Query String: PHENYLEPHRINE
Phenylephrine,(-) PHENYLEPHRINE (R)-(-)-phenylephrine BDBM36024
BDBM162128 Phenylephrine,(+) (S)-(+)-phenylephrine
Phenylephrine,(+/-) BDBM162129
CHEBI:8093 Duo-Medihaler Phenylephrine Cyclomydril BDBM50067212
- Musser, JH; Kubrak, DM; Bender, RH; Kreft, AF; Nielsen, ST; Lefer, AM; Chang, J; Lewis, AJ; Hand, JM Phenylephrine derivatives as leukotriene D4 antagonists. J Med Chem 30: 2087-93 (1987)
- Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H Identification of a dihydropyridine as a potent alpha1a adrenoceptor-selective antagonist that inhibits phenylephrine-induced contraction of the human prostate. J Med Chem 41: 2643-50 (1998)
- ChEMBL_350832 (CHEMBL869686) Vasorelaxation of phenylephrine-stimulated Wistar rat aorta contraction
- ChEMBL_1655782 (CHEMBL4005252) Inhibition of L-type calcium channel in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced vasoconstriction preincubated with aortic rings followed by phenylephrine addition
- ChEMBL_310709 (CHEMBL838054) Efficacy against phenylephrine precontracted tissue relaxation in rat aorta
- ChEMBL_446237 (CHEMBL895342) Vasodilating activity against phenylephrine-induced contractions in rat thoracic aorta
- ChEMBL_310745 (CHEMBL837655) Relative efficacy against phenylephrine precontracted tissue relaxation in Guinea pig aorta
- ChEMBL_1628379 (CHEMBL3870964) Antagonist activity at adrenergic alpha1A receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux preincubated for 30 mins followed by phenylephrine addition by Fluo-4-AM-dye based FLIPR assay
- ChEMBL_1628380 (CHEMBL3870965) Antagonist activity at adrenergic alpha1B receptor (unknown origin) expressed in Rat1 cells assessed as inhibition of phenylephrine-induced Ca2+ flux preincubated for 30 mins followed by phenylephrine addition by Fluo-4-AM-dye based FLIPR assay
- ChEMBL_2079017 (CHEMBL4734808) Agonist activity at TRPV1 in rat isolated mesenteric arteries assessed as vasorelaxation of phenylephrine-induced contraction
- ChEMBL_353199 (CHEMBL865719) Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips
- ChEMBL_597656 (CHEMBL1039955) Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal artery
- ChEMBL_1448425 (CHEMBL3377453) Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction
- ChEMBL_1776694 (CHEMBL4233686) Agonist activity at endothelial M3 receptor in Wistar-Kyoto rat thoracic aortic rings assessed as inhibition of phenylephrine-induced contraction
- ChEMBL_2079018 (CHEMBL4734809) Agonist activity at TRPV1 in rat isolated mesenteric arteries assessed as vasorelaxation of phenylephrine-induced contraction in presence of TRPV1 antagonist capsazepine
- ChEMBL_353200 (CHEMBL865721) Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ
- ChEMBL_854048 (CHEMBL2155389) Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins
- ChEMBL_446229 (CHEMBL895334) Vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta in presence of 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one
- ChEMBL_1796376 (CHEMBL4268493) Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholine-induced vasorelaxation by pressure myographic method
- ChEMBL_901096 (CHEMBL3062175) Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of phenylephrine-induced vasoconstriction after 30 min relative to control