Query String: PROTRIPTYLINE
5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine PROTRIPTYLINE BDBM50176062 7-(3-methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene CHEMBL668 N-methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine amimetilina 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
- Amoxapine and Protriptyline Inhibition Assay Reaction conditions were as follows: SULT1A1 or 2A1 (50 nM), PnP (3.0 or 100 uM, respectively; 2 x Km PnP), amoxipine or protriptyline (0, 50, 100, or 300 uM), PAPS (125 uM or 3.0 mM, respectively; >250 x Km PAPS), MgCl2 (5.0 mM), KPO4 (50 mM), pH 7.5, 25 +/- 2 ° C. Sulfation of PnP was monitored optically at λ = 415 nm (ε415 = 10.6 mM-1 cm-1 at pH 7.5 [Whittemore et al., Biochemistry, 24:2477-2482).