Query String: DESMOPRESSIN
Concentraid DDAVP Noqdirna Ddavp (Needs No Refrigeration) Presinex Minirin Octim BDBM50247923 Stimate (Needs No Refrigeration) Desmopressin Acetate Desmotabs Desmomelt Desmopressin acetate preservative free Desmospray Noctiva Desmopressin Acetate (Needs No Refrigeration) Nocutil Octostim Stimate
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide BDBM50205308 US10131692, Compound 42 (dDAVP) dDAVP DESMOPRESSIN CHEMBL1429
- In Vitro V2 Receptor Assay Agonist activity of compounds on the human V2 receptor (h V2R) was determined in a transcriptional reporter gene assay by transiently transfecting an h V2 receptor expression DNA into HEK-293 (human embryonic kidney 293 cell line) cells in concert with a reporter DNA containing intracellular calcium responsive promoter elements regulating expression of firefly luciferase. See Boss, V., Talpade, D. J., Murphy, T. J. J. Biol. Chem. 1996, May 3; 271(18), 10429-10432 for further guidance on this assay. Cells were exposed to serial dilutions of compounds diluted 10-fold per dose for 5 h, followed by lysis of cells, determination of luciferase activity, and determination of compound efficacies and EC50 values through non-linear regression. Desmopressin (dDAVP) was used as an internal control in each experiment.