OSELTAMIVIR POTTASIUM CARBOXYLATE BDBM50484773 Oseltamivir Potassium Carboxylate
Guanidino-Oseltamivir Carboxylicacid BDBM50028503 CHEMBL81717
BDBM5025 Oseltamivir ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate US10919856, POSITIVE CONTROL
GS4071 Oseltamivir carboxylate BDBM4994 CHEMBL674 (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
US9527857, M BDBM253921 US9464092, M
BDBM204122 US9539260, M US9763952, Example M
BDBM256611 US9790174, Example 85(m) US10435361, Example 85(m) US9481648, 85(m)
US11267820, Compound m US10689395, Compound m BDBM448086
1,3-xylene 1,3-Dimethylbenzol m-methyltoluene BDBM50008556 m-xylene CHEMBL286727 m-Xylol 3-xylene meta-xylene m-dimethylbenzene
- Hoffmann, G; Funk, C; Fowler, S; Otteneder, MB; Breidenbach, A; Rayner, CR; Chu, T; Prinssen, EP Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system. Antimicrob Agents Chemother 53: 4753-61 (2009)
- Cheng, TJ; Weinheimer, S; Tarbet, EB; Jan, JT; Cheng, YS; Shie, JJ; Chen, CL; Chen, CA; Hsieh, WC; Huang, PW; Lin, WH; Wang, SY; Fang, JM; Hu, OY; Wong, CH Development of oseltamivir phosphonate congeners as anti-influenza agents. J Med Chem 55: 8657-70 (2012)
- Liu, KC; Lee, PS; Wang, SY; Cheng, YS; Fang, JM; Wong, CH Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir. Bioorg Med Chem 19: 4796-802 (2011)
- Hata, K; Koseki, K; Yamaguchi, K; Moriya, S; Suzuki, Y; Yingsakmongkon, S; Hirai, G; Sodeoka, M; von Itzstein, M; Miyagi, T Limited inhibitory effects of oseltamivir and zanamivir on human sialidases. Antimicrob Agents Chemother 52: 3484-91 (2008)
- Hong, BT; Chen, CL; Fang, JM; Tsai, KC; Wang, SY; Huang, WI; Cheng, YS; Wong, CH Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors. Bioorg Med Chem 22: 6647-54 (2015)
- Zhang, J; Murugan, NA; Tian, Y; Bertagnin, C; Fang, Z; Kang, D; Kong, X; Jia, H; Sun, Z; Jia, R; Gao, P; Poongavanam, V; Loregian, A; Xu, W; Ma, X; Ding, X; Huang, B; Zhan, P; Liu, X Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant. J Med Chem 61: 9976-9999 (2018)
- Zhao, H; Jiang, S; Ye, Z; Zhu, H; Hu, B; Meng, P; Hu, Y; Zhang, H; Wang, K; Wang, J; Tian, Y Discovery of hydrazide-containing oseltamivir analogues as potent inhibitors of influenza A neuraminidase. Eur J Med Chem 221: (2021)
- Gaisina, IN; Peet, NP; Cheng, H; Li, P; Du, R; Cui, Q; Furlong, K; Manicassamy, B; Caffrey, M; Thatcher, GRJ; Rong, L Optimization of 4-Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir. J Med Chem 63: 3120-3130 (2020)
- Mooney, CA; Johnson, SA; 't Hart, P; Quarles van Ufford, L; de Haan, CA; Moret, EE; Martin, NI Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors. J Med Chem 57: 3154-60 (2014)
- Wang, Z; Cheng, LP; Zhang, XH; Pang, W; Li, L; Zhao, JL Design, synthesis and biological evaluation of novel oseltamivir derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett 27: 5429-5435 (2017)
- Ju, H; Zhang, J; Sun, Z; Huang, Z; Qi, W; Huang, B; Zhan, P; Liu, X Discovery of C-1 modified oseltamivir derivatives as potent influenza neuraminidase inhibitors. Eur J Med Chem 146: 220-231 (2018)
- Wang, K; Zhang, H; Tian, Y The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A?A review. Eur J Med Chem 243: (2022)
- Hsu, PH; Chiu, DC; Wu, KL; Lee, PS; Jan, JT; Cheng, YE; Tsai, KC; Cheng, TJ; Fang, JM Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses. Eur J Med Chem 154: 314-323 (2018)
- Wang, B; Wang, K; Meng, P; Hu, Y; Yang, F; Liu, K; Lei, Z; Chen, B; Tian, Y Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors. Bioorg Med Chem Lett 28: 3477-3482 (2018)
- Schade, D; Kotthaus, J; Riebling, L; Kotthaus, J; Müller-Fielitz, H; Raasch, W; Koch, O; Seidel, N; Schmidtke, M; Clement, B Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A. J Med Chem 57: 759-69 (2014)
- Xie, Y; Xu, D; Huang, B; Ma, X; Qi, W; Shi, F; Liu, X; Zhang, Y; Xu, W Discovery of N-substituted oseltamivir derivatives as potent and selective inhibitors of H5N1 influenza neuraminidase. J Med Chem 57: 8445-58 (2014)
- Zhao, X; Li, R; Zhou, Y; Xiao, M; Ma, C; Yang, Z; Zeng, S; Du, Q; Yang, C; Jiang, H; Hu, Y; Wang, K; Mok, CKP; Sun, P; Dong, J; Cui, W; Wang, J; Tu, Y; Yang, Z; Hu, W Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses. J Med Chem 61: 5187-5198 (2018)
- Hong, BT; Cheng, YE; Cheng, TJ; Fang, JM Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: Synthesis and anti-influenza activity. Eur J Med Chem 163: 710-721 (2019)
- Wang, K; Lei, Z; Zhao, L; Chen, B; Yang, F; Liu, K; Zhu, H; Zhao, H; Cao, R; Zhang, K; Tian, Y Design, synthesis and biological evaluation of oseltamivir derivatives containing pyridyl group as potent inhibitors of neuraminidase for influenza A. Eur J Med Chem 185: (2020)
- Ju, H; Xiu, S; Ding, X; Shang, M; Jia, R; Huang, B; Zhan, P; Liu, X Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem 187: (2020)
- Albohy, A; Mohan, S; Zheng, RB; Pinto, BM; Cairo, CW Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes. Bioorg Med Chem 19: 2817-22 (2011)
- Ju, H; Hou, L; Zhao, F; Zhang, Y; Jia, R; Guizzo, L; Bonomini, A; Zhang, J; Gao, Z; Liang, R; Bertagnin, C; Kong, X; Ma, X; Kang, D; Loregian, A; Huang, B; Liu, X; Zhan, P Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors J Med Chem 65: 11550-11573 (2022)
- Govorkova, EA; Ilyushina, NA; McClaren, JL; Naipospos, TS; Douangngeun, B; Webster, RG Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model. Antimicrob Agents Chemother 53: 3088-96 (2009)
- Boechat, Fda C; Sacramento, CQ; Cunha, AC; Sagrillo, FS; Nogueira, CM; Fintelman-Rodrigues, N; Santos-Filho, O; Riscado, CS; Forezi, Lda S; Faro, LV; Brozeguini, L; Marques, IP; Ferreira, VF; Souza, TM; de Souza, MC 1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses. Bioorg Med Chem 23: 7777-84 (2015)
- Hu, Y; Chen, X; Smith, DE Species-dependent uptake of glycylsarcosine but not oseltamivir in Pichia pastoris expressing the rat, mouse, and human intestinal peptide transporter PEPT1. Drug Metab Dispos 40: 1328-35 (2012)
- Jia, R; Zhang, J; Shi, F; Bonomini, A; Lucca, C; Bertagnin, C; Zhang, J; Liu, C; Jia, H; Jiang, Y; Ma, X; Loregian, A; Huang, B; Zhan, P; Liu, X Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties. Eur J Med Chem 252: (2023)
- Zhang, J; Poongavanam, V; Kang, D; Bertagnin, C; Lu, H; Kong, X; Ju, H; Lu, X; Gao, P; Tian, Y; Jia, H; Desta, S; Ding, X; Sun, L; Fang, Z; Huang, B; Liang, X; Jia, R; Ma, X; Xu, W; Murugan, NA; Loregian, A; Huang, B; Zhan, P; Liu, X Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant. J Med Chem 61: 6379-6397 (2018)
- Mohan, S; McAtamney, S; Haselhorst, T; von Itzstein, M; Pinto, BM Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles. J Med Chem 53: 7377-91 (2010)
- Ye, J; Yang, X; Xu, M; Chan, PK; Ma, C Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies. Eur J Med Chem 182: (2019)
- Poudel, YB; He, L; Cox, M; Zhang, Q; Johnson, WL; Cong, Q; Cheng, H; Chowdari, NS; Tarby, C; Donnell, AF; Broekema, M; O'Malley, DP; Zhang, Y; A M Subbaiah, M; Kumar, BV; Subramani, L; Wang, B; Li, YX; Sivaprakasam, P; Critton, D; Mulligan, D; Sandhu, B; Xie, C; Ramakrishnan, R; Nagar, J; Dudhgaonkar, S; Oderinde, MS; Murtaza, A; Schieven, GL; Mathur, A; Gavai, AV; Vite, G; Gangwar, S ACS Med Chem Lett 15: 181-188 (2024)
- Hedner, E; Sjögren, M; Frändberg, PA; Johansson, T; Göransson, U; Dahlström, M; Jonsson, P; Nyberg, F; Bohlin, L J Nat Prod 69: 1421-4 (2006)
- Lehtiö, L; Jemth, AS; Collins, R; Loseva, O; Johansson, A; Markova, N; Hammarström, M; Flores, A; Holmberg-Schiavone, L; Weigelt, J; Helleday, T; Schüler, H; Karlberg, T J Med Chem 52: 3108-11 (2009)
- Delouvrié, B; Al-Kadhimi, K; Arnould, JC; Barry, ST; Cross, DA; Didelot, M; Gavine, PR; Germain, H; Harris, CS; Hughes, AM; Jude, DA; Kendrew, J; Lambert-van der Brempt, C; Lohmann, JJ; Ménard, M; Mortlock, AA; Pass, M; Rooney, C; Vautier, M; Vincent, JL; Warin, N Bioorg Med Chem Lett 22: 4111-6 (2012)
- Dannhardt, G; Plutizki, S; Kramb, J; Müller, A; Möhler, M US Patent US9364459 (2016)
- Vasbinder, MM; Aquila, B; Augustin, M; Chen, H; Cheung, T; Cook, D; Drew, L; Fauber, BP; Glossop, S; Grondine, M; Hennessy, E; Johannes, J; Lee, S; Lyne, P; Mörtl, M; Omer, C; Palakurthi, S; Pontz, T; Read, J; Sha, L; Shen, M; Steinbacher, S; Wang, H; Wu, A; Ye, M J Med Chem 56: 1996-2015 (2013)
- Scott, WJ; Liu, N; Möwes, M; Hägebarth, A; Mönning, U; Bömer, U US Patent US8895549 (2014)
- Traxler, P; Trinks, U; Buchdunger, E; Mett, H; Meyer, T; Müller, M; Regenass, U; Rösel, J; Lydon, N J Med Chem 38: 2441-8 (1995)
- Brauers, G; Edrada, RA; Ebel, R; Proksch, P; Wray, V; Berg, A; Gräfe, U; Schächtele, C; Totzke, F; Finkenzeller, G; Marme, D; Kraus, J; Münchbach, M; Michel, M; Bringmann, G; Schaumann, K J Nat Prod 63: 739-45 (2000)
- Volgraf, M; Lumb, JP; Brastianos, HC; Carr, G; Chung, MK; Münzel, M; Mauk, AG; Andersen, RJ; Trauner, D Nat Chem Biol 4: 535-7 (2008)
- Ahlström, MM; Ridderström, M; Zamora, I J Med Chem 50: 5382-91 (2007)
- Fedorov, O; Marsden, B; Pogacic, V; Rellos, P; Müller, S; Bullock, AN; Schwaller, J; Sundström, M; Knapp, S Proc Natl Acad Sci U S A 104: 20523-8 (2007)
- Jin, J; An, M; Sapienza, A; Aiyar, N; Naselsky, D; Sarau, HM; Foley, JJ; Salyers, KL; Knight, SD; Keenan, RM; Rivero, RA; Dhanak, D; Douglas, SA Bioorg Med Chem Lett 18: 3950-4 (2008)
- Hidaka, K; Kimura, T; Sankaranarayanan, R; Wang, J; McDaniel, KF; Kempf, DJ; Kameoka, M; Adachi, M; Kuroki, R; Nguyen, JT; Hayashi, Y; Kiso, Y J Med Chem 61: 5138-5153 (2018)
- Helal, CJ; Sanner, MA; Cooper, CB; Gant, T; Adam, M; Lucas, JC; Kang, Z; Kupchinsky, S; Ahlijanian, MK; Tate, B; Menniti, FS; Kelly, K; Peterson, M Bioorg Med Chem Lett 14: 5521-5 (2004)
- Lin, R; Connolly, PJ; Lu, Y; Chiu, G; Li, S; Yu, Y; Huang, S; Li, X; Emanuel, SL; Middleton, SA; Gruninger, RH; Adams, M; Fuentes-Pesquera, AR; Greenberger, LM Bioorg Med Chem Lett 17: 4297-302 (2007)
- Adler, M; Davey, DD; Phillips, GB; Kim, SH; Jancarik, J; Rumennik, G; Light, DR; Whitlow, M Biochemistry 39: 12534-42 (2000)
- Adonias, M; Anayaba, J; Cámara, J; Canet, E; Gateau-Olesker, A; Gero, SD; Grande, M; Hernando, JI Bioorg Med Chem Lett 3: 2547-2552 (1993)
- Campestre, C; Tortorella, P; Agamennone, M; Preziuso, S; Biasone, A; Nuti, E; Rossello, A; Gallina, C Eur J Med Chem 43: 1008-14 (2008)
- Hen, N; Bialer, M; Yagen, B; Maresca, A; Aggarwal, M; Robbins, AH; McKenna, R; Scozzafava, A; Supuran, CT J Med Chem 54: 3977-81 (2011)
- Louvel, J; Guo, D; Agliardi, M; Mocking, TA; Kars, R; Pham, TP; Xia, L; de Vries, H; Brussee, J; Heitman, LH; Ijzerman, AP J Med Chem 57: 3213-22 (2014)
- Bargota, RS; Akhtar, M; Biggadike, K; Gani, D; Allemann, RK Bioorg Med Chem Lett 13: 1623-6 (2003)
- Yamaguchi, M; Kamei, K; Koga, T; Akima, M; Maruyama, A; Kuroki, T; Ohi, N J Med Chem 36: 4061-8 (1994)
- Muralidharan, VP; Alagumuthu, M; Iyer, SK Bioorg Med Chem Lett 27: 2510-2514 (2017)
- Chen, P; Cheng, PT; Alam, M; Beyer, BD; Bisacchi, GS; Dejneka, T; Evans, AJ; Greytok, JA; Hermsmeier, MA; Humphreys, WG; Jacobs, GA; Kocy, O; Lin, PF; Lis, KA; Marella, MA; Ryono, DE; Sheaffer, AK; Spergel, SH; Sun, CQ; Tino, JA; Vite, G; Colonno, RJ; Zahler, R; Barrish, JC J Med Chem 39: 1991-2007 (1996)
- Lawson, M; Rodrigo, J; Baratte, B; Robert, T; Delehouzé, C; Lozach, O; Ruchaud, S; Bach, S; Brion, JD; Alami, M; Hamze, A Eur J Med Chem 123: 105-114 (2016)
- Tanis, VM; Venkatesan, H; Cummings, MD; Albers, M; Kent Barbay, J; Herman, K; Kummer, DA; Milligan, C; Nelen, MI; Nishimura, R; Schlueter, T; Scott, B; Spurlino, J; Wolin, R; Woods, C; Xue, X; Edwards, JP; Fourie, AM; Leonard, K Bioorg Med Chem Lett 29: 1463-1470 (2019)
- Taha, M; Ismail, NH; Imran, S; Selvaraj, M; Rahim, A; Ali, M; Siddiqui, S; Rahim, F; Khan, KM Bioorg Med Chem 23: 7394-404 (2015)
- Grimster, NP; Anderson, E; Alimzhanov, M; Bebernitz, G; Bell, K; Chuaqui, C; Deegan, T; Ferguson, AD; Gero, T; Harsch, A; Huszar, D; Kawatkar, A; Kettle, JG; Lyne, P; Read, JA; Rivard Costa, C; Ruston, L; Schroeder, P; Shi, J; Su, Q; Throner, S; Toader, D; Vasbinder, M; Woessner, R; Wang, H; Wu, A; Ye, M; Zheng, W; Zinda, M J Med Chem 61: 5235-5244 (2018)
- Allan, M; Manku, S; Therrien, E; Nguyen, N; Styhler, S; Robert, MF; Goulet, AC; Petschner, AJ; Rahil, G; Robert Macleod, A; Déziel, R; Besterman, JM; Nguyen, H; Wahhab, A Bioorg Med Chem Lett 19: 1218-23 (2009)
- Bertini, S; Parkkari, T; Savinainen, JR; Arena, C; Saccomanni, G; Saguto, S; Ligresti, A; Allarŕ, M; Bruno, A; Marinelli, L; Di Marzo, V; Novellino, E; Manera, C; Macchia, M Eur J Med Chem 90: 526-36 (2015)
- Albujuq, NR; Meana, JJ; Diez-Alarcia, R; Muneta-Arrate, I; Naqvi, A; Althumayri, K; Alsehli, M J Med Chem 66: 9057-9075 (2023)
- Giannotti, D; Perrotta, E; Di Bugno, C; Nannicini, R; Harmat, NJ; Giolitti, A; Patacchini, R; Renzetti, AR; Rotondaro, L; Giuliani, S; Altamura, M; Maggi, CA J Med Chem 43: 4041-4 (2000)
- Mahalingam, AK; Wan, Y; Murugaiah, AM; Wallinder, C; Wu, X; Plouffe, B; Botros, M; Nyberg, F; Hallberg, A; Gallo-Payet, N; Alterman, M Bioorg Med Chem 18: 4570-90 (2010)
- Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Eur J Med Chem 64: 488-97 (2013)
- Iio, K; Saitoh, T; Ohshita, R; Hino, T; Amezawa, M; Takayama, Y; Nagumo, Y; Yamamoto, N; Kutsumura, N; Irukayama-Tomobe, Y; Ishikawa, Y; Tanimura, R; Yanagisawa, M; Nagase, H Bioorg Med Chem Lett 60: (2022)
- Hansen, JD; Correa, M; Alexander, M; Nagy, M; Huang, D; Sapienza, J; Lu, G; LeBrun, LA; Cathers, BE; Zhang, W; Tang, Y; Ammirante, M; Narla, RK; Piccotti, JR; Pourdehnad, M; Lopez-Girona, A J Med Chem 64: 1835-1843 (2021)
- Rahm, F; Viklund, J; Trésaugues, L; Ellermann, M; Giese, A; Ericsson, U; Forsblom, R; Ginman, T; Günther, J; Hallberg, K; Lindström, J; Persson, LB; Silvander, C; Talagas, A; Díaz-Sáez, L; Fedorov, O; Huber, KVM; Panagakou, I; Siejka, P; Gorjánácz, M; Bauser, M; Andersson, M J Med Chem 61: 2533-2551 (2018)
- Nepovimova, E; Korabecny, J; Dolezal, R; Babkova, K; Ondrejicek, A; Jun, D; Sepsova, V; Horova, A; Hrabinova, M; Soukup, O; Bukum, N; Jost, P; Muckova, L; Kassa, J; Malinak, D; Andrs, M; Kuca, K J Med Chem 58: 8985-9003 (2015)
- Salimbeni, A; Paleari, F; Canevotti, R; Criscuoli, M; Criscuoli, M; Lippi, A; Angiolini, M; Belvisi, L; Scolastico, C; Colombo, L Bioorg Med Chem Lett 7: 2205-2210 (1997)
- Mollica, L; Theret, I; Antoine, M; Perron-Sierra, F; Charton, Y; Fourquez, JM; Wierzbicki, M; Boutin, JA; Ferry, G; Decherchi, S; Bottegoni, G; Ducrot, P; Cavalli, A J Med Chem 59: 7167-76 (2016)
- Cappelli, A; Manini, M; Paolino, M; Gallelli, A; Anzini, M; Mennuni, L; Del Cadia, M; De Rienzo, F; Menziani, MC; Vomero, S ACS Med Chem Lett 2: 571-576 (2011)
- Miyazaki, M; Naito, H; Sugimoto, Y; Kawato, H; Okayama, T; Shimizu, H; Miyazaki, M; Kitagawa, M; Seki, T; Fukutake, S; Aonuma, M; Soga, T Bioorg Med Chem Lett 23: 728-32 (2013)
- Yonezawa, S; Fujiwara, K; Yamamoto, T; Hattori, K; Yamakawa, H; Muto, C; Hosono, M; Tanaka, Y; Nakano, T; Takemoto, H; Arisawa, M; Shuto, S Bioorg Med Chem 21: 6506-22 (2013)
- Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Eur J Med Chem 64: 488-97 (2013)
- Liessi, N; Cichero, E; Pesce, E; Arkel, M; Salis, A; Tomati, V; Paccagnella, M; Damonte, G; Tasso, B; Galietta, LJV; Pedemonte, N; Fossa, P; Millo, E Eur J Med Chem 144: 179-200 (2018)
- Huryn, DM; Wipf, P; LaPorte, MG; Colombo, R; Kovaliov, M; Lim, C; Alverez, CN; Yue, Z; Samankumara, LP; Chatterley, AJ; Yan, Y; Liang, M; Green, NJ; Baldwin, ET; Moore, WJ; Arkin, M; Neitz, RJ; Ang, K; Bryant, C; Bulfer, S US Patent US11247985 (2022)
- Fidan, I; Salmas, RE; Arslan, M; Sentürk, M; Durdagi, S; Ekinci, D; Sentürk, E; Cosgun, S; Supuran, CT Bioorg Med Chem 23: 7353-8 (2015)
- Asada, M; Obitsu, T; Kinoshita, A; Nagase, T; Yoshida, T; Yamaura, Y; Takizawa, H; Yoshikawa, K; Sato, K; Narita, M; Nakai, H; Toda, M; Tobe, Y Bioorg Med Chem 18: 3212-23 (2010)
- Montanari, R; Saccoccia, F; Scotti, E; Crestani, M; Godio, C; Gilardi, F; Loiodice, F; Fracchiolla, G; Laghezza, A; Tortorella, P; Lavecchia, A; Novellino, E; Mazza, F; Aschi, M; Pochetti, G J Med Chem 51: 7768-76 (2008)
- Di Maro, S; Di Leva, FS; Trotta, AM; Brancaccio, D; Portella, L; Aurilio, M; Tomassi, S; Messere, A; Sementa, D; Lastoria, S; Carotenuto, A; Novellino, E; Scala, S; Marinelli, L J Med Chem 60: 9641-9652 (2017)
- Velcicky, J; Mathison, CJN; Nikulin, V; Pflieger, D; Epple, R; Azimioara, M; Cow, C; Michellys, PY; Rigollier, P; Beisner, DR; Bodendorf, U; Guerini, D; Liu, B; Wen, B; Zaharevitz, S; Brandl, T ACS Med Chem Lett 10: 887-892 (2019)
- Babler, M; Gerritsen, ME US Patent US9572811 (2017)
- Banerjee, A; Narayana, L; Raje, FA; Pisal, DV; Kadam, PA; Gullapalli, S; Kumar, H; More, SV; Bajpai, M; Sangana, RR; Jadhav, S; Gudi, GS; Khairatkar-Joshi, N; Merugu, RR; Voleti, SR; Gharat, LA Bioorg Med Chem Lett 23: 6747-54 (2013)
- Bansal, S; Bala, M; Suthar, SK; Choudhary, S; Bhattacharya, S; Bhardwaj, V; Singla, S; Joseph, A Eur J Med Chem 80: 167-74 (2014)
- Serrán-Aguilera, L; Mariotto, E; Rubbini, G; Castro Navas, FF; Marco, C; Carrasco-Jiménez, MP; Ballarotto, M; Macchiarulo, A; Hurtado-Guerrero, R; Viola, G; Lopez-Cara, LC Eur J Med Chem 207: (2020)
- Czudor, Z; Balogh, M; Bánhegyi, P; Boros, S; Breza, N; Dobos, J; Fábián, M; Horváth, Z; Illyés, E; Markó, P; Sipos, A; Szántai-Kis, C; Szokol, B; ?rfi, L Bioorg Med Chem Lett 28: 769-773 (2018)
- Doe, C; Bentley, R; Behm, DJ; Lafferty, R; Stavenger, R; Jung, D; Bamford, M; Panchal, T; Grygielko, E; Wright, LL; Smith, GK; Chen, Z; Webb, C; Khandekar, S; Yi, T; Kirkpatrick, R; Dul, E; Jolivette, L; Marino, JP; Willette, R; Lee, D; Hu, E J Pharmacol Exp Ther 320: 89-98 (2006)
- Banerjee, M; Middya, S; Shrivastava, R; Raina, S; Surya, A; Yadav, DB; Yadav, VK; Kapoor, KK; Venkatesan, A; Smith, RA; Thompson, SK US Patent US10294212 (2019)
- van der Stelt, M; van Kuik, JA; Bari, M; van Zadelhoff, G; Leeflang, BR; Veldink, GA; Finazzi-Agrò, A; Vliegenthart, JF; Maccarrone, M J Med Chem 45: 3709-20 (2002)
- Carosati, E; Mannhold, R; Wahl, P; Hansen, JB; Fremming, T; Zamora, I; Cianchetta, G; Baroni, M J Med Chem 50: 2117-26 (2007)
- D'Agostino, LA; Sjin, RT; Niu, D; McDonald, JJ; Zhu, Z; Liu, H; Mazdiyasni, H; Petter, RC; Singh, J; Barrague, M; Gross, A; Munson, M US Patent US9695132 (2017)
- Hille, UE; Hu, Q; Vock, C; Negri, M; Bartels, M; Müller-Vieira, U; Lauterbach, T; Hartmann, RW Eur J Med Chem 44: 2765-75 (2009)
- Camps, P; Formosa, X; Galdeano, C; Gómez, T; Muñoz-Torrero, D; Scarpellini, M; Viayna, E; Badia, A; Clos, MV; Camins, A; Pallàs, M; Bartolini, M; Mancini, F; Andrisano, V; Estelrich, J; Lizondo, M; Bidon-Chanal, A; Luque, FJ J Med Chem 51: 3588-98 (2008)
- De Simone, A; Bartolini, M; Baschieri, A; Apperley, KYP; Chen, HH; Guardigni, M; Montanari, S; Kobrlova, T; Soukup, O; Valgimigli, L; Andrisano, V; Keillor, JW; Basso, M; Milelli, A Eur J Med Chem 139: 378-389 (2017)
- Nar, H; Bauer, M; Schmid, A; Stassen, JM; Wienen, W; Priepke, HW; Kauffmann, IK; Ries, UJ; Hauel, NH Structure 9: 29-37 (2001)
- Rahm, F; Viklund, J; Trésaugues, L; Ellermann, M; Giese, A; Ericsson, U; Forsblom, R; Ginman, T; Günther, J; Hallberg, K; Lindström, J; Persson, LB; Silvander, C; Talagas, A; Díaz-Sáez, L; Fedorov, O; Huber, KVM; Panagakou, I; Siejka, P; Gorjánácz, M; Bauser, M; Andersson, M J Med Chem 61: 2533-2551 (2018)
- Grob, NM; Häussinger, D; Deupi, X; Schibli, R; Behe, M; Mindt, TL J Med Chem 63: 4484-4495 (2020)
- Stefanowicz, J; S?owi?ski, T; Wróbel, MZ; Herold, F; Gomó?ka, AE; Weso?owska, A; Jastrz?bska-Wi?sek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; ?uszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; ?o?nierek, M; B?czek, T; Ulenberg, S; Belka, M; Tur?o, J Bioorg Med Chem 24: 3994-4007 (2016)
- Gallant, M; Belley, M; Carrière, MC; Chateauneuf, A; Denis, D; Lachance, N; Lamontagne, S; Metters, KM; Sawyer, N; Slipetz, D; Truchon, JF; Labelle, M Bioorg Med Chem Lett 13: 3813-6 (2003)
- Blake, JF; Burkard, M; Chan, J; Chen, H; Chou, KJ; Diaz, D; Dudley, DA; Gaudino, JJ; Gould, SE; Grina, J; Hunsaker, T; Liu, L; Martinson, M; Moreno, D; Mueller, L; Orr, C; Pacheco, P; Qin, A; Rasor, K; Ren, L; Robarge, K; Shahidi-Latham, S; Stults, J; Sullivan, F; Wang, W; Yin, J; Zhou, A; Belvin, M; Merchant, M; Moffat, J; Schwarz, JB J Med Chem 59: 5650-60 (2016)
- Swahn, BM; Sandell, J; Pyring, D; Bergh, M; Jeppsson, F; Juréus, A; Neelissen, J; Johnström, P; Schou, M; Svensson, S Bioorg Med Chem Lett 22: 4332-7 (2012)
- Zeng, Q; Rosenblum, SB; Yang, Z; Jiang, Y; McCormick, KD; Aslanian, RG; Duguma, L; Kozlowski, JA; Shih, NY; Hey, JA; West, RE; Korfmacher, WA; Berlin, M; Boyce, CW Bioorg Med Chem Lett 23: 6001-3 (2013)
- Schaller, D; Hagenow, S; Alpert, G; Naß, A; Schulz, R; Bermudez, M; Stark, H; Wolber, G ACS Med Chem Lett 8: 648-653 (2017)
- Saupe, SM; Leubner, S; Betz, M; Klebe, G; Steinmetzer, T J Med Chem 56: 820-31 (2013)
- Skerlj, R; Bridger, G; Zhou, Y; Bourque, E; McEachern, E; Langille, J; Harwig, C; Veale, D; Yang, W; Li, T; Zhu, Y; Bey, M; Baird, I; Sartori, M; Metz, M; Mosi, R; Nelson, K; Bodart, V; Wong, R; Fricker, S; Mac Farland, R; Huskens, D; Schols, D Bioorg Med Chem Lett 21: 6950-4 (2011)
- Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y J Med Chem 51: 5650-62 (2008)
- Hen, N; Bialer, M; Yagen, B; Maresca, A; Aggarwal, M; Robbins, AH; McKenna, R; Scozzafava, A; Supuran, CT J Med Chem 54: 3977-81 (2011)
- Battilocchio, C; Poce, G; Alfonso, S; Porretta, GC; Consalvi, S; Sautebin, L; Pace, S; Rossi, A; Ghelardini, C; Di Cesare Mannelli, L; Schenone, S; Giordani, A; Di Francesco, L; Patrignani, P; Biava, M Bioorg Med Chem 21: 3695-701 (2013)
- Mahy, W; Willis, NJ; Zhao, Y; Woodward, HL; Svensson, F; Sipthorp, J; Vecchia, L; Ruza, RR; Hillier, J; Kjćr, S; Frew, S; Monaghan, A; Bictash, M; Salinas, PC; Whiting, P; Vincent, JP; Jones, EY; Fish, PV J Med Chem 63: 12942-12956 (2020)
- Rossi, C; Porcelloni, M; D'Andrea, P; Fincham, CI; Ettorre, A; Mauro, S; Squarcia, A; Bigioni, M; Parlani, M; Nardelli, F; Binaschi, M; Maggi, CA; Fattori, D Bioorg Med Chem Lett 21: 2305-8 (2011)
- Axford, LC; Agarwal, PK; Anderson, KH; Andrau, LN; Atherall, J; Barker, S; Bennett, JM; Blair, M; Collins, I; Czaplewski, LG; Davies, DT; Gannon, CT; Kumar, D; Lancett, P; Logan, A; Lunniss, CJ; Mitchell, DR; Offermann, DA; Palmer, JT; Palmer, N; Pitt, GR; Pommier, S; Price, D; Narasinga Rao, B; Saxena, R; Shukla, T; Singh, AK; Singh, M; Srivastava, A; Steele, C; Stokes, NR; Thomaides-Brears, HB; Tyndall, EM; Watson, D; Haydon, DJ Bioorg Med Chem Lett 23: 6598-603 (2013)
- Arora, J; Bordeleau, M; Dube, L; Jarvie, K; Mazzocco, L; Peragine, J; Tehim, A; Egle, I Bioorg Med Chem Lett 15: 5253-6 (2005)
- Marzaro, G; Guiotto, A; Borgatti, M; Finotti, A; Gambari, R; Breveglieri, G; Chilin, A J Med Chem 56: 1830-42 (2013)
- Rosenström, U; Sköld, C; Plouffe, B; Beaudry, H; Lindeberg, G; Botros, M; Nyberg, F; Wolf, G; Karlén, A; Gallo-Payet, N; Hallberg, A J Med Chem 48: 4009-24 (2005)
- Tintori, C; Fallacara, AL; Radi, M; Zamperini, C; Dreassi, E; Crespan, E; Maga, G; Schenone, S; Musumeci, F; Brullo, C; Richters, A; Gasparrini, F; Angelucci, A; Festuccia, C; Delle Monache, S; Rauh, D; Botta, M J Med Chem 58: 347-61 (2015)
- Doll, F; Dolci, L; Valette, H; Hinnen, F; Vaufrey, F; Guenther, I; Fuseau, C; Coulon, C; Bottlaender, M; Crouzel, C J Med Chem 42: 2251-9 (1999)
- Bouaboula, M; Brollo, M; Certal, V; El-Ahmad, Y; Filoche-Romme, B; Halley, F; McCort, G; Schio, L; Tabart, M; Terrier, C; Thompson, F US Patent US9714221 (2017)
- Giraud, F; Bourhis, M; Ebrahimi, E; Herfindal, L; Choudhury, RR; Bjřrnstad, R; Dřskeland, SO; Anizon, F; Moreau, P Bioorg Med Chem 23: 7313-23 (2015)
- Knoepfel, T; Nimsgern, P; Jacquier, S; Bourrel, M; Vangrevelinghe, E; Glatthar, R; Behnke, D; Alper, PB; Michellys, PY; Deane, J; Junt, T; Zipfel, G; Limonta, S; Hawtin, S; Andre, C; Boulay, T; Loetscher, P; Faller, M; Blank, J; Feifel, R; Betschart, C J Med Chem 63: 8276-8295 (2020)
- Siu, T; Kozina, ES; Jung, J; Rosenstein, C; Mathur, A; Altman, MD; Chan, G; Xu, L; Bachman, E; Mo, JR; Bouthillette, M; Rush, T; Dinsmore, CJ; Marshall, CG; Young, JR Bioorg Med Chem Lett 20: 7421-5 (2010)
- Corręa, MF; Balico-Silva, AL; Kiss, DJ; Fernandes, GAB; Maraschin, JC; Parreiras-E-Silva, LT; Varela, MT; Simőes, SC; Bouvier, M; Keser?, GM; Costa-Neto, CM; Fernandes, JPS Bioorg Med Chem 30: (2021)
- Bozdag, M; Alafeefy, AM; Altamimi, AM; Carta, F; Supuran, CT; Vullo, D Bioorg Med Chem 25: 2782-2788 (2017)
- Baxter, EW; Conway, KA; Kennis, L; Bischoff, F; Mercken, MH; Winter, HL; Reynolds, CH; Tounge, BA; Luo, C; Scott, MK; Huang, Y; Braeken, M; Pieters, SM; Berthelot, DJ; Masure, S; Bruinzeel, WD; Jordan, AD; Parker, MH; Boyd, RE; Qu, J; Alexander, RS; Brenneman, DE; Reitz, AB J Med Chem 50: 4261-4 (2007)
- Thalji, RK; McAtee, JJ; Belyanskaya, S; Brandt, M; Brown, GD; Costell, MH; Ding, Y; Dodson, JW; Eisennagel, SH; Fries, RE; Gross, JW; Harpel, MR; Holt, DA; Israel, DI; Jolivette, LJ; Krosky, D; Li, H; Lu, Q; Mandichak, T; Roethke, T; Schnackenberg, CG; Schwartz, B; Shewchuk, LM; Xie, W; Behm, DJ; Douglas, SA; Shaw, AL; Marino, JP Bioorg Med Chem Lett 23: 3584-8 (2013)
- Butini, S; Brindisi, M; Cosconati, S; Marinelli, L; Borrelli, G; Coccone, SS; Ramunno, A; Campiani, G; Novellino, E; Zanoli, S; Samuele, A; Giorgi, G; Bergamini, A; Mattia, MD; Lalli, S; Galletti, B; Gemma, S; Maga, G J Med Chem 52: 1224-8 (2009)
- Vaz, RJ; Gao, Z; Pribish, J; Chen, X; Levell, J; Davis, L; Albert, E; Brollo, M; Ugolini, A; Cramer, DM; Cairns, J; Sides, K; Liu, F; Kwong, J; Kang, J; Rebello, S; Elliot, M; Lim, H; Chellaraj, V; Singleton, RW; Li, Y Bioorg Med Chem Lett 14: 6053-6 (2004)
- Bruncko, M; Tahir, SK; Song, X; Chen, J; Ding, H; Huth, JR; Jin, S; Judge, RA; Madar, DJ; Park, CH; Park, CM; Petros, AM; Tse, C; Rosenberg, SH; Elmore, SW Bioorg Med Chem Lett 20: 7503-6 (2010)
- Yeh, VS; Patel, JR; Yong, H; Kurukulasuriya, R; Fung, S; Monzon, K; Chiou, W; Wang, J; Stolarik, D; Imade, H; Beno, D; Brune, M; Jacobson, P; Sham, H; Link, JT Bioorg Med Chem Lett 16: 5414-9 (2006)
- Spicer, JA; Lena, G; Lyons, DM; Huttunen, KM; Miller, CK; O'Connor, PD; Bull, M; Helsby, N; Jamieson, SM; Denny, WA; Ciccone, A; Browne, KA; Lopez, JA; Rudd-Schmidt, J; Voskoboinik, I; Trapani, JA J Med Chem 56: 9542-55 (2014)
- Urbani, P; Cavallo, P; Cascio, MG; Buonerba, M; De Martino, G; Di Marzo, V; Saturnino, C Bioorg Med Chem Lett 16: 138-41 (2005)
- Kinzel, O; Steeneck, C; Schlüter, T; Schulz, A; Gege, C; Hahn, U; Hambruch, E; Hornberger, M; Spalwisz, A; Frick, K; Perovic-Ottstadt, S; Deuschle, U; Burnet, M; Kremoser, C Bioorg Med Chem Lett 26: 3746-53 (2016)
- Mallinger, A; Schiemann, K; Rink, C; Stieber, F; Calderini, M; Crumpler, S; Stubbs, M; Adeniji-Popoola, O; Poeschke, O; Busch, M; Czodrowski, P; Musil, D; Schwarz, D; Ortiz-Ruiz, MJ; Schneider, R; Thai, C; Valenti, M; de Haven Brandon, A; Burke, R; Workman, P; Dale, T; Wienke, D; Clarke, PA; Esdar, C; Raynaud, FI; Eccles, SA; Rohdich, F; Blagg, J J Med Chem 59: 1078-101 (2016)
- Malwal, SR; Mazurek, B; Ko, J; Xie, P; Barnes, C; Varvitsiotis, C; Zimmerman, MD; Olatunji, S; Lee, J; Xie, M; Sarathy, J; Caffrey, M; Strynadka, NCJ; Dartois, V; Dick, T; Lee, BNR; Russell, DG; Oldfield, E J Med Chem 66: 7553-7569 (2023)
- Zhou, Y; Mowlazadeh Haghighi, S; Sawyer, JR; Hruby, VJ; Cai, M J Med Chem 66: 6715-6724 (2023)
- Vanotti, E; Caldarelli, M; Cirla, A; Forte, B; Ermoli, A; Menichincheri, M; Pillan, A; Scolaro, A US Patent US9670191 (2017)
- Wucherer-Plietker, M; Merkul, E; Müller, TJ; Esdar, C; Knöchel, T; Heinrich, T; Buchstaller, HP; Greiner, H; Dorsch, D; Finsinger, D; Calderini, M; Bruge, D; Grädler, U Bioorg Med Chem Lett 26: 3073-80 (2016)
- Caligiuri, M; Molz, L; Liu, Q; Kaplan, F; Xu, JP; Majeti, JZ; Ramos-Kelsey, R; Murthi, K; Lievens, S; Tavernier, J; Kley, N Chem Biol 13: 711-22 (2006)
- Porter, J; Lumb, S; Franklin, RJ; Gascon-Simorte, JM; Calmiano, M; Riche, KL; Lallemand, B; Keyaerts, J; Edwards, H; Maloney, A; Delgado, J; King, L; Foley, A; Lecomte, F; Reuberson, J; Meier, C; Batchelor, M Bioorg Med Chem Lett 19: 2780-4 (2009)
- Zhang, H; Ding, CZ; Lai, Z; Chen, SS; Devasthale, P; Herpin, T; Morton, G; Qu, F; Ryono, D; Smirk, R; Wang, W; Wu, S; Ye, XX; Li, YX; Apedo, A; Farrelly, D; Wang, T; Gu, L; Morgan, N; Flynn, N; Chu, C; Kunselman, L; Lippy, J; Locke, K; O'Malley, K; Harrity, T; Cap, M; Zhang, L; Hosagrahara, V; Kadiyala, P; Xu, C; Doweyko, AM; Zahler, R; Hariharan, N; Cheng, PT Bioorg Med Chem Lett 25: 1196-205 (2015)
- Costantino, L; Rastelli, G; Vescovini, K; Cignarella, G; Vianello, P; Del Corso, A; Cappiello, M; Mura, U; Barlocco, D J Med Chem 39: 4396-405 (1996)
- Sechi, M; Innocenti, A; Pala, N; Rogolino, D; Carcelli, M; Scozzafava, A; Supuran, CT Bioorg Med Chem Lett 22: 5801-6 (2012)
- Castillo, M; Forns, P; Erra, M; Mir, M; López, M; Maldonado, M; Orellana, A; Carreño, C; Ramis, I; Miralpeix, M; Vidal, B Bioorg Med Chem Lett 22: 5419-23 (2012)
- Pisani, L; Catto, M; Nicolotti, O; Grossi, G; Di Braccio, M; Soto-Otero, R; Mendez-Alvarez, E; Stefanachi, A; Gadaleta, D; Carotti, A Eur J Med Chem 70: 723-39 (2013)
- Nocentini, A; Ceruso, M; Bua, S; Lomelino, CL; Andring, JT; McKenna, R; Lanzi, C; Sgambellone, S; Pecori, R; Matucci, R; Filippi, L; Gratteri, P; Carta, F; Masini, E; Selleri, S; Supuran, CT J Med Chem 61: 5380-5394 (2018)
- Jacobson, KA; Ohno, M; Duong, HT; Kim, SK; Tchilibon, S; Cesnek, M; Holý, A; Gao, ZG Chem Biol 12: 237-47 (2005)
- Mahasenan, KV; Ding, D; Gao, M; Nguyen, TT; Suckow, MA; Schroeder, VA; Wolter, WR; Chang, M; Mobashery, S ACS Med Chem Lett 9: 708-713 (2018)
- Rewcastle, GW; Gamage, SA; Flanagan, JU; Kendall, JD; Denny, WA; Baguley, BC; Buchanan, CM; Chao, M; Kestell, P; Kolekar, S; Lee, WJ; Lill, CL; Malik, A; Singh, R; Jamieson, SM; Shepherd, PR Eur J Med Chem 64: 137-47 (2013)
- Liedtke, AJ; Adeniji, AO; Chen, M; Byrns, MC; Jin, Y; Christianson, DW; Marnett, LJ; Penning, TM J Med Chem 56: 2429-46 (2013)
- Sun, Y; Xue, Y; Liu, H; Mu, S; Sun, P; Sun, Y; Wang, L; Wang, H; Wang, J; Wu, T; Yin, W; Qin, Q; Sun, Y; Yang, H; Zhao, D; Cheng, M J Med Chem 66: 2396-2421 (2023)
- Matthews, TP; McHardy, T; Klair, S; Boxall, K; Fisher, M; Cherry, M; Allen, CE; Addison, GJ; Ellard, J; Aherne, GW; Westwood, IM; van Montfort, R; Garrett, MD; Reader, JC; Collins, I Bioorg Med Chem Lett 20: 4045-9 (2010)
- Cheung, M; Tangirala, RS US Patent US9796729 (2017)
- Rueeger, H; Rigollier, P; Yamaguchi, Y; Schmidlin, T; Schilling, W; Criscione, L; Whitebread, S; Chiesi, M; Walker, MW; Dhanoa, D; Islam, I; Zhang, J; Gluchowski, C Bioorg Med Chem Lett 10: 1175-9 (2000)
- Seabrook, GR; Sutton, KG; Jarolimek, W; Hollingworth, GJ; Teague, S; Webb, J; Clark, N; Boyce, S; Kerby, J; Ali, Z; Chou, M; Middleton, R; Kaczorowski, G; Jones, AB J Pharmacol Exp Ther 303: 1052-60 (2002)
- Chu, M; Mierzwa, R; He, L; King, A; Patel, M; Pichardo, J; Hart, A; Butkiewicz, N; Puar, MS Bioorg Med Chem Lett 9: 1949-52 (1999)
- Flavin, MT; Rizzo, JD; Khilevich, A; Kucherenko, A; Sheinkman, AK; Vilaychack, V; Lin, L; Chen, W; Greenwood, EM; Pengsuparp, T; Pezzuto, JM; Hughes, SH; Flavin, TM; Cibulski, M; Boulanger, WA; Shone, RL; Xu, ZQ J Med Chem 39: 1303-13 (1996)
- Kaller, MR; Harried, SS; Albrecht, B; Amarante, P; Babu-Khan, S; Bartberger, MD; Brown, J; Brown, R; Chen, K; Cheng, Y; Citron, M; Croghan, MD; Graceffa, R; Hickman, D; Judd, T; Kriemen, C; La, D; Li, V; Lopez, P; Luo, Y; Masse, C; Monenschein, H; Nguyen, T; Pennington, LD; Miguel, TS; Sickmier, EA; Wahl, RC; Weiss, MM; Wen, PH; Williamson, T; Wood, S; Xue, M; Yang, B; Zhang, J; Patel, V; Zhong, W; Hitchcock, S ACS Med Chem Lett 3: 886-891 (2012)
- Armani, E; Amari, G; Rizzi, A; De Fanti, R; Ghidini, E; Capaldi, C; Carzaniga, L; Caruso, P; Guala, M; Peretto, I; La Porta, E; Bolzoni, PT; Facchinetti, F; Carnini, C; Moretto, N; Patacchini, R; Bassani, F; Cenacchi, V; Volta, R; Amadei, F; Capacchi, S; Delcanale, M; Puccini, P; Catinella, S; Civelli, M; Villetti, G J Med Chem 57: 793-816 (2014)
- Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H Bioorg Med Chem Lett 7: 2223-2228 (1997)
- McCoull, W; Boyd, S; Brown, MR; Coen, M; Collingwood, O; Davies, NL; Doherty, A; Fairley, G; Goldberg, K; Hardaker, E; He, G; Hennessy, EJ; Hopcroft, P; Hodgson, G; Jackson, A; Jiang, X; Karmokar, A; Lainé, AL; Lindsay, N; Mao, Y; Markandu, R; McMurray, L; McLean, N; Mooney, L; Musgrove, H; Nissink, JWM; Pflug, A; Reddy, VP; Rawlins, PB; Rivers, E; Schimpl, M; Smith, GF; Tentarelli, S; Travers, J; Troup, RI; Walton, J; Wang, C; Wilkinson, S; Williamson, B; Winter-Holt, J; Yang, D; Zheng, Y; Zhu, Q; Smith, PD J Med Chem 64: 13524-13539 (2021)
- Stahlecker, J; Klett, T; Schwer, M; Jaag, S; Dammann, M; Ernst, LN; Braun, MB; Zimmermann, MO; Kramer, M; Lämmerhofer, M; Stehle, T; Coles, M; Boeckler, FM RSC Med Chem 13: 1575-1586 (2022)
- Collin, M; Brohm, D; Héroult, M; Lobell, M; Hübsch, W; Lustig, K; Grünewald, S; Bömer, U; Vöhringer, V; Lindner, N US Patent US9598416 (2017)
- Wang, Y; Yu, M; Zhu, J; Zhang, JK; Kayser, F; Medina, JC; Siegler, K; Conn, M; Shan, B; Grillo, MP; Liu, JJ; Coward, P Bioorg Med Chem Lett 24: 1133-7 (2014)
- Njoroge, FG; Taveras, AG; Kelly, J; Remiszewski, S; Mallams, AK; Wolin, R; Afonso, A; Cooper, AB; Rane, DF; Liu, YT; Wong, J; Vibulbhan, B; Pinto, P; Deskus, J; Alvarez, CS; del Rosario, J; Connolly, M; Wang, J; Desai, J; Rossman, RR; Bishop, WR; Patton, R; Wang, L; Kirschmeier, P; Ganguly, AK J Med Chem 41: 4890-902 (1998)
- Leopoldo, M; Lacivita, E; De Giorgio, P; Fracasso, C; Guzzetti, S; Caccia, S; Contino, M; Colabufo, NA; Berardi, F; Perrone, R J Med Chem 51: 5813-22 (2008)
- Heightman, TD; Berdini, V; Braithwaite, H; Buck, IM; Cassidy, M; Castro, J; Courtin, A; Day, JEH; East, C; Fazal, L; Graham, B; Griffiths-Jones, CM; Lyons, JF; Martins, V; Muench, S; Munck, JM; Norton, D; O'Reilly, M; Palmer, N; Pathuri, P; Reader, M; Rees, DC; Rich, SJ; Richardson, C; Saini, H; Thompson, NT; Wallis, NG; Walton, H; Wilsher, NE; Woolford, AJ; Cooke, M; Cousin, D; Onions, S; Shannon, J; Watts, J; Murray, CW J Med Chem 61: 4978-4992 (2018)
- Andrés, JI; Alonso, JM; Díaz, A; Fernández, J; Iturrino, L; Martínez, P; Matesanz, E; Freyne, EJ; Deroose, F; Boeckx, G; Petit, D; Diels, G; Megens, A; Somers, M; Van Wauwe, J; Stoppie, P; Cools, M; De Clerck, F; Peeters, D; de Chaffoy, D Bioorg Med Chem Lett 12: 653-8 (2002)
- Verhoest, PR; Proulx-Lafrance, C; Corman, M; Chenard, L; Helal, CJ; Hou, X; Kleiman, R; Liu, S; Marr, E; Menniti, FS; Schmidt, CJ; Vanase-Frawley, M; Schmidt, AW; Williams, RD; Nelson, FR; Fonseca, KR; Liras, S J Med Chem 52: 7946-9 (2009)
- Micheli, F; Cavanni, P; Andreotti, D; Arban, R; Benedetti, R; Bertani, B; Bettati, M; Bettelini, L; Bonanomi, G; Braggio, S; Carletti, R; Checchia, A; Corsi, M; Fazzolari, E; Fontana, S; Marchioro, C; Merlo-Pich, E; Negri, M; Oliosi, B; Ratti, E; Read, KD; Roscic, M; Sartori, I; Spada, S; Tedesco, G; Tarsi, L; Terreni, S; Visentini, F; Zocchi, A; Zonzini, L; Di Fabio, R J Med Chem 53: 4989-5001 (2010)
- Varnes, JG; Gardner, DS; Santella, JB; Duncia, JV; Estrella, M; Watson, PS; Clark, CM; Ko, SS; Welch, P; Covington, M; Stowell, N; Wadman, E; Davies, P; Solomon, K; Newton, RC; Trainor, GL; Decicco, CP; Wacker, DA Bioorg Med Chem Lett 14: 1645-9 (2004)
- He, L; Zhang, MY; Cox, M; Zhang, Q; Donnell, AF; Zhang, Y; Tarby, C; Gill, P; Subbaiah, MAM; Ramar, T; Reddy, M; Puttapaka, V; Li, YX; Sivaprakasam, P; Critton, D; Mulligan, D; Xie, C; Ramakrishnan, R; Nagar, J; Dudhgaonkar, S; Murtaza, A; Oderinde, MS; Schieven, GL; Mathur, A; Gavai, AV; Vite, G; Gangwar, S; Poudel, YB ACS Med Chem Lett 15: 189-196 (2024)
- Albaugh, PA; Marshall, L; Gregory, J; White, G; Hutchison, A; Ross, PC; Gallagher, DW; Tallman, JF; Crago, M; Cassella, JV J Med Chem 45: 5043-51 (2002)
- Huang, D; Poon, SF; Chapman, DF; Chung, J; Cramer, M; Reger, TS; Roppe, JR; Tehrani, L; Cosford, ND; Smith, ND Bioorg Med Chem Lett 14: 5473-6 (2004)
- Blum, CA; Caldwell, T; Zheng, X; Bakthavatchalam, R; Capitosti, S; Brielmann, H; De Lombaert, S; Kershaw, MT; Matson, D; Krause, JE; Cortright, D; Crandall, M; Martin, WJ; Murphy, BA; Boyce, S; Jones, AB; Mason, G; Rycroft, W; Perrett, H; Conley, R; Burnaby-Davies, N; Chenard, BL; Hodgetts, KJ J Med Chem 53: 3330-48 (2010)
- Pochetti, G; Godio, C; Mitro, N; Caruso, D; Galmozzi, A; Scurati, S; Loiodice, F; Fracchiolla, G; Tortorella, P; Laghezza, A; Lavecchia, A; Novellino, E; Mazza, F; Crestani, M J Biol Chem 282: 17314-24 (2007)
- Salimbeni, A; Paleari, F; Canevotti, R; Criscuoli, M; Criscuoli, M; Lippi, A; Angiolini, M; Belvisi, L; Scolastico, C; Colombo, L Bioorg Med Chem Lett 7: 2205-2210 (1997)
- Talukdar, A; Morgunova, E; Duan, J; Meining, W; Foloppe, N; Nilsson, L; Bacher, A; Illarionov, B; Fischer, M; Ladenstein, R; Cushman, M Bioorg Med Chem 18: 3518-34 (2010)
- Klein, SI; Czekaj, M; Gardner, CJ; Guertin, KR; Cheney, DL; Spada, AP; Bolton, SA; Brown, K; Colussi, D; Heran, CL; Morgan, SR; Leadley, RJ; Dunwiddie, CT; Perrone, MH; Chu, V J Med Chem 41: 437-50 (1998)
- Menichincheri, M; Albanese, C; Alli, C; Ballinari, D; Bargiotti, A; Caldarelli, M; Ciavolella, A; Cirla, A; Colombo, M; Colotta, F; Croci, V; D'Alessio, R; D'Anello, M; Ermoli, A; Fiorentini, F; Forte, B; Galvani, A; Giordano, P; Isacchi, A; Martina, K; Molinari, A; Moll, JK; Montagnoli, A; Orsini, P; Orzi, F; Pesenti, E; Pillan, A; Roletto, F; Scolaro, A; Tatò, M; Tibolla, M; Valsasina, B; Varasi, M; Vianello, P; Volpi, D; Santocanale, C; Vanotti, E J Med Chem 53: 7296-315 (2010)
- Cioffi, G; D'Auria, M; Braca, A; Mendez, J; Castillo, A; Morelli, I; De Simone, F; De Tommasi, N J Nat Prod 65: 1526-9 (2002)
- Su, S; Clarke, A; Han, Y; Chao, HJ; Bostwick, J; Schumacher, W; Wang, T; Yan, M; Hsu, MY; Simmons, E; Luk, C; Xu, C; Dabros, M; Galella, M; Onorato, J; Gordon, D; Wexler, R; Gargalovic, PS; Lawrence, RM J Med Chem 62: 10456-10465 (2019)
- Hamilton, NM; Dawson, M; Fairweather, EE; Hamilton, NS; Hitchin, JR; James, DI; Jones, SD; Jordan, AM; Lyons, AJ; Small, HF; Thomson, GJ; Waddell, ID; Ogilvie, DJ J Med Chem 55: 4431-45 (2012)
- Hemmerling, M; Edman, K; Lepistö, M; Eriksson, A; Ivanova, S; Dahmén, J; Rehwinkel, H; Berger, M; Hendrickx, R; Dearman, M; Jensen, TJ; Wissler, L; Hansson, T Bioorg Med Chem Lett 26: 5741-5748 (2016)
- Brak, K; Kerr, ID; Barrett, KT; Fuchi, N; Debnath, M; Ang, K; Engel, JC; McKerrow, JH; Doyle, PS; Brinen, LS; Ellman, JA J Med Chem 53: 1763-73 (2010)
- Dechantsreiter, M; Grob, JE; Macsweeney, A; Miltz, W; Randl, SA; Sedrani, R; Sellner, H; Sirockin, F; Valeur, E US Patent US9452990 (2016)
- Hoefgen, B; Decker, M; Mohr, P; Schramm, AM; Rostom, SA; El-Subbagh, H; Schweikert, PM; Rudolf, DR; Kassack, MU; Lehmann, J J Med Chem 49: 760-9 (2006)
- Mejdrová, I; Chalupská, D; Placková, P; Müller, C; ?ála, M; Klíma, M; Baumlová, A; Hrebabecký, H; Procházková, E; Dejmek, M; Strunin, D; Weber, J; Lee, G; Matou?ová, M; Mertlíková-Kaiserová, H; Ziebuhr, J; Birkus, G; Boura, E; Nencka, R J Med Chem 60: 100-118 (2017)
- Armani, E; Amari, G; Rizzi, A; De Fanti, R; Ghidini, E; Capaldi, C; Carzaniga, L; Caruso, P; Guala, M; Peretto, I; La Porta, E; Bolzoni, PT; Facchinetti, F; Carnini, C; Moretto, N; Patacchini, R; Bassani, F; Cenacchi, V; Volta, R; Amadei, F; Capacchi, S; Delcanale, M; Puccini, P; Catinella, S; Civelli, M; Villetti, G J Med Chem 57: 793-816 (2014)
- Shishodia, S; Demetriades, M; Zhang, D; Tam, NY; Maheswaran, P; Clunie-O'Connor, C; Tumber, A; Leung, IKH; Ng, YM; Leissing, TM; El-Sagheer, AH; Salah, E; Brown, T; Aik, WS; McDonough, MA; Schofield, CJ J Med Chem 64: 16609-16625 (2021)
- Tian, C; Yang, C; Wu, T; Lu, M; Chen, Y; Yang, Y; Liu, X; Ling, Y; Deng, M; Jia, Y; Zhou, Y Bioorg Med Chem Lett 48: (2021)
- Poel, TJ; Thomas, RC; Adams, WJ; Aristoff, PA; Barbachyn, MR; Boyer, FE; Brieland, J; Brideau, R; Brodfuehrer, J; Brown, AP; Choy, AL; Dermyer, M; Dority, M; Ford, CW; Gadwood, RC; Hanna, D; Hongliang, C; Huband, MD; Huber, C; Kelly, R; Kim, JY; Martin, JP; Pagano, PJ; Ross, D; Skerlos, L; Sulavik, MC; Zhu, T; Zurenko, GE; Prasad, JV J Med Chem 50: 5886-9 (2007)
- Gadhachanda, VR; Wang, Q; Pais, G; Hashimoto, A; Chen, D; Wang, X; Agarwal, A; Deshpande, M; Wiles, JA; Phadke, AS US Patent US9796741 (2017)
- Desjardins, M; Desgagnes, J; Lacoste, L; Yang, F; Morin, M; Lapointe, J; Chenevert, R Bioorg Med Chem Lett 7: 2363-2366 (1997)
- Kozlova, A; Thabault, L; Dauguet, N; Deskeuvre, M; Stroobant, V; Pilotte, L; Liberelle, M; Van den Eynde, B; Frédérick, R Eur J Med Chem 227: (2022)
- Xiao, Y; Karra, S; Goutopoulos, A; Morse, NT; Zhang, S; Dhanabal, M; Tian, H; Seenisamy, J; Jayadevan, J; Caldwell, R; Potnick, J; Bleich, M; Chekler, E; Sherer, B; Sriraman, V Bioorg Med Chem Lett 29: 1660-1664 (2019)
- Toure, M; Johnson, T; Li, B; Schmidt, R; Ma, H; Neagu, C; Lopez, AU; Wang, Y; Guler, S; Xiao, Y; Henkes, R; Ho, K; Zhang, S; Chu, CL; Gundra, UM; Porichis, F; Li, L; Maurer, CK; Fang, Z; Musil, D; DiPoto, M; Friis, E; Jones, R; Jones, C; Cummings, J; Chekler, E; Tanzer, EM; Huck, B; Sherer, B Bioorg Med Chem 92: (2023)
- Dichiara, M; Ambrosio, FA; Lee, SM; Ruiz-Cantero, MC; Lombino, J; Coricello, A; Costa, G; Shah, D; Costanzo, G; Pasquinucci, L; Son, KN; Cosentino, G; González-Cano, R; Marrazzo, A; Aakalu, VK; Cobos, EJ; Alcaro, S; Amata, E J Med Chem 66: 11447-11463 (2023)
- Colabufo, NA; Berardi, F; Perrone, R; Rapposelli, S; Digiacomo, M; Vanni, M; Balsamo, A J Med Chem 51: 1415-22 (2008)
- Singh, A; Dirain, M; Witek, R; Rocca, JR; Edison, AS; Haskell-Luevano, C J Med Chem 56: 2747-63 (2013)
- Sinha, S; Doble, M; Manju, SL Bioorg Med Chem 27: 3745-3759 (2019)
- Wu, WL; Burnett, DA; Domalski, M; Greenlee, WJ; Li, C; Bertorelli, R; Fredduzzi, S; Lozza, G; Veltri, A; Reggiani, A J Med Chem 50: 5550-3 (2007)
- Parcella, K; Eastman, K; Yeung, KS; Grant-Young, KA; Zhu, J; Wang, T; Zhang, Z; Yin, Z; Parker, D; Mosure, K; Fang, H; Wang, YK; Lemm, J; Zhuo, X; Hanumegowda, U; Liu, M; Rigat, K; Donoso, M; Tuttle, M; Zvyaga, T; Haarhoff, Z; Meanwell, NA; Soars, MG; Roberts, SB; Kadow, JF ACS Med Chem Lett 8: 771-774 (2017)
- Poel, TJ; Thomas, RC; Adams, WJ; Aristoff, PA; Barbachyn, MR; Boyer, FE; Brieland, J; Brideau, R; Brodfuehrer, J; Brown, AP; Choy, AL; Dermyer, M; Dority, M; Ford, CW; Gadwood, RC; Hanna, D; Hongliang, C; Huband, MD; Huber, C; Kelly, R; Kim, JY; Martin, JP; Pagano, PJ; Ross, D; Skerlos, L; Sulavik, MC; Zhu, T; Zurenko, GE; Prasad, JV J Med Chem 50: 5886-9 (2007)
- Michaelis, S; Marais, A; Schrey, AK; Graebner, OY; Schaudt, C; Sefkow, M; Kroll, F; Dreger, M; Glinski, M; Koester, H; Metternich, R; Fischer, JJ J Med Chem 55: 3934-44 (2012)
- Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Bioorg Med Chem Lett 11: 2189-92 (2001)
- Okolotowicz, KJ; Dwyer, M; Ryan, D; Cheng, J; Cashman, EA; Moore, S; Mercola, M; Cashman, JR Bioorg Med Chem 26: 4441-4451 (2018)
- Gray, NS; De Clercq, D; Jang, J; Janne, P; To, C; Eck, M; Park, E; Heppner, D US Patent US11584746 (2023)
- Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H US Patent US9597310 (2017)
- Debenham, SD; Chan, A; Lau, FW; Liu, W; Wood, HB; Lemme, K; Colwell, L; Habulihaz, B; Akiyama, TE; Einstein, M; Doebber, TW; Sharma, N; Wang, CF; Wu, M; Berger, JP; Meinke, PT Bioorg Med Chem Lett 18: 4798-801 (2008)
- Ojima, I; Deutsch, D; Kaczocha, M; Hu, K; Tong, S; Elmes, M; Yan, S US Patent US10968163 (2021)
- Caraballo, R; Larsson, M; Nilsson, SK; Ericsson, M; Qian, W; Nguyen Tran, NP; Kindahl, T; Svensson, R; Saar, V; Artursson, P; Olivecrona, G; Enquist, PA; Elofsson, M Eur J Med Chem 103: 191-209 (2015)
- Cee, VJ; Albrecht, BK; Geuns-Meyer, S; Hughes, P; Bellon, S; Bready, J; Caenepeel, S; Chaffee, SC; Coxon, A; Emery, M; Fretland, J; Gallant, P; Gu, Y; Hodous, BL; Hoffman, D; Johnson, RE; Kendall, R; Kim, JL; Long, AM; McGowan, D; Morrison, M; Olivieri, PR; Patel, VF; Polverino, A; Powers, D; Rose, P; Wang, L; Zhao, H J Med Chem 50: 627-40 (2007)
- Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M J Med Chem 62: 1817-1836 (2019)
- Palica, K; Deufel, F; Skagseth, S; Di Santo Metzler, GP; Thoma, J; Andersson Rasmussen, A; Valkonen, A; Sunnerhagen, P; Leiros, HS; Andersson, H; Erdelyi, M RSC Med Chem 14: 2277-2300 (2023)
- Castillo, M; Forns, P; Erra, M; Mir, M; López, M; Maldonado, M; Orellana, A; Carreño, C; Ramis, I; Miralpeix, M; Vidal, B Bioorg Med Chem Lett 22: 5419-23 (2012)
- Furber, M; Alcaraz, L; Bent, JE; Beyerbach, A; Bowers, K; Braddock, M; Caffrey, MV; Cladingboel, D; Collington, J; Donald, DK; Fagura, M; Ince, F; Kinchin, EC; Laurent, C; Lawson, M; Luker, TJ; Mortimore, MM; Pimm, AD; Riley, RJ; Roberts, N; Robertson, M; Theaker, J; Thorne, PV; Weaver, R; Webborn, P; Willis, P J Med Chem 50: 5882-5 (2007)
- Manca, I; Mastinu, A; Olimpieri, F; Falzoi, M; Sani, M; Ruiu, S; Loriga, G; Volonterio, A; Tambaro, S; Bottazzi, ME; Zanda, M; Pinna, GA; Lazzari, P Eur J Med Chem 62: 256-69 (2013)
- Maccallini, C; Arias, F; Gallorini, M; Amoia, P; Ammazzalorso, A; De Filippis, B; Fantacuzzi, M; Giampietro, L; Cataldi, A; Camacho, ME; Amoroso, R ACS Med Chem Lett 11: 1470-1475 (2020)
- Fantini, M; Rivara, M; Zuliani, V; Kalmar, CL; Vacondio, F; Silva, C; Baheti, AR; Singh, N; Merrick, EC; Katari, RS; Cocconcelli, G; Ghiron, C; Patel, MK Bioorg Med Chem 17: 3642-8 (2009)
- Fardis, M; Jin, H; Jabri, S; Cai, RZ; Mish, M; Tsiang, M; Kim, CU Bioorg Med Chem Lett 16: 4031-5 (2006)
- Laufer, R; Forrest, B; Li, SW; Liu, Y; Sampson, P; Edwards, L; Lang, Y; Awrey, DE; Mao, G; Plotnikova, O; Leung, G; Hodgson, R; Beletskaya, I; Mason, JM; Luo, X; Wei, X; Yao, Y; Feher, M; Ban, F; Kiarash, R; Green, E; Mak, TW; Pan, G; Pauls, HW J Med Chem 56: 6069-87 (2013)
- Feledziak, M; Michaux, C; Urbach, A; Labar, G; Muccioli, GG; Lambert, DM; Marchand-Brynaert, J J Med Chem 52: 7054-68 (2009)
- Zhang, S; Chen, X; Wu, C; Xu, H; Xie, X; Feng, M; Hu, S; Bai, H; Gao, F; Tong, L; Ding, J; Liu, H; Xie, Z; Wang, J J Med Chem 65: 7697-7716 (2022)
- Zampieri, D; Laurini, E; Vio, L; Fermeglia, M; Pricl, S; Wünsch, B; Schepmann, D; Mamolo, MG Eur J Med Chem 90: 797-808 (2015)
- Narjes, F; Crescenzi, B; Ferrara, M; Habermann, J; Colarusso, S; Ferreira, Mdel R; Stansfield, I; Mackay, AC; Conte, I; Ercolani, C; Zaramella, S; Palumbi, MC; Meuleman, P; Leroux-Roels, G; Giuliano, C; Fiore, F; Di Marco, S; Baiocco, P; Koch, U; Migliaccio, G; Altamura, S; Laufer, R; De Francesco, R; Rowley, M J Med Chem 54: 289-301 (2011)
- Plyasova, AA; Berrino, E; Khan, II; Veselovsky, AV; Pokrovsky, VS; Angeli, A; Ferraroni, M; Supuran, CT; Pokrovskaya, MV; Alexandrova, SS; Gladilina, YA; Sokolov, NN; Hilal, A; Carta, F; Zhdanov, DD J Med Chem 64: 11432-11444 (2021)
- Haworth, KE; Harrison, T; Kulagowski, JJ; Leeson, PD; Owens, AP; Ridgill, MP; Teall, MR; Fielding, M; Chapman, K; Emms, F; Marwood, R; Patel, S; Moss, KL Bioorg Med Chem Lett 7: 2211-2216 (1997)
- Chakraborty, S; DiBerto, JF; Faouzi, A; Bernhard, SM; Gutridge, AM; Ramsey, S; Zhou, Y; Provasi, D; Nuthikattu, N; Jilakara, R; Nelson, MNF; Asher, WB; Eans, SO; Wilson, LL; Chintala, SM; Filizola, M; van Rijn, RM; Margolis, EB; Roth, BL; McLaughlin, JP; Che, T; Sames, D; Javitch, JA; Majumdar, S J Med Chem 64: 13873-13892 (2021)
- Bornot, A; Bauer, U; Brown, A; Firth, M; Hellawell, C; Engkvist, O J Med Chem 56: 1197-210 (2013)
- Zahid, H; Buchholz, CR; Singh, M; Ciccone, MF; Chan, A; Nithianantham, S; Shi, K; Aihara, H; Fischer, M; Schönbrunn, E; Dos Santos, CO; Landry, JW; Pomerantz, WCK J Med Chem 64: 13902-13917 (2021)
- Matthews, TP; McHardy, T; Klair, S; Boxall, K; Fisher, M; Cherry, M; Allen, CE; Addison, GJ; Ellard, J; Aherne, GW; Westwood, IM; van Montfort, R; Garrett, MD; Reader, JC; Collins, I Bioorg Med Chem Lett 20: 4045-9 (2010)
- Xiang, Y; Hirth, B; Asmussen, G; Biemann, HP; Bishop, KA; Good, A; Fitzgerald, M; Gladysheva, T; Jain, A; Jancsics, K; Liu, J; Metz, M; Papoulis, A; Skerlj, R; Stepp, JD; Wei, RR Bioorg Med Chem Lett 21: 3050-6 (2011)
- Fleck, M; Heine, N; Nosse, B; Roth, GJ; Heimann, A US Patent US9169205 (2015)
- Hughes, AD; Byun, D; Chen, Y; Fleury, M; Jacobsen, JR; Stangeland, EL; Wilson, RD; Yen, R US Patent US9572802 (2017)
- Pedreira, JGB; Nahidino, P; Kudolo, M; Pantsar, T; Berger, BT; Forster, M; Knapp, S; Laufer, S; Barreiro, EJ J Med Chem 63: 7347-7354 (2020)
- Merlino, F; Daniele, S; La Pietra, V; Di Maro, S; Di Leva, FS; Brancaccio, D; Tomassi, S; Giuntini, S; Cerofolini, L; Fragai, M; Luchinat, C; Reichart, F; Cavallini, C; Costa, B; Piccarducci, R; Taliani, S; Da Settimo, F; Martini, C; Kessler, H; Novellino, E; Marinelli, L J Med Chem 61: 4791-4809 (2018)
- Desage-El Murr, M; Cano, C; Golding, BT; Hardcastle, IR; Hummersome, M; Frigerio, M; Curtin, NJ; Menear, K; Richardson, C; Smith, GC; Griffin, RJ Bioorg Med Chem Lett 18: 4885-90 (2008)
- Frizler, M; Lohr, F; Furtmann, N; Kläs, J; Gütschow, M J Med Chem 54: 396-400 (2011)
- Sapkota, GP; Cummings, L; Newell, FS; Armstrong, C; Bain, J; Frodin, M; Grauert, M; Hoffmann, M; Schnapp, G; Steegmaier, M; Cohen, P; Alessi, DR Biochem J 401: 29-38 (2007)
- Salah, M; Tahoun, M; Rudzitis-Auth, J; Stotz, L; van Koppen, CJ; Laschke, MW; Abdelsamie, AS; Frotscher, M J Med Chem 66: 8975-8992 (2023)
- Li, Z; Pan, M; Su, X; Dai, Y; Fu, M; Cai, X; Shi, W; Huang, W; Qian, H Bioorg Med Chem 24: 1981-7 (2016)
- Gilbert, J; Fuentes, M; Ojasoo, T; Doré, JC; Pons, M J Med Chem 40: 1104-11 (1997)
- Kiyama, R; Honma, T; Hayashi, K; Ogawa, M; Hara, M; Fujimoto, M; Fujishita, T J Med Chem 38: 2728-41 (1995)
- Fukunaga, K; Uehara, F; Aritomo, K; Shoda, A; Hiki, S; Okuyama, M; Usui, Y; Watanabe, K; Yamakoshi, K; Kohara, T; Hanano, T; Tanaka, H; Tsuchiya, S; Sunada, S; Saito, K; Eguchi, J; Yuki, S; Asano, S; Tanaka, S; Mori, A; Yamagami, K; Baba, H; Horikawa, T; Fujimura, M Bioorg Med Chem Lett 23: 6933-7 (2013)
- Kumata, K; Yui, J; Hatori, A; Fujinaga, M; Yanamoto, K; Yamasaki, T; Kawamura, K; Wakizaka, H; Nengaki, N; Yoshida, Y; Ogawa, M; Fukumura, T; Zhang, MR J Med Chem 54: 6040-9 (2011)
- Pike, VW; Rash, KS; Chen, Z; Pedregal, C; Statnick, MA; Kimura, Y; Hong, J; Zoghbi, SS; Fujita, M; Toledo, MA; Diaz, N; Gackenheimer, SL; Tauscher, JT; Barth, VN; Innis, RB J Med Chem 54: 2687-700 (2011)
- Fukuda, M; Sasaki, T; Hashimoto, T; Miyachi, H; Waki, M; Asai, A; Takikawa, O; Ohno, O; Matsuno, K Bioorg Med Chem Lett 28: 2846-2849 (2018)
- Ueda, T; Ito, T; Tomita, K; Togame, H; Fumoto, M; Asakura, K; Oshima, T; Nishimura, S; Hanasaki, K Bioorg Med Chem Lett 20: 4631-4 (2010)
- Czudor, Z; Balogh, M; Bánhegyi, P; Boros, S; Breza, N; Dobos, J; Fábián, M; Horváth, Z; Illyés, E; Markó, P; Sipos, A; Szántai-Kis, C; Szokol, B; ?rfi, L Bioorg Med Chem Lett 28: 769-773 (2018)
- Banville, J; Rémillard, R; Ruediger, EH; Deon, DH; Gagnon, M; Dubé, L; Guy, J; Priestley, ES; Posy, SL; Maxwell, BD; Wong, PC; Lawrence, RM; Miller, MM US Patent US9688695 (2017)
- Su, S; Clarke, A; Han, Y; Chao, HJ; Bostwick, J; Schumacher, W; Wang, T; Yan, M; Hsu, MY; Simmons, E; Luk, C; Xu, C; Dabros, M; Galella, M; Onorato, J; Gordon, D; Wexler, R; Gargalovic, PS; Lawrence, RM J Med Chem 62: 10456-10465 (2019)
- Meziane-Cherif, D; Lambert, T; Dupêchez, M; Courvalin, P; Galimand, M Antimicrob Agents Chemother 52: 1264-8 (2008)
- Macdonald, D; Mastracchio, A; Perrier, H; Dubé, D; Gallant, M; Lacombe, P; Deschênes, D; Roy, B; Scheigetz, J; Bateman, K; Li, C; Trimble, LA; Day, S; Chauret, N; Nicoll-Griffith, DA; Silva, JM; Huang, Z; Laliberté, F; Liu, S; Ethier, D; Pon, D; Muise, E; Boulet, L; Chan, CC; Styhler, A; Charleson, S; Mancini, J; Masson, P; Claveau, D; Nicholson, D; Turner, M; Young, RN; Girard, Y Bioorg Med Chem Lett 15: 5241-6 (2005)
- Maccallini, C; Arias, F; Gallorini, M; Amoia, P; Ammazzalorso, A; De Filippis, B; Fantacuzzi, M; Giampietro, L; Cataldi, A; Camacho, ME; Amoroso, R ACS Med Chem Lett 11: 1470-1475 (2020)
- Mahasenan, KV; Ding, D; Gao, M; Nguyen, TT; Suckow, MA; Schroeder, VA; Wolter, WR; Chang, M; Mobashery, S ACS Med Chem Lett 9: 708-713 (2018)
- Moss, N; Beaulieu, P; Duceppe, JS; Ferland, JM; Garneau, M; Gauthier, J; Ghiro, E; Goulet, S; Guse, I; Jaramillo, J; Llinas-Brunet, M; Malenfant, E; Plante, R; Poirier, M; Soucy, F; Wernic, D; Yoakim, C; Déziel, R J Med Chem 39: 4173-80 (1996)
- Gazvoda, M; Beranic, N; Turk, S; Burja, B; Kocevar, M; Rižner, TL; Gobec, S; Polanc, S Eur J Med Chem 62: 89-97 (2013)
- ?apkauskait?, E; Zak?auskas, A; Ruibys, V; Linkuvien?, V; Paketuryt?, V; Gedgaudas, M; Kairys, V; Matulis, D Bioorg Med Chem 26: 675-687 (2018)
- Tao, Z; Barker, J; Shi, SD; Gehring, M; Sun, S Biochemistry 49: 8488-98 (2010)
- Geitmann, M; Retra, K; de Kloe, GE; Homan, E; Smit, AB; de Esch, IJ; Danielson, UH Biochemistry 49: 8143-54 (2010)
- Ding, P; Gelman, M; Kinsella, T; Singh, R; Bhamidipati, S; Velaparthi, U; Borzilleri, RM; Rahaman, H; Warrier, JS US Patent US9981944 (2018)
- Zhang, A; Ding, J; Xie, H; Song, Z; Xue, Y; Tong, L; Geng, M US Patent US10829491 (2020)
- Kalliokoski, T; Kettunen, H; Kumpulainen, E; Kettunen, E; Thieulin-Pardo, G; Neumann, L; Thomsen, M; Paul, R; Malyutina, A; Georgiadou, M Bioorg Med Chem Lett 94: (2023)
- Gerasimov, M; Marona-Lewicka, D; Kurrasch-Orbaugh, DM; Qandil, AM; Nichols, DE J Med Chem 42: 4257-63 (1999)
- Defaux, J; Antoine, M; Logé, C; Le Borgne, M; Schuster, T; Seipelt, I; Aicher, B; Teifel, M; Günther, E; Gerlach, M; Marchand, P Bioorg Med Chem Lett 24: 3748-52 (2014)
- Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Eur J Med Chem 64: 488-97 (2013)
- Li, L; Chenna, BC; Yang, KS; Cole, TR; Goodall, ZT; Giardini, M; Moghadamchargari, Z; Hernandez, EA; Gomez, J; Calvet, CM; Bernatchez, JA; Mellott, DM; Zhu, J; Rademacher, A; Thomas, D; Blankenship, LR; Drelich, A; Laganowsky, A; Tseng, CK; Liu, WR; Wand, AJ; Cruz-Reyes, J; Siqueira-Neto, JL; Meek, TD J Med Chem 64: 11267-11287 (2021)
- Burns, CJ; Harte, MF; Bu, X; Fantino, E; Giarrusso, M; Joffe, M; Kurek, M; Legge, FS; Razzino, P; Su, S; Treutlein, H; Wan, SS; Zeng, J; Wilks, AF Bioorg Med Chem Lett 19: 1206-9 (2009)
- Köse, M; Ritter, K; Thiemke, K; Gillard, M; Kostenis, E; Müller, CE ACS Med Chem Lett 5: 326-30 (2014)
- Bharathan, IT; Blackburn, C; Ciavarri, JP; Chouitar, J; Cullis, CA; D Amore, N; Fleming, PE; Gigstad, KM; Gipson, KE; Girard, M; Hu, Y; Lee, J; Li, G; Rezaei, M; Sintchak, MD; Soucy, F; Stroud, SG; Vos, TJ; Xu, H; Ye, Y US Patent US10202373 (2019)
- Cooper, AG; MacDonald, C; Glass, M; Hook, S; Tyndall, JDA; Vernall, AJ Eur J Med Chem 145: 770-789 (2018)
- Michaelis, S; Marais, A; Schrey, AK; Graebner, OY; Schaudt, C; Sefkow, M; Kroll, F; Dreger, M; Glinski, M; Koester, H; Metternich, R; Fischer, JJ J Med Chem 55: 3934-44 (2012)
- Rahm, F; Viklund, J; Trésaugues, L; Ellermann, M; Giese, A; Ericsson, U; Forsblom, R; Ginman, T; Günther, J; Hallberg, K; Lindström, J; Persson, LB; Silvander, C; Talagas, A; Díaz-Sáez, L; Fedorov, O; Huber, KVM; Panagakou, I; Siejka, P; Gorjánácz, M; Bauser, M; Andersson, M J Med Chem 61: 2533-2551 (2018)
- Schwink, L; Stengelin, S; Gossel, M; Wirth, K US Patent US8552199 (2013)
- Huynh, T; Chen, Z; Pang, S; Geng, J; Bandiera, T; Bindi, S; Vianello, P; Roletto, F; Thieffine, S; Galvani, A; Vaccaro, W; Poss, MA; Trainor, GL; Lorenzi, MV; Gottardis, M; Jayaraman, L; Purandare, AV Bioorg Med Chem Lett 19: 2924-7 (2009)
- Adonias, M; Anayaba, J; Cámara, J; Canet, E; Gateau-Olesker, A; Gero, SD; Grande, M; Hernando, JI Bioorg Med Chem Lett 3: 2547-2552 (1993)
- Anderskewitz, R; Binder, F; Grauert, M; Grundl, M; Haebel, PW; Oost, T; Pautsch, A; Peters, S; Vintonyak, V US Patent US9713606 (2017)
- Aktoudianakis, E; Cho, A; Du, Z; Graupe, M; Lad, LT; Machicao Tello, PA; Medley, JW; Metobo, SE; Mukherjee, PK; Naduthambi, D; Parkhill, EQ; Phillips, BW; Simonovich, SP; Squires, NH; Wang, P; Watkins, WJ; Xu, J; Yang, KS; Ziebenhaus, CA US Patent US10899735 (2021)
- Shao, PP; Ye, F; Chakravarty, PK; Varughese, DJ; Herrington, JB; Dai, G; Bugianesi, RM; Haedo, RJ; Swensen, AM; Warren, VA; Smith, MM; Garcia, ML; McManus, OB; Lyons, KA; Li, X; Green, M; Jochnowitz, N; McGowan, E; Mistry, S; Sun, SY; Abbadie, C; Kaczorowski, GJ; Duffy, JL J Med Chem 55: 9847-55 (2012)
- Zhou, H; Topiol, SW; Grenon, M; Jimenez, HN; Uberti, MA; Smith, DG; Brodbeck, RM; Chandrasena, G; Pedersen, H; Madsen, JC; Doller, D; Li, G Bioorg Med Chem Lett 23: 1398-406 (2013)
- Franchetti, P; Messini, L; Cappellacci, L; Grifantini, M; Lucacchini, A; Martini, C; Senatore, G J Med Chem 37: 2970-5 (1994)
- Liu, J; Li, AR; Wang, Y; Johnson, MG; Su, Y; Shen, W; Wang, X; Lively, S; Brown, M; Lai, S; Gonzalez Lopez De Turiso, F; Xu, Q; Van Lengerich, B; Schmitt, M; Fu, Z; Sun, Y; Lawlis, S; Seitz, L; Danao, J; Wait, J; Ye, Q; Tang, HL; Grillo, M; Collins, TL; Sullivan, TJ; Medina, JC ACS Med Chem Lett 2: 326-330 (2011)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Anderskewitz, R; Binder, F; Grauert, M; Grundl, M; Haebel, PW; Oost, T; Pautsch, A; Peters, S; Vintonyak, V US Patent US9713606 (2017)
- Hangeland, JJ; Friends, TJ; Doweyko, AM; Mellström, K; Sandberg, J; Grynfarb, M; Ryono, DE Bioorg Med Chem Lett 15: 4579-84 (2005)
- Redwan, IN; Dyrager, C; Solano, C; Fernández de Trocóniz, G; Voisin, L; Bliman, D; Meloche, S; Grřtli, M Eur J Med Chem 85: 127-38 (2014)
- Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A J Med Chem 54: 3109-52 (2011)
- Guerrero, M; Urbano, M; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E Bioorg Med Chem Lett 23: 614-9 (2013)
- REINER, JJ; PANTSAR, T; FLÖTGEN, D; LAUFER, S; ZENDER, L; HENNING, M US Patent US20240101538 (2024)
- Liu, J; He, S; Jian, T; Dobbelaar, PH; Sebhat, IK; Lin, LS; Goodman, A; Guo, C; Guzzo, PR; Hadden, M; Henderson, AJ; Pattamana, K; Ruenz, M; Sargent, BJ; Swenson, B; Yet, L; Tamvakopoulos, C; Peng, Q; Pan, J; Kan, Y; Palyha, O; Kelly, TM; Guan, XM; Howard, AD; Marsh, DJ; Metzger, JM; Reitman, ML; Wyvratt, MJ; Nargund, RP Bioorg Med Chem Lett 20: 2074-7 (2010)
- Yoshimoto, N; Sakamaki, Y; Haeta, M; Kato, A; Inaba, Y; Itoh, T; Nakabayashi, M; Ito, N; Yamamoto, K J Med Chem 55: 4373-81 (2012)
- Ogawa, T; Miyamae, T; Murayama, K; Okuyama, K; Okayama, T; Hagiwara, M; Sakurada, S; Morikawa, T J Med Chem 45: 5081-9 (2002)
- Hahn, M; Rogers, D J Med Chem 38: 2091-102 (1995)
- Endo, J; Hikawa, H; Hamada, M; Ishibuchi, S; Fujie, N; Sugiyama, N; Tanaka, M; Kobayashi, H; Sugahara, K; Oshita, K; Iwata, K; Ooike, S; Murata, M; Sumichika, H; Chiba, K; Adachi, K Bioorg Med Chem Lett 26: 1365-70 (2016)
- Rueda, DC; Schöffmann, A; De Mieri, M; Raith, M; Jähne, EA; Hering, S; Hamburger, M Bioorg Med Chem 22: 1276-84 (2014)
- Sisay, MT; Steinmetzer, T; Stirnberg, M; Maurer, E; Hammami, M; Bajorath, J; Gütschow, M J Med Chem 53: 5523-35 (2010)
- Hanaki, M; Murakami, K; Akagi, K; Irie, K Bioorg Med Chem 24: 304-13 (2016)
- Ashraf, A; Ejaz, SA; Rahman, SU; Siddiqui, WA; Arshad, MN; Lecka, J; Sévigny, J; Zayed, MEM; Asiri, AM; Iqbal, J; Hartinger, CG; Hanif, M Eur J Med Chem 159: 282-291 (2018)
- Kiyama, R; Honma, T; Hayashi, K; Ogawa, M; Hara, M; Fujimoto, M; Fujishita, T J Med Chem 38: 2728-41 (1995)
- Shiraishi, T; Kadono, S; Haramura, M; Kodama, H; Ono, Y; Iikura, H; Esaki, T; Koga, T; Hattori, K; Watanabe, Y; Sakamoto, A; Yoshihashi, K; Kitazawa, T; Esaki, K; Ohta, M; Sato, H; Kozono, T Bioorg Med Chem Lett 18: 4533-7 (2008)
- Ono, M; Yoshida, N; Ishibashi, K; Haratake, M; Arano, Y; Mori, H; Nakayama, M J Med Chem 48: 7253-60 (2005)
- Halim, R; Harding, M; Hufton, R; Morton, CJ; Jahangiri, S; Pool, BR; Jeynes, TP; Draffan, AG; Frey, B; Lilly, MJ US Patent US8546389 (2013)
- Wu, S; Fluxe, A; Sheffer, J; Janusz, JM; Blass, BE; White, R; Jackson, C; Hedges, R; Murawsky, M; Fang, B; Fadayel, GM; Hare, M; Djandjighian, L Bioorg Med Chem Lett 16: 6213-8 (2006)
- Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Bioorg Med Chem Lett 22: 5966-70 (2012)
- Vanjare, BD; Choi, NG; Mahajan, PG; Raza, H; Hassan, M; Han, Y; Yu, SM; Kim, SJ; Seo, SY; Lee, KH Bioorg Med Chem 41: (2021)
- Kawahata, N; Yang, MG; Luke, GP; Shakespeare, WC; Sundaramoorthi, R; Wang, Y; Johnson, D; Merry, T; Violette, S; Guan, W; Bartlett, C; Smith, J; Hatada, M; Lu, X; Dalgarno, DC; Eyermann, CJ; Bohacek, RS; Sawyer, TK Bioorg Med Chem Lett 11: 2319-23 (2001)
- Pettersson, I; Ebdrup, S; Havranek, M; Pihera, P; Korínek, M; Mogensen, JP; Jeppesen, CB; Johansson, E; Sauerberg, P Bioorg Med Chem Lett 17: 4625-9 (2007)
- Hayakawa, M; Kawaguchi, K; Kaizawa, H; Koizumi, T; Ohishi, T; Yamano, M; Okada, M; Ohta, M; Tsukamoto, S; Raynaud, FI; Parker, P; Workman, P; Waterfield, MD Bioorg Med Chem 15: 5837-44 (2007)
- Zhang, M; Jiang, L; Tao, J; Pan, Z; He, M; Su, D; He, G; Jiang, Q Bioorg Med Chem 27: 2268-2279 (2019)
- Wermuth, CG; Bourguignon, JJ; Schlewer, G; Gies, JP; Schoenfelder, A; Melikian, A; Bouchet, MJ; Chantreux, D; Molimard, JC; Heaulme, M J Med Chem 30: 239-49 (1987)
- Fensome, A; Ambler, CM; Arnold, E; Banker, ME; Brown, MF; Chrencik, J; Clark, JD; Dowty, ME; Efremov, IV; Flick, A; Gerstenberger, BS; Gopalsamy, A; Hayward, MM; Hegen, M; Hollingshead, BD; Jussif, J; Knafels, JD; Limburg, DC; Lin, D; Lin, TH; Pierce, BS; Saiah, E; Sharma, R; Symanowicz, PT; Telliez, JB; Trujillo, JI; Vajdos, FF; Vincent, F; Wan, ZK; Xing, L; Yang, X; Yang, X; Zhang, L J Med Chem 61: 8597-8612 (2018)
- Williamson, DS; Smith, GP; Mikkelsen, GK; Jensen, T; Acheson-Dossang, P; Badolo, L; Bedford, ST; Chell, V; Chen, IJ; Dokurno, P; Hentzer, M; Newland, S; Ray, SC; Shaw, T; Surgenor, AE; Terry, L; Wang, Y; Christensen, KV J Med Chem 64: 10312-10332 (2021)
- Humphries, PS; Almaden, JV; Barnum, SJ; Carlson, TJ; Do, QQ; Fraser, JD; Hess, M; Kim, YH; Ogilvie, KM; Sun, S Bioorg Med Chem Lett 16: 6116-9 (2006)
- Matyskiela, ME; Zhang, W; Man, HW; Muller, G; Khambatta, G; Baculi, F; Hickman, M; LeBrun, L; Pagarigan, B; Carmel, G; Lu, CC; Lu, G; Riley, M; Satoh, Y; Schafer, P; Daniel, TO; Carmichael, J; Cathers, BE; Chamberlain, PP J Med Chem 61: 535-542 (2017)
- Flesch, D; Ness, J; Lamers, C; Dehm, F; Popella, S; Steri, R; Ogorek, I; Hieke, M; Dannhardt, G; Werz, O; Weggen, S; Schubert-Zsilavecz, M Bioorg Med Chem Lett 25: 841-6 (2015)
- Lacivita, E; De Giorgio, P; Lee, IT; Rodeheaver, SI; Weiss, BA; Fracasso, C; Caccia, S; Berardi, F; Perrone, R; Zhang, MR; Maeda, J; Higuchi, M; Suhara, T; Schetz, JA; Leopoldo, M J Med Chem 53: 7344-55 (2010)
- Sakamoto, T; Koga, Y; Hikota, M; Matsuki, K; Murakami, M; Kikkawa, K; Fujishige, K; Kotera, J; Omori, K; Morimoto, H; Yamada, K Bioorg Med Chem Lett 24: 5175-80 (2014)
- Ma, B; Metrick, CM; Gu, C; Hoemberger, M; Bajrami, B; Bame, E; Huang, J; Mingueneau, M; Murugan, P; Santoro, JC; Tang, H; Wang, T; Hopkins, BT Bioorg Med Chem Lett 60: (2022)
- Sapkota, GP; Cummings, L; Newell, FS; Armstrong, C; Bain, J; Frodin, M; Grauert, M; Hoffmann, M; Schnapp, G; Steegmaier, M; Cohen, P; Alessi, DR Biochem J 401: 29-38 (2007)
- Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Bioorg Med Chem Lett 11: 2189-92 (2001)
- Nomura, S; Sakamaki, S; Hongu, M; Kawanishi, E; Koga, Y; Sakamoto, T; Yamamoto, Y; Ueta, K; Kimata, H; Nakayama, K; Tsuda-Tsukimoto, M J Med Chem 53: 6355-60 (2010)
- Pinkerton, AB; Sessions, EH; Hershberger, P; Maloney, PR; Peddibhotla, S; Hopf, M; Sergienko, E; Ma, CT; Smith, LH; Jackson, MR; Tanaka, J; Tsuji, T; Akiu, M; Cohen, SE; Nakamura, T; Gardell, SJ Bioorg Med Chem Lett 41: (2021)
- Giordanetto, F; Revell, JD; Knerr, L; Hostettler, M; Paunovic, A; Priest, C; Janefeldt, A; Gill, A ACS Med Chem Lett 4: 1163-8 (2013)
- Qiu, Z; Lin, X; Zhou, M; Liu, Y; Zhu, W; Chen, W; Zhang, W; Guo, L; Liu, H; Wu, G; Huang, M; Jiang, M; Xu, Z; Zhou, Z; Qin, N; Ren, S; Qiu, H; Zhong, S; Zhang, Y; Zhang, Y; Wu, X; Shi, L; Shen, F; Mao, Y; Zhou, X; Yang, W; Wu, JZ; Yang, G; Mayweg, AV; Shen, HC; Tang, G J Med Chem 59: 7651-66 (2016)
- Desage-El Murr, M; Cano, C; Golding, BT; Hardcastle, IR; Hummersome, M; Frigerio, M; Curtin, NJ; Menear, K; Richardson, C; Smith, GC; Griffin, RJ Bioorg Med Chem Lett 18: 4885-90 (2008)
- Novellino, E; Abignente, E; Cosimelli, B; Greco, G; Iadanza, M; Laneri, S; Lavecchia, A; Rimoli, MG; Settimo, FD; Primofiore, G; Tuscano, D; Trincavelli, L; Martini, C J Med Chem 45: 5030-6 (2002)
- Devillers, I; Pevet, I; Jacobelli, H; Durand, C; Fasquelle, V; Puaud, J; Gaudillière, B; Idrissi, M; Moreau, F; Wrigglesworth, R Bioorg Med Chem Lett 14: 3303-6 (2004)
- Zhang, X; Raghavan, S; Ihnat, M; Hamel, E; Zammiello, C; Bastian, A; Mooberry, SL; Gangjee, A Bioorg Med Chem 23: 2408-23 (2015)
- Kitagawa, H; Ozawa, T; Takahata, S; Iida, M Bioorg Med Chem Lett 17: 4982-6 (2007)
- Ilic, M; Ilaš, J; Dunkel, P; Mátyus, P; Bohác, A; Liekens, S; Kikelj, D Eur J Med Chem 58: 160-70 (2012)
- Kalaba, P; Aher, NY; Ili?, M; Draga?evi?, V; Wieder, M; Miklosi, AG; Zehl, M; Wackerlig, J; Roller, A; Beryozkina, T; Radoman, B; Saroja, SR; Lindner, W; Gonzalez, EP; Bakulev, V; Leban, JJ; Sitte, HH; Urban, E; Langer, T; Lubec, G J Med Chem 60: 9330-9348 (2017)
- Fujimoto, J; Okamoto, R; Noguchi, N; Hara, R; Masada, S; Kawamoto, T; Nagase, H; Tamura, YO; Imanishi, M; Takagahara, S; Kubo, K; Tohyama, K; Iida, K; Andou, T; Miyahisa, I; Matsui, J; Hayashi, R; Maekawa, T; Matsunaga, N J Med Chem 60: 8963-8981 (2017)
- Babine, RE; Bleckman, TM; Littlefield, ES; Parge, HE; Pelletier, LA; Lewis, CT; French, JV; Imbacuan, M; Katoh, S; Tatlock, JH; Showalter, RE; Villafranca, JE Bioorg Med Chem Lett 6: 385-390 (1996)
- Nagata, T; Inoue, M; Ashida, Y; Noguchi, K; Ono, M US Patent US8609710 (2013)
- Bhamidipati, S; Shaw, S; Darwish, I; Yu, J; Kolluri, R; Taylor, V; Masuda, E; Irving, M US Patent US11667643 (2023)
- Ishikawa, M; Furuuchi, T; Yamauchi, M; Yokoyama, F; Kakui, N; Sato, Y Bioorg Med Chem 18: 5441-8 (2010)
- Roaten, JB; Kazanietz, MG; Sweatman, TW; Lothstein, L; Israel, M; Parrill, AL J Med Chem 44: 1028-34 (2001)
- Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y J Med Chem 61: 7710-7728 (2018)
- Saito, S; Itoh, M; Fujisawa, T; Saito, H; Kiyotsuka, Y; Watanabe, H; Matsunaga, H; Kagoshima, Y; Suzuki, T; Ogawara, Y; Kitabayashi, K US Patent US10040791 (2018)
- Toda, N; Hao, X; Ogawa, Y; Oda, K; Yu, M; Fu, Z; Chen, Y; Kim, Y; Lizarzaburu, M; Lively, S; Lawlis, S; Murakoshi, M; Nara, F; Watanabe, N; Reagan, JD; Tian, H; Fu, A; Motani, A; Liu, Q; Lin, YJ; Zhuang, R; Xiong, Y; Fan, P; Medina, J; Li, L; Izumi, M; Okuyama, R; Shibuya, S ACS Med Chem Lett 4: 790-4 (2013)
- Lacivita, E; Leopoldo, M; Masotti, AC; Inglese, C; Berardi, F; Perrone, R; Ganguly, S; Jafurulla, M; Chattopadhyay, A J Med Chem 52: 7892-6 (2009)
- Jadav, P; Bahekar, R; Shah, SR; Patel, D; Joharapurkar, A; Jain, M; Sairam, KV; Singh, PK Bioorg Med Chem Lett 24: 1918-22 (2014)
- Cui, JJ; McTigue, M; Nambu, M; Tran-Dubé, M; Pairish, M; Shen, H; Jia, L; Cheng, H; Hoffman, J; Le, P; Jalaie, M; Goetz, GH; Ryan, K; Grodsky, N; Deng, YL; Parker, M; Timofeevski, S; Murray, BW; Yamazaki, S; Aguirre, S; Li, Q; Zou, H; Christensen, J J Med Chem 55: 8091-109 (2012)
- Zificsak, CA; Gingrich, DE; Breslin, HJ; Dunn, DD; Milkiewicz, KL; Theroff, JP; Thieu, TV; Underiner, TL; Weinberg, LR; Aimone, LD; Albom, MS; Mason, JL; Saville, L; Husten, J; Angeles, TS; Finn, JP; Jan, M; O'Kane, TM; Dobrzanski, P; Dorsey, BD Bioorg Med Chem Lett 22: 133-7 (2011)
- Conway, JG; McDonald, B; Parham, J; Keith, B; Rusnak, DW; Shaw, E; Jansen, M; Lin, P; Payne, A; Crosby, RM; Johnson, JH; Frick, L; Lin, MH; Depee, S; Tadepalli, S; Votta, B; James, I; Fuller, K; Chambers, TJ; Kull, FC; Chamberlain, SD; Hutchins, JT Proc Natl Acad Sci U S A 102: 16078-83 (2005)
- Thede, K; Flamme, I; Oehme, F; Ergüden, J; Stoll, F; Wild, H; Kolkhof, P; Beck, H; Jeske, M US Patent US8609698 (2013)
- Zhang, K; Ji, M; Lin, S; Peng, S; Zhang, Z; Zhang, M; Zhang, J; Zhang, Y; Wu, D; Tian, H; Chen, X; Xu, H J Med Chem 64: 7331-7340 (2021)
- Qiu, Z; Lin, X; Zhou, M; Liu, Y; Zhu, W; Chen, W; Zhang, W; Guo, L; Liu, H; Wu, G; Huang, M; Jiang, M; Xu, Z; Zhou, Z; Qin, N; Ren, S; Qiu, H; Zhong, S; Zhang, Y; Zhang, Y; Wu, X; Shi, L; Shen, F; Mao, Y; Zhou, X; Yang, W; Wu, JZ; Yang, G; Mayweg, AV; Shen, HC; Tang, G J Med Chem 59: 7651-66 (2016)
- Burns, CJ; Harte, MF; Bu, X; Fantino, E; Giarrusso, M; Joffe, M; Kurek, M; Legge, FS; Razzino, P; Su, S; Treutlein, H; Wan, SS; Zeng, J; Wilks, AF Bioorg Med Chem Lett 19: 1206-9 (2009)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Jovanovi?, M; Zhukovsky, D; Podolski-Reni?, A; Domra?eva, I; ?alubovskis, R; Sen?anski, M; Gli?i?, S; Sharoyko, V; Tennikova, T; Dar'in, D; Pe?i?, M; Krasavin, M Eur J Med Chem 181: (2019)
- Ojima, I; Deutsch, D; Kaczocha, M; Hu, K; Tong, S; Elmes, M; Yan, S US Patent US10968163 (2021)
- Alnabulsi, S; Santina, E; Russo, I; Hussein, B; Kadirvel, M; Chadwick, A; Bichenkova, EV; Bryce, RA; Nolan, K; Demonacos, C; Stratford, IJ; Freeman, S Eur J Med Chem 111: 33-45 (2016)
- Molette, J; Routier, J; Abla, N; Besson, D; Bombrun, A; Brun, R; Burt, H; Georgi, K; Kaiser, M; Nwaka, S; Muzerelle, M; Scheer, A ACS Med Chem Lett 4: 1037-41 (2013)
- Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y J Med Chem 55: 4336-51 (2012)
- Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y J Med Chem 55: 4336-51 (2012)
- Hidaka, K; Kimura, T; Sankaranarayanan, R; Wang, J; McDaniel, KF; Kempf, DJ; Kameoka, M; Adachi, M; Kuroki, R; Nguyen, JT; Hayashi, Y; Kiso, Y J Med Chem 61: 5138-5153 (2018)
- Yamazaki, K; Hasegawa, H; Umekawa, K; Ueki, Y; Ohashi, N; Kanaoka, M Bioorg Med Chem Lett 12: 1275-8 (2002)
- Nguyen, P; Doan, P; Rimpilainen, T; Konda Mani, S; Murugesan, A; Yli-Harja, O; Candeias, NR; Kandhavelu, M J Med Chem 64: 10908-10918 (2021)
- Kim, M; Kim, G; Kang, M; Ko, D; Nam, Y; Moon, CS; Kang, HM; Shin, JS; Werz, O; Lee, KT; Lee, JY Bioorg Med Chem Lett 41: (2021)
- Fushimi, M; Fujimori, I; Wakabayashi, T; Hasui, T; Kawakita, Y; Imamura, K; Kato, T; Murakami, M; Ishii, T; Kikko, Y; Kasahara, M; Nakatani, A; Hiura, Y; Miyamoto, M; Saikatendu, K; Zou, H; Lane, SW; Lawson, JD; Imoto, H J Med Chem 62: 4915-4935 (2019)
- Vercouillie, J; Mavel, S; Galineau, L; Ragusa, T; Innis, R; Kassiou, M; Chalon, S; Dollé, F; Besnard, JC; Guilloteau, D; Emond, P Bioorg Med Chem Lett 16: 1297-300 (2006)
- Zorbaz, T; Malinak, D; Marakovi?, N; Ma?ek Hrvat, N; Zandona, A; Novotny, M; Skarka, A; Andrys, R; Benkova, M; Soukup, O; Katalini?, M; Kuca, K; Kovarik, Z; Musilek, K J Med Chem 61: 10753-10766 (2018)
- Seko, T; Kato, M; Kohno, H; Ono, S; Hashimura, K; Takimizu, H; Nakai, K; Maegawa, H; Katsube, N; Toda, M Bioorg Med Chem Lett 11: 2067-70 (2001)
- Shirai, J; Sugiyama, H; Morimoto, S; Maezaki, H; Yamamoto, Y; Okanishi, S; Kamo, I; Matsumoto, S; Ishigami, K; Inatomi, N; Imanishi, A; Kawamoto, M; Tarui, N; Hashimoto, T; Ikeura, Y Bioorg Med Chem 20: 962-77 (2012)
- Kawai, M; Nakamura, H; Sakurada, I; Shimokawa, H; Tanaka, H; Matsumizu, M; Ando, K; Hattori, K; Ohta, A; Nukui, S; Omura, A; Kawamura, M Bioorg Med Chem Lett 17: 5533-6 (2007)
- Axford, L; Boot, JR; Hotten, TM; Keenan, M; Martin, FM; Milutinovic, S; Moore, NA; O'Neill, MF; Pullar, IA; Tupper, DE; Van Belle, KR; Vivien, V Bioorg Med Chem Lett 13: 3277-80 (2003)
- She, X; Pegoli, A; Gruber, CG; Wifling, D; Carpenter, J; Hübner, H; Chen, M; Wan, J; Bernhardt, G; Gmeiner, P; Holliday, ND; Keller, M J Med Chem 63: 4133-4154 (2020)
- Jones, A; Kemp, M; Stockley, M; Gibson, K; Whitlock, G US Patent US11053198 (2021)
- Bezençon, O; Heidmann, B; Siegrist, R; Stamm, S; Richard, S; Pozzi, D; Corminboeuf, O; Roch, C; Kessler, M; Ertel, EA; Reymond, I; Pfeifer, T; de Kanter, R; Toeroek-Schafroth, M; Moccia, LG; Mawet, J; Moon, R; Rey, M; Capeleto, B; Fournier, E J Med Chem 60: 9769-9789 (2017)
- Iraji, A; Nouri, A; Edraki, N; Pirhadi, S; Khoshneviszadeh, M; Khoshneviszadeh, M Bioorg Med Chem 28: (2020)
- Kobe, A; Caaveiro, JM; Tashiro, S; Kajihara, D; Kikkawa, M; Mitani, T; Tsumoto, K J Med Chem 56: 2155-9 (2013)
- Ahn, JH; Kim, H; Suh, J; Lee, I; Kim, K; Park, K; Bae, EJ; Shong, KE; Pagire, SH; Lim, A; Jeon, J; Pagire, HS; Zhang, H; Kim, M; Pyo, J US Patent US11407763 (2022)
- Gilbert, AM; Kirisits, M; Toy, P; Nunn, DS; Failli, A; Dushin, EG; Novikova, E; Petersen, PJ; Joseph-McCarthy, D; McFadyen, I; Fritz, CC Bioorg Med Chem Lett 14: 37-41 (2003)
- Chen, HY; Plummer, CW; Xiao, D; Chobanian, HR; DeMong, D; Miller, M; Trujillo, ME; Kirkland, M; Kosinski, D; Mane, J; Pachanski, M; Cheewatrakoolpong, B; Di Salvo, J; Thomas-Fowlkes, B; Souza, S; Tatosian, DA; Chen, Q; Hafey, MJ; Houle, R; Nolting, AF; Orr, R; Ehrhart, J; Weinglass, AB; Tschirret-Guth, R; Howard, AD; Colletti, SL ACS Med Chem Lett 9: 685-690 (2018)
- Fallacara, AL; Passannanti, R; Mori, M; Iovenitti, G; Musumeci, F; Greco, C; Crespan, E; Kissova, M; Maga, G; Tarantelli, C; Spriano, F; Gaudio, E; Bertoni, F; Botta, M; Schenone, S Eur J Med Chem 181: (2019)
- Lehr, M; Klimt, M; Elfringhoff, AS Bioorg Med Chem Lett 11: 2569-72 (2001)
- Fyfe, MC; Knaggs, M; Meghani, P; Thom, SM US Patent US9796742 (2017)
- Gazvoda, M; Beranic, N; Turk, S; Burja, B; Kocevar, M; Rižner, TL; Gobec, S; Polanc, S Eur J Med Chem 62: 89-97 (2013)
- Ebiike, H; Taka, N; Matsushita, M; Ohmori, M; Takami, K; Hyohdoh, I; Kohchi, M; Hayase, T; Nishii, H; Morikami, K; Nakanishi, Y; Akiyama, N; Shindoh, H; Ishii, N; Isobe, T; Matsuoka, H J Med Chem 59: 10586-10600 (2016)
- Gentry, PR; Kokubo, M; Bridges, TM; Kett, NR; Harp, JM; Cho, HP; Smith, E; Chase, P; Hodder, PS; Niswender, CM; Daniels, JS; Conn, PJ; Wood, MR; Lindsley, CW J Med Chem 56: 9351-5 (2013)
- Coteron, JM; Marco, M; Esquivias, J; Deng, X; White, KL; White, J; Koltun, M; El Mazouni, F; Kokkonda, S; Katneni, K; Bhamidipati, R; Shackleford, DM; Angulo-Barturen, I; Ferrer, SB; Jiménez-Díaz, MB; Gamo, FJ; Goldsmith, EJ; Charman, WN; Bathurst, I; Floyd, D; Matthews, D; Burrows, JN; Rathod, PK; Charman, SA; Phillips, MA J Med Chem 54: 5540-61 (2011)
- Klar, U; Koppitz, M; Kosemund, D; Bohlmann, R; Bader, B; Lienau, P; Siemeister, G; Prechtl, S; Nguyen, D; Scott, W US Patent US9468642 (2016)
- Wichur, T; Pasieka, A; Gody?, J; Panek, D; Góral, I; Latacz, G; Honkisz-Orzechowska, E; Bucki, A; Siwek, A; G?uch-Lutwin, M; Knez, D; Brazzolotto, X; Gobec, S; Ko?aczkowski, M; Sabate, R; Malawska, B; Wi?ckowska, A Eur J Med Chem 225: (2021)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Kumaran, D; Adler, M; Levit, M; Krebs, M; Sweeney, R; Swaminathan, S Bioorg Med Chem 23: 7264-73 (2015)
- Pedreira, JGB; Nahidino, P; Kudolo, M; Pantsar, T; Berger, BT; Forster, M; Knapp, S; Laufer, S; Barreiro, EJ J Med Chem 63: 7347-7354 (2020)
- Winter-Holt, JJ; Bardelle, C; Chiarparin, E; Dale, IL; Davey, PRJ; Davies, NL; Denz, C; Fillery, SM; Guérot, CM; Han, F; Hughes, SJ; Kulkarni, M; Liu, Z; Milbradt, A; Moss, TA; Niu, H; Patel, J; Rabow, AA; Schimpl, M; Shi, J; Sun, D; Yang, D; Guichard, S J Med Chem 65: 3306-3331 (2022)
- Tomic, M; Kundakovic, M; Butorovic, B; Janac, B; Andric, D; Roglic, G; Ignjatovic, D; Kostic-Rajacic, S Bioorg Med Chem Lett 14: 4263-6 (2004)
- Burns, CJ; Harte, MF; Bu, X; Fantino, E; Giarrusso, M; Joffe, M; Kurek, M; Legge, FS; Razzino, P; Su, S; Treutlein, H; Wan, SS; Zeng, J; Wilks, AF Bioorg Med Chem Lett 19: 1206-9 (2009)
- Misawa, T; Yorioka, M; Demizu, Y; Noguchi-Yachide, T; Ohoka, N; Kurashima-Kinoshita, M; Motoyoshi, H; Nojiri, H; Kittaka, A; Makishima, M; Naito, M; Kurihara, M Bioorg Med Chem Lett 25: 5362-6 (2015)
- Shimazawa, R; Kuriyama, M; Shirai, R Bioorg Med Chem Lett 18: 3350-3 (2008)
- Yamamoto, S; Kurono, M; Yoshida, A; Hotta, S US Patent US11052091 (2021)
- Syrjänen, L; Kuuslahti, M; Tolvanen, M; Vullo, D; Parkkila, S; Supuran, CT Bioorg Med Chem 23: 2303-9 (2015)
- Borsari, C; Jiménez-Antón, MD; Eick, J; Bifeld, E; Torrado, JJ; Olías-Molero, AI; Corral, MJ; Santarem, N; Baptista, C; Severi, L; Gul, S; Wolf, M; Kuzikov, M; Ellinger, B; Reinshagen, J; Witt, G; Linciano, P; Tait, A; Costantino, L; Luciani, R; Tejera Nevado, P; Zander-Dinse, D; Franco, CH; Ferrari, S; Moraes, CB; Cordeiro-da-Silva, A; Ponterini, G; Clos, J; Alunda, JM; Costi, MP Eur J Med Chem 183: (2019)
- Köse, M; Ritter, K; Thiemke, K; Gillard, M; Kostenis, E; Müller, CE ACS Med Chem Lett 5: 326-30 (2014)
- Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Bioorg Med Chem Lett 22: 5966-70 (2012)
- Wijtmans, M; Verzijl, D; Bergmans, S; Lai, M; Bosch, L; Smit, MJ; de Esch, IJ; Leurs, R Bioorg Med Chem 19: 3384-93 (2011)
- Lamothe, M; Perrin, D; Blotières, D; Leborgne, M; Gras, S; Bonnet, D; Hill, BT; Halazy, S Bioorg Med Chem Lett 6: 1291-1296 (1996)
- Lu, Q; Chen, Z; Perumattam, J; Wang, DX; Liang, W; Xu, YJ; Do, S; Bonaga, L; Higaki, J; Dong, H; Liclican, A; Sideris, S; Laney, M; Dugar, S; Mavunkel, B; Levy, DE Bioorg Med Chem Lett 18: 2399-403 (2008)
- Cappelli, A; Manini, M; Valenti, S; Castriconi, F; Giuliani, G; Anzini, M; Brogi, S; Butini, S; Gemma, S; Campiani, G; Giorgi, G; Mennuni, L; Lanza, M; Giordani, A; Caselli, G; Letari, O; Makovec, F Eur J Med Chem 63: 85-94 (2013)
- Sweis, RF; Hunt, JA; Sinclair, PJ; Chen, Y; Eveland, SS; Guo, Q; Hyland, SA; Milot, DP; Cumiskey, AM; Latham, M; Rosa, R; Peterson, L; Sparrow, CP; Anderson, MS Bioorg Med Chem Lett 21: 2597-600 (2011)
- Pascard, C; Guilhem, J; Vincent, M; Rémond, G; Portevin, B; Laubie, M J Med Chem 34: 663-9 (1991)
- Furber, M; Alcaraz, L; Bent, JE; Beyerbach, A; Bowers, K; Braddock, M; Caffrey, MV; Cladingboel, D; Collington, J; Donald, DK; Fagura, M; Ince, F; Kinchin, EC; Laurent, C; Lawson, M; Luker, TJ; Mortimore, MM; Pimm, AD; Riley, RJ; Roberts, N; Robertson, M; Theaker, J; Thorne, PV; Weaver, R; Webborn, P; Willis, P J Med Chem 50: 5882-5 (2007)
- Buzard, DJ; Lopez, L; Moody, J; Kawasaki, A; Schrader, TO; Kasem, M; Johnson, B; Zhu, X; Thoresen, L; Kim, SH; Gharbaoui, T; Sengupta, D; Calvano, L; Krishnan, A; Gao, Y; Semple, G; Edwards, J; Barden, J; Morgan, M; Usmani, K; Chen, C; Sadeque, A; Chen, W; Christopher, RJ; Thatte, J; Fu, L; Solomon, M; Whelan, K; Al-Shamma, H; Gatlin, J; Gaidarov, I; Anthony, T; Le, M; Unett, DJ; Stirn, S; Blackburn, A; Behan, DP; Jones, RM ACS Med Chem Lett 5: 1334-9 (2014)
- Beveridge, RE; Wallweber, HA; Ashkenazi, A; Beresini, M; Clark, KR; Gibbons, P; Ghiro, E; Kaufman, S; Larivée, A; Leblanc, M; Leclerc, JP; Lemire, A; Ly, C; Rudolph, J; Schwarz, JB; Srivastava, S; Wang, W; Zhao, L; Braun, MG ACS Med Chem Lett 11: 2389-2396 (2020)
- Lamothe, M; Perrin, D; Blotières, D; Leborgne, M; Gras, S; Bonnet, D; Hill, BT; Halazy, S Bioorg Med Chem Lett 6: 1291-1296 (1996)
- Lefrançois, M; Lefebvre, MR; Saint-Onge, G; Boulais, PE; Lamothe, S; Leduc, R; Lavigne, P; Heveker, N; Escher, E ACS Med Chem Lett 2: 597-602 (2011)
- Lehr, M; Klimt, M; Elfringhoff, AS Bioorg Med Chem Lett 11: 2569-72 (2001)
- Li, M; Konteatis, Z; Nagaraja, N; Chen, Y; Zhou, S; Ma, G; Gross, S; Marjon, K; Hyer, ML; Mandley, E; Lein, M; Padyana, AK; Jin, L; Tong, S; Peters, R; Murtie, J; Travins, J; Medeiros, M; Liu, P; Frank, V; Judd, ET; Biller, SA; Marks, KM; Sui, Z; Reznik, SK J Med Chem 65: 4600-4615 (2022)
- Leopoldo, M; Lacivita, E; De Giorgio, P; Fracasso, C; Guzzetti, S; Caccia, S; Contino, M; Colabufo, NA; Berardi, F; Perrone, R J Med Chem 51: 5813-22 (2008)
- Liégeois, JF; Lespagnard, M; Meneses Salas, E; Mangin, F; Scuvée-Moreau, J; Dilly, S ACS Med Chem Lett 5: 358-62 (2014)
- Gajewski, TF; Spranger, S; Leung, M US Patent US10967060 (2021)
- Benaim, G; Sanders, JM; Garcia-Marchán, Y; Colina, C; Lira, R; Caldera, AR; Payares, G; Sanoja, C; Burgos, JM; Leon-Rossell, A; Concepcion, JL; Schijman, AG; Levin, M; Oldfield, E; Urbina, JA J Med Chem 49: 892-9 (2006)
- Kumaran, D; Adler, M; Levit, M; Krebs, M; Sweeney, R; Swaminathan, S Bioorg Med Chem 23: 7264-73 (2015)
- Li, M; Lin, Z; Johnson, ME Bioorg Med Chem Lett 9: 1957-62 (1999)
- Huryn, DM; Wipf, P; LaPorte, MG; Colombo, R; Kovaliov, M; Lim, C; Alverez, CN; Yue, Z; Samankumara, LP; Chatterley, AJ; Yan, Y; Liang, M; Green, NJ; Baldwin, ET; Moore, WJ; Arkin, M; Neitz, RJ; Ang, K; Bryant, C; Bulfer, S US Patent US11247985 (2022)
- Liao, M; Zhang, J; Wang, G; Wang, L; Liu, J; Ouyang, L; Liu, B J Med Chem 64: 2382-2418 (2021)
- Kozlova, A; Thabault, L; Dauguet, N; Deskeuvre, M; Stroobant, V; Pilotte, L; Liberelle, M; Van den Eynde, B; Frédérick, R Eur J Med Chem 227: (2022)
- Burger, MT; Han, W; Lan, J; Nishiguchi, G; Bellamacina, C; Lindval, M; Atallah, G; Ding, Y; Mathur, M; McBride, C; Beans, EL; Muller, K; Tamez, V; Zhang, Y; Huh, K; Feucht, P; Zavorotinskaya, T; Dai, Y; Holash, J; Castillo, J; Langowski, J; Wang, Y; Chen, MY; Garcia, PD ACS Med Chem Lett 4: 1193-7 (2013)
- Lingel, A; Sendzik, M; Huang, Y; Shultz, MD; Cantwell, J; Dillon, MP; Fu, X; Fuller, J; Gabriel, T; Gu, J; Jiang, X; Li, L; Liang, F; McKenna, M; Qi, W; Rao, W; Sheng, X; Shu, W; Sutton, J; Taft, B; Wang, L; Zeng, J; Zhang, H; Zhang, M; Zhao, K; Lindvall, M; Bussiere, DE J Med Chem 60: 415-427 (2017)
- Wang, A; Lv, K; Tao, Z; Gu, J; Fu, L; Liu, M; Wan, B; Franzblau, SG; Ma, C; Ma, X; Han, B; Wang, A; Xu, S; Lu, Y Eur J Med Chem 181: (2019)
- Camps, P; Formosa, X; Galdeano, C; Gómez, T; Muñoz-Torrero, D; Scarpellini, M; Viayna, E; Badia, A; Clos, MV; Camins, A; Pallàs, M; Bartolini, M; Mancini, F; Andrisano, V; Estelrich, J; Lizondo, M; Bidon-Chanal, A; Luque, FJ J Med Chem 51: 3588-98 (2008)
- Collin, M; Brohm, D; Héroult, M; Lobell, M; Hübsch, W; Lustig, K; Grünewald, S; Bömer, U; Vöhringer, V; Lindner, N US Patent US9598416 (2017)
- Zhou, C; Garcia-Calvo, M; Pinto, S; Lombardo, M; Feng, Z; Bender, K; Pryor, KD; Bhatt, UR; Chabin, RM; Geissler, WM; Shen, Z; Tong, X; Zhang, Z; Wong, KK; Roy, RS; Chapman, KT; Yang, L; Xiong, Y J Med Chem 53: 7251-63 (2010)
- Singer, M; Lopez, M; Bornaghi, LF; Innocenti, A; Vullo, D; Supuran, CT; Poulsen, SA Bioorg Med Chem Lett 19: 2273-6 (2009)
- Huang, A; Moretto, A; Janz, K; Lowe, M; Bedard, PW; Tam, S; Di, L; Clerin, V; Sushkova, N; Tchernychev, B; Tsao, DH; Keith, JC; Shaw, GD; Schaub, RG; Wang, Q; Kaila, N J Med Chem 53: 6003-17 (2010)
- Tian, C; Yang, C; Wu, T; Lu, M; Chen, Y; Yang, Y; Liu, X; Ling, Y; Deng, M; Jia, Y; Zhou, Y Bioorg Med Chem Lett 48: (2021)
- Butler, KV; Ma, A; Yu, W; Li, F; Tempel, W; Babault, N; Pittella-Silva, F; Shao, J; Wang, J; Luo, M; Vedadi, M; Brown, PJ; Arrowsmith, CH; Jin, J J Med Chem 59: 9881-9889 (2016)
- Stahlecker, J; Klett, T; Schwer, M; Jaag, S; Dammann, M; Ernst, LN; Braun, MB; Zimmermann, MO; Kramer, M; Lämmerhofer, M; Stehle, T; Coles, M; Boeckler, FM RSC Med Chem 13: 1575-1586 (2022)
- A., AK; Irina, CM; M., HD; C., KJ; Jian, L; J., MP; L., RV; T., RM; A., SC; Zhe, W; Dong, X WIPO WO2022094012 (2022)
- J., BM; E., FM; Marie, LH; J., MJ; J., RA; M., SK; J., SS WIPO WO2022115301 (2022)
- Mjalli, AM; Chapman, KT; MacCoss, M; Thornberry, NA Bioorg Med Chem Lett 3: 2689-2692 (1993)
- van der Stelt, M; van Kuik, JA; Bari, M; van Zadelhoff, G; Leeflang, BR; Veldink, GA; Finazzi-Agrò, A; Vliegenthart, JF; Maccarrone, M J Med Chem 45: 3709-20 (2002)
- Sasaki, S; Ehara, T; Alam, MR; Fujino, Y; Harada, N; Kimura, J; Nakamura, H; Maeda, M Bioorg Med Chem Lett 11: 2581-4 (2001)
- Carballa, DM; Seoane, S; Zacconi, F; Pérez, X; Rumbo, A; Alvarez-Díaz, S; Larriba, MJ; Pérez-Fernández, R; Muñoz, A; Maestro, M; Mouriño, A; Torneiro, M J Med Chem 55: 8642-56 (2012)
- Di Fabio, R; Micheli, F; Alvaro, G; Cavanni, P; Donati, D; Gagliardi, T; Fontana, G; Giovannini, R; Maffeis, M; Mingardi, A; Tranquillini, ME; Vitulli, G Bioorg Med Chem Lett 17: 2254-9 (2007)
- Manetti, F; Brullo, C; Magnani, M; Mosci, F; Chelli, B; Crespan, E; Schenone, S; Naldini, A; Bruno, O; Trincavelli, ML; Maga, G; Carraro, F; Martini, C; Bondavalli, F; Botta, M J Med Chem 51: 1252-9 (2008)
- Nishiyama, Y; Mori, S; Makishima, M; Fujii, S; Kagechika, H; Hashimoto, Y; Ishikawa, M ACS Med Chem Lett 9: 641-645 (2018)
- Reilly, SW; Puentes, LN; Wilson, K; Hsieh, CJ; Weng, CC; Makvandi, M; Mach, RH J Med Chem 61: 5367-5379 (2018)
- Castillo, M; Forns, P; Erra, M; Mir, M; López, M; Maldonado, M; Orellana, A; Carreño, C; Ramis, I; Miralpeix, M; Vidal, B Bioorg Med Chem Lett 22: 5419-23 (2012)
- Rovnyak, GC; Kimball, SD; Beyer, B; Cucinotta, G; DiMarco, JD; Gougoutas, J; Hedberg, A; Malley, M; McCarthy, JP; Zhang, R J Med Chem 38: 119-29 (1995)
- Sundén, H; Schäfer, A; Scheepstra, M; Leysen, S; Malo, M; Ma, JN; Burstein, ES; Ottmann, C; Brunsveld, L; Olsson, R J Med Chem 59: 1232-8 (2016)
- Cappelli, A; Manini, M; Paolino, M; Gallelli, A; Anzini, M; Mennuni, L; Del Cadia, M; De Rienzo, F; Menziani, MC; Vomero, S ACS Med Chem Lett 2: 571-576 (2011)
- Manning, M; Cheng, LL; Klis, WA; Balaspiri, L; Olma, A; Sawyer, WH; Wo, NC; Chan, WY J Med Chem 38: 1762-9 (1995)
- Manzoni, L; Gornati, D; Manzotti, M; Cairati, S; Bossi, A; Arosio, D; Lecis, D; Seneci, P Bioorg Med Chem Lett 26: 4613-4619 (2016)
- Ahn, JS; Radhakrishnan, ML; Mapelli, M; Choi, S; Tidor, B; Cuny, GD; Musacchio, A; Yeh, LA; Kosik, KS Chem Biol 12: 811-23 (2005)
- Coteron, JM; Marco, M; Esquivias, J; Deng, X; White, KL; White, J; Koltun, M; El Mazouni, F; Kokkonda, S; Katneni, K; Bhamidipati, R; Shackleford, DM; Angulo-Barturen, I; Ferrer, SB; Jiménez-Díaz, MB; Gamo, FJ; Goldsmith, EJ; Charman, WN; Bathurst, I; Floyd, D; Matthews, D; Burrows, JN; Rathod, PK; Charman, SA; Phillips, MA J Med Chem 54: 5540-61 (2011)
- Amori, L; Serpi, M; Marinozzi, M; Costantino, G; Diaz, MG; Hermit, MB; Thomsen, C; Pellicciari, R Bioorg Med Chem Lett 16: 196-9 (2005)
- Palanki, MS; Dneprovskaia, E; Doukas, J; Fine, RM; Hood, J; Kang, X; Lohse, D; Martin, M; Noronha, G; Soll, RM; Wrasidlo, W; Yee, S; Zhu, H J Med Chem 50: 4279-94 (2007)
- Blake, JF; Burkard, M; Chan, J; Chen, H; Chou, KJ; Diaz, D; Dudley, DA; Gaudino, JJ; Gould, SE; Grina, J; Hunsaker, T; Liu, L; Martinson, M; Moreno, D; Mueller, L; Orr, C; Pacheco, P; Qin, A; Rasor, K; Ren, L; Robarge, K; Shahidi-Latham, S; Stults, J; Sullivan, F; Wang, W; Yin, J; Zhou, A; Belvin, M; Merchant, M; Moffat, J; Schwarz, JB J Med Chem 59: 5650-60 (2016)
- Tormählen, NM; Martorelli, M; Kuhn, A; Maier, F; Guezguez, J; Burnet, M; Albrecht, W; Laufer, SA; Koch, P J Med Chem 65: 1225-1242 (2022)
- Shimizu, K; Maruyama, M; Yasui, Y; Minegishi, H; Ban, HS; Nakamura, H Bioorg Med Chem Lett 20: 1453-6 (2010)
- Lavecchia, A; Di Giovanni, C; Pesapane, A; Montuori, N; Ragno, P; Martucci, NM; Masullo, M; De Vendittis, E; Novellino, E J Med Chem 55: 4142-58 (2012)
- Burger, MT; Han, W; Lan, J; Nishiguchi, G; Bellamacina, C; Lindval, M; Atallah, G; Ding, Y; Mathur, M; McBride, C; Beans, EL; Muller, K; Tamez, V; Zhang, Y; Huh, K; Feucht, P; Zavorotinskaya, T; Dai, Y; Holash, J; Castillo, J; Langowski, J; Wang, Y; Chen, MY; Garcia, PD ACS Med Chem Lett 4: 1193-7 (2013)
- Mejdrová, I; Chalupská, D; Placková, P; Müller, C; ?ála, M; Klíma, M; Baumlová, A; Hrebabecký, H; Procházková, E; Dejmek, M; Strunin, D; Weber, J; Lee, G; Matou?ová, M; Mertlíková-Kaiserová, H; Ziebuhr, J; Birkus, G; Boura, E; Nencka, R J Med Chem 60: 100-118 (2017)
- Tamamura, H; Omagari, A; Hiramatsu, K; Gotoh, K; Kanamoto, T; Xu, Y; Kodama, E; Matsuoka, M; Hattori, T; Yamamoto, N; Nakashima, H; Otaka, A; Fujii, N Bioorg Med Chem Lett 11: 1897-902 (2001)
- Ebiike, H; Taka, N; Matsushita, M; Ohmori, M; Takami, K; Hyohdoh, I; Kohchi, M; Hayase, T; Nishii, H; Morikami, K; Nakanishi, Y; Akiyama, N; Shindoh, H; Ishii, N; Isobe, T; Matsuoka, H J Med Chem 59: 10586-10600 (2016)
- Marino, JP; Fisher, PW; Hofmann, GA; Kirkpatrick, RB; Janson, CA; Johnson, RK; Ma, C; Mattern, M; Meek, TD; Ryan, MD; Schulz, C; Smith, WW; Tew, DG; Tomazek, TA; Veber, DF; Xiong, WC; Yamamoto, Y; Yamashita, K; Yang, G; Thompson, SK J Med Chem 50: 3777-85 (2007)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Kumar, S; Waldo, J; Jaipuri, F; Mautino, M US Patent US9981973 (2018)
- Qiu, W; Zhou, M; Mazumdar, M; Azzi, A; Ghanmi, D; Luu-The, V; Labrie, F; Lin, SX J Biol Chem 282: 8368-79 (2007)
- Lingel, A; Sendzik, M; Huang, Y; Shultz, MD; Cantwell, J; Dillon, MP; Fu, X; Fuller, J; Gabriel, T; Gu, J; Jiang, X; Li, L; Liang, F; McKenna, M; Qi, W; Rao, W; Sheng, X; Shu, W; Sutton, J; Taft, B; Wang, L; Zeng, J; Zhang, H; Zhang, M; Zhao, K; Lindvall, M; Bussiere, DE J Med Chem 60: 415-427 (2017)
- Li, M; Konteatis, Z; Nagaraja, N; Chen, Y; Zhou, S; Ma, G; Gross, S; Marjon, K; Hyer, ML; Mandley, E; Lein, M; Padyana, AK; Jin, L; Tong, S; Peters, R; Murtie, J; Travins, J; Medeiros, M; Liu, P; Frank, V; Judd, ET; Biller, SA; Marks, KM; Sui, Z; Reznik, SK J Med Chem 65: 4600-4615 (2022)
- Jia, ZJ; Venkataramani, C; Huang, W; Mehrotra, M; Song, Y; Xu, Q; Bauer, SM; Rose, JW; Kane, B; Pandey, A US Patent US9579320 (2017)
- Vanotti, E; Caldarelli, M; Cirla, A; Forte, B; Ermoli, A; Menichincheri, M; Pillan, A; Scolaro, A US Patent US9670191 (2017)
- Blake, JF; Burkard, M; Chan, J; Chen, H; Chou, KJ; Diaz, D; Dudley, DA; Gaudino, JJ; Gould, SE; Grina, J; Hunsaker, T; Liu, L; Martinson, M; Moreno, D; Mueller, L; Orr, C; Pacheco, P; Qin, A; Rasor, K; Ren, L; Robarge, K; Shahidi-Latham, S; Stults, J; Sullivan, F; Wang, W; Yin, J; Zhou, A; Belvin, M; Merchant, M; Moffat, J; Schwarz, JB J Med Chem 59: 5650-60 (2016)
- Okolotowicz, KJ; Dwyer, M; Ryan, D; Cheng, J; Cashman, EA; Moore, S; Mercola, M; Cashman, JR Bioorg Med Chem 26: 4441-4451 (2018)
- Cutshall, NS; Gage, JL; Gruswitz, FA; Khalaf, J; Little, TL; Metz, M; Nguyen, JH; Nollert von Specht, PK; Tsoung, J; Cicirelli, M; Goldstein, SR; Keshipeddy, SK; Kwon, DY; Lemus, RH; Vaddela, SB US Patent US11584714 (2023)
- Kontopidis, G; McInnes, C; Pandalaneni, SR; McNae, I; Gibson, D; Mezna, M; Thomas, M; Wood, G; Wang, S; Walkinshaw, MD; Fischer, PM Chem Biol 13: 201-11 (2006)
- Brauers, G; Edrada, RA; Ebel, R; Proksch, P; Wray, V; Berg, A; Gräfe, U; Schächtele, C; Totzke, F; Finkenzeller, G; Marme, D; Kraus, J; Münchbach, M; Michel, M; Bringmann, G; Schaumann, K J Nat Prod 63: 739-45 (2000)
- Michels, M; Briem, H; Vakalopoulos, A; Zimmermann, K; Teusch, N US Patent US8604028 (2013)
- Chen, HY; Plummer, CW; Xiao, D; Chobanian, HR; DeMong, D; Miller, M; Trujillo, ME; Kirkland, M; Kosinski, D; Mane, J; Pachanski, M; Cheewatrakoolpong, B; Di Salvo, J; Thomas-Fowlkes, B; Souza, S; Tatosian, DA; Chen, Q; Hafey, MJ; Houle, R; Nolting, AF; Orr, R; Ehrhart, J; Weinglass, AB; Tschirret-Guth, R; Howard, AD; Colletti, SL ACS Med Chem Lett 9: 685-690 (2018)
- Ma, B; Metrick, CM; Gu, C; Hoemberger, M; Bajrami, B; Bame, E; Huang, J; Mingueneau, M; Murugan, P; Santoro, JC; Tang, H; Wang, T; Hopkins, BT Bioorg Med Chem Lett 60: (2022)
- Castillo, M; Forns, P; Erra, M; Mir, M; López, M; Maldonado, M; Orellana, A; Carreño, C; Ramis, I; Miralpeix, M; Vidal, B Bioorg Med Chem Lett 22: 5419-23 (2012)
- Fardis, M; Jin, H; Jabri, S; Cai, RZ; Mish, M; Tsiang, M; Kim, CU Bioorg Med Chem Lett 16: 4031-5 (2006)
- Fushimi, M; Fujimori, I; Wakabayashi, T; Hasui, T; Kawakita, Y; Imamura, K; Kato, T; Murakami, M; Ishii, T; Kikko, Y; Kasahara, M; Nakatani, A; Hiura, Y; Miyamoto, M; Saikatendu, K; Zou, H; Lane, SW; Lawson, JD; Imoto, H J Med Chem 62: 4915-4935 (2019)
- Kashima, Y; Miyazawa, M Bioorg Med Chem Lett 23: 6580-4 (2013)
- Zhang, X; Rueter, JK; Chen, Y; Moorjani, M; Lanier, MC; Lin, E; Gross, RS; Tellew, JE; Williams, JP; Lechner, SM; Markison, S; Joswig, T; Malany, S; Santos, M; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Saunders, J; Slee, DH Bioorg Med Chem Lett 18: 1778-83 (2008)
- Castelli, R; Taranto, S; Furiassi, L; Bozza, N; Marseglia, G; Ferlenghi, F; Rivara, S; Retini, M; Bedini, A; Spadoni, G; Matarazzo, S; Ronca, R; Presta, M; Mor, M; Giacomini, A Eur J Med Chem 221: (2021)
- Carr&aagrovr;, G; Rizzi, A; Guerrini, R; Barnes, TA; McDonald, J; Hebbes, CP; Mela, F; Kenigs, VA; Marzola, G; Rizzi, D; Gavioli, E; Zucchini, S; Regoli, D; Morari, M; Salvadori, S; Rowbotham, DJ; Lambert, DG; Kapusta, DR; Calo', G J Pharmacol Exp Ther 312: 1114-23 (2005)
- Buzard, DJ; Lopez, L; Moody, J; Kawasaki, A; Schrader, TO; Kasem, M; Johnson, B; Zhu, X; Thoresen, L; Kim, SH; Gharbaoui, T; Sengupta, D; Calvano, L; Krishnan, A; Gao, Y; Semple, G; Edwards, J; Barden, J; Morgan, M; Usmani, K; Chen, C; Sadeque, A; Chen, W; Christopher, RJ; Thatte, J; Fu, L; Solomon, M; Whelan, K; Al-Shamma, H; Gatlin, J; Gaidarov, I; Anthony, T; Le, M; Unett, DJ; Stirn, S; Blackburn, A; Behan, DP; Jones, RM ACS Med Chem Lett 5: 1334-9 (2014)
- Fallacara, AL; Passannanti, R; Mori, M; Iovenitti, G; Musumeci, F; Greco, C; Crespan, E; Kissova, M; Maga, G; Tarantelli, C; Spriano, F; Gaudio, E; Bertoni, F; Botta, M; Schenone, S Eur J Med Chem 181: (2019)
- Cirillo, PF; Hickey, ER; Moss, N; Breitfelder, S; Betageri, R; Fadra, T; Gaenzler, F; Gilmore, T; Goldberg, DR; Kamhi, V; Kirrane, T; Kroe, RR; Madwed, J; Moriak, M; Netherton, M; Pargellis, CA; Patel, UR; Qian, KC; Sharma, R; Sun, S; Swinamer, A; Torcellini, C; Takahashi, H; Tsang, M; Xiong, Z Bioorg Med Chem Lett 19: 2386-91 (2009)
- Desjardins, M; Desgagnes, J; Lacoste, L; Yang, F; Morin, M; Lapointe, J; Chenevert, R Bioorg Med Chem Lett 7: 2363-2366 (1997)
- Inoue, T; Morita, M; Tojo, T; Nagashima, A; Moritomo, A; Miyake, H Bioorg Med Chem 21: 3873-81 (2013)
- Ito, M; Sakamoto, T; Suzuki, T; Egashira, S; Moriya, M; Ishihara, A; Iwaasa, H; Matsushita, H; Nakase, K; Wallace, MA; Dean, D; Sato, N; Tokita, S; Kanatani, A Bioorg Med Chem Lett 19: 2835-9 (2009)
- Johnson, DS; Stiff, C; Lazerwith, SE; Kesten, SR; Fay, LK; Morris, M; Beidler, D; Liimatta, MB; Smith, SE; Dudley, DT; Sadagopan, N; Bhattachar, SN; Kesten, SJ; Nomanbhoy, TK; Cravatt, BF; Ahn, K ACS Med Chem Lett 2: 91-96 (2011)
- Cee, VJ; Albrecht, BK; Geuns-Meyer, S; Hughes, P; Bellon, S; Bready, J; Caenepeel, S; Chaffee, SC; Coxon, A; Emery, M; Fretland, J; Gallant, P; Gu, Y; Hodous, BL; Hoffman, D; Johnson, RE; Kendall, R; Kim, JL; Long, AM; McGowan, D; Morrison, M; Olivieri, PR; Patel, VF; Polverino, A; Powers, D; Rose, P; Wang, L; Zhao, H J Med Chem 50: 627-40 (2007)
- Ali, SM; Ashwell, MA; Kelleher, E; Koerner, S; Lapierre, J; Link, JS; Liu, Y; Moussa, M; Palma, R; Tandon, M; Vensel, D; Westlund, N; Wu, H; Yang, R US Patent US8541407 (2013)
- Wu, S; Vossius, S; Rahmouni, S; Miletic, AV; Vang, T; Vazquez-Rodriguez, J; Cerignoli, F; Arimura, Y; Williams, S; Hayes, T; Moutschen, M; Vasile, S; Pellecchia, M; Mustelin, T; Tautz, L J Med Chem 52: 6716-23 (2009)
- Meegalla, SK; Plössl, K; Kung, MP; Stevenson, DA; Mu, M; Kushner, S; Liable-Sands, LM; Rheingold, AL; Kung, HF J Med Chem 41: 428-36 (1998)
- D'Agostino, LA; Sjin, RT; Niu, D; McDonald, JJ; Zhu, Z; Liu, H; Mazdiyasni, H; Petter, RC; Singh, J; Barrague, M; Gross, A; Munson, M US Patent US9695132 (2017)
- Sakamoto, T; Koga, Y; Hikota, M; Matsuki, K; Murakami, M; Kikkawa, K; Fujishige, K; Kotera, J; Omori, K; Morimoto, H; Yamada, K Bioorg Med Chem Lett 24: 5175-80 (2014)
- Toda, N; Hao, X; Ogawa, Y; Oda, K; Yu, M; Fu, Z; Chen, Y; Kim, Y; Lizarzaburu, M; Lively, S; Lawlis, S; Murakoshi, M; Nara, F; Watanabe, N; Reagan, JD; Tian, H; Fu, A; Motani, A; Liu, Q; Lin, YJ; Zhuang, R; Xiong, Y; Fan, P; Medina, J; Li, L; Izumi, M; Okuyama, R; Shibuya, S ACS Med Chem Lett 4: 790-4 (2013)
- Ban, H; Muraoka, M; Ioriya, K; Ohashi, N Bioorg Med Chem Lett 16: 44-8 (2005)
- Misawa, T; Yorioka, M; Demizu, Y; Noguchi-Yachide, T; Ohoka, N; Kurashima-Kinoshita, M; Motoyoshi, H; Nojiri, H; Kittaka, A; Makishima, M; Naito, M; Kurihara, M Bioorg Med Chem Lett 25: 5362-6 (2015)
- Anami, Y; Sakamaki, Y; Itoh, T; Inaba, Y; Nakabayashi, M; Ikura, T; Ito, N; Yamamoto, K Bioorg Med Chem 23: 7274-81 (2015)
- Yoshikawa, M; Saitoh, M; Katoh, T; Seki, T; Bigi, SV; Shimizu, Y; Ishii, T; Okai, T; Kuno, M; Hattori, H; Watanabe, E; Saikatendu, KS; Zou, H; Nakakariya, M; Tatamiya, T; Nakada, Y; Yogo, T J Med Chem 61: 2384-2409 (2018)
- Kolasa, T; Matulenko, MA; Hakeem, AA; Patel, MV; Mortell, K; Bhatia, P; Henry, R; Nakane, M; Hsieh, GC; Terranova, MA; Uchic, ME; Miller, LN; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, B; El Kouhen, O; Marsh, KC; Wetter, JM; Moreland, RB; Brioni, JD; Stewart, AO J Med Chem 49: 5093-109 (2006)
- Koike, T; Takai, T; Hoashi, Y; Nakayama, M; Kosugi, Y; Nakashima, M; Yoshikubo, S; Hirai, K; Uchikawa, O J Med Chem 54: 4207-18 (2011)
- Kobayashi, T; Sasaki, S; Tomita, N; Fukui, S; Kuroda, N; Nakayama, M; Kiba, A; Takatsu, Y; Ohtaki, T; Itoh, F; Baba, A Bioorg Med Chem 18: 3841-59 (2010)
- Nakazono, M; Hasegawa, S; Yamamoto, T; Zaitsu, K Bioorg Med Chem Lett 14: 5619-21 (2004)
- Morera, E; Di Marzo, V; Monti, L; Allarŕ, M; Schiano Moriello, A; Nalli, M; Ortar, G; De Petrocellis, L Bioorg Med Chem Lett 26: 1401-5 (2016)
- Maarisit, W; Yamazaki, H; Kanno, SI; Tomizawa, A; Rotinsulu, H; Wewengkang, DS; Sumilat, DA; Ukai, K; Kapojos, MM; Namikoshi, M Bioorg Med Chem Lett 27: 999-1002 (2017)
- Bressi, JC; Jennings, AJ; Skene, R; Wu, Y; Melkus, R; De Jong, R; O'Connell, S; Grimshaw, CE; Navre, M; Gangloff, AR Bioorg Med Chem Lett 20: 3142-5 (2010)
- Fernández-Bachiller, MI; Hwang, S; Schembri, ME; Lindemann, P; Guberman, M; Herziger, S; Specker, E; Matter, H; Will, DW; Czech, J; Wagner, M; Bauer, A; Schreuder, H; Ritter, K; Urmann, M; Wehner, V; Sun, H; Nazaré, M J Med Chem 65: 13013-13028 (2022)
- Verdugo, DE; Cancilla, MT; Ge, X; Gray, NS; Chang, YT; Schultz, PG; Negishi, M; Leary, JA; Bertozzi, CR J Med Chem 44: 2683-6 (2001)
- Micheli, F; Cavanni, P; Andreotti, D; Arban, R; Benedetti, R; Bertani, B; Bettati, M; Bettelini, L; Bonanomi, G; Braggio, S; Carletti, R; Checchia, A; Corsi, M; Fazzolari, E; Fontana, S; Marchioro, C; Merlo-Pich, E; Negri, M; Oliosi, B; Ratti, E; Read, KD; Roscic, M; Sartori, I; Spada, S; Tedesco, G; Tarsi, L; Terreni, S; Visentini, F; Zocchi, A; Zonzini, L; Di Fabio, R J Med Chem 53: 4989-5001 (2010)
- Brasca, MG; Gnocchi, P; Nesi, M; Amboldi, N; Avanzi, N; Bertrand, J; Bindi, S; Canevari, G; Casero, D; Ciomei, M; Colombo, N; Cribioli, S; Fachin, G; Felder, ER; Galvani, A; Isacchi, A; Motto, I; Panzeri, A; Donati, D Bioorg Med Chem 23: 2387-407 (2015)
- Cirillo, PF; Hickey, ER; Moss, N; Breitfelder, S; Betageri, R; Fadra, T; Gaenzler, F; Gilmore, T; Goldberg, DR; Kamhi, V; Kirrane, T; Kroe, RR; Madwed, J; Moriak, M; Netherton, M; Pargellis, CA; Patel, UR; Qian, KC; Sharma, R; Sun, S; Swinamer, A; Torcellini, C; Takahashi, H; Tsang, M; Xiong, Z Bioorg Med Chem Lett 19: 2386-91 (2009)
- Knust, H; Nettekoven, M; Ratni, H; Vifian, W US Patent US8618303 (2013)
- Hopkins, BT; Ma, B; Prince, R; Marx, I; Schulz, J; Nevalainen, M; Dechantsreiter, M US Patent US10899753 (2021)
- Taguchi, M; Sugimoto, K; Goda, K; Akama, T; Yamamoto, K; Suzuki, T; Tomishima, Y; Nishiguchi, M; Arai, K; Takahashi, K; Kobori, T Bioorg Med Chem Lett 13: 1963-6 (2003)
- Le Manach, C; Paquet, T; Brunschwig, C; Njoroge, M; Han, Z; Gonzŕlez Cabrera, D; Bashyam, S; Dhinakaran, R; Taylor, D; Reader, J; Botha, M; Churchyard, A; Lauterbach, S; Coetzer, TL; Birkholtz, LM; Meister, S; Winzeler, EA; Waterson, D; Witty, MJ; Wittlin, S; Jiménez-Díaz, MB; Santos Martínez, M; Ferrer, S; Angulo-Barturen, I; Street, LJ; Chibale, K J Med Chem 58: 8713-22 (2015)
- Kotoku, M; Maeba, T; Fujioka, S; Yokota, M; Seki, N; Ito, K; Suwa, Y; Ikenogami, T; Hirata, K; Hase, Y; Katsuda, Y; Miyagawa, N; Arita, K; Asahina, K; Noguchi, M; Nomura, A; Doi, S; Adachi, T; Crowe, P; Tao, H; Thacher, S; Hashimoto, H; Suzuki, T; Shiozaki, M J Med Chem 62: 2837-2842 (2019)
- Heightman, TD; Berdini, V; Braithwaite, H; Buck, IM; Cassidy, M; Castro, J; Courtin, A; Day, JEH; East, C; Fazal, L; Graham, B; Griffiths-Jones, CM; Lyons, JF; Martins, V; Muench, S; Munck, JM; Norton, D; O'Reilly, M; Palmer, N; Pathuri, P; Reader, M; Rees, DC; Rich, SJ; Richardson, C; Saini, H; Thompson, NT; Wallis, NG; Walton, H; Wilsher, NE; Woolford, AJ; Cooke, M; Cousin, D; Onions, S; Shannon, J; Watts, J; Murray, CW J Med Chem 61: 4978-4992 (2018)
- Kiyama, R; Honma, T; Hayashi, K; Ogawa, M; Hara, M; Fujimoto, M; Fujishita, T J Med Chem 38: 2728-41 (1995)
- Oh, M; Im, I; Lee, YJ; Kim, YH; Yoon, JH; Park, HG; Higashiyama, S; Kim, YC; Park, WJ Bioorg Med Chem Lett 14: 6071-4 (2004)
- Ohashi, M; Oyama, T; Nakagome, I; Satoh, M; Nishio, Y; Nobusada, H; Hirono, S; Morikawa, K; Hashimoto, Y; Miyachi, H J Med Chem 54: 331-41 (2011)
- Ishida, J; Yamamoto, H; Kido, Y; Kamijo, K; Murano, K; Miyake, H; Ohkubo, M; Kinoshita, T; Warizaya, M; Iwashita, A; Mihara, K; Matsuoka, N; Hattori, K Bioorg Med Chem 14: 1378-90 (2006)
- Ebiike, H; Taka, N; Matsushita, M; Ohmori, M; Takami, K; Hyohdoh, I; Kohchi, M; Hayase, T; Nishii, H; Morikami, K; Nakanishi, Y; Akiyama, N; Shindoh, H; Ishii, N; Isobe, T; Matsuoka, H J Med Chem 59: 10586-10600 (2016)
- Jacobson, KA; Ohno, M; Duong, HT; Kim, SK; Tchilibon, S; Cesnek, M; Holý, A; Gao, ZG Chem Biol 12: 237-47 (2005)
- Hayakawa, M; Kaizawa, H; Kawaguchi, K; Ishikawa, N; Koizumi, T; Ohishi, T; Yamano, M; Okada, M; Ohta, M; Tsukamoto, S; Raynaud, FI; Waterfield, MD; Parker, P; Workman, P Bioorg Med Chem 15: 403-12 (2007)
- Tsuri, T; Honma, T; Hiramatsu, Y; Okada, T; Hashizume, H; Mitsumori, S; Inagaki, M; Arimura, A; Yasui, K; Asanuma, F; Kishino, J; Ohtani, M J Med Chem 40: 3504-7 (1997)
- Hayakawa, M; Kawaguchi, K; Kaizawa, H; Koizumi, T; Ohishi, T; Yamano, M; Okada, M; Ohta, M; Tsukamoto, S; Raynaud, FI; Parker, P; Workman, P; Waterfield, MD Bioorg Med Chem 15: 5837-44 (2007)
- Moreau, P; Anizon, F; Sancelme, M; Prudhomme, M; Bailly, C; Carrasco, C; Ollier, M; Sevčre, D; Riou, JF; Fabbro, D; Meyer, T; Aubertin, AM J Med Chem 41: 1631-40 (1998)
- Pierre, F; Chua, PC; O'Brien, SE; Siddiqui-Jain, A; Bourbon, P; Haddach, M; Michaux, J; Nagasawa, J; Schwaebe, MK; Stefan, E; Vialettes, A; Whitten, JP; Chen, TK; Darjania, L; Stansfield, R; Anderes, K; Bliesath, J; Drygin, D; Ho, C; Omori, M; Proffitt, C; Streiner, N; Trent, K; Rice, WG; Ryckman, DM J Med Chem 54: 635-54 (2011)
- Kubota, K; Kurebayashi, H; Miyachi, H; Tobe, M; Onishi, M; Isobe, Y Bioorg Med Chem Lett 19: 2766-71 (2009)
- Ono, M; Yoshida, N; Ishibashi, K; Haratake, M; Arano, Y; Mori, H; Nakayama, M J Med Chem 48: 7253-60 (2005)
- Manetti, F; Santucci, A; Locatelli, GA; Maga, G; Spreafico, A; Serchi, T; Orlandini, M; Bernardini, G; Caradonna, NP; Spallarossa, A; Brullo, C; Schenone, S; Bruno, O; Ranise, A; Bondavalli, F; Hoffmann, O; Bologna, M; Angelucci, A; Botta, M J Med Chem 50: 5579-88 (2007)
- Tsou, HR; Otteng, M; Tran, T; Floyd, MB; Reich, M; Birnberg, G; Kutterer, K; Ayral-Kaloustian, S; Ravi, M; Nilakantan, R; Grillo, M; McGinnis, JP; Rabindran, SK J Med Chem 51: 3507-25 (2008)
- Gauthier, JY; Black, WC; Courchesne, I; Cromlish, W; Desmarais, S; Houle, R; Lamontagne, S; Li, CS; Massé, F; McKay, DJ; Ouellet, M; Robichaud, J; Truchon, JF; Truong, VL; Wang, Q; Percival, MD Bioorg Med Chem Lett 17: 4929-33 (2007)
- Sanchez-Martinez, C; Shih, C; Faul, MM; Zhu, G; Paal, M; Somoza, C; Li, T; Kumrich, CA; Winneroski, LL; Xun, Z; Brooks, HB; Patel, BK; Schultz, RM; DeHahn, TB; Spencer, CD; Watkins, SA; Considine, E; Dempsey, JA; Ogg, CA; Campbell, RM; Anderson, BA; Wagner, J Bioorg Med Chem Lett 13: 3835-9 (2003)
- Liessi, N; Cichero, E; Pesce, E; Arkel, M; Salis, A; Tomati, V; Paccagnella, M; Damonte, G; Tasso, B; Galietta, LJV; Pedemonte, N; Fossa, P; Millo, E Eur J Med Chem 144: 179-200 (2018)
- Pismataro, MC; Astolfi, A; Barreca, ML; Pacetti, M; Schenone, S; Bandiera, T; Carbone, A; Massari, S J Med Chem 66: 6498-6522 (2023)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Liu, Y; Richardson, J; Tran, T; Al-Muhtasib, N; Xie, T; Yenugonda, VM; Sexton, HG; Rezvani, AH; Levin, ED; Sahibzada, N; Kellar, KJ; Brown, ML; Xiao, Y; Paige, M J Med Chem 56: 3000-11 (2013)
- Li, YL; Shi, E; Burns, D; Li, Y; Covington, MB; Pan, M; Scherle, P; Friedman, S; Metcalf, B; Yao, W Bioorg Med Chem Lett 19: 5037-42 (2009)
- Razavi, H; Riether, D; Harcken, C; Bentzien, J; Dinallo, RM; Souza, D; Nelson, RM; Kukulka, A; Fadra-Khan, TN; Pack, EJ; Zuvela-Jelaska, L; Pelletier, J; Panzenbeck, M; Torcellini, CA; Proudfoot, JR; Nabozny, GH; Thomson, DS Bioorg Med Chem Lett 24: 1934-40 (2014)
- Cappelli, A; Manini, M; Paolino, M; Gallelli, A; Anzini, M; Mennuni, L; Del Cadia, M; De Rienzo, F; Menziani, MC; Vomero, S ACS Med Chem Lett 2: 571-576 (2011)
- Piemontese, L; Fracchiolla, G; Carrieri, A; Parente, M; Laghezza, A; Carbonara, G; Sblano, S; Tauro, M; Gilardi, F; Tortorella, P; Lavecchia, A; Crestani, M; Desvergne, B; Loiodice, F Eur J Med Chem 90: 583-94 (2015)
- Cui, JJ; McTigue, M; Nambu, M; Tran-Dubé, M; Pairish, M; Shen, H; Jia, L; Cheng, H; Hoffman, J; Le, P; Jalaie, M; Goetz, GH; Ryan, K; Grodsky, N; Deng, YL; Parker, M; Timofeevski, S; Murray, BW; Yamazaki, S; Aguirre, S; Li, Q; Zou, H; Christensen, J J Med Chem 55: 8091-109 (2012)
- Rossi, C; Porcelloni, M; D'Andrea, P; Fincham, CI; Ettorre, A; Mauro, S; Squarcia, A; Bigioni, M; Parlani, M; Nardelli, F; Binaschi, M; Maggi, CA; Fattori, D Bioorg Med Chem Lett 21: 2305-8 (2011)
- Sohy, D; Parmentier, M; Springael, JY J Biol Chem 282: 30062-9 (2007)
- Vidadala, RS; Rivas, KL; Ojo, KK; Hulverson, MA; Zambriski, JA; Bruzual, I; Schultz, TL; Huang, W; Zhang, Z; Scheele, S; DeRocher, AE; Choi, R; Barrett, LK; Siddaramaiah, LK; Hol, WG; Fan, E; Merritt, EA; Parsons, M; Freiberg, G; Marsh, K; Kempf, DJ; Carruthers, VB; Isoherranen, N; Doggett, JS; Van Voorhis, WC; Maly, DJ J Med Chem 59: 6531-46 (2016)
- Chu, M; Mierzwa, R; He, L; King, A; Patel, M; Pichardo, J; Hart, A; Butkiewicz, N; Puar, MS Bioorg Med Chem Lett 9: 1949-52 (1999)
- Canale, V; Guzik, P; Kurczab, R; Verdie, P; Satala, G; Kubica, B; Pawlowski, M; Martinez, J; Subra, G; Bojarski, AJ; Zajdel, P Eur J Med Chem 78: 10-22 (2014)
- Cee, VJ; Schenkel, LB; Hodous, BL; Deak, HL; Nguyen, HN; Olivieri, PR; Romero, K; Bak, A; Be, X; Bellon, S; Bush, TL; Cheng, AC; Chung, G; Coats, S; Eden, PM; Hanestad, K; Gallant, PL; Gu, Y; Huang, X; Kendall, RL; Lin, MH; Morrison, MJ; Patel, VF; Radinsky, R; Rose, PE; Ross, S; Sun, JR; Tang, J; Zhao, H; Payton, M; Geuns-Meyer, SD J Med Chem 53: 6368-77 (2010)
- Vazquez, J; De, SK; Chen, LH; Riel-Mehan, M; Emdadi, A; Cellitti, J; Stebbins, JL; Rega, MF; Pellecchia, M J Med Chem 51: 3460-5 (2008)
- Flohr, A; Hutter, R; Mueller, B; Bohnert, C; Pellisson, M; Schaffhauser, H Bioorg Med Chem Lett 27: 5415-5419 (2017)
- Jones, LH; Allan, G; Barba, O; Burt, C; Corbau, R; Dupont, T; Knöchel, T; Irving, S; Middleton, DS; Mowbray, CE; Perros, M; Ringrose, H; Swain, NA; Webster, R; Westby, M; Phillips, C J Med Chem 52: 1219-23 (2009)
- Helmboldt, A; Petitou, M; Mallet, J; Herault, J; Lormeau, J; Driguez, PA; Herbert, J; Sinay, P Bioorg Med Chem Lett 7: 1507-1510 (1997)
- Malosh, C; Turlington, M; Bridges, TM; Rook, JM; Noetzel, MJ; Vinson, PN; Steckler, T; Lavreysen, H; Mackie, C; Bartolomé-Nebreda, JM; Conde-Ceide, S; Martínez-Viturro, CM; Piedrafita, M; Sánchez-Casado, MR; Macdonald, GJ; Daniels, JS; Jones, CK; Niswender, CM; Conn, PJ; Lindsley, CW; Stauffer, SR Bioorg Med Chem Lett 25: 5115-20 (2015)
- Angeli, A; Pinteala, M; Maier, SS; Toti, A; Di Cesare Mannelli, L; Ghelardini, C; Selleri, S; Carta, F; Supuran, CT Bioorg Med Chem Lett 45: (2021)
- Prezzavento, O; Campisi, A; Parenti, C; Ronsisvalle, S; Aricò, G; Arena, E; Pistolozzi, M; Scoto, GM; Bertucci, C; Vanella, A; Ronsisvalle, G J Med Chem 53: 5881-5 (2010)
- Proudfoot, JR; Betageri, R; Cardozo, M; Gilmore, TA; Glynn, S; Hickey, ER; Jakes, S; Kabcenell, A; Kirrane, TM; Tibolla, AK; Lukas, S; Patel, UR; Sharma, R; Yazdanian, M; Moss, N; Beaulieu, PL; Cameron, DR; Ferland, JM; Gauthier, J; Gillard, J; Gorys, V; Poirier, M; Rancourt, J; Wernic, D; Llinas-Brunet, M J Med Chem 44: 2421-31 (2001)
- Pace, P; Di Francesco, ME; Gardelli, C; Harper, S; Muraglia, E; Nizi, E; Orvieto, F; Petrocchi, A; Poma, M; Rowley, M; Scarpelli, R; Laufer, R; Gonzalez Paz, O; Monteagudo, E; Bonelli, F; Hazuda, D; Stillmock, KA; Summa, V J Med Chem 50: 2225-39 (2007)
- Gilbert, J; Fuentes, M; Ojasoo, T; Doré, JC; Pons, M J Med Chem 40: 1104-11 (1997)
- Rossi, C; Porcelloni, M; D'Andrea, P; Fincham, CI; Ettorre, A; Mauro, S; Squarcia, A; Bigioni, M; Parlani, M; Nardelli, F; Binaschi, M; Maggi, CA; Fattori, D Bioorg Med Chem Lett 21: 2305-8 (2011)
- Buchler, I; Akuma, D; Au, V; Carr, G; de León, P; DePasquale, M; Ernst, G; Huang, Y; Kimos, M; Kolobova, A; Poslusney, M; Wei, H; Swinnen, D; Montel, F; Moureau, F; Jigorel, E; Schulze, MED; Wood, M; Barrow, JC J Med Chem 61: 9647-9665 (2018)
- He, L; Seitz, SP; Trainor, GL; Tortolani, D; Vaccaro, W; Poss, M; Tarby, CM; Tokarski, JS; Penhallow, B; Hung, CY; Attar, R; Lin, TA Bioorg Med Chem Lett 22: 5995-8 (2012)
- Hansen, JD; Correa, M; Alexander, M; Nagy, M; Huang, D; Sapienza, J; Lu, G; LeBrun, LA; Cathers, BE; Zhang, W; Tang, Y; Ammirante, M; Narla, RK; Piccotti, JR; Pourdehnad, M; Lopez-Girona, A J Med Chem 64: 1835-1843 (2021)
- Moorjani, M; Zhang, X; Chen, Y; Lin, E; Rueter, JK; Gross, RS; Lanier, MC; Tellew, JE; Williams, JP; Lechner, SM; Malany, S; Santos, M; Ekhlassi, P; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Saunders, J; Slee, DH Bioorg Med Chem Lett 18: 1269-73 (2008)
- Pearlstein, RA; Vaz, RJ; Kang, J; Chen, XL; Preobrazhenskaya, M; Shchekotikhin, AE; Korolev, AM; Lysenkova, LN; Miroshnikova, OV; Hendrix, J; Rampe, D Bioorg Med Chem Lett 13: 1829-35 (2003)
- Castelli, R; Taranto, S; Furiassi, L; Bozza, N; Marseglia, G; Ferlenghi, F; Rivara, S; Retini, M; Bedini, A; Spadoni, G; Matarazzo, S; Ronca, R; Presta, M; Mor, M; Giacomini, A Eur J Med Chem 221: (2021)
- Pretze, M; Pallavi, P; Roscher, M; Klotz, S; Caballero, J; Binzen, U; Greffrath, W; Treede, RD; Harmsen, MC; Hafner, M; Yard, B; Wängler, C; Wängler, B J Med Chem 59: 9855-9865 (2016)
- Whittaker, M; Thompson, TM; Spavold, ZM; Price, M; Miller, A; Galloway, W; Fraser, F; Floyd, CD; Drummond, AH; Davidson, AH; Bowles, SA; Bebbington, DS Bioorg Med Chem Lett 3: 1493-1498 (1993)
- Hill, D; Horwell, D; Hunter, J; Kneen, C; Pritchard, M; Suman-Chauhan, N Bioorg Med Chem Lett 3: 885-888 (1993)
- Moreau, P; Anizon, F; Sancelme, M; Prudhomme, M; Bailly, C; Carrasco, C; Ollier, M; Sevčre, D; Riou, JF; Fabbro, D; Meyer, T; Aubertin, AM J Med Chem 41: 1631-40 (1998)
- Qi, M; Zhong, H; Cheng, Z; Chen, S; Xiao, H; Shang, J; Chen, L; Sun, J J Med Chem 66: 9184-9200 (2023)
- Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bioorg Med Chem Lett 17: 1865-70 (2007)
- Li, Y; Ye, T; Xu, L; Dong, Y; Luo, Y; Wang, C; Han, Y; Chen, K; Qin, M; Liu, Y; Zhao, Y Eur J Med Chem 181: (2019)
- Quibell, M; Watts, JP; Flinn, NS US Patent US8552202 (2013)
- Piticchio, SG; Martínez-Cartró, M; Scaffidi, S; Rachman, M; Rodriguez-Arevalo, S; Sanchez-Arfelis, A; Escolano, C; Picaud, S; Krojer, T; Filippakopoulos, P; von Delft, F; Galdeano, C; Barril, X J Med Chem 64: 17887-17900 (2021)
- Crespan, E; Radi, M; Zanoli, S; Schenone, S; Botta, M; Maga, G Bioorg Med Chem 18: 3999-4008 (2010)
- Rockwell, AL; Rafalski, M; Pitts, WJ; Batt, DG; Petraitis, JJ; DeGrado, WF; Mousa, S; Jadhav, PK Bioorg Med Chem Lett 9: 937-42 (1999)
- Belayet, JB; Beamish, S; Rahaman, M; Alanani, S; Virdi, RS; Frick, DN; Rahman, AFMT; Ulicki, JS; Biswas, S; Arnold, LA; Roni, MSR; Cheng, EY; Steeber, DA; Frick, KM; Hossain, MM J Med Chem 65: 3388-3403 (2022)
- Korhonen, LE; Rahnasto, M; Mähönen, NJ; Wittekindt, C; Poso, A; Juvonen, RO; Raunio, H J Med Chem 48: 3808-15 (2005)
- Rueda, DC; Schöffmann, A; De Mieri, M; Raith, M; Jähne, EA; Hering, S; Hamburger, M Bioorg Med Chem 22: 1276-84 (2014)
- Rajabi, M; Mansell, D; Freeman, S; Bryce, RA Eur J Med Chem 46: 1165-71 (2011)
- Marsault, E; Hoveyda, HR; Peterson, ML; Saint-Louis, C; Landry, A; Vézina, M; Ouellet, L; Wang, Z; Ramaseshan, M; Beaubien, S; Benakli, K; Beauchemin, S; Déziel, R; Peeters, T; Fraser, GL J Med Chem 49: 7190-7 (2006)
- Long, DD; Armstrong, SR; Beattie, DT; Campbell, CB; Church, TJ; Colson, PJ; Dalziel, SM; Jacobsen, JR; Jiang, L; Obedencio, GP; Rapta, M; Saito, D; Stergiades, I; Tsuruda, PR; Van Dyke, PM; Vickery, RG ACS Med Chem Lett 10: 1641-1647 (2019)
- Tsou, HR; Otteng, M; Tran, T; Floyd, MB; Reich, M; Birnberg, G; Kutterer, K; Ayral-Kaloustian, S; Ravi, M; Nilakantan, R; Grillo, M; McGinnis, JP; Rabindran, SK J Med Chem 51: 3507-25 (2008)
- Heightman, TD; Berdini, V; Braithwaite, H; Buck, IM; Cassidy, M; Castro, J; Courtin, A; Day, JEH; East, C; Fazal, L; Graham, B; Griffiths-Jones, CM; Lyons, JF; Martins, V; Muench, S; Munck, JM; Norton, D; O'Reilly, M; Palmer, N; Pathuri, P; Reader, M; Rees, DC; Rich, SJ; Richardson, C; Saini, H; Thompson, NT; Wallis, NG; Walton, H; Wilsher, NE; Woolford, AJ; Cooke, M; Cousin, D; Onions, S; Shannon, J; Watts, J; Murray, CW J Med Chem 61: 4978-4992 (2018)
- Tsou, HR; Otteng, M; Tran, T; Floyd, MB; Reich, M; Birnberg, G; Kutterer, K; Ayral-Kaloustian, S; Ravi, M; Nilakantan, R; Grillo, M; McGinnis, JP; Rabindran, SK J Med Chem 51: 3507-25 (2008)
- Shen, L; Zhang, Y; Wang, A; Sieber-McMaster, E; Chen, X; Pelton, P; Xu, JZ; Yang, M; Zhu, P; Zhou, L; Reuman, M; Hu, Z; Russell, R; Gibbs, AC; Ross, H; Demarest, K; Murray, WV; Kuo, GH Bioorg Med Chem 16: 3321-41 (2008)
- Maerki, HP; Hornsperger, B; Mohr, P; Reutlinger, M; Iacone, R US Patent US11059858 (2021)
- Bharathan, IT; Blackburn, C; Ciavarri, JP; Chouitar, J; Cullis, CA; D Amore, N; Fleming, PE; Gigstad, KM; Gipson, KE; Girard, M; Hu, Y; Lee, J; Li, G; Rezaei, M; Sintchak, MD; Soucy, F; Stroud, SG; Vos, TJ; Xu, H; Ye, Y US Patent US10202373 (2019)
- Taha, M; Ismail, NH; Imran, S; Wadood, A; Rahim, F; Riaz, M Bioorg Med Chem 23: 7211-8 (2015)
- Fantini, M; Rivara, M; Zuliani, V; Kalmar, CL; Vacondio, F; Silva, C; Baheti, AR; Singh, N; Merrick, EC; Katari, RS; Cocconcelli, G; Ghiron, C; Patel, MK Bioorg Med Chem 17: 3642-8 (2009)
- Kozikowski, AP; Roberti, M; Johnson, KM; Bergmann, JS; Ball, RG Bioorg Med Chem Lett 3: 1327-1332 (1993)
- Baxter, A; Bent, J; Bowers, K; Braddock, M; Brough, S; Fagura, M; Lawson, M; McInally, T; Mortimore, M; Robertson, M; Weaver, R; Webborn, P Bioorg Med Chem Lett 13: 4047-50 (2003)
- Pretze, M; Pallavi, P; Roscher, M; Klotz, S; Caballero, J; Binzen, U; Greffrath, W; Treede, RD; Harmsen, MC; Hafner, M; Yard, B; Wängler, C; Wängler, B J Med Chem 59: 9855-9865 (2016)
- Micheli, F; Cavanni, P; Andreotti, D; Arban, R; Benedetti, R; Bertani, B; Bettati, M; Bettelini, L; Bonanomi, G; Braggio, S; Carletti, R; Checchia, A; Corsi, M; Fazzolari, E; Fontana, S; Marchioro, C; Merlo-Pich, E; Negri, M; Oliosi, B; Ratti, E; Read, KD; Roscic, M; Sartori, I; Spada, S; Tedesco, G; Tarsi, L; Terreni, S; Visentini, F; Zocchi, A; Zonzini, L; Di Fabio, R J Med Chem 53: 4989-5001 (2010)
- Hale, JJ; Neway, W; Mills, SG; Hajdu, R; Ann Keohane, C; Rosenbach, M; Milligan, J; Shei, GJ; Chrebet, G; Bergstrom, J; Card, D; Koo, GC; Koprak, SL; Jackson, JJ; Rosen, H; Mandala, S Bioorg Med Chem Lett 14: 3351-5 (2004)
- Wu, T; Nagle, A; Kuhen, K; Gagaring, K; Borboa, R; Francek, C; Chen, Z; Plouffe, D; Goh, A; Lakshminarayana, SB; Wu, J; Ang, HQ; Zeng, P; Kang, ML; Tan, W; Tan, M; Ye, N; Lin, X; Caldwell, C; Ek, J; Skolnik, S; Liu, F; Wang, J; Chang, J; Li, C; Hollenbeck, T; Tuntland, T; Isbell, J; Fischli, C; Brun, R; Rottmann, M; Dartois, V; Keller, T; Diagana, T; Winzeler, E; Glynne, R; Tully, DC; Chatterjee, AK J Med Chem 54: 5116-30 (2011)
- Beneker, CM; Rovoli, M; Kontopidis, G; Röring, M; Galda, S; Braun, S; Brummer, T; McInnes, C J Med Chem 62: 3886-3897 (2019)
- Scarpelli, R; Di Marco, A; Ferrigno, F; Laufer, R; Marcucci, I; Muraglia, E; Ontoria, JM; Rowley, M; Serafini, S; Steinkühler, C; Jones, P Bioorg Med Chem Lett 18: 6078-82 (2008)
- Guerlet, G; Spangenberg, T; Mann, A; Faure, H; Ruat, M Bioorg Med Chem Lett 21: 3608-12 (2011)
- Liu, J; He, S; Jian, T; Dobbelaar, PH; Sebhat, IK; Lin, LS; Goodman, A; Guo, C; Guzzo, PR; Hadden, M; Henderson, AJ; Pattamana, K; Ruenz, M; Sargent, BJ; Swenson, B; Yet, L; Tamvakopoulos, C; Peng, Q; Pan, J; Kan, Y; Palyha, O; Kelly, TM; Guan, XM; Howard, AD; Marsh, DJ; Metzger, JM; Reitman, ML; Wyvratt, MJ; Nargund, RP Bioorg Med Chem Lett 20: 2074-7 (2010)
- Chiellini, G; Nesi, G; Sestito, S; Chiarugi, S; Runfola, M; Espinoza, S; Sabatini, M; Bellusci, L; Laurino, A; Cichero, E; Gainetdinov, RR; Fossa, P; Raimondi, L; Zucchi, R; Rapposelli, S J Med Chem 59: 9825-9836 (2016)
- Parodi, A; Righetti, G; Pesce, E; Salis, A; Tasso, B; Urbinati, C; Tomati, V; Damonte, G; Rusnati, M; Pedemonte, N; Cichero, E; Millo, E Eur J Med Chem 208: (2020)
- Beneker, CM; Rovoli, M; Kontopidis, G; Röring, M; Galda, S; Braun, S; Brummer, T; McInnes, C J Med Chem 62: 3886-3897 (2019)
- Kong, Y; Grembecka, J; Edler, MC; Hamel, E; Mooberry, SL; Sabat, M; Rieger, J; Brown, ML Chem Biol 12: 1007-14 (2005)
- Chiellini, G; Nesi, G; Sestito, S; Chiarugi, S; Runfola, M; Espinoza, S; Sabatini, M; Bellusci, L; Laurino, A; Cichero, E; Gainetdinov, RR; Fossa, P; Raimondi, L; Zucchi, R; Rapposelli, S J Med Chem 59: 9825-9836 (2016)
- Peukert, S; Sun, Y; Zhang, R; Hurley, B; Sabio, M; Shen, X; Gray, C; Dzink-Fox, J; Tao, J; Cebula, R; Wattanasin, S Bioorg Med Chem Lett 18: 1840-4 (2008)
- Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Eur J Med Chem 64: 488-97 (2013)
- Yoshikawa, M; Saitoh, M; Kato, T; Nakayama, Y; Seki, T; Nakagawa, Y; Tominari, Y; Seto, M; Sasaki, Y; Okaniwa, M; Oda, T; Shibuya, A; Hidaka, K; Shiokawa, Z; Murata, S; Okabe, A; Nakada, Y; Mochizuki, M; Freeze, BS; Tawaraishi, T; Wada, Y; Greenspan, PD US Patent US11666594 (2023)
- Aoki, T; Hyohdoh, I; Furuichi, N; Ozawa, S; Watanabe, F; Matsushita, M; Sakaitani, M; Morikami, K; Takanashi, K; Harada, N; Tomii, Y; Shiraki, K; Furumoto, K; Tabo, M; Yoshinari, K; Ori, K; Aoki, Y; Shimma, N; Iikura, H ACS Med Chem Lett 5: 309-14 (2014)
- Salah, M; Tahoun, M; Rudzitis-Auth, J; Stotz, L; van Koppen, CJ; Laschke, MW; Abdelsamie, AS; Frotscher, M J Med Chem 66: 8975-8992 (2023)
- Filipuzzi, I; Thomas, JR; Pries, V; Estoppey, D; Salcius, M; Studer, C; Schirle, M; Hoepfner, D ACS Chem Biol 12: 2264-2269 (2017)
- Garner, AL; Gloeckner, C; Tricoche, N; Zakhari, JS; Samje, M; Cho-Ngwa, F; Lustigman, S; Janda, KD J Med Chem 54: 3963-72 (2011)
- Moreau, P; Anizon, F; Sancelme, M; Prudhomme, M; Bailly, C; Carrasco, C; Ollier, M; Sevčre, D; Riou, JF; Fabbro, D; Meyer, T; Aubertin, AM J Med Chem 41: 1631-40 (1998)
- Rak, M; Tesch, R; Berger, LM; Shevchenko, E; Raab, M; Tjaden, A; Zhubi, R; Balourdas, DI; Joerger, AC; Poso, A; Krämer, A; Elson, L; Lu?i?, A; Kronenberger, T; Hanke, T; Strebhardt, K; Sanhaji, M; Knapp, S Eur J Med Chem 254: (2023)
- Manca, I; Mastinu, A; Olimpieri, F; Falzoi, M; Sani, M; Ruiu, S; Loriga, G; Volonterio, A; Tambaro, S; Bottazzi, ME; Zanda, M; Pinna, GA; Lazzari, P Eur J Med Chem 62: 256-69 (2013)
- Moorjani, M; Zhang, X; Chen, Y; Lin, E; Rueter, JK; Gross, RS; Lanier, MC; Tellew, JE; Williams, JP; Lechner, SM; Malany, S; Santos, M; Ekhlassi, P; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Saunders, J; Slee, DH Bioorg Med Chem Lett 18: 1269-73 (2008)
- Saquib, M; Ansari, MI; Johnson, CR; Khatoon, S; Kamil Hussain, M; Coop, A Eur J Med Chem 182: (2019)
- Skerlj, R; Bridger, G; Zhou, Y; Bourque, E; McEachern, E; Langille, J; Harwig, C; Veale, D; Yang, W; Li, T; Zhu, Y; Bey, M; Baird, I; Sartori, M; Metz, M; Mosi, R; Nelson, K; Bodart, V; Wong, R; Fricker, S; Mac Farland, R; Huskens, D; Schols, D Bioorg Med Chem Lett 21: 6950-4 (2011)
- Harada, K; Mizukami, J; Watanabe, T; Mori, G; Ubukata, M; Suwa, K; Fukuda, S; Negoro, T; Sato, M; Inaba, T Bioorg Med Chem Lett 29: 2100-2106 (2019)
- Ohashi, M; Oyama, T; Nakagome, I; Satoh, M; Nishio, Y; Nobusada, H; Hirono, S; Morikawa, K; Hashimoto, Y; Miyachi, H J Med Chem 54: 331-41 (2011)
- Asami, T; Kawahata, W; Sawa, M Bioorg Med Chem Lett 25: 2033-6 (2015)
- Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS Proc Natl Acad Sci U S A 104: 8520-5 (2007)
- Shen, Y; Li, F; Szewczyk, MM; Halabelian, L; Chau, I; Eram, MS; Dela Seńa, C; Park, KS; Meng, F; Chen, H; Zeng, H; Dong, A; Wu, H; Trush, VV; McLeod, D; Zepeda-Velázquez, CA; Campbell, RM; Mader, MM; Watson, BM; Schapira, M; Arrowsmith, CH; Al-Awar, R; Barsyte-Lovejoy, D; Kaniskan, HÜ; Brown, PJ; Vedadi, M; Jin, J J Med Chem 64: 3697-3706 (2021)
- Klein, T; Abgottspon, D; Wittwer, M; Rabbani, S; Herold, J; Jiang, X; Kleeb, S; Lüthi, C; Scharenberg, M; Bezençon, J; Gubler, E; Pang, L; Smiesko, M; Cutting, B; Schwardt, O; Ernst, B J Med Chem 53: 8627-41 (2010)
- Sundén, H; Schäfer, A; Scheepstra, M; Leysen, S; Malo, M; Ma, JN; Burstein, ES; Ottmann, C; Brunsveld, L; Olsson, R J Med Chem 59: 1232-8 (2016)
- Vucicevic, J; Srdic-Rajic, T; Pieroni, M; Laurila, JM; Perovic, V; Tassini, S; Azzali, E; Costantino, G; Glisic, S; Agbaba, D; Scheinin, M; Nikolic, K; Radi, M; Veljkovic, N Bioorg Med Chem 24: 3174-83 (2016)
- Bolli, MH; Abele, S; Binkert, C; Bravo, R; Buchmann, S; Bur, D; Gatfield, J; Hess, P; Kohl, C; Mangold, C; Mathys, B; Menyhart, K; Müller, C; Nayler, O; Scherz, M; Schmidt, G; Sippel, V; Steiner, B; Strasser, D; Treiber, A; Weller, T J Med Chem 53: 4198-211 (2010)
- Winter-Holt, JJ; Bardelle, C; Chiarparin, E; Dale, IL; Davey, PRJ; Davies, NL; Denz, C; Fillery, SM; Guérot, CM; Han, F; Hughes, SJ; Kulkarni, M; Liu, Z; Milbradt, A; Moss, TA; Niu, H; Patel, J; Rabow, AA; Schimpl, M; Shi, J; Sun, D; Yang, D; Guichard, S J Med Chem 65: 3306-3331 (2022)
- Filipuzzi, I; Thomas, JR; Pries, V; Estoppey, D; Salcius, M; Studer, C; Schirle, M; Hoepfner, D ACS Chem Biol 12: 2264-2269 (2017)
- von Rauch, M; Schlenk, M; Gust, R J Med Chem 47: 915-27 (2004)
- Liu, J; Li, AR; Wang, Y; Johnson, MG; Su, Y; Shen, W; Wang, X; Lively, S; Brown, M; Lai, S; Gonzalez Lopez De Turiso, F; Xu, Q; Van Lengerich, B; Schmitt, M; Fu, Z; Sun, Y; Lawlis, S; Seitz, L; Danao, J; Wait, J; Ye, Q; Tang, HL; Grillo, M; Collins, TL; Sullivan, TJ; Medina, JC ACS Med Chem Lett 2: 326-330 (2011)
- Swahn, BM; Sandell, J; Pyring, D; Bergh, M; Jeppsson, F; Juréus, A; Neelissen, J; Johnström, P; Schou, M; Svensson, S Bioorg Med Chem Lett 22: 4332-7 (2012)
- Chaikuad, A; Diharce, J; Schröder, M; Foucourt, A; Leblond, B; Casagrande, AS; Désiré, L; Bonnet, P; Knapp, S; Besson, T J Med Chem 59: 10315-10321 (2016)
- Sechi, M; Innocenti, A; Pala, N; Rogolino, D; Carcelli, M; Scozzafava, A; Supuran, CT Bioorg Med Chem Lett 22: 5801-6 (2012)
- Michaelis, S; Marais, A; Schrey, AK; Graebner, OY; Schaudt, C; Sefkow, M; Kroll, F; Dreger, M; Glinski, M; Koester, H; Metternich, R; Fischer, JJ J Med Chem 55: 3934-44 (2012)
- Keith, JM; Jones, WM; Pierce, JM; Seierstad, M; Palmer, JA; Webb, M; Karbarz, MJ; Scott, BP; Wilson, SJ; Luo, L; Wennerholm, ML; Chang, L; Brown, SM; Rizzolio, M; Rynberg, R; Chaplan, SR; Breitenbucher, JG Bioorg Med Chem Lett 24: 737-41 (2014)
- Kuntz, KW; Campbell, JE; Seki, M US Patent US10098888 (2018)
- Hosoguchi, K; Maeda, T; Furukawa, J; Shinohara, Y; Hinou, H; Sekiguchi, M; Togame, H; Takemoto, H; Kondo, H; Nishimura, S J Med Chem 53: 5607-19 (2010)
- Taha, M; Ismail, NH; Imran, S; Selvaraj, M; Rahim, A; Ali, M; Siddiqui, S; Rahim, F; Khan, KM Bioorg Med Chem 23: 7394-404 (2015)
- Fidan, I; Salmas, RE; Arslan, M; Sentürk, M; Durdagi, S; Ekinci, D; Sentürk, E; Cosgun, S; Supuran, CT Bioorg Med Chem 23: 7353-8 (2015)
- Jovanovi?, M; Zhukovsky, D; Podolski-Reni?, A; Domra?eva, I; ?alubovskis, R; Sen?anski, M; Gli?i?, S; Sharoyko, V; Tennikova, T; Dar'in, D; Pe?i?, M; Krasavin, M Eur J Med Chem 181: (2019)
- Amori, L; Serpi, M; Marinozzi, M; Costantino, G; Diaz, MG; Hermit, MB; Thomsen, C; Pellicciari, R Bioorg Med Chem Lett 16: 196-9 (2005)
- Yoshikawa, M; Saitoh, M; Kato, T; Nakayama, Y; Seki, T; Nakagawa, Y; Tominari, Y; Seto, M; Sasaki, Y; Okaniwa, M; Oda, T; Shibuya, A; Hidaka, K; Shiokawa, Z; Murata, S; Okabe, A; Nakada, Y; Mochizuki, M; Freeze, BS; Tawaraishi, T; Wada, Y; Greenspan, PD US Patent US11666594 (2023)
- Olivier, A; Sevrin, M; Durant, F; George, P Bioorg Med Chem Lett 7: 2277-2282 (1997)
- Saeed, A; Mahesar, PA; Zaib, S; Khan, MS; Matin, A; Shahid, M; Iqbal, J Eur J Med Chem 78: 43-53 (2014)
- Manz, TD; Sivakumaren, SC; Yasgar, A; Hall, MD; Davis, MI; Seo, HS; Card, JD; Ficarro, SB; Shim, H; Marto, JA; Dhe-Paganon, S; Sasaki, AT; Boxer, MB; Simeonov, A; Cantley, LC; Shen, M; Zhang, T; Ferguson, FM; Gray, NS ACS Med Chem Lett 11: 346-352 (2020)
- Gopalsamy, A; Chopra, R; Lim, K; Ciszewski, G; Shi, M; Curran, KJ; Sukits, SF; Svenson, K; Bard, J; Ellingboe, JW; Agarwal, A; Krishnamurthy, G; Howe, AY; Orlowski, M; Feld, B; O'Connell, J; Mansour, TS J Med Chem 49: 3052-5 (2006)
- Kiyokawa, S; Hirata, Y; Nagaoka, Y; Shibano, M; Taniguchi, M; Yasuda, M; Baba, K; Uesato, S Bioorg Med Chem 18: 3925-33 (2010)
- Nam, SJ; Ko, H; Shin, M; Ham, J; Chin, J; Kim, Y; Kim, H; Shin, K; Choi, H; Kang, H Bioorg Med Chem Lett 16: 5398-402 (2006)
- Wu, MY; Esteban, G; Brogi, S; Shionoya, M; Wang, L; Campiani, G; Unzeta, M; Inokuchi, T; Butini, S; Marco-Contelles, J Eur J Med Chem 121: 864-879 (2016)
- Noji, S; Seki, N; Maeba, T; Sakai, T; Watanabe, E; Maeda, K; Fukushima, K; Noguchi, T; Ogawa, K; Toyonaga, Y; Negoro, T; Kawasaki, H; Shiozaki, M ACS Med Chem Lett 7: 919-923 (2016)
- Choi, K; Siegel, M; Piper, JL; Yuan, L; Cho, E; Strnad, P; Omary, B; Rich, KM; Khosla, C Chem Biol 12: 469-75 (2005)
- Allan, AC; Billinton, A; Brown, SH; Chowdhury, A; Eatherton, AJ; Fieldhouse, C; Giblin, GM; Goldsmith, P; Hall, A; Hurst, DN; Naylor, A; Rawlings, DA; Sime, M; Scoccitti, T; Theobald, PJ Bioorg Med Chem Lett 21: 4343-8 (2011)
- Singer, M; Lopez, M; Bornaghi, LF; Innocenti, A; Vullo, D; Supuran, CT; Poulsen, SA Bioorg Med Chem Lett 19: 2273-6 (2009)
- Zahid, H; Buchholz, CR; Singh, M; Ciccone, MF; Chan, A; Nithianantham, S; Shi, K; Aihara, H; Fischer, M; Schönbrunn, E; Dos Santos, CO; Landry, JW; Pomerantz, WCK J Med Chem 64: 13902-13917 (2021)
- Hu, LY; Ryder, TR; Rafferty, MF; Feng, MR; Lotarski, SM; Rock, DM; Sinz, M; Stoehr, SJ; Taylor, CP; Weber, ML; Bowersox, SS; Miljanich, GP; Millerman, E; Wang, YX; Szoke, BG J Med Chem 42: 4239-49 (1999)
- Weber, C; Sipos, M; Paczal, A; Balint, B; Kun, V; Foloppe, N; Dokurno, P; Massey, AJ; Walmsley, DL; Hubbard, RE; Murray, J; Benwell, K; Edmonds, T; Demarles, D; Bruno, A; Burbridge, M; Cruzalegui, F; Kotschy, A J Med Chem 64: 6745-6764 (2021)
- Juli, C; Sippel, M; Jäger, J; Thiele, A; Weiwad, M; Schweimer, K; Rösch, P; Steinert, M; Sotriffer, CA; Holzgrabe, U J Med Chem 54: 277-83 (2011)
- Skiles, JW; Miao, C; Sorcek, R; Jacober, S; Mui, PW; Chow, G; Weldon, SM; Possanza, G; Skoog, M; Keirns, J J Med Chem 35: 4795-808 (1993)
- Kees, KL; Musser, JH; Chang, J; Skowronek, M; Lewis, AJ J Med Chem 29: 2329-34 (1986)
- Castanedo, GM; Blaquiere, N; Beresini, M; Bravo, B; Brightbill, H; Chen, J; Cui, HF; Eigenbrot, C; Everett, C; Feng, J; Godemann, R; Gogol, E; Hymowitz, S; Johnson, A; Kayagaki, N; Kohli, PB; Knüppel, K; Kraemer, J; Krüger, S; Loke, P; McEwan, P; Montalbetti, C; Roberts, DA; Smith, M; Steinbacher, S; Sujatha-Bhaskar, S; Takahashi, R; Wang, X; Wu, LC; Zhang, Y; Staben, ST J Med Chem 60: 627-640 (2017)
- Witten, MR; Wissler, L; Snow, M; Geschwindner, S; Read, JA; Brandon, NJ; Nairn, AC; Lombroso, PJ; Käck, H; Ellman, JA J Med Chem 60: 9299-9319 (2017)
- El-Kabbani, O; Dhagat, U; Soda, M; Endo, S; Matsunaga, T; Hara, A Bioorg Med Chem Lett 21: 2564-7 (2011)
- Pinheiro, F; Pallarčs, I; Peccati, F; Sánchez-Morales, A; Varejăo, N; Bezerra, F; Ortega-Alarcon, D; Gonzalez, D; Osorio, M; Navarro, S; Velázquez-Campoy, A; Almeida, MR; Reverter, D; Busqué, F; Alibés, R; Sodupe, M; Ventura, S J Med Chem 65: 14673-14691 (2022)
- Buzard, DJ; Lopez, L; Moody, J; Kawasaki, A; Schrader, TO; Kasem, M; Johnson, B; Zhu, X; Thoresen, L; Kim, SH; Gharbaoui, T; Sengupta, D; Calvano, L; Krishnan, A; Gao, Y; Semple, G; Edwards, J; Barden, J; Morgan, M; Usmani, K; Chen, C; Sadeque, A; Chen, W; Christopher, RJ; Thatte, J; Fu, L; Solomon, M; Whelan, K; Al-Shamma, H; Gatlin, J; Gaidarov, I; Anthony, T; Le, M; Unett, DJ; Stirn, S; Blackburn, A; Behan, DP; Jones, RM ACS Med Chem Lett 5: 1334-9 (2014)
- Andrés, JI; Alonso, JM; Díaz, A; Fernández, J; Iturrino, L; Martínez, P; Matesanz, E; Freyne, EJ; Deroose, F; Boeckx, G; Petit, D; Diels, G; Megens, A; Somers, M; Van Wauwe, J; Stoppie, P; Cools, M; De Clerck, F; Peeters, D; de Chaffoy, D Bioorg Med Chem Lett 12: 653-8 (2002)
- Lorthiois, E; Gerspacher, M; Beyer, KS; Vaupel, A; Leblanc, C; Stringer, R; Weiss, A; Wilcken, R; Guthy, DA; Lingel, A; Bomio-Confaglia, C; Machauer, R; Rigollier, P; Ottl, J; Arz, D; Bernet, P; Desjonqueres, G; Dussauge, S; Kazic-Legueux, M; Lozac'h, MA; Mura, C; Sorge, M; Todorov, M; Warin, N; Zink, F; Voshol, H; Zecri, FJ; Sedrani, RC; Ostermann, N; Brachmann, SM; Cotesta, S J Med Chem 65: 16173-16203 (2022)
- Focken, T; Burford, K; Grimwood, ME; Zenova, A; Andrez, JC; Gong, W; Wilson, M; Taron, M; Decker, S; Lofstrand, V; Chowdhury, S; Shuart, N; Lin, S; Goodchild, SJ; Young, C; Soriano, M; Tari, PK; Waldbrook, M; Nelkenbrecher, K; Kwan, R; Lindgren, A; de Boer, G; Lee, S; Sojo, L; DeVita, RJ; Cohen, CJ; Wesolowski, SS; Johnson, JP; Dehnhardt, CM; Empfield, JR J Med Chem 62: 9618-9641 (2019)
- Haßfeld, J; Kinzel, T; Köbberling, J; Cancho-Grande, Y; Beyer, K; Röhrig, S; Köllnberger, M; Sperzel, M; Burkhardt, N; Schlemmer, K; Stegmann, C; Schuhmacher, J; Werner, M; Ellermann, M US Patent US10098883 (2018)
- Spyvee, M; Satoh, T; Carlson, JE US Patent US8686018 (2014)
- Raghavan, S; Yang, Z; Mosley, RT; Schleif, WA; Gabryelski, L; Olsen, DB; Stahlhut, M; Kuo, LC; Emini, EA; Chapman, KT; Tata, JR Bioorg Med Chem Lett 12: 2855-8 (2002)
- Pelish, HE; Peterson, JR; Salvarezza, SB; Rodriguez-Boulan, E; Chen, JL; Stamnes, M; Macia, E; Feng, Y; Shair, MD; Kirchhausen, T Nat Chem Biol 2: 39-46 (2006)
- Mincione, F; Starnotti, M; Menabuoni, L; Scozzafava, A; Casini, A; Supuran, CT Bioorg Med Chem Lett 11: 1787-91 (2001)
- Guryn, R; Staszewski, M; Walczy?ski, K Med Chem Res 22: 3640-3652 (2013)
- Juli, C; Sippel, M; Jäger, J; Thiele, A; Weiwad, M; Schweimer, K; Rösch, P; Steinert, M; Sotriffer, CA; Holzgrabe, U J Med Chem 54: 277-83 (2011)
- Kunkle, T; Abdeen, S; Salim, N; Ray, AM; Stevens, M; Ambrose, AJ; Victorino, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM J Med Chem 61: 10651-10664 (2018)
- Sisay, MT; Steinmetzer, T; Stirnberg, M; Maurer, E; Hammami, M; Bajorath, J; Gütschow, M J Med Chem 53: 5523-35 (2010)
- Jones, A; Kemp, M; Stockley, M; Gibson, K; Whitlock, G US Patent US11053198 (2021)
- Moravec, J; Krystof, V; Hanus, J; Havlícek, L; Moravcová, D; Fuksová, K; Kuzma, M; Lenobel, R; Otyepka, M; Strnad, M Bioorg Med Chem Lett 13: 2993-6 (2003)
- Stucchi, M; Gmeiner, P; Huebner, H; Rainoldi, G; Sacchetti, A; Silvani, A; Lesma, G ACS Med Chem Lett 6: 882-7 (2015)
- Ioannidis, S; Lamb, ML; Wang, T; Almeida, L; Block, MH; Davies, AM; Peng, B; Su, M; Zhang, HJ; Hoffmann, E; Rivard, C; Green, I; Howard, T; Pollard, H; Read, J; Alimzhanov, M; Bebernitz, G; Bell, K; Ye, M; Huszar, D; Zinda, M J Med Chem 54: 262-76 (2011)
- Goi, T; Nakajima, T; Komatsu, Y; Kawata, A; Yamakoshi, S; Okada, O; Sugahara, M; Umeda, A; Takada, Y; Murakami, J; Ohashi, R; Watanabe, T; Fukase, K ACS Med Chem Lett 11: 1416-1420 (2020)
- Quinn, RJ; Taylor, C; Suganuma, M; Fujiki, H Bioorg Med Chem Lett 3: 1029-1034 (1993)
- Yoshikawa, K; Kobayashi, S; Nakamoto, Y; Haginoya, N; Komoriya, S; Yoshino, T; Nagata, T; Mochizuki, A; Watanabe, K; Suzuki, M; Kanno, H; Ohta, T Bioorg Med Chem 17: 8221-33 (2009)
- Bouaboula, M; Brollo, M; Certal, V; El-Ahmad, Y; Filoche-Romme, B; Halley, F; McCort, G; Schio, L; Tabart, M; Terrier, C; Thompson, F US Patent US9714221 (2017)
- Taguchi, M; Sugimoto, K; Goda, K; Akama, T; Yamamoto, K; Suzuki, T; Tomishima, Y; Nishiguchi, M; Arai, K; Takahashi, K; Kobori, T Bioorg Med Chem Lett 13: 1963-6 (2003)
- Taha, M; Ismail, NH; Imran, S; Wadood, A; Rahim, F; Riaz, M Bioorg Med Chem 23: 7211-8 (2015)
- Salah, M; Tahoun, M; Rudzitis-Auth, J; Stotz, L; van Koppen, CJ; Laschke, MW; Abdelsamie, AS; Frotscher, M J Med Chem 66: 8975-8992 (2023)
- Yoshikawa, K; Yoshino, T; Yokomizo, Y; Uoto, K; Naito, H; Kawakami, K; Mochizuki, A; Nagata, T; Suzuki, M; Kanno, H; Takemura, M; Ohta, T Bioorg Med Chem Lett 21: 2133-40 (2011)
- Wan, ZK; Follows, B; Kirincich, S; Wilson, D; Binnun, E; Xu, W; Joseph-McCarthy, D; Wu, J; Smith, M; Zhang, YL; Tam, M; Erbe, D; Tam, S; Saiah, E; Lee, J Bioorg Med Chem Lett 17: 2913-20 (2007)
- Tami, M; Dale, R; Brock, S; Jocelyn, W WIPO WO2022109580 (2022)
- Zwaagstra, ME; Timmerman, H; Tamura, M; Tohma, T; Wada, Y; Onogi, K; Zhang, MQ J Med Chem 40: 1075-89 (1997)
- Wu, T; Nagle, A; Kuhen, K; Gagaring, K; Borboa, R; Francek, C; Chen, Z; Plouffe, D; Goh, A; Lakshminarayana, SB; Wu, J; Ang, HQ; Zeng, P; Kang, ML; Tan, W; Tan, M; Ye, N; Lin, X; Caldwell, C; Ek, J; Skolnik, S; Liu, F; Wang, J; Chang, J; Li, C; Hollenbeck, T; Tuntland, T; Isbell, J; Fischli, C; Brun, R; Rottmann, M; Dartois, V; Keller, T; Diagana, T; Winzeler, E; Glynne, R; Tully, DC; Chatterjee, AK J Med Chem 54: 5116-30 (2011)
- Bradner, JE; Qi, J; Tanaka, M US Patent US11406645 (2022)
- Kiyokawa, S; Hirata, Y; Nagaoka, Y; Shibano, M; Taniguchi, M; Yasuda, M; Baba, K; Uesato, S Bioorg Med Chem 18: 3925-33 (2010)
- Tao, M; Boer, J US Patent US11407750 (2022)
- Piemontese, L; Fracchiolla, G; Carrieri, A; Parente, M; Laghezza, A; Carbonara, G; Sblano, S; Tauro, M; Gilardi, F; Tortorella, P; Lavecchia, A; Crestani, M; Desvergne, B; Loiodice, F Eur J Med Chem 90: 583-94 (2015)
- Ananthan, S; Saini, SK; Zhou, G; Hobrath, JV; Padmalayam, I; Zhai, L; Bostwick, JR; Antonio, T; Reith, ME; McDowell, S; Cho, E; McAleer, L; Taylor, M; Luedtke, RR J Med Chem 57: 7042-60 (2014)
- Carroll, C; Goldby, A; Teall, M US Patent US9475795 (2016)
- Teng, M; Nammalwar, B; Li, X; Perez, C; Yule, I; Faulkner, A; Atton, H; Parkes, A; Convers-Reignier, S; Southey, M; Puerta, DT US Patent US11407740 (2022)
- Kontopidis, G; McInnes, C; Pandalaneni, SR; McNae, I; Gibson, D; Mezna, M; Thomas, M; Wood, G; Wang, S; Walkinshaw, MD; Fischer, PM Chem Biol 13: 201-11 (2006)
- Chan, WN; Evans, JM; Hadley, MS; Herdon, HJ; Jerman, JC; Parsons, AA; Read, SJ; Stean, TO; Thompson, M; Upton, N Bioorg Med Chem Lett 9: 285-90 (1999)
- Ledneczki, I; Horváth, A; Tapolcsányi, P; Éles, J; Molnár, KD; Vágó, I; Visegrády, A; Kiss, L; Szigetvári, Á; Kóti, J; Krámos, B; Mahó, S; Holm, P; Kolok, S; Fodor, L; Thán, M; Kostyalik, D; Balázs, O; Vastag, M; Greiner, I; Lévay, G; Lendvai, B; Némethy, Z Eur J Med Chem 222: (2021)
- Schmidt, B; Lindman, S; Tong, W; Lindeberg, G; Gogoll, A; Lai, Z; Thörnwall, M; Synnergren, B; Nilsson, A; Welch, CJ; Sohtell, M; Westerlund, C; Nyberg, F; Karlén, A; Hallberg, A J Med Chem 40: 903-19 (1997)
- Menichincheri, M; Albanese, C; Alli, C; Ballinari, D; Bargiotti, A; Caldarelli, M; Ciavolella, A; Cirla, A; Colombo, M; Colotta, F; Croci, V; D'Alessio, R; D'Anello, M; Ermoli, A; Fiorentini, F; Forte, B; Galvani, A; Giordano, P; Isacchi, A; Martina, K; Molinari, A; Moll, JK; Montagnoli, A; Orsini, P; Orzi, F; Pesenti, E; Pillan, A; Roletto, F; Scolaro, A; Tatò, M; Tibolla, M; Valsasina, B; Varasi, M; Vianello, P; Volpi, D; Santocanale, C; Vanotti, E J Med Chem 53: 7296-315 (2010)
- Kubota, K; Kurebayashi, H; Miyachi, H; Tobe, M; Onishi, M; Isobe, Y Bioorg Med Chem Lett 19: 2766-71 (2009)
- Lorthiois, E; Gerspacher, M; Beyer, KS; Vaupel, A; Leblanc, C; Stringer, R; Weiss, A; Wilcken, R; Guthy, DA; Lingel, A; Bomio-Confaglia, C; Machauer, R; Rigollier, P; Ottl, J; Arz, D; Bernet, P; Desjonqueres, G; Dussauge, S; Kazic-Legueux, M; Lozac'h, MA; Mura, C; Sorge, M; Todorov, M; Warin, N; Zink, F; Voshol, H; Zecri, FJ; Sedrani, RC; Ostermann, N; Brachmann, SM; Cotesta, S J Med Chem 65: 16173-16203 (2022)
- Konishi, A; Tokumasu, M; Suzuki, T; Koshiba, T; Ohsumi, K; Ikehara, O; Kodama, Y US Patent US8609715 (2013)
- Syrjänen, L; Kuuslahti, M; Tolvanen, M; Vullo, D; Parkkila, S; Supuran, CT Bioorg Med Chem 23: 2303-9 (2015)
- Tomic, M; Kundakovic, M; Butorovic, B; Janac, B; Andric, D; Roglic, G; Ignjatovic, D; Kostic-Rajacic, S Bioorg Med Chem Lett 14: 4263-6 (2004)
- Carballa, DM; Seoane, S; Zacconi, F; Pérez, X; Rumbo, A; Alvarez-Díaz, S; Larriba, MJ; Pérez-Fernández, R; Muñoz, A; Maestro, M; Mouriño, A; Torneiro, M J Med Chem 55: 8642-56 (2012)
- Toure, M; Johnson, T; Li, B; Schmidt, R; Ma, H; Neagu, C; Lopez, AU; Wang, Y; Guler, S; Xiao, Y; Henkes, R; Ho, K; Zhang, S; Chu, CL; Gundra, UM; Porichis, F; Li, L; Maurer, CK; Fang, Z; Musil, D; DiPoto, M; Friis, E; Jones, R; Jones, C; Cummings, J; Chekler, E; Tanzer, EM; Huck, B; Sherer, B Bioorg Med Chem 92: (2023)
- Cirillo, PF; Hickey, ER; Moss, N; Breitfelder, S; Betageri, R; Fadra, T; Gaenzler, F; Gilmore, T; Goldberg, DR; Kamhi, V; Kirrane, T; Kroe, RR; Madwed, J; Moriak, M; Netherton, M; Pargellis, CA; Patel, UR; Qian, KC; Sharma, R; Sun, S; Swinamer, A; Torcellini, C; Takahashi, H; Tsang, M; Xiong, Z Bioorg Med Chem Lett 19: 2386-91 (2009)
- Fardis, M; Jin, H; Jabri, S; Cai, RZ; Mish, M; Tsiang, M; Kim, CU Bioorg Med Chem Lett 16: 4031-5 (2006)
- Anzai, H; Terai, T; Wakabayashi-Nakao, K; Noguchi, T; Kumachi, S; Tsuchiya, M; Nemoto, N ACS Med Chem Lett 12: 1427-1434 (2021)
- Uchida, T; Koshino, H; Takahashi, S; Shimizu, E; Takahashi, H; Yoshida, J; Shinden, H; Tsujimura, M; Kofujita, H; Uesugi, S; Kimura, KI J Nat Prod 81: 1070-1074 (2018)
- Parcella, K; Eastman, K; Yeung, KS; Grant-Young, KA; Zhu, J; Wang, T; Zhang, Z; Yin, Z; Parker, D; Mosure, K; Fang, H; Wang, YK; Lemm, J; Zhuo, X; Hanumegowda, U; Liu, M; Rigat, K; Donoso, M; Tuttle, M; Zvyaga, T; Haarhoff, Z; Meanwell, NA; Soars, MG; Roberts, SB; Kadow, JF ACS Med Chem Lett 8: 771-774 (2017)
- Harada, K; Mizukami, J; Watanabe, T; Mori, G; Ubukata, M; Suwa, K; Fukuda, S; Negoro, T; Sato, M; Inaba, T Bioorg Med Chem Lett 29: 2100-2106 (2019)
- Labadie, S; Dragovich, PS; Chen, J; Fauber, BP; Boggs, J; Corson, LB; Ding, CZ; Eigenbrot, C; Ge, H; Ho, Q; Lai, KW; Ma, S; Malek, S; Peterson, D; Purkey, HE; Robarge, K; Salphati, L; Sideris, S; Ultsch, M; VanderPorten, E; Wei, B; Xu, Q; Yen, I; Yue, Q; Zhang, H; Zhang, X; Zhou, A Bioorg Med Chem Lett 25: 75-82 (2015)
- Teno, N; Yamashita, Y; Masuda, A; Iguchi, Y; Oda, K; Fujimori, K; Hiramoto, T; Nishimaki-Mogami, T; Une, M; Gohda, K Bioorg Med Chem 27: 2220-2227 (2019)
- Wu, MY; Esteban, G; Brogi, S; Shionoya, M; Wang, L; Campiani, G; Unzeta, M; Inokuchi, T; Butini, S; Marco-Contelles, J Eur J Med Chem 121: 864-879 (2016)
- Mamolo, MG; Zampieri, D; Zanette, C; Florio, C; Collina, S; Urbano, M; Azzolina, O; Vio, L Eur J Med Chem 43: 2073-81 (2008)
- Fernández-Bachiller, MI; Hwang, S; Schembri, ME; Lindemann, P; Guberman, M; Herziger, S; Specker, E; Matter, H; Will, DW; Czech, J; Wagner, M; Bauer, A; Schreuder, H; Ritter, K; Urmann, M; Wehner, V; Sun, H; Nazaré, M J Med Chem 65: 13013-13028 (2022)
- Mallinger, A; Schiemann, K; Rink, C; Stieber, F; Calderini, M; Crumpler, S; Stubbs, M; Adeniji-Popoola, O; Poeschke, O; Busch, M; Czodrowski, P; Musil, D; Schwarz, D; Ortiz-Ruiz, MJ; Schneider, R; Thai, C; Valenti, M; de Haven Brandon, A; Burke, R; Workman, P; Dale, T; Wienke, D; Clarke, PA; Esdar, C; Raynaud, FI; Eccles, SA; Rohdich, F; Blagg, J J Med Chem 59: 1078-101 (2016)
- Colabufo, NA; Berardi, F; Perrone, R; Rapposelli, S; Digiacomo, M; Vanni, M; Balsamo, A J Med Chem 51: 1415-22 (2008)
- Pevarello, P; Traquandi, G; Bonsignori, A; McArthur, RA; Maj, R; Caccia, C; Salvati, P; Varasi, M Bioorg Med Chem Lett 9: 1783-8 (1999)
- Gualtieri, MJ; Malafronte, N; Vassallo, A; Braca, A; Cotugno, R; Vasaturo, M; De Tommasi, N; Dal Piaz, F J Nat Prod 77: 596-602 (2014)
- Ledneczki, I; Horváth, A; Tapolcsányi, P; Éles, J; Molnár, KD; Vágó, I; Visegrády, A; Kiss, L; Szigetvári, Á; Kóti, J; Krámos, B; Mahó, S; Holm, P; Kolok, S; Fodor, L; Thán, M; Kostyalik, D; Balázs, O; Vastag, M; Greiner, I; Lévay, G; Lendvai, B; Némethy, Z Eur J Med Chem 222: (2021)
- de Lera Ruiz, M; Favuzza, P; Guo, Z; Zhao, L; Hu, B; Lei, Z; Zhan, D; Murgolo, N; Boyce, CW; Vavrek, M; Thompson, J; Ngo, A; Jarman, KE; Robbins, J; Boddey, J; Sleebs, BE; Lowes, KN; Cowman, AF; Olsen, DB; McCauley, JA ACS Med Chem Lett 13: 1745-1754 (2022)
- Hammitzsch, A; Tallant, C; Fedorov, O; O'Mahony, A; Brennan, PE; Hay, DA; Martinez, FO; Al-Mossawi, MH; de Wit, J; Vecellio, M; Wells, C; Wordsworth, P; Müller, S; Knapp, S; Bowness, P Proc Natl Acad Sci U S A 112: 10768-73 (2015)
- Butler, KV; Ma, A; Yu, W; Li, F; Tempel, W; Babault, N; Pittella-Silva, F; Shao, J; Wang, J; Luo, M; Vedadi, M; Brown, PJ; Arrowsmith, CH; Jin, J J Med Chem 59: 9881-9889 (2016)
- Rojas, S; Parravicini, O; Vettorazzi, M; Tosso, R; Garro, A; Gutiérrez, L; Andújar, S; Enriz, R Eur J Med Chem 208: (2020)
- Preuss, J; Maloney, P; Peddibhotla, S; Hedrick, MP; Hershberger, P; Gosalia, P; Milewski, M; Li, YL; Sugarman, E; Hood, B; Suyama, E; Nguyen, K; Vasile, S; Sergienko, E; Mangravita-Novo, A; Vicchiarelli, M; McAnally, D; Smith, LH; Roth, GP; Diwan, J; Chung, TD; Jortzik, E; Rahlfs, S; Becker, K; Pinkerton, AB; Bode, L J Med Chem 55: 7262-72 (2012)
- Dossetter, AG; Beeley, H; Bowyer, J; Cook, CR; Crawford, JJ; Finlayson, JE; Heron, NM; Heyes, C; Highton, AJ; Hudson, JA; Jestel, A; Kenny, PW; Krapp, S; Martin, S; MacFaul, PA; McGuire, TM; Gutierrez, PM; Morley, AD; Morris, JJ; Page, KM; Ribeiro, LR; Sawney, H; Steinbacher, S; Smith, C; Vickers, M J Med Chem 55: 6363-74 (2012)
- Courme, C; Gresh, N; Vidal, M; Lenoir, C; Garbay, C; Florent, JC; Bertounesque, E Eur J Med Chem 45: 244-55 (2010)
- Wang, Y; Liu, JJ; Dransfield, PJ; Zhu, L; Wang, Z; Du, X; Jiao, X; Su, Y; Li, AR; Brown, SP; Kasparian, A; Vimolratana, M; Yu, M; Pattaropong, V; Houze, JB; Swaminath, G; Tran, T; Nguyen, K; Guo, Q; Zhang, J; Zhuang, R; Li, F; Miao, L; Bartberger, MD; Correll, TL; Chow, D; Wong, S; Luo, J; Lin, DC; Medina, JC ACS Med Chem Lett 4: 551-5 (2013)
- Shawn, C; Paul, CD; Lee, DR; Andrew, F; Magdalena, K; Yvette, LS; Timothy, LA; Vincent, M; Walter, PD; Andre, S; Mike, TM; Tao, W; Maria, WH WIPO WO2022112919 (2022)
- Lanni, TB; Greene, KL; Kolz, CN; Para, KS; Visnick, M; Mobley, JL; Dudley, DT; Baginski, TJ; Liimatta, MB Bioorg Med Chem Lett 17: 756-60 (2007)
- Papillon, JPN; Nakajima, K; Adair, CD; Hempel, J; Jouk, AO; Karki, RG; Mathieu, S; Möbitz, H; Ntaganda, R; Smith, T; Visser, M; Hill, SE; Hurtado, FK; Chenail, G; Bhang, HC; Bric, A; Xiang, K; Bushold, G; Gilbert, T; Vattay, A; Dooley, J; Costa, EA; Park, I; Li, A; Farley, D; Lounkine, E; Yue, QK; Xie, X; Zhu, X; Kulathila, R; King, D; Hu, T; Vulic, K; Cantwell, J; Luu, C; Jagani, Z J Med Chem 61: 10155-10172 (2018)
- Fernández-Bachiller, MI; Hwang, S; Schembri, ME; Lindemann, P; Guberman, M; Herziger, S; Specker, E; Matter, H; Will, DW; Czech, J; Wagner, M; Bauer, A; Schreuder, H; Ritter, K; Urmann, M; Wehner, V; Sun, H; Nazaré, M J Med Chem 65: 13013-13028 (2022)
- Fukuda, M; Sasaki, T; Hashimoto, T; Miyachi, H; Waki, M; Asai, A; Takikawa, O; Ohno, O; Matsuno, K Bioorg Med Chem Lett 28: 2846-2849 (2018)
- Inoue, A; Kawai, T; Wakita, M; Iimura, Y; Sugimoto, H; Kawakami, Y J Med Chem 39: 4460-70 (1996)
- Focken, T; Burford, K; Grimwood, ME; Zenova, A; Andrez, JC; Gong, W; Wilson, M; Taron, M; Decker, S; Lofstrand, V; Chowdhury, S; Shuart, N; Lin, S; Goodchild, SJ; Young, C; Soriano, M; Tari, PK; Waldbrook, M; Nelkenbrecher, K; Kwan, R; Lindgren, A; de Boer, G; Lee, S; Sojo, L; DeVita, RJ; Cohen, CJ; Wesolowski, SS; Johnson, JP; Dehnhardt, CM; Empfield, JR J Med Chem 62: 9618-9641 (2019)
- Wu, SC; Yoon, D; Chin, J; van Kirk, K; Seethala, R; Golla, R; He, B; Harrity, T; Kunselman, LK; Morgan, NN; Ponticiello, RP; Taylor, JR; Zebo, R; Harper, TW; Li, W; Wang, M; Zhang, L; Sleczka, BG; Nayeem, A; Sheriff, S; Camac, DM; Morin, PE; Everlof, JG; Li, YX; Ferraro, CA; Kieltyka, K; Shou, W; Vath, MB; Zvyaga, TA; Gordon, DA; Robl, JA Bioorg Med Chem Lett 21: 6693-8 (2011)
- Ishida, J; Yamamoto, H; Kido, Y; Kamijo, K; Murano, K; Miyake, H; Ohkubo, M; Kinoshita, T; Warizaya, M; Iwashita, A; Mihara, K; Matsuoka, N; Hattori, K Bioorg Med Chem 14: 1378-90 (2006)
- Tber, Z; Wartenberg, M; Jacques, JE; Roy, V; Lecaille, F; Warszycki, D; Bojarski, AJ; Lalmanach, G; Agrofoglio, LA Bioorg Med Chem 26: 4310-4319 (2018)
- Yan, VC; Yang, KL; Ballato, ES; Khadka, S; Shrestha, P; Arthur, K; Georgiou, DK; Washington, M; Tran, T; Poral, AH; Pham, CD; Yan, MJ; Muller, FL ACS Med Chem Lett 11: 1484-1489 (2020)
- Keith, JM; Jones, WM; Pierce, JM; Seierstad, M; Palmer, JA; Webb, M; Karbarz, MJ; Scott, BP; Wilson, SJ; Luo, L; Wennerholm, ML; Chang, L; Brown, SM; Rizzolio, M; Rynberg, R; Chaplan, SR; Breitenbucher, JG Bioorg Med Chem Lett 24: 737-41 (2014)
- Zhang, N; Zhang, X; Zhu, J; Turpoff, A; Chen, G; Morrill, C; Huang, S; Lennox, W; Kakarla, R; Liu, R; Li, C; Ren, H; Almstead, N; Venkatraman, S; Njoroge, FG; Gu, Z; Clausen, V; Graci, J; Jung, SP; Zheng, Y; Colacino, JM; Lahser, F; Sheedy, J; Mollin, A; Weetall, M; Nomeir, A; Karp, GM J Med Chem 57: 2121-35 (2014)
- Meena, CL; Singh, D; Weinmüller, M; Reichart, F; Dangi, A; Marelli, UK; Zahler, S; Sanjayan, GJ Bioorg Med Chem Lett 30: (2020)
- Juli, C; Sippel, M; Jäger, J; Thiele, A; Weiwad, M; Schweimer, K; Rösch, P; Steinert, M; Sotriffer, CA; Holzgrabe, U J Med Chem 54: 277-83 (2011)
- Jones, LH; Allan, G; Barba, O; Burt, C; Corbau, R; Dupont, T; Knöchel, T; Irving, S; Middleton, DS; Mowbray, CE; Perros, M; Ringrose, H; Swain, NA; Webster, R; Westby, M; Phillips, C J Med Chem 52: 1219-23 (2009)
- Moss, N; Choi, Y; Cogan, D; Flegg, A; Kahrs, A; Loke, P; Meyn, O; Nagaraja, R; Napier, S; Parker, A; Thomas Peterson, J; Ramsden, P; Sarko, C; Skow, D; Tomlinson, J; Tye, H; Whitaker, M Bioorg Med Chem Lett 19: 2206-10 (2009)
- Adler, M; Davey, DD; Phillips, GB; Kim, SH; Jancarik, J; Rumennik, G; Light, DR; Whitlow, M Biochemistry 39: 12534-42 (2000)
- Whittaker, M; Thompson, TM; Spavold, ZM; Price, M; Miller, A; Galloway, W; Fraser, F; Floyd, CD; Drummond, AH; Davidson, AH; Bowles, SA; Bebbington, DS Bioorg Med Chem Lett 3: 1493-1498 (1993)
- Kalaba, P; Aher, NY; Ili?, M; Draga?evi?, V; Wieder, M; Miklosi, AG; Zehl, M; Wackerlig, J; Roller, A; Beryozkina, T; Radoman, B; Saroja, SR; Lindner, W; Gonzalez, EP; Bakulev, V; Leban, JJ; Sitte, HH; Urban, E; Langer, T; Lubec, G J Med Chem 60: 9330-9348 (2017)
- Krapf, MK; Gallus, J; Namasivayam, V; Wiese, M J Med Chem 61: 7952-7976 (2018)
- Burgess, A; Wigan, M; Giles, N; Depinto, W; Gillespie, P; Stevens, F; Gabrielli, B J Biol Chem 281: 9987-95 (2006)
- Wijtmans, M; Verzijl, D; Bergmans, S; Lai, M; Bosch, L; Smit, MJ; de Esch, IJ; Leurs, R Bioorg Med Chem 19: 3384-93 (2011)
- Altenbach, RJ; Khilevich, A; Meyer, MD; Buckner, SA; Milicic, I; Daza, AV; Brune, ME; O'Neill, AB; Gauvin, DM; Cain, JC; Nakane, M; Holladay, MW; Williams, M; Brioni, JD; Sullivan, JP J Med Chem 45: 4395-7 (2002)
- Kuduk, SD; Chang, RK; Greshock, TJ; Ray, WJ; Ma, L; Wittmann, M; Seager, MA; Koeplinger, KA; Thompson, CD; Hartman, GD; Bilodeau, MT ACS Med Chem Lett 3: 1070-1074 (2012)
- Klein, T; Abgottspon, D; Wittwer, M; Rabbani, S; Herold, J; Jiang, X; Kleeb, S; Lüthi, C; Scharenberg, M; Bezençon, J; Gubler, E; Pang, L; Smiesko, M; Cutting, B; Schwardt, O; Ernst, B J Med Chem 53: 8627-41 (2010)
- Maga, G; Falchi, F; Garbelli, A; Belfiore, A; Witvrouw, M; Manetti, F; Botta, M J Med Chem 51: 6635-8 (2008)
- Borsari, C; Jiménez-Antón, MD; Eick, J; Bifeld, E; Torrado, JJ; Olías-Molero, AI; Corral, MJ; Santarem, N; Baptista, C; Severi, L; Gul, S; Wolf, M; Kuzikov, M; Ellinger, B; Reinshagen, J; Witt, G; Linciano, P; Tait, A; Costantino, L; Luciani, R; Tejera Nevado, P; Zander-Dinse, D; Franco, CH; Ferrari, S; Moraes, CB; Cordeiro-da-Silva, A; Ponterini, G; Clos, J; Alunda, JM; Costi, MP Eur J Med Chem 183: (2019)
- Mesleh, MF; Cross, JB; Zhang, J; Kahmann, J; Andersen, OA; Barker, J; Cheng, RK; Felicetti, B; Wood, M; Hadfield, AT; Scheich, C; Moy, TI; Yang, Q; Shotwell, J; Nguyen, K; Lippa, B; Dolle, R; Ryan, MD Bioorg Med Chem Lett 26: 1314-8 (2016)
- Metobo, S; Mish, M; Jin, H; Jabri, S; Lansdown, R; Chen, X; Tsiang, M; Wright, M; Kim, CU Bioorg Med Chem Lett 19: 1187-90 (2009)
- Mattmann, ME; Yu, H; Lin, Z; Xu, K; Huang, X; Long, S; Wu, M; McManus, OB; Engers, DW; Le, UM; Li, M; Lindsley, CW; Hopkins, CR Bioorg Med Chem Lett 22: 5936-41 (2012)
- Flesch, D; Cheung, SY; Schmidt, J; Gabler, M; Heitel, P; Kramer, J; Kaiser, A; Hartmann, M; Lindner, M; Lüddens-Dämgen, K; Heering, J; Lamers, C; Lüddens, H; Wurglics, M; Proschak, E; Schubert-Zsilavecz, M; Merk, D J Med Chem 60: 7199-7205 (2017)
- Xia, M; Hou, C; DeMong, DE; Pollack, SR; Pan, M; Brackley, JA; Jain, N; Gerchak, C; Singer, M; Malaviya, R; Matheis, M; Olini, G; Cavender, D; Wachter, M J Med Chem 50: 5561-3 (2007)
- Malwal, SR; Mazurek, B; Ko, J; Xie, P; Barnes, C; Varvitsiotis, C; Zimmerman, MD; Olatunji, S; Lee, J; Xie, M; Sarathy, J; Caffrey, M; Strynadka, NCJ; Dartois, V; Dick, T; Lee, BNR; Russell, DG; Oldfield, E J Med Chem 66: 7553-7569 (2023)
- Craig, RA; Fox, BM; Hu, C; Lexa, KW; Osipov, M; Thottumkara, AP; Larhammar, M; Miyamoto, T; Rana, A; Kane, LA; Yulyaningsih, E; Solanoy, H; Nguyen, H; Chau, R; Earr, T; Kajiwara, Y; Fleck, D; Lucas, A; Haddick, PCG; Takahashi, RH; Tong, V; Wang, J; Canet, MJ; Poda, SB; Scearce-Levie, K; Srivastava, A; Sweeney, ZK; Xu, M; Zhang, R; He, J; Lei, Y; Zhuo, Z; de Vicente, J J Med Chem 65: 16290-16312 (2022)
- Kaller, MR; Harried, SS; Albrecht, B; Amarante, P; Babu-Khan, S; Bartberger, MD; Brown, J; Brown, R; Chen, K; Cheng, Y; Citron, M; Croghan, MD; Graceffa, R; Hickman, D; Judd, T; Kriemen, C; La, D; Li, V; Lopez, P; Luo, Y; Masse, C; Monenschein, H; Nguyen, T; Pennington, LD; Miguel, TS; Sickmier, EA; Wahl, RC; Weiss, MM; Wen, PH; Williamson, T; Wood, S; Xue, M; Yang, B; Zhang, J; Patel, V; Zhong, W; Hitchcock, S ACS Med Chem Lett 3: 886-891 (2012)
- Yamada, M; Okagaki, C; Higashijima, T; Tanaka, S; Ohnuki, T; Sugita, T Bioorg Med Chem Lett 8: 1537-40 (1999)
- Yamaguchi, M; Kamei, K; Koga, T; Akima, M; Maruyama, A; Kuroki, T; Ohi, N J Med Chem 36: 4061-8 (1994)
- Hayakawa, M; Kaizawa, H; Kawaguchi, K; Ishikawa, N; Koizumi, T; Ohishi, T; Yamano, M; Okada, M; Ohta, M; Tsukamoto, S; Raynaud, FI; Waterfield, MD; Parker, P; Workman, P Bioorg Med Chem 15: 403-12 (2007)
- Ishikawa, M; Watanabe, T; Kudo, T; Yokoyama, F; Yamauchi, M; Kato, K; Kakui, N; Sato, Y J Med Chem 53: 6445-56 (2010)
- Buchanan, JL; Vu, CB; Merry, TJ; Corpuz, EG; Pradeepan, SG; Mani, UN; Yang, M; Plake, HR; Varkhedkar, VM; Lynch, BA; MacNeil, IA; Loiacono, KA; Tiong, CL; Holt, DA Bioorg Med Chem Lett 9: 2359-64 (1999)
- Kiyokawa, S; Hirata, Y; Nagaoka, Y; Shibano, M; Taniguchi, M; Yasuda, M; Baba, K; Uesato, S Bioorg Med Chem 18: 3925-33 (2010)
- Proudfoot, JR; Betageri, R; Cardozo, M; Gilmore, TA; Glynn, S; Hickey, ER; Jakes, S; Kabcenell, A; Kirrane, TM; Tibolla, AK; Lukas, S; Patel, UR; Sharma, R; Yazdanian, M; Moss, N; Beaulieu, PL; Cameron, DR; Ferland, JM; Gauthier, J; Gillard, J; Gorys, V; Poirier, M; Rancourt, J; Wernic, D; Llinas-Brunet, M J Med Chem 44: 2421-31 (2001)
- Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y J Med Chem 51: 5650-62 (2008)
- Hodgson, ST; Wates, PJ; Blackwell, GJ; Craig, C; Yeadon, M; Boughton-Smith, N Bioorg Med Chem Lett 3: 2565-2570 (1993)
- Kwag, R; Lee, J; Kim, D; Lee, H; Yeom, M; Woo, J; Cho, Y; Kim, HJ; Kim, J; Keum, G; Jeon, B; Choo, H J Med Chem 64: 13766-13779 (2021)
- Cheung, AW; Danho, W; Swistok, J; Qi, L; Kurylko, G; Rowan, K; Yeon, M; Franco, L; Chu, XJ; Chen, L; Yagaloff, K Bioorg Med Chem Lett 13: 133-7 (2002)
- Miwa, S; Yokota, M; Ueyama, Y; Maeda, K; Ogoshi, Y; Seki, N; Ogawa, N; Nishihata, J; Nomura, A; Adachi, T; Kitao, Y; Nozawa, K; Ishikawa, T; Ukaji, Y; Shiozaki, M ACS Med Chem Lett 12: 745-751 (2021)
- Wang, A; Prouty, CP; Pelton, PD; Yong, M; Demarest, KT; Murray, WV; Kuo, GH Bioorg Med Chem Lett 20: 1432-5 (2010)
- Yoshikawa, M; Saitoh, M; Kato, T; Nakayama, Y; Seki, T; Nakagawa, Y; Tominari, Y; Seto, M; Sasaki, Y; Okaniwa, M; Oda, T; Shibuya, A; Hidaka, K; Shiokawa, Z; Murata, S; Okabe, A; Nakada, Y; Mochizuki, M; Freeze, BS; Tawaraishi, T; Wada, Y; Greenspan, PD US Patent US11666594 (2023)
- Imbriglio, JE; Shen, DM; Liang, R; Marby, K; You, M; Youm, HW; Feng, Z; London, C; Xiong, Y; Tata, J; Verras, A; Garcia-Calvo, M; Song, X; Addona, GH; McLaren, DG; He, T; Murphy, B; Metzger, DE; Salituro, G; Deckman, D; Chen, Q; Jin, X; Stout, SJ; Wang, SP; Wilsie, L; Palyha, O; Han, S; Hubbard, BK; Previs, SF; Pinto, S; Taggart, A J Med Chem 58: 9345-53 (2015)
- Asghar, A; Yousuf, M; Mubeen, H; Nazir, R; Haruna, K; Onawole, AT; Rasheed, L Bioorg Med Chem 27: 2397-2404 (2019)
- Wang, Y; Liu, JJ; Dransfield, PJ; Zhu, L; Wang, Z; Du, X; Jiao, X; Su, Y; Li, AR; Brown, SP; Kasparian, A; Vimolratana, M; Yu, M; Pattaropong, V; Houze, JB; Swaminath, G; Tran, T; Nguyen, K; Guo, Q; Zhang, J; Zhuang, R; Li, F; Miao, L; Bartberger, MD; Correll, TL; Chow, D; Wong, S; Luo, J; Lin, DC; Medina, JC ACS Med Chem Lett 4: 551-5 (2013)
- ZHANG, C; XIA, G; XIANG, Z; KE, Y; LOU, J; ZHAO, M; HAO, L US Patent US20240101552 (2024)
- Le Manach, C; Nchinda, AT; Paquet, T; Gonzŕlez Cabrera, D; Younis, Y; Han, Z; Bashyam, S; Zabiulla, M; Taylor, D; Lawrence, N; White, KL; Charman, SA; Waterson, D; Witty, MJ; Wittlin, S; Botha, ME; Nondaba, SH; Reader, J; Birkholtz, LM; Jiménez-Díaz, MB; Martínez, MS; Ferrer, S; Angulo-Barturen, I; Meister, S; Antonova-Koch, Y; Winzeler, EA; Street, LJ; Chibale, K J Med Chem 59: 9890-9905 (2016)
- Stefanowicz, J; S?owi?ski, T; Wróbel, MZ; Herold, F; Gomó?ka, AE; Weso?owska, A; Jastrz?bska-Wi?sek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; ?uszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; ?o?nierek, M; B?czek, T; Ulenberg, S; Belka, M; Tur?o, J Bioorg Med Chem 24: 3994-4007 (2016)
- Starck, JP; Talaga, P; Quéré, L; Collart, P; Christophe, B; Lo Brutto, P; Jadot, S; Chimmanamada, D; Zanda, M; Wagner, A; Mioskowski, C; Massingham, R; Guyaux, M Bioorg Med Chem Lett 16: 373-7 (2005)
- Zechner, M; Castro Jaramillo, CA; Zubler, NS; Taddio, MF; Mu, L; Altmann, KH; Krämer, SD J Med Chem 66: 6782-6797 (2023)
- Kalaba, P; Aher, NY; Ili?, M; Draga?evi?, V; Wieder, M; Miklosi, AG; Zehl, M; Wackerlig, J; Roller, A; Beryozkina, T; Radoman, B; Saroja, SR; Lindner, W; Gonzalez, EP; Bakulev, V; Leban, JJ; Sitte, HH; Urban, E; Langer, T; Lubec, G J Med Chem 60: 9330-9348 (2017)
- Zhang, K; Ji, M; Lin, S; Peng, S; Zhang, Z; Zhang, M; Zhang, J; Zhang, Y; Wu, D; Tian, H; Chen, X; Xu, H J Med Chem 64: 7331-7340 (2021)
- Zheng, M; Li, C; Zhou, M; Jia, R; Cai, G; She, F; Wei, L; Wang, S; Yu, J; Wang, D; Calcul, L; Sun, X; Luo, X; Cheng, F; Li, Q; Wang, Y; Cai, J J Med Chem 64: 11219-11228 (2021)
- Zheng, M; Li, C; Zhou, M; Jia, R; Cai, G; She, F; Wei, L; Wang, S; Yu, J; Wang, D; Calcul, L; Sun, X; Luo, X; Cheng, F; Li, Q; Wang, Y; Cai, J J Med Chem 64: 11219-11228 (2021)
- Zhu, M; Dong, B; Zhang, GN; Wang, JX; Cen, S; Wang, YC Bioorg Med Chem Lett 29: 1541-1545 (2019)
- Smethurst, CA; Bevan, N; Brooks, C; Emmons, A; Gough, PJ; Mookherjee, C; Moores, K; Peace, S; Philp, J; Piercy, V; Watson, SP; Zippoli, M Bioorg Med Chem Lett 22: 7252-5 (2012)
- Beaufils, F; Cmiljanovic, N; Cmiljanovic, V; Bohnacker, T; Melone, A; Marone, R; Jackson, E; Zhang, X; Sele, A; Borsari, C; Mestan, J; Hebeisen, P; Hillmann, P; Giese, B; Zvelebil, M; Fabbro, D; Williams, RL; Rageot, D; Wymann, MP J Med Chem 60: 7524-7538 (2017)
- Hauck, S; Hiesinger, K; Khageh Hosseini, S; Achenbach, J; Biondi, RM; Proschak, E; Zörnig, M; Odadzic, D Bioorg Med Chem 24: 5717-5729 (2016)
- Stefanowicz, J; S?owi?ski, T; Wróbel, MZ; Herold, F; Gomó?ka, AE; Weso?owska, A; Jastrz?bska-Wi?sek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; ?uszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; ?o?nierek, M; B?czek, T; Ulenberg, S; Belka, M; Tur?o, J Bioorg Med Chem 24: 3994-4007 (2016)
- ChEMBL_1541516 (CHEMBL3744079) Inhibition of oseltamivir-resistant Influenza A virus H3N2 neuraminidase
- ChEMBL_1541517 (CHEMBL3744080) Inhibition of oseltamivir-resistant Influenza A virus H3N2 neuraminidase E119V mutant
- ChEBML_1649827 Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrate
- ChEMBL_1649827 (CHEMBL3998961) Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrate
- Neuraminidase Inhibition Assay The 50% inhibitory concentration (IC50) determination was carried out by using a 96-well microtitre plate as an array of reaction vessels. In the first well,a 0.1-mM solution of oseltamivir carboxylate was prepared by mixing 90 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2 and 10 μl of a 1-mM oseltamivir carboxylate stock solution. Starting from the solution contained in the first well, an in-plate 10-fold serial dilution was performed using 33 mM MES pH 6.5 containing 4 mM CaCl2 as dilution buffer obtaining a 7 points dilution curve, the last well in the vertical lane was used to obtain a negative control (no oseltamivir was added). At the end of the dilution process, each well contained 90 μl of solution. To each well, 25 μl of the enzyme stock solution were mixed with the oseltamivir solution and incubated for 2 h at 37°C. After the incubation time, 25 μl of 20 μM MUNANA were added. In the reaction mixtures, the final concentration of oseltamivir carboxylate spanned in the ranges 0.064 nM-64.2 μM. After incubating the plate for 5 h at 37°C, 50 μl of stop solution (0.1 M Glycine, pH 10.7 containing 25% ethanol) were added. The fluorescence of the solutions contained in each well was read with the Victor3 multi-label counter. For the determination of the of oseltamivir carboxylate against neuraminidase N3, the same procedure described above was used, except for the concentrationof the oseltamivir carboxylate stock solution which was 10 μM. In the reaction mixtures, the final concentration of oseltamivir carboxylate spanned in the ranges 0.64 pM-642 nM.
- ChEMBL_1295475 (CHEMBL3131473) Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assay
- ChEMBL_819005 (CHEMBL2034237) Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant using 4-MU-NANA as substrate by fluorescence assay
- ChEMBL_698045 (CHEMBL1645796) Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant activity expressed in HEK293T cells after 2 hrs by spectrofluorometry
- ChEMBL_675041 (CHEMBL1272775) Inhibition of oseltamivir-resistant Influenza A virus (A/California/08/2009(H1N1)) neuraminidase H274Y mutant expressed in human 293T cells after 30 mins by spectrofluorimetric analysis
- Neuraminidase Activity Assay Practically in a microtitre plate, 90 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2 were dispensed in each well, except for the first well of each lane. In the first well of each vertical lane, 18 μl of 0.01 mM oseltamivir were mixed with 162 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2. The solution was thoroughly mixed to obtain a 1-μM oseltamivir carboxylate solution. For each assay, a 90-μl aliquot of this solution was withdrawn from the first well and added to the second well in the same vertical lane obtaining a 2-fold diluted solution of oseltamivir. The 2-fold dilution process was continued up to the seventh well, while the eighth well used as blank (no inhibitor was added). At the end of the dilution process, each well contained 90 μl of solution. To each well, 25 μl of enzyme stock solution were added. After an incubation time of 2 h, 25 μl of MUNANA were added to each well, the final concentrations of oseltamivir carboxylate spanned the range 10-643 nM for N1 assay. After 30 min of incubation, 50 μl of stop solution were added to the first vertical lane, and the fluorescence was recorded. After an additional 30 min (60 min total), the stop solution was added to the second vertical lane and the fluorescence recorded. After additional 30 min (90 min total), the stop solution was added to the third vertical lane and the fluorescence recorded and so on. The experiment was performed in duplicate. For the determination of oseltamivir carboxylate Ki against N3, the same procedure described for N1 was used, except for the concentration of oseltamivir carboxylate stock solution which was 0.1 μM.