BDBM50490618 Milnacipran Midalcipran
1S,2R-milnacipran BDBM50275771 CHEMBL471001
BDBM86420 Milnacipran CAS_92623-85-3 NSC_0
- Chen, C; Dyck, B; Fleck, BA; Foster, AC; Grey, J; Jovic, F; Mesleh, M; Phan, K; Tamiya, J; Vickers, T; Zhang, M Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors. Bioorg Med Chem Lett 18: 1346-9 (2008)
- Vaishnavi, SN; Nemeroff, CB; Plott, SJ; Rao, SG; Kranzler, J; Owens, MJ Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity. Biol Psychiatry 55: 320-2 (2004)
- Tamiya, J; Dyck, B; Zhang, M; Phan, K; Fleck, BA; Aparicio, A; Jovic, F; Tran, JA; Vickers, T; Grey, J; Foster, AC; Chen, C Identification of 1S,2R-milnacipran analogs as potent norepinephrine and serotonin transporter inhibitors. Bioorg Med Chem Lett 18: 3328-32 (2008)
- Roggen, H; Kehler, J; Stensbøl, TB; Hansen, T Synthesis of enantiomerically pure milnacipran analogs and inhibition of dopamine, serotonin, and norepinephrine transporters. Bioorg Med Chem Lett 17: 2834-7 (2007)
- Vickers, T; Dyck, B; Tamiya, J; Zhang, M; Jovic, F; Grey, J; Fleck, BA; Aparicio, A; Johns, M; Jin, L; Tang, H; Foster, AC; Chen, C Studies on a series of milnacipran analogs containing a heteroaromatic group as potent norepinephrine and serotonin transporter inhibitors. Bioorg Med Chem Lett 18: 3230-5 (2008)
- Dyck, B; Tamiya, J; Jovic, F; Pick, RR; Bradbury, MJ; O'Brien, J; Wen, J; Johns, M; Madan, A; Fleck, BA; Foster, AC; Li, B; Zhang, M; Tran, JA; Vickers, T; Grey, J; Saunders, J; Chen, C Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain. J Med Chem 51: 7265-72 (2009)
- Shuto, S; Ono, S; Imoto, H; Yoshii, K; Matsuda, A Synthesis and biological activity of conformationally restricted analogues of milnacipran: (1S, 2R)-1-phenyl-2-[(R)-1-amino-2-propynyl]-N,N- diethylcyclopropanecarboxamide is a novel class of NMDA receptor channel blocker. J Med Chem 41: 3507-14 (1998)
- Shuto, S; Ono, S; Hase, Y; Ueno, Y; Noguchi, T; Yoshii, K; Matsuda, A Synthesis and biological activity of conformationally restricted analogs of milnacipran: (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxami de, an efficient noncompetitive N-methyl-D-aspartic acid receptor antagonist. J Med Chem 39: 4844-52 (1997)