BDBM50063995 Bedaquiline TMC207 CHEBI:72292
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- Tong, AST; Choi, PJ; Blaser, A; Sutherland, HS; Tsang, SKY; Guillemont, J; Motte, M; Cooper, CB; Andries, K; Van den Broeck, W; Franzblau, SG; Upton, AM; Denny, WA; Palmer, BD; Conole, D 6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis. ACS Med Chem Lett 8: 1019-1024 (2017)
- Blaser, A; Sutherland, HS; Tong, AST; Choi, PJ; Conole, D; Franzblau, SG; Cooper, CB; Upton, AM; Lotlikar, M; Denny, WA; Palmer, BD Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline. Bioorg Med Chem 27: 1283-1291 (2019)
- Barbaro, L; Nagalingam, G; Triccas, JA; Tan, L; West, NP; Baell, JB; Priebbenow, DL Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit. RSC Med Chem 12: 943-959 (2021)
- Sutherland, HS; Tong, AST; Choi, PJ; Blaser, A; Conole, D; Franzblau, SG; Lotlikar, MU; Cooper, CB; Upton, AM; Denny, WA; Palmer, BD 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel. Bioorg Med Chem 27: 1292-1307 (2019)
- Choi, PJ; Sutherland, HS; Tong, AST; Blaser, A; Franzblau, SG; Cooper, CB; Lotlikar, MU; Upton, AM; Guillemont, J; Motte, M; Queguiner, L; Andries, K; Van den Broeck, W; Denny, WA; Palmer, BD Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units. Bioorg Med Chem Lett 27: 5190-5196 (2017)
- Sutherland, HS; Tong, AST; Choi, PJ; Conole, D; Blaser, A; Franzblau, SG; Cooper, CB; Upton, AM; Lotlikar, MU; Denny, WA; Palmer, BD Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles. Bioorg Med Chem 26: 1797-1809 (2018)