Simple Search Results

Query String: CERITINIB

LDK378 US10618884, Example 16 CERITINIB CHEMBL2403108 US10053458, Comparative Example 2 US9809572, Example 16 BDBM50436850

Mathi, GR; Kang, CH; Lee, HK; Achary, R; Lee, HY; Lee, JY; Ha, JD; Ahn, S; Park, CH; Lee, CO; Hwang, JY; Yun, CS; Jung, HJ; Cho, SY; Kim, HR; Kim, P Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R. Eur J Med Chem 126: 536-549 (2017)

ChEMBL_1880814 Inhibition of EGFR in human DFCI032 cells assessed as reduction in cell viability after 72 hrs in presence of ceritinib by MTS assay
ChEMBL_1880818 Inhibition of EGFR in human DFCI076 cells assessed as reduction in cell viability after 72 hrs by MTS assay in presence of ceritinib