(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid Simvastatin Simvastatin acid BDBM18375
cid_54454 MK-733 SIMVASTATIN LACTONE Simvastatin (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate Zocor BDBM50139181 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
- Hartman, GD; Halczenko, W; Duggan, ME; Imagire, JS; Smith, RL; Pitzenberger, SM; Fitzpatrick, SL; Alberts, AW; Bostedor, R; Chao, YS 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs. J Med Chem 35: 3813-21 (1992)
- Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 7. Modification of the hexahydronaphthalene moiety of simvastatin: 5-oxygenated and 5-oxa derivatives. J Med Chem 34: 2489-95 (1991)