Simple Search Results

Query String: TACRINE

CHEMBL32823 Homodimeric Tacrine Analog 3b tacrine homobivalent compound 3a BDBM8963 N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-1,2,3,4-tetrahydroacridin-9-amine Tacrine-Based Inhibitor 2f Tacrine Dimer 3b
BDBM9444 Tacrine-Based Inhibitor 2g
Tacrine-Based Inhibitor 2f BDBM9443
BDBM8964 CHEMBL75274 Homodimeric Tacrine Analog 3c Tacrine-Based Inhibitor 2g N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]-1,2,3,4-tetrahydroacridin-9-amine Tacrine Dimer 3c
BDBM29401 tacrine-dihydropyridine hybrid (tacripyrine), 12
BDBM29402 tacrine-dihydropyridine hybrid (tacripyrine), 13
BDBM29403 tacrine-dihydropyridine hybrid (tacripyrine), 14
CHEMBL484705 BDBM50292567 tacrine(8)-4-aminoquinoline
[14C]-Tacrine Monohydrate Monohydrochloride BDBM50433314 CHEMBL1337960
tacrine-dihydropyridine hybrid (tacripyrine), 3 BDBM29392
tacrine-dihydropyridine hybrid (tacripyrine), 8 BDBM29397
BDBM29400 tacrine-dihydropyridine hybrid (tacripyrine), 11 CHEMBL374184
CHEMBL219172 tacrine-dihydropyridine hybrid (tacripyrine), 2 BDBM29391
CHEMBL220294 tacrine-dihydropyridine hybrid (tacripyrine), 5 BDBM29394
CHEMBL436302 tacrine-dihydropyridine hybrid (tacripyrine), 9 BDBM29398
tacrine-dihydropyridine hybrid (tacripyrine), 1 BDBM29390 CHEMBL218939
tacrine-dihydropyridine hybrid (tacripyrine), 10 CHEMBL218940 BDBM29399
tacrine-dihydropyridine hybrid (tacripyrine), 4 BDBM29393 CHEMBL219400
tacrine-dihydropyridine hybrid (tacripyrine), 6 BDBM29395 CHEMBL219405
tacrine-dihydropyridine hybrid (tacripyrine), 7 BDBM29396 CHEMBL219406
CHEMBL51197 Tacrine Dimer 4f tacrine heterobivalent compound 3e BDBM8970 N-[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)heptyl]-1,2,3,4-tetrahydroacridin-9-amine
6,7-dichloro-1,2,3,4-tetrahydroacridin-9-amine BDBM8993 Tacrine Analogue 10
7-methyl-1,2,3,4-tetrahydroacridin-9-amine BDBM8984 Tacrine Analogue 1
BDBM8985 Tacrine Analogue 2 6-methyl-1,2,3,4-tetrahydroacridin-9-amine
BDBM8986 7-chloro-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 3
BDBM8988 7-nitro-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 5
BDBM8989 6-nitro-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 6
BDBM8994 6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 11
Tacrine Analogue 7 BDBM8990 6-methoxy-1,2,3,4-tetrahydroacridin-9-amine
Tacrine Analogue 9 6-fluoro-1,2,3,4-tetrahydroacridin-9-amine BDBM8992
N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]-1,2,3,4-tetrahydroacridin-9-amine Bis-THA inhibitor 5 Homodimeric Tacrine Analog 3a Hexylene-Linked Bis-tacrine BDBM9047 CHEMBL73800
US8999994, Tacrine 9-THA BDBM8961 1,2,3,4-tetrahydro-9-acridinamine Cognex CHEMBL1337960 cid_1935 1,2,3,4-tetrahydroacridin-9-amine CHEMBL95 Tracine 9-amino-1,2,3,4-tetrahydroacridine (THA) tacrine.HCl Tacrine
BDBM10516 6,8-dichloro-1,2,3,4-tetrahydroacridin-9-amine Tacrine deriv. 2 CHEMBL48643
6-chloro-N-{8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}-1,2,3,4-tetrahydroacridin-9-amine BDBM9055 Homodimeric Tacrine Analog 3i Octylene-Linked Bis-(6-chloro)tacrine
6-fluoro-N-{6-[(6-fluoro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-1,2,3,4-tetrahydroacridin-9-amine Homodimeric Tacrine Analog 3d BDBM9050 Hexylene-Linked Bis-(6-fluoro)tacrine
6-fluoro-N-{8-[(6-fluoro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}-1,2,3,4-tetrahydroacridin-9-amine Homodimeric Tacrine Analog 3f Octylene-Linked Bis-(6-fluoro)tacrine BDBM9052
Homodimeric Tacrine Analog 3e 6-fluoro-N-{7-[(6-fluoro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1,2,3,4-tetrahydroacridin-9-amine BDBM9051 Heptylene-Linked Bis-(6-fluoro)tacrine
Homodimeric Tacrine Analog 3g 6-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-1,2,3,4-tetrahydroacridin-9-amine Hexylene-Linked Bis-(6-chloro)tacrine BDBM9053
Homodimeric Tacrine Analog 3h Heptylene-Linked Bis-(6-chloro)tacrine 6-chloro-N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1,2,3,4-tetrahydroacridin-9-amine BDBM9054
BDBM9004 N-heptyl-6-methoxy-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 21
BDBM9005 6-fluoro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 22
N-benzyl-6-methyl-1,2,3,4-tetrahydroacridin-9-amine BDBM8996 Tacrine Analogue 13
N-benzyl-7-methyl-1,2,3,4-tetrahydroacridin-9-amine BDBM8995 Tacrine Analogue 12
N-heptyl-6-methyl-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 18 BDBM9001
N-heptyl-6-nitro-1,2,3,4-tetrahydroacridin-9-amine Tacrine Analogue 20 BDBM9003
Tacrine Analogue 16 BDBM8999 N-benzyl-6-nitro-1,2,3,4-tetrahydroacridin-9-amine
Tacrine Analogue 17 N-heptyl-7-methyl-1,2,3,4-tetrahydroacridin-9-amine BDBM9000
Tacrine Analogue 19 6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amine BDBM9002
Tacrine Analogue 8 5,6,7,8-tetrahydroacridine-2,9-diamine 7,9-Diamino-1,2,3,4-tetrahydroacridine BDBM8991
BDBM8965 methylbis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amine Tacrine Dimer 4a CHEMBL338755
BDBM8987 6-chlorotacrine 6-chlorotacrine.HCl Tacrine Analogue 4 CHEMBL486698 6-chloro-1,2,3,4-tetrahydroacridin-9-amine
CHEMBL131410 Tacrine Dimer 4e N,N-bis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]acetamide BDBM8969
tacrine homobivalent compound 3d 9-{[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)heptyl]sulfanyl}-1,2,3,4-tetrahydroacridine BDBM10520
BDBM10525 tacrine heterobivalent compound 3i N-[6-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)hexyl]-1,2,3,4-tetrahydroacridin-9-amine
N-[8-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)octyl]-1,2,3,4-tetrahydroacridin-9-amine Tacrine Dimer 4g BDBM8971 CHEMBL129108
tacrine heterobivalent compound 3j BDBM10526 N-[4-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)butyl]-1,2,3,4-tetrahydroacridin-9-amine
N-[(1-benzylpiperidin-4-yl)methyl]-2-(1,2,3,4-tetrahydroacridin-9-ylamino)acetamide tacrine-E2020 analog 4 BDBM8980
N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-[(3,4-dimethoxyphenyl)formamido]acetamide tacrine-E2020 analog 5 BDBM8981
BDBM10523 tacrine heterobivalent compound 3g 6,8-dichloro-N-[7-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)heptyl]-1,2,3,4-tetrahydroacridin-9-amine
Tacrine Analogue 15 BDBM8998 N-benzyl-7-nitro-1,2,3,4-tetrahydroacridin-9-amine 7-Nitro-9-benzylamino-1,2,3,4-tetrahydroacridine
5-(1,2-dithiolan-3-yl)-N-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]pentanamide BDBM10506 tacrine-lipoic acid hybrid 1
N-1,2,3,4-Tetrahydroacridin-9-yl-3,4,5-trimethoxybenzohydrazide BDBM13536 tacrine derivative 15a 3,4,5-trimethoxy-N'-(1,2,3,4-tetrahydroacridin-9-yl)benzohydrazide
N-heptyl-1,2,3,4-tetrahydroacridin-9-amine hydrochloride alkylated Tacrine analogue 2 BDBM10442 9-N-heptyl-amino-1,2,3,4-tetrahydroacridine hydrochloride
N-{6-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]hexyl}-1,2,3,4-tetrahydroacridin-9-amine tacrine heterobivalent compound 3h BDBM10524
N-{7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]heptyl}-1,2,3,4-tetrahydroacridin-9-amine tacrine heterobivalent compound 3f BDBM10522
tacrine-E2020 analog 3 BDBM8979 CHEMBL486901 N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-(1,2,3,4-tetrahydroacridin-9-ylamino)acetamide
tacrine-lipoic acid hybrid 2 5-(1,2-dithiolan-3-yl)-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]pentanamide BDBM10507
tacrine-lipoic acid hybrid 3 5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]pentanamide BDBM10508
tacrine-lipoic acid hybrid 4 5-(1,2-dithiolan-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]pentanamide BDBM10509
tacrine-lipoic acid hybrid 5 BDBM10510 5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]pentanamide
tacrine-lipoic acid hybrid 6 BDBM10511 5-(1,2-dithiolan-3-yl)-N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]pentanamide
(RS)-tacrine(10)-hupyridone 5-[10-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-decylamino]-5,6,7,8-tetrahydro-1H-quinolin-2-one CHEMBL76658 BDBM50080157
BDBM8975 Tacrine Dimer 4k CHEMBL179192 N-[3-(1,2,3,4-Tetrahydroacridin-9-ylamino)propyl]-N-[3-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)propyl]acetamide
BDBM8982 tacrine-E2020 analog 6 N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-(2,3-dihydro-1H-inden-1-ylamino)acetamide
Bis-THA inhibitor 4 BDBM8962 N-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]-1,2,3,4-tetrahydroacridin-9-amine Tacrine Dimer 3a CHEMBL179732
CHEMBL175949 BDBM8977 N-[3-(1,2,3,4-Tetrahydroacridin-9-ylamino)propyl]-N-[4-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)butyl]acetamide Tacrine Dimer 4m
CHEMBL51350 tacrine heterobivalent compound 3c N-{7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1,2,3,4-tetrahydroacridin-9-amine BDBM10519
BDBM8997 N-benzyl-6-chloro-1,2,3,4-tetrahydroacridin-9-amine N-Benzyl-6-chloro-1,2,3,4-tetrahydroacridin-9-amine (9a) Tacrine Analogue 14
6,8-dichloro-N-{7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1,2,3,4-tetrahydroacridin-9-amine CHEMBL53927 tacrine homobivalent compound 3b BDBM10518
BDBM13545 N-1,2,3,4-Tetrahydroacridin-9-yl-3-(3,4,5-trimethoxyphenyl)propanohydrazide tacrine derivative 16a N'-(1,2,3,4-tetrahydroacridin-9-yl)-3-(3,4,5-trimethoxyphenyl)propanehydrazide
tacrine-E2020 analog 7 BDBM8983 N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-{5H,10H-indeno[1,2-b]indol-10-ylamino}acetamide
tacrine-lipoic acid hybrid 8 BDBM10513 N-[(9-amino-6-chloro-1,2,3,4-tetrahydroacridin-3-yl)methyl]-5-(1,2-dithiolan-3-yl)pentanamide
BDBM10512 CHEMBL194823 tacrine-lipoic acid hybrid 7 N-{3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}-5-(1,2-dithiolan-3-yl)pentanamide
BDBM9428 N-(10-aminodecyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride CHEMBL1084092 N-9-(1,2,3,4-Tetrahydroacridinyl)-1,10-diaminodecane Bis-hydrochloride Heterodimeric Tacrine-Based Inhibitor 5i
BDBM9429 N-9-(1,2,3,4-Tetrahydroacridinyl)-1,12-diaminododecane Bis-hydrochloride Heterodimeric Tacrine-Based Inhibitor 5k CHEMBL1084093 N-(12-aminododecyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride
N-9-(1,2,3,4-Tetrahydroacridinyl)-1,7-diaminoheptane Bis-hydrochloride CHEMBL1083789 BDBM9425 Heterodimeric Tacrine-Based Inhibitor 5f N-(7-aminoheptyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride
BDBM8966 N,N-Bis[3-[(1,2,3,4-tetrahydroacridin-9-yl)amino]propyl]-N-ethylamine Tacrine Dimer 4b ethylbis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amine
BDBM9426 CHEMBL258928 N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octane Bis-hydrochloride N-(8-aminooctyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride Heterodimeric Tacrine-Based Inhibitor 5g
BDBM9427 N-(9-aminononyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride N-9-(1,2,3,4-Tetrahydroacridinyl)-1,9-diamino-nonane Bis-hydrochloride CHEMBL1083790 Heterodimeric Tacrine-Based Inhibitor 5h
11-Amino-1-chloro-6H-cyclohepta[b]quinoline 1-chloro-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine BDBM10487 Tacrine (THA) analogue 2
BDBM10514 N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propane-1,3-diamine CHEMBL191758 N-(3-aminopropyl)-6-chloro-1,2,3,4-tetrahydroacridin-9-amine tacrine (TC) deriv. 15
2-[6-(acridin-9-ylamino)hexyl]-2,3-dihydro-1H-isoindole-1,3-dione BDBM9070 2-[6-(Acridin-9-ylamino)-hexyl]-isoindole-1,3-dione Donepezil-tacrine hybrid 19
2-[9-(acridin-9-ylamino)nonyl]-2,3-dihydro-1H-isoindole-1,3-dione Donepezil-tacrine hybrid 22 2-[9-(Acridin-9-ylamino)-nonyl]-isoindole-1,3-dione BDBM9073
BDBM9071 2-[7-(acridin-9-ylamino)heptyl]-2,3-dihydro-1H-isoindole-1,3-dione Donepezil-tacrine hybrid 20 2-[7-(Acridin-9-ylamino)-heptyl]-isoindole-1,3-dione
BDBM9072 2-[8-(Acridin-9-ylamino)-octyl]-isoindole-1,3-dione 2-[8-(acridin-9-ylamino)octyl]-2,3-dihydro-1H-isoindole-1,3-dione Donepezil-tacrine hybrid 21
CHEMBL1084367 BDBM9433 dimethyl[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]amine dihydrochloride N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,10-diaminodecane Bis-hydrochloride Heterodimeric Tacrine-Based Inhibitor 6i
CHEMBL1084368 N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,12-diaminododecane Bis-hydrochloride dimethyl[12-(1,2,3,4-tetrahydroacridin-9-ylamino)dodecyl]amine dihydrochloride BDBM9434 Heterodimeric Tacrine-Based Inhibitor 6k
N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-diaminoheptane Hydrochloride Salt dimethyl[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amine trihydrochloride BDBM9430 Heterodimeric Tacrine-Based Inhibitor 6f CHEMBL1083791
N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane Bis-hydrochloride dimethyl[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]amine dihydrochloride CHEMBL1084094 BDBM9431 Heterodimeric Tacrine-Based Inhibitor 6g
N,N-Dimethyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9-diaminononane Bis-hydrochloride BDBM9432 CHEMBL1084095 Heterodimeric Tacrine-Based Inhibitor 6h dimethyl[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]amine dihydrochloride
2-{bis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amino}ethan-1-ol BDBM8968 N,N-Bis[3-[(1,2,3,4-tetrahydroacridin-9-yl)amino]propyl]-N-hydroxyethylamine Tacrine Dimer 4d
3,4,5-Trimethoxy-N-(2-oxo-2-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)ethyl)-benzamide BDBM13537 tacrine derivative 15b 3,4,5-trimethoxy-N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)methyl]benzamide
BDBM8967 prop-2-en-1-ylbis[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amine N,N-Bis[3-[(1,2,3,4-tetrahydroacridin-9-yl)amino]propyl]-N-allylamine Tacrine Dimer 4c
N-[12-(1,2,3,4-tetrahydroacridin-9-ylamino)dodecyl]pyridin-4-amine dihydrochloride BDBM9439 N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,12-diaminododecane Bis-hydrochloride Heterodimeric Tacrine-Based Inhibitor 7k
2-[7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptyl]-isoindole-1,3-dione 2-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-2,3-dihydro-1H-isoindole-1,3-dione Donepezil-tacrine hybrid 17 BDBM9068
2-[8-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-octyl]-isoindole-1,3-dione BDBM9069 2-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]-2,3-dihydro-1H-isoindole-1,3-dione Donepezil-tacrine hybrid 18
3,4,5-Trimethoxy-N-(5-oxo-5-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)pentyl)-benzamide tacrine derivative 15e 3,4,5-trimethoxy-N-[4-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)butyl]benzamide BDBM13540
3,4,5-trimethoxy-N-[8-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)octyl]benzamide 3,4,5-Trimethoxy-N-(9-oxo-9-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)nonyl)-benzamide BDBM13544 tacrine derivative 15i
BDBM13538 tacrine derivative 15c 3,4,5-Trimethoxy-N-(3-oxo-3-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)propyl)-benzamide 3,4,5-trimethoxy-N-[2-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)ethyl]benzamide
BDBM13539 tacrine derivative 15d 3,4,5-Trimethoxy-N-(4-oxo-4-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)butyl)-benzamide 3,4,5-trimethoxy-N-[3-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)propyl]benzamide
BDBM9437 CHEMBL1084530 N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]pyridin-4-amine dihydrochloride N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9-diaminononane Bis-hydrochloride Heterodimeric Tacrine-Based Inhibitor 7h
CHEMBL1084531 BDBM9438 N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,10-diaminodecane Bis-hydrochloride N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]pyridin-4-amine dihydrochloride Heterodimeric Tacrine-Based Inhibitor 7i
Heterodimeric Tacrine-Based Inhibitor 7f CHEMBL1084369 BDBM9435 N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-diaminoheptane Bis-hydrochloride N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]pyridin-4-amine dihydrochloride
Heterodimeric Tacrine-Based Inhibitor 8f CHEMBL1084775 N-4-Quinolyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,7-diaminoheptane Bis-hydrochloride BDBM9440 N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]quinolin-4-amine dihydrochloride
Heterodimeric Tacrine-Based Inhibitor 8g N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]quinolin-4-amine trihydrochloride N-4-Quinolyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane Hydrochloride Salt BDBM9441 CHEMBL1082738
N-4-Quinolyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,9-diaminononane Bis-hydrochloride N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]quinolin-4-amine dihydrochloride BDBM9442 CHEMBL1082739 Heterodimeric Tacrine-Based Inhibitor 8h
N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]pyridin-4-amine dihydrochloride BDBM9436 N-4-Pyridyl-N-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane Bis-hydrochloride CHEMBL1084096 Heterodimeric Tacrine-Based Inhibitor 7g
N-[9-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)nonyl]-1,2,3,4-tetrahydroacridin-9-amine Tacrine Dimer 4h BDBM8972 N-(1,2,3,4-Tetrahydroacridin-9-yl)-9-[(1,2,3,4-tetrahydro-9-yl)thio]nonan-1-amine
tacrine derivative 15f 3,4,5-trimethoxy-N-[5-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)pentyl]benzamide BDBM13541 3,4,5-Trimethoxy-N-(6-oxo-6-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)hexyl)-benzamide
tacrine derivative 15g 3,4,5-trimethoxy-N-[6-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)hexyl]benzamide BDBM13542 3,4,5-Trimethoxy-N-(7-oxo-7-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)heptyl)-benzamide
tacrine derivative 15h 3,4,5-trimethoxy-N-[7-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)heptyl]benzamide 3,4,5-Trimethoxy-N-(8-oxo-8-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)octyl)-benzamide BDBM13543
N-(1,2,3,4-Tetrahydroacridin-9-yl)-N-[8-(1,2,3,4-tetrahydroacridin-9-yl)oct-1-yl]amine Tacrine Dimer 4i BDBM8973 N-[8-(1,2,3,4-tetrahydroacridin-9-yl)octyl]-1,2,3,4-tetrahydroacridin-9-amine
N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)methyl]-3-(3,4,5-trimethoxyphenyl)propanamide tacrine derivative 16b BDBM13546 3-(3,4,5-Trimethoxyphenyl)-N-(2-oxo-2-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-ethyl)propanamide
3-(3,4,5-Trimethoxyphenyl)-N-(4-oxo-4-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-butyl)propanamide tacrine derivative 16d BDBM13548 N-[3-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)propyl]-3-(3,4,5-trimethoxyphenyl)propanamide
BDBM13547 tacrine derivative 16c 3-(3,4,5-Trimethoxyphenyl)-N-(3-oxo-3-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-propyl)propanamide N-[2-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)ethyl]-3-(3,4,5-trimethoxyphenyl)propanamide
BDBM13549 tacrine derivative 16e 3-(3,4,5-Trimethoxyphenyl)-N-(5-oxo-5-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-pentyl)propanamide N-[4-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)butyl]-3-(3,4,5-trimethoxyphenyl)propanamide
tacrine derivative 16f N-[5-(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)pentyl]-3-(3,4,5-trimethoxyphenyl)propanamide 3-(3,4,5-Trimethoxyphenyl)-N-(6-oxo-6-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-hexyl)propanamide BDBM13550
3-(1H-Indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-9-yl-amino)pentyl]propionamide Indole-Tacrine Heterodimer 3 3-(1H-indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]propanamide BDBM9020
1H-Indazole-3-carboxylic Acid [7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amide N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1H-indazole-3-carboxamide Indazole-Tacrine Heterodimer 23 BDBM9040
1H-Indole-3-carboxylic Acid [6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]amide Indole-Tacrine Heterodimer 15 BDBM9032 N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-1H-indole-3-carboxamide
1H-Indole-3-carboxylic Acid [7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amide BDBM9033 Indole-Tacrine Heterodimer 16 N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1H-indole-3-carboxamide
1H-Indole-3-carboxylic Acid [8-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)octyl]amide N-{8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}-1H-indole-3-carboxamide BDBM9034 Indole-Tacrine Heterodimer 17
6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(1H-indol-3-yl)-ethyl]-amide BDBM9006 N-[2-(1H-indol-3-yl)ethyl]-6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexanamide Tacrine-Melatonin Hybrid 3a
BDBM9007 7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-3-yl)-ethyl]-amide Tacrine-Melatonin Hybrid 3b N-[2-(1H-indol-3-yl)ethyl]-7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptanamide
Indole-Tacrine Heterodimer 14 1H-Indole-3-carboxylic Acid [5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]amide N-{5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl}-1H-indole-3-carboxamide BDBM9031
2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]amino}methyl)-1H-indene-1,3(2H)-dione Donepezil-tacrine hybrid 9 2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]amino}methyl)-2,3-dihydro-1H-indene-1,3-dione BDBM9064
1,1,1-trifluoro-7-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylamino)heptane-2,2-diol N-Alkylated Tacrine Analogue 6b BDBM10491 7-{6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-ylamino}-1,1,1-trifluoroheptane-2,2-diol
BDBM8976 methyl[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl][4-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)butyl]amine Tacrine Dimer 4l CHEMBL175555 N-Methyl-N-(1,2,3,4-tetrahydroacridin-9-yl)-N-[4-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)butyl]-1,3-propanediamine
BDBM9039 Indole-Tacrine Heterodimer 22 N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-1-methyl-1H-indole-3-carboxamide 1H-Methylindole-3-carboxylic Acid [7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amide
Tacrine Dimer 4j CHEMBL367067 BDBM8974 N-Methyl-N-(1,2,3,4-tetrahydroacridin-9-yl)-N-[3-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)propyl]-1,3-propanediamine methyl[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl][3-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)propyl]amine
1-chloro-N-(thiophen-2-ylmethyl)-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine BDBM10488 1-chloro-N-(thien-2-ylmethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine N-Alkylated Tacrine Analogue 3
5,6-Dimethoxy-2-{[6-(1,2,3,4-tetrahydro-acridin-9-ylamino)-hexylamino]-methyl}-indan-1-one 5,6-dimethoxy-2-({[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]amino}methyl)-2,3-dihydro-1H-inden-1-one Donepezil-tacrine hybrid 7 BDBM9062
BDBM9037 N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-pentyl]-4-(1H-indol-3-yl)butyramide Indole-Tacrine Heterodimer 20 N-{5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl}-4-(1H-indol-3-yl)butanamide
Indole-Tacrine Heterodimer 21 BDBM9038 N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-4-(1H-indol-3-yl)butyramide N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-4-(1H-indol-3-yl)butanamide
N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-pentyl]-3-(1H-indol-3-yl)propionamide Indole-Tacrine Heterodimer 4 N-{5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl}-3-(1H-indol-3-yl)propanamide BDBM9021
N-[9-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-nonyl]-3-(1H-indol-3-yl)propionamide N-{9-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]nonyl}-3-(1H-indol-3-yl)propanamide Indole-Tacrine Heterodimer 8 BDBM9025
N-{10-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]decyl}-3-(1H-indol-3-yl)propanamide BDBM9026 N-[10-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-decyl]-3-(1H-indol-3-yl)propionamide Indole-Tacrine Heterodimer 9
N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-2-(1H-indol-3-yl)acetamide BDBM9035 N-[7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-heptyl]-2-(1H-indol-3-yl)acetamide Indole-Tacrine Heterodimer 18
N-{8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}-3-(1H-indol-3-yl)propanamide Indole-Tacrine Heterodimer 7 BDBM9024 N-[8-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-octyl]-3-(1H-indol-3-yl)propionamide
6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(5-hydroxy-1H-indol-3-yl)-ethyl]-amide Tacrine-Melatonin Hybrid 11a BDBM9018 N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexanamide
CHEMBL484306 5,6-dimethoxy-2-({[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amino}methyl)-2,3-dihydro-1H-inden-1-one 5,6-Dimethoxy-2-{[7-(1,2,3,4-tetrahydro-acridin-9-ylamino)-heptylamino]-methyl}-indan-1-one Donepezil-tacrine hybrid 8 BDBM9063
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptanamide 7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-5-metoxy-3-yl)-ethyl]-amide Tacrine-Melatonin Hybrid 7b BDBM9014
N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-3-(1H-indol-3-yl)propanamide BDBM9022 Indole-Tacrine Heterodimer 5 CHEMBL225567 N-[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-3-(1H-indol-3-yl)propionamide
N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-3-(1H-indol-3-yl)propanamide Indole-Tacrine Heterodimer 6 CHEMBL225198 BDBM9023 N-[7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-heptyl]-3-(1H-indol-3-yl)propionamide
Tacrine-Melatonin Hybrid 7a BDBM9013 N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexanamide 6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide
6-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]hexanamide BDBM9011 6-(6,8-Dichloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(1H-indol-3-yl)-ethyl]-amide Tacrine-Melatonin Hybrid 6a
BDBM9008 6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(1H-indol-3-yl)-ethyl]-amide 6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]hexanamide Tacrine-Melatonin Hybrid 4a
BDBM9009 7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]heptanamide Tacrine-Melatonin Hybrid 4b 7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-3-yl)-ethyl]-amide
Homodimeric Tacrine Analog 2b N-(7-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}heptyl)-1H,2H,3H-cyclopenta[b]quinolin-9-amine N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-8-yl)-1,7-diaminoheptane BDBM9045
Homodimeric Tacrine Analog 2c N-(8-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}octyl)-1H,2H,3H-cyclopenta[b]quinolin-9-amine BDBM9046 N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-8-yl)-1,8-diaminooctane
N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-8-yl)-1,6-diaminohexane Homodimeric Tacrine Analog 2a N-(6-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}hexyl)-1H,2H,3H-cyclopenta[b]quinolin-9-amine BDBM9044
N-(3-{[3-(1,2,3,4-Tetrahydroacridin-9-ylamino)propyl]-methylamino}propyl)-3-(1H-indol-3-yl)propionamide Indole-Tacrine Heterodimer 10 BDBM9027 3-(1H-indol-3-yl)-N-(3-{methyl[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amino}propyl)propanamide
Tacrine-Melatonin Hybrid 5a 6-(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(1H-indol-3-yl)-ethyl]-amide 6-[(8-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]hexanamide BDBM9010
2-(1H-indol-3-yl)ethyl N-{5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl}carbamate Indole-Tacrine Heterodimer 27 BDBM9041 [5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-pentyl]carbamic Acid 2-(1H-Indol-3-yl)ethyl Ester
2-(1H-indol-3-yl)ethyl N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}carbamate Indole-Tacrine Heterodimer 29 BDBM9043 [7-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-heptyl]carbamic Acid 2-(1H-Indol-3-yl)ethyl Ester
7-(6,8-Dichloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-3-yl)-ethyl]-amide BDBM9012 Tacrine-Melatonin Hybrid 6b CHEMBL199585 7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]heptanamide
Indole-Tacrine Heterodimer 13 N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-3-(1H-indol-3-yl)acrylamide (2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-3-(1H-indol-3-yl)prop-2-enamide BDBM9030
[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]-carbamic Acid 2-(1H-Indol-3-yl)ethyl Ester 2-(1H-indol-3-yl)ethyl N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}carbamate Indole-Tacrine Heterodimer 28 BDBM9042
2-(5-Bromo-1H-indol-3-yl)-N-[7-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]acetamide 2-(5-bromo-1H-indol-3-yl)-N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}acetamide BDBM9036 Indole-Tacrine Heterodimer 19
BDBM10490 N-Alkylated Tacrine Analogue 6a 7-[(1-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)amino]-1,1,1-trifluoroheptane-2,2-diol 7-({1-chloro-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-yl}amino)-1,1,1-trifluoroheptane-2,2-diol
BDBM9017 Tacrine-Melatonin Hybrid 10b 7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]heptanamide 7-(6,8-Dichloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(5-methoxy-1Hindol-3-yl)-ethyl]-amide
N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-3-(5-cyano-1H-indol-3-yl)propanamide Indole-Tacrine Heterodimer 12 BDBM9029 N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-3-(5-cyano-1H-indol-3-yl)propionamide
6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide BDBM9015 6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]hexanamide Tacrine-Melatonin Hybrid 8a
BDBM9016 Tacrine-Melatonin Hybrid 9a 6-(8-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide 6-[(8-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]hexanamide
BDBM9059 N,N-Bis-(2,3,4,5-tetrahydro-1H-cyclohepta[1,2,-b]quinolin-10-yl)-1,6-diaminohexane N-(6-{6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-ylamino}hexyl)-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine Homodimeric Tacrine Analog 4a
BDBM9060 Homodimeric Tacrine Analog 4b N,N-Bis-(2,3,4,5-tetrahydro-1H-cyclohepta[1,2,-b]quinolin-10-yl)-1,7-diaminoheptane N-(7-{6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-ylamino}heptyl)-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine
BDBM9061 Homodimeric Tacrine Analog 4c N,N-Bis-(2,3,4,5-tetrahydro-1H-cyclohepta[1,2,-b]quinolin-10-yl)-1,8-diaminooctane N-(8-{6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-ylamino}octyl)-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine
N-(3-{[3-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-propyl]methylamino}propyl)-3-(1H-indol-3-yl)propionamide BDBM9028 N-[3-({3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}(methyl)amino)propyl]-3-(1H-indol-3-yl)propanamide Indole-Tacrine Heterodimer 11
N-[7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-heptyl]-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)acetamide N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetamide Donepezil-tacrine hybrid 11 BDBM9066
N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetamide Donepezil-tacrine hybrid 10 N-[6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-hexyl]-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)acetamide BDBM9065
(9E)-N1-(7-(1,2,3,4-Tetrahydroacridin-9-ylamino)heptyl)-9-ethylidene-7-methylbicyclo[3.3.1]non-6-ene-1,3-diamine Huperzine A-Tacrine Hybrid 5b BDBM10594 N-(7-{[(1S)-1-amino-9-ethylidene-7-methylbicyclo[3.3.1]non-6-en-3-yl]amino}heptyl)-1,2,3,4-tetrahydroacridin-9-amine
Huperzine A-Tacrine Hybrid 5a N-(7-{[(1S)-1-amino-9-ethylidene-4,4,7-trimethylbicyclo[3.3.1]non-6-en-3-yl]amino}heptyl)-1,2,3,4-tetrahydroacridin-9-amine BDBM10593 (9E)-N1-(7-(1,2,3,4-Tetrahydroacridin-9-ylamino)heptyl)-9-ethylidene-4,4,7-trimethylbicyclo[3.3.1]non-6-ene-1,3-diamine
N,N-Bis-(1,2,3,4-tetrahydro-cyclohexa[1,2,-b]pyrido-[2,3-b]pyrid-9-yl)-1,6-diaminohexane BDBM9056 Homodimeric Tacrine Analog 3j N-(6-{6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-ylamino}hexyl)-6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-amine
N,N-Bis-(1,2,3,4-tetrahydro-cyclohexa[1,2,-b]pyrido-[2,3-b]pyrid-9-yl)-1,7-di-aminoheptane N-(7-{6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-ylamino}heptyl)-6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-amine Homodimeric Tacrine Analog 3k BDBM9057
N-(8-{6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-ylamino}octyl)-6H,7H,8H,9H-cyclohexa[b]1,8-naphthyridin-5-amine BDBM9058 N,N-Bis-(1,2,3,4-tetrahydro-cyclohexa[1,2,-b]pyrido-[2,3-b]pyrid-9-yl)-1,8-di-aminooctane Homodimeric Tacrine Analog 3m
15-ethyl-N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride 9-Ethyl-6,7,10,11-tetrahydro-12-{{8-[(1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride Huprine-Tacrine Heterodimer 12 BDBM10582
methyl (1S)-9-ethylidene-3-methyl-7-{[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]amino}bicyclo[3.3.1]non-3-ene-1-carboxylate Huperzine A-Tacrine Hybrid 5c BDBM10595 (9E)-7-(7-(1,2,3,4-Tetrahydroacridin-9-ylamino)heptylamino)-9-ethylidene-3-methylbicyclo[3.3.1]non-3-ene-1-carboxylic Acid Methyl Ester
BDBM10489 1-{5-[({1-chloro-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-yl}amino)methyl]thiophen-2-yl}-2,2,2-trifluoroethan-1-one N-Alkylated Tacrine Analogue 4 1-(5-{[(1-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)amino]methyl}thien-2-yl)-2,2,2-trifluoroethanone
3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{6-[(1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride 7-chloro-15-methyl-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride BDBM10583 Huprine-Tacrine Heterodimer 17a CHEMBL2011483
3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{7-[(1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride 7-chloro-15-methyl-N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride Huprine-Tacrine Heterodimer 17b BDBM10584 CHEMBL2011484
7-chloro-15-methyl-N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride BDBM10585 3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride Huprine-Tacrine Heterodimer 17c CHEMBL2011488
N-{4-[{2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}(methyl)amino]butyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide Donepezil-tacrine hybrid 12 BDBM9067 N-[4-({2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}(methyl)amino)butyl]-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetamide
3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride 7-chloro-N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride BDBM10588 Huprine-Tacrine Heterodimer 18b CHEMBL2011492
3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride BDBM10589 CHEMBL2011496 Huprine-Tacrine Heterodimer 18c 7-chloro-N-{8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl}-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride
CHEMBL2011491 BDBM10587 3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}amino}-7,11-methanocycloocta[b]quinoline dihydrochloride Huprine-Tacrine Heterodimer 18a 7-chloro-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine dihydrochloride
Huprine-Tacrine Heterodimer 17d 3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{3-{N-{3-[(1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}-N-methylamino}propyl}amino}-7,11-methanocycloocta[b]quinoline trihydrochloride BDBM10586 CHEMBL2011487 [3-({7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-yl}amino)propyl](methyl)[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amine trihydrochloride
3-Chloro-6,7,10,11-tetrahydro-9-methyl-12-{{3-{N-{3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}-N-methylamino}propyl}amino}-7,11-methanocycloocta[b]quinoline trihydrochloride Huprine-Tacrine Heterodimer 18d BDBM10590 CHEMBL2011495 {3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}[3-({7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11}.0^{4,9}]heptadeca-2(11),3,5,7,9,14-hexaen-3-yl}amino)propyl]methylamine trihydrochloride