Query String: APOMORPHINE
BDBM50367948 Apokyn APOMORPHINE HYDROCHLORIDE Apomorphine
6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride (R)-(-)-Apomorphine hydrochloride BDBM50012986 Apokyn APOMORPHINE HYDROCHLORIDE Apomorphine CHEMBL1616
CAS_314-19-2 NSC_2215 APOMORPHINE BDBM86896
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride APOMORPHINE HYDROCHLORIDE HEMIHYDRATE BDBM29644 US20240166639, Example Apomorphine SMR000059235 MLS000069811 APOMORPHINE HYDROCHLORIDE cid_6852399
(R)-(-)-2-Methyl-apomorphine hydrochloride CHEMBL507567 CHEMBL557547 BDBM50251028
BDBM50251026 CHEMBL465054 (R)-(-)-2-Phenyl-apomorphine hydrochloride CHEMBL458397
1,2-Bis-[R-(-)-apomorphine-2'-oxy]ethane BDBM50251330 CHEMBL442926
2-{[R-(-)-Apomorphine-2'-oxy]ethoxy}-ethanol BDBM50251329 CHEMBL516151
BDBM50251027 CHEMBL517028 (R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochloride CHEMBL458579
CHEMBL444149 Bis-{[R-(-)-apomorphine-2-oxy]ethyl} ether BDBM50251331
CHEMBL465696 BDBM50251034 (R)-(-)-2-(4-dibenzo-furanyl)-apomorphine hydrochloride
CHEMBL458587 (R)-(-)-2-(4-N,N-Dimethylaminophenyl)-apomorphine dihydrochloride BDBM50251029
[R-(-)-Apomorphine-2-yl]-(2'-hydroxy-ethyl)ether CHEMBL457275 BDBM50251328
(-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO) (Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine) (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine) BDBM50001955 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol APOKYN APOMORPHINE 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) APOMORPHINE HYDROCHLORIDE (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine) CHEMBL53
CHEMBL416288 (S)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(Apomorphine) (S)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol BDBM50010691 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
CHEMBL416288 MLS000028867 BDBM29643 S(+)-10,11-DIHYDROXYAPORPHINE HYDROCHLORIDE Apomorphine,(+) (6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride cid_6852389 US10864248, Compound 1 SMR000058671 (S)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
- Ishiba, H; Noguchi, T; Shu, K; Ohno, H; Honda, K; Kondoh, Y; Osada, H; Fujii, N; Oishi, S Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction. Bioorg Med Chem Lett 27: 2571-2574 (2017)
- Schneider, CS; Mierau, J Dopamine autoreceptor agonists: resolution and pharmacological activity of 2,6-diaminotetrahydrobenzothiazole and an aminothiazole analogue of apomorphine. J Med Chem 30: 494-8 (1987)
- Nordmann, R; Petcher, TJ Octahydrobenzo[g]quinolines: potent dopamine agonists which show the relationship between ergolines and apomorphine. J Med Chem 28: 367-75 (1985)
- Park, H; Urs, AN; Zimmerman, J; Liu, C; Wang, Q; Urs, NM Structure-Functional-Selectivity Relationship Studies of Novel Apomorphine Analogs to Develop D1R/D2R Biased Ligands. ACS Med Chem Lett 11: 385-392 (2020)
- ChEMBL_1724720 (CHEMBL4139998) Displacement of [3H]apomorphine from rat caudate dopamine receptor
- ChEMBL_177222 (CHEMBL783697) Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum
- ChEMBL_216107 (CHEMBL816030) Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum
- ChEMBL_216108 (CHEMBL816031) Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum
- ChEMBL_43124 (CHEMBL884268) Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)
- ChEMBL_216106 (CHEMBL816029) Tested for affinity against dopamine autoreceptor using [3H]apomorphine in rat brain
- ChEMBL_60009 (CHEMBL675834) In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes
- ChEMBL_60026 (CHEMBL672122) Tested for displacement of rat caudate dopamine receptors by using [3H]apomorphine as radioligand
- ChEMBL_60028 (CHEMBL672124) Tested for displacement of rat striatal dopamine receptors by using [3H]apomorphine as radioligand
- ChEMBL_60161 (CHEMBL675708) Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudate
- ChEBML_61602 Inhibitory activity against Dopamine receptor D2 in rat corpus striatum using [3H]Apomorphine as radioligand
- ChEMBL_59599 (CHEMBL672156) Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.
- ChEMBL_1760146 (CHEMBL4195154) Antagonist activity at human D2 receptor expressed in CHO-K1 cells co-expressing Galphaqi5 assessed as decrease in apomorphine-induced calcium mobilization preincubated for 30 mins followed by apomorphine challenge measured for 30 secs by aequorin-derived luminescence assay
- ChEMBL_61602 (CHEMBL675925) Inhibitory activity against Dopamine receptor D2 in rat corpus striatum using [3H]Apomorphine as radioligand
- ChEMBL_59876 (CHEMBL673002) Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranes
- ChEBML_60234 In vitro ability to inhibit the binding of [3H]spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss mice
- ChEBML_60694 In vitro ability to inhibit the binding of [3H]spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss mice
- ChEMBL_58522 (CHEMBL672017) Binding affinity measured at the Dopamine receptor D1 by the inhibition of [3H]SCH-23390 binding to rat striatum using unlabeled apomorphine for nonspecific binding.
- ChEMBL_60234 (CHEMBL671416) In vitro ability to inhibit the binding of [3H]spiperone to cloned human Dopamine receptor D2 using apomorphine induced climbing test in male Swiss mice
- ChEMBL_60694 (CHEMBL676504) In vitro ability to inhibit the binding of [3H]spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss mice
- ChEBML_62293 In vitro ability to inhibit the binding of [3H]7-OH-DPAT to cloned human Dopamine receptor D3 using apomorphine induced climbing test in male Swiss mice
- ChEMBL_1468605 (CHEMBL3413551) Antagonist activity at human dopamine D2 receptor expressed in CHOK1 cells assessed as inhibition of apomorphine-induced calcium mobilization by radiometric and luminescence plate counting method
- ChEMBL_1468781 (CHEMBL3414320) Antagonist activity against human recombinant dopmaine D2L receptor expressed in CHOK1 cells assessed as reduction in apomorphine-induced increase in intracellular Ca2+ levels by aequorin based radiometric and luminescence plate counting method