BDBM23952 ESTRADIOL
BDBM25868 ESTRADIOL
ESTRADIOL BDBM22422
BDBM50270011 estradiol disulfate
Estradiol phosphate BDBM50333647 CHEMBL1642763
17beta-estradiol (E2) 17α-ethinylestradiol Ovocyclin US9561238, E2 [2,4,6,7-3H]-17beta-estradiol CHEMBL135 (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol US9034854, E2 CS336 [3H]]estradiol ESTRADIOL US9422324, E2 [2,4,6,7-3H]-E2 BDBM17292 US9040509, E2 [3H]-estradiol 17 beta-Estradiol Estradiol-17 alpha
17-ethinyl-3,17-estradiol Ethinylestradiol CHEMBL691 17alpha-ethynylestra-1,3,5(10)-triene-3,17beta-diol ETHINYL ESTRADIOL Ethynyl estradiol 17alpha-Ethinyl estradiol 17alpha-ethynylestradiol 17-ethinyl-3,17-oestradiol ethinyloestradiol 17-ethinylestradiol BDBM50187243
BDBM50016934 CHEBI:82520 ESTRADIOL MUSTARD
BDBM50423528 6-Dehydro-Estradiol CHEMBL223967
17beta-Estradiol-17-(beta-D-glucuronide) CHEMBL1697724 estradiol 17b glucuronide BDBM50344959 E17β-glucuronide
13-beta-hydroxyestradiol Estradiol BDBM50250613 CHEMBL499812
BDBM235683 US9688816, A Estradiol-17β (3)
BDBM50200937 CHEMBL219321 estradiol 3-O-sulfamate
BDBM50200938 CHEMBL220493 estradiol 17-O-sulfamate
o-NPA BDBM22723 o-nitrophenyl acetate Nitrophenyl Acetate 2-nitrophenyl acetate
BDBM50423526 CHEMBL121458 17Beta-Dihydroequillin 7-Dehydro-Estradiol
BDBM11326 4-nitrophenyl acetate p-Nitrophenyl Acetate
acetic acid, sodium salt sodium acetate CHEMBL1354 BDBM50159793 Natriumazetat anhydrous sodium acetate SODIUM ACETATE ANHYDROUS
BDBM233194 Methylprednisolone acetate
BDBM50442911 RETINYL ACETATE
NERYL ACETATE BDBM50036947
ROXATIDINE ACETATE BDBM50404032
13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(17beta-estradiol) (estradiol)13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol([6,7-3H]-estradiol) 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(estradiol) CHEMBL135 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(17alpha-estradiol) 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 17beta-Estradiol 1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one BDBM50005414 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol (estradiol) ESTRADIOL 15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-triene-5,14-diol Estradiol13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol( Estradiol)
beta-amyrinacetate CHEMBL489760 BDBM50260203 Germanicol 3-acetate beta-amyrin acetate
2-[4-(heptyloxy)phenyl]acetate [4-(heptyloxy)phenyl]acetate, 9 BDBM23440
Glutinol acetate CHEMBL487567 BDBM50275350 glutin-5-en-3-beta-O-acetate
BDBM50309556 Per-6-(estradiol-17-ethynylbenzylamino)-6-deoxy-betacyclodextrin CHEMBL604989
CHEMBL78389 B-Homo-2-ethoxy-3,17beta-estradiol-7-tosylhydrazone BDBM50089345
BDBM50430740 CHEMBL2333940 Cedryl Acetate
BDBM50439263 1-NITROSOCYCLOHEXYL ACETATE
Midecamycin BDBM50248300 Midecamycin Acetate
ULIPRISTAL ACETATE BDBM50375424 Ulipristal
(+/-)-threo-Ritalinol acetate BDBM50327104 CHEMBL1253489
ABIRATERONE ACETATE BDBM50407398 CB7630 Zytiga
BDBM50137051 [(2-ammoniopropanoyl)amino]acetate
BDBM50340426 16-Dehydropregnenolone acetate CHEMBL1761683
CHEBI:70478 BDBM50037054 CITRONELLYL ACETATE
CHEMBL1085948 ethyl bromo acetate BDBM50318514
CHEMBL1221460 Epihippuristanol 3-Acetate BDBM50482554
CHEMBL1222308 BDBM50482560 Hippuristanol 3-Acetate
Calyculin A 21-acetate (13) BDBM40780
Cortone Cortisone acetate BDBM50455157 Cortisone
GERANYL ACETATE BDBM50037025 CHEBI:5331
lupeol 3-acetate BDBM50317548 CHEMBL1097034
BDBM50248241 Cetrorelix Acetate D-20761 CHEBI:31387 Cetrotide NS-75A SB-075 Acetate Cetrorelix
2-methoxy-17beta-estradiol CHEMBL299613 BDBM50060957 Panzem 2-Hydroxyestradol 2-methyl ether
2-OH-estradiol 2-hydroxy-17beta-estradiol cid_247304 (17beta)-estra-1,3,5(10)-triene-2,3,17-triol US10864248, Compound 2 2-OH-E2 BDBM50262140 CHEMBL467987 estra-1,3,5(10)-triene-2,3,17beta-triol
BDBM50318292 CHEMBL1096975 17alpha-[2,2-Bis(ethoxycarbonyl)-1,3-dihydro-2H-inden-5-yl]-estradiol
2-(4-aminobenzamido)acetate BDBM50270006 AMINOHIPPURATE
2Alpha,10Beta-Dihydroxycedryl Acetate BDBM50430738 CHEMBL2333939
CHEBI:27750 BDBM50128823 Ethyl acetate E1504
[(3-ammoniopropanoyl)amino]acetate BDBM50137022 CHEMBL157332
6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-dien-17-yl acetate cyproterone acetate cid_9880 CHEMBL139835 Cyproterone 17-O-acetate BDBM50094569
CHEMBL1098710 BDBM50318293 17alpha-[2-Cyano-2-(ethoxycarbonyl)-1,3-dihydro-2H-inden-5-yl]-estradiol
3-cyanoquinuclidin-3-yl acetate CHEMBL1652416 BDBM50335539
BDBM50103520 GLYCINEBETAINE CHEBI:17750 2-(Trimethylammonio)Acetate
BDBM50136974 CHEMBL346341 {methyl[(methylammonio)acetyl]amino}acetate
BDBM50252742 CHEMBL493460 Isosorbide-2-benzylcarbamate-5-acetate
BDBM50321267 CHEMBL1163190 methyl 2-(o-tolyloxy)acetate
BDBM50321268 methyl 2-(2-ethylphenoxy)acetate CHEMBL1163834
BDBM50321269 methyl 2-(4-ethylphenoxy)acetate CHEMBL1163835
BDBM50321271 ethyl 2-(3-ethylphenoxy)acetate CHEMBL1163911
CHEMBL154491 BDBM50137001 [(pyrrolidinium-2-ylcarbonyl)amino]acetate
CHEMBL279115 phorbol 13-acetate 12-myristate BDBM50099066
Finaplix RU-1697 Trenbolone Acetate BDBM50190646 Trenbolone
Methyl 2-(Tert-Butoxycarbonylsulfamoylamino)Acetate BDBM50428799 CHEMBL450699
Zoladex BDBM50247974 Goserelin Acetate Novgos Zoladex LA
[(2-ammoniopropanoyl)(methyl)amino]acetate BDBM50137029 CHEMBL348602
ethyl 2-(m-tolyloxy)acetate BDBM50321270 CHEMBL1163910
Methylacetoxyprogesterone US9271961, MPA MEDROXYPROGESTERONE 6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate Medroxyprogesterone 17-acetate (6alpha)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate Medroxyacetate progesterone 6alpha-Methyl-17alpha-hydroxyprogesterone acetate medroxyprogesterone acetate 17-Acetoxy-6alpha-methylprogesterone 17alpha-Hydroxy-6alpha-methylprogesterone acetate 6-alpha-Methyl-17-alpha-acetoxyprogesterone 6alpha-Methyl-17-acetoxy progesterone Metigestrona BDBM50067678 (6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione 6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate
METHYLPHENIDATE methyl (S)-phenyl[(S)-piperidin-2-yl]acetate methyl (2S)-phenyl[(2S)-piperidin-2-yl]acetate BDBM50062909
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] acetate acetic acid [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] ester BDBM62878 MLS000069774 [(8R,9S,13S,14S,17S)-13-methyl-3-oxidanyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] ethanoate cid_6852404 SMR000058696 17BETA-ESTRADIOL 17-ACETATE
CHEMBL605828 Per-6-(estradiol-17-(1H-1,2,3-triazol-4-yl))-6-deoxy-beta cyclodextrin BDBM50309553
Concentraid DDAVP Noqdirna Ddavp (Needs No Refrigeration) Presinex Minirin Octim BDBM50247923 Stimate (Needs No Refrigeration) Desmopressin Acetate Desmotabs Desmomelt Desmopressin acetate preservative free Desmospray Noctiva Desmopressin Acetate (Needs No Refrigeration) Nocutil Octostim Stimate
CHEMBL827 methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate METHYLPHENIDATE BDBM50062915 methyl (R)-phenyl[(R)-piperidin-2-yl]acetate
BDBM50072589 CHEMBL110361 Sodium; difluoro-naphthalen-2-yl-acetate
BDBM50287711 [methyl({[(phosphonatooxy)phosphinato]oxy}acetyl)amino]acetate
CHEMBL114030 Sodium; biphenyl-3-yl-difluoro-acetate BDBM50072594
CHEMBL154651 BDBM50136980 [(2-ammonio-3-mercaptopropanoyl)amino]acetate
Substrate analogue, 16 [(ammonioacetyl)amino]acetate glycylglycine BDBM50137044
[(2-{[(phosphonatooxy)phosphinato]oxy}ethyl)thio]acetate BDBM50287712
Mono-6-(17-estradiol-17-(1H-1,2,3-triazol-4-yl))-6-deoxy-beta-cyclodextrin CHEMBL605714 BDBM50309552
3,20-Dioxopregn-4-ene-17-yl acetate (4) BDBM235654
BDBM50136976 CHEMBL152259 [(2-ammonio-3-phenylpropanoyl)(methyl)amino]acetate
BDBM50283572 Sodium; (3-carboxy-5-phosphonomethyl-phenoxy)-acetate CHEMBL262641
BDBM50283577 Sodium; (3-carboxy-5-phosphono-phenoxy)-acetate CHEMBL88094
CHEMBL1163917 ethyl 2-(4-allyl-2-methoxyphenoxy)acetate BDBM50321263
CHEMBL232590 methyl 2-(2-(4-formylphenoxy)acetamido)acetate BDBM50206195
CHEMBL247131 methyl 2-(4-chloro-2-cyclohexylphenoxy)acetate BDBM50213924
CHEMBL397101 BDBM50219225 4-(10H-phenothiazine-10-carbonyl)phenyl acetate
[methyl(2-{[(phosphonatooxy)phosphinato]oxy}ethyl)amino]acetate BDBM50287713
ethyl 2-(2-(3-phenylpropanoyl)phenoxy)acetate CHEMBL223539 BDBM50207952
methyl 2-(4-ethyl-2-nitrophenoxy)acetate CHEMBL1163201 BDBM50321272
methyl 2-(3,4-dichlorophenyl)-2-(piperidin-2-yl)acetate (RS/SR)-methyl 2-(3,4-dichlorophenyl)-2-(piperidin-2-yl)acetate CHEMBL220195 BDBM50202391
(S)-mandelic acid (2S)-hydroxy(phenyl)acetate (S)-mandelate BDBM50129063
1-(4-Cyanobenzyl)-5-(methylene-acetate)-1H-imidazole CHEMBL599222 BDBM50307236
BDBM233041 3,20-Dioxopregna-4,6-dien-17α-yl acetate (7)
BDBM237307 4-Acetamidophenyl 2-(2-(4-isobutylphenyl)propanamido)acetate (8)
BDBM23800 Triphenylmethyl-containing compound, 29 methyl 2-[(triphenylmethyl)sulfanyl]acetate
BDBM50075080 Sodium; [2-(cyclohexanesulfonylamino-methyl)-indan-5-yl]-acetate CHEMBL130460
BDBM50279380 CHEMBL453955 methyl 2-((1R,2S)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)acetate
CHEMBL1095503 3,3-Dimethylbutyl 2-(2-(2,6-Dichlorophenylamino)phenyl)acetate BDBM50316991
CHEMBL595729 2-(4,5-dichlorothiophen-3-yl)-2-oxoethyl acetate BDBM50304461
Sodium; [2-(benzenesulfonylamino-methyl)-indan-5-yl]-acetate BDBM50075086 CHEMBL341221
Sodium; [2-(phenylmethanesulfonylamino-methyl)-indan-5-yl]-acetate CHEMBL132573 BDBM50075078
(RS/SR)-methyl 2-(4-chlorophenyl)-2-(piperidin-2-yl)acetate (RR/SS)-methyl 2-(4-chlorophenyl)-2-(piperidin-2-yl)acetate BDBM50202383 CHEMBL219116
BDBM239153 Ethyl 2-(4-(naphthalen-1-ylamino)-4-oxobutanamido)acetate (5b)
BDBM50215663 4-methoxybenzyl 2-(N-(2-ethylphenyl)-4-methylphenylsulfonamido)acetate CHEMBL234600
BDBM50232253 methyl 2-(5-(benzylthio)-1,3,4-thiadiazol-2-ylthio)acetate CHEMBL252526
BDBM50272298 CHEMBL500419 (-)-N-cyclobutylmethylmorphinan-3-yl-14-ol phenoxy acetate hydrochloride
BDBM50303360 ethyl 2-(3,3-Diethyl-2,4-dioxoazetidin-1-yl)acetate CHEMBL271820
BDBM50306746 CHEMBL599548 3-(5-amino-4-carbamoyloxazol-2-yl)phenyl acetate
CHEMBL1095189 2-(Trimethylsilyl)ethyl 2-(2-(2,6-Dichlorophenylamino)phenyl)acetate BDBM50316990
CHEMBL1163189 Methyl 2-(5-hydroxy-2-methoxy-4-propylphenoxy)acetate BDBM50321274
CHEMBL1164144 BDBM50321273 Methyl 2-(5-amino-2-methoxy-4-propylphenoxy)acetate
CHEMBL133420 Sodium; [2-(4-chloro-benzenesulfonylamino)-indan-5-yl]-acetate BDBM50075089
CHEMBL213132 BDBM50189971 methyl 2-(4-(3-(2-propylphenoxy)propoxy)phenoxy)acetate
CHEMBL494130 4-(4-(6-chloroquinazolin-4-ylamino)butoxy)phenyl acetate BDBM50257748
ethyl 2-oxo-2-(4-styrylpyrimidin-2-ylamino)acetate CHEMBL1209746 BDBM50323584
BDBM50250299 (9Z,11S,16R)-dihydroxyoctadeca-9,17-dien-12,14-diyn-1-yl acetate 11(S),16(R)-dihydroxyoctadeca-9Z,17-diene-12,14-diyn-1-yl acetate CHEMBL490698
methyl 2-(3-benzamidophenoxy)ethanoate methyl [3-(benzoylamino)phenoxy]acetate 2-(3-benzamidophenoxy)acetic acid methyl ester SMR000077931 BDBM40879 MLS000064918 methyl 2-(3-benzamidophenoxy)acetate cid_973374
Butyl(2,4-dichlorophenoxy) acetate 2-(2,4-dichlorophenoxy)acetic acid butyl ester butyl 2-(2,4-dichlorophenoxy)acetate BDBM74250 SMR001224484 cid_7206 MLS002152860 butyl 2-[2,4-bis(chloranyl)phenoxy]ethanoate
Sodium; [2-(2,6-dichloro-phenylamino)-phenyl]-acetate ARTHROTEC US11173137, Compound Diclofenac SOLARAZE diclofenac sodium VOLTAREN-XR sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate GP 45840 BDBM50174201 VOLTAREN
(E) Ethyl [2-(4-oxo-6-phenylhex)-5-enamido]acetate (3c) BDBM239141
(Z/E)-ethyl 2-((2-oxoindolin-3-ylidene)methylamino)acetate CHEMBL1689594 BDBM50339262
11-methyl-6,11-dihydrothiochromeno[4,3-b]indol-8-yl acetate BDBM50185201 CHEMBL207510
2-(2-Acetoxy-5-(2-chloroethyl)benzyl)-4-ethylphenyl acetate CHEMBL1254859 BDBM50326695
2-(5-(Biphen-4-ylsulfonamido)-1,3,4-thiadiazol-2-yl)acetate CHEMBL1685061 BDBM50338962
3,20-Dioxo-6,7-epoxypregn-4-ene-7α-yl acetate (8) BDBM233042
6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl acetate (9) BDBM233043
Acetic acid 4-allyl-2-methoxy-phenyl ester CHEMBL108299 BDBM50240728 eugenyl acetate
BDBM234419 (S)-Ethyl 2-(2-(2-aminopropanamido)thiazol-4-yl)acetate (4b)
BDBM50009995 2-(1-naphthamido)acetate CHEMBL306898 [(Naphthalene-1-carbonyl)-amino]-acetic acid
BDBM50075083 CHEMBL340073 Sodium; {2-[(pentane-1-sulfonylamino)-methyl]-indan-5-yl}-acetate
BDBM50075090 CHEMBL422441 Sodium; {2-[(naphthalene-1-sulfonylamino)-methyl]-indan-5-yl}-acetate
BDBM50251901 ethyl 2-(2-(2-(phenylsulfonyl)acetamido)thiazol-4-yl)acetate CHEMBL479404
BDBM50269234 CHEMBL526931 12-O-[3-methyl-2-butenoyl]-4-deoxyphorbol 13-acetate
BDBM50478510 CHEBI:70418 3-Acetylaleuritolic Acid Acetyl Aleuritolic Acid Maprounic Acid Acetate
CHEMBL131497 BDBM50075077 Sodium; {2-[(naphthalene-2-sulfonylamino)-methyl]-indan-5-yl}-acetate
CHEMBL134128 Sodium; {2-[(pyridine-3-sulfonylamino)-methyl]-indan-5-yl}-acetate BDBM50075087
CHEMBL1642285 methyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetate BDBM50334624
CHEMBL1779733 4-(5-(2,5-dichlorophenyl)furan-2-carboxamido)-3,5-dimethylbenzyl acetate BDBM50344798
CHEMBL335043 Sodium; {2-[(thiophene-2-sulfonylamino)-methyl]-indan-5-yl}-acetate BDBM50075076
CHEMBL384671 BDBM50209080 methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-4-yl)acetate
CHEMBL462629 ethyl 2-cyano-2-(quinoxalin-2(1H)-ylidene)acetate BDBM50247466 cid_5600879
CHEMBL493805 (E)-methyl 2-(1-dodecyl-2-oxoindolin-3-ylidene)acetate BDBM50261104
CHEMBL526339 BDBM50272319 Methyl [5-(6-methoxynaphthalen-2-yl)pyridin-3-yl]acetate
CHEMBL564664 BDBM50296433 benzyl 2-(5-(2-fluorophenyl)-1,3,4-oxadiazol-2-ylthio)acetate
Corticotropin Tetracosapeptide COSYNTROPIN Cortrosyn Vicotrope BDBM50017180 CHEBI:3901 Tetracosactide Acetate Tetracosactide Tetracosactrin
Sodium; {2-[(4-chloro-benzenesulfonylamino)-methyl]-indan-5-yl}-acetate BDBM50075088 CHEMBL336846
ethyl 2-(2-(3-(styrylthio)propanamido)thiazol-4-yl)acetate BDBM50191455 CHEMBL213901
BDBM20624 (1S,10R,11S,14R,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol 17alpha-estradiol
CHEMBL132589 FR-181157 Sodium; {3-[(S)-2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate Sodium; {3-[2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate BDBM50136234 Sodium; {3-[(R)-2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate sodium (S)-2-(3-((2-(4,5-diphenyloxazol-2-yl)cyclohex-2-enyl)methyl)phenoxy)acetate
(4-formylphenyl) 2-(4-fluorophenyl)acetate 4-formylphenyl (4-fluorophenyl)acetate (4-methanoylphenyl) 2-(4-fluorophenyl)ethanoate MLS001180493 2-(4-fluorophenyl)acetic acid (4-formylphenyl) ester BDBM63940 cid_820021 SMR000477394
Ethyl 2-(2-((2S,3R)-2-amino-3-methylpentanamido)thiazol- 4-yl)acetate (7b) Ethyl 2-(2-((2S,3R)-2-amino-3-methylpentanamido)thiazol-4-yl)acetate (5b) BDBM234423
Isoquinoline-1,3,4-trione 6k 2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate BDBM10264 phenyl[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)carbamoyl]methyl acetate
RS-26306 GANIRELIX ACETATE Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu-Har(Et2)-Pro-DAla-NH2 CHEMBL1251 Ganirelix acetate injection BDBM50102454 Ganirelix
sodium 2-(3-((2-(4,5-diphenyloxazol-2-yl)cyclohex-1-enyl)methyl)phenoxy)acetate Sodium; {3-[2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-1-enylmethyl]-phenoxy}-acetate BDBM50136237 CHEMBL132649
(E)-Ethyl 2-(6-(3,4-dimethoxyphenyl)-4-oxohex-5-enamido)acetate (3h) BDBM239146
(R)-methyl 2-(2-fluorophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327161 CHEMBL1253310
(R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327157 CHEMBL1179011
(R)-methyl 2-(3,4-dimethoxyphenyl)-2-((R)-piperidin-2-yl)acetate CHEMBL1254516 BDBM50327158
(R)-methyl 2-(3-chlorophenyl)-2-((R)-piperidin-2-yl)acetate CHEMBL1253271 BDBM50327155
(R)-methyl 2-(3-fluorophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327162 CHEMBL1253311
(R)-methyl 2-(4-aminophenyl)-2-((R)-piperidin-2-yl)acetate CHEMBL1253709 BDBM50327143
(R)-methyl 2-(4-chlorophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327145 CHEMBL1178924
(R)-methyl 2-(4-fluorophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327156 CHEMBL1253289
(R)-methyl 2-(4-hydroxyphenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327139 CHEMBL1253698
(R)-methyl 2-(4-nitrophenyl)-2-((R)-piperidin-2-yl)acetate CHEMBL1254439 BDBM50327141
(S)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186436 CHEMBL209822
3-hydroxy-17-oxooestra-1,3,5(10)-trien-11a-yl acetate BDBM264476 US9714266, 5
4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin-4-ylamino)benzamido)acetate CHEMBL605981 BDBM50307799
4-methoxyphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate CHEMBL211822 BDBM50186433
BDBM50075084 CHEMBL130170 Sodium; {2-[3-(4-chloro-benzenesulfonylamino)-propyl]-indan-5-yl}-acetate
BDBM50075094 CHEMBL132659 Sodium; {2-[2-(4-chloro-benzenesulfonylamino)-ethyl]-indan-5-yl}-acetate
BDBM50085853 Sodium; [2-cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-o-tolyl-acetate CHEMBL173251
BDBM50120471 CHEMBL148054 ethyl 2-[1'-benzylspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]-3-yl]acetate
BDBM50191136 CHEMBL386580 sodium 2-(3-(2-(4,5-diphenyloxazol-2-yl)benzyl)phenoxy)acetate
BDBM50296317 (3R)-1-Azabicyclo[2.2.2]oct-3-ylhydroxy(di-2-thienyl)acetate CHEMBL551729
BDBM50307792 CHEMBL597562 4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin-4-ylamino)phenyl)acetate
BDBM50327142 (R)-methyl 2-(3-aminophenyl)-2-((R)-piperidin-2-yl)acetate CHEMBL1253708
BDBM50327160 CHEMBL1187951 (R)-methyl 2-(2-chlorophenyl)-2-((R)-piperidin-2-yl)acetate
BDBM50328804 rac-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-yl acetate CHEMBL1269951
CHEBI:474180 L-743,872 Caspofungin Acetate Cancidas Caspofungin MK-991 BDBM50478215 L-743872
CHEMBL1087206 BDBM50316980 4-((3,3-Dimethylbutoxy)carbonyloxy)benzyl 2-(2-(2,6-Dichlorophenylamino)phenyl)acetate
CHEMBL1170333 (R)-ethyl 2-(1'-benzylspiro[isochroman-1,4'-piperidine]-3-yl)acetate BDBM50321771
CHEMBL1253270 BDBM50327154 (R)-methyl 2-(3-hydroxyphenyl)-2-((R)-piperidin-2-yl)acetate
CHEMBL1253735 (R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327148
CHEMBL1253736 (R)-methyl 2-(3-bromophenyl)-2-((R)-piperidin-2-yl)acetate BDBM50327149
CHEMBL1269433 BDBM50329092 (Z)-methyl 2-(3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene)acetate
CHEMBL1783784 ethyl 2-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)acetate BDBM50346159
CHEMBL225273 3-(6-morpholino-4-oxo-4H-pyran-2-yl)benzyl acetate BDBM50208548
CHEMBL255013 BDBM50235104 methyl 2-(2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethoxy)phenoxy)acetate
CHEMBL255228 methyl 2-(2-(1-phenylcyclohexyl)-4-(quinolin-2-ylmethoxy)phenoxy)acetate BDBM50235115
CHEMBL496452 BDBM50269198 9alpha,11alpha-epoxycholest-7-ene-3beta,5alpha,6alpha-triol 6-acetate
CHEMBL502799 12-O-[(2R)-N,N-dimethyl-3-methylbutanoyl]phorbol 13-acetate BDBM50269235
Ethyl 2-(3-(3-(difluoromethyl)-1H-pyrazol-5-yl)phenoxy)acetate (3c) BDBM231672
Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)phenoxy)acetate (3b) BDBM231671
Etynodiol Ethynodiol Diacetate Etynodiol diacetate Etynodiol Acetate BDBM50237627 Femulen CHEBI:31580 SC-11800
Megace BDBM50238674 SC-10363 BDH-1298 Megestrol Megestrol Acetate 5071 Ovaban Megace Es
N-Methoxycarbonyl-D-norleucyl-glycyl-L-arginine-4- nitranilide-acetate BDBM31507 Chromozym X
Sodium; {2-[4-(4-chloro-benzenesulfonylamino)-butyl]-indan-5-yl}-acetate BDBM50075095 CHEMBL131336
US9815796, Example 4 BDBM354913 2-Methyl-2-(1H-pyrazol-1-yl)propanimidamide acetate
ethyl 2-(2-(3-(3,4-dichlorophenyl)ureido)thiazol-4-yl)acetate BDBM50336541 CHEMBL1673336
ethyl 2-(4-chloro-2-(3,4,5-trimethoxyphenylamino)pyrimidin-5-yl)acetate BDBM50182011 CHEMBL206796
ethyl 2-(5H-imidazo[5,1-a]isoindol-5-yl)acetate US10233190, Example 1256 BDBM370420
methyl 2-{4-(beta-D-galactopyranosyl)-[1,2,3]triazole-2-ylmethyl}acetate BDBM50272146 CHEMBL502002
Methyl 2,3-Dihydro-2-thioxo-1H-indole-3-acetate 2-thioxo-1H-indole-3-alkanoic acid deriv. 7 BDBM3958 methyl 2-(2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetate
(E)-Ethyl 2-(6-(4-(benzyloxy)phenyl)-4-oxohex-5-enamido)acetate (3k) BDBM239149
(R)-methyl 2-(2-chlorophenyl)-2-((R)-piperidin-2-yl)acetate hydrochloride CHEMBL534500 BDBM50212388
(S)-methyl 2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetate CHEMBL245917 BDBM50210528
13-methylcarbonyloxy-20-azapentacyclo[7.6.5.02,7.010,15.016,20]icosa-2(7),3,5,12,14-pentaen-4-yl acetate BDBM50122554
4-((2-(Trimethylsilyl)ethoxy)carbonyloxy)benzyl 2-(2-(2,6-Dichlorophenylamino)phenyl)acetate BDBM50316979 CHEMBL1088643
BDBM234418 (S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)propanamido)thiazol-4-yl)acetate (4a)
BDBM234427 (S)-Ethyl 2-(2-(2-amino-3-methylbutanamido)thiazol-4-yl)acetate (6b)
BDBM234439 (S)-Ethyl 2-(2-(2-amino-3-phenylpropanamido)thiazol-4-yl)acetate (9b)
BDBM50143930 (3-Cyclohexyl-ureido)-acetic acid methyl ester CHEMBL66518 methyl 2-(3-cyclohexylureido)acetate
BDBM50186427 methyl 2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate CHEMBL212313
BDBM50186429 US8618147, 13 butyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate CHEMBL210755
BDBM50189965 CHEMBL211963 methyl 2-(4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetate
BDBM50248097 2-(4-((2,4-dichlorobenzamido)methyl)-1-(propylsulfonyl)piperidin-4-yl)cyclohexyl acetate CHEMBL462147
BDBM50256074 butyl 2-(4,5-bis(2,4-dichlorophenyl)-2H-1,2,3-triazol-2-yl)acetate CHEMBL481885
BDBM50256540 (S)-N-(2-(4,5-dihydro-1H-imidazol-5-yl)ethyl)acetamide acetate CHEMBL480572
BDBM50273231 ethyl 2-(N-(4-isopropylphenethyl)-2-hydroxy-5-(N'-hydroxycarbamimidoyl)phenylsulfonamido)acetate CHEMBL455919
BDBM50298224 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate CHEMBL265470
BDBM50298487 CHEMBL583989 4-(4-(5-oxothiophen-2(5H)-ylidene)hexan-3-yl)phenyl acetate
BDBM50308373 CHEMBL589064 (E)-methyl 2-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)acetate
BDBM50327107 CHEMBL1183494 (R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-yl)acetate
BDBM50327146 CHEMBL1254440 (R)-methyl 2-(4-tert-butylphenyl)-2-((R)-piperidin-2-yl)acetate
BDBM50327726 CHEMBL1257397 methyl 2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetate
BDBM50338956 Ethyl 2-(5-(4-Dodecylphenylsulfonamido)-1,3,4-thiadiazol-2-yl)acetate CHEMBL1685055 US9320734, 120E
BDBM533328 (3-{4-[(3-piperidylpropyl)amino]-2- quinolyl}phenyl)methyl acetate US11220486, Compound I258
BR30 BDBM12418 copper(2+) ion 2-[(carboxylatomethyl)({2-[(4-sulfamoylphenyl)formamido]ethyl})amino]acetate
CHEMBL1172971 2-(naphthalen-2-yl)-2-oxoethyl 2-(2-(o-tolyloxy)acetamido)acetate BDBM50322735
CHEMBL1224717 BDBM50325790 methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)phenyl)acetate
CHEMBL1254844 BDBM50327108 (R)-methyl 2-((R)-piperidin-2-yl)-2-(4-(trifluoromethyl)phenyl)acetate
CHEMBL131036 BDBM50075085 Sodium; {2-[(4-chloro-benzenesulfonylamino)-methyl]-2,3-dihydro-benzofuran-5-yl}-acetate
CHEMBL208716 US8618147, 12 BDBM50186425 isopropyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
CHEMBL210194 ethyl 2-(2-(3-nitrobenzamido)-1H-benzo[d]imidazol-1-yl)acetate BDBM50184695
CHEMBL210592 neopentyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate US8618147, 16 BDBM50186443
CHEMBL211882 BDBM50186444 neopentyl 2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
CHEMBL377184 cyclohexylmethyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate US8618147, 15 BDBM50186430
CHEMBL378265 BDBM50186435 US8618147, 5 mesityl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
CHEMBL378460 3-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)propyl acetate BDBM50183086
Ethyl 2-(5-(4-Decanamidophenylsulfonamido)-1,3,4-thiadiazol-2-yl)acetate US9320734, 119E CHEMBL1685042 BDBM50338942
N-Methylsulfonyl-D-Phe-Gly-Arg-4-nitranilide acetate Factor VII Chromogenic Substrate BDBM14496
Sodium; (1-benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yloxy)-acetate CHEMBL148500 BDBM50055346
US8618147, 10 ethyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186442 CHEMBL208658
US8618147, 2 phenyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186424 CHEMBL377038
cyclohexyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186445 US8618147, 14 CHEMBL209401
ethyl 2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetate BDBM50327727 CHEMBL1257398
methyl 2-((2S,4S)-4-(3,4,5-trimethoxybenzamido)-1-acetylpyrrolidine-2-carboxamido)acetate BDBM50247523 CHEMBL473732
methyl [1'-(cyclopropylmethyl)-2-oxospiro[indole-3,4'-piperidin]-1(2H)-yl]acetate CHEMBL383561 BDBM50173279
propyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186439 US8618147, 11 CHEMBL208659
methyl phenidylacetate BDBM50062912 methyl alpha-phenyl-alpha-(2-piperidyl)acetate alpha-phenyl-2-piperidineacetic acid methyl ester methyl phenyl(piperidin-2-yl)acetate methylphenidan methyl alpha-phenyl-alpha-2-piperidinylacetate CHEMBL796 Methylphenidate
MLS000583399 SMR000185924 BDBM33729 acetic acid (6-methoxy-3-quinolyl) ester (6-methoxyquinolin-3-yl) acetate (6-methoxyquinolin-3-yl) ethanoate acetic acid (6-methoxy-3-quinolinyl) ester cid_867308 6-methoxy-3-quinolinyl acetate
Hemsol-Hc BDBM50474607 Micort-Hc Hydrocortisone 21-acetate Neo-Cortef CHEBI:17609 NSC-741 Gppe Eye Crm Dricort Cortucid Hepacort Plus Orabase Hca Epifoam Genticin HC Barquinol HC Gentisone HC Framycort Hc45 Hydrocort Hydrocortone Gppe Foam Aero Chloromycetin Hydrocort Lanacort Hydrocortisone Acetate Cortifoam Gppe Ear Susp Cortril Fucidin H Cortef Acetate Colifoam Hydrocal
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetylamino) acetate CHEMBL429267 BDBM50226647
(3-(4-(3-chlorophenylamino)quinazolin-6-yl)-1-methyltriaz-2-enyl)methyl acetate BDBM50301421 CHEMBL571809
(4-anilinophenyl) acetate cid_2337865 SMR000353326 (4-phenylazanylphenyl) ethanoate MLS001002014 acetic acid (4-anilinophenyl) ester BDBM47972
(R)-ethyl 2-(1'-benzyl-3H-spiro[isobenzofuran-1,4'-piperidine]-3-yl)acetate CHEMBL1172094 BDBM50321760
(S)-Ethyl-2-(3-(2-aminoacetamido)-2,6-dioxopiper idin-1-yl)acetate hydrochloride BDBM50316380 CHEMBL1095916
1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)ethyl acetate BDBM370501 US10233190, Example 1420
3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-thiobutyramide; Trifluoro acetate BDBM50022742 CHEMBL67868
4-Acetamidophenyl 2-(2-(4-(2-(trifluoromethyl)pyridin-4-ylamino)phenyl)acetamido)acetate BDBM50307797 CHEMBL599823
5-oxo-1-tosyl-2,5-dihydro-1Hpyrrol-2-yl acetate BDBM50321258 CHEMBL1164744 CA inhibitor, 17
BDBM233181 Sodium [5-hydroxy-5-(2-methoxy-quinolin-3-yl)-pent-2-ynyloxy]-acetate (18b)
BDBM234426 (S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)-3-methylbutanamido)thiazol-4-yl) acetate (6a)
BDBM234430 (S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)-4-methylpentanamido)thiazol-4-yl) acetate (7a)
BDBM234435 (S)-Ethyl 2-(2-(2-amino-4-(methylthio)butanamido)thiazol-4-yl)acetate (8b)
BDBM234438 (S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)-3-phenylpropanamido)thiazol-4-yl) acetate (9a)
BDBM26745 bisarylimidazole derivative, 4 methyl 2-[3-(4,5-diphenyl-1H-imidazol-1-yl)phenoxy]acetate
BDBM50068691 CHEMBL149152 Lithium; [6-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4'-isobutyl-biphenyl-2-yloxy]-acetate
BDBM50085833 CHEMBL172144 Sodium; [5-(benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]-o-tolyl-acetate
BDBM50121754 CHEMBL12488 amino[(2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2-d]pyrimidin-7-yl)amino]methaniminium acetate
BDBM50129068 (R)-mandelate (R)-2-Hydroxy-2-phenylacetate (2R)-hydroxy(phenyl)acetate (R)-mandelic acid
BDBM50206173 CHEMBL241281 (E)-7-((3,4-dihydroisoquinolin-2(1H)-yl)methyleneamino)-1,2,3,4-tetrahydronaphthalen-1-yl acetate
BDBM50207968 CHEMBL223462 1-(2-(3-phenylpropanoyl)phenoxy)-3-(piperidin-1-yl)propan-2-yl acetate
BDBM50224132 ethyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-(phenyl)-1H-pyrrol-3-acetate CHEMBL238031
BDBM50251902 CHEMBL479405 ethyl 2-(3-hydroxy-2-(2-(phenylsulfonyl)acetamido)-2,3-dihydrothiazol-4-yl)acetate
BDBM50305804 CHEMBL593268 4-(4-(4-(methylsulfonyl)phenyl)-2,5-dioxo-2,5-dihydrofuran-3-yl)phenyl acetate
BDBM50307022 4-(2-((Z)-3-(3,5-dibromo-4-hydroxyphenyl)-2-methoxyacrylamido)vinyl)phenyl acetate CHEMBL601642
BDBM50310260 Heptyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate CHEMBL599524
BDBM50310266 Hexadecyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate CHEMBL598307
BDBM50310267 Octadecyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate CHEMBL597096
BDBM50310268 CHEMBL591495 Icosyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate
BDBM50316381 Ethyl-2-((S)-3-((S)-2-aminopropanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride CHEMBL1095917
BDBM50316390 CHEMBL1095914 Ethyl-2-((S)-3-((S)-2,6-diaminohexanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride
BDBM50318060 CHEMBL1096050 7-(6-(nitrooxy)hexyloxy)-4-oxo-2-phenyl-4H-chromen-5-yl acetate
BDBM526286 US11186554, Compound 7 ethyl 2-[5-[2-(4-fluoroanilino)phenyl]tetrazol-2- yl]acetate
CHEMBL1093140 BDBM50315768 5-bromo-4-methoxy-2-(((1S)-2,2,5-trimethyl-6-methylenecyclohexyl)methyl)phenyl acetate
CHEMBL1097729 7-(4-(nitrooxy)butoxy)-4-oxo-2-phenyl-4H-chromen-5-yl acetate BDBM50318059
CHEMBL119069 ethyl [({hydroxy[(6-phenoxy-2H-chromen-3-yl)methyl]amino}carbonyl)amino]acetate BDBM50042522
CHEMBL194984 BDBM50173951 N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-5-phenylthiophene-2-carboxamide acetate
CHEMBL240025 BDBM50206183 (E)-6-((benzyl(methyl)amino)methyleneamino)-2,3-dihydro-1H-inden-1-yl acetate
CHEMBL274649 amino[(2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2-d]pyrimidin-6-yl)amino]methaniminium acetate BDBM50121758
CHEMBL373785 methyl 2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetate BDBM50189970
CHEMBL599618 BDBM50307798 4-Acetamidophenyl 2-(3-methyl-4-(2-(trifluoromethyl)pyridin-4-ylamino)benzamido)acetate
CHEMBL599728 Decyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate BDBM50310263
CHEMBL603968 BDBM50310261 Octyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate
Dodecyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate BDBM50310264 CHEMBL598305
Ethyl 2-(2-((2S,3R)-2-amino-3-methylpentanamido)thiazol- 4-yl)acetate (7b) BDBM234431
Hexyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate BDBM50310259 CHEMBL591213
Isopropyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-phenyl-1H-pyrrole-3-acetate CHEMBL605820 BDBM50308732
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-5-phenylthiophene-2-carboxamide acetate BDBM50173956 CHEMBL370535
Nonyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate CHEMBL599145 BDBM50310262
Sodium [5-hydroxy-5-(2-pentyloxy-quinolin-3-yl)-pent-2-ynyloxy]-acetate (18a) BDBM233180
Tetradecyl 2-(5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)acetate CHEMBL598306 BDBM50310265
US10266526, Compound 122 BDBM377994 ethyl 2-(2-oxoindoline-5-carboxamido)-2-(piperidin-4-yl)acetate
bisarylimidazole derivative, 1 methyl 2-[4-(4,5-diphenyl-1H-imidazol-1-yl)phenoxy]acetate BDBM26742
ethyl 2-(4-(pyridin-2-ylamino)-2-(3,4,5-trimethoxyphenylamino)pyrimidin-5-yl)acetate BDBM50181987 CHEMBL204933
ethyl 2-[1'-benzylspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-3-yl]acetate BDBM50120473 CHEMBL148236
isopropyl 2-(4-benzyl-5-(2-methoxyphenyl)-4H-1,2,4-triazol-3-ylthio)acetate BDBM50296417 CHEMBL561592
methyl 2-(4-(5-(3-acetamidobut-1-ynyl)thiazol-2-yloxy)phenoxy)acetate BDBM50195030 CHEMBL220007
methyl 2-(4-benzyl-5-(2-hydroxyphenyl)-4H-1,2,4-triazol-3-ylthio)acetate CHEMBL563744 BDBM50296416
methyl 2-(4-chloro-2-(2-(3-(diisobutylcarbamoyl)-5-methylphenoxy)ethyl)phenoxy)acetate CHEMBL1682773 BDBM50337487
Methyl 2,3-Dihydro-l-methyl-2-thioxo-1H-indole-3-acetate methyl 2-(1-methyl-2-sulfanylidene-2,3-dihydro-1H-indol-3-yl)acetate 2-thioxo-1H-indole-3-alkanoic acid deriv. 8 BDBM3959
[4-[(phenylsulfonylhydrazinylidene)methyl]phenyl] ethanoate cid_875541 SMR000298281 acetic acid [4-[(benzenesulfonylhydrazinylidene)methyl]phenyl] ester BDBM57819 [4-[(benzenesulfonylhydrazinylidene)methyl]phenyl] acetate acetic acid [4-[(besylhydrazono)methyl]phenyl] ester 4-[2-(phenylsulfonyl)carbonohydrazonoyl]phenyl acetate MLS000673752
dithiobis(1H-indole-3-alkanoic acid) deriv. 22 BDBM3974 methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1H-indol-2-yl]disulfanyl}-1H-indol-3-yl)acetate Dimethyl 2,2 -Dithiobis(1H-indole-3-acetate)
methyl 2-[2-({[3-(2-methoxy-2-oxoethyl)-1H-indol-2-yl]sulfanyl}disulfanyl)-1H-indol-3-yl]acetate Dimethyl 2,2 -Trithiobis(1H-indole-3-acetate) dithiobis(1H-indole-3-alkanoic acid) deriv. 26 BDBM3978
(R)-4-(4-(4-benzoyl-2-methylpiperazin-1-yl)phthalazin-1-yl)phenyl acetate CHEMBL1209189 BDBM50323132
(S)-Ethyl 2-(2-(2-(tert-butoxycarbonylamino)-4-(methylthio)butanamido)thiazol-4-yl) acetate (8a) BDBM234434
(S)-Methyl 2-(2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetamido)acetate CHEMBL246179 BDBM50210541
16,17-dimethyl-13-methylcarbonyloxy-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaen-4-yl acetate BDBM50122519
2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-oxoethyl 2-(4-chlorobenzamido)acetate CHEMBL1172972 BDBM50322736
3-{[(1,1,2,2,3,3,4,4,4-nonafluorobutyl)sulphonyl]oxy}-17-oxooestra-1,3,5(10)-trien-11a-yl acetate BDBM264477 US9714266, 6
BDBM50084103 CHEMBL76530 Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-oct-1-enyl)-cyclohexyl]-acetate
BDBM50168291 CHEMBL363350 Sodium; {3-[(S)-2-(4,5-diphenyl-oxazol-2-yl)-cyclopent-2-enylmethyl]-phenoxy}-acetate
BDBM50191134 sodium 2-(3-(((1S,2S)-2-(4,5-diphenyloxazol-2-yl)cyclopentyl)methyl)phenoxy)acetate CHEMBL379203
BDBM50191135 CHEMBL215442 sodium 2-(3-(((1S,2R)-2-(4,5-diphenyloxazol-2-yl)cyclopentyl)methyl)phenoxy)acetate
BDBM50191137 sodium 2-(3-(((1S,2R)-2-(4,5-diphenyloxazol-2-yl)cyclohexyl)methyl)phenoxy)acetate CHEMBL212943
BDBM50253831 CHEMBL505334 Methyl 2-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole-2-ylthio)acetate
BDBM50263002 CHEMBL515637 (2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)acetate
BDBM50265313 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropyl acetate CHEMBL498600
BDBM50265487 2-(benzofuran-2-yl)-4-oxo-4H-benzo[d][1,3]oxazin-6-yl acetate CHEMBL498412
BDBM50273264 ethyl 2-(2-(2-(2-hydroxy-5-(N'-hydroxycarbamimidoyl)phenylsulfonamido)ethyl)-5-isopropylphenoxy)acetate CHEMBL457632
BDBM50322740 CHEMBL1173692 2-(4-chloro-2-(trifluoromethyl)phenylamino)-2-oxo-1-phenylethyl 2-(4-chlorobenzamido)acetate
BDBM50326569 methyl 2-(4-methyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-ylthio)acetate CHEMBL1253492
BDBM50329093 (Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]thiazin-3(4H)-ylidene)acetate CHEMBL1269474
CHEMBL1171525 BDBM50321533 methyl 2-(N-(2-(4-fluorobenzamido)-4-methoxybenzo[d]thiazol-7-yl)acetamido)acetate
CHEMBL1269380 (Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate BDBM50329094
CHEMBL148479 BDBM50055334 Sodium; [3-carbamoylmethyl-1-(3-chloro-benzyl)-2-methyl-1H-indol-4-yloxy]-acetate
CHEMBL1668289 2-bromo-4-((1-(4-bromophenyl)-3,5-dioxopyrazolidin-4-ylidene)methyl)-6-methoxyphenyl acetate BDBM50336422
CHEMBL1778904 BDBM50344615 Ethyl-(E)-2-(4-(3-(5-Bromo-4-hydroxy-2-methoxyphenyl)acryloyl)phenoxy)acetate
CHEMBL205071 ethyl 2-({N'-[(1E,2S)-2-{[(tert-butoxy)carbonyl]amino}hexylidene]hydrazinecarbonyl}amino)acetate BDBM50177507
CHEMBL214394 BDBM50189964 methyl 2-(2-methyl-4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetate
CHEMBL497598 BDBM50265470 (R)-tert-butyl 2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate
DAGO ACETATE SALT BDBM82089 CAS_ 100929-53-1 D-Ala2-MePhe4-Met(0)5-enkephalin-ol
Ethyl 2-(2-((2S,3R)-2-(tert-butoxycarbonylamino)-3-methylpentanamido)thiazol-4-yl)acetate (5a) BDBM234422
Methyl 2-(4-((2-cyclopentyl-6-ethylpyrimidin-4-yl)methyl)phenyl)acetate US11401286, Example 223 BDBM562651
Sodium; (1-biphenyl-2-ylmethyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yloxy)-acetate BDBM50055305 CHEMBL423762
Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-undec-1-enyl)-cyclohexyl]-acetate CHEMBL80541 BDBM50084101
Sodium; [1-hydroxy-3-((E)-3-hydroxy-7-phenyl-hept-1-enyl)-cyclohexyl]-acetate BDBM50087682 CHEMBL354872
US11186554, Compound 18 BDBM526294 Ethyl 2-[4-[2-[3- (trifluoromethyl)anilino]phenyl]triazol-1- yl]acetate
US11220486, Compound I65 BDBM533135 ethyl 2-[(4-{4-[(3-piperidylpropyl)amino]-2- quinolyl}phenyl)carbonylamino]acetate
US8618147, 4 4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate BDBM50186432 CHEMBL211823
ethyl 2-((3R,5S)-4-(4-amino-3,5-dichlorobenzoyl)-3,5-dimethylpiperazin-1-yl)acetate CHEMBL222317 BDBM50195486
ethyl 2-(2-methyl-3,5-dioxo-1,2,4-thiadiazolidin-4-yl)acetate BDBM7852 Thiadiazolidinone (TDZD) deriv. 59
methyl 2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclopropylbenzamido)-N-methylcyclohexanecarboxamido)acetate CHEMBL426208 BDBM50195498
methyl 2-(5-(4- phenylquinolin-2- yl)thiophen-2-yl)acetate US10995070, Formula IId-i BDBM495031
methyl 2-[(4-{4-[(3-piperidylpropyl)amino]-2- quinolyl}phenyl)carbonylamino]acetate US11220486, Compound I69 BDBM533139
n-Butyl-2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-phenyl-1H-pyrrole-3-acetate BDBM50308736 CHEMBL602237
sodium 2-(3-(((1S,2S)-2-(4,5-diphenyloxazol-2-yl)cyclohexyl)methyl)phenoxy)acetate BDBM50191138 CHEMBL405770
(+)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)pentanamido] acetate (Compound 22) BDBM115177 (−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)pentanamido]acetate (Compound 23)
BDBM50159804 CHEMBL221802 estradiol 3,17-O,O-bis-sulfamate sulfamic acid (8R,9S,13S,14S,17S)-13-methyl-3-sulfamoyloxy-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl ester
BDBM50204955 methyl{[4-(benzoylamino)-5-({2-[(benzoyl)amino]-1,3-thiazol-4-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate CHEMBL388906 methyl 2-(4-benzamido-5-((2-benzamidothiazol-4-yl)methyl)-4H-1,2,4-triazol-3-ylthio)acetate
methyl 2-(5-((2-acetamidothiazol-4-yl)methyl)-4-benzamido-4H-1,2,4-triazol-3-ylthio)acetate BDBM50204979 methyl{[4-(benzoylamino)-5-({2-[(acetyl)amino]-1,3-thiazol-4-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate CHEMBL243704
((2E)-3-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-1-methyltriaz-2-enyl)methyl acetate BDBM50136228 CHEMBL152922
(E)-7-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyleneamino)-1,2,3,4-tetrahydronaphthalen-1-yl acetate CHEMBL240022 BDBM50206165
(S)-Benzyl-2-(2-(3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl))acetate BDBM50323943 CHEMBL1214593
(S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)amino)pyrrolidin-1-yl)acetate CHEMBL559261 BDBM50298033
(S)-tert-butyl 2-(6-isopropyl-1-methyl-4,7-dioxo-1,3,5-triazepan-3-yl)acetate CHEMBL385572 BDBM50200325
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 2-(tert-butoxycarbonylamino)acetate CHEMBL564008 BDBM50293323
2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]ethyl acetate BDBM50173253 CHEMBL373190
ATC [2-(acetylsulfanyl)ethyl]trimethylazanium iodide acetylthiocholine chloride Acetylthiocholine acetylthiocholine iodide (2-Mercaptoethyl)trimethylammonium iodide acetate BDBM8959
BDBM12415 copper(2+) ion 2-[(carboxylatomethyl)[(4-{[2-(4-sulfamoylphenyl)ethyl]carbamoyl}phenyl)methyl]amino]acetate BR15
BDBM19959 3-arylquinazolinethione, 1bg 5-(acetyloxy)-3-[4-(acetyloxy)phenyl]-4-sulfanylidene-3,4-dihydroquinazolin-7-yl acetate
BDBM226160 Ethyl 2-(6-chloro-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio)acetate (12)
BDBM325773 US9636339, 23 (rac)-Ethyl 2-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydroisoquinolin-8-yl]acetate
BDBM426839 US10544113, No. 68 Methyl {4-[2-(4-fluorophenyl)-4-oxo-1,3-thiazolidin-3-yl]-3-methylphenoxy}acetate
BDBM50173270 methyl 2-[1'-cyclododecylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL370782
BDBM50184038 CHEMBL206927 methyl 2-(2-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)picolinamido)acetate
BDBM50191133 sodium (R)-2-(3-((2-(4,5-diphenyloxazol-2-yl)pyrrolidin-1-yl)methyl)phenoxy)acetate CHEMBL439357
BDBM50193604 CHEMBL214020 (E)-4-(3-(4-amino-2-propylquinolin-6-ylamino)-3-oxoprop-1-enyl)phenyl acetate
BDBM50221687 CHEMBL392116 2-(1,3-dimethyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[1,2-a]purin-9(6H)-yl)-1-phenylethyl acetate
BDBM50224122 ethyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methoxy)phenyl]-1H-pyrrol-3-acetate CHEMBL398382
BDBM50224124 ethyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[4-(methoxy)phenyl]-1H-pyrrol-3-acetate CHEMBL237813
BDBM50224126 CHEMBL398383 Ehyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetate
BDBM50226640 CHEMBL400428 phenylmethyl 2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate
BDBM50235096 methyl 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-5-(quinolin-2-ylmethoxy)phenoxy)acetate CHEMBL255011
BDBM50263039 CHEMBL514365 tert-Butyl [8-carbamoyl-7-(3,5-dimethoxyphenylamino)-1,2,4-triazolo[4,3-c]pyrimidin-5-ylamino]acetate
BDBM50263445 ethyl 2-cyano-2-(3-ethyl-5-((2-fluorophenylamino)methylene)-4-oxothiazolidin-2-ylidene)acetate CHEMBL476137
BDBM50263587 propyl 2-cyano-2-(3-ethyl-5-((4-hydroxyphenylamino)methylene)-4-oxothiazolidin-2-ylidene)acetate CHEMBL477615
BDBM50263874 ethyl 2-(5-methyl-7-oxo-3-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)acetate CHEMBL1608283
BDBM50271143 (3R,4R)-(-)-6-methoxy-1-oxo-3-pentyl-3,4-dihydro-1H-isochromen-4-yl acetate CHEMBL529220
BDBM50296145 ethyl 2-(6-bromo-2-(4-fluorophenyl)-4-phenyl-1,2-dihydroquinazolin-3(4H)-yl)acetate CHEMBL555341
BDBM50316382 Ethyl-2-((S)-3-((S)-2-amino-3-methylbutanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride CHEMBL1095918
BDBM50316383 CHEMBL1097230 Ethyl-2-((S)-3-((S)-2-amino-4-methylpentanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride
BDBM50336425 2-methoxy-4-((2-(naphthalen-2-yl)-5-oxooxazol-4(5H)-ylidene)methyl)phenyl acetate CHEMBL1668292
BDBM50341272 (Z)-Methyl-2-(4-(5-(4-methoxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)phenoxy)acetate CHEMBL1765902
CHEMBL1085975 BDBM50320052 ethyl 2-(4-(benzyloxy)-3-((S)-3-cyclohexyl-2-(4-methylbenzamido)propanamido)-2-oxobutanamido)acetate
CHEMBL1085976 ethyl 2-(4-(benzyloxy)-3-((S)-3-cyclohexyl-2-(2,3-difluorobenzamido)propanamido)-2-oxobutanamido)acetate BDBM50320053
CHEMBL1095500 BDBM50316987 3,3-Dimethylbutyl 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
CHEMBL1254438 BDBM50327140 (R)-methyl 2-(4-(hydroxymethoxy)-3-(hydroxymethyl)phenyl)-2-((R)-1-methylpiperidin-2-yl)acetate
CHEMBL148629 BDBM22979 methyl 2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}formamido)acetate Meclofenamic acid derivative, 31
CHEMBL1683479 BDBM50337759 ethyl 2-(3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)thiazolidine-2-carboxamido)acetate hydrochloride
CHEMBL1766544 Ethyl 2-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)acetate BDBM50341648
CHEMBL198099 methyl 2-[1'-cyclohexylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173261
CHEMBL237402 phenylmethyl 2-{4-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate BDBM50226658
CHEMBL237626 ethyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(fluoro)-phenyl]-1H-pyrrol-3-acetate BDBM50224129
CHEMBL239016 2-(1,3-dimethyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[1,2-a]purin-9(6H)-yl)-1-phenylpropyl acetate BDBM50221689
CHEMBL241103 BDBM50206178 (E)-6-((3,4-dihydroisoquinolin-2(1H)-yl)methyleneamino)-2,3-dihydro-1H-inden-1-yl acetate
CHEMBL256765 methyl 2-(3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-2-ylmethoxy)phenoxy)acetate BDBM50235118
CHEMBL404266 methyl 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-2-ylmethoxy)phenoxy)acetate BDBM50235094
CHEMBL427010 methyl 2-[1'-cycloheptylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173284
CHEMBL434944 methyl 2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173254
CHEMBL438092 sodium (S)-2-(3-((2-(4,5-diphenyloxazol-2-yl)pyrrolidin-1-yl)methyl)phenoxy)acetate BDBM50191132
CHEMBL571219 BDBM50301055 4-(3-(2,4-dimethoxy-5-(2-methylbut-3-en-2-yl)phenyl)acryloyl)phenyl acetate
CHEMBL589812 Isopropyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetate BDBM50308734
CHEMBL589813 BDBM50308738 Isopropyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetate
Ethyl 2-(4-((2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl)amino)phenyl)acetate US11401286, Example 185 BDBM562613
Ethyl 2-(6,7-dimethoxy-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio)acetate (13) BDBM226161
Ethyl-2-((S)-2,6-dioxo-3-((S)-pyrrolidine-2-carboxamido)piperidin-1-yl)acetate hydrochloride BDBM50316391 CHEMBL1096255
Isopropyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methoxy)phenyl]-1H-pyrrol-3-acetate CHEMBL600167 BDBM50308740
US11220486, Compound I258 3-{4-[(3-piperidylpropyl)amino]-2- quinolyl]phenyl)methyl acetate US11220486, Compound I79 BDBM533149
US11401286, Example 208 BDBM562636 Methyl 2-(4-((2-(3-chlorophenyl)-6-cyclopropylpyrimidin-4-yl)methyl)phenyl)acetate
ethyl 2-{4-[2-(naphthalene-1-amido)-4-phenylphenyl]piperazin-1-yl}acetate BDBM16731 Naphthyl Compound, 5b
ethyl-2-Methyl-1-[4-(methylsulfonyl)phenyl]-5-[4-(fluoro)-phenyl]-1H-pyrrol-3-acetate BDBM50224113 CHEMBL237811
ethyl-2-Methyl-1-[4-(methylsulfonyl)phenyl]-5-[4-(trifluoro)phenyl]-1H-pyrrol-3-acetate CHEMBL238033 BDBM50224115
ethyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[4-(methyl)phenyl]-1H-pyrrol-3-acetate CHEMBL398384 BDBM50224127
ethyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetate CHEMBL238027 BDBM50224128
ethyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetate BDBM50224118 CHEMBL237592
methyl 2-(4-(3-(6-acetyl-5-hydroxy-4-propylpyridin-3-yloxy)propoxy)phenoxy)acetate CHEMBL212993 BDBM50189968
methyl 2-[1'-hexyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL198167 BDBM50173263
sodium-2-(3-((5-oxo-3,4-diphenyl-1H-pyrrol-2(5H)-ylidene)methyl)phenoxy)acetate CHEMBL603204 BDBM50305683
(+)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2 cyclopropylacetamido] acetate (Compound 20) BDBM115175 (−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2 cyclopropylacetamido] acetate (Compound 21)
methyl 2-(5-((2-acetamidothiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetate BDBM50205070 methyl{[4-(benzoylamino)-5-({2-[(acetyl)amino]-1,3-thiazol-4-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate CHEMBL232522
methyl{[4-(benzoylamino)-5-({2-[(benzoyl)amino]-1,3-thiazol-4-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate methyl 2-(5-((2-benzamidothiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetate CHEMBL399387 BDBM50205039
1-(2-bromo-4-chloro-phenyl)sulfonylpiperidine 1-[(2-bromo-4-chlorophenyl)sulfonyl]piperidine MLS000028544 BDBM44576 DEXAMETHASONE 21-ACETATE MLS000060983 SMR000058327 1-(2-bromo-4-chlorophenyl)sulfonylpiperidine DEXAMETHASONE ACETATE cid_772156 SMR000069748 cid_236702 1-(2-bromanyl-4-chloranyl-phenyl)sulfonylpiperidine
BDBM75034 SMR000338123 methyl 2-[4,5-dimethoxy-2-(methylsulfamoyl)phenyl]acetate cid_3365444 2-[4,5-dimethoxy-2-(methylsulfamoyl)phenyl]acetic acid methyl ester methyl 2-[4,5-dimethoxy-2-(methylsulfamoyl)phenyl]ethanoate methyl 2-{4,5-dimethoxy-2-[(methylamino)sulfonyl]phenyl}acetate MLS000755263
SMR000476349 MLS001179149 cid_878744 BDBM69626 acetic acid (3-benzoylbenzofuran-5-yl) ester acetic acid (3-benzoyl-5-benzofuranyl) ester (3-benzoyl-1-benzofuran-5-yl) acetate 3-benzoyl-1-benzofuran-5-yl acetate [3-(phenylcarbonyl)-1-benzofuran-5-yl] ethanoate
methyl 2-(4-benzamido-5-((2-(2-chloroacetamido)thiazol-4-yl)methyl)-4H-1,2,4-triazol-3-ylthio)acetate BDBM50205043 CHEMBL244081 methyl{[4-(benzoylamino)-5-({2-[(chloroacetyl)amino]-1,3-thiazol-4-yl}methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate
(R)-methyl 2- (2-chlorophenyl)-2- (5H-chromeno [3,4-c]pyridine-8- carboxamido)acetate US9914740, II-15 BDBM376299
(Z)-methyl 2-(5-methyl-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate CHEMBL1269381 BDBM50329082
(Z)-methyl 2-(7-nitro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate CHEMBL1269432 BDBM50329091
17-cyclopropylmethyl-16-methyl-13-methylcarbonyloxy-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaen-4-yl acetate BDBM50122526
BDBM12416 copper(2+) ion 2-[(carboxylatomethyl)({[(3-{[2-(4-sulfamoylphenyl)ethyl]carbamoyl}phenyl)carbamoyl]methyl})amino]acetate BR22
BDBM261670 US9708279, 47 isopropyl 2-((4-((4-(3-((triisopropylsilyl)ethynyl)phenyl)thiazol-2-yl)carbamoyl)benzyl)amino)acetate
BDBM327226 ethyl {[4-chloro-2-({[4-chloro-3-(trifluoromethyl)phenyl]sulfonyl}amino)phenyl]-sulfinyl}acetate US9663460, Example 13
BDBM357839 Step 1: Preparation of 5-bromo-6-chloro-3-(p-tolylethynyl)pyridin-2-yl acetate US10214534, Compound 6002
BDBM377975 US10266526, Compound 104 ethyl 2-(1-(L-alanyl)piperidin-4-yl)-2-(2-oxoindoline-5-carboxamido)acetate
BDBM411200 US10385022, Example 196 Methyl 2-(N-(4-(2-fluorophenyl)pyridin-3-yl)-2,6-bis(trifluoromethyl)isonicotinamido)acetate
BDBM50084106 Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phenyl-hept-1-enyl)-cyclohexyl]-acetate CHEMBL77513
BDBM50087681 CHEMBL164721 Sodium; {3-[(E)-7-(4-azido-phenyl)-3-hydroxy-hept-1-enyl]-1-hydroxy-cyclohexyl}-acetate
BDBM50173260 methyl 2-[1'-(4-methoxycyclohexylcarbonyl)-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL440038
BDBM50173271 methyl 2-[1'-(2-naphthylmethyl)-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL444620
BDBM50173280 methyl 2-[1'-(1-naphthylmethyl)-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL198678
BDBM50173282 methyl 2-[1'-(2-butyloctyl)-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL382086
BDBM50192125 CHEMBL385052 methyl 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)acetate
BDBM50205050 CHEMBL391674 methyl 2-(4-acetamido-5-((2-benzamidothiazol-4-yl)methyl)-4H-1,2,4-triazol-3-ylthio)acetate
BDBM50205509 (R,R)-(+)-ethyl {4-[2-{[2-(3-bromoisoxazol-5-yl)-2-hydroxyethyl]amino}propyl]phenoxy} acetate CHEMBL226348
BDBM50209248 (S)-ethyl 2-(1-(naphthalen-2-ylsulfonyl)-N-(1-phenethylpiperidin-4-yl)pyrrolidine-2-carboxamido)acetate CHEMBL428224
BDBM50308739 CHEMBL589087 n-Butyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetate
BDBM50316384 Ethyl-2-((S)-3-((2S,3R)-2-amino-3-methylpentanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride CHEMBL1097593
BDBM50320057 CHEMBL1083620 ethyl 2-(4-(benzyloxy)-3-((S)-2-(5-bromofuran-2-carboxamido)-3-cyclohexylpropanamido)-2-oxobutanamido)acetate
BDBM50329086 CHEMBL1269409 (Z)-methyl 2-(6-nitro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate
BDBM50329087 (Z)-methyl 2-(6-(ethylsulfonyl)-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate CHEMBL1270877
BDBM50329088 CHEMBL1269410 (Z)-methyl 2-(7-methyl-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate
BDBM50329089 (Z)-methyl 2-(7-fluoro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate CHEMBL1269430
BDBM50331083 CHEMBL1290362 ethyl 2-(3-methyl-7-(3-methylbenzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylthio)acetate
BDBM50341271 (Z)-Methyl-2-(4-((4-oxo-2-(p-tolyl)-4H-thiazol-5-ylidene)methyl)phenoxy)acetate CHEMBL1765901
BDBM526330 ethyl 2-(4-(2-((4- (trifluoromethyl)phenyl)amino)phenyl)-1H- pyrazol-1-yl)acetate US11186554, Compound 60
BDBM526419 ethyl 2-(4-(2-((4- (trifluoromethyl)phenyl)amino)phenyl)-1H- imidazol-1-yl)acetate US11186554, Compound 202
Benzthiazole compound, 33o [(1-{[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl}piperidin-4-yl)carbamoyl]methyl acetate BDBM24237
CHEMBL1085977 ethyl 2-((S)-4-(benzyloxy)-3-((S)-3-cyclohexyl-2-(2,5-difluorobenzamido)propanamido)-2-oxobutanamido)acetate BDBM50320054
CHEMBL1095501 BDBM50316986 2-(Trimethylsilyl)ethyl 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
CHEMBL1269382 BDBM50329083 (Z)-methyl 2-(6-methyl-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate
CHEMBL1269407 BDBM50329084 (Z)-methyl 2-(6-fluoro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate
CHEMBL1269408 BDBM50329085 (Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate
CHEMBL1269431 (Z)-methyl 2-(7-chloro-2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate BDBM50329090
CHEMBL232270 BDBM50204965 methyl 2-(4-acetamido-5-((2-acetamidothiazol-4-yl)methyl)-4H-1,2,4-triazol-3-ylthio)acetate
CHEMBL252843 3-(acetylthio)-4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formamido)pent-3-enyl acetate BDBM50230591
CHEMBL373222 BDBM50173248 methyl 2-[1'-(4-chlorobenzyl)-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate
CHEMBL387852 BDBM50205510 (S,R)-(-)-ethyl {4-[2-{[2-(3-bromoisoxazol-5-yl)-2-hydroxyethyl]amino}propyl]phenoxy} acetate
CHEMBL448790 BDBM50190426 methyl [3-chloro-4-(3-{[5-(1,2-dithiolan-3-yl)pentanoyl](methyl)amino}propoxy)phenyl]acetate
CHEMBL491398 methyl 2-(3-(4-bromophenyl)-7-oxo-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)acetate BDBM50263927
CHEMBL494514 BDBM50253311 N-{2-[(4-Carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}benzamide acetate
CHEMBL508974 (R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylacetamido)-5-oxopentylamino)(amino)methylene)ureido)acetate BDBM50246649
CHEMBL522486 Methyl 2-(4-(4-Fluorophenyl)-5-(2-(isopropylamino)pyridin-4-yl)-1H-imidazol-2-ylthio)acetate BDBM50253503
CHEMBL562831 BDBM50295994 ethyl 2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morpholinopyridin-2-ylamino)acetate
CHEMBL600844 BDBM50308737 n-Butyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetate
Ethyl 2-[1-methyl-6-[(1-methylcyclopropyl)sulfamoyl]-2,4-dioxo-quinazolin-3-yl]acetate BDBM371360 US10239843, Example 468
Ethyl 2-[2-(2-benzyl-5,6-dichloro-1H-benzo[d]imidazol-1-yl)pentanamido] acetate (Compound 9) BDBM115164
Ethyl-2-((S)-3-((S)-2-amino-3-phenylpropan amido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride CHEMBL1098915 BDBM50316385
Trifluoro-acetate(S)-1-((1S,2S)-1-cyano-2-phenyl-cyclopropylcarbamoyl)-2-(2-fluoro-phenyl)-ethyl-ammonium BDBM50269858
US11186554, Compound 76 ethyl 2-[3-methyl-4-[2-[4- (trifluoromethyl)anilino]phenyl]pyrazol-1- yl]acetate BDBM526336
US11401286, Example 203 BDBM562631 Methyl 2-(4-((2-(3-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4-yl)methyl)phenyl)acetate
[2-[(5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]methoxy]methyl acetate (14a) BDBM234288
ethyl 2-(4-((4-methyl-2-propyl-1H-benzo[d]imidazol-1-yl)methyl)phenoxy)acetate BDBM50303983 CHEMBL565793
ethyl 2-(4-(2-((3- (trifluoromethyl)phenyl)amino)phenyl)-1H- pyrazol-1-yl)acetate US11186554, Compound 58 BDBM526329
ethyl 2-[5-methyl-4-[2-[4- (trifluoromethyl)anilino]phenyl]pyrazol-1- yl]acetate US11186554, Compound 77 BDBM526337
ethyl {7-[(cyclohexylamino)carbonyl]-1-oxo-1,6,7,7a-tetrahydro-3a,6-epoxyisoindol-2-yl}acetate cid_3237886 MLS000092025 BDBM62672 SMR000026549
methyl 2-(4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bicyclo[2.2.1]heptan-2-yl)phenoxy)acetate BDBM50235113 CHEMBL258215
methyl-2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindolin-3-yl)acetate BDBM50344860 CHEMBL1780052
n-Butyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methoxy)phenyl]-1H-pyrrol-3-acetate CHEMBL589166 BDBM50308741
BDBM50205071 CHEMBL232320 methyl 2-(5-((2-(2-chloroacetamido)thiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)acetate methyl{[4-(benzoylamino)-5-({2-[(2-chloroacetyl)amino]-1,3-thiazol-4-yl} methyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetate
Dimethyl 2,2 -Dithiobis(1-methyl-1H-indole-3-acetate) methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1-methyl-1H-indol-2-yl]disulfanyl}-1-methyl-1H-indol-3-yl)acetate dithiobis(1H-indole-3-alkanoic acid) deriv. 23 BDBM3975
Dimethyl 2,2 -Thiobis(1-methyl-1H-indole-3-acetate) dithiobis(1H-indole-3-alkanoic acid) deriv. 24 BDBM3976 methyl 2-(2-{[3-(2-methoxy-2-oxoethyl)-1-methyl-1H-indol-2-yl]sulfanyl}-1-methyl-1H-indol-3-yl)acetate
methyl 2-[4-[(2-methylsulfanylphenyl)sulfamoyl]phenoxy]acetate MLS000097217 methyl [4-({[2-(methylthio)phenyl]amino}sulfonyl)phenoxy]acetate SMR000076824 2-[4-[[2-(methylthio)phenyl]sulfamoyl]phenoxy]acetic acid methyl ester methyl 2-[4-[(2-methylsulfanylphenyl)sulfamoyl]phenoxy]ethanoate cid_2208882 BDBM55301
(+/-)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulfonyl)-phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate BDBM50253566 CHEMBL522166
(+/-)-Ethyl-[2-hydroxy-2-[2-methyl-5-(4-methylsulfonyl)-phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate CHEMBL523720 BDBM50253352
(1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8k) BDBM167925
(1-(2-Fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8h) BDBM167922
(1-(2-Nitrobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8n) BDBM167928
(1-(3-Fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8i) BDBM167923
(1-(4-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8m) BDBM167927
(1-(4-Fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8j) BDBM167924
(1-(4-Methylbenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8g) BDBM167921
(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl 2-((2-oxo-2H-chromen-4-yl)oxy)acetate (8p) BDBM167930
(E)-6-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyleneamino)-2,3-dihydro-1H-inden-1-yl acetate BDBM50206174 CHEMBL241102
2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylamino)-2-oxoethyl 2-(4,6-diphenylpyrimidin-2-ylthio)acetate BDBM50346136 CHEMBL1782320
BDBM115167 Ethyl 2-[2-(2-benzyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)-2-cyclopropylacetamido] acetate (Compound 12)
BDBM115178 (−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-benzo[d]imidazol-1-yl)pentanamido]acetate (Compound 23)
BDBM14609 N-pyrazinylurea Analog 8d [(2-chloro-4-{[(5-cyanopyrazin-2-yl)carbamoyl]amino}-5-methoxyphenyl)carbamoyl]methyl acetate
BDBM167915 (1-(2-Bromobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8a)
BDBM167916 (1-(3-Bromobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8b)
BDBM167917 (1-(4-Bromobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8c)
BDBM167918 (1-(3-Methoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8d)
BDBM167919 (1-(4-Methoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8e)
BDBM167920 (1-(2-Methylbenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8f)
BDBM167929 (1-(4-Nitrobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8o)
BDBM312594 US9604989, Example 80 Methyl ({2-[4-(1-aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazin-6-yl}oxy)acetate
BDBM355315 US9815796, Example 406 methyl {[(6-oxo-2-phenyl-1,6- dihydropyrimidin-4- yl)carbonyl]amino}[4- (trifluoromethyl)phenyl]acetate
BDBM391966 Ethyl [2-({[(4- Bromophenyl)carbamoyl] amino}methyl)-1H- imidazol-1-yl]acetate US10301269, Number 11 US10800744, Number 11
BDBM432531 US10577363, Compound 231 ethyl 2-(((2S,4S)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate
BDBM432552 US10577363, Compound 252 ethyl 2-(((2R,4R)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate
BDBM432620 ethyl 2-(((2R,4S)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate US10577363, Compound 320
BDBM50106088 CHEMBL99888 Lithium; (R)-((S)-5-methyl-3-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetylamino}-hexanoylamino)-phenyl-acetate
BDBM50173249 methyl 2-[2-oxo-1'-(4-trifluoromethylbenzyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate CHEMBL197880
BDBM50183976 CHEMBL207232 methyl 2-(2-(3-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)acetamido)acetate
BDBM50183987 methyl 2-(3-(3-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)propanamido)acetate CHEMBL382192
BDBM50219109 1-(4-(2,3-dichlorophenyl)piperazin-1-yl)-4-(4-(pyridin-2-yl)-benzamido)butan-2-yl acetate CHEMBL242434
BDBM50253500 CHEMBL492264 Methyl 2-(4-(4-Fluorophenyl)-5-(2-(1-phenylethylamino)pyridin-4-yl)-1H-imidazol-2-ylthio)acetate
BDBM50263693 ethyl 2-cyano-2-(3-ethyl-5-((4-(2-methoxyacetamido)phenylamino)methylene)-4-oxothiazolidin-2-ylidene)acetate CHEMBL516582
BDBM50266190 ethyl 2-(3,5-dioxo-4-(2-oxo-2-(piperidin-1-yl)ethyl)-1,2,4-thiadiazolidin-2-yl)acetate CHEMBL458210
BDBM50315262 Methyl{4-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate CHEMBL1089225
BDBM50315268 CHEMBL1093467 Ethyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate
BDBM50320056 ethyl 2-((S)-3-((S)-2-(2-amino-5-bromobenzamido)-3-cyclohexylpropanamido)-4-(benzyloxy)-2-oxobutanamido)acetate CHEMBL1085979
BDBM50320058 ethyl 2-(4-(benzyloxy)-3-((S)-3-cyclohexyl-2-(6-methylpyrazine-2-carboxamido)propanamido)-2-oxobutanamido)acetate CHEMBL1085980
BDBM50322731 cid_4437145 2-(2-chloro-5-(trifluoromethyl)phenylamino)-2-oxo-1-phenylethyl 2-(3-methyl-4-nitrobenzamido)acetate CHEMBL1171857
BDBM562639 Ethyl 2-(6-((2-(3-chlorophenyl)-6-cyclopropylpyrimidin-4-yl)amino)pyridin-3-yl)acetate US11401286, Example 211
CHEMBL1085974 BDBM50320051 ethyl 2-(4-(benzyloxy)-3-((S)-3-cyclohexyl-2-(3-methyl-2-nitrobenzamido)propanamido)-2-oxobutanamido)acetate
CHEMBL1089517 BDBM50315269 Methyl{3-[(6-amino-2-methoxyethoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate
CHEMBL1170660 BDBM50322266 rac-Benzyl [1-butyl-2,5-dioxo-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undec-3-yl]acetate hydrochloride
CHEMBL1170773 BDBM50321789 (R)-ethyl 2-(1-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran]-6'-yl)acetate
CHEMBL1288105 N4-(6-((6-amino-2-methyl-4-quinolinyl)amino)hexyl)-2-methyl-4,6-quinolinediamine acetate NSC-238146 BDBM50332200
CHEMBL372135 methyl 2-[2-oxo-1'-(1-phenylethyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173273
CHEMBL380580 methyl 2-[2-oxo-1'-perhydro-2-naphthalenylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173276
CHEMBL495726 (S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-3-phenylpropan-2-yl acetate BDBM50265360
CHEMBL578414 BDBM50301050 4-(3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)acryloyl)phenyl acetate
CHEMBL583456 BDBM50301051 4-(3-(4-acetoxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)acryloyl)phenyl acetate
Ethyl-2-((S)-3-((S)-2-amino-3-(4-hydroxyphenyl)-propanamido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride BDBM50316389 CHEMBL1095913
Ethyl-2-((S)-3-((S)-2-amino-4-(methylthio)butan amido)-2,6-dioxopiperidin-1-yl)acetate hydrochloride CHEMBL1099253 BDBM50316387
Methyl 2-((1S,2R)-2-(5-carbamoyl-4-(m-tolylamino)pyrimidin-2-ylamino)cyclohexylamino)acetate US9579320, Example 203 BDBM290803
Methyl{2-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate BDBM50315261 CHEMBL1089220
Methyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate BDBM50315256 CHEMBL1089224
N-(Ethoxycarbonylmethyl)-maleimide ethyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate Maleimide-Related Compound 4 BDBM7805
Pirinixic acid-based compound, 2c ethyl 2-{[4-chloro-6-(quinolin-6-ylamino)pyrimidin-2-yl]sulfanyl}acetate BDBM24554
Sodium; [4-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-ylmethyl)-phenyl]-acetate (2.5H2O) BDBM50087376 CHEMBL39456
Step 1: Preparation of 5-bromo-6-chloro-3-((4-chlorophenyl)ethynyl)pyridin-2-yl acetate US10214534, Compound 4002 BDBM357836
US10285989, Example 205 BDBM384985 methyl ({[2-(dimethylamino)-6- oxo-1,6-dihydropyrimidin-4- yl]carbonyl}amino)[4- (trifluoromethyl)phenyl]acetate
US10975084, Example 8-7 methyl (5-methyl-7-oxo-4,7- dihydro[1,2,4]triazolo[1,5- a]pyrimidin-6-yl)acetate BDBM492405
[(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-yl)carbamoyl]methyl acetate Benzthiazole compound, 27o BDBM24230
[(20S)-20-(N,N-dimethylamino)-3 beta-(senecioylamino)-5 alpha-pregn-16-en-4 beta-yl acetate] CHEMBL460447 BDBM50242345
ethyl 2-(((2S,4R)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate BDBM432545 US10577363, Compound 245
methyl 2-(2-(methyl(5-(pyrrolidin-1-yl)pentyl)amino)-3-phenyl-3,4-dihydroquinazolin-4-yl)acetate BDBM50197239 CHEMBL245610
methyl 2-[2-oxo-1'-(3-trifluoromethylbenzyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173266 CHEMBL264066
methyl 2-[2-oxo-1'-(4-phenylbenzyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate BDBM50173278 CHEMBL198322
(E)-methyl 2-(4-(1H-indol-3-yl)piperidin-1-yl)-2-(1-(3-(3,4,5-trifluorophenyl)acryloyl)piperidin-4-yl)acetate CHEMBL392366 BDBM50224509 methyl 2-(4-(1H-indol-3-yl)piperidin-1-yl)-2-(1-(3-(3,4,5-trifluorophenyl)acryloyl)piperidin-4-yl)acetate
4-{[(acetylamino)carbonyl]amino}tetrahydro-3-thienyl acetate SMR000069129 [4-(ethanoylcarbamoylamino)thiolan-3-yl] ethanoate acetic acid [4-[[acetamido(oxo)methyl]amino]-3-thiolanyl] ester [4-(acetylcarbamoylamino)thiolan-3-yl] acetate cid_2832895 MLS000060901 acetic acid [4-(acetylcarbamoylamino)tetrahydrothiophen-3-yl] ester BDBM40890
CHEMBL100958 BDBM50119344 (S)-methyl 2-cyclohexyl-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)acetate methyl 2-cyclohexyl-2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyridinylmethyl]-4-phenyltetrahydro-1H-1-pyrrolyl}acetate
MLS000048242 methyl {4-[(1,3-benzodioxol-5-ylamino)sulfonyl]phenoxy}acetate methyl 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]acetate cid_1082971 BDBM40052 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]acetic acid methyl ester methyl 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]ethanoate SMR000073539
[4-[(2-phenylsulfanylacetyl)amino]phenyl] acetate SMR000072806 acetic acid [4-[[1-oxo-2-(phenylthio)ethyl]amino]phenyl] ester acetic acid [4-[[2-(phenylthio)acetyl]amino]phenyl] ester 4-{[2-(phenylthio)acetyl]amino}phenyl acetate MLS000063417 cid_891318 BDBM50044 [4-(2-phenylsulfanylethanoylamino)phenyl] ethanoate
cid_1005954 ethyl 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]ethanoate ethyl {4-[(1,3-benzodioxol-5-ylamino)sulfonyl]phenoxy}acetate SMR000073906 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]acetic acid ethyl ester BDBM41339 MLS000096682 ethyl 2-[4-(1,3-benzodioxol-5-ylsulfamoyl)phenoxy]acetate
(+)-(S)-Ethyl-[2-hydroxy-2-[2-methyl-5-(4-methylsulfonyl)phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate BDBM50253487 CHEMBL494700
BDBM50253312 CHEMBL494715 Ethyl 4-{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino}-4-oxobutanoate acetate
BDBM50253488 CHEMBL494904 (-)-(R)-Ethyl-[2-hydroxy-2-[2-methyl-5-(4-methylsulfonyl)phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate
BDBM50253567 (+)-(S)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulfonyl)phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate CHEMBL493492
BDBM50253568 CHEMBL523515 (-)-(R)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulfonyl)phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate
BDBM50343394 methyl 2-(2-(4-fluorophenyl)-8-methyl-4H-benzo[b]imidazo[1,2-d][1,4]oxazin-4-yl)acetate CHEMBL1774935
CHEMBL459318 Ethyl 2-(N-{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}benzamido)acetate BDBM50253932
CHEMBL517875 BDBM50253780 Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl}amino)acetate
Ethyl 2-(benzyl{2-[(4-carbamimidoylphenoxy)methyl]-2,4-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-6-yl}amino)acetate BDBM50253816 CHEMBL460143
US9579320, Example 187 tert-butyl 2-(3-(2-((1R,2S)-2-aminocyclohexylamino)-5-carbamoylpyrimidin-4-ylamino)phenoxy)acetate (Racemate) BDBM290788
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- Loe, DW; Almquist, KC; Cole, SP; Deeley, RG ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. J Biol Chem 271: 9683-9 (1996)
- Maltais, R; Trottier, A; Delhomme, A; Barbeau, X; Lagüe, P; Poirier, D Identification of fused 16ß,17ß-oxazinone-estradiol derivatives as a new family of non-estrogenic 17ß-hydroxysteroid dehydrogenase type 1 inhibitors. Eur J Med Chem 93: 470-80 (2015)
- Maltais, R; Ayan, D; Trottier, A; Barbeau, X; Lagüe, P; Bouchard, JE; Poirier, D Discovery of a non-estrogenic irreversible inhibitor of 17?-hydroxysteroid dehydrogenase type 1 from 3-substituted-16?-(m-carbamoylbenzyl)-estradiol derivatives. J Med Chem 57: 204-22 (2014)
- Burkhart, JP; Koehl, JR; Mehdi, S; Durham, SL; Janusz, MJ; Huber, EW; Angelastro, MR; Sunder, S; Metz, WA; Shum, PW Inhibition of human neutrophil elastase. 3. An orally active enol acetate prodrug. J Med Chem 38: 223-33 (1995)
- Sugiyama, D; Kusuhara, H; Shitara, Y; Abe, T; Sugiyama, Y Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates. Drug Metab Dispos 30: 220-3 (2002)
- Laplante, Y; Cadot, C; Fournier, MA; Poirier, D Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone. Bioorg Med Chem 16: 1849-60 (2008)
- Lobaccaro, C; Pons, JF; Duchesne, MJ; Auzou, G; Pons, M; Nique, F; Teutsch, G; Borgna, JL Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties. J Med Chem 40: 2217-27 (1997)
- Ouellet, E; Ayan, D; Poirier, D Synthesis and preliminary evaluation of a modified estradiol-core bearing a fused¿-lactone as non-estrogenic inhibitor of 17ß-hydroxysteroid dehydrogenase type 1. Bioorg Med Chem Lett 21: 5510-3 (2011)
- Cushman, M; He, HM; Katzenellenbogen, JA; Lin, CM; Hamel, E Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site. J Med Chem 38: 2041-9 (1995)
- Smith, ME; Gunn, RM; Rosivatz, E; Mak, LH; Woscholski, R; Hailes, HC Development of chemical probes: toward the mode of action of a methylene-linked di(aryl acetate) E1. Bioorg Med Chem 18: 4917-27 (2010)
- Innocenti, A; Supuran, CT Paraoxon, 4-nitrophenyl phosphate and acetate are substrates ofa- but not ofß-,¿- and¿-carbonic anhydrases. Bioorg Med Chem Lett 20: 6208-12 (2010)
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- Whitehead, L; Dobler, MR; Radetich, B; Zhu, Y; Atadja, PW; Claiborne, T; Grob, JE; McRiner, A; Pancost, MR; Patnaik, A; Shao, W; Shultz, M; Tichkule, R; Tommasi, RA; Vash, B; Wang, P; Stams, T Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. Bioorg Med Chem 19: 4626-34 (2011)
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- ChEMBL_1358461 Displacement of radiolabeled estradiol from estradiol receptor in rat uterine cytosol
- ChEMBL_515889 (CHEMBL630846) Displacement of [3H]estradiol from full-length human estrogen receptor beta by radiometric assay relative to estradiol
- ChEMBL_838505 (CHEMBL649958) TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cells
- ChEMBL_66548 (CHEMBL620432) Inhibition of estradiol binding to estrogen receptor
- ChEMBL_879294 (CHEMBL689613) Inhibition of human estradiol 17beta-dehydrogenase
- ChEBML_67517 Displacement of [3H]estradiol from Estrogen receptor alpha
- ChEBML_67826 Displacement of [3H]estradiol from Estrogen receptor beta
- ChEMBL_331401 (CHEMBL645646) Displacement of [3H]17beta-estradiol from ERalpha
- ChEMBL_331402 (CHEMBL644545) Displacement of [3H]17beta-estradiol from ERbeta
- ChEMBL_381820 (CHEMBL691293) Displacement of [3H]estradiol from human ERalpha
- ChEMBL_381821 (CHEMBL691294) Displacement of [3H]estradiol from human ERbeta
- ChEMBL_398763 (CHEMBL708890) Inhibition of estradiol to estrone conversion in MG63 cells
- ChEMBL_526667 (CHEMBL644282) Displacement of [3H]estradiol from estrogen receptor
- ChEMBL_815206 (CHEMBL629838) Displacement of [3H]-17beta-estradiol from ERalpha
- ChEMBL_815207 (CHEMBL630468) Displacement of [3H]-17beta-estradiol from ERbeta
- ChEBML_67369 Displacement of [3H]estradiol from human estrogen receptor alpha
- ChEMBL_207426 (CHEMBL621564) Inhibition of estradiol-stimulated T-47D cell proliferation.
- ChEMBL_438780 (CHEMBL653154) Displacement of [3H]estradiol from human recombinant ERalpha
- ChEMBL_438781 (CHEMBL653155) Displacement of [3H]estradiol from human recombinant ERbeta
- ChEMBL_504921 (CHEMBL618944) Displacement of [3H]estradiol from human recombinant ERalpha
- ChEMBL_509492 (CHEMBL625362) Displacement of [3H]estradiol from human recombinant ERbeta
- ChEMBL_65909 (CHEMBL618619) Binding affinity for estrogen receptor, by competition with [3H]estradiol
- ChEMBL_65914 (CHEMBL618624) Displacement of [3H]-estradiol from estrogen receptor (ER)
- ChEMBL_67517 (CHEMBL624405) Displacement of [3H]estradiol from Estrogen receptor alpha
- ChEMBL_67826 (CHEMBL620216) Displacement of [3H]estradiol from Estrogen receptor beta
- ChEBML_67502 Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alpha
- ChEBML_67827 Inhibition of binding of 17 beta-estradiol to human Estrogen receptor beta
- ChEMBL_1282735 Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assay
- ChEMBL_172928 (CHEMBL683396) Displacement of [3H]estradiol from estrogen receptor in immature rat
- ChEMBL_1744049 (CHEMBL1768199) Displacement of estradiol from human ERalpha expressed in yeast cells
- ChEMBL_1744050 (CHEMBL1768200) Displacement of estradiol from human ERbetaa expressed in yeast cells
- ChEMBL_217747 (CHEMBL875236) Inhibition of estradiol-stimulated ZR-75-1-cell proliferation
- ChEMBL_217753 (CHEMBL629266) Inhibition of estradiol-stimulated ZR-75-1-cell proliferation
- ChEMBL_313633 (CHEMBL631016) pIC50 for 1 nM estradiol-induced Ishikawa cell proliferation
- ChEMBL_448344 (CHEMBL663333) Displacement of [3H]17beta-estradiol from recombinant human ERalpha
- ChEMBL_448345 (CHEMBL663334) Displacement of [3H]17beta-estradiol from recombinant human ERbeta
- ChEMBL_630247 (CHEMBL642900) Displacement of [3H]estradiol from human placental 17beta-HSD2
- ChEMBL_66378 (CHEMBL620217) Displacement of [3H]estradiol from estrogen receptor in squirrel monkey
- ChEMBL_66403 (CHEMBL875832) Displacement of [3H]estradiol from estrogen receptor in immature rabbit
- ChEMBL_66409 (CHEMBL623351) Displacement of [3H]estradiol from estrogen receptor in immature rabbit
- ChEMBL_66410 (CHEMBL623352) Displacement of [3H]estradiol from estrogen receptor in immature rat
- ChEMBL_66411 (CHEMBL623353) Displacement of [3H]estradiol from estrogen receptor in mature rat
- ChEMBL_66539 (CHEMBL623659) Displacement of [3H]-estradiol from estrogen receptor in immature rat
- ChEMBL_66540 (CHEMBL623660) Displacement of [3H]-estradiol from estrogen receptor in mature rat
- ChEMBL_66852 (CHEMBL623412) Displacement of [3H]estradiol from estrogen receptor in mature rat
- ChEMBL_66867 Displacement of [3H]-estradiol (E2) from sheep uterine estrogen receptor
- ChEMBL_68148 (CHEMBL621257) Displacement of [3H]estradiol from estrogen receptor in squirrel monkey
- ChEBML_67812 Displacement of [3H]17-beta-estradiol from human Estrogen receptor beta
- ChEMBL_1484215 (CHEMBL1001899) Inhibition of SULT1A1 in human MCF7 cells assessed as 17beta-estradiol sulfation
- ChEMBL_65915 (CHEMBL618625) Displacement of [3H]estradiol from Estrogen receptor in MCF-7 cells
- ChEMBL_66547 (CHEMBL621856) Displacement of [3H]- Estradiol from Estrogen receptor of rat uterine cytosol
- ChEMBL_66550 (CHEMBL620434) Displacement of [3H]- Estradiol from Estrogen receptor of rat uterine cytosol
- ChEMBL_66864 (CHEMBL623315) Irreversible inhibition of [3H]estradiol binding to lamb uterine estrogen receptor
- ChEMBL_67019 (CHEMBL624235) Displacement of [3H]estradiol from estrogen receptor-ligand binding domain
- ChEMBL_67037 (CHEMBL624252) Binding affinity for human estrogen receptor alpha by displacement of [3H]estradiol
- ChEMBL_67502 (CHEMBL624613) Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alpha
- ChEMBL_67520 (CHEMBL624408) Inhibition of binding of 17 beta-estradiol to human Estrogen receptor alpha
- ChEMBL_67821 (CHEMBL620211) Inhibition of binding of 17 beta-estradiol to human Estrogen receptor beta
- ChEMBL_67827 (CHEMBL620888) Inhibition of binding of 17 beta-estradiol to human Estrogen receptor beta
- ChEMBL_808084 (CHEMBL619443) Displacement of [3H]estradiol from rat uterine cytosolic estrogen receptor
- ChEMBL_99795 (CHEMBL625273) Inhibition of estradiol-stimulated MCF-7 breast adenocarcinoma cell proliferation
- ChEMBL_1577036 (CHEMBL1036327) Antagonist activity at ERalpha (unknown origin) transfected in 17beta-estradiol induced-HEK293 cells assessed as inhibition of estradiol-mediated protein transcriptional activity after 8 hrs by Luciferase reporter gene assay
- ChEBML_1581929 Displacement of [3H]-17beta-estradiol from human recombinant ERalpha expressed in rabbit reticulocytes
- ChEBML_1581930 Displacement of [3H]-17beta-estradiol from human recombinant ERbeta expressed in rabbit reticulocytes
- ChEBML_1664056 Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation counting
- ChEBML_67682 Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.
- ChEMBL_1770486 (CHEMBL1839189) Inhibition of UGT1A1 in human liver microsomes assessed as decrease in estradiol-3 glucuronidation
- ChEMBL_207428 (CHEMBL621566) Apparent binding affinity against estradiol-stimulated T-47D cell proliferation
- ChEMBL_220735 (CHEMBL633663) Relative binding affinity for human estrogen receptor alpha by displacement of [3H]-estradiol
- ChEMBL_305778 (CHEMBL623373) Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor beta
- ChEMBL_305813 (CHEMBL875835) Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha
- ChEMBL_320908 (CHEMBL636410) Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiol
- ChEMBL_320911 (CHEMBL857260) Antagonistic activity against estrogen receptor alpha in presence of 0.1 nM estradiol
- ChEMBL_468678 (CHEMBL682449) Displacement of [3H]estradiol from purified full length human ERalpha receptor
- ChEMBL_468679 (CHEMBL682450) Displacement of [3H]estradiol from purified full length human ERbeta receptor
- ChEMBL_552852 (CHEMBL664376) Inhibition of human placental 17beta-HSD2 using 17-beta-estradiol substrate
- ChEMBL_610117 (CHEMBL623743) Displacement of [3H]estradiol from human recombinant ERalpha by liquid scintillation counting
- ChEMBL_618687 (CHEMBL630513) Displacement of [3H]17beta-estradiol from human ERalpha expressed in SF9 cells
- ChEMBL_66542 (CHEMBL875281) In vitro displacement of [3H]estradiol from estrogen receptor of rat uterine cystol
- ChEMBL_66552 (CHEMBL620436) Equilibrium dissociation constant for rat uterine estrogen receptor binding [3H]estradiol
- ChEMBL_66868 (CHEMBL623319) Relative binding affinity for sheep uterine estrogen receptor by displacement of [3H]estradiol
- ChEMBL_67038 (CHEMBL624253) Relative binding affinity for human estrogen receptor alpha compared to [3H]estradiol
- ChEMBL_67200 (CHEMBL621393) Relative binding affinity for human estrogen receptor beta by displacement of [3H]estradiol
- ChEMBL_67202 (CHEMBL621395) Relative binding affinity for human estrogen receptor beta compared to [3H]-estradiol
- ChEMBL_67488 (CHEMBL624600) Displacement of [3H]17-beta-estradiol from human Estrogen receptor alpha
- ChEMBL_67508 (CHEMBL624396) Displacement of [3H]17-beta-estradiol from human estrogen receptor alpha
- ChEMBL_68140 (CHEMBL621077) Displacement of [3H]17-beta-estradiol from MCF-7 cell lysate
- ChEMBL_826711 (CHEMBL634878) Displacement of [3H]estradiol from ERalpha after 4 hrs by scintillation counting
- ChEMBL_826712 (CHEMBL634879) Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation counting
- ChEMBL_877515 (CHEMBL686490) Inhibition of 17beta-HSD1 assessed as conversion of estrone to estradiol by scintillation counting method
- ChEMBL_1476878 (CHEMBL940050) Antagonist activity at ER alpha in human MCF7 cells assessed as inhibition of estradiol-induced PR expression treated for 24 hrs after incubation with estradiol for 30 mins by laser scanning imaging cytometer analysis
- ChEBML_67363 Displacement of [3H]17-beta-estradiol from full length human estrogen receptor alpha
- ChEBML_67680 Displacement of [3H]17-beta-estradiol from full length human estrogen receptor beta
- ChEMBL_100276 (CHEMBL615716) Inhibition of estradiol induced estrogen receptor transcriptional activation in MCF-7-2a cells
- ChEMBL_1664056 (CHEMBL1261295) Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation counting
- ChEMBL_217754 (CHEMBL629267) Apparent binding affinity against estradiol-stimulated ZR-75-1-cell proliferation
- ChEMBL_306592 (CHEMBL621464) Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hr
- ChEMBL_306604 (CHEMBL618482) Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 20 hr
- ChEMBL_326622 (CHEMBL636691) Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cells
- ChEMBL_326623 (CHEMBL636692) Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cells
- ChEMBL_536779 (CHEMBL650300) Displacement of [3H]estradiol from human estrogen receptor alpha/estrogen receptor beta
- ChEMBL_544137 (CHEMBL653289) Inhibition of 17beta-HSD1 assessed as conversion of [14C]estradiol to [14C]estrone using NADP+
- ChEMBL_545688 (CHEMBL654763) Displacement of fluorescein-labeled estradiol from human recombinant ERalpha by fluorescence polarization assay
- ChEMBL_545689 (CHEMBL654764) Displacement of fluorescein-labeled estradiol from human recombinant ERbeta by fluorescence polarization assay
- ChEMBL_635744 (CHEMBL884027) Displacement of [3H]17-beta-estradiol from human recombinant full length ERalpha
- ChEMBL_635745 (CHEMBL648155) Displacement of [3H]17-beta-estradiol from human recombinant full length ERbeta
- ChEMBL_66071 (CHEMBL622639) Inhibition of estradiol binding to estrogen receptor in Human Breast cancer cytosol (3.3% ethanol)
- ChEMBL_66404 (CHEMBL623346) Displacement of [3H]17-beta-estradiol from Estrogen receptor of rabbit uterine tissue
- ChEMBL_66405 (CHEMBL623347) Displacement of [3H]17-beta-estradiol from Estrogen receptor of rabbit uterine tissue
- ChEMBL_67173 (CHEMBL621840) In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha
- ChEMBL_67365 (CHEMBL618590) Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.
- ChEMBL_67519 (CHEMBL624407) In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alpha
- ChEMBL_67682 (CHEMBL626139) Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.
- ChEBML_67512 Ability to displace [3H]17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.
- ChEBML_67823 Ability to displace [3H]17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.
- ChEMBL_100268 (CHEMBL615709) Agonist activity in transcriptional activation assay in MCF-7-2a cells compared to estradiol E2
- ChEMBL_101112 (CHEMBL616057) Inhibition of 17-beta-estradiol (10e-11 M) mediated MCF-7 cell proliferation
- ChEMBL_1487741 (CHEMBL1009473) Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using estradiol-17beta-glucuronide substrate
- ChEMBL_1519264 (CHEMBL946703) Antagonist activity at progesterone receptor in human MCF cells assessed as estradiol-induced receptor response
- ChEMBL_306408 (CHEMBL623350) Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coli
- ChEMBL_306421 (CHEMBL623362) Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coli
- ChEMBL_306448 (CHEMBL621167) Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coli
- ChEMBL_306464 (CHEMBL621181) Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coli
- ChEMBL_492828 (CHEMBL703134) Displacement of [3H]estradiol from ERalpha in rat uteri cytosol by competitive radiometric binding assay
- ChEMBL_514253 (CHEMBL626511) Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiol
- ChEMBL_514254 (CHEMBL626512) Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estrone
- ChEMBL_535112 (CHEMBL649314) Displacement of [3H]estradiol from full length biotinylated human ERalpha by scintillation proximity assay
- ChEMBL_535113 (CHEMBL649315) Displacement of [3H]estradiol from full length biotinylated human ERbeta by scintillation proximity assay
- ChEMBL_552857 (CHEMBL664381) Inhibition of 17-beta-HSD1-mediated 17-beta-estradiol formation in human T47D cells
- ChEMBL_65908 (CHEMBL618618) Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%
- ChEMBL_67363 (CHEMBL618588) Displacement of [3H]17-beta-estradiol from full length human estrogen receptor alpha
- ChEMBL_67680 (CHEMBL626137) Displacement of [3H]17-beta-estradiol from full length human estrogen receptor beta
- ChEMBL_815209 (CHEMBL630470) Displacement of [3H]-estradiol from human full length recombinant ERalpha by scintillation proximity assay
- ChEMBL_815210 (CHEMBL630471) Displacement of [3H]-estradiol from human full length recombinant ERbeta by scintillation proximity assay
- ChEMBL_88150 (CHEMBL621259) Stimulation of alkaline phosphatase activity in human endometrial Ishikawa cells with 1 nM E2 estradiol
- ChEMBL_88151 (CHEMBL621260) Stimulation of alkaline phosphatase activity in human endometrial Ishikawa cells with 1 nM E2 estradiol
- ChEBML_67500 In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor alpha expressed in 293T cells
- ChEBML_67820 In vitro concentration required to inhibit [3H]estradiol binding to human estrogen receptor beta expressed in 293T cells
- ChEMBL_103299 (CHEMBL619098) Anti-estrogenicity for 50% inhibition of the MVLN cell luciferase activity due to 0.1 nM E2 (estradiol)
- ChEMBL_1436369 (CHEMBL904677) Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using [3H]estradiol-17beta-glucuronide substrate
- ChEMBL_1436370 (CHEMBL904678) Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cells using [3H]estradiol-17beta-glucuronide substrate
- ChEMBL_1590441 (CHEMBL1055286) Inhibition of human 17-beta-HSD14 using estradiol as substrate after 15 mins by fluorimetric assay
- ChEMBL_1717009 (CHEMBL1671081) Antagonist activity at ER in human MCF7 cells assessed as inhibition of 17beta-estradiol-induced cell proliferation
- ChEMBL_1869284 Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estradiol-driven PR response by microplate cytometry
- ChEMBL_306229 (CHEMBL624231) Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coli
- ChEMBL_306245 (CHEMBL621686) Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coli
- ChEMBL_312915 (CHEMBL631001) Antagonist effect against 10 pM 17-beta-estradiol induced MCF-7 cell proliferation
- ChEMBL_492829 (CHEMBL703135) Displacement of [3H]estradiol from ERbeta receptor in rat uteri cytosol by competitive radiometric binding assay
- ChEMBL_536773 (CHEMBL650295) Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor by fluorescence polarization assay
- ChEMBL_544140 (CHEMBL653292) Inhibition of 17beta-HSD1 expressed in HEK 293 cells assessed as conversion of [14C]estrone to [14C]estradiol
- ChEMBL_67167 (CHEMBL621835) In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor alpha
- ChEMBL_67329 (CHEMBL621863) In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor beta
- ChEMBL_67341 (CHEMBL621245) In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2
- ChEMBL_751834 (CHEMBL664058) Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assay
- ChEMBL_752205 (CHEMBL664839) Inhibition of fluorescence-labeled 17beta-estradiol binding to ERalpha receptor after 2 hrs by fluorometric analysis
- ChEMBL_863171 (CHEMBL674398) Displacement of [3H]-estradiol from human recombinant ERalpha expressed in Sf21 cells after 2 hrs
- ChEMBL_863172 (CHEMBL678870) Displacement of [3H]-estradiol from human recombinant ERbeta expressed in Sf21 cells after 2 hrs
- Estrogen Receptor Binding Assay. The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determined by saturation binding to ER receptors. The IC50 values for compounds were converted to Ki using Cheng-Prusoff equation.
- ChEBML_68138 Tested by protection experiments to demonstrate the inactivation of estradiol dehydrogenase and the kinetic parameter Ki app was reported at a concentration of 20 uM
- ChEMBL_103159 (CHEMBL617804) Compound concentration required to induce transcriptional activation in MVLN cells comparable to 50% of 0.1 nM estradiol response
- ChEMBL_103160 (CHEMBL617805) Compound concentration required to induce transcriptional activation in MVLN cells equal to 50% of 0.1 nM estradiol response
- ChEMBL_1584556 (CHEMBL1054239) Inhibition of human placental microsomal aromatase using testosterone as substrate assessed as formation of estradiol after 10 mins
- ChEMBL_1649843 (CHEMBL1219541) Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assay
- ChEMBL_320910 (CHEMBL638361) Binding affinity towards human estrogen receptor beta in a competitive binding assay using fluorescently labelled estradiol
- ChEMBL_320912 (CHEMBL638362) Binding affinity towards human estrogen receptor alpha in a competitive binding assay using fluorescently labelled estradiol
- ChEMBL_508157 (CHEMBL621265) Inhibition of neutrophil elastase activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrs
- ChEMBL_508158 (CHEMBL621266) Inhibition of cathepsin G activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrs
- ChEMBL_508159 (CHEMBL621267) Inhibition of proteinase-3 activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrs
- ChEMBL_552334 (CHEMBL660443) Inhibition of human MRP2-mediated estradiol-17-beta-glucuronide transport in Sf9 cells inverted membrane vesicles
- ChEMBL_555024 (CHEMBL668939) Inhibition of human recombinant 17beta-HSD1 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol
- ChEMBL_555026 (CHEMBL668941) Inhibition of human recombinant 17beta-HSD2 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol
- ChEMBL_555345 (CHEMBL667973) Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiol
- ChEMBL_649075 (CHEMBL662305) Displacement of [3H]estradiol from human ERalpha ligand binding domain expressed in Escherichia coli BL21 (DE3)
- ChEMBL_67203 (CHEMBL621396) In vitro binding affinity towards human Estrogen receptor 2 using [3H]17-beta-estradiol as radioligand
- ChEMBL_67518 (CHEMBL624406) In vitro binding affinity towards human Estrogen receptor alpha using [3H]17-beta-estradiol as radioligand
- ChEMBL_684637 (CHEMBL695979) Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 mins
- ChEMBL_362836 (CHEMBL679957) Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysis
- ChEMBL_1345989 Displacement of [2,4,6,7-3H]-estradiol from estrogen receptor in immature rat uterine cytosol by dextran-coated charcoal-adsorption assay
- ChEMBL_1363487 Inhibition of human placental 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysis
- ChEMBL_1363489 Inhibition of human placental 17beta-HSD1 cytosolic fraction using tritiated estrone as substrate assessed as formation of estradiol by HPLC analysis
- ChEMBL_1363494 Inhibition of mouse liver 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysis
- ChEMBL_1934443 (CHEMBL2321162) Inhibition of full length human ERalpha expressed in human HEC1 cells in presence of estradiol by luciferase reporter gene assay
- ChEMBL_313068 (CHEMBL622307) Antagonist activity as inhibition of 1 nM 17-beta-estradiol stimulated alkaline phosphatase induction in Ishikawa endometrial cells
- ChEMBL_448350 (CHEMBL875703) Antagonist activity at ERalpha expressed in yeast AH109 assessed as inhibition of 17-beta-estradiol induced alpha-galactosidase activity
- ChEMBL_454488 (CHEMBL665491) Displacement of [3H]estradiol from full length human recombinant ERalpha after 3 hrs by scintillation proximity assay
- ChEMBL_454489 (CHEMBL665492) Displacement of [3H]estradiol from full length human recombinant ERbeta after 3 hrs by scintillation proximity assay
- ChEMBL_544139 (CHEMBL653291) Inhibition of 17beta-HSD1 expressed in HEK 293 cells assessed as conversion of [14C]estrone to [14C]estradiol using NADH
- ChEMBL_544141 (CHEMBL653293) Inhibition of 17beta-HSD1 expressed in HEK 293 cells assessed as conversion of [14C]estrone to [14C]estradiol using NADPH
- Estrogen Receptor Binding Assay. Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ER. Hydroxyapatite was used to adsorb the receptor-ligand complexes, and free ligand was washed away. The binding affinities are expressed as relative binding affinity (RBA) values with the RBA of estradiol set to 100%. The values given are the average +/- range or SD of two to three independent determinations. Estradiol binds to ERalpha with a Kd of 0.2 nM and to ERbeta with a Kd of 0.5 nM.
- ChEMBL_1484212 (CHEMBL1001896) Inhibition of human SULT1A1 expressed in Escherichia coli assessed as 17beta-estradiol sulfation at 100 nM by Michaelis-Menten equation analysis
- ChEMBL_1486476 (CHEMBL1014782) Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS method
- ChEMBL_1490069 (CHEMBL990900) Inhibition of OATP1B3-mediated [3H]estradiol 17beta-glucuronide uptake in human OATP1B3 expressing HEK293/PDZK1 cells by scintillation counting
- ChEMBL_1717005 (CHEMBL1671077) Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting method
- ChEMBL_2149318 (CHEMBL756353) Displacement of fluorescent estradiol from full-length ERalpha (unknown origin) measured after 2 hrs by fluorescence polarization assay
- ChEMBL_492826 (CHEMBL703132) Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarization assay
- ChEMBL_492827 (CHEMBL703133) Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarization assay
- ChEMBL_647642 (CHEMBL659913) Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation counting
- ChEMBL_67194 (CHEMBL621387) In vitro inhibition of 1 nM 17-beta-estradiol induced transcriptional activation in T47D cells expressing estrogen receptor beta
- ChEMBL_67501 (CHEMBL875167) In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor alpha
- ChEMBL_67516 (CHEMBL624404) Binding affinity for Estrogen receptor alpha of human breast cancer cells (MCF-7) by displacement of [3H]17-alpha-estradiol
- ChEMBL_841251 (CHEMBL654377) Displacement of fluorescent labelled PGC-1alpha from estradiol-ERalpha complex after 2 to 4 hrs by TR-FRET assay
- ChEMBL_841252 (CHEMBL654378) Displacement of fluorescent labelled PGC-1alpha from estradiol-ERbeta complex after 2 to 4 hrs by TR-FRET assay
- ChEBML_78556 Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.
- Estrogen Receptor Binding Assay and Ishikawa Assay The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determined by saturation binding to ER receptors. The IC50 values for compounds were converted to Ki using Cheng-Prusoff equation. Estrogenic stimulation and antagonism were measured in Ishikawa human endometrial tumor cells by alkaline phosphatase quantitation. The data were fitted to a linear interpolation to derive IC50 values for the antagonist mode and a percentage efficacy was calculated that blocks the 17beta-estradiol (1nM) stimulus.
- ChEMBL_1287642 Mixed-type inhibition of ER-alpha (unknown origin) expressed in ER-negative human SKBR3 cells coexpressing ERE using estradiol as substrate
- ChEMBL_1484074 (CHEMBL1005281) Inhibition of human OATP1B1 expressed in CHO cells using [3H]estradiol 17beta-D-glucuronide as substrate by liquid scintillation counting analysis
- ChEMBL_1580951 (CHEMBL1054916) Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunossay
- ChEMBL_306447 (CHEMBL621166) Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand
- ChEMBL_306463 (CHEMBL875951) Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand
- ChEMBL_527767 (CHEMBL645755) Agonist activity at human ERalpha expressed in african green monkey CV1 cells by luciferase reporter gene assay relative to 17beta estradiol
- ChEMBL_619853 (CHEMBL634176) Inhibition of human 17beta-HSD7 expressed in HEK293 cells assessed as inhibition of reduction of [14C]estrone into [14C]estradiol after 7 hrs
- ChEMBL_66406 (CHEMBL623348) Inhibitory activity against Estrogen receptor by displacement of [3H]17-beta-estradiol in ER-rich cytosol from rabbit uterine tissue
- ChEMBL_99805 (CHEMBL873827) In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiol
- Radioligand Displacement Assay Binding affinity was measured by a scintillation proximity binding assay using [3H]4-OHT (for ERRgamma) or [3H]estradiol (for ERalpha) as radioligand.
- ChEMBL_1467008 (CHEMBL924912) Inhibition of FASN in human PANC1 cells assessed as inhibition of [14C]acetate incorporation preincubated for 4 hrs before [14C]acetate addition measured after 2 hrs by scintillation counting
- ChEMBL_1467009 (CHEMBL924913) Inhibition of FASN in human BxPC3 cells assessed as inhibition of [14C]acetate incorporation preincubated for 4 hrs before [14C]acetate addition measured after 2 hrs by scintillation counting
- ChEMBL_1778534 Inhibition of human liver carboxylesterase 1 using o-nitrophenyl acetate as substrate
- ChEMBL_78556 (CHEMBL620319) Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.
- ChEMBL_1677382 (CHEMBL1279298) Inhibition of ACC1 in human HCT116 cells assessed as reduction of [14C]acetate uptake preincubated for 60 mins followed by addition of [14C]acetate and measured after 2 hrs by scintillation counting analysis
- ChEMBL_1361782 Antagonist activity at estrogen receptor in human MCF7 cells assessed as inhibition of estradiol-induced cell proliferation after 5 days by WST-8 assay
- ChEMBL_1491711 (CHEMBL949566) Inhibition of human MRP2-mediated estradiol-17beta-D-glucuronide formation using inside-out membrane vesicles by LC-MS/MS analysis
- ChEMBL_1822722 (CHEMBL2040039) Displacement of [3H]-estradiol from human recombinant estrogen receptor expressed in insect cells incubated for 17 hrs by radioactive receptor binding assay
- ChEMBL_775706 (CHEMBL686723) Transactivation activity of glucocorticoid receptor in HFF assessed as induction of aromatase activity by measuring beta-estradiol activity after 18 to 24 hrs by ELISA
- ChEBML_1697025 Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysis
- ChEMBL_1762692 (CHEMBL1817510) Inhibition of human liver carboxylesterase 1 using o-nitrophenyl acetate as substrate
- ChEMBL_2032946 (CHEMBL646336) Inhibition of human erythrocyte CA1 using 4-nitrophenyl acetate as substrate by spectrophotometry
- ChEMBL_2032947 (CHEMBL646337) Inhibition of human erythrocyte CA2 using 4-nitrophenyl acetate as substrate by spectrophotometry
- ChEMBL_463122 (CHEMBL672268) Inhibition of human carbonic anhydrase 1 assessed as 4-nitrophenyl acetate hydrolysis
- ChEMBL_463123 (CHEMBL672269) Inhibition of human carbonic anhydrase 2 assessed as 4-nitrophenyl acetate hydrolysis
- ChEMBL_463124 (CHEMBL672270) Inhibition of mouse carbonic anhydrase 13 assessed as 4-nitrophenyl acetate hydrolysis
- ChEMBL_520160 (CHEMBL634856) Inhibition of human liver CE1-mediated O-nitrophenyl acetate hydrolysis by spectrophotometry
- ChEMBL_697897 (CHEMBL708428) Inhibition of human intestinal CE1 using O-nitrophenyl acetate as substrate by spectrophotometry
- ChEBML_1685129 Antagonist activity at ERalpha (unknown origin) expressed in HEK293T cells assessed as inhibition of estradiol-induced response after 24 hrs by luciferase reporter gene assay
- ChEMBL_1287641 Competitive inhibition of ER-alpha (unknown origin) ligand binding pocket expressed in ER-negative human SKBR3 cells coexpressing ERE using estradiol as substrate
- ChEMBL_1337645 Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase reporter gene assay
- ChEMBL_1337649 Antagonist activity at human Gal4-fused ER-beta expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase reporter gene assay
- ChEMBL_1494637 (CHEMBL943291) Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells assessed as reduction of [3H]estradiol-17beta-glucuronide uptake after 3 mins by beta-counting
- ChEMBL_1494638 (CHEMBL943292) Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cells assessed as reduction of [3H]estradiol-17beta-glucuronide uptake after 3 mins by beta-counting
- ChEMBL_1562015 (CHEMBL1013646) Inhibition of CDK8 (unknown origin) expressed in 7dF3 clone of human HEK293 cells preincubated for 2 hrs followed by addition of beta-estradiol by luciferase assay
- ChEMBL_1664063 (CHEMBL1261302) Downregulation of ERalpha in human MCF-7 cells assessed as reduction of estradiol-induced GREB1 mRNA levels after 24 hrs by RT-PCR method
- ChEMBL_1664064 (CHEMBL1261303) Downregulation of ERalpha in human MCF-7 cells assessed as reduction of estradiol-induced PgR mRNA levels after 24 hrs by RT-PCR method
- ChEMBL_1664065 (CHEMBL1261304) Downregulation of ERalpha in human MCF-7 cells assessed as reduction of estradiol-induced pS2 mRNA levels after 24 hrs by RT-PCR method
- ChEMBL_1744042 (CHEMBL1768147) Inhibition of human 17beta-HSD2 expressed in HEK293 cell lysates incubated for 10 mins using [2,4,6,7-3H]-estradiol and NAD+ by scintillation counting method
- ChEMBL_1767338 (CHEMBL1825450) Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length estrogen receptor alpha after 2 hrs by fluorescence polarization assay
- ChEMBL_1767339 (CHEMBL1825451) Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length estrogen receptor beta after 2 hrs by fluorescence polarization assay
- ChEMBL_1869281 Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of estradiol-driven cell growth measured after 7 days by SYTOX green-based assay
- ChEMBL_822871 (CHEMBL638936) Antagonist activity at Estrogen receptor expressed in human Ishikawa cells assessed as inhibition of estradiol-induced increase in alkaline phosphatase after 3 days by spectrophotometry
- ChEMBL_879539 (CHEMBL691020) Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol after 24 hrs by thin layer chromatography
- ChEMBL_1840943 (CHEMBL2090981) Inhibition of ACC1 in human HCT116 cells assessed as reduction in [14C]acetate uptake preincubated for 60 mins followed by [14C]acetate addition and measured after 2 hrs by top count scintillation counting method
- ChEMBL_1908133 (CHEMBL3066003) Inhibition of ACC1 in human HCT116 cells assessed as reduction in [14C]acetate uptake preincubated for 60 mins followed by [14C]acetate addition and measured after 2 hrs by top count scintillation counting method
- ChEBML_1685205 Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer substrate by scintillation counting method
- ChEMBL_1361049 Antagonist activity at ER in human MCF7:WS8 cells assessed as inhibition of estradiol-induced cell growth by measuring DNA level after 7 days by fluorescence analysis
- ChEMBL_1367283 (CHEMBL867306) Inhibition of human placental 17beta-HSD2 microsomal fraction using [2, 4, 6, 7-3H]-estradiol as substrate after 20 mins by HPLC analysis
- ChEMBL_1684871 (CHEMBL1286195) Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH-P450 reductase using 4-estradiol as substrate in presence of NADP+ by HPLC analysis
- ChEMBL_1767356 (CHEMBL1825468) Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length untagged estrogen receptor alpha expressed in Spodoptera frugiperda by fluorescence polarization assay
- ChEMBL_1767357 (CHEMBL1825469) Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length untagged estrogen receptor beta expressed in insect cells by fluorescence polarization assay
- ChEMBL_1870077 Antagonist activity at estrogen receptor beta (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based luciferase reporter gene assay
- ChEMBL_1870096 Antagonist activity at estrogen receptor alpha (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based luciferase reporter gene assay
- ChEMBL_1934447 (CHEMBL2321166) Displacement of fluorescein-labeled PGC1alpha peptide from human GST-tagged ERalpha LBD after 2 hrs in presence of estradiol-beta by TR-FRET assay
- ChEMBL_474434 (CHEMBL684864) Antagonist activity at human ER ligand binding domain expressed in african green monkey COS7 cells in presence of 17-beta-estradiol by Gal4 hybrid assay
- ChEMBL_527053 (CHEMBL632930) Antiestrogenic activity at estrogen receptor alpha expressed in yeast cells assessed as inhibition of 17-beta-estradiol-induced beta-galactosidase activity by two hybrid assay
- ChEMBL_622102 (CHEMBL641241) Antagonist activity at estrogen receptor in human Ishikawa cells assessed as 17-beta-estradiol-induced alkaline phosphatase activity after 3 days by chemiluminescence assay
- ChEMBL_861318 (CHEMBL670093) Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate after 20 mins by HPLC analysis in presence of NAD+
- ChEMBL_988475 (CHEMBL701099) Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabeled, [2,4,6,7-3H]-estradiol as substrate after 20 mins by HPLC analysis in presence of NAD+
- ChEMBL_1549819 (CHEMBL999861) Inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysis
- ChEMBL_2054747 (CHEMBL667198) Inhibition of human carbonic anhydrase 2 using 4-nitrophenyl acetate as substrate by spectrophotometry
- ChEMBL_564154 (CHEMBL857761) Inhibition of human erythrocyte CA1 esterase activity using 4-nitrophenyl acetate substrate
- ChEMBL_564155 (CHEMBL675970) Inhibition of human erythrocyte CA2 esterase activity using 4-nitrophenyl acetate substrate
- ChEMBL_791004 (CHEMBL701424) Inhibition of pig liver carboxylesterase using p-nitrophenyl acetate as substrate by spectrophotometric analysis
- ChEMBL_1343606 Apparent inhibition of human placental microsomal aromatase assessed as [C14]estrone/[C14]estradiol formation using 0.075 to 0.515 uM [C14]androstenedione substrate by liquid scintillation counting
- ChEMBL_1649840 (CHEMBL1219538) Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by luciferase reporter gene assay
- ChEMBL_1890699 Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins by LC-MS/MS analysis
- ChEMBL_2046646 (CHEMBL658901) Inhibition of estrogen sulfotransferase in human liver cytosol incubated for 30 mins in presence of [3H]-estradiol and adenosine -3'-phosphate 5'-phosphosulfate by liquid scintillation counting method
- ChEMBL_622103 (CHEMBL641242) Antagonist activity at estrogen receptor in human MCF7 cells assessed as 17-beta-estradiol-induced cell proliferation after 24 hrs by [14C]thymidine incorporation assay
- ChEMBL_651562 (CHEMBL660951) Antagonist activity at human wild type ERbeta expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivation by luciferase reporter gene assay
- ChEMBL_651565 (CHEMBL660954) Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivation by luciferase reporter gene assay
- ChEMBL_718372 (CHEMBL634339) Antagonist activity at human ERalpha LBD in human MCF7 cells assessed as inhibition of estradiol-induced cell proliferation after up to 6 days by celltiter-glo assay
- ChEMBL_1551183 (CHEMBL997402) Inhibition of human carbonic anhydrase-1 using p-nitrophenyl acetate as substrate by esterase assay
- ChEMBL_1551184 (CHEMBL997403) Inhibition of human carbonic anhydrase-2 using p-nitrophenyl acetate as substrate by esterase assay
- ChEMBL_591600 (CHEMBL701190) Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry
- ChEMBL_591603 (CHEMBL701193) Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetry
- ChEMBL_591604 (CHEMBL701194) Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry
- ChEMBL_628071 (CHEMBL640642) Inhibition of human HDAC1 assessed as [3H]acetate release after 90 mins by scintillation counting
- ChEMBL_1484075 (CHEMBL1005282) Inhibition of human OATP1B3 expressed in BacMam baculovirus virus infected HEK MSR2 cells using [3H]estradiol 17beta-D-glucuronide as substrate by liquid scintillation counting analysis
- ChEMBL_1684870 (CHEMBL1286194) Inhibition of human CYP1B1 expressed in Escherichia coli DH5alpha coexpressing human NADPH-P450 reductase using 4-estradiol as substrate in presence of NADP+ by Michaelis-Menten plot analysis
- ChEMBL_1890700 Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins by LC-MS/MS analysis
- ChEMBL_1890701 Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins by LC-MS/MS analysis
- ChEMBL_2074716 (CHEMBL686630) Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell based luciferase reporter gene assay
- ChEMBL_2074717 (CHEMBL688916) Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell based luciferase reporter gene assay
- Estrogen Receptor Binding and Transcription Activation Assay Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ER. Hydroxyapatite was used to adsorb the receptor-ligand complexes, and free ligand was washed away. The binding affinities are expressed as relative binding affinity (RBA) values with the RBA of estradiol set to 100%. The values given are the average +/- range or SD of two to three independent determinations. Estradiol binds to ERalpha with a Kd of 0.2 nM and to ERbeta with a Kd of 0.5 nM. EC50/IC50 values were obtained from transcription activation by ER gene transfection in human endometrial cancer cells.
- ChEMBL_1452411 (CHEMBL902647) Inhibition of bovine erythrocyte carbonic anhydrase 2 using 4-nitrophenyl acetate substrate by photometric assay
- ChEMBL_1671094 (CHEMBL1266313) Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysis
- ChEMBL_2032949 (CHEMBL646339) Inhibition of human erythrocyte CA2 using 4-nitrophenyl acetate as substrate by Lineweaver-Burk plot analysis
- ChEMBL_762141 (CHEMBL675897) Inhibition of human liver carboxylesterase1 using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry
- ChEMBL_762142 (CHEMBL675898) Inhibition of human intestinal carboxylesterase using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry
- ChEMBL_762143 (CHEMBL675899) Inhibition of rabbit liver carboxylesterase using o-nitrophenyl acetate as substrate after for 5 mins by spectrophotometry
- Spectroscopic Assay Formation of the hydroxylated product and depletion of NADPH were measured following ethyl acetate extraction of the reaction mixture.
- ChEMBL_101082 (CHEMBL616405) Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-estradiol (in vitro)
- ChEMBL_536775 (CHEMBL650297) Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase based mammalian two-hybrid assay
- ChEMBL_1339080 (CHEMBL867716) Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional activation after 24 hrs by ERE-luciferase reporter gene assay
- ChEMBL_1934446 (CHEMBL2321165) Displacement of europium-labeled SRC1 peptide from full length human recombinant ERalpha expressed in baculovirus expression system after 1.5 hrs in presence of estradiol-beta by TR-FRET assay
- ChEMBL_536774 (CHEMBL650296) Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activity after 24 hrs by luciferase reporter gene assay
- ChEMBL_536780 (CHEMBL650301) Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 100 nM estradiol-induced transcriptional activity after 24 hrs by luciferase reporter gene assay
- ChEMBL_969612 (CHEMBL679552) Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activation after 20 hrs by luciferase reporter gene assay
- ChEMBL_1986667 (CHEMBL2437868) Inhibition of human carbonic anhydrase 2 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysis
- ChEMBL_1986668 (CHEMBL2437869) Inhibition of human carbonic anhydrase 9 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysis
- ChEMBL_1986669 (CHEMBL2437870) Inhibition of human carbonic anhydrase 5A using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysis
- ChEMBL_2032948 (CHEMBL646338) Inhibition of human erythrocyte CA1 b using 4-nitrophenyl acetate as substrate by Lineweaver-Burk plot analysis
- ChEMBL_2107117 (CHEMBL718148) Inhibition of human carbonic anhydrase 2 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysis
- ChEMBL_2107118 (CHEMBL718149) Inhibition of human carbonic anhydrase 9 using p-nitrophenyl acetate as substrate by UV-VIS spectrophotometric analysis
- ChEMBL_771324 (CHEMBL680122) Inhibition of FAS in mouse N42 cells assessed as [14C]-acetate incorporation after 4 hrs by scintillation counting
- Esterase Activity Assay Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.
- ChEMBL_1670787 (CHEMBL1265088) Binding affinity to recombinant human GFP-fused ERalpha LBD (301 to 553 residues) expressed in Escherichia coli BL21(DE3) after 40 mins in presence of 17beta-estradiol by fluorescence polarization assay
- ChEMBL_1670788 (CHEMBL1265089) Binding affinity to recombinant human GFP-fused ERbeta LBD (259 to 498 residues) expressed in Escherichia coli BL21(DE3) after 40 mins in presence of 17beta-estradiol by fluorescence polarization assay
- ChEMBL_1674627 (CHEMBL1273774) Induction of selective estrogen receptor alpha degradation in human MCF7 cells harboring TK-ERE-Luc assessed as reduction in estradiol-induced GREB1 mRNA expression after 24 hrs by TaqMan assay
- ChEMBL_1778275 Antagonist activity at recombinant human ERalpha expressed in HEK293 cells assessed as inhibition of estradiol-induced YFP-fused SRC1 coactivator recruitment measured after 1 hr in presence of Coelenterazine H by BRET assay
- ChEMBL_1993610 Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells incubated for 1 hr by liquid scintillation counting method
- ChEMBL_1993611 Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells incubated for 1 hr by liquid scintillation counting method
- ChEMBL_1278120 Inhibition of human kallikrein using H-Pro-Phe-Arg-AMC acetate salt as substrate measured for 30 mins by spectrophotometry
- ChEMBL_1464326 (CHEMBL952005) Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric method
- ChEMBL_1881816 (CHEMBL2211075) Inhibition of human carbonic anhydrase 2 using 4-nitrophenyl acetate as substrate after 20 mins by spectrophotometric analysis
- ChEMBL_2102188 (CHEMBL711817) Inhibition of human ABHD6 expressed in Expi293 cells using p-nitrophenyl acetate as substrate incubated for 30 mins by spectrophotometry
- ChEMBL_591599 (CHEMBL701189) Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry
- ChEMBL_591602 (CHEMBL701192) Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry
- ChEMBL_615079 (CHEMBL633603) Inhibition of human carbonic anhydrase 2 assessed as conversion of 4-nitrophenyl acetate to 4-nitrophnolate after 5 mins
- ChEMBL_80669 (CHEMBL615745) In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporation
- ChEMBL_1674615 (CHEMBL1273762) Induction of selective estrogen receptor alpha degradation in human MCF7 cells harboring TK-ERE-Luc assessed as reduction in estradiol-induced transcriptional activity after 24 hrs by luciferase reporter gene assay
- ChEMBL_1678645 (CHEMBL1281892) Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay
- ChEMBL_1678647 (CHEMBL1281894) Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay
- ChEMBL_1776993 Antagonist activity at full length recombinant human ERalpha expressed in baculovirus expression system assessed as inhibition of estradiol-induced Euphorium-labelled LTERHKILHRLLQEGSPSD peptide recruitment after 1.5 hrs by time-resolved fluorescence assay
- ChEMBL_1776994 Antagonist activity at full length recombinant human ERbeta expressed in baculovirus expression system assessed as inhibition of estradiol-induced Euphorium-labelled QAQQKSLLQQLLTE peptide recruitment after 1.5 hrs by time-resolved fluorescence assay
- ChEBML_80478 Inhibition of cellular HMG-CoA reductase in cultures of human HEP G2 cells, determined by decreased incorporation of sodium [14C]acetate into cholesterol.
- ChEMBL_1440135 (CHEMBL890446) Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilization
- ChEMBL_1778962 Inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate incubated for 10 mins followed by substrate addition by spectrophotometric method
- ChEMBL_1812048 (CHEMBL2013474) Inhibition of Aurora A (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence method
- ChEMBL_2122327 (CHEMBL730926) Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analysis
- ChEMBL_1678646 (CHEMBL1281893) Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 10 mins by membrane vesicle transport assay
- ChEMBL_1859158 (CHEMBL2169574) Antagonist activity at human full-length ERalpha expressed in non-human mammalian expression system assessed as inhibition of 17beta-estradiol-induced response measured after 22 to 24 hrs by luciferase reporter gene assay
- ChEMBL_1859159 (CHEMBL2169575) Antagonist activity at human full-length ERbeta expressed in non-human mammalian expression system assessed as inhibition of 17beta-estradiol-induced response measured after 22 to 24 hrs by luciferase reporter gene assay
- ChEMBL_616793 (CHEMBL876644) Antagonist activity at human recombinant ERalpha LBD expressed in HEK293 cells assessed as inhibition of 0.3 nM estradiol-induced transcriptional activation after 16 to 18 hrs by GAL4-dependent luciferase reporter gene assay
- ChEMBL_616795 (CHEMBL632782) Antagonist activity at human recombinant ERbeta LBD expressed in HEK293 cells assessed as inhibition of 0.3 nM estradiol-induced transcriptional activation after 16 to 18 hrs by GAL4-dependent luciferase reporter gene assay
- ChEMBL_786678 (CHEMBL694190) Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by radio flow detector-based HPLC analysis in presence of NAD+ as cofactor
- ChEMBL_1484073 (CHEMBL1005280) Inhibition of human MRP2 expressed in baculovirus-infected Sf9 cell membrane vesicle using [3H]estradiol 17beta-D-glucuronide as substrate preincubated with vesicles for 5 mins prior to substrate addition by liquid scintillation counting analysis
- ChEMBL_1668112 (CHEMBL1262162) Antagonist activity at estrogen receptor in mouse GT1-7 cells harboring beta-galactosidase reporter gene assessed as reduction in 17beta-estradiol induced response measured after 20 to 24 hrs by luciferase reporter gene assay
- ChEMBL_1750176 (CHEMBL1787869) Antagonist activity at CMV-fused ERalpha-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of estradiol-induced receptor transactivation after 16 hrs by bright-Glo luciferase reporter gene assay
- ChEMBL_1750177 (CHEMBL1787870) Antagonist activity at CMV-fused ERbeta-LBD-GAL4-DBD (unknown origin) expressed in HEK293T cells assessed as inhibition of estradiol-induced receptor transactivation after 16 hrs by bright-Glo luciferase reporter gene assay
- Estrogen Receptor Binding Assay and Cell-Based Transcriptional Assay The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determined by saturation binding to ER receptors. The IC50 values for compounds were converted to Ki using Cheng-Prusoff equation. The functional activity and selectivity was measured using a transcription assay in the cotransfected human prostate cancer PC3/ER (alpha or beta)-ERE cell line, and EC50 values were determined by computer fit to a concentration-response curve.
- ChEMBL_1524266 (CHEMBL978494) Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins by spectrophotometer analysis
- ChEMBL_1704270 (CHEMBL1660918) Inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate preincubated for 10 mins followed by substrate addition by spectrophotometric analysis
- ChEMBL_1812049 (CHEMBL2013475) Inhibition of Aurora B (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence method
- ChEMBL_2122326 (CHEMBL730925) Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting analysis
- ChEMBL_487696 (CHEMBL697482) Inhibition of human recombinant carbonic anhydrase 2 assessed as activity of carbonic anhydrase 2 esterase activity against 4-nitrophenyl acetate
- ChEMBL_1497344 (CHEMBL999383) Antagonist activity at human estrogen receptor alpha expressed in CHOK1 cells assessed as inhibition of beta-estradiol-induced protein interaction with steroid receptor co-activator peptide after overnight incubation by beta-galactosidase reporter gene assay