Query String: HISTAMINE
Histamine BDBM22861
Histamine CHEMBL544208 BDBM7966 CHEMBL90 2-(1H-imidazol-4-yl)ethan-1-amine Peremin Ceplene HISTAMINE DIHYDROCHLORIDE Ergotidine [3H]histamine L-histamine
BDBM22554 [3H]histamine
HISTAMINE DIHYDROCHLORIDE BDBM50394702
BDBM50121205 Histamine CHEBI:18295
BDBM86172 2-(3-Chlorophenyl)histamine
BDBM86173 2-(3-Iodophenyl)histamine
BDBM50463187 D-Histamine D-Histidine CHEBI:27947 D-His
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- de Graaf, C; Kooistra, AJ; Vischer, HF; Katritch, V; Kuijer, M; Shiroishi, M; Iwata, S; Shimamura, T; Stevens, RC; de Esch, IJ; Leurs, R Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor. J Med Chem 54: 8195-206 (2011)
- Kawanishi, Y; Ishihara, S; Tsushima, T; Seno, K; Miyagoshi, M; Hagishita, S; Ishikawa, M; Shima, N; Shimamura, M; Ishihara, Y Design, synthesis, and pharmacological evaluation of dual histamine H2 and gastrin receptor antagonists Bioorg Med Chem Lett 6: 1421-1426 (1996)
- Linney, ID; Buck, IM; Harper, EA; Kalindjian, SB; Pether, MJ; Shankley, NP; Watt, GF; Wright, PT Design, synthesis, and structure-activity relationships of novel non-imidazole histamine H(3) receptor antagonists. J Med Chem 43: 2362-70 (2000)
- Sasho, S; Seishi, T; Kawamura, M; Hirose, R; Toki, S; Shimada, JI Diamine derivatives containing imidazolidinylidene propanedinitrile as a new class of histamine H3 receptor antagonists. Part I. Bioorg Med Chem Lett 18: 2288-91 (2008)
- Lim, HD; Smits, RA; Bakker, RA; van Dam, CM; de Esch, IJ; Leurs, R Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem 49: 6650-1 (2006)
- Kiss, R; Kiss, B; Könczöl, A; Szalai, F; Jelinek, I; László, V; Noszál, B; Falus, A; Keseru, GM Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening. J Med Chem 51: 3145-53 (2008)
- Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 28: 519-26 (2003)
- Yates, SL; Phillips, JG; Gregory, R; Pawlowski, GP; Fadnis, L; Khan, MA; Ali, SM; Tedford, CE Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands. J Pharmacol Exp Ther 289: 1151-9 (1999)
- Nersesian, DL; Black, LA; Miller, TR; Vortherms, TA; Esbenshade, TA; Hancock, AA; Cowart, MD In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorg Med Chem Lett 18: 355-9 (2008)
- Watanabe, M; Hirokawa, T; Kobayashi, T; Yoshida, A; Ito, Y; Yamada, S; Orimoto, N; Yamasaki, Y; Arisawa, M; Shuto, S Investigation of the bioactive conformation of histamine H3 receptor antagonists by the cyclopropylic strain-based conformational restriction strategy. J Med Chem 53: 3585-93 (2010)
- Ishikawa, M; Watanabe, T; Kudo, T; Yokoyama, F; Yamauchi, M; Kato, K; Kakui, N; Sato, Y Investigation of the histamine H3 receptor binding site. Design and synthesis of hybrid agonists with a lipophilic side chain. J Med Chem 53: 6445-56 (2010)
- Smits, RA; Lim, HD; van der Meer, T; Kuhne, S; Bessembinder, K; Zuiderveld, OP; Wijtmans, M; de Esch, IJ; Leurs, R Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics. Bioorg Med Chem Lett 22: 461-7 (2011)
- Kitbunnadaj, R; Hashimoto, T; Poli, E; Zuiderveld, OP; Menozzi, A; Hidaka, R; de Esch, IJ; Bakker, RA; Menge, WM; Yamatodani, A; Coruzzi, G; Timmerman, H; Leurs, R N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist. J Med Chem 48: 2100-7 (2005)
- Ali, SM; Tedford, CE; Gregory, R; Yates, SL; Phillips, JG New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine. Bioorg Med Chem Lett 8: 1133-8 (1999)
- Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series. Bioorg Med Chem Lett 21: 5384-8 (2011)
- Mikó, T; Ligneau, X; Pertz, HH; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem 46: 1523-30 (2003)
- Letavic, MA; Aluisio, L; Atack, JR; Bonaventure, P; Carruthers, NI; Dugovic, C; Everson, A; Feinstein, MA; Fraser, IC; Hoey, K; Jiang, X; Keith, JM; Koudriakova, T; Leung, P; Lord, B; Lovenberg, TW; Ly, KS; Morton, KL; Motley, ST; Nepomuceno, D; Rizzolio, M; Rynberg, R; Sepassi, K; Shelton, J Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development. Bioorg Med Chem Lett 20: 4210-4 (2010)
- Selivanova, SV; Honer, M; Combe, F; Isensee, K; Stark, H; Krämer, SD; Schubiger, PA; Ametamey, SM Radiofluorinated histamine H3 receptor antagonist as a potential probe for in vivo PET imaging: radiosynthesis and pharmacological evaluation. Bioorg Med Chem 20: 2889-96 (2012)
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- Lipani, L; Odadzic, D; Weizel, L; Schwed, JS; Sadek, B; Stark, H Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs. Eur J Med Chem 86: 578-88 (2014)
- Sun, M; Zhao, C; Gfesser, GA; Thiffault, C; Miller, TR; Marsh, K; Wetter, J; Curtis, M; Faghih, R; Esbenshade, TA; Hancock, AA; Cowart, M Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency. J Med Chem 48: 6482-90 (2005)
- Becknell, NC; Lyons, JA; Aimone, LD; Huang, Z; Gruner, JA; Raddatz, R; Hudkins, RL Synthesis and evaluation of 4- and 5-pyridazin-3-one phenoxypropylamine analogues as histamine-3 receptor antagonists. Bioorg Med Chem 20: 3880-6 (2012)
- Gao, LJ; Schwed, JS; Weizel, L; De Jonghe, S; Stark, H; Herdewijn, P Synthesis and evaluation of novel ligands for the histamine H4 receptor based on a pyrrolo[2,3-d]pyrimidine scaffold. Bioorg Med Chem Lett 23: 132-7 (2012)
- Nagase, T; Mizutani, T; Sekino, E; Ishikawa, S; Ito, S; Mitobe, Y; Miyamoto, Y; Yoshimoto, R; Tanaka, T; Ishihara, A; Takenaga, N; Tokita, S; Sato, N Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists. J Med Chem 51: 6889-901 (2008)
- Nagase, T; Mizutani, T; Ishikawa, S; Sekino, E; Sasaki, T; Fujimura, T; Ito, S; Mitobe, Y; Miyamoto, Y; Yoshimoto, R; Tanaka, T; Ishihara, A; Takenaga, N; Tokita, S; Fukami, T; Sato, N Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists. J Med Chem 51: 4780-9 (2008)
- Latacz, G; Kechagioglou, P; Papi, R; Lazewska, D; Wiecek, M; Kaminska, K; Wencel, P; Karcz, T; Schwed, JS; Stark, H; Kyriakidis, DA; Kiec-Kononowicz, K The Synthesis of 1,3,5-triazine Derivatives and JNJ7777120 Analogues with Histamine H4 Receptor Affinity and Their Interaction with PTEN Promoter. Chem Biol Drug Des 88: 254-63 (2016)
- Birnkammer, T; Spickenreither, A; Brunskole, I; Lopuch, M; Kagermeier, N; Bernhardt, G; Dove, S; Seifert, R; Elz, S; Buschauer, A The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H2 receptor agonists. J Med Chem 55: 1147-60 (2012)
- ChEMBL_1897651 (CHEMBL4399686) Displacement of [3H] histamine from human H4 histamine receptor
- ChEMBL_305947 (CHEMBL832787) Inhibition of [3H]histamine binding to human H4 histamine receptor
- ChEMBL_407552 (CHEMBL855020) Displacement of [3H]histamine from human histamine H4 receptor
- ChEMBL_604300 (CHEMBL1066756) Displacement of [3H]Histamine from human histamine H4 receptor
- ChEMBL_612767 (CHEMBL1071593) Displacement of [3H]histamine from human histamine H4 receptor
- ChEMBL_625986 (CHEMBL1103505) Displacement of [3H]histamine human recombinant histamine H4 receptor
- ChEMBL_744294 (CHEMBL1772151) Displacement of [3H]histamine from human histamine H4 receptor
- ChEMBL_1434446 (CHEMBL3388263) Displacement of [3H]histamine from human recombinant histamine H4 receptor
- ChEMBL_1461283 (CHEMBL3396057) Displacement of [3H]histamine from human recombinant histamine H4 receptor
- ChEMBL_1521724 (CHEMBL3626547) Displacement of [3H]histamine from human recombinant histamine H4 receptor
- ChEMBL_1521725 (CHEMBL3626548) Displacement of [3H]histamine from mouse recombinant histamine H4 receptor
- ChEMBL_1521729 (CHEMBL3626552) Displacement of [3H]histamine from rat recombinant histamine H4 receptor
- ChEMBL_634016 (CHEMBL1117989) Displacement of [3H]histamine from human recombinant histamine H4 receptor
- ChEMBL_634021 (CHEMBL1117994) Displacement of [3H]histamine from mouse recombinant histamine H4 receptor
- ChEMBL_786095 (CHEMBL1919838) Displacement of [3H]histamine from recombinant human histamine H4 receptor
- ChEMBL_87092 (CHEMBL700770) Displacement of [3H]- histamine from the recombinant human histamine H4 receptor
- ChEMBL_87237 (CHEMBL696457) Inhibition against histamine-metabolizing enzyme Histamine N-methyl-transferase
- ChEMBL_1521728 (CHEMBL3626551) Displacement of [3H]histamine from guinea pig recombinant histamine H4 receptor
- ChEMBL_619277 (CHEMBL1100657) Displacement of [3H]histamine from histamine H3 receptor in rat cerebral cortex
- Histamine H-4 Receptor Binding Assay Histamine H-4 Receptor Binding Assay
- ChEMBL_1521718 (CHEMBL3626541) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells
- ChEMBL_1521722 (CHEMBL3626545) Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293T cells
- ChEMBL_1521723 (CHEMBL3626546) Displacement of [3H]histamine from mouse histamine H4 receptor expressed in HEK293T cells
- ChEMBL_475717 (CHEMBL934603) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells
- ChEMBL_512527 (CHEMBL967017) Displacement of [3H]alpha methyl histamine from human cloned histamine H3 receptor
- ChEMBL_556996 (CHEMBL958182) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells
- ChEMBL_613511 (CHEMBL1072277) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cells
- ChEMBL_619282 (CHEMBL1100662) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells
- ChEMBL_621971 (CHEMBL1104113) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells
- ChEMBL_828300 (CHEMBL2050319) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells
- ChEMBL_83635 (CHEMBL695765) Inhibition of human Histamine H3 receptor using [3H]N-alpha-methyl histamine
- ChEMBL_86759 (CHEMBL693568) Inhibition of rat Histamine H3 receptor using [3H]N-alpha-methyl histamine
- ChEMBL_938256 (CHEMBL2328679) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells
- ChEMBL_955844 (CHEMBL2379701) Displacement of [3H]histamine from human histamine H2 receptor expressed in HEK cells
- ChEMBL_955845 (CHEMBL2379702) Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells
- ChEBML_83646 Binding affinity towards human Histamine H3 receptor using [3H]N-methyl-histamine as radioligand
- ChEMBL_1521721 (CHEMBL3626544) Displacement of [3H]histamine from guinea pig histamine H4 receptor expressed in HEK293T cells
- ChEMBL_1621033 (CHEMBL3863316) Antagonist activity at human histamine H4 receptor assessed as inhibition of histamine-induced calcium flux
- ChEMBL_801168 (CHEMBL1949039) Inverse agonist activity at human histamine H3 histamine receptor by [35S]GTPgammaS binding assay
- ChEMBL_86758 (CHEMBL693567) Affinity against rat Histamine H3 receptor using [3H]N-alpha-methyl histamine
- ChEMBL_86763 (CHEMBL698663) Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine
- ChEMBL_325600 (CHEMBL860282) Displacement of [3H]histamine from recombinant human histamine H4 receptor in SK-N-MC cells
- ChEMBL_366416 (CHEMBL853360) Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells
- ChEMBL_552365 (CHEMBL1005955) Displacement of [3H]histamine from human histamine H4 receptor expressed in SK-NM-C cells
- ChEMBL_572927 (CHEMBL1036179) Displacement of [3H]N-alpha methyl histamine from rat cortical membrane histamine H3 receptor
- ChEMBL_87238 (CHEMBL696458) Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamine
- ChEBML_84420 Antagonism of the human histamine H1 receptor
- ChEBML_84863 Affinity towards histamine H1 receptor
- ChEBML_85064 Histamine H2 receptor antagonistic activity
- ChEBML_85686 Affinity towards histamine H2 receptor
- ChEMBL_447501 (CHEMBL896524) Inhibition of histamine H3 receptor
- ChEMBL_447508 (CHEMBL896531) Inhibition of histamine H1 receptor
- ChEMBL_471591 (CHEMBL940222) Inhibition of histamine H3 receptor
- ChEMBL_514044 (CHEMBL979067) Inhibition of histamine H1 receptor
- ChEMBL_535495 (CHEMBL986122) Inhibition of histamine H1 receptor
- ChEMBL_535496 (CHEMBL986123) Inhibition of histamine H2 receptor
- ChEMBL_535497 (CHEMBL986124) Inhibition of histamine H4 receptor
- ChEMBL_538857 (CHEMBL1033100) Inhibition of histamine H1 receptor
- ChEMBL_565949 (CHEMBL960845) Inhibition of histamine H2 receptor
- ChEMBL_577506 (CHEMBL1057858) Inhibition of histamine H1 receptor
- ChEMBL_577507 (CHEMBL1057859) Inhibition of histamine H2 receptor
- ChEMBL_577508 (CHEMBL1057860) Inhibition of histamine H4 receptor
- ChEMBL_577959 (CHEMBL1059632) Inhibition of histamine H1 receptor
- ChEMBL_598547 (CHEMBL1043539) Inhibition of histamine H1 receptor
- ChEMBL_598548 (CHEMBL1043540) Inhibition of histamine H2 receptor
- ChEMBL_598549 (CHEMBL1043541) Inhibition of histamine H3 receptor
- ChEMBL_598550 (CHEMBL1043542) Inhibition of histamine H4 receptor
- ChEMBL_601711 (CHEMBL1050446) Inhibition of histamine H1 receptor
- ChEMBL_601712 (CHEMBL1050447) Inhibition of histamine H2 receptor
- ChEMBL_601713 (CHEMBL1050448) Inhibition of histamine H4 receptor
- ChEMBL_613766 (CHEMBL1068913) Inhibition of histamine H1 receptor
- ChEMBL_614259 (CHEMBL1106922) Activity at histamine H1 receptor
- ChEMBL_615848 (CHEMBL1101958) Inhibition of histamine H2 receptor
- ChEMBL_629975 (CHEMBL1112052) Inhibition of histamine H1 receptor
- ChEMBL_629976 (CHEMBL1112053) Inhibition of histamine H2 receptor
- ChEMBL_760134 (CHEMBL1815390) Inhibition of histamine H1 receptor
- ChEMBL_84419 (CHEMBL691451) Inhibition of histamine H1 receptor
- ChEMBL_85522 (CHEMBL697133) Inhibition of histamine H2 receptor
- ChEMBL_87072 (CHEMBL700589) Inhibition of Histamine H3 receptor
- ChEBML_223735 Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes
- ChEMBL_1364323 (CHEMBL3293717) Displacement of [3H]-histamine from human histamine H4 receptor after 45 mins by scintillation counting analysis
- ChEMBL_218827 (CHEMBL823938) In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileum
- ChEMBL_304042 (CHEMBL840220) Displacement of [3H]histamine binding to SK-N-MC cell membranes expressing human histamine H4 receptor
- ChEMBL_463107 (CHEMBL930013) Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomes
- ChEMBL_615000 (CHEMBL1116877) Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation counting
- ChEMBL_619280 (CHEMBL1100660) Displacement of [3H]histamine from human histamine H4 receptor expressed in SF9 cells coexpressing Galphai2, Gbeta1gamma2
- ChEMBL_87230 (CHEMBL696450) Inhibition of [3H]-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor
- ChEMBL_986996 (CHEMBL2439316) Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates
- ChEMBL_1549481 (CHEMBL3755807) Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting
- ChEMBL_1842058 (CHEMBL4342357) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cell membranes by radioligand displacement assay
- ChEMBL_223735 (CHEMBL843739) Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes
- ChEMBL_366425 (CHEMBL871378) Displacement of [3H]Histamine from human histamine H4 receptor transfected in SK-N-MC cells at 100 nM
- ChEMBL_366426 (CHEMBL871379) Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 300 nM
- ChEMBL_366427 (CHEMBL871380) Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 1 uM
- ChEMBL_366428 (CHEMBL871381) Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 10 nM
- ChEMBL_366429 (CHEMBL871382) Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 30 nM
- ChEMBL_493057 (CHEMBL953171) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced positive chronotropic activity
- ChEMBL_572926 (CHEMBL1036178) Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cells
- ChEMBL_603902 (CHEMBL1048581) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2
- ChEMBL_625969 (CHEMBL1103488) Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay
- ChEMBL_697507 (CHEMBL1638839) Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2
- ChEMBL_83768 (CHEMBL693826) Compound was tested in vitro for histamine H1-antagonist activity against histamine-induced contractions on isolated guinea pig ileum
- ChEMBL_86762 (CHEMBL698662) Compounds were tested for their effect at histamine H3 receptors in vitro on synaptosomes of rat cerebral cortex for the release of [3H]histamine
- ChEMBL_86915 (CHEMBL699053) pBinding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes
- ChEMBL_603320 (CHEMBL1038010) Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 treated 10 to 15 seconds before histamine challenge
- ChEMBL_603321 (CHEMBL1038011) Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2 treated 20 to 30 seconds after histamine challenge
- ChEBML_1688611 Inhibition of histamine H1 receptor (unknown origin)
- ChEBML_83649 Binding affinity for human histamine H3 receptor
- ChEBML_84418 Antagonistic activity against histamine H1 receptor
- ChEBML_84425 Binding affinity to the human Histamine H1 receptor
- ChEBML_84544 Binding affinity against Histamine H1 receptor
- ChEBML_84556 Binding affinity for the human Histamine H1 Receptor
- ChEBML_84864 Binding affinity to cloned Histamine H1 receptor
- ChEBML_85661 Binding affinity for the human Histamine H2 receptor
- ChEBML_87073 In vitro binding affinity for Histamine H3 receptor
- ChEMBL_1574690 (CHEMBL3801557) Inhibition of human histamine H2 receptor
- ChEMBL_1837065 (CHEMBL4337198) Inhibition of human histamine H3 receptor
- ChEMBL_325613 (CHEMBL860224) Binding affinity to histamine H3 receptor
- ChEMBL_329934 (CHEMBL868795) Binding affinity to histamine H1 receptor
- ChEMBL_329935 (CHEMBL868796) Binding affinity to histamine H2 receptor
- ChEMBL_329936 (CHEMBL868797) Binding affinity to histamine H3 receptor
- ChEMBL_329937 (CHEMBL868798) Binding affinity to histamine H4 receptor
- ChEMBL_369374 (CHEMBL869741) Binding affinity to histamine H1 receptor
- ChEMBL_439701 (CHEMBL888812) Binding affinity to histamine H1 receptor
- ChEMBL_439703 (CHEMBL888814) Binding affinity to histamine H3 receptor
- ChEMBL_439704 (CHEMBL888815) Binding affinity to histamine H4 receptor
- ChEMBL_449280 (CHEMBL899542) Binding affinity at human histamine H3
- ChEMBL_452338 (CHEMBL902575) Binding affinity to histamine H1 receptor
- ChEMBL_463175 (CHEMBL948189) Inhibition of human histamine H3 receptor
- ChEMBL_463664 (CHEMBL930832) Binding affinity to histamine H1 receptor
- ChEMBL_464412 (CHEMBL931079) Binding affinity to histamine H1 receptor
- ChEMBL_489018 (CHEMBL986359) Inhibition of human histamine H1 receptor
- ChEMBL_489019 (CHEMBL986360) Inhibition of human histamine H2 receptor
- ChEMBL_489020 (CHEMBL986361) Inhibition of human histamine H4 receptor
- ChEMBL_514298 (CHEMBL979128) Agonist activity at histamine H1 receptor
- ChEMBL_523447 (CHEMBL1008299) Binding affinity to histamine H3 receptor
- ChEMBL_537282 (CHEMBL985378) Inhibition of human histamine H1 receptor
- ChEMBL_537283 (CHEMBL985379) Inhibition of human histamine H2 receptor
- ChEMBL_537284 (CHEMBL985380) Inhibition of human histamine H4 receptor
- ChEMBL_556736 (CHEMBL959799) Binding affinity to histamine H1 receptor
- ChEMBL_556742 (CHEMBL959805) Binding affinity to histamine H2 receptor
- ChEMBL_556759 (CHEMBL960610) Binding affinity to histamine H3 receptor
- ChEMBL_556998 (CHEMBL960689) Binding affinity to histamine H1 receptor
- ChEMBL_558280 (CHEMBL956580) Inhibition of human histamine H1 receptor
- ChEMBL_558281 (CHEMBL957345) Inhibition of human histamine H2 receptor
- ChEMBL_558282 (CHEMBL957346) Inhibition of human histamine H4 receptor
- ChEMBL_562478 (CHEMBL1010981) Inhibition of human histamine H2 receptor
- ChEMBL_579543 (CHEMBL1062331) Inhibition of human histamine H1 receptor
- ChEMBL_579544 (CHEMBL1062332) Inhibition of human histamine H2 receptor
- ChEMBL_579545 (CHEMBL1062333) Inhibition of human histamine H4 receptor
- ChEMBL_612765 (CHEMBL1071591) Binding affinity to histamine H3 receptor
- ChEMBL_625162 (CHEMBL1115183) Binding affinity at histamine H1 receptor
- ChEMBL_625973 (CHEMBL1103492) Binding affinity to histamine H1 receptor
- ChEMBL_625974 (CHEMBL1103493) Binding affinity to histamine H2 receptor
- ChEMBL_625975 (CHEMBL1103494) Binding affinity to histamine H3 receptor
- ChEMBL_697205 (CHEMBL1640625) Binding affinity to Histamine receptor H1
- ChEMBL_697206 (CHEMBL1640626) Binding affinity to Histamine receptor H2
- ChEMBL_697207 (CHEMBL1640627) Binding affinity to Histamine receptor H3
- ChEMBL_697208 (CHEMBL1640628) Binding affinity to Histamine receptor H4
- ChEMBL_714790 (CHEMBL1663596) Inhibition of rat histamine H3 receptor
- ChEMBL_718096 (CHEMBL1671549) Binding affinity to histamine H1 receptor
- ChEMBL_718161 (CHEMBL1679207) Binding affinity to histamine H1 receptor
- ChEMBL_718162 (CHEMBL1679208) Binding affinity to histamine H2 receptor
- ChEMBL_718163 (CHEMBL1679209) Binding affinity to histamine H3 receptor
- ChEMBL_718164 (CHEMBL1679210) Binding affinity to histamine H4 receptor
- ChEMBL_735239 (CHEMBL1694501) Agonistic activity at histamine H4 receptor
- ChEMBL_741662 (CHEMBL1769654) Binding affinity to histamine H1 receptor
- ChEMBL_748973 (CHEMBL1781421) Antagonist activity at histamine H1 receptor
- ChEMBL_788361 (CHEMBL1918042) Antagonist activity at histamine H3 receptor
- ChEMBL_788362 (CHEMBL1918043) Antagonist activity at histamine H1 receptor
- ChEMBL_788363 (CHEMBL1918044) Antagonist activity at histamine H2 receptor
- ChEMBL_796225 (CHEMBL1938190) Antagonist activity at histamine H1 receptor
- ChEMBL_84420 (CHEMBL691452) Antagonism of the human histamine H1 receptor
- ChEMBL_856370 (CHEMBL2160725) Binding affinity to histamine H1 receptor
- ChEMBL_858207 (CHEMBL2167670) Antagonist activity at histamine H1 receptor
- ChEMBL_87085 (CHEMBL700763) Inhibition of human Histamine H4 receptor
- ChEMBL_875630 (CHEMBL2184861) Binding affinity to histamine H1 receptor
- ChEMBL_875720 (CHEMBL2185772) Binding affinity to histamine H1 receptor
- ChEMBL_884070 (CHEMBL2215119) Binding affinity to Histamine H2 receptor
- ChEMBL_884323 (CHEMBL2210356) Binding affinity to Histamine H1 receptor
- ChEMBL_884324 (CHEMBL2210357) Binding affinity to Histamine H3 receptor
- ChEMBL_887243 (CHEMBL2215799) Antagonist activity at histamine H1 receptor
- ChEBML_84894 In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal homogenate
- ChEMBL_1333836 (CHEMBL3231654) Antagonist activity at histamine H2 receptor in Charles River rat assessed as inhibition of histamine-mediated electrically stimulated uterine contraction
- ChEMBL_1577463 (CHEMBL3806736) Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 cells co-expressing mammalian Galphai2 and Gbeta1gamma2
- ChEMBL_2148514 (CHEMBL5032912) Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in sf9 cells by liquid scintillation counting analysis
- ChEMBL_452856 (CHEMBL903099) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced longitudinal smooth muscle contraction
- ChEMBL_535792 (CHEMBL991557) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 5 ug/ml
- ChEMBL_535794 (CHEMBL991559) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.1 mg/ml
- ChEMBL_535795 (CHEMBL991560) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.5 mg/ml
- ChEMBL_535796 (CHEMBL991561) Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 1.0 mg/ml
- ChEMBL_631946 (CHEMBL1104702) Displacement of [3H]N-alpha-methyl-histamine from human histamine H3 receptor expressed in human HEK293-EBNA cells
- ChEMBL_747322 (CHEMBL1776625) Displacement of [3H]histamine from human full-length histamine H4 receptor expressed in HEK293 cells after 60 mins
- ChEMBL_86756 (CHEMBL693566) Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes
- ChEMBL_86898 (CHEMBL698408) Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.
- ChEMBL_86908 (CHEMBL698418) In vitro inhibitory activity against histamine H3 receptor using [3H]histamine as radioligand from rat cerebral cortex synaptosomes
- ChEMBL_87053 (CHEMBL697326) Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes
- ChEMBL_935304 (CHEMBL2318421) Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma
- ChEMBL_977018 (CHEMBL2416542) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Gai2 and Gb1c2 subunit
- ChEMBL_1628377 (CHEMBL3870962) Antagonist activity at human Histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced calcium flux preincubated for 30 mins followed by histamine addition by Fluo-4-AM dye based FLIPR assay
- ChEBML_83647 Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells
- ChEMBL_1280381 (CHEMBL3095541) Antagonist activity at human recombinant histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced effect by FLIPR assay
- ChEMBL_576569 (CHEMBL1034550) Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cells by liquid scintillation counting
- ChEMBL_614999 (CHEMBL1116876) Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting
- ChEMBL_735234 (CHEMBL1694496) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting
- ChEMBL_788365 (CHEMBL1918046) Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting technique
- ChEMBL_790129 (CHEMBL1926408) Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting
- ChEMBL_86901 (CHEMBL698411) In vitro antagonist potency at Histamine H3 receptor measured as K+-evoked [3H]histamine release from synaptosomes of rat cerebral cortex.
- ChEMBL_875614 (CHEMBL2184845) Antagonist activity at histamine H1 receptor expressed in human PC3 cells inhibition of histamine-induced calcium influx by cell based assay
- ChEMBL_957492 (CHEMBL2378230) Displacement of [3H]histamine displacement from human histamine H4 receptor expressed in SK-NM-C cells after 60 mins
- ChEMBL_750445 (CHEMBL1785997) Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium flow during phase-II compound dosed after histamine addition by Fura-2 based fluorometric assay
- ChEBML_1693544 Antagonist activity at histamine H3 receptor (unknown origin)
- ChEBML_84409 Binding constant against histamine H1 receptor (in vivo)
- ChEBML_84539 Selectivity screen against human Histamine H1 receptor
- ChEBML_87054 Binding affinity for the rat cortical Histamine H3 receptor
- ChEMBL_1277728 (CHEMBL3097144) Binding affinity to human histamine H1 receptor
- ChEMBL_1277729 (CHEMBL3097145) Binding affinity to human histamine H2 receptor
- ChEMBL_1339952 (CHEMBL3243859) Inhibition of histamine H1 receptor (unknown origin)
- ChEMBL_1349364 (CHEMBL3269587) Binding affinity to human histamine H3 receptor
- ChEMBL_1349365 (CHEMBL3269588) Binding affinity to rat histamine H3 receptor
- ChEMBL_1437793 (CHEMBL3383590) Binding affinity to human histamine H1 receptor
- ChEMBL_1471679 (CHEMBL3421047) Binding affinity to human histamine H3 receptor
- ChEMBL_1471680 (CHEMBL3421048) Binding affinity to rat histamine H3 receptor
- ChEMBL_1474741 (CHEMBL3424159) Inhibition of histamine H1 receptor (unknown origin)
- ChEMBL_1513234 (CHEMBL3610942) Inhibition of recombinant human histamine H1 receptor
- ChEMBL_1521714 (CHEMBL3626537) Binding affinity to human histamine H4 receptor
- ChEMBL_1521716 (CHEMBL3626539) Binding affinity to mouse histamine H4 receptor
- ChEMBL_1521717 (CHEMBL3626540) Binding affinity to rat histamine H4 receptor
- ChEMBL_1566604 (CHEMBL3791498) Inhibition of histamine H3 receptor (unknown origin)
- ChEMBL_1621015 (CHEMBL3863298) Antagonist activity at human histamine H3 receptor
- ChEMBL_1767248 (CHEMBL4219360) Binding affinity to human histamine H3 receptor
- ChEMBL_1767249 (CHEMBL4219361) Binding affinity to rat histamine H3 receptor
- ChEMBL_1842056 (CHEMBL4342355) Inhibition of histamine H3 receptor (unknown origin)
- ChEMBL_1868872 (CHEMBL4369938) Inhibition of histamine H2 receptor (unknown origin)
- ChEMBL_1868876 (CHEMBL4369942) Inhibition of histamine H3 receptor (unknown origin)
- ChEMBL_1868880 (CHEMBL4369946) Inhibition of histamine H1 receptor (unknown origin)
- ChEMBL_2033537 (CHEMBL4687695) Inhibition of histamine H3 receptor (unknown origin)
- ChEMBL_2118797 (CHEMBL4827863) Inhibition of histamine H1 receptor (unknown origin)
- ChEMBL_2134933 (CHEMBL4844543) Binding affinity to human histamine H1 receptor
- ChEMBL_2172136 (CHEMBL5057270) Antagonist activity at human histamine H3 receptor
- ChEMBL_2265227 Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_305389 (CHEMBL833040) Inhibitory concentration against histamine-H1 receptor
- ChEMBL_320729 (CHEMBL881715) Dissociation constant against histamine H1 receptor
- ChEMBL_320749 (CHEMBL881222) Inhibition constant against histamine H1 receptor
- ChEMBL_320750 (CHEMBL881223) Inhibition constant against histamine H3 receptor
- ChEMBL_320772 (CHEMBL884727) Affinity towards cloned Histamine H1 receptor
- ChEMBL_321262 (CHEMBL881887) Inhibitory concentration against Histamine H1 receptor
- ChEMBL_321263 (CHEMBL881888) Inhibitory concentration against Histamine H2 receptor
- ChEMBL_321265 (CHEMBL881890) Inhibitory concentration against histamine H1 receptor
- ChEMBL_321266 (CHEMBL881891) Inhibitory concentration against histamine H2 receptor
- ChEMBL_438820 (CHEMBL887978) Binding affinity to rat histamine H3 receptor
- ChEMBL_438821 (CHEMBL889157) Binding affinity to human histamine H3 receptor
- ChEMBL_439702 (CHEMBL888813) Binding affinity to from histamine H2 receptor
- ChEMBL_440971 (CHEMBL890061) Binding affinity to human histamine H3 receptor
- ChEMBL_448653 (CHEMBL897804) Binding affinity to human histamine H3 receptor
- ChEMBL_452349 (CHEMBL902586) Binding affinity to human histamine H1 receptor
- ChEMBL_453434 (CHEMBL885433) Binding affinity at human histamine H3 receptor
- ChEMBL_455315 (CHEMBL886091) Binding affinity at human histamine H3 receptor
- ChEMBL_456606 (CHEMBL923983) Binding affinity to human histamine H3 receptor
- ChEMBL_458732 (CHEMBL943016) Binding affinity to human histamine H1 receptor
- ChEMBL_496463 (CHEMBL1004594) Binding affinity to mouse histamine H3 receptor
- ChEMBL_515524 (CHEMBL1036545) Binding affinity to rat histamine H3 receptor
- ChEMBL_515526 (CHEMBL1036547) Binding affinity to human histamine H3 receptor
- ChEMBL_523728 (CHEMBL1007535) Binding affinity to rat histamine H3 receptor
- ChEMBL_557000 (CHEMBL960691) Binding affinity to rat histamine H4 receptor
- ChEMBL_583252 (CHEMBL1055807) Binding affinity to human histamine H3 receptor
- ChEMBL_611516 (CHEMBL1065733) Binding affinity to rat histamine H3 receptor
- ChEMBL_613516 (CHEMBL1074193) Binding affinity to rat histamine H4 receptor
- ChEMBL_621600 (CHEMBL1113032) Binding affinity to human histamine H1 receptor
- ChEMBL_629414 (CHEMBL1105767) Binding affinity to human histamine H3 receptor
- ChEMBL_629438 (CHEMBL1105791) Binding affinity to rat histamine H3 receptor
- ChEMBL_651627 (CHEMBL1228010) Antagonist activity at human histamine H3 receptor
- ChEMBL_651628 (CHEMBL1228011) Antagonist activity at rat histamine H3 receptor
- ChEMBL_651629 (CHEMBL1228012) Antagonist activity at human histamine H1 receptor
- ChEMBL_651630 (CHEMBL1228013) Antagonist activity at human histamine H2 receptor
- ChEMBL_651631 (CHEMBL1228014) Antagonist activity at human histamine H4 receptor
- ChEMBL_659949 (CHEMBL1247350) Binding affinity to human histamine H1 receptor
- ChEMBL_659950 (CHEMBL1247351) Binding affinity to human histamine H2 receptor
- ChEMBL_659951 (CHEMBL1247352) Binding affinity to human histamine H4 receptor
- ChEMBL_664625 (CHEMBL1260339) Binding affinity to rat histamine H3 receptor
- ChEMBL_697524 (CHEMBL1638856) Agonist activity at mouse histamine H4 receptor
- ChEMBL_697525 (CHEMBL1638857) Agonist activity at rat histamine H4 receptor
- ChEMBL_714788 (CHEMBL1663594) Inhibition of guinea pig histamine H1 receptor
- ChEMBL_714789 (CHEMBL1663595) Inhibition of guinea pig histamine H2 receptor
- ChEMBL_741670 (CHEMBL1769662) Binding affinity to human histamine H2 receptor
- ChEMBL_788369 (CHEMBL1918050) Antagonist activity at human histamine H3 receptor
- ChEMBL_788422 (CHEMBL1918187) Antagonist activity at human histamine H3 receptor
- ChEMBL_790540 (CHEMBL1925993) Binding affinity to human histamine H1 receptor
- ChEMBL_790541 (CHEMBL1925994) Binding affinity to human histamine H2 receptor
- ChEMBL_790542 (CHEMBL1925995) Binding affinity to human histamine H4 receptor
- ChEMBL_795783 (CHEMBL1936670) Binding affinity to human histamine H4 receptor
- ChEMBL_795784 (CHEMBL1936671) Binding affinity to rat histamine H4 receptor
- ChEMBL_795795 (CHEMBL1936682) Displacement of [3H]histamine from rat H1R
- ChEMBL_795796 (CHEMBL1936683) Displacement of [3H]histamine from rat H3R
- ChEMBL_795797 (CHEMBL1936684) Displacement of [3H]histamine from rat H4R
- ChEMBL_795798 (CHEMBL1936685) Displacement of [3H]histamine from mouse H1R
- ChEMBL_795799 (CHEMBL1936686) Displacement of [3H]histamine from mouse H3R
- ChEMBL_795961 (CHEMBL1936233) Binding affinity to human histamine H3 receptor
- ChEMBL_795962 (CHEMBL1936234) Binding affinity to rat histamine H3 receptor
- ChEMBL_795963 (CHEMBL1936235) Binding affinity to human histamine H1 receptor
- ChEMBL_795964 (CHEMBL1936236) Binding affinity to human histamine H2 receptor
- ChEMBL_795965 (CHEMBL1936237) Binding affinity to human histamine H4 receptor
- ChEMBL_796037 (CHEMBL1936570) Displacement of [3H]histamine from mouse H4R
- ChEMBL_798253 (CHEMBL1943640) Binding affinity to human histamine H4 receptor
- ChEMBL_798258 (CHEMBL1943645) Binding affinity to human histamine H3 receptor
- ChEMBL_801096 (CHEMBL1948881) Binding affinity to human histamine H3 receptor
- ChEMBL_801097 (CHEMBL1948882) Binding affinity to rat histamine H3 receptor
- ChEMBL_821615 (CHEMBL2038570) Binding affinity to human histamine H2 receptor
- ChEMBL_822394 (CHEMBL2038942) Binding affinity to human histamine H1 receptor
- ChEMBL_822395 (CHEMBL2038943) Binding affinity to human histamine H2 receptor
- ChEMBL_822396 (CHEMBL2038944) Binding affinity to human histamine H4 receptor
- ChEMBL_829172 (CHEMBL2059994) Inhibition of histamine N-methyltransferase by radiochemical assay
- ChEMBL_83644 (CHEMBL693106) Binding affinity to the human histamine H3 receptor
- ChEMBL_83649 (CHEMBL693109) Binding affinity for human histamine H3 receptor
- ChEMBL_84422 (CHEMBL691454) Binding affinity against histamine H1 receptor
- ChEMBL_84544 (CHEMBL697646) Binding affinity against Histamine H1 receptor
- ChEMBL_84556 (CHEMBL692991) Binding affinity for the human Histamine H1 Receptor
- ChEMBL_84865 (CHEMBL694554) Binding affinity towards histamine H1 receptor
- ChEMBL_84868 (CHEMBL694557) Inhibition of mepyramine binding to Histamine H1 receptor
- ChEMBL_84875 (CHEMBL694563) Binding affinity against Histamine H1 receptor
- ChEMBL_84877 (CHEMBL694565) Binding affinity towards histamine H1 receptor
- ChEMBL_853238 (CHEMBL2154939) Binding affinity to human histamine H3 receptor
- ChEMBL_853254 (CHEMBL2154955) Binding affinity to rat histamine H4 receptor
- ChEMBL_853255 (CHEMBL2154956) Binding affinity to human histamine H4 receptor
- ChEMBL_853256 (CHEMBL2154957) Agonist activity at human histamine H4 receptor
- ChEMBL_853257 (CHEMBL2154958) Binding affinity to human histamine H1 receptor
- ChEMBL_85524 (CHEMBL697135) Binding affinity to the human Histamine H2 receptor
- ChEMBL_85661 (CHEMBL702652) Binding affinity for the human Histamine H2 receptor
- ChEMBL_85848 (CHEMBL693575) Binding affinity against Histamine H3 receptor
- ChEMBL_87073 (CHEMBL700590) In vitro binding affinity for Histamine H3 receptor
- ChEMBL_87090 (CHEMBL700768) Binding affinity to the human histamine H4 receptor
- ChEMBL_880232 (CHEMBL2215361) Binding affinity to human histamine H2 receptor
- ChEMBL_880234 (CHEMBL2215363) Binding affinity to human histamine H1 receptor
- ChEMBL_882951 (CHEMBL2209379) Binding affinity to rat histamine H3 receptor
- ChEMBL_955840 (CHEMBL2379697) Binding affinity to mouse histamine H4 receptor
- ChEMBL_955841 (CHEMBL2379698) Binding affinity to rat histamine H4 receptor
- ChEMBL_964768 (CHEMBL2394852) Binding affinity to human histamine H1 receptor
- ChEMBL_983652 (CHEMBL2427307) Inhibition of histamine H2 receptor (unknown origin)
- ChEBML_83828 In vitro antagonistic activity against histamine H3-receptor in an assay with K+-evoked depolarisation-induced release of [3H]histamine of synaptosomes of rat cerebral cortex
- ChEBML_86899 In vitro Histamine H3 receptor antagonist activity in an assay with K+-evoked depolarization-induced release of [3H]histamine from synaptosomes of rat cerebral cortex
- ChEBML_86906 In vitro inhibitory activity against Histamine H3 receptor for K+ evoked depolarization-induced release of [3H]histamine from synaptosomes of rat cerebral cortex
- ChEMBL_1549486 (CHEMBL3755812) Displacement of [3H]histamine from human histamine 4 receptor expressed in HEK293T cell membranes incubated for 1 hr by radioligand binding assay
- ChEMBL_1577462 (CHEMBL3806735) Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cell membrane incubated for 60 mins
- ChEMBL_2034380 (CHEMBL4688538) Displacement of [3H]-Histamine from human histamine 4 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter analysis
- ChEMBL_2034381 (CHEMBL4688539) Displacement of [3H]-Histamine from human histamine 3 receptor transfected in HEK293T cells incubated for 16 hrs by liquid scintillation counter analysis
- ChEMBL_2054928 (CHEMBL4709929) Displacement of [3H]-Histamine from human histamine H3 receptor expressed in Sf9 cells incubated for 60 mins by liquid scintillation counting method
- ChEMBL_452855 (CHEMBL903098) Antagonist activity at histamine H3 receptor in guinea pig ileum assessed as inhibition of (R)-methyl histamine induced longitudinal smooth muscle contraction
- ChEMBL_493054 (CHEMBL953168) Antagonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as inhibition of histamine-induced positive chronotropic activity
- ChEMBL_643318 (CHEMBL1177489) Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting
- ChEMBL_798256 (CHEMBL1943643) Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cells coexpressing Ga15 by radioligand filtration binding assay
- ChEMBL_83647 (CHEMBL693107) Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells
- ChEMBL_83797 (CHEMBL692573) Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells
- ChEMBL_86909 (CHEMBL698419) Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]histamine from rat cerebral cortex synaptosomes
- ChEMBL_957491 (CHEMBL2378229) Displacement of [3H]histamine displacement from human recombinant histamine H4 receptor expressed in SK-NM-C cells after 45 mins
- ChEMBL_750451 (CHEMBL1786003) Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium level increase during phase-1 compound incubated before histamine addition by Fura-2 based fluorometric assay
- ChEMBL_1336219 (CHEMBL3241467) Displacement of [3H]histamine from mouse histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysis
- ChEMBL_1336243 (CHEMBL3241491) Displacement of [3H]histamine from rat histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysis
- ChEMBL_1809276 (CHEMBL4308635) Displacement of [3H]-Histamine from human recombinant histamine H4 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting method
- ChEMBL_1828850 (CHEMBL4328724) Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cell membranes after 30 mins by liquid scintillation analysis
- ChEMBL_83804 (CHEMBL692580) Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor
- ChEMBL_87229 (CHEMBL696449) Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor
- ChEBML_75330 In vitro inhibition of histamine-induced contractions in guinea pig ileum
- ChEBML_87234 Inhibition constant was evaluated against Histamine N-methyl-transferase
- ChEMBL_1282074 (CHEMBL3101863) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1336226 (CHEMBL3241474) Partial agonist activity at mouse histamine H4 receptor
- ChEMBL_1336245 (CHEMBL3241493) Binding affinity to guinea pig histamine H4 receptor
- ChEMBL_1352899 (CHEMBL3269416) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1521513 (CHEMBL3627351) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1521514 (CHEMBL3627352) Binding affinity to histamine H4 receptor (unknown origin)
- ChEMBL_1521712 (CHEMBL3626535) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_1521713 (CHEMBL3626536) Binding affinity to histamine H2 receptor (unknown origin)
- ChEMBL_1521715 (CHEMBL3626538) Binding affinity to guinea pig histamine H4 receptor
- ChEMBL_1539123 (CHEMBL3738631) Binding affinity to histamine H2 receptor (unknown origin)
- ChEMBL_1549487 (CHEMBL3755813) Binding affinity to histamine 4 receptor (unknown origin)
- ChEMBL_1621011 (CHEMBL3863294) Binding affinity to histamine H4 receptor (unknown origin)
- ChEMBL_1621014 (CHEMBL3863297) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_1760112 (CHEMBL4195120) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1789229 (CHEMBL4260963) Antagonist activity at histamine H1 receptor (unknown origin)
- ChEMBL_1908194 (CHEMBL4410552) Antagonist activity at histamine H1 receptor (unknown origin)
- ChEMBL_1979081 (CHEMBL4612216) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1979082 (CHEMBL4612217) Binding affinity to histamine H2 receptor (unknown origin)
- ChEMBL_1979083 (CHEMBL4612218) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_1979084 (CHEMBL4612219) Binding affinity to histamine H4 receptor (unknown origin)
- ChEMBL_2023666 (CHEMBL4677479) Binding affinity to H1 histamine receptor (unknown origin)
- ChEMBL_2112209 (CHEMBL4821059) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_2112210 (CHEMBL4821060) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_2112240 (CHEMBL4821090) Antagonist activity at histamine H3 receptor (unknown origin)
- ChEMBL_2172135 (CHEMBL5057269) Antagonist activity at histamine H3 receptor (unknown origin)
- ChEMBL_2209422 (CHEMBL5122371) Agonist activity at histamine H2 receptor (unknown origin)
- ChEMBL_303340 (CHEMBL840156) Inhibition of [3H]pyrilamine binding to Histamine H1 receptor
- ChEMBL_393875 (CHEMBL912691) Displacement of [3H]histamine form human H4 receptor
- ChEMBL_465005 (CHEMBL948182) Antagonist activity at histamine H1 receptor by FLIPR assay
- ChEMBL_466551 (CHEMBL935643) Displacement of [3H]pyrilamine from histamine H1 receptor
- ChEMBL_466552 (CHEMBL935644) Displacement of [125I]APT from histamine H2 receptor
- ChEMBL_485925 (CHEMBL1013928) Displacement of [3H]pyrilamine from histamine H1 receptor
- ChEMBL_490811 (CHEMBL992748) Binding affinity to human cloned histamine H1 receptor
- ChEMBL_515525 (CHEMBL1036546) Binding affinity to guinea pig histamine H3 receptor
- ChEMBL_624357 (CHEMBL1107887) Antagonist activity at human recombinant histamine 3 receptor
- ChEMBL_640783 (CHEMBL1175775) Binding affinity to histamine H3 receptor in rat brain
- ChEMBL_658559 (CHEMBL1247892) Binding affinity to human recombinant histamine H1 receptor
- ChEMBL_658560 (CHEMBL1247893) Binding affinity to human recombinant histamine H2 receptor
- ChEMBL_658561 (CHEMBL1247894) Binding affinity to human recombinant histamine H3 receptor
- ChEMBL_664372 (CHEMBL1259521) Displacement of [125I]iodoproxyfan human histamine H3 receptor
- ChEMBL_664627 (CHEMBL1260341) Inverse agonist activity at rat histamine H3 receptor
- ChEMBL_664956 (CHEMBL1259913) Binding affinity to guinea pig histamine H1 receptor
- ChEMBL_664957 (CHEMBL1259914) Binding affinity to guinea pig histamine H2 receptor
- ChEMBL_664958 (CHEMBL1259915) Binding affinity to guinea pig histamine H3 receptor
- ChEMBL_664959 (CHEMBL1259916) Binding affinity to guinea pig histamine H4 receptor
- ChEMBL_675954 (CHEMBL1272820) Displacement of [125I]Iodoproxyfan from histamine H3 receptor
- ChEMBL_794973 (CHEMBL1936300) Binding affinity to human cloned histamine H3 receptor
- ChEMBL_83794 (CHEMBL692571) Binding affinity at human cloned Histamine H3 receptor
- ChEMBL_83925 (CHEMBL693690) Binding constant against histamine H1 receptor (in vitro)
- ChEMBL_84427 (CHEMBL691615) Binding affinity towards human histamine H1 receptor
- ChEMBL_84547 (CHEMBL692983) Inhibitory activity against human Histamine H1 receptor
- ChEMBL_84551 (CHEMBL692986) Binding affinity of human cortical histamine H1 receptor
- ChEMBL_84553 (CHEMBL692988) Binding affinity towards human histamine (H1) receptor
- ChEMBL_852846 (CHEMBL2155445) Binding affinity to guinea pig histamine H3 receptor
- ChEMBL_853237 (CHEMBL2154938) Binding affinity to rat cortical histamine H3 receptor
- ChEMBL_853260 (CHEMBL2154961) Binding affinity to rhesus monkey histamine H3 receptor
- ChEMBL_85657 (CHEMBL702649) Binding affinity to the human cortical histamine H2 receptor
- ChEMBL_85659 (CHEMBL702651) Binding affinity towards human histamine (H2) receptor
- ChEMBL_85804 (CHEMBL697082) Binding affinity at human cortical Histamine 1 receptor
- ChEMBL_85805 (CHEMBL697083) Binding affinity at human cortical Histamine 2 receptor
- ChEMBL_85806 (CHEMBL697084) Binding affinity at human cloned Histamine 3 receptor
- ChEMBL_85807 (CHEMBL697085) Binding affinity at rat cortical Histamine 3 receptor
- ChEMBL_86754 (CHEMBL693564) Binding affinity against rat histamine H3 receptor
- ChEMBL_86918 (CHEMBL696919) Binding affinity of compound against Histamine H3 receptor
- ChEMBL_86929 (CHEMBL697538) Binding affinity at rat cortical Histamine H3 receptor
- ChEMBL_86930 (CHEMBL697539) Binding affinity of compound against Histamine H3 receptor
- ChEMBL_86934 (CHEMBL697113) Binding affinity towards rat histamine H3 receptor
- ChEMBL_87054 (CHEMBL697327) Binding affinity for the rat cortical Histamine H3 receptor
- ChEMBL_87062 (CHEMBL698092) Affinity for histamine H3 receptor in rat cerebral cortex.
- ChEMBL_87065 (CHEMBL698254) Binding affinity of compound against Histamine H3 receptor
- ChEMBL_876164 (CHEMBL2183558) Inhibition of radioligand binding to human histamine H1 receptor
- ChEMBL_882945 (CHEMBL2209373) Binding affinity to human recombinant histamine H3 receptor
- ChEMBL_910819 (CHEMBL3058109) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_910821 (CHEMBL3058111) Binding affinity to histamine H2 receptor (unknown origin)
- ChEMBL_975651 (CHEMBL2416135) Binding affinity to histamine H3 receptor (unknown origin)
- ChEMBL_977139 (CHEMBL2416697) Binding affinity to histamine H2 receptor (unknown origin)
- ChEMBL_977140 (CHEMBL2416698) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_986340 (CHEMBL2433831) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_991510 (CHEMBL2445021) Binding affinity to histamine H1 receptor (unknown origin)
- ChEMBL_1336216 (CHEMBL3241464) Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysis
- ChEMBL_1924637 (CHEMBL4427593) Displacement of [3H]histamine from human histamine H3 receptor expressed in Sf9 insect cell membranes after 60 mins by liquid scintillation counting method
- ChEMBL_741663 (CHEMBL1769655) Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular calcium mobilization by FLIPR assay
- ChEMBL_909400 (CHEMBL3057695) Inhibition of H1 receptor in Cavia porcellus Hartley (guinea pig) ileum assessed as inhibition of histamine-induced spasms incubated 2 min prior histamine-challenge
- ChEMBL_1904410 (CHEMBL4406632) Displacement of [3H]-Histamine from recombinant human histamine H4 receptor expressed in HEKT cell membranes measured after 90 mins by microbeta scintillation counting method
- ChEBML_83645 Binding affinity for human histamine H3 receptor on human colon cells
- ChEBML_83769 In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum
- ChEBML_84431 In vitro binding affinity of compound against histamine H1 neuronal receptor
- ChEBML_85525 Binding affinity towards human Histamine H2 receptor (For compound 11)
- ChEBML_86753 Binding affinity for rat histamine H3 receptor on rat cortical cells
- ChEBML_87253 Binding affinity towards rats Histamine type 3 (H3) receptor
- ChEMBL_1274777 (CHEMBL3090316) Binding affinity to human histamine H1 receptor by PDSP assay
- ChEMBL_1455310 (CHEMBL3362674) Antagonist activity at human histamine H1 receptor by luminescence assay
- ChEMBL_1897650 (CHEMBL4399685) Displacement of [3H] pyrilamine from human H1 histamine receptor
- ChEMBL_2329133 Binding affinity at human Histamine H1 receptor assessed as inhibition constant
- ChEMBL_2329134 Binding affinity at human Histamine H3 receptor assessed as inhibition constant
- ChEMBL_302883 (CHEMBL828797) Binding affinity for H1 histamine receptor expressed in CHO cells
- ChEMBL_303185 (CHEMBL829679) Inhibition of [3H]pyrilamine binding to human Histamine H1 receptor
- ChEMBL_305278 (CHEMBL832827) Concentration for 50% inhibition towards central histamine H1 receptor
- ChEMBL_305971 (CHEMBL832957) Inhibition of [3H]pyrilamine binding to human H1 histamine receptor
- ChEMBL_306186 (CHEMBL830980) Inhibition of [125I]aminopotentidine binding to human H2 histamine receptor
- ChEMBL_333055 (CHEMBL853602) Agonist activity at histamine H1 receptor in guinea pig ileum
- ChEMBL_346849 (CHEMBL861839) Binding affinity to histamine H1 receptor by radioligand binding assay
- ChEMBL_346851 (CHEMBL861354) Binding affinity to histamine H2 receptor by radioligand binding assay
- ChEMBL_346879 (CHEMBL861543) Binding affinity to histamine H3 receptor by radioligand binding assay
- ChEMBL_346880 (CHEMBL861544) Binding affinity to histamine H4 receptor by radioligand binding assay
- ChEMBL_539629 (CHEMBL1025634) Displacement of [3H]pyrilamine from human histamine H1 receptor
- ChEMBL_539630 (CHEMBL1025635) Displacement of [3H]tiotidine from human histamine H2 receptor
- ChEMBL_563456 (CHEMBL961004) Binding affinity to histamine H3 receptor in rat cerebral cortex
- ChEMBL_571442 (CHEMBL1032753) Displacement of [3H]SMT from human histamine H3 receptor
- ChEMBL_594567 (CHEMBL1037062) Displacement of [3H]pyrilamine from human histamine H1 receptor
- ChEMBL_604297 (CHEMBL1066753) Displacement of [3H]Pyrilamine from human histamine H1 receptor
- ChEMBL_604298 (CHEMBL1066754) Displacement of [3H]Tiotidine from human histamine H2 receptor
- ChEMBL_664613 (CHEMBL1260327) Displacement of [3H]-RAMH from human histamine H3 receptor
- ChEMBL_747320 (CHEMBL1776623) Antagonist activity at histamine H1 receptor in guinea-pig ileum
- ChEMBL_761538 (CHEMBL1817418) Antagonist activity at histamine H3 receptor in rat cortical membrane
- ChEMBL_767070 (CHEMBL1826119) Displacement of [3H]-NAMH from human histamine H3 receptor
- ChEMBL_767071 (CHEMBL1826120) Displacement of [3H]-NAMH from rat histamine H3 receptor
- ChEMBL_788359 (CHEMBL1918040) Antagonist activity at human histamine H4 receptor by functional assay
- ChEMBL_804714 (CHEMBL1953341) Displacement of [3H]NAMH from rat histamine H3 receptor
- ChEMBL_804715 (CHEMBL1953342) Displacement of [3H]NAMH from human histamine H3 receptor
- ChEMBL_828304 (CHEMBL2050323) Inhibition of histamine H4 receptor-mediated chemotaxis in human eosinophils
- ChEMBL_84251 (CHEMBL696939) Compound was tested for binding affinity against Histamine H1 receptor.
- ChEMBL_84417 (CHEMBL691450) Inhibition of human Histamine H1 receptor using [3H]pyrilamine
- ChEMBL_84552 (CHEMBL692987) Binding affinity towards Histamine H1 receptor of human membranes.
- ChEMBL_85510 (CHEMBL696491) Compound was tested for binding affinity towards Histamine H2 receptor
- ChEMBL_85521 (CHEMBL697132) Inhibition of human Histamine H2 receptor using [3H]tiotidine
- ChEMBL_85812 (CHEMBL878439) Potency against histamine H1 receptor on guinea pig ileum
- ChEMBL_85844 (CHEMBL692952) Antagonistic activity for Histamine H3 receptor binding in guinea pig
- ChEMBL_86904 (CHEMBL698414) In vitro binding affinity against rat histamine H3 receptor
- ChEMBL_86913 (CHEMBL699051) In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.
- ChEMBL_87057 (CHEMBL697959) Binding affinity towards rat cortical Histamine H3 receptor
- ChEMBL_87231 (CHEMBL696451) Binding affinity of compound towards rat histamine H4 receptor
- ChEMBL_87234 (CHEMBL696454) Inhibition constant was evaluated against Histamine N-methyl-transferase
- ChEMBL_883192 (CHEMBL2212118) Binding affinity to rat cerebral cortex histamine H3 receptor
- ChEMBL_911947 (CHEMBL3056387) Antagonist activity at Homo sapiens (human) histamine H4 receptor
- ChEMBL_961000 (CHEMBL2388916) Binding affinity to histamine H3 receptor in rat cortical membranes
- ChEMBL_985420 (CHEMBL2432449) Inhibition of histamine H2 receptor (unknown origin) by PDSP assay
- ChEMBL_985421 (CHEMBL2432450) Inhibition of histamine H1 receptor (unknown origin) by PDSP assay
- ChEBML_1684645 Displacement of [3H]-histamine from human histamine H4R expressed in insect Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillation counting method
- ChEMBL_1577459 (CHEMBL3806732) Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cell membrane incubated for 60 mins by liquid scintillation counting method
- ChEMBL_2085838 (CHEMBL4767101) Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta scintillation counting method
- ChEMBL_2085857 (CHEMBL4767120) Displacement of [3H]-histamine from recombinant mouse histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta scintillation counting method
- ChEMBL_747647 (CHEMBL1777265) Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2 subunit after 60 mins by liquid scintillation counting
- ChEMBL_747649 (CHEMBL1777267) Antagonist activity against histamine H3 receptor in guinea pig ileum assessed as inhibition of electrically-evoked twitches after 30 mins in presence of (R)-alpha-methyl-histamine
- ChEBML_1694103 Displacement of [125I]-aminopotentidine receptor from histamine H2 receptor (unknown origin)
- ChEBML_83771 Inhibition of [3H]mepyramine binding to the Histamine H1 receptor in guinea pig cortex
- ChEBML_83827 Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.
- ChEBML_84246 Inhibition of specific binding of [3H]mepyramine to Histamine 1 receptors in guinea-pig
- ChEBML_84424 Binding affinity towards histamine H1 receptor of human colon cells was determined
- ChEBML_84709 Displacement of [3H]- pyrilamine from rat brain membrane Histamine H1 receptor
- ChEBML_84718 The binding affinity was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.
- ChEBML_85066 In vitro antihistamine activity by activation of 4-methylhistamine mediated by Histamine H2 receptor
- ChEBML_85523 Binding affinity towards histamine H2 receptor of human colon cells was determined
- ChEBML_87091 Binding affinity towards histamine H4 receptor of human colon cells was determined
- ChEMBL_1283829 (CHEMBL3106116) Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)
- ChEMBL_1283830 (CHEMBL3106117) Displacement of [3H]Pyrilamine from histamine H1 receptor (unknown origin)
- ChEMBL_1465389 (CHEMBL3406945) Binding affinity to human histamine H3 receptor expressed in HEK293 cells
- ChEMBL_155859 (CHEMBL768905) Equilibrium binding affinity against histamine-167 residue of phosphoglycerokinase in yeast
- ChEMBL_155860 (CHEMBL768906) Equilibrium binding affinity against histamine-170 residue of phosphoglycerokinase in yeast
- ChEMBL_155861 (CHEMBL768907) Equilibrium binding affinity against histamine-62 residue of phosphoglycerokinase in yeast
- ChEMBL_1837314 (CHEMBL4337447) Displacement of [3H]histamine from human H3R expressed in HEK293T cells
- ChEMBL_2023083 (CHEMBL4676896) Displacement of [3H]nicotine from Histamine H3 receptor (unknown origin)
- ChEMBL_2276501 Antagonist activity at histamine H2 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_2309511 Binding affinity to histamine H2 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_2309512 Binding affinity to histamine H3 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_2325523 Binding affinity to histamine H3 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_2337812 Binding affinity to histamine H4 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_302917 (CHEMBL830377) Binding affinity for human Histamine H1 receptor in CHO K1 cells
- ChEMBL_428742 (CHEMBL916719) Displacement of [3H]pyrilamine from rat cortex histamine H1 receptor
- ChEMBL_436131 (CHEMBL905533) Displacement of [3H]pyrilamine from human cloned histamine H1 receptor
- ChEMBL_481041 (CHEMBL996660) Binding affinity to histamine H3 receptor in guinea pig brain membrane
- ChEMBL_512526 (CHEMBL967016) Displacement of [3H]tiotidine from human cloned histamine H2 receptor
- ChEMBL_534753 (CHEMBL985488) Displacement of [3H]SMT from histamine H3 receptor in forebrain of rat
- ChEMBL_539631 (CHEMBL1025636) Displacement of [3H]alpha-methylhistamine from human histamine H3 receptor
- ChEMBL_563457 (CHEMBL961005) Antagonist activity at histamine H3 receptor in isolated guinea pig ileum
- ChEMBL_563498 (CHEMBL961046) Inhibition of human cloned histamine H1 receptor by competitive binding experiment
- ChEMBL_563499 (CHEMBL961047) Inhibition of human cloned histamine H2 receptor by competitive binding experiment
- ChEMBL_563500 (CHEMBL961048) Inhibition of human cloned histamine H3 receptor by competitive binding experiment
- ChEMBL_577504 (CHEMBL1057856) Binding affinity to human histamine H3 receptor by competitive binding assay
- ChEMBL_577505 (CHEMBL1057857) Binding affinity to rat histamine H3 receptor by competitive binding assay
- ChEMBL_577509 (CHEMBL1057861) Binding affinity to mouse histamine H3 receptor overexpressed in HEK293 cells
- ChEMBL_604299 (CHEMBL1066755) Displacement of [3H]alpha-methylhistamine from human histamine H3 receptor
- ChEMBL_612232 (CHEMBL1074172) Displacement of [3H]Pyrilamine from human cloned histamine H1 receptor
- ChEMBL_612766 (CHEMBL1071592) Displacement of [3H]Nalpha-methylahistamine from human histamine H3 receptor
- ChEMBL_629977 (CHEMBL1112054) Inhibition of human recombinant histamine H4 receptor expressed in CHO cells
- ChEMBL_659491 (CHEMBL1248544) Binding affinity to human histamine H3 receptor by radioligand displacement assay
- ChEMBL_659500 (CHEMBL1248553) Binding affinity to human histamine H1 receptor by radioligand displacement assay
- ChEMBL_659590 (CHEMBL1248885) Binding affinity to human histamine H2 receptor by radioligand displacement assay
- ChEMBL_684912 (CHEMBL1286327) Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor
- ChEMBL_684913 (CHEMBL1286328) Displacement of [125I]APT from human recombinant histamine H2 receptor
- ChEMBL_785249 (CHEMBL1921330) Displacement of [3H]-histamine from rat H4R expressed in HEK293T cells
- ChEMBL_785250 (CHEMBL1921331) Displacement of [3H]-histamine from mouse H4R expressed in HEK293T cells
- ChEMBL_83478 (CHEMBL693949) Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileum
- ChEMBL_83479 (CHEMBL694539) Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileum
- ChEMBL_83645 (CHEMBL878323) Binding affinity for human histamine H3 receptor on human colon cells
- ChEMBL_83772 (CHEMBL693830) Inhibition of [3H]mepyramine binding to the histamine receptor in guinea pig cortex
- ChEMBL_83799 (CHEMBL692575) Histamine H3 receptor competition binding using [3H]Na-methylhistamine
- ChEMBL_84094 (CHEMBL695160) Receptor profile was evaluated at Histamine H1 receptor of guinea pig ileum
- ChEMBL_84426 (CHEMBL691614) Binding affinity towards human Histamine H1 receptor (For compound 11)
- ChEMBL_84698 (CHEMBL692702) Compound tested for its inhibitory activity against Histamine H1 receptor
- ChEMBL_84717 (CHEMBL695165) Inhibition of [3H]pyrilamine binding to Histamine H1 receptor in rat cortex
- ChEMBL_85065 (CHEMBL692776) Inhibitory activity against brain adenylate cyclase Histamine H2 receptor
- ChEMBL_85343 (CHEMBL695017) Receptor profile was evaluated at Histamine H2 receptor of guinea pig atrium
- ChEMBL_85344 (CHEMBL878299) The compound was evaluated for pA2 at Histamine H2 receptor of guinea pig atrium
- ChEMBL_85525 (CHEMBL697136) Binding affinity towards human Histamine H2 receptor (For compound 11)
- ChEMBL_85658 (CHEMBL702650) Binding affinity towards Histamine H2 receptor from human membranes
- ChEMBL_86753 (CHEMBL693563) Binding affinity for rat histamine H3 receptor on rat cortical cells
- ChEMBL_86755 (CHEMBL693565) Binding affinity towards rat Histamine H3 receptor (For compound 11)
- ChEMBL_86760 (CHEMBL698660) Compound was tested for its binding affinity for rat histamine H3 receptor
- ChEMBL_86931 (CHEMBL697540) Binding affinity towards Histamine H3 receptor of rat cortical membranes.
- ChEMBL_87223 (CHEMBL696444) Inhibition of the forskolin-stimulated cAMP production for human Histamine H4 receptor
- ChEMBL_87227 (CHEMBL696447) Histamine H4 receptor competition binding using [3H]Na-methylhistamine
- ChEMBL_87253 (CHEMBL699243) Binding affinity towards rats Histamine type 3 (H3) receptor
- ChEMBL_964196 (CHEMBL2395009) Binding affinity to human histamine H2 receptor by radioligand displacement assay
- ChEMBL_964197 (CHEMBL2395010) Binding affinity to human histamine H1 receptor by radioligand displacement assay
- ChEMBL_966183 (CHEMBL2395688) Binding affinity to human histamine H2 receptor by radioligand displacement assay
- ChEMBL_966185 (CHEMBL2395690) Binding affinity to human histamine H1 receptor by radioligand displacement assay
- ChEMBL_969176 (CHEMBL2404433) Antagonist activity at histamine H1 receptor (unknown origin) by PDSP assay
- ChEMBL_969180 (CHEMBL2404437) Antagonist activity at histamine H2 receptor (unknown origin) by PDSP assay
- ChEMBL_1628378 (CHEMBL3870963) Antagonist activity at human Histamine H3 receptor expressed in CHO cell membranes assessed as inhibition of histamine-induced [35S]GTPgammaS binding after 2 to 6 hrs by scintillation proximity assay
- ChEMBL_2106798 (CHEMBL4815473) Displacement of [3H]histamine from human histamine H4 receptor expressed in sf9 insect cell membranes co-expressing Galphai2/Gbeta1gamma2 incubated for 60 mins by microbeta scintillation counting method
- ChEMBL_1364324 (CHEMBL3293718) Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits after 60 mins by liquid scintillation counting analysis
- ChEMBL_1744234 (CHEMBL4178744) Displacement of [3H]-R(-)-alpha-Methyl[imidazole-2.5(n)]histamine from human recombinant histamine H3 receptor expressed in CHOK1 cell membranes after 1 hr by scintillation counting method
- ChEMBL_741667 (CHEMBL1769659) Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular calcium mobilization at 100 nM after 30 mins by FLIPR assay
- ChEBML_83643 Inhibition of [125I]iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cells
- ChEBML_84432 In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cells
- ChEBML_84708 Compound was evaluated for binding activity against [3H]pyrilamine as radioligand for Histamine H1 receptor
- ChEMBL_1275661 (CHEMBL3090832) Binding affinity to histamine H1 receptor (unknown origin) by radioligand binding assay
- ChEMBL_1365249 (CHEMBL3293214) Displacement of [3H]pyrilamine from human histamine H1 receptor by PDSP assay
- ChEMBL_1550151 (CHEMBL3756492) Binding affinity to histamine H1 receptor (unknown origin) by competition binding assay
- ChEMBL_1550152 (CHEMBL3756493) Binding affinity to histamine H3 receptor (unknown origin) by competition binding assay
- ChEMBL_1557340 (CHEMBL3774024) Binding affinity to histamine H2 receptor (unknown origin) by radioligand binding assay
- ChEMBL_2196600 (CHEMBL5109116) Binding affinity to histamine H1 receptor (unknown origin) assessed as inhibition constant
- ChEMBL_361012 (CHEMBL862625) Binding affinity to human cloned histamine H1 receptor by radioligand binding assay
- ChEMBL_385815 (CHEMBL870339) Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranes
- ChEMBL_429753 (CHEMBL914453) Displacement of [3H]ketanserin from histamine H2 receptor in human cortex membranes
- ChEMBL_435556 (CHEMBL903915) Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membranes
- ChEMBL_435623 (CHEMBL903980) Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membrane
- ChEMBL_438819 (CHEMBL887977) Inverse agonist activity at human histamine H3 receptor by GTP gammaS assay
- ChEMBL_464862 (CHEMBL930579) Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells
- ChEMBL_464863 (CHEMBL930580) Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes
- ChEMBL_468943 (CHEMBL930591) Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex
- ChEMBL_534751 (CHEMBL985486) Displacement of [125I]-APT from histamine H2 receptor in brain of guinea pig
- ChEMBL_558570 (CHEMBL959899) Displacement of [3H]pyrilamine from histamine H1 receptor in guinea pig cerebellum
- ChEMBL_577512 (CHEMBL1057864) Binding affinity to histamine H3 receptor in wild type mouse brain membrane
- ChEMBL_584028 (CHEMBL1055908) Inhibition of human histamine H3 expressed in CHO cells by saturation binding experiment
- ChEMBL_629740 (CHEMBL1121100) Agonist activity at histamine H2 receptor in spontaneously beating guinea pig atrium
- ChEMBL_695346 (CHEMBL1638883) Agonist activity at rat histamine H4 receptor by luciferase reporter gene assay
- ChEMBL_697535 (CHEMBL1639032) Agonist activity at mouse histamine H4 receptor by luciferase reporter gene assay
- ChEMBL_768665 (CHEMBL1832772) Antagonist activity at human histamine 3 receptor by [35S]GTPgammaS binding assay
- ChEMBL_785248 (CHEMBL1921329) Displacement of [3H]-histamine from guinea pig H4R expressed in HEK293T cells
- ChEMBL_818296 (CHEMBL2034344) Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor
- ChEMBL_828305 (CHEMBL2050324) Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cells
- ChEMBL_83477 (CHEMBL693948) Potency at histamine H3 receptor subtype, was tested on guinea pig right ileum
- ChEMBL_83634 (CHEMBL695764) Inhibition of human H3-receptor using [3H]N-alpha-methyl histamine
- ChEMBL_83648 (CHEMBL693108) Compound was tested for its binding affinity against human histamine H3 receptor
- ChEMBL_83827 (CHEMBL691844) Evaluated for antagonist activity against histamine H3 receptor and is represented as -log Ki.
- ChEMBL_83830 (CHEMBL692771) In vitro antagonistic activity against histamine H3 receptor on rat cerebral cortex
- ChEMBL_84093 (CHEMBL695159) Potency at histamine H1 receptor subtype, was tested on guinea pig right ileum
- ChEMBL_84701 (CHEMBL692705) Inhibitory binding of [3H]mepyramine to histamine H1 receptors in rat brain membranes
- ChEMBL_84709 (CHEMBL694448) Displacement of [3H]- pyrilamine from rat brain membrane Histamine H1 receptor
- ChEMBL_84718 (CHEMBL695166) The binding affinity was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.
- ChEMBL_853249 (CHEMBL2154950) Inverse agonist activity at human histamine H3 receptor by GTPgammaS binding assay
- ChEMBL_85342 (CHEMBL695016) Potency at histamine H2 receptor subtype, was tested on guinea pig right atrium
- ChEMBL_86900 (CHEMBL698410) In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortex
- ChEMBL_910820 (CHEMBL3058110) Binding affinity to histamine H3 receptor in Cavia porcellus (guinea pig) ileum
- ChEMBL_964770 (CHEMBL2394854) Displacement of [3H]N-alpha-methylhistamine from rat histamine H3 receptor
- ChEMBL_986995 (CHEMBL2439315) Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileum
- ChEMBL_2237563 (CHEMBL5151459) Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 and G-beta1gamma2 incubated for 60 mins by scintillation counting analysis
- ChEMBL_793260 (CHEMBL1931709) Antagonist activity at histamine H3 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamine-induced cAMP accumulation after 5 hrs by luciferase reporter gene assay
- ChEMBL_793266 (CHEMBL1931715) Antagonist activity at histamine H4 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamine-induced cAMP accumulation after 5 hrs by luciferase reporter gene assay
- ChEBML_84867 Compound was tested for the binding affinity against histamine H1 receptor by using [3H]mepyramine as radioligand
- ChEBML_85670 Compound was tested for in vitro inhibition of the binding of [125I](Nle11)-HG-13 to Histamine H2 receptor
- ChEBML_85683 Affinity to the Histamine H2 receptor was determined expressed in CHO cell using [125I]iodoaminopotentidine as radioligand
- ChEBML_85684 Inhibitory activity against binding of [125I](Nle11)-HG-13 to Histamine H2 receptor in vitro
- ChEBML_85851 Inhibition of N-alpha-methylhistamine binding to histamine H3 receptor of guinea pig brain membranes
- ChEBML_86910 The binding affinity was measured on histamine H3 receptor using [3H]- N-Me-histam as radioligand.
- ChEMBL_1293783 (CHEMBL3123355) Displacement of [3H]NAMH from rat histamine H3 receptor transfected in CHO cells
- ChEMBL_1361673 (CHEMBL3291570) Binding affinity to human histamine H2 receptor at 10 uM by radioligand displacement assay
- ChEMBL_1361675 (CHEMBL3291572) Binding affinity to human histamine H4 receptor at 10 uM by radioligand displacement assay
- ChEMBL_1452250 (CHEMBL3366162) Displacement of [3H]Pyrilamine from human histamine H1 receptor by liquid scintillation counting
- ChEMBL_1549942 (CHEMBL3755089) Displacement of [3H]R-alpha-methyl histamine from recombinant human H3 receptor
- ChEMBL_1923563 (CHEMBL4426519) Binding affinity to human H1 histamine receptor expressed in HEK cells by PDSP assay
- ChEMBL_1973789 (CHEMBL4606607) Displacement of [3H]-histamine from human recombinant H4R expressed in HEK293T cell homogenates
- ChEMBL_302919 (CHEMBL830379) Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cells
- ChEMBL_303089 (CHEMBL828761) Binding affinity for recombinant human Histamine H1 receptor expressed in CHO K1 cells
- ChEMBL_327756 (CHEMBL861797) Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in human brain
- ChEMBL_334179 (CHEMBL866473) Displacement of [3H]N-alpha-methylhistamine from guinea pig histamine H3 receptor
- ChEMBL_346130 (CHEMBL862327) Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells
- ChEMBL_360161 (CHEMBL871260) Antagonist activity at human histamine H3 receptor by [35S]GTP-gamma-S assay
- ChEMBL_422153 (CHEMBL713681) Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assay
- ChEMBL_429751 (CHEMBL914451) Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes
- ChEMBL_464866 (CHEMBL931756) Antagonist activity at histamine H1 receptor by [35S]GTP-gamma-S binding assay
- ChEMBL_464867 (CHEMBL931757) Antagonist activity at histamine H2 receptor by [35S]GTP-gamma-S binding assay
- ChEMBL_464868 (CHEMBL931758) Antagonist activity at histamine H4 receptor by [35S]GTP-gamma-S binding assay
- ChEMBL_475721 (CHEMBL934607) Displacement of [3H]mepyramine from human histamine H1 receptor expressed in NIH3T3 cells
- ChEMBL_489537 (CHEMBL986460) Displacement of [3H]RAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_491618 (CHEMBL945389) Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane
- ChEMBL_501237 (CHEMBL975272) Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cells
- ChEMBL_536770 (CHEMBL984564) Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane
- ChEMBL_537264 (CHEMBL982707) Displacement of [3H]N-alpha-methylhistamine from mouse recombinant histamine H3 receptor
- ChEMBL_540493 (CHEMBL1030597) Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cells
- ChEMBL_556997 (CHEMBL958183) Displacement of [3H]mepyramine from human histamine H1 receptor expressed in NIH3T3 cells
- ChEMBL_563455 (CHEMBL961003) Displacement of [125I]Iodoproxyfran from human histamine H3 receptor expressed in HEK293 cells
- ChEMBL_583250 (CHEMBL1055805) Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane
- ChEMBL_591576 (CHEMBL1042329) Displacement of [3H]N-alpha-methylhistamine from mouse brain histamine H3 receptor
- ChEMBL_619281 (CHEMBL1100661) Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in HEK293 cells
- ChEMBL_621968 (CHEMBL1104110) Displacement of [3H]mepyramine from human histamine H1 receptor expressed in Sf9 cells
- ChEMBL_621969 (CHEMBL1104111) Displacement of [3H]tiotidine from human histamine H2 receptor expressed in Sf9 cells
- ChEMBL_634304 (CHEMBL1120717) Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor
- ChEMBL_634305 (CHEMBL1120718) Displacement of [3H]N-alpha-methylhistamine from rat cloned histamine H3 receptor
- ChEMBL_652205 (CHEMBL1228478) Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain
- ChEMBL_664249 (CHEMBL1261756) Displacement of [125I]Iodoproxyfan from human histamine H3 receptor expressed in HEK293 cells
- ChEMBL_664250 (CHEMBL1261757) Displacement of [3H]Methylhistamine from human histamine H3 receptor expressed in HEK293 cells
- ChEMBL_697510 (CHEMBL1638842) Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cells
- ChEMBL_761528 (CHEMBL1817408) Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_761529 (CHEMBL1817409) Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_772494 (CHEMBL1839285) Displacement of [3H]-NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_772497 (CHEMBL1839389) Displacement of [3H]-NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_785117 (CHEMBL1920855) Displacement of [3H]-histamine from full length human H4R expressed in HEK293 cells
- ChEMBL_785242 (CHEMBL1921323) Antagonist activity at H4R in human eosinophils assessed as inhibition of histamine-induced CD11b upregulation
- ChEMBL_785243 (CHEMBL1921324) Antagonist activity at H4R in human eosinophils assessed as inhibition of histamine-induced actin polymerisation
- ChEMBL_790538 (CHEMBL1925991) Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_790539 (CHEMBL1925992) Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_794859 (CHEMBL1936095) Displacement of N-[3H]-methylhistamine from histamine H3 receptor in rat cortex membranes
- ChEMBL_795468 (CHEMBL1937473) Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_795469 (CHEMBL1937474) Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_795470 (CHEMBL1937475) Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assay
- ChEMBL_795785 (CHEMBL1936672) Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes
- ChEMBL_795791 (CHEMBL1936678) Displacement of [3H]histamine from human H3 receptor expressed in HEK cell membranes
- ChEMBL_795792 (CHEMBL1936679) Displacement of [3H]histamine from human H1 receptor expressed in HEK cell membranes
- ChEMBL_802314 (CHEMBL1949472) Displacement of [3H]-Pyrilamine from human histamine H1 receptor by liquid scintillation counter
- ChEMBL_804457 (CHEMBL1952467) Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_804458 (CHEMBL1952468) Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_820600 (CHEMBL2040489) Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells
- ChEMBL_820601 (CHEMBL2040490) Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells
- ChEMBL_820614 (CHEMBL2040503) Inverse agonist activity at human histamine H3 receptor by [35S]-GTPgammaS binding assay
- ChEMBL_820697 (CHEMBL2037968) Displacement of [3H]Pyrilamine from human H1 histamine receptor by liquid scintillation assay
- ChEMBL_83651 (CHEMBL693111) Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressing CHO cells
- ChEMBL_83802 (CHEMBL692578) Compound was tested for its binding affinity towards rat cortical Histamine H3L receptor
- ChEMBL_83825 (CHEMBL691842) Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex
- ChEMBL_83929 (CHEMBL693694) Inhibition of the specific binding of [3H]pyrilamine to guinea pig cerebellum histamine H1 receptor
- ChEMBL_84111 (CHEMBL699475) H1-Histamine receptor agonism on Guinea pig aorta was evaluated (SEM 0.03-0.18)
- ChEMBL_84428 (CHEMBL691616) Binding affinity for recombinant human Histamine H1 receptor using [3H]pyrilamine as radioligand.
- ChEMBL_84708 (CHEMBL694447) Compound was evaluated for binding activity against [3H]pyrilamine as radioligand for Histamine H1 receptor
- ChEMBL_85512 (CHEMBL696493) Inhibition of [125I]APT binding to histamine H2 receptor in guinea pig cerebral membranes.
- ChEMBL_85526 (CHEMBL697137) Binding affinity towards human Histamine H2 receptor, using [3H]tiotidine as radioligand.
- ChEMBL_85653 (CHEMBL702004) Binding affinity for recombinant human Histamine H2 receptor using [3H]tiotidine as radioligand.
- ChEMBL_85823 (CHEMBL697662) In vitro antagonistic activity against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.
- ChEMBL_85826 (CHEMBL697664) Antagonistic activity for Histamine H3 receptor on electrically evoked guinea-pig ileum contraction
- ChEMBL_861829 (CHEMBL2173422) Inhibition of SYK in human basophils assessed as reduction in anti-IgE-stimulated histamine release
- ChEMBL_86764 (CHEMBL698664) Evaluated for antagonistic activity at histamine H3 receptor in rat cerebral cortex and is represented as Ki
- ChEMBL_86895 (CHEMBL698405) Evaluated for antagonistic activity at histamine H3 receptor in rat cerebral cortex and is represented as Ki.
- ChEMBL_86902 (CHEMBL698412) In vitro antagonistic activity against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.
- ChEMBL_87060 (CHEMBL698090) In vitro binding affinity was measured against Histamine H3 receptor on rat cerebral cortex.
- ChEMBL_793261 (CHEMBL1931710) Inverse agonist activity at histamine H3 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamine-induced cAMP accumulation after 5 hrs by luciferase reporter gene assay
- ChEBML_1690614 Displacement of [3H]Histamine from human H4 receptor after 90 mins by scintillation counting method
- ChEBML_84421 Ability to displace [3H]pyrilamine from human cloned histamine H1 receptor expressed in CHO cells
- ChEBML_84706 Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand
- ChEBML_85849 Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membrane
- ChEBML_86751 Binding affinity to rat Histamine H3 receptor in CHO-K1 cells using [125I]iodoproxyfan as radioligand
- ChEMBL_1522875 (CHEMBL3630593) Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contraction
- ChEMBL_1753243 (CHEMBL4188003) Antagonistic activity at histamine 1 receptor (unknown origin) after 10 mins by FLIPR assay
- ChEMBL_1837312 (CHEMBL4337445) Displacement of [3H]histamine from human H3R expressed in human SK-N-MC-cells
- ChEMBL_1870427 (CHEMBL4371594) Agonist activity at histamine H4 receptor (unknown origin) assessed as increase in beta-arrestin recruitment
- ChEMBL_304064 (CHEMBL839739) Displacement of [125I]aminopotentidine binding to CHO cell membranes expressing human histamine H2 receptor
- ChEMBL_327753 (CHEMBL861794) Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in guinea pig brain
- ChEMBL_327757 (CHEMBL861798) Displacement of [3H]N-alpha-methylhistamine from histamine H1 receptor in guinea pig brain
- ChEMBL_463102 (CHEMBL930008) Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane
- ChEMBL_499924 (CHEMBL979834) Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cells
- ChEMBL_540492 (CHEMBL1030596) Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cells
- ChEMBL_562964 (CHEMBL1015363) Agonist activity at histamine H2 receptor in guinea pig atrium assessed as increase in heart rate
- ChEMBL_583253 (CHEMBL1055808) Inverse agonist activity against human histamine H3 receptor by [35S]GTPgamma binding assay
- ChEMBL_619278 (CHEMBL1100658) Displacement of [3H]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells
- ChEMBL_665661 (CHEMBL1261592) Displacement of [3H]prozosin from human cloned histamine H1 receptor expressed in CHO cells
- ChEMBL_685205 (CHEMBL1287093) Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay
- ChEMBL_749355 (CHEMBL1785145) Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical hemispheres
- ChEMBL_766631 (CHEMBL1827197) Inverse agonist activity at human histamine H3 receptor expressed in SK-N-MC cells
- ChEMBL_766669 (CHEMBL1827363) Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay
- ChEMBL_768592 (CHEMBL1832611) Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cells
- ChEMBL_768593 (CHEMBL1832612) Displacement of [3H]NAMH from rat cloned histamine 3 receptor expressed in CHO cells
- ChEMBL_794974 (CHEMBL1936301) Inverse agonist activity at human cloned histamine H3 receptor by [35S]GTPgammaS binding assay
- ChEMBL_815276 (CHEMBL2026491) Displacement of [125H]iodoproxyphan from human histamine H3 receptor expressed in CHO-K1 cells
- ChEMBL_84707 (CHEMBL694446) Binding affinity towards rat histamine H1 receptor was determined using [3H]pyrilamine as radioligand
- ChEMBL_86733 (CHEMBL693458) In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex
- ChEMBL_86737 (CHEMBL693462) In vitro intrinsic activity against histamine H3 receptor from synaptosomes of rat cerebral cortex
- ChEMBL_86905 (CHEMBL698415) In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortex
- ChEMBL_86910 (CHEMBL698420) The binding affinity was measured on histamine H3 receptor using [3H]- N-Me-histam as radioligand.
- ChEMBL_882946 (CHEMBL2209374) Binding affinity to rat brain histamine H3 receptor after 1 hr by gamma counting
- ChEMBL_975652 (CHEMBL2416136) Displacement of [125I]iodoproxyfan from histamine H3 receptor (unknown origin) expressed in CHO cells
- ChEMBL_977021 (CHEMBL2416545) Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells