Compound (1)
Article Title (7)
Assay (4)
Huang, M; Xie, X; Gong, P; Wei, Y; Du, H; Xu, Y; Xu, Q; Jing, Y; Zhao, L A 18?-glycyrrhetinic acid conjugate with Vorinostat degrades HDAC3 and HDAC6 with improved antitumor effects. Eur J Med Chem 188: (2020) Chu-Farseeva, YY; Mustafa, N; Poulsen, A; Tan, EC; Yen, JJY; Chng, WJ; Dymock, BW Design and synthesis of potent dual inhibitors of JAK2 and HDAC based on fusing the pharmacophores of XL019 and vorinostat. Eur J Med Chem 158: 593 -619 (2018) Erdeljac, N; Bussmann, K; Sch?ler, A; Hansen, FK; Gilmour, R Fluorinated Analogues of the Histone Deacetylase Inhibitor Vorinostat (Zolinza): Validation of a Chiral Hybrid Bioisostere, BITE. ACS Med Chem Lett 10: 1336 -1340 (2019) Yao, L; Ramanujulu, PM; Poulsen, A; Ohlson, S; Dymock, BW Merging of ruxolitinib and vorinostat leads to highly potent inhibitors of JAK2 and histone deacetylase 6 (HDAC6). Bioorg Med Chem Lett 28: 2636 -2640 (2018) Hanessian, S; Auzzas, L; Giannini, G; Marzi, M; Cabri, W; Barbarino, M; Vesci, L; Pisano, C Omega-alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: a study of chain-length and stereochemical dependence. Bioorg Med Chem Lett 17: 6261 -5 (2007) Yao, L; Mustafa, N; Tan, EC; Poulsen, A; Singh, P; Duong-Thi, MD; Lee, JXT; Ramanujulu, PM; Chng, WJ; Yen, JJY; Ohlson, S; Dymock, BW Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat. J Med Chem 60: 8336 -8357 (2017) Cai, J; Wei, H; Hong, KH; Wu, X; Zong, X; Cao, M; Wang, P; Li, L; Sun, C; Chen, B; Zhou, G; Chen, J; Ji, M Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents. Bioorg Med Chem 23: 3457 -71 (2015)
SAHA US11505523, Compound SAHA US9353061, SAHA BDBM19149 cid_5311 suberoylanilide hydroxamic acid N-hydroxy-N'-phenyloctanediamide US10011611, SAHA US9428447, SAHA US9695181, Vorinostat US10188756, Compound SAHA US11207431, SAHA Vorinostat US9115116, SAHA CHEMBL98 Zolinza