receptor
- casein kinase 1 alpha (ck1 alpha)
- hif-1-alpha, hif-2-alpha
- retinoic acid receptor rxr-alpha/alpha
- glycogen synthase kinase-3 alpha (gsk3 alpha)
- isoform alpha-4-2 of neuronal acetylcholine receptor subunit alpha-4 (alpha-4-2)
- voltage-dependent l-type calcium channel subunit alpha-1c/alpha-1d/alpha-1s
- acc-alpha
- adrenergic alpha
- alpha glucosidase
- alpha-amylase
- alpha-chymase
- alpha-chymotrypsin
- alpha-galactosidase
- alpha-galactosidase a
- alpha-glucosidase
- alpha-mannosidase
- alpha-ttp
- alpha-tubulin
- ck2- alpha
- dgk-alpha
- dgl-alpha
- ftase-alpha
- mrck alpha
- pkc alpha
- pkc-alpha
- ppar-alpha
- rar-alpha
- tap54-alpha
- thromboxane alpha
- thyroid alpha
- tnf-alpha
- casein kinase ii subunit alpha alpha beta beta
- isoform 2 of nuclear receptor ror-alpha (alpha-2)
- neuronal acetylcholine receptor subunit alpha-10/alpha-9
- retinoic acid receptor alpha/retinoid x receptor alpha
- ribosomal protein s6 kinase alpha-1/alpha-3
- alpha-2a adrenergic receptor [16-465]/alpha-2b adrenergic receptor/alpha-2c adrenergic receptor
- hypoxia inducible factors; hif-1-alpha, hif-2-alpha
- neuronal acetylcholine receptor protein alpha-10/alpha-9 subunit
- nicotinic acetylcholine receptor alpha-3/beta-4/alpha-5
- oxysterols receptor lxr-alpha/retinoic acid receptor rxr-alpha
- retinoic acid receptor rxr-alpha/thyroid hormone receptor alpha
- 20-alpha-hsd
- acidic alpha-glucosidase
- adrenergic receptor alpha
- alpha 1a-adrenoceptor
- alpha 1b-adrenoceptor
- alpha 2a adrenoceptor
- alpha carbonic anhydrase
- alpha-1-antiproteinase
- alpha-1a adrenoceptor
- alpha-2,3-sialyltransferase
- alpha-2a adrenoreceptor
- alpha-2b adrenoreceptor
- alpha-amylase 1a
- alpha-carbonic anhydrase
- alpha-elapitoxin-nk2a
- alpha-glucosidase mal12
- alpha-glucosidase mal32
- alpha-mannosidase 2
- alpha-mannosidase 2c1
- alpha-trehalose glucohydrolase
- cgk 1 alpha
- crf-r2 alpha
- deoxyribonuclease-2-alpha
- dna polymerase alpha
- estrogen receptor alpha
- gh92 alpha-mannosidase
- hpαca
- inhibin alpha chain
- meprin a subunit alpha
- n-alpha 2
- pancreatic alpha-amylase
- pgf2 alpha receptor
- pgf2-alpha receptor
- pi3k-alpha/ ephb4
- pi3k-alpha/ hck
- pi3k-alpha/ mtor
- pi3k-alpha/ src
- pi3k-alpha/ vegfr2
- pka c-alpha
- pkc alpha [mouse]
- ppar alpha/gamma
- putative alpha-glucosidase
- rac-pk-alpha
- tnf-alpha convertase
- tubulin alpha chain
- urease subunit alpha
- (1->4)-alpha-d-glucan:maltose-1-phosphate alpha-d-maltosyltransferase
- neuronal acetylcholine receptor subunit alpha-3/alpha-5/beta-4
- neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3
- neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4
- phosphatidylinositol 3-kinase 85 kda regulatory subunit alpha (pi3k alpha)
- guanine nucleotide-binding protein g(q) subunit alpha/subunit alpha-11
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (pi3k alpha)
- isoform alpha-4-2 of neuronal acetylcholine receptor subunit alpha-4 (alpha-4-2)/neuronal acetylcholine receptor subunit beta-2
- 14-alpha sterol demethylase
- 20 alpha-hydroxysteroid dehydrogenase
- 4-ph alpha-1
- acetylcholine receptor subunit alpha
- adrenergic receptor alpha-1
- adrenergic receptor alpha-2
- adrenergic receptors (alpha 2)
- alcohol dehydrogenase subunit alpha
- alpha 2b adrenergic receptor
- alpha adrenergic receptor 1a
- alpha-(1,3)-fucosyltransferase 10
- alpha-1 adrenergic receptor
- alpha-1,2-mannosidase, putative
- alpha-1a adrenergic receptor
- alpha-1b adrenergic receptor
- alpha-1c adrenergic receptor
- alpha-1d adrenergic receptor
- alpha-2 adrenergic receptor
- alpha-2a adrenergic receptor
- alpha-2b adrenergic receptor
- alpha-2c adrenergic receptor
- alpha-2d adrenergic receptor
- alpha-2da adrenergic receptor
- alpha-amylase type a isozyme
- alpha-bungarotoxin isoform a31
- alpha-crystallin a(1-172)
- alpha-fucosidase-like protein
- alpha-glucosidase (α-glucosidase)
- alpha-glucosidase a (α-gal a)
- alpha-l-fucosidase i
- alpha-l-fucoside fucohydrolase
- beta-hexosaminidase subunit alpha
- caax farnesyltransferase alpha subunit
- cam kinase i alpha
- carbonic anhydrase, alpha family
- cng channel alpha-2
- diacylglycerol kinase alpha/zeta
- dna polymerase alpha subunit
- dna topoisomerase ii alpha
- endoplasmic reticulum oxidoreductase alpha
- estrogen receptor alpha (er)
- estrogen receptor alpha d538g
- fibroblast activation protein alpha
- fibronectin receptor subunit alpha
- fucosylglycoprotein 3-alpha-galactosyltransferase
- glucan 1,4-alpha-glucosidase
- glucosidase ii subunit alpha
- golgi alpha-mannosidase ii
- gsk-3 alpha/beta
- importin subunit alpha-1
- integrin alpha 4 precursor
- integrin alpha-4/beta7
- lanosterol 14-alpha demethylase
- lanosterol 14-alpha-demethylase
- liver x receptor alpha
- lymphocyte alpha-protein kinase
- lysosomal acid alpha-mannosidase
- mannosidase 2 alpha 1
- mannosidase 2, alpha b1
- map kinase p38 alpha
- mip-1 alpha receptor
- neutral alpha-glucosidase c
- oxidoreductin-1-l-alpha
- p110-delta/ p110-alpha
- pancreatic eif2-alpha kinase
- peptidylglycine alpha-amidating monooxygenase
- peptidylglycine alpha-hydroxylating monooxygenase
- pi3k-alpha/ dna-pk
- pi3k-alpha/ p110-gamma
- pka catalytic subunit alpha
- pkc alpha and beta-2
- plasma alpha-l-fucosidase
- pld alpha c2 domain
- probable alpha-glucosidase os06g0675700
- prostaglandin f2-alpha receptor
- protein kinase c, alpha
- protein-tyrosine phosphatase alpha
- retinoic acid receptor alpha
- retinoid x receptor alpha
- rna polymerase subunit alpha
- sodium channel alpha subunit
- steroid 17-alpha-monooxygenase
- steroid 5-alpha-reductase
- sterol 14-alpha demethylase
- tissue alpha-l-fucosidase
- tnf-alpha-converting enzyme
- tropomyosin alpha-1 chain
- tubulin alpha-1a chain
- tubulin alpha-1c chain
- vla-4 subunit alpha
- isoform alpha-1 of mitogen-activated protein kinase 10 (alpha-1) 9-402]
- neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3
- n-type calcium channel subunits alpha 1b (cav2.2), beta 3, and alpha 2 delta
- 1,4-alpha-d-glucan glucanohydrolase
- 1,4-alpha-d-glucan glucohydrolase
- 20-alpha-hydroxysteroid dehydrogenase (akr1c1)
- 25-ohd-1 alpha-hydroxylase
- acetylcholine receptor protein alpha chain
- alpha adrenergic receptor (1a and 1d)
- alpha adrenergic receptor 1a and 1b
- alpha adrenergic receptor 1a and 1d
- alpha-enolase/huntingtin [1-89]
- beta-hexosaminidase subunit alpha (hexa)
- beta-hexosaminidase subunit alpha/beta
- cam kinase ii alpha/beta
- casein kinase i isoform alpha
- casein kinase ii alpha (prime)
- casein kinase ii alpha''''/ beta
- casein kinase ii alpha/beta
- casein kinase ii subunit alpha
- cerebral cortex alpha adrenergic receptor
- cholinergic receptor, nicotinic alpha 1
- collagen alpha-1(ii) chain
- diacylglycerol kinase alpha [9-727]
- dna polymerase (alpha/delta/epsilon)
- dna polymerase alpha catalytic subunit
- dna polymerase iii subunit alpha
- exo-1,5-alpha-l-arabinofuranobiosidase
- g-protein subunit alpha-16
- gaba receptor alpha-1 subunit
- gaba receptor alpha-2 subunit
- gaba receptor alpha-3 subunit
- gaba receptor alpha-5 subunit
- gaba receptor alpha-6 subunit
- gaba(a) receptor subunit alpha-1
- gaba-a receptor subunit alpha 1
- galnac alpha-2,6-sialyltransferase iii
- gdnf family receptor alpha-like
- glycine receptor (alpha-1/beta)
- glycine receptor alpha-2 chain
- glycine receptor alpha-3/beta
- glycine receptor alpha-4 chain
- glycine receptor subunit alpha-1
- glycine receptor subunit alpha-2
- glycine receptor subunit alpha-3
- histamine h2-gs alpha s
- ige fc receptor, alpha-subunit
- integrin alpha m/beta-2
- integrin alpha-1/beta-1
- integrin alpha-2/beta-3
- integrin alpha-3/beta-3
- integrin alpha-4/beta-1
- integrin alpha-4/beta-7
- integrin alpha-5/beta-1
- integrin alpha-5/beta-6
- integrin alpha-5/beta-8
- integrin alpha-iib/beta-3
- integrin alpha-v light chain
- integrin alpha-v/beta-3
- integrin alpha-v/beta-5
- interleukin-2 receptor alpha chain
- interleukin-5 receptor subunit alpha
- interleukin-6 receptor alpha chain
- liver x receptor alpha (lxra)
- maltase-glucoamylase (alpha-glucosidase) pseudogene
- n-acetyllactosaminide alpha-1,3-galactosyltransferase
- p38 map kinase alpha/beta
- p450 sterol 14-alpha-demethylase
- peroxisome proliferator activated receptor alpha
- peroxisome proliferator-activated receptor alpha
- pge receptor, ep3 isoform alpha
- phosphatidylinositol 4-kinase alpha (pi4ka)
- phosphoinositide 3-kinase (pi3k), alpha
- pi3-kinase p110-alpha subunit
- pi3k-alpha/ src mutant (t338i)
- proteasome subunit alpha type-6
- protein kinase c alpha type
- retinoic acid receptor rxr-alpha
- retinoic acid receptors gamma / alpha
- similar to alpha-tubulin isoform 1
- sterol 14-alpha demethylase (cyp51)
- sterol 14-alpha demethylase cyp51a
- tryptophan synthase alpha /beta chains
- tubulin alpha chain /beta chain
- tubulin alpha chain-like 2
- tubulin alpha-1a/beta chain
- urease subunit alpha/beta/gamma
- phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [e545k]
- phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [h1047r]
- voltage-dependent l-type calcium channel subunit beta-1/alpha-1b/alpha-2/delta-1
- actin, alpha skeletal muscle, intermediate form
- adenylate kinase 3 alpha like 1
- alpha-2a adrenergic receptor [16-465]
- alpha-carbonic anhydrase domain-containing protein
- amiloride-sensitive sodium channel subunit alpha
- casein kinase i isoform alpha-like
- casein kinase i isoform alpha/delta
- casein kinase ii subunit alpha (csnk2a2)
- casein kinase ii subunit alpha/beta
- cholinergic receptor nicotinic alpha 5 subunit
- cholinergic receptor nicotinic alpha 6 subunit
- dna topoisomerase 2-alpha/2-beta
- estrogen-related receptor, alpha mutant (c325s)
- fibronectin receptor beta/vitronectin receptor alpha
- gaba(a) receptor subunit alpha-5 (gabaaa5)
- gaba-a receptor alpha-1/beta-3
- geranylgeranyl transferase type ii subunit alpha
- glucocorticoid receptor isoform alpha variant 1
- glycine receptor subunit alpha-2/beta
- glycogen synthase kinase-3 alpha/beta
- heat shock protein hsp 90-alpha
- hydrolase, alpha/beta hydrolase fold family
- integrin alpha-10/integrin beta-1
- integrin alpha-2/beta-1 [t112h]
- integrin beta-3/vitronectin receptor alpha
- integrin subunit alpha 2b/beta-3
- macrophage inflammatory protein-1 alpha receptor
- mannosidase alpha class 2b member 2
- map kinase p38 alpha mutant (g110a)
- map kinase p38 alpha mutant (g110d)
- mitogen-activated protein kinase p38 alpha
- neuronal acetylcholine receptor subunit alpha-2
- neuronal acetylcholine receptor subunit alpha-3
- neuronal acetylcholine receptor subunit alpha-4
- neuronal acetylcholine receptor subunit alpha-5
- neuronal acetylcholine receptor subunit alpha-6
- neuronal acetylcholine receptor subunit alpha-7
- neuronal acetylcholine receptor subunit alpha-9
- oxysterols receptor lxr-alpha [197-447]
- oxysterols receptor lxr-alpha/lxr-beta
- phenylalanine--trna ligase alpha/beta subunit
- phosphatidylinositol 4-kinase type 2-alpha
- phosphoinositide-3-kinase catalytic alpha polypeptide
- pi3-kinase p110-delta/p85-alpha
- platelet-derived growth factor alpha polypeptide
- platelet-derived growth factor receptor alpha
- prolyl 4-hydroxylase alpha-1 subunit
- protein farnesyltransferase alpha subunit/subunit beta
- putative glycogen synthase kinase 3 alpha
- retinoic acid receptor alpha [200-419]
- retinoic acid receptor rxr-alpha/gamma
- retinoic acid receptor, alpha, isoform cra_b
- retinoid x receptor alpha (f313i/l436f)
- solube guanylate cyclase alpha-1 (sgcalpha)
- thyroid hormone receptor alpha [148-410]
- urease subunit alpha [f36l]/beta/gamma
- urease subunit alpha/urease subunit beta
CHEMBL1084541 BDBM50318914 (+/-)-alpha-tocopherol nicotinate
Alpha Tocopherol BDBM50458513 Aquasol E E307 Vitamin E CHEBI:18145 Tocopherol
alpha,alpha'-dipyridyl 2-(2-pyridyl)pyridine bpy alpha,alpha'-bipyridyl 2,2'-Bipyridin 2,2'-bipyridyl US10196346, Bipyridine 2,2'-dipyridine 2,2'-bipyridine alpha,alpha'-bipyridine alpha,alpha'-dipyridine BDBM50042874 CHEMBL39879 2,2'-dipyridyl
(-)-ALPHA-BISABOLOL BDBM50382730 ALPHA-BISABOLOL
US9259470, Alpha US8697715, Alpha BDBM120126
(1S)-1-phenylethanamine BDBM50028638 L-(-)-alpha-phenylethylamine L(-)-alpha-methylbenzylamine (S)-alpha-methylbenzenemethanamine (alphaS)-alpha-methylbenzenemethanamine CHEMBL282700 (S)-(-)-alpha-methylbenzylamine L-alpha-methylbenzylamine L-(-)-1-phenylethylamine (-)-alpha-phenethylamine
Alpha, alpha-dimethyl derivative, 5 BDBM82120
2-alpha-11-alpha-dihydroxyfawcettidine BDBM50213090 CHEMBL376327
Alpha-Tocopheryl Succinate (+)-ALPHA-TOCOPHERYL SUCCINATE BDBM50458511
(R)-alpha-methoxy-alpha-trifluoromethyl phenylacetic acid BDBM36091
ALPHA-MSH CAS_10466-28-1 alpha MSH BDBM82412
BDBM36092 (S)-alpha-methoxy-alpha-trifluoromethyl phenylacetic acid
CHEMBL1398 Alpha-Phenyl-Gamma-Butyrolactone BDBM50180937 alpha-phenylbutyrolactone
CHEMBL216458 alpha-bungarotoxin BDBM50121739 Bungarotoxin Neuronal Bungarotoxin,Alpha
TMPNPNPthymidine 5'-[alpha,beta:beta,alpha-diimido]triphosphate BDBM50002467
CHEMBL486197 BDBM50241894 gorgostane-3-beta,9-alpha,5-alpha,6-beta,11-alpha-tetrol
D-alpha-methylbenzylamine BDBM50028628 CHEMBL19969 (R)-alpha-methylbenzenemethanamine (alphaR)-alpha-methylbenzenemethanamine (1R)-1-phenylethanamine
1-phenylethanamine 1-phenylethylamine CHEMBL278059 alpha-Methylbenzylamine BDBM50023171 alpha-Phenylethylamine 1-amino-1-phenylethane 1-phenethylamine alpha-methylbenzenemethanamine alpha-aminoethylbenzene
BDBM50014945 alpha-methyl-5-hydroxytryptamine CHEMBL275854 alpha-methyl-5-HT alpha-methylserotonin 3-(2-aminopropyl)-1H-indol-5-ol alpha-M-5-HT
Alpha-ureidophosphonate, a BDBM86793
BDBM50378887 ALPHA-CONIDENDRIN
BDBM50470946 Alpha-Hydroxytrimethoprim
BDBM93095 Alpha-Phenylguanidine
alpha-ddCHA BDBM82067
Alpha-Methylhistane-R CHEMBL268229 R-alpha-methylhistamine (2R)-1-(1H-imidazol-5-yl)propan-2-amine Alpha-Methylhistamine-R RAMH BDBM22904 (R)-alpha-Methylhistamine
methyl phenidylacetate BDBM50062912 methyl alpha-phenyl-alpha-(2-piperidyl)acetate alpha-phenyl-2-piperidineacetic acid methyl ester methyl phenyl(piperidin-2-yl)acetate methylphenidan methyl alpha-phenyl-alpha-2-piperidinylacetate CHEMBL796 Methylphenidate
(R)-(-)-ALPHA-METHYLHISTAMINE DIHYDROBROMIDE Alpha-Methylhistamine-R CAS_75614-87-8 BDBM81973
alpha-oxobutyrate 2-oxobutanate 2-oxobutanoate BDBM50273975 2-ketobutyrate alpha-ketobutyrate
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide CHEMBL517 DISOPYRAMIDE gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide BDBM50028893 alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide
ALPHA-HYDRAZINE ORNITHINE BDBM50487428
Alpha-Tocopherylquinone BDBM50041386 CHEMBL1223852
Alpha-ureidophosphonate, d BDBM86795
Alpha-ureidophosphonate, e BDBM86796
Alpha-ureidophosphonate, g BDBM86797
Alpha-ureidophosphonate, k BDBM86799
BDBM22903 N(alpha)-Methylhistamine
BDBM50194425 CHEMBL218788 alpha-cyclocostunolide
BDBM50252405 Pifithrin-Alpha CHEMBL556353
BDBM50305202 CHEMBL589873 alpha-Methylcinnamaldoxime
BDBM50531261 alpha-amyrenone CHEMBL518475
BDBM82406 desacetyl-alpha-MSH
BDBM85022 alpha-MSH, [Nle4]
BDBM85837 h alpha-CGRP
BDBM86794 Alpha-ureidophosphonate, b
BDBM86798 Alpha-ureidophosphonate, i
CHEMBL1289337 alpha-rhamnoisorobin BDBM50331857
CHEMBL198759 BDBM50478353 Pifithrin-Alpha
CHEMBL520915 alpha-methylcubebin BDBM50259857
alpha-Phenylbutyrolactone CHEMBL380124 BDBM50180939
alpha-benzoyloxypaeoniflorin BDBM50310714 CHEMBL1079225
3 ALPHA-HYDROXY-7 ALPHA-FLUORO-5 BETA-CHOLAN-24-OIC A BDBM50375555
BDBM50156923 CHEMBL221993 (1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carboxylic acid
BDBM50177106 2-beta-3-beta-diphenyltropane CHEMBL388850 2-alpha-3-alpha-diphenyltropane
BDBM50208825 (+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-7 alpha,9'-lactone CHEMBL227135
CHEMBL374712 BDBM50156921 (1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carboxylic acid
CHEMBL571174 BDBM50301393 1-[4-(4-methylcyclohexyl)butyl]alpha,alpha-diphenyl-4-piperdinemethanol
alpha,alpha-Dimethylphenethylamine 2-methyl-1-phenylpropan-2-amine CHEMBL1574 BDBM50246598 PHENTERMINE
(2R)-amino(phenyl)acetic acid D-alpha-phenylglycine D-(-)-alpha-Phenylglycine BDBM50179720 CHEMBL1403
17-cyclopropylmethyl-3,14-beta-dihydroxy-4,5-alpha-epoxy-6-alpha-(benzamido)morphinan BDBM86942
BDBM50301391 1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4-piperdine-methanol CHEMBL571389
uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen diphosphate] UDP-alpha-D-glucose BDBM50209659
CHEMBL578629 BDBM50300442 (20R)-4,5-alpha-Epoxy-17-methyl-3-hydroxy-6-methoxy-alpha-17-dimethyl-alpha-(2-phenylethyl)-6,14-ethenomorphinan-7-methanol
(R)-alpha-methoxyphenylacetic acid BDBM36089
(S)-alpha-methoxyphenylacetic acid BDBM36090
7 alpha-Spirobenzocyclohexylhydromorphone CHEMBL318361 BDBM50059992
7 alpha-Spirobenzocyclohexyloxymorphone BDBM50059990 CHEMBL318598
BDBM220119 US9271961, alpha-Mehtylcinnamic acid
BDBM36009 L-alpha-o-benzylglycerol
BDBM50059994 CHEMBL105081 7 alpha-Spirobenzocyclohexylnaltrexone
BDBM50288610 Alpha-ketocarbonyl derivative CHEMBL98937
BDBM50472559 (S)-Alpha-Methylhistamine CHEMBL11919
BDBM641071 US20230399418, Compound alpha-Methylfentanyl
BDBM85130 14-alpha-triptolide, 7
BDBM86517 5-(GSyl)-alpha-MethylDopamine
CHEMBL1084610 Hydroxy-alpha-sanshool BDBM50318477
CHEMBL1170424 BDBM50322610 alpha-Sulfanylbenzylphosphonic acid
CHEMBL1172388 alpha-Sulfanylpropylphosphonic acid BDBM50322608
CHEMBL317337 Alpha-ketocarbonyl derivative BDBM50288609
CHEMBL439569 1-alpha-mesyloxysalvinorin A BDBM50223620
[Pro14]h alpha-CGRP BDBM85834
alpha-ketoamide inhibitor 13a BDBM420293
CHEMBL425373 BDBM50168310 [ alpha-Neu5Ac-(2,3)-beta-D-Gal-(1,4) (alpha-Fuc-(1,3))-D-Glc ]
N-alpha-methylhistamine N-methylhistamine BDBM22530 [3H]N-alpha-methyl histamine NAMH N(alpha)-Methylhistamine [2-(1H-imidazol-5-yl)ethyl](methyl)amine
N-alpha-Ac-[Trp30]PYY(22-36)-NH2 CHEMBL412698 N-alpha-Ac-[D-Trp30]PYY(22-36)-NH2(N-alpha-Ac-ASLAHYLNWVTRQRY-NH2) BDBM50091674
Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester OXYBUTYNIN CHLORIDE 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat CHEMBL1231 BDBM50165019 Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
(R)-3beta-(methylphenyl)-2-beta-phenyltropane (R)-3-alpha-(methylphenyl)-2-alpha-phenyltropane CHEMBL224771 BDBM50177109
BDBM50091661 N-alpha-Ac-[Trp28]PYY(22-36)-NH2(N-alpha-Ac-ASLAHYWNLVTRQRY-NH2) CHEMBL410938
BDBM50091687 N-alpha-Ac-[Tic27]PYY(22-36)-NH2(N-alpha-Ac-ASLAHTicLNLVTRQRY-NH2) CHEMBL263350
CAS_75614-93-6 Alpha-Methylhistamine-S (S)-(+)-ALPHA-METHYL-1H-IMIDAZOLE-4-ETHANAMINE DIHYDROBROMIDE BDBM81972
CHEMBL410792 N-alpha-Ac-[Nal30]PYY(22-36)-NH2(N-alpha-Ac-ASLAHYLNNalVTRQRY-NH2) BDBM50091662
CHEMBL413612 N-alpha-Ac-[Phe27]PYY(22-36)-NH2(N-alpha-Ac-ASLAHFLNLVTRQRY-NH2) BDBM50091666
CHEMBL428320 BDBM50091670 N-alpha-Ac-[Trp27]PYY(22-36)-NH2(N-alpha-Ac-ASLAHWLNLVTRQRY-NH2)
CHEMBL429905 N-alpha-Ac-[Phe27,36]PYY(22-36)-NH2(N-alpha-Ac-ASLAHFLNLVTRQRF-NH2) BDBM50091676
CHEMBL438935 BDBM50091673 N-alpha-Ac-[Trp29]PYY(22-36)-NH2(N-alpha-Ac-ASLAHYLWLVTRQRY-NH2)
N-alpha-Ac-[Nal27]PYY(22-36)-NH2(N-alpha-Ac-ASLAHNalLNLVTRQRY-NH2) BDBM50091660 CHEMBL429698
N-alpha-Ac-[Phe22,27]PYY(22-36)-NH2(N-alpha-Ac-FSLAHFLNLVTRQRY-NH2) CHEMBL405527 BDBM50091677
N-alpha-Ac-[Trp24]PYY(22-36)-NH2(N-alpha-Ac-ASWAHYLNLVTRQRY-NH2) CHEMBL438096 BDBM50091683
N-alpha-Ac-[Trp28,30]PYY(22-36)-NH2(N-alpha-Ac-ASLAHYWNWVTRQRY-NH2) CHEMBL411637 BDBM50091685
alpha-homonojirimycin (alpha-HNJ) (2R,3R,5S,6R)-2,6-bis(hydroxymethyl)piperidine-3,4,5-triol BDBM18366
alpha-toluenesulfonyl fluoride Benzenemethanesulfonyl fluoride BDBM50171289 PMSF CHEMBL190503 phenylmethylsulfonyl fluoride Phenylmethanesulfonyl fluoride alpha-toluenesulphonyl fluoride
kaempferol-3,7-O-(alpha)-dirhamnoside kaempferol-3,7-O-alpha-L-dirhamnoside BDBM50331856 Karempferitrin CHEMBL251766 kaempferitrin
BDBM50027502 alpha-Methyl-(-)norepinephrine,(+/-) CHEMBL764 METHYLNORADRENALINE Aldoclor-150 4-(2-Amino-1-hydroxy-propyl)-benzene-1,2-diol alpha-Methyl-(+)norepinephrine,(+/-) Aldoclor-250 alpha-Methyl-(+/-)norepinephrine,(+/-)
afzelin kaempferol 3-O-alpha-L-rhamnopyranoside kaempferol-3-O-alpha-L-rhamnoside kaempferol 3-O-rhamnoside CHEMBL240528 BDBM50213414 kaempferol-3-O-alpha-L-rhamnopyranoside
ALPHA-ERGOCRYPTINE SMR000058703 BDBM50855 cid_6852403 MLS000069839
Aethylbenzol BDBM50167951 ethylbenzene CHEMBL371561 alpha-methyltoluene
BDBM30134 alpha-sulfone piperidine hydroxamate, 11a
BDBM30135 alpha-sulfone piperidine hydroxamate, 1a
BDBM30137 alpha-sulfone piperidine hydroxamate, 11b
BDBM30138 alpha-sulfone piperidine hydroxamate, 11c
BDBM30139 alpha-sulfone piperidine hydroxamate, 1b
BDBM30143 alpha-sulfone piperidine hydroxamate, 1c
BDBM30145 alpha-sulfone piperidine hydroxamate, 11f
BDBM30146 alpha-sulfone piperidine hydroxamate, 11g
BDBM30147 alpha-sulfone piperidine hydroxamate, 1d
BDBM33409 alpha, gamma-diketo acid, 1
BDBM435730 US10610539, Compound alpha-L-rhamnose
BDBM435733 US10610539, Compound alpha-D-rhamnose
BDBM50007907 CHEMBL3350647 alpha,beta-methylene AzddTPP
BDBM50166886 CHEMBL195368 methyl alpha-D-mannoside
BDBM50254511 Naltrexone-6-alpha-ol CHEMBL468469
BDBM85021 alpha-MSH, [Nle4, D-Phe7]
BDBM85719 PGF2 Alpha, 1-isopropyl ester
BDBM85838 [Cha37]h alpha-CGRP8-37
BDBM86193 Alpha-Helical CRF CAS_0 NSC_0
BDBM9938 depeptidized alpha-ketoamide inhibitor 34
CHEMBL1771738 (rac)-alpha-methylbenzyl fumarate BDBM50342419
CHEMBL383808 alpha-methylnaphthalene 1-methylnaphthalene BDBM50159279
D-aspartate alpha-benzyl ester BDBM92988
Dihydro-alpha-ergocryptine NSC_159729 BDBM81453 CAS_159729
SMR000127418 BDBM89803 MLS000517299 ALPHA-SOLANINE cid_9549171
US10512644, Compound alpha-6-Hydrocodonol BDBM425923
US10610539, Compound alpha-D-amicetose BDBM435727
US10610539, Compound alpha-L-amicetose BDBM435724
[Ala37]h alpha-CGRP8-37 BDBM85842
[D-Pen2,7]h alpha-CGRP BDBM85843
alpha-sulfone piperidine hydroxamate, 11d BDBM30141
alpha-sulfone piperidine hydroxamate, 11e BDBM30142
alpha-sulfone piperidine hydroxamate, 11h BDBM30148
alpha-sulfone piperidine hydroxamate, 11i BDBM30149
alpha-sulfone piperidine hydroxamate, 11j BDBM30150
alpha-sulfone piperidine hydroxamate, 11k BDBM30151
alpha-sulfone piperidine hydroxamate, 11l BDBM30152
alpha-sulfone piperidine hydroxamate, 11m BDBM30154
alpha-sulfone piperidine hydroxamate, 11n BDBM30155
alpha-sulfone piperidine hydroxamate, 1e BDBM30153
BDBM50091653 CHEMBL266021 N-alpha-Ac-[Nle24,28,30,Nva31]PYY(22-36)-NH2(N-alpha-Ac-ASNleAHYNleNNleNvaTRQRY-NH2)
CHEMBL298510 Boc-Phe-His-Sta-Leu-(-)-alpha-naphthylthylamide Boc-Phe-His-Sta-Leu-(+)-alpha-naphthylthylamide BDBM50023095
CHEMBL427594 BDBM50091658 N-alpha-Ac-[Tyr22,Phe27]PYY(22-36)-NH2(N-alpha-Ac-YSLAHFLNLVTRQRY-NH2)
N-alpha-Ac-[Ala26,Phe27]PYY(22-36)-NH2(N-alpha-Ac-ASLAAFLNLVTRQRY-NH2) CHEMBL425095 BDBM50091671
BDBM50135912 NILUTAMIDE 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione CHEMBL1274 5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
BDBM50307386 Dodecyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->2)-3,4,6-tri-O-sulfo-alpha-D-mannopyranoside, Hexadecasodium Salt CHEMBL604367
CHEMBL235708 BDBM50221269 4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[alpha,alpha-diphenyl methylene]semicarbazide
N-alpha-Ac-PYY(22-36)-NH2(N-alpha-Ac-ASLAHYLNLVTRQRY-NH2) BDBM50091668 AcPYY(22-36) CHEMBL269267
N-alpha-Ac-[Nle24,28,Trp30,Nva31]PYY(22-36)-NH2(N-alpha-Ac-ASNleAHYNleNWNvaTRQRY-NH2) CHEMBL411200 BDBM50091651
N-alpha-Ac-[Trp27]PYY(22-36)-NH2-CH3(N-alpha-Ac-ASLAHWLNLVTRQRY-NH-CH3) CHEMBL415644 BDBM50091686
Benzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->2)-3,4,6-tri-O-sulfo-alpha-D-mannopyranoside, TridecasodiumSalt CHEMBL589773 BDBM50307399
Octyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->2)-3,4,6-tri-O-sulfo-alpha-D-mannopyranoside, TridecasodiumSalt CHEMBL602113 BDBM50307401
N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 6 CHEMBL308495 N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 5 N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 4 BDBM50137675 4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-benzenesulfonamide
4-Butylbenzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->3)-2,4,6-tri-O-sulfo-alpha-D-mannopyranosyl-(1->2)-3,4,6-tri-O-sulfo-alpha-D-mannopyranoside, TridecasodiumSalt CHEMBL590010 BDBM50307402
3-O-acetyl-alpha-mangostin CHEMBL1782242 BDBM50346336
Alpha-Cobratoxin COBRATOXIN BDBM82544 CAS_69344-74-7
Alpha-Neoendorphin CB0427223 BDBM82083 CAS_69671-17-6
BDBM248155 Cathepsin S inhibitor alpha-ketoamide, 6a
BDBM248156 Cathepsin S inhibitor alpha-ketoamide, 6b
BDBM248157 Cathepsin S inhibitor alpha-ketoamide, 6e
BDBM248160 Cathepsin S inhibitor alpha-ketoamide, 6r
BDBM248161 Cathepsin S inhibitor alpha-ketoamide, 6w
BDBM50002468 TMPNPPthymidine 5'-[alpha,beta-imido]triphosphate
BDBM50176938 alpha-methylalanyl-L-proline butylamide CHEMBL388062
BDBM50242272 6-O-alpha-rhamnopyranosyl-DMJ CHEMBL469655
BDBM50346341 6-O-benzoyl-alpha-mangostin CHEMBL1782245
CHEMBL1347 BDBM50404648 3-O-Methyl-Alpha-Methyldopamine
CHEMBL268229 CHEBI:73337 (R)-Alpha-Methylhistamine BDBM50215536
Cathepsin S inhibitor alpha-ketoamide, 6n BDBM248158
Cathepsin S inhibitor alpha-ketoamide, 6p BDBM248159
N-alpha-FMOC-L-tryptophan CHEMBL152301 BDBM50121967
afzelechin-3-O-alpha-Lrhamnopyranoside CHEMBL517149 BDBM50269600
alpha-borano-2-Mes-ATP CHEMBL601711 BDBM50308333
alpha-cyclodextrin doubly bridged dimer, 6 BDBM36277
ddTMPNPPDideoxythymidine 5'-[alpha,beta-imido]triphosphate BDBM50002469
quercetin 3-O-alpha-L-rhamnopyranoside BDBM50241358
- López, GV; Gómez, LE; Campillo, N; Páez, JA; Giles, K; Atkinson, J; González, M; Rubbo, H; Cerecetto, H Interaction studies between human alpha-tocopherol transfer protein and nitric oxide donor tocopherol analogues with LDL-protective activity. Bioorg Med Chem 17: 8143-8 (2009)
- Yan, R; Chuang, HC; Kapuriya, N; Chou, CC; Lai, PT; Chang, HW; Yang, CN; Kulp, SK; Chen, CS Exploitation of the ability of¿-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors. J Med Chem 58: 2290-8 (2015)
- Uhlén, S; Porter, AC; Neubig, RR The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors. J Pharmacol Exp Ther 271: 1558-65 (1994)
- Han, W; Hu, Z; Jiang, X; Decicco, CP Alpha-ketoamides, alpha-ketoesters and alpha-diketones as HCV NS3 protease inhibitors. Bioorg Med Chem Lett 10: 711-3 (2000)
- Hadingham, KL; Wingrove, P; Le Bourdelles, B; Palmer, KJ; Ragan, CI; Whiting, PJ Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors. Mol Pharmacol 43: 970-5 (1993)
- García-Echeverría, C; Gay, B; Rahuel, J; Furet, P Mapping the X(+1) binding site of the Grb2-SH2 domain with alpha,alpha-disubstituted cyclic alpha-amino acids. Bioorg Med Chem Lett 9: 2915-20 (1999)
- Li, Z; Patil, GS; Golubski, ZE; Hori, H; Tehrani, K; Foreman, JE; Eveleth, DD; Bartus, RT; Powers, JC Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases. J Med Chem 36: 3472-80 (1993)
- Wang, Q; Huang, Z; Ramachandran, C; Dinaut, AN; Taylor, SD Naphthalenebis[alpha,alpha-difluoromethylenephosphonates] as potent inhibitors of protein tyrosine phosphatases. Bioorg Med Chem Lett 8: 345-50 (1999)
- Thaisrivongs, S; Schostarez, HJ; Pals, DT; Turner, SR alpha,alpha-Difluoro-beta-aminodeoxystatine-containing renin inhibitory peptides. J Med Chem 30: 1837-42 (1987)
- Tu, Z; Kotzbauer, PT; Yue, X; Dhavale, DD Alpha-synuclein ligands US Patent US12012394 (2024)
- Fagan, GP; Chapleo, CB; Lane, AC; Myers, M; Roach, AG; Smith, CF; Stillings, MR; Welbourn, AP Indoline analogues of idazoxan: potent alpha 2-antagonists and alpha 1-agonists. J Med Chem 31: 944-8 (1988)
- Campbell, DA; Xiao, XY; Harris, D; Ida, S; Mortezaei, R; Ngu, K; Shi, L; Tien, D; Wang, Y; Navre, M; Patel, DV; Sharr, MA; DiJoseph, JF; Killar, LM; Leone, CL; Levin, JI; Skotnicki, JS Malonyl alpha-mercaptoketones and alpha-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors. Bioorg Med Chem Lett 8: 1157-62 (1999)
- Xu, Y; Rito, CJ; Etgen, GJ; Ardecky, RJ; Bean, JS; Bensch, WR; Bosley, JR; Broderick, CL; Brooks, DA; Dominianni, SJ; Hahn, PJ; Liu, S; Mais, DE; Montrose-Rafizadeh, C; Ogilvie, KM; Oldham, BA; Peters, M; Rungta, DK; Shuker, AJ; Stephenson, GA; Tripp, AE; Wilson, SB; Winneroski, LL; Zink, R; Kauffman, RF; McCarthy, JR Design and synthesis of alpha-aryloxy-alpha-methylhydrocinnamic acids: a novel class of dual peroxisome proliferator-activated receptor alpha/gamma agonists. J Med Chem 47: 2422-5 (2004)
- Horikawa, M; Shigeri, Y; Yumoto, N; Yoshikawa, S; Nakajima, T; Ohfune, Y Syntheses of potent Leu-enkephalin analogs possessing beta-hydroxy-alpha,alpha-disubstituted-alpha-amino acid and their characterization to opioid receptors. Bioorg Med Chem Lett 8: 2027-32 (1999)
- Megens, AA; Leysen, JE; Awouters, FH; Niemegeers, CJ Further validation of in vivo and in vitro pharmacological procedures for assessing the alpha 2/alpha 1-selectivity of test compounds: (1). Alpha-adrenoceptor antagonists. Eur J Pharmacol 129: 49-55 (1986)
- Letourneau, JJ; Liu, J; Ohlmeyer, MH; Riviello, C; Rong, Y; Li, H; Appell, KC; Bansal, S; Jacob, B; Wong, A; Webb, ML Synthesis and initial evaluation of novel, non-peptidic antagonists of the alpha(v)-integrins alpha(v)beta(3) and alpha(v)beta(5). Bioorg Med Chem Lett 19: 352-5 (2008)
- DeMarinis, RM; Bryan, WM; Shah, DH; Hieble, JP; Pendleton, RG Alpha-adrenergic agents. 1. Direct-acting alpha 1 agonists related to methoxamine. J Med Chem 24: 1432-7 (1982)
- Peng, FC Structure and anti-acetylcholinesterase activity of 4 alpha-(hydroxymethyl)-4 alpha-demethylterritrem B. J Nat Prod 60: 842-3 (1997)
- Sisto, A; Altamura, M; Cardinali, F; D'Andrea, P; Rossi, C; Fattori, D alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists. Bioorg Med Chem Lett 17: 4841-4 (2007)
- Bey, P; Gerhart, F; Van Dorsselaer, V; Danzin, C alpha-(Fluoromethyl)dehydroornithine and alpha-(fluoromethyl)dehydroputrescine analogues as irreversible inhibitors of ornithine decarboxylase. J Med Chem 26: 1551-6 (1983)
- Gambacorti-Passerini, C; Mologni, L; Scapozza, L; Bisson, W; Ahmed, S; Goekjian, P; Tardy, S; Orsato, A; Gueyrard, D; Benoit, J Alpha-carbolines for the treatment of cancer US Patent US9428500 (2016)
- GIROUX, S; CLARK, MP; TANG, Q; NUHANT, PM; JONES, P; MESSERSMITH, D; BANDARAGE, UK; COTTRELL, KM; BRODNEY, MA; FLEMING, GS; WANG, J; XU, J; DANIEL, KB; BOYD, MJ; MORRIS, MA; WAAL, ND; COLLIER, PN; KESAVAN, S; RONKIN, SM; DENG, H; BOUCHER, DM; FANNING, LT; HALL, AB; HURLEY, DJ; JOHNSON, Jr., MA; MAXWELL, JP; SWETT, RJ; TAPLEY, TL; THOMSON, SA; DAMAGNEZ, V MODULATORS OF ALPHA-1 ANTITRYPSIN US Patent US20230339915 (2023)
- Taylor, CA; Smith, HE; Goldberg, MR; Robertson, D (alpha S)-erythro-alpha-methylepinephrine: preparation and stereoselective binding to adrenergic receptors in rat forebrain. J Med Chem 24: 1261-3 (1981)
- Ao, G; Nie, J; Li, H; Mo, L; Chen, L; Song, H; Chen, S Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof US Patent US9409845 (2016)
- Timmermans, PB; de Jonge, A; Thoolen, MJ; Wilffert, B; Batink, H; van Zwieten, PA Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. J Med Chem 27: 495-503 (1984)
- Lin, LS; Lanza, T; McCauley, E; Van Riper, G; Kidambi, U; Cao, J; Egger, LA; Mumford, RA; Schmidt, JA; MacCoss, M; Hagmann, WK Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins. Bioorg Med Chem Lett 12: 133-6 (2001)
- Lee, HK; Lee, YS; Roh, EJ; Rhim, H; Lee, JY; Shin, KJ Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers. Bioorg Med Chem Lett 18: 4424-7 (2008)
- Laughlin, SK; Clark, MP; Djung, JF; Golebiowski, A; Brugel, TA; Sabat, M; Bookland, RG; Laufersweiler, MJ; VanRens, JC; Townes, JA; De, B; Hsieh, LC; Xu, SC; Walter, RL; Mekel, MJ; Janusz, MJ The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production. Bioorg Med Chem Lett 15: 2399-403 (2005)
- Clark, RD; Repke, DB; Kilpatrick, AT; Brown, CM; MacKinnon, AC; Clague, RU; Spedding, M (8a alpha,12a alpha,13a alpha)-5,8,8a,9,10,11,12,12a,13,13a-decahydro- 3-methoxy-12-(methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridi ne, a potent and highly selective alpha 2-adrenoceptor antagonist. J Med Chem 32: 2034-6 (1989)
- Korstanje, C; Sprenkels, R; Doods, HN; Hugtenburg, JG; Boddeke, E; Batink, HD; Thoolen, MJ; Van Zwieten, PA Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol 38: 374-9 (1986)
- Miyachi, H; Uchiki, H Analysis of the critical structural determinant(s) of species-selective peroxisome proliferator-activated receptor alpha (PPAR alpha)-activation by phenylpropanoic acid-type PPAR alpha agonists. Bioorg Med Chem Lett 13: 3145-9 (2003)
- Gomeza, J; Mary, S; Brabet, I; Parmentier, ML; Restituito, S; Bockaert, J; Pin, JP Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists. Mol Pharmacol 50: 923-30 (1996)
- Welbourn, AP; Chapleo, CB; Lane, AC; Myers, PL; Roach, AG; Smith, CF; Stillings, MR; Tulloch, IF Alpha-adrenoreceptor reagents. 4. Resolution of some potent selective prejunctional alpha 2-adrenoreceptor antagonists. J Med Chem 29: 2000-3 (1986)
- Harvey, AJ; Abell, AD Alpha-ketoester-based photobiological switches: synthesis, peptide chain extension and assay against alpha-chymotrypsin. Bioorg Med Chem Lett 11: 2441-4 (2001)
- Skiles, JW; Miao, C; Sorcek, R; Jacober, S; Mui, PW; Chow, G; Weldon, SM; Possanza, G; Skoog, M; Keirns, J Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1. J Med Chem 35: 4795-808 (1993)
- Becker, DP; DeCrescenzo, G; Freskos, J; Getman, DP; Hockerman, SL; Li, M; Mehta, P; Munie, GE; Swearingen, C alpha-Alkyl-alpha-amino-beta-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1. Bioorg Med Chem Lett 11: 2723-5 (2001)
- Boger, DL; Miyauchi, H; Hedrick, MP alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. Bioorg Med Chem Lett 11: 1517-20 (2001)
- Duggan, ME; Duong, LT; Fisher, JE; Hamill, TG; Hoffman, WF; Huff, JR; Ihle, NC; Leu, CT; Nagy, RM; Perkins, JJ; Rodan, SB; Wesolowski, G; Whitman, DB; Zartman, AE; Rodan, GA; Hartman, GD Nonpeptide alpha(v)beta(3) antagonists. 1. Transformation of a potent, integrin-selective alpha(IIb)beta(3) antagonist into a potent alpha(v)beta(3) antagonist. J Med Chem 43: 3736-45 (2000)
- Carling, RW; Moore, KW; Street, LJ; Wild, D; Isted, C; Leeson, PD; Thomas, S; O'Connor, D; McKernan, RM; Quirk, K; Cook, SM; Atack, JR; Wafford, KA; Thompson, SA; Dawson, GR; Ferris, P; Castro, JL 3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1. J Med Chem 47: 1807-22 (2004)
- Sheppard, D; DeGrado, WF; Jo, H; Sundaram, A; Beresis, R Alpha-5 beta-1 inhibitors US Patent US11530180 (2022)
- Zetterberg, F; Nilsson, U; Leffler, H Alpha-D-galactoside inhibitors of galectins US Patent US10889610 (2021)
- St Maurice, M; Bearne, SL; Lu, W; Taylor, SD Inhibition of mandelate racemase by alpha-fluorobenzylphosphonates. Bioorg Med Chem Lett 13: 2041-4 (2003)
- Bilcer, GM; Ng, R Quinuclidines for modulating alpha 7 activity US Patent US9434724 (2016)
- BOLLLI, M; GATFIELD, J; GRISOSTOMI, C; REMEN, L; SAGER, C; ZUMBRUNN, C SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES US Patent US20230295182 (2023)
- Ocain, TD; Rich, DH alpha-Keto amide inhibitors of aminopeptidases. J Med Chem 35: 451-6 (1992)
- Quik, M; Choremis, J; Komourian, J; Lukas, RJ; Puchacz, E Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites. J Neurochem 67: 145-54 (1996)
- Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype. J Med Chem 47: 6160-73 (2004)
- Scholze, P; Ebert, V; Sieghart, W Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits. Eur J Pharmacol 304: 155-62 (1996)
- Poirier, D; Boivin, RP 17 alpha-alkyl- or 17 alpha-substituted benzyl-17 beta-estradiols: a new family of estrone-sulfatase inhibitors. Bioorg Med Chem Lett 8: 1891-6 (1999)
- Dyatkin, AB; Hoekstra, WJ; Kinney, WA; Kontoyianni, M; Santulli, RJ; Kimball, ES; Fisher, MC; Carolyn Fisher, M; Prouty, SM; Abraham, WM; de Garavilla, L; Andrade-Gordon, P; Hlasta, DJ; He, W; Hornby, PJ; Damiano, BP; Maryanoff, BE Aza-bicyclic amino acid sulfonamides as alpha(4)beta(1)/alpha(4)beta(7) integrin antagonists. Bioorg Med Chem Lett 14: 591-6 (2004)
- Wang, Y; Guan, L; Jia, S; Tseng, B; Drewe, J; Cai, SX Dipeptidyl aspartyl fluoromethylketones as potent caspase inhibitors: peptidomimetic replacement of the P2 alpha-amino acid by a alpha-hydroxy acid. Bioorg Med Chem Lett 15: 1379-83 (2005)
- Edwards, PD; Zottola, MA; Davis, M; Williams, J; Tuthill, PA Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl alpha-ketobenzoxazoles. J Med Chem 38: 3972-82 (1995)
- Yokomatsu, T; Murano, T; Umesue, I; Soeda, S; Shimeno, H; Shibuya, S Synthesis and biological evaluation of alpha,alpha-difluorobenzylphosphonic acid derivatives as small molecular inhibitors of protein-tyrosine phosphatase 1B. Bioorg Med Chem Lett 9: 529-32 (1999)
- Jiang, S; Chang, AC; Abraham, P; Kuhar, MJ; Carroll, FI Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes. Bioorg Med Chem Lett 8: 3689-92 (1999)
- Barbaro, R; Betti, L; Botta, M; Corelli, F; Giannaccini, G; Maccari, L; Manetti, F; Strappaghetti, G; Corsano, S Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors. J Med Chem 44: 2118-32 (2001)
- Bishop, MJ; Barvian, KA; Berman, J; Bigham, EC; Garrison, DT; Gobel, MJ; Hodson, SJ; Irving, PE; Liacos, JA; Navas, F; Saussy, DL; Speake, JD alpha(1)-Adrenoceptor agonists: the identification of novel alpha(1A )subtype selective 2'-heteroaryl-2-(phenoxymethyl)imidazolines. Bioorg Med Chem Lett 12: 471-5 (2002)
- Araujo, F; Ruano, D; Vitorica, J Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties. J Pharmacol Exp Ther 290: 989-97 (1999)
- Gao, H; Kawabata, J 2-Aminoresorcinol is a potent alpha-glucosidase inhibitor. Bioorg Med Chem Lett 18: 812-5 (2008)
- Blough, BE; Landavazo, A; Partilla, JS; Decker, AM; Page, KM; Baumann, MH; Rothman, RB Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett 24: 4754-8 (2014)
- Wada, CK; Frey, RR; Ji, Z; Curtin, ML; Garland, RB; Holms, JH; Li, J; Pease, LJ; Guo, J; Glaser, KB; Marcotte, PA; Richardson, PL; Murphy, SS; Bouska, JJ; Tapang, P; Magoc, TJ; Albert, DH; Davidsen, SK; Michaelides, MR Alpha-keto amides as inhibitors of histone deacetylase. Bioorg Med Chem Lett 13: 3331-5 (2003)
- Wash, PL; Hoffman, TZ; Wiley, BM; Bonnefous, C; Smith, ND; Sertic, MS; Lawrence, CM; Symons, KT; Nguyen, PM; Lustig, KD; Guo, X; Annable, T; Noble, SA; Hager, JH; Hassig, CA; Malecha, JW Alpha-mercaptoketone based histone deacetylase inhibitors. Bioorg Med Chem Lett 18: 6482-5 (2008)
- Sou, S; Mayumi, S; Takahashi, H; Yamasaki, R; Kadoya, S; Sodeoka, M; Hashimoto, Y Novel alpha-glucosidase inhibitors with a tetrachlorophthalimide skeleton. Bioorg Med Chem Lett 10: 1081-4 (2000)
- Petersen, A; Benz, J; Grether, U; Hornsperger, B; Kocer, B; Kuhn, B; Richter, H; Tsuchiya, S; Qiu, Y; Chen, R Octahydropyrido[1,2-alpha]pyrazines as MAGL inhibitors US Patent US11608347 (2023)
- Li, MY; Tsai, KC; Xia, L Pharmacophore identification of alpha(1A)-adrenoceptor antagonists. Bioorg Med Chem Lett 15: 657-64 (2005)
- Turner, M; Eidemiller, S; Martin, B; Narver, A; Marshall, J; Zemp, L; Cornell, KA; McIntosh, JM; McDougal, OM Structural basis for alpha-conotoxin potency and selectivity. Bioorg Med Chem 17: 5894-9 (2009)
- Huff, JR; Baldwin, JJ; deSolms, SJ; Guare, JP; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors. J Med Chem 31: 641-5 (1988)
- Zhang, N; Tomizawa, M; Casida, JE 5-Azidoepibatidine: an exceptionally potent photoaffinity ligand for neuronal alpha 4 beta 2 and alpha 7 nicotinic acetylcholine receptors. Bioorg Med Chem Lett 13: 525-7 (2003)
- Angelastro, MR; Mehdi, S; Burkhart, JP; Peet, NP; Bey, P Alpha-diketone and alpha-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases. J Med Chem 33: 11-3 (1990)
- DeBernardis, JF; Kyncl, JJ; Basha, FZ; Arendsen, DL; Martin, YC; Winn, M; Kerkman, DJ Conformationally defined adrenergic agents. 2. Catechol imidazoline derivatives: biological effects at alpha 1 and alpha 2 adrenergic receptors. J Med Chem 29: 463-7 (1986)
- Minarini, A; Budriesi, R; Chiarini, A; Leonardi, A; Melchiorre, C Search for alpha 1-adrenoceptor subtypes selective antagonists: design, synthesis and biological activity of cystazosin, an alpha 1D-adrenoceptor antagonist. Bioorg Med Chem Lett 8: 1353-8 (1999)
- Chang, LL; Truong, Q; Mumford, RA; Egger, LA; Kidambi, U; Lyons, K; McCauley, E; Van Riper, G; Vincent, S; Schmidt, JA; MacCoss, M; Hagmann, WK The discovery of small molecule carbamates as potent dual alpha(4)beta(1)/alpha(4)beta(7) integrin antagonists. Bioorg Med Chem Lett 12: 159-63 (2001)
- Chapleo, CB; Myers, PL; Butler, RC; Doxey, JC; Roach, AG; Smith, CF alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants. J Med Chem 26: 823-31 (1983)
- Grinevich, VP; Letchworth, SR; Lindenberger, KA; Menager, J; Mary, V; Sadieva, KA; Buhlman, LM; Bohme, GA; Pradier, L; Benavides, J; Lukas, RJ; Bencherif, M Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit. J Pharmacol Exp Ther 312: 619-26 (2005)
- Bishop, MJ; Berman, J; Bigham, EC; Garrison, DT; Gobel, MJ; Hodson, SJ; Irving, PE; Liacos, JA; Minick, DJ; Navas, F; Saussy, DL; Speake, JD 2-(Anilinomethyl)imidazolines as alpha(1)-adrenoceptor agonists: the identification of alpha(1A) subtype selective 2'-carboxylic acid esters and amides. Bioorg Med Chem Lett 11: 2871-4 (2001)
- Kline, RH; Izenwasser, S; Katz, JL; Joseph, DB; Bowen, WD; Newman, AH 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile. J Med Chem 40: 851-7 (1997)
- Alpegiani, M; Bissolino, P; Corigli, R; Del Nero, S; Perrone, E; Rizzo, V; Sacchi, N; Cassinelli, G; Franceschi, G; Baici, A Cephem sulfones as inactivators of human leukocyte elastase. 5. 7 alpha-Methoxy- and 7 alpha-chloro-1,1-dioxocephem 4-ketones. J Med Chem 37: 4003-19 (1994)
- Potter, GA; Barrie, SE; Jarman, M; Rowlands, MG Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer. J Med Chem 38: 2463-71 (1995)
- Mayorov, AV; Cai, M; Palmer, ES; Dedek, MM; Cain, JP; Van Scoy, AR; Tan, B; Vagner, J; Trivedi, D; Hruby, VJ Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor. J Med Chem 51: 187-95 (2008)
- Ogawa, S; Watanabe, M; Maruyama, A; Hisamatsu, S Synthesis of an alpha-fucosidase inhibitor, 5a-carba-beta-L-fucopyranosylamine, and fucose-type alpha- and beta-DL-valienamine unsaturated derivatives. Bioorg Med Chem Lett 12: 749-52 (2002)
- Yoshida, K; Horikoshi, Y; Eta, M; Chikazawa, J; Ogishima, M; Fukuda, Y; Sato, H Synthesis of benzanilide derivatives as dual acting agents with alpha 1-adrenoceptor antagonistic action and steroid 5-alpha reductase inhibitory activity. Bioorg Med Chem Lett 8: 2967-72 (1998)