Query String: CLONIDINE
N-(2,6-dichlorophenyl)imidazolidin-2-imine BDBM14062 Clonidine [3H]clonidine
ST-155 BDBM50020341 Catapres Clonidine HCl Kapvay Jenloga CLONIDINE HYDROCHLORIDE Dichloranilino Imidazolin Duraclon
CLONIDINE N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine BDBM50016897 2-(2,6-dichloroanilino)-2-imidazoline 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) clonidine (amino form)
Catapres-Tts-2 Catapres-Tts-3 Combipres Catapres Catapres-Tts-1 ST-155BS ST-155-BS CHEBI:3757 BDBM50225285 Clorpres Clonidine Duraclon
- Chapleo, CB; Butler, RC; England, DC; Myers, PL; Roach, AG; Smith, CF; Stillings, MR; Tulloch, IF Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine. J Med Chem 32: 1627-30 (1989)
- Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine. J Pharmacol Exp Ther 295: 1192-205 (2000)
- ChEMBL_32524 Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptor
- ChEMBL_58169 Affinity for displacement of [3H]clonidine labeled Dopamine receptor D1
- ChEMBL_604280 Displacement of [3H]Clonidine from human adrenergic alpha2A receptor
- ChEMBL_604281 Displacement of [3H]Clonidine from human adrenergic alpha2B receptor
- ChEMBL_1343083 Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brain
- ChEMBL_216306 Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brain
- ChEMBL_220571 Displacement of [3H]-clonidine from bovine imidazoline receptor I-1
- ChEMBL_33791 Ability to bind at alpha-2 adrenergic receptor by displacing [3H]clonidine
- ChEMBL_34225 Binding affinity to alpha-2 adrenergic receptor by displacement of [3H]clonidine
- ChEMBL_604282 Displacement of [3H]Clonidine from human adrenergic Alpha-2C receptor
- ChEMBL_1365251 Displacement of [3H]clonidine from human adrenergic-alpha2A receptor by PDSP assay
- ChEMBL_1365252 Displacement of [3H]clonidine from human adrenergic-alpha2C receptor by PDSP assay
- ChEMBL_33792 Displacement of [3H]clonidine from alpha-2 adrenergic receptor in rat brain
- ChEMBL_33909 Binding affinity against the alpha-2 adrenergic receptor using [3H]- clonidine
- ChEBML_217144 The binding affinity was measured on alpha-2-adrenergic receptor using [3H]- clonidine as radioligand.
- ChEMBL_217143 Tested for affinity against alpha-2-adrenergic using [3H]clonidine in rat brain
- ChEMBL_217144 The binding affinity was measured on alpha-2-adrenergic receptor using [3H]- clonidine as radioligand.
- ChEMBL_32316 Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat brain membranes
- ChEMBL_32629 Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat cortex membrane
- ChEMBL_32752 Displacement of [3H]clonidine from rat cortex membrane Alpha-2 adrenergic receptors
- ChEMBL_32760 Displacement of [3H]-clonidine from Alpha-2 adrenergic receptor of rat cortex membranes
- ChEMBL_514514 Displacement of [3H]clonidine from Imidazoline receptor 1 rat PC-12 cells
- ChEMBL_552879 Displacement of [3H]clonidine from imidazoline 1 receptor in Sprague-Dawley rat kidney
- ChEMBL_797759 Displacement of [3H]clonidine from human Alpha-2C receptor by liquid scintillation counting
- ChEMBL_164464 Inhibition of specific [3H]-clonidine binding (0.4 nM) to rat brain membranes alpha2 adrenoceptor
- ChEMBL_164468 Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes alpha2 adrenoceptor
- ChEMBL_164469 Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes alpha2 adrenoceptor
- ChEMBL_217147 Compound was tested for its ability to inhibit specific binding of [3H]-clonidine to alpha-2-adrenoceptor.
- ChEMBL_30085 Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes
- ChEMBL_30242 In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortex
- ChEMBL_302984 In vitro binding affinity against rat Alpha-2 adrenergic receptor using [3H]clonidine
- ChEMBL_329331 Displacement of [3H]clonidine from cloned human adrenergic alpha2A receptor expressed in Sf9 cells
- ChEMBL_33213 Inhibitory concentration required against Alpha-2A adrenergic receptor using [3H]clonidine radioligand
- ChEMBL_33214 Inhibitory concentration required against Alpha-2A adrenergic receptor using [3H]clonidine radioligand
- ChEMBL_33516 Inhibitory concentration required against Alpha-2A adrenergic receptor using [3H]clonidine radioligand
- ChEMBL_33517 Inhibitory concentration required against Alpha-2C adrenergic receptor using [3H]clonidine radioligand
- ChEMBL_33773 Compound was evaluated for binding activity against [3H]clonidine as radioligand for alpha-2 adrenergic receptor
- ChEMBL_33907 Binding affinity against alpha-2 adrenergic receptor in rat brain using [3H]- clonidine
- ChEMBL_33927 Binding affinity against alpha-2 adrenergic receptor in rat brain using [3H]- clonidine
- ChEMBL_34058 Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex
- ChEMBL_34063 Inhibitory concentration required against Alpha-2 adrenergic receptor in rat cortex [3H]clonidine
- ChEMBL_514509 Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney membrane
- ChEMBL_88904 Displacement of [3H]clonidine from imidazoline receptor I-1 of bovine chromaffin cell membranes
- ChEBML_33030 Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranes
- ChEBML_33032 Binding affinity at Alpha-2 adrenergic receptor in calf cerebral cortex homogenates by [3H]clonidine displacement.
- ChEBML_34062 Inhibitory concentration against radioligand [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex
- ChEMBL_2050317 Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay
- ChEMBL_216139 Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro
- ChEMBL_216309 In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidine
- ChEMBL_218082 Binding affinity against alpha-2-adrenoceptor was determined by displacement of [3H]-clonidine in rat brain homogenates
- ChEMBL_32315 The ability to displace [3H]clonidine from the Alpha-2 adrenergic receptor was determined in rat brain membrane
- ChEMBL_329332 Displacement of [3H]clonidine from cloned human adrenergic Alpha-2C receptor expressed in Sf9 cells
- ChEMBL_33030 Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranes
- ChEMBL_33043 Binding affinity towards Alpha-2 adrenergic receptor of calf brain cortex using [3H]clonidine
- ChEMBL_34065 The compound was evaluated for the alpha-2 adrenergic receptor antagonistic activity in rat vas deferens vs clonidine
- ChEMBL_34076 Ability to displace [3H]-clonidine from alpha-1 adrenergic receptor in rat brain homogenates in vitro
- ChEMBL_34077 Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitro
- ChEMBL_519677 Displacement of [3H]clonidine from imidazoline I1 receptor in Wistar rat kidney by liquid scintillation counting
- ChEMBL_884849 Displacement of [3H]clonidine from alpha2C adrenergic receptor after 40 mins by scintillation counting analysis
- ChEMBL_884850 Displacement of [3H]clonidine from alpha2A adrenergic receptor after 40 mins by scintillation counting analysis
- ChEMBL_935397 Displacement of [3H]clonidine from alpha2-adrenergic receptor in rat cerebral cortex by liquid scintillation counting
- ChEBML_33039 Displacement of [3H]- clonidine radioligand binding at the alpha-2 adrenergic receptor binding site of calf cerebral cortex
- ChEBML_33040 Evaluated for its ability to displace [3H]clonidine from alpha-2 adrenergic receptor of calf cerebral cortex
- ChEMBL_1760118 Displacement of [3H]clonidine from rat cerebral cortex adrenergic receptor alpha2 by liquid scintillation counting method
- ChEMBL_216305 Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brain
- ChEMBL_216440 In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidine
- ChEMBL_217146 Compound was tested for its ability to inhibit specific binding of [3H]clonidine to alpha-2-adrenoceptor in rat brain
- ChEMBL_32934 In vitro presynaptic agonist potency at alpha-2 adrenergic receptor in rat or mouse vas deferens relative to clonidine
- ChEMBL_33836 Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparation
- ChEMBL_33908 Binding affinity against alpha-2 adrenergic receptor was measured using radioligand ([3H]clonidine) binding assay
- ChEMBL_34052 Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes Alpha-2 adrenergic receptor
- ChEMBL_34053 Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes alpha-2 adrenergic receptor
- ChEMBL_34378 Alpha-2 adrenergic receptor binding affinity by measuring the displacement of [3H]clonidine binding in rat cerebral cortex
- ChEMBL_34493 Compound was tested for the inhibition of [3H]clonidine binding Alpha-2 adrenergic receptor of crude rat brain membrane
- ChEMBL_519674 Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation counting
- ChEBML_220578 Inhibition of 3 nM [3H]clonidine binding to rat kidney membrane imidazoline receptor I-1 in presence of rauwolscine
- ChEBML_33027 Concentration necessary to achieve half maximal inhibition of [3H]clonidine binding to Alpha-2 adrenergic receptor at 1 uM
- ChEBML_33031 Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligand
- ChEMBL_30105 Binding affinity against alpha 2-Adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]clonidine
- ChEMBL_30106 Binding affinity against alpha 2-Adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]clonidine
- ChEMBL_30107 Binding affinity against alpha-2 adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]clonidine
- ChEMBL_33027 Concentration necessary to achieve half maximal inhibition of [3H]clonidine binding to Alpha-2 adrenergic receptor at 1 uM
- ChEMBL_33033 Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligand
- ChEMBL_33183 Binding affinity against alpha 2-Adrenergic receptor in guinea pig cerebral cortical membranes by displacement of [3H]clonidine
- ChEMBL_34046 Compound was tested for its ability to inhibit specific binding of [3H]clonidine to alpha-2 adrenergic receptor in rat brain
- ChEMBL_34231 Binding affinity towards alpha-2 adrenergic receptor from rat brain homogenate preparation by displacement of [3H]clonidine
- ChEMBL_34511 In vitro binding affinity was measured as the inhibition of [3H]clonidine binding to alpha-2 adrenergic receptor of rat cortical membranes
- ChEMBL_34518 Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H] clonidine as radioligand in rat brain cortex
- ChEMBL_34519 Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H]- clonidine as radioligand in rat brain cortex.
- ChEMBL_34520 In vitro binding affinity determined for alpha-2 adrenergic receptor by the percentage displacement of [3H]- clonidine at 10e-6 M
- ChEMBL_591271 Displacement of [3H]Clonidine from alpha2 adrenergic receptor in Wistar rat cerebral cortex membrane by liquid scintillation counting
- alpha-Adrenoceptor Radioligand Binding Assay The binding affinity of compound was evaluated using [3H] Clonidine as ligand in competition binding experiments. Nonspecific binding was determined as the concentration of ligand bound in the presence of 2 uM phentolamine. Ki values were determined by the equation: Ki = IC50/(1 + [clonidine]/KD).
- ChEMBL_1527273 Displacement of [3H]-Clonidine from recombinant human adrenergic alpha2B receptor after 1.5 hrs by Microbeta scintillation counting analysis
- ChEMBL_1527274 Displacement of [3H]-Clonidine from recombinant human adrenergic alpha2C receptor after 1.5 hrs by Microbeta scintillation counting analysis
- ChEMBL_1527395 Displacement of [3H]-Clonidine from recombinant human adrenergic alpha2A receptor after 1.5 hrs by Microbeta scintillation counting analysis
- ChEMBL_164470 Inhibition of specific [3H]-clonidine binding (0.4 nM) to rat brain membranes alpha-2 adrenoceptor; 2.8*10e-7
- ChEMBL_218547 Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes
- ChEMBL_32398 Compound was tested for its binding affinity for alpha-1 adrenoceptor site by displacement of [3H]-clonidine at 10e-6 M concentration
- ChEMBL_33035 Binding affinity against alpha-2 adrenergic receptor was determined in calf cerebral cortex homogenates using [3H]clonidine as radioligand
- ChEMBL_33901 Ability to inhibit 50% specific binding of [3H]-p-amino clonidine radioligand to alpha-2 adrenergic receptor in rat cerebrocortex
- ChEMBL_33912 50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranes
- ChEMBL_34050 In vitro inhibitory activity was evaluated against,[3H]clonidine (Clon) rat brain minus cerebellum Alpha-2 adrenergic receptor
- ChEMBL_34208 Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes
- ChEMBL_34506 In vitro binding affinity towards alpha-2 adrenergic receptor in rat frontal cortex homogenate using of [3H]clonidine as radioligand
- ChEMBL_1732885 Displacement of [3H]-clonidine from alpha2-adrenergic receptor in rat brain cortex after 30 mins by Microbeta scintillation counting method
- ChEMBL_1858223 Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectrometry
- ChEMBL_32395 Compound was tested for its binding affinity for alpha-1 adrenergic receptor site by displacement of [3H]clonidine at 10e-6 M concentration
- ChEMBL_32396 Compound was tested for its binding affinity for alpha-1 adrenergic receptor site by displacement of [3H]clonidine at 10e-6 M concentration
- ChEMBL_32397 Compound was tested for its binding affinity for alpha-1 adrenergic receptor site by displacement of [3H]clonidine at 10e-6 M concentration
- ChEMBL_33926 Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranes
- ChEMBL_34049 In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligand
- ChEMBL_34207 Binding affinity against alpha-2 adrenergic receptor by measuring displacement of [3H]clonidine from rat brain cortex membranes (in vitro).
- ChEMBL_34211 Binding affinity for alpha-2 adrenergic receptor by displacement of [3H]clonidine at 10e-6 M from rat brain homogenate preparation
- ChEMBL_34381 Compound was tested for its binding affinity for alpha-2 adrenergic receptor site by displacement of [3H]clonidine at 10e-6 M concentration
- ChEMBL_793655 Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by scintillation counting
- ChEMBL_32766 Binding affinity measured at the Alpha-2 adrenergic receptor by the inhibition of [3H]clonidine binding to rat cortex using unlabeled NAbitartrate for nonspecific binding.
- ChEMBL_33184 Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.
- ChEMBL_33185 Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.
- ChEMBL_698561 Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney membrane after 45 mins by liquid scintillation counting
- ChEMBL_1576288 Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting
- ChEMBL_33904 Alpha-2 adrenergic receptor blocking activity by antagonism of clonidine induced depression of twitch response of field stimulated prostatic portion of rat vas deferens
- ChEMBL_34379 Alpha-2 adrenergic receptor binding affinity by measuring the displacement of [3H]clonidine binding in rat cerebral cortex; Not Active means Ki >1000 nM
- ChEMBL_33924 Binding affinity against alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported.
- ChEMBL_33913 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]-clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 1*10e-6
- ChEMBL_33914 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 1.4*10e-7
- ChEMBL_33915 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 1.6*10e-8
- ChEMBL_33916 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 2.3*10e-8
- ChEMBL_33917 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 2.5*10e-8
- ChEMBL_33918 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 2.5*10e-9
- ChEMBL_33919 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 3.0*10e-8
- ChEMBL_33920 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 3.6*10e-9
- ChEMBL_33921 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 4.8*10e-9
- ChEMBL_33922 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]-clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 5.9*10e-8
- ChEMBL_33923 Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 9.1*10e-9