BDBM58373 cid_21966304 SMR000499571 MLS001076663 Vancomycin hydrochloride hydrate
Vancoled Viomycin derivative Vancocin N-demethylvancomycin derivative Poly ethylene glycol derivative Glycopeptide antibiotic Mannopeptimycin glycopeptide analogue Vancor Chloroorienticin B derivative Tuberactinomycin Analogue (S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-((S)-6-hydroxy-2-imino-hexahydro-pyrimidin-4-yl)-9,12-bis-hydroxymethyl-2,5,8,11,14-pentaoxo-6-[1-ureido-meth-(Z)-ylidene]-1,4,7,10,13pentaaza-cyclohexadec-15-yl}-amide Mannopeptimycin Glycopeptide BDBM50335519 vancomycin CHEMBL262777 4-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole vanomycin
- Ni, S; Wei, H; Li, B; Chen, F; Liu, Y; Chen, W; Xu, Y; Qiu, X; Li, X; Lu, Y; Liu, W; Hu, L; Lin, D; Wang, M; Zheng, X; Mao, F; Zhu, J; Lan, L; Li, J Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo. J Med Chem 60: 8145-8159 (2017)
- Muthyala, R; Rastogi, N; Shin, WS; Peterson, ML; Sham, YY Cell permeable vanX inhibitors as vancomycin re-sensitizing agents. Bioorg Med Chem Lett 24: 2535-8 (2014)
- Kaur, J; Cao, X; Abutaleb, NS; Elkashif, A; Graboski, AL; Krabill, AD; AbdelKhalek, AH; An, W; Bhardwaj, A; Seleem, MN; Flaherty, DP Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant J Med Chem 63: 9540-9562 (2020)
- Hill, CM; Krause, KM; Lewis, SR; Blais, J; Benton, BM; Mammen, M; Humphrey, PP; Kinana, A; Janc, JW Specificity of induction of the vanA and vanB operons in vancomycin-resistant enterococci by telavancin. Antimicrob Agents Chemother 54: 2814-8 (2010)
- Geib, N; Woithe, K; Zerbe, K; Li, DB; Robinson, JA New insights into the first oxidative phenol coupling reaction during vancomycin biosynthesis. Bioorg Med Chem Lett 18: 3081-4 (2008)
- Vermote, A; Brackman, G; Risseeuw, MD; Cappoen, D; Cos, P; Coenye, T; Van Calenbergh, S Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach. ACS Med Chem Lett 8: 38-42 (2017)
- de Souza, NJ; Gupte, SV; Deshpande, PK; Desai, VN; Bhawsar, SB; Yeole, RD; Shukla, MC; Strahilevitz, J; Hooper, DC; Bozdogan, B; Appelbaum, PC; Jacobs, MR; Shetty, N; Patel, MV; Jha, R; Khorakiwala, HF A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus. J Med Chem 48: 5232-42 (2005)
- Durcik, M; Cotman, AE; Toplak, ?; Mo?ina, ?; Skok, ?; Szili, PE; Czikkely, M; Maharramov, E; Vu, TH; Piras, MV; Zidar, N; Ila?, J; Zega, A; Trontelj, J; Pardo, LA; Hughes, D; Huseby, D; Berruga-Fernández, T; Cao, S; Simoff, I; Svensson, R; Korol, SV; Jin, Z; Vicente, F; Ramos, MC; Mundy, JEA; Maxwell, A; Stevenson, CEM; Lawson, DM; Glinghammar, B; Sjöström, E; Bohlin, M; Oreskär, J; Alvér, S; Janssen, GV; Sterk, GJ; Kikelj, D; Pal, C; Toma?i?, T; Peterlin Ma?i?, L New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate J Med Chem 66: 3968-3994 (2023)
- Wei, H; Mao, F; Ni, S; Chen, F; Li, B; Qiu, X; Hu, L; Wang, M; Zheng, X; Zhu, J; Lan, L; Li, J Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections. Eur J Med Chem 145: 235-251 (2018)
- ChEBML_1692280 Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated with vancomycin for 24 hrs
- ChEMBL_1692280 (CHEMBL4042929) Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated with vancomycin for 24 hrs
- ChEMBL_1692279 (CHEMBL4042928) Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4 hrs prior to vancomycin addition measured after 20 hrs
- ChEMBL_1707101 (CHEMBL4058334) Antimicrobial activity against vancomycin-resistant Enterococcus faecalis NCTC12201 after 8 hrs
- ChEMBL_1541901 (CHEMBL3743168) Antibacterial activity against low level vancomycin-resistant Enterococcus faecalis ATCC 51299 by plate reader analysis
- ChEMBL_1337535 (CHEMBL3242294) Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution method
- ChEMBL_1337536 (CHEMBL3242295) Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth microdilution method
- ChEMBL_1337537 (CHEMBL3242296) Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution method
- ChEMBL_1337538 (CHEMBL3242297) Antibacterial activity against vancomycin-resistant Enterococcus faecalis 09-9 after 18 hrs by broth microdilution method
- ChEMBL_525780 (CHEMBL969144) Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assay
- ChEMBL_671925 (CHEMBL1266964) Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assay
- ChEMBL_671927 (CHEMBL1267048) Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding assay
- ChEMBL_671924 (CHEMBL1266963) Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by competitive binding assay
- ChEMBL_671926 (CHEMBL1266965) Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competitive binding assay
- ChEMBL_671928 (CHEMBL1267049) Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by competitive binding assay
- ChEMBL_1784288 (CHEMBL4255805) Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay
- ChEMBL_1837923 (CHEMBL4338056) Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs by spectrophotometry based broth microdilution assay