BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 192520 COc1ccc2nc(NC(=O)CSc3nc4cccnc4n3C)sc2c1 InChI=1S/C17H15N5O2S2/c1-22-15-12(4-3-7-18-15)20-17(22)25-9-14(23)21-16-19-11-6-5-10(24-2)8-13(11)26-16/h3-8H,9H2,1-2H3,(H,19,21,23) NGLUSXHDTJGONE-UHFFFAOYSA-N 39325 SMR000005802::N-(6-Methoxy-benzothiazol-2-yl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)-acetamide::cid_645553::N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(3-methylimidazo[4,5-b]pyridin-2-yl)sulfanyl-ethanamide::N-(6-methoxy-1,3-benzothiazol-2-yl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide::MLS000072990::N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(3-methylimidazo[4,5-b]pyridin-2-yl)sulfanylacetamide::N-(6-methoxy-1,3-benzothiazol-2-yl)-2-[(3-methylimidazo[4,5-b]pyridin-2-yl)thio]acetamide Melanocortin receptor 4 Homo sapiens >89173 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39325 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39325&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 645553 252620220 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192521 Cc1cc(N2CCN(CC2)C(=O)c2ccco2)n2nc(cc2n1)-c1cccc(Cl)c1 InChI=1S/C22H20ClN5O2/c1-15-12-21(26-7-9-27(10-8-26)22(29)19-6-3-11-30-19)28-20(24-15)14-18(25-28)16-4-2-5-17(23)13-16/h2-6,11-14H,7-10H2,1H3 KCGMIJAMMIIVFQ-UHFFFAOYSA-N 38296 [4-[2-(3-chlorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]piperazin-1-yl]-(furan-2-yl)methanone::[4-[2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]piperazin-1-yl]-(furan-2-yl)methanone::{4-[2-(3-Chloro-phenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]-piperazin-1-yl}-furan-2-yl-methanone::SMR000007919::cid_652994::MLS000076302::[4-[2-(3-chlorophenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanone::[4-[2-(3-chlorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]piperazino]-(2-furyl)methanone Melanocortin receptor 4 Homo sapiens >89167 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38296 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38296&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 652994 252619214 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192522 CCC(C)NC(=O)c1c(N)n(\N=C\c2cccnc2)c2nc3ccccc3nc12 InChI=1S/C21H21N7O/c1-3-13(2)25-21(29)17-18-20(27-16-9-5-4-8-15(16)26-18)28(19(17)22)24-12-14-7-6-10-23-11-14/h4-13H,3,22H2,1-2H3,(H,25,29) QIRNGGUFFRZXIW-UHFFFAOYSA-N 88420 2-amino-N-butan-2-yl-1-[(E)-3-pyridinylmethylideneamino]-3-pyrrolo[3,2-b]quinoxalinecarboxamide::SMR000043624::2-amino-N-butan-2-yl-1-[(E)-pyridin-3-ylmethylideneamino]pyrrolo[3,2-b]quinoxaline-3-carboxamide::cid_9568667::MLS000040301::2-azanyl-N-butan-2-yl-1-[(E)-pyridin-3-ylmethylideneamino]pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-amino-1-[(E)-3-pyridylmethyleneamino]-N-sec-butyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide Melanocortin receptor 4 Homo sapiens >89174 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88420&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9568667 252660136 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192523 O=C(COc1ccc2OCOc2c1)Nc1ccc2c(c1)oc1ccccc21 InChI=1S/C21H15NO5/c23-21(11-24-14-6-8-18-20(10-14)26-12-25-18)22-13-5-7-16-15-3-1-2-4-17(15)27-19(16)9-13/h1-10H,11-12H2,(H,22,23) CAUAVVKSMDXLGF-UHFFFAOYSA-N 88421 cid_2944700::SMR000074017::MLS000096734::2-(1,3-benzodioxol-5-yloxy)-N-dibenzofuran-3-ylacetamide::2-(1,3-benzodioxol-5-yloxy)-N-dibenzo[b,d]furan-3-ylacetamide::2-(1,3-benzodioxol-5-yloxy)-N-dibenzofuran-3-yl-ethanamide::2-(1,3-benzodioxol-5-yloxy)-N-(3-dibenzofuranyl)acetamide::2-(1,3-benzodioxol-5-yloxy)-N-dibenzofuran-3-yl-acetamide Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88421 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88421&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2944700 252660137 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192524 CCSc1nnc(NC(=O)c2csc3CCCCc23)s1 InChI=1S/C13H15N3OS3/c1-2-18-13-16-15-12(20-13)14-11(17)9-7-19-10-6-4-3-5-8(9)10/h7H,2-6H2,1H3,(H,14,15,17) CTZQTQYATIIITQ-UHFFFAOYSA-N 88422 N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::cid_1247777::SMR000080833::N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::MLS000099834::N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide Melanocortin receptor 4 Homo sapiens >89203 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88422 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88422&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1247777 252660138 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192525 Cc1cc(C)n(n1)-c1nc2cc(C)ccc2nc1Nc1ccc2[nH]c(=O)[nH]c2c1 InChI=1S/C21H19N7O/c1-11-4-6-15-17(8-11)24-20(28-13(3)9-12(2)27-28)19(23-15)22-14-5-7-16-18(10-14)26-21(29)25-16/h4-10H,1-3H3,(H,22,23)(H2,25,26,29) PXYWXGIMQSDKDV-UHFFFAOYSA-N 39556 5-[[3-(3,5-dimethyl-1-pyrazolyl)-6-methyl-2-quinoxalinyl]amino]-1,3-dihydrobenzimidazol-2-one::cid_1253520::5-[[3-(3,5-dimethylpyrazol-1-yl)-6-methylquinoxalin-2-yl]amino]-1,3-dihydrobenzimidazol-2-one::MLS000052231::5-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-2-quinoxalinyl]amino}-1,3-dihydro-2H-benzimidazol-2-one::SMR000081644::5-[[3-(3,5-dimethylpyrazol-1-yl)-6-methyl-quinoxalin-2-yl]amino]-1,3-dihydrobenzimidazol-2-one Melanocortin receptor 4 Homo sapiens >89219 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39556 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39556&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1253520 252620447 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192526 COc1cc(cc(OC)c1OC)C(=O)Nc1nnc(s1)-c1sccc1C InChI=1S/C17H17N3O4S2/c1-9-5-6-25-14(9)16-19-20-17(26-16)18-15(21)10-7-11(22-2)13(24-4)12(8-10)23-3/h5-8H,1-4H3,(H,18,20,21) CEZVEQQXQOXVFD-UHFFFAOYSA-N 40529 3,4,5-trimethoxy-N-[5-(3-methyl-2-thiophenyl)-1,3,4-thiadiazol-2-yl]benzamide::SMR000075115::cid_2948917::MLS000049290::3,4,5-trimethoxy-N-[5-(3-methylthiophen-2-yl)-1,3,4-thiadiazol-2-yl]benzamide::3,4,5-trimethoxy-N-[5-(3-methyl-2-thienyl)-1,3,4-thiadiazol-2-yl]benzamide Melanocortin receptor 4 Homo sapiens >89206 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40529 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40529&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2948917 252621351 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192527 CCc1ccc(cc1)C1CC(Nc2nc(N)nn12)c1ccc(F)cc1 InChI=1S/C19H20FN5/c1-2-12-3-5-14(6-4-12)17-11-16(13-7-9-15(20)10-8-13)22-19-23-18(21)24-25(17)19/h3-10,16-17H,2,11H2,1H3,(H3,21,22,23,24) QNTXKYZDYHUOTN-UHFFFAOYSA-N 88423 cid_5307804::SMR000092238::7-(4-ethylphenyl)-5-(4-fluorophenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine::MLS000114968::[7-(4-ethylphenyl)-5-(4-fluorophenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]amine Melanocortin receptor 4 Homo sapiens 48070 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88423 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88423&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5307804 252660139 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192528 CCn1cc(\C=C2\CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C2=O)c(C)n1 |t:11| InChI=1S/C26H36N2O2/c1-5-28-15-18(16(2)27-28)12-17-13-23-21-7-6-19-14-20(29)8-10-25(19,3)22(21)9-11-26(23,4)24(17)30/h6,12,15,20-23,29H,5,7-11,13-14H2,1-4H3 IKSAIBRTZFZGMG-UHFFFAOYSA-N 88424 16-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)methylene]-3-hydroxyandrost-5-en-17-one::(16Z)-16-[(1-ethyl-3-methyl-4-pyrazolyl)methylidene]-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one::cid_9549133::(16Z)-16-[(1-ethyl-3-methyl-pyrazol-4-yl)methylidene]-10,13-dimethyl-3-oxidanyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one::SMR000114956::(16Z)-16-[(1-ethyl-3-methylpyrazol-4-yl)methylidene]-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one::MLS000594607::(16Z)-16-[(1-ethyl-3-methyl-pyrazol-4-yl)methylene]-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one Melanocortin receptor 4 Homo sapiens >89183 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88424 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88424&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9549133 252660140 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192529 CCOc1cc(NC(=O)c2cccs2)c(OCC)cc1NC(=O)c1ccco1 InChI=1S/C20H20N2O5S/c1-3-25-16-12-14(22-20(24)18-8-6-10-28-18)17(26-4-2)11-13(16)21-19(23)15-7-5-9-27-15/h5-12H,3-4H2,1-2H3,(H,21,23)(H,22,24) AGWFGPCZMMBBOZ-UHFFFAOYSA-N 48458 N-[2,5-diethoxy-4-[[oxo(thiophen-2-yl)methyl]amino]phenyl]-2-furancarboxamide::SMR000120603::Furan-2-carboxylic acid {2,5-diethoxy-4-[(thiophene-2-carbonyl)-amino]-phenyl}-amide::cid_1374340::N-[2,5-diethoxy-4-(thiophen-2-ylcarbonylamino)phenyl]furan-2-carboxamide::N-[2,5-diethoxy-4-(thiophene-2-carbonylamino)phenyl]furan-2-carboxamide::MLS000528029::N-[2,5-diethoxy-4-(2-thenoylamino)phenyl]-2-furamide Melanocortin receptor 4 Homo sapiens >89061 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48458&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1374340 252628751 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192530 Cc1ccc(cc1)C(=O)c1coc-2c1C(=O)C(=O)c1ccccc-21 InChI=1S/C20H12O4/c1-11-6-8-12(9-7-11)17(21)15-10-24-20-14-5-3-2-4-13(14)18(22)19(23)16(15)20/h2-10H,1H3 OOYQRVPZOGWCNP-UHFFFAOYSA-N 34677 3-(4-methylphenyl)carbonylbenzo[g][1]benzofuran-4,5-dione::cid_1736341::3-(4-methylbenzoyl)benzo[g][1]benzofuran-4,5-dione::3-(4-methylbenzoyl)naphtho[1,2-b]furan-4,5-dione::SMR000137097::MLS000532156::3-[(4-methylphenyl)-oxomethyl]benzo[g]benzofuran-4,5-dione::3-p-toluoylbenzo[g]benzofuran-4,5-quinone Melanocortin receptor 4 Homo sapiens >89179 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34677 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34677&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1736341 252617327 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192531 CCOCCCN(Cc1ccco1)C(=O)c1cc2c(s1)c1cc(C)ccc1[nH]c2=O InChI=1S/C23H24N2O4S/c1-3-28-10-5-9-25(14-16-6-4-11-29-16)23(27)20-13-18-21(30-20)17-12-15(2)7-8-19(17)24-22(18)26/h4,6-8,11-13H,3,5,9-10,14H2,1-2H3,(H,24,26) XKFIIQRBGZOBEQ-UHFFFAOYSA-N 88425 N-(3-ethoxypropyl)-N-(2-furanylmethyl)-8-methyl-4-oxo-5H-thieno[3,2-c]quinoline-2-carboxamide::cid_9550523::SMR000128320::MLS000523054::N-(3-ethoxypropyl)-N-(furan-2-ylmethyl)-8-methyl-4-oxidanylidene-5H-thieno[3,2-c]quinoline-2-carboxamide::N-(3-ethoxypropyl)-N-(furan-2-ylmethyl)-8-methyl-4-oxo-5H-thieno[3,2-c]quinoline-2-carboxamide::N-(3-ethoxypropyl)-N-(2-furfuryl)-4-keto-8-methyl-5H-thieno[3,2-c]quinoline-2-carboxamide Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88425 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88425&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9550523 252660141 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192532 Cc1ccccc1-c1nc(no1)-c1ccc(NC(=O)c2ccc(Br)o2)cc1 InChI=1S/C20H14BrN3O3/c1-12-4-2-3-5-15(12)20-23-18(24-27-20)13-6-8-14(9-7-13)22-19(25)16-10-11-17(21)26-16/h2-11H,1H3,(H,22,25) OBPNRGGUFSHYKJ-UHFFFAOYSA-N 88426 cid_5070905::5-bromanyl-N-[4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]furan-2-carboxamide::5-bromo-N-[4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-furancarboxamide::MLS000521292::5-bromo-N-[4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]furan-2-carboxamide::SMR000131700::5-bromo-N-[4-[5-(o-tolyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-furamide Melanocortin receptor 4 Homo sapiens >89224 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88426 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88426&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5070905 252660142 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192533 Cc1ccccc1-c1nc(no1)-c1ccc(NC(=O)c2ccc3OCOc3c2)cc1 InChI=1S/C23H17N3O4/c1-14-4-2-3-5-18(14)23-25-21(26-30-23)15-6-9-17(10-7-15)24-22(27)16-8-11-19-20(12-16)29-13-28-19/h2-12H,13H2,1H3,(H,24,27) ARRJDAAWXQRBKY-UHFFFAOYSA-N 88427 MLS000536371::cid_1292146::N-[4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]-1,3-benzodioxole-5-carboxamide::SMR000143408::N-{4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}-1,3-benzodioxole-5-carboxamide::N-[4-[5-(o-tolyl)-1,2,4-oxadiazol-3-yl]phenyl]-piperonylamide Melanocortin receptor 4 Homo sapiens >89121 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88427 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88427&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1292146 252660143 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192534 CC(C)OCCCN(Cc1ccco1)C(=O)c1cc2c(s1)c1cc(C)ccc1[nH]c2=O InChI=1S/C24H26N2O4S/c1-15(2)29-11-5-9-26(14-17-6-4-10-30-17)24(28)21-13-19-22(31-21)18-12-16(3)7-8-20(18)25-23(19)27/h4,6-8,10,12-13,15H,5,9,11,14H2,1-3H3,(H,25,27) URIXKDVBEXJOBD-UHFFFAOYSA-N 88428 cid_9551548::SMR000128321::N-(furan-2-ylmethyl)-8-methyl-4-oxo-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide::MLS000523055::N-(furan-2-ylmethyl)-8-methyl-4-oxidanylidene-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide::N-(2-furanylmethyl)-8-methyl-4-oxo-N-(3-propan-2-yloxypropyl)-5H-thieno[3,2-c]quinoline-2-carboxamide::N-(2-furfuryl)-N-(3-isopropoxypropyl)-4-keto-8-methyl-5H-thieno[3,2-c]quinoline-2-carboxamide Melanocortin receptor 4 Homo sapiens >89225 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88428 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88428&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9551548 252660144 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192535 O=C(N\N=C\c1ccc(OCc2ccccc2)cc1)c1cccs1 InChI=1S/C19H16N2O2S/c22-19(18-7-4-12-24-18)21-20-13-15-8-10-17(11-9-15)23-14-16-5-2-1-3-6-16/h1-13H,14H2,(H,21,22) FFVGRIFNASHCKX-UHFFFAOYSA-N 88429 Thiophene-2-carboxylic acid [1-(4-benzyloxy-phenyl)-meth-(E)-ylidene]-hydrazide::N-[(E)-(4-phenylmethoxyphenyl)methylideneamino]thiophene-2-carboxamide::cid_6878737::N-[(E)-(4-phenylmethoxyphenyl)methylideneamino]-2-thiophenecarboxamide::MLS000556991::SMR000148108::N-[(E)-(4-benzoxybenzylidene)amino]thiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens >89183 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88429&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6878737 252660145 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192536 COc1ccc(NC(=O)Nc2nnc(s2)-c2ccccc2SCc2ccccc2)cc1 InChI=1S/C23H20N4O2S2/c1-29-18-13-11-17(12-14-18)24-22(28)25-23-27-26-21(31-23)19-9-5-6-10-20(19)30-15-16-7-3-2-4-8-16/h2-14H,15H2,1H3,(H2,24,25,27,28) IFQDGFMAAVFKRJ-UHFFFAOYSA-N 88430 cid_2895599::1-(4-methoxyphenyl)-3-[5-[2-(phenylmethylthio)phenyl]-1,3,4-thiadiazol-2-yl]urea::N-{5-[2-(benzylthio)phenyl]-1,3,4-thiadiazol-2-yl}-N'-(4-methoxyphenyl)urea::SMR000141645::1-[5-(2-benzylsulfanylphenyl)-1,3,4-thiadiazol-2-yl]-3-(4-methoxyphenyl)urea::1-(4-methoxyphenyl)-3-[5-[2-(phenylmethylsulfanyl)phenyl]-1,3,4-thiadiazol-2-yl]urea::MLS000534208::1-[5-[2-(benzylthio)phenyl]-1,3,4-thiadiazol-2-yl]-3-(4-methoxyphenyl)urea Melanocortin receptor 4 Homo sapiens >89220 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88430&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2895599 252660146 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192537 COc1ccc(cc1OC)-c1csc(n1)-c1c(O)cn(Cc2ccc(Cl)cc2)c1N InChI=1S/C22H20ClN3O3S/c1-28-18-8-5-14(9-19(18)29-2)16-12-30-22(25-16)20-17(27)11-26(21(20)24)10-13-3-6-15(23)7-4-13/h3-9,11-12,27H,10,24H2,1-2H3 SLLWQAHSJLQNPR-UHFFFAOYSA-N 88431 cid_2343832::5-azanyl-1-[(4-chlorophenyl)methyl]-4-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-2H-pyrrol-3-one::5-amino-1-[(4-chlorophenyl)methyl]-4-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-2H-pyrrol-3-one::SMR000152253::5-amino-1-[(4-chlorophenyl)methyl]-4-[4-(3,4-dimethoxyphenyl)-2-thiazolyl]-2H-pyrrol-3-one::MLS000564985::5-amino-1-(4-chlorobenzyl)-4-[4-(3,4-dimethoxyphenyl)thiazol-2-yl]-2-pyrrolin-3-one Melanocortin receptor 4 Homo sapiens >89175 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88431&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899114 252660147 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192538 Cc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)C(=O)C=Cc1ccccc1 |w:21.23| InChI=1S/C25H20N2O2/c1-18-11-14-20(15-12-18)24(29)17-27-22-10-6-5-9-21(22)26-25(27)23(28)16-13-19-7-3-2-4-8-19/h2-16H,17H2,1H3 URNRXQBYTUFKOE-UHFFFAOYSA-N 88432 (E)-1-[1-[2-(4-methylphenyl)-2-oxoethyl]-2-benzimidazolyl]-3-phenyl-2-propen-1-one::MLS000545812::(E)-1-[1-[2-(4-methylphenyl)-2-oxidanylidene-ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one::cid_6260079::1-{1-[2-(4-methylphenyl)-2-oxoethyl]-1H-benzimidazol-2-yl}-3-phenyl-2-propen-1-one::(E)-1-[1-[2-(4-methylphenyl)-2-oxoethyl]benzimidazol-2-yl]-3-phenylprop-2-en-1-one::SMR000163983::(E)-1-[1-[2-keto-2-(p-tolyl)ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88432&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6260079 252660148 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192539 Clc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1cc([nH]n1)-c1ccccc1 |t:8| InChI=1S/C19H13ClN6S/c20-14-8-6-13(7-9-14)17-11-27-19-24-23-18(26(19)25-17)16-10-15(21-22-16)12-4-2-1-3-5-12/h1-10H,11H2,(H,21,22) JVYMSPPKDODTNF-UHFFFAOYSA-N 79531 MLS000558549::cid_1400670::SMR000149065::6-(4-Chloro-phenyl)-3-(5-phenyl-2H-pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine::6-(4-chlorophenyl)-3-(3-phenyl-1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine Melanocortin receptor 4 Homo sapiens >89203 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79531 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79531&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1400670 252656182 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192540 C\C(=C/c1ccco1)C1C(C#N)C(=N)Oc2[nH]nc(c12)-c1ccc(C)cc1 InChI=1S/C21H18N4O2/c1-12-5-7-14(8-6-12)19-18-17(13(2)10-15-4-3-9-26-15)16(11-22)20(23)27-21(18)25-24-19/h3-10,16-17,23H,1-2H3,(H,24,25) JUYHHMJOPAMXRQ-UHFFFAOYSA-N 59898 MLS000519110::6-amino-4-[(E)-1-(furan-2-yl)prop-1-en-2-yl]-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-[(E)-1-(2-furanyl)prop-1-en-2-yl]-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::cid_11957202::SMR000129529::6-azanyl-4-[(E)-1-(furan-2-yl)prop-1-en-2-yl]-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-[(E)-2-(2-furyl)-1-methyl-vinyl]-3-(p-tolyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile Melanocortin receptor 4 Homo sapiens >89214 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59898 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59898&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91897428 252639527 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192541 COc1ccc(cc1Cl)-n1nc(C(=O)NCC(=O)Nc2ccccn2)c2ccccc2c1=O InChI=1S/C23H18ClN5O4/c1-33-18-10-9-14(12-17(18)24)29-23(32)16-7-3-2-6-15(16)21(28-29)22(31)26-13-20(30)27-19-8-4-5-11-25-19/h2-12H,13H2,1H3,(H,26,31)(H,25,27,30) DJNJAPYZRRUAEI-UHFFFAOYSA-N 41052 3-(3-chloranyl-4-methoxy-phenyl)-4-oxidanylidene-N-[2-oxidanylidene-2-(pyridin-2-ylamino)ethyl]phthalazine-1-carboxamide::3-(3-chloro-4-methoxyphenyl)-4-oxo-N-[2-oxo-2-(pyridin-2-ylamino)ethyl]phthalazine-1-carboxamide::cid_11957249::3-(3-chloro-4-methoxyphenyl)-4-oxo-N-[2-oxo-2-(2-pyridinylamino)ethyl]-1-phthalazinecarboxamide::SMR000130100::MLS000519682::3-(3-chloro-4-methoxy-phenyl)-4-keto-N-[2-keto-2-(2-pyridylamino)ethyl]phthalazine-1-carboxamide Melanocortin receptor 4 Homo sapiens >89226 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41052 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41052&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 11957249 252621829 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192542 O=C(NCc1ccco1)C(=C\c1cn(CCOc2ccccc2)c2ccccc12)\C#N InChI=1S/C25H21N3O3/c26-16-19(25(29)27-17-22-9-6-13-30-22)15-20-18-28(24-11-5-4-10-23(20)24)12-14-31-21-7-2-1-3-8-21/h1-11,13,15,18H,12,14,17H2,(H,27,29) VUZSZFJXWQQXLX-UHFFFAOYSA-N 88433 2-Cyano-N-furan-2-ylmethyl-3-[1-(2-phenoxy-ethyl)-1H-indol-3-yl]-acrylamide::(E)-2-cyano-N-(furan-2-ylmethyl)-3-[1-(2-phenoxyethyl)indol-3-yl]prop-2-enamide::MLS000557673::SMR000177357::(E)-2-cyano-N-(2-furanylmethyl)-3-[1-(2-phenoxyethyl)-3-indolyl]-2-propenamide::cid_5765807::(E)-2-cyano-N-(2-furfuryl)-3-[1-(2-phenoxyethyl)indol-3-yl]acrylamide Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88433&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5765807 252660149 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192543 CN(C)CCCNC(=O)c1ccc(cc1)-c1nc(cs1)-c1ccc(Cl)cc1 InChI=1S/C21H22ClN3OS/c1-25(2)13-3-12-23-20(26)16-4-6-17(7-5-16)21-24-19(14-27-21)15-8-10-18(22)11-9-15/h4-11,14H,3,12-13H2,1-2H3,(H,23,26) IEBUACWTCPKRKU-UHFFFAOYSA-N 65098 SMR000169436::MLS000546266::cid_3734285::4-[4-(4-chlorophenyl)-2-thiazolyl]-N-[3-(dimethylamino)propyl]benzamide::4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-N-[3-(dimethylamino)propyl]benzenecarboxamide::4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-N-[3-(dimethylamino)propyl]benzamide::4-[4-(4-chlorophenyl)thiazol-2-yl]-N-[3-(dimethylamino)propyl]benzamide Melanocortin receptor 4 Homo sapiens >9912 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65098 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65098&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3734285 252643922 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192544 COc1ccc(COc2ccsc2C(=O)Nc2ccc(Cl)c(Cl)c2)cc1 InChI=1S/C19H15Cl2NO3S/c1-24-14-5-2-12(3-6-14)11-25-17-8-9-26-18(17)19(23)22-13-4-7-15(20)16(21)10-13/h2-10H,11H2,1H3,(H,22,23) HURUJIPEGVVHKP-UHFFFAOYSA-N 88434 N-(3,4-dichlorophenyl)-3-[(4-methoxyphenyl)methoxy]thiophene-2-carboxamide::MLS000325634::N-(3,4-dichlorophenyl)-3-[(4-methoxyphenyl)methoxy]-2-thiophenecarboxamide::N-(3,4-dichlorophenyl)-3-[(4-methoxybenzyl)oxy]-2-thiophenecarboxamide::SMR000169941::cid_3365190::N-(3,4-dichlorophenyl)-3-p-anisyloxy-thiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens >89224 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88434 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88434&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3365190 252660150 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192545 Nc1c(cnn1-c1nc(cs1)-c1ccc(Cl)cc1Cl)-c1cccs1 InChI=1S/C16H10Cl2N4S2/c17-9-3-4-10(12(18)6-9)13-8-24-16(21-13)22-15(19)11(7-20-22)14-2-1-5-23-14/h1-8H,19H2 ZIGIMICLZAQPOQ-UHFFFAOYSA-N 88435 SMR000180601::MLS000327653::1-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-(2-thienyl)-1H-pyrazol-5-amine::2-[4-(2,4-dichlorophenyl)-2-thiazolyl]-4-thiophen-2-yl-3-pyrazolamine::cid_1474409::2-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-thiophen-2-yl-pyrazol-3-amine::2-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-4-thiophen-2-ylpyrazol-3-amine::[2-[4-(2,4-dichlorophenyl)thiazol-2-yl]-4-(2-thienyl)pyrazol-3-yl]amine Melanocortin receptor 4 Homo sapiens >89183 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88435&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1474409 252660151 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192546 Cc1cccc(NC(=S)NC(=O)C(c2ccccc2)c2ccccc2)n1 InChI=1S/C21H19N3OS/c1-15-9-8-14-18(22-15)23-21(26)24-20(25)19(16-10-4-2-5-11-16)17-12-6-3-7-13-17/h2-14,19H,1H3,(H2,22,23,24,25,26) UNAXUDBJJDBYRD-UHFFFAOYSA-N 88436 N-{[(6-methyl-2-pyridinyl)amino]carbonothioyl}-2,2-diphenylacetamide::SMR000195552::N-[(6-methylpyridin-2-yl)carbamothioyl]-2,2-diphenyl-ethanamide::MLS000573965::N-[(6-methylpyridin-2-yl)carbamothioyl]-2,2-diphenylacetamide::N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2,2-diphenylacetamide::cid_1224409::N-[(6-methyl-2-pyridyl)thiocarbamoyl]-2,2-diphenyl-acetamide Melanocortin receptor 4 Homo sapiens >89218 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88436 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88436&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1224409 252660152 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192547 CCOc1ccc(NC(=S)NC(=O)C=Cc2ccc(C)cc2)c(c1)[N+]([O-])=O |w:14.14| InChI=1S/C19H19N3O4S/c1-3-26-15-9-10-16(17(12-15)22(24)25)20-19(27)21-18(23)11-8-14-6-4-13(2)5-7-14/h4-12H,3H2,1-2H3,(H2,20,21,23,27) IHOWGNSDOKKWMZ-UHFFFAOYSA-N 66396 (E)-N-[(4-ethoxy-2-nitroanilino)-sulfanylidenemethyl]-3-(4-methylphenyl)-2-propenamide::(E)-N-[(4-ethoxy-2-nitro-phenyl)carbamothioyl]-3-(4-methylphenyl)prop-2-enamide::N-{[(4-ethoxy-2-nitrophenyl)amino]carbonothioyl}-3-(4-methylphenyl)acrylamide::MLS000578724::cid_5340559::SMR000186216::(E)-N-[(4-ethoxy-2-nitrophenyl)carbamothioyl]-3-(4-methylphenyl)prop-2-enamide::(E)-N-[(4-ethoxy-2-nitro-phenyl)thiocarbamoyl]-3-(p-tolyl)acrylamide Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66396 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66396&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5340559 252644719 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192548 Cc1ccc(cc1)-c1nnc(o1)-c1ccc(NC(=O)Cc2cccs2)cc1 InChI=1S/C21H17N3O2S/c1-14-4-6-15(7-5-14)20-23-24-21(26-20)16-8-10-17(11-9-16)22-19(25)13-18-3-2-12-27-18/h2-12H,13H2,1H3,(H,22,25) LRZDWJSTQDTGRF-UHFFFAOYSA-N 67944 cid_1026551::N-{4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl}-2-(2-thienyl)acetamide::SMR000201304::MLS000582086::N-[4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl]-2-thiophen-2-yl-ethanamide::N-[4-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]phenyl]-2-thiophen-2-ylacetamide::N-[4-[5-(p-tolyl)-1,3,4-oxadiazol-2-yl]phenyl]-2-(2-thienyl)acetamide Melanocortin receptor 4 Homo sapiens >89213 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67944 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67944&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1026551 252646224 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192549 Clc1ccc(cc1NC(=O)c1ccc2OCOc2c1)-c1nc2ccccc2s1 InChI=1S/C21H13ClN2O3S/c22-14-7-5-13(21-24-15-3-1-2-4-19(15)28-21)9-16(14)23-20(25)12-6-8-17-18(10-12)27-11-26-17/h1-10H,11H2,(H,23,25) QGYZAWCNJCDUSE-UHFFFAOYSA-N 88437 Benzo[1,3]dioxole-5-carboxylic acid (5-benzothiazol-2-yl-2-chloro-phenyl)-amide::N-[5-(1,3-benzothiazol-2-yl)-2-chloranyl-phenyl]-1,3-benzodioxole-5-carboxamide::MLS000560266::cid_1090028::SMR000178540::N-[5-(1,3-benzothiazol-2-yl)-2-chlorophenyl]-1,3-benzodioxole-5-carboxamide::N-[5-(1,3-benzothiazol-2-yl)-2-chloro-phenyl]-piperonylamide Melanocortin receptor 4 Homo sapiens >89177 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88437 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88437&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1090028 252660153 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192550 Clc1ccc(cc1)-c1nn(cc1C=c1c(=C)[nH][nH]c1=O)-c1ccccc1 |w:12.13| InChI=1S/C20H15ClN4O/c1-13-18(20(26)23-22-13)11-15-12-25(17-5-3-2-4-6-17)24-19(15)14-7-9-16(21)10-8-14/h2-12,22H,1H2,(H,23,26) IMWNNTDQVMEOES-UHFFFAOYSA-N 57456 SMR000193592::(4Z)-4-[[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]methylidene]-3-methyl-1H-pyrazol-5-one::(4Z)-4-[[3-(4-chlorophenyl)-1-phenyl-4-pyrazolyl]methylidene]-3-methyl-1H-pyrazol-5-one::MLS000571227::(4Z)-4-[[3-(4-chlorophenyl)-1-phenyl-pyrazol-4-yl]methylidene]-3-methyl-1H-pyrazol-5-one::4-{[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-5-methyl-2,4-dihydro-3H-pyrazol-3-one::cid_5508807::(4Z)-4-[[3-(4-chlorophenyl)-1-phenyl-pyrazol-4-yl]methylene]-5-methyl-2-pyrazolin-3-one Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57456&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2218177 252637386 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192551 Cc1cc(C)cc(OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 InChI=1S/C29H32N2O4/c1-19-13-20(2)15-24(14-19)35-18-23(32)17-30-11-9-21(10-12-30)16-31-28(33)25-7-3-5-22-6-4-8-26(27(22)25)29(31)34/h3-8,13-15,21,23,32H,9-12,16-18H2,1-2H3 FRBVGIBVLCZGTH-UHFFFAOYSA-N 79535 2-[[1-[3-(3,5-dimethylphenoxy)-2-oxidanyl-propyl]piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::MLS000572689::SMR000194551::cid_2892066::2-[[1-[3-(3,5-dimethylphenoxy)-2-hydroxypropyl]-4-piperidinyl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-({1-[3-(3,5-dimethylphenoxy)-2-hydroxypropyl]-4-piperidinyl}methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione hydrochloride::2-[[1-[3-(3,5-dimethylphenoxy)-2-hydroxypropyl]piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-[[1-[3-(3,5-dimethylphenoxy)-2-hydroxy-propyl]-4-piperidyl]methyl]benzo[de]isoquinoline-1,3-quinone;hydrochloride Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79535 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79535&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2892067 252656186 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192552 OC(COc1ccc2ccccc2c1)CN1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1 InChI=1S/C31H30N2O4/c34-25(20-37-26-12-11-22-5-1-2-6-24(22)17-26)19-32-15-13-21(14-16-32)18-33-30(35)27-9-3-7-23-8-4-10-28(29(23)27)31(33)36/h1-12,17,21,25,34H,13-16,18-20H2 TXPRPLRWADQUKQ-UHFFFAOYSA-N 57475 MLS000572681::cid_2891886::2-[[1-(3-naphthalen-2-yloxy-2-oxidanyl-propyl)piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::SMR000194544::2-[[1-(2-hydroxy-3-naphthalen-2-yloxypropyl)piperidin-4-yl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-[[1-[2-hydroxy-3-(2-naphthalenyloxy)propyl]-4-piperidinyl]methyl]benzo[de]isoquinoline-1,3-dione;hydrochloride::2-({1-[2-hydroxy-3-(2-naphthyloxy)propyl]-4-piperidinyl}methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione hydrochloride::2-[[1-[2-hydroxy-3-(2-naphthoxy)propyl]-4-piperidyl]methyl]benzo[de]isoquinoline-1,3-quinone;hydrochloride Melanocortin receptor 4 Homo sapiens 6308 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57475 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57475&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2891887 252637405 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192553 CCOC(=O)c1ccc(cc1)-c1ccc(\C=C(/C#N)C(=O)NCc2cccs2)o1 InChI=1S/C22H18N2O4S/c1-2-27-22(26)16-7-5-15(6-8-16)20-10-9-18(28-20)12-17(13-23)21(25)24-14-19-4-3-11-29-19/h3-12H,2,14H2,1H3,(H,24,25) GBGGAVSVZFLWEL-UHFFFAOYSA-N 88438 4-(5-{2-Cyano-2-[(thiophen-2-ylmethyl)-carbamoyl]-vinyl}-furan-2-yl)-benzoic acid ethyl ester::SMR000177362::4-[5-[(E)-2-cyano-3-oxo-3-(thiophen-2-ylmethylamino)prop-1-enyl]-2-furanyl]benzoic acid ethyl ester::ethyl 4-[5-[(E)-2-cyano-3-oxidanylidene-3-(thiophen-2-ylmethylamino)prop-1-enyl]furan-2-yl]benzoate::MLS000551866::cid_1073607::ethyl 4-[5-[(E)-2-cyano-3-oxo-3-(thiophen-2-ylmethylamino)prop-1-enyl]furan-2-yl]benzoate::4-[5-[(E)-2-cyano-3-keto-3-(2-thenylamino)prop-1-enyl]-2-furyl]benzoic acid ethyl ester Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88438 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88438&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1073607 252660154 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192554 Cc1ccc(NC(=S)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)c(O)c1 InChI=1S/C19H15ClN2O3S/c1-11-2-7-14(15(23)10-11)21-19(26)22-18(24)17-9-8-16(25-17)12-3-5-13(20)6-4-12/h2-10,23H,1H3,(H2,21,22,24,26) KWZVCVLXTVLJFJ-UHFFFAOYSA-N 88439 5-(4-chlorophenyl)-N-{[(2-hydroxy-4-methylphenyl)amino]carbonothioyl}-2-furamide::cid_1048268::MLS000574087::SMR000195672::5-(4-chlorophenyl)-N-[(2-hydroxy-4-methylphenyl)carbamothioyl]furan-2-carboxamide::5-(4-chlorophenyl)-N-[(4-methyl-2-oxidanyl-phenyl)carbamothioyl]furan-2-carboxamide::5-(4-chlorophenyl)-N-[(2-hydroxy-4-methylanilino)-sulfanylidenemethyl]-2-furancarboxamide::5-(4-chlorophenyl)-N-[(2-hydroxy-4-methyl-phenyl)thiocarbamoyl]-2-furamide Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88439 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88439&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1048268 252660155 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192555 CC(C=CC=Cc1ccccc1)=NNC(=O)CNc1ccccc1C |w:12.13,5.5,2.1| InChI=1S/C21H23N3O/c1-17-10-6-9-15-20(17)22-16-21(25)24-23-18(2)11-7-8-14-19-12-4-3-5-13-19/h3-15,22H,16H2,1-2H3,(H,24,25) NZZQVKAKUYOZOA-UHFFFAOYSA-N 88440 cid_6241538::MLS000578706::2-[(2-methylphenyl)amino]-N-[(Z)-[(3E,5E)-6-phenylhexa-3,5-dien-2-ylidene]amino]ethanamide::SMR000186258::2-[(2-methylphenyl)amino]-N'-(1-methyl-5-phenyl-2,4-pentadien-1-ylidene)acetohydrazide (non-preferred name)::2-(2-methylanilino)-N-[(Z)-[(3E,5E)-6-phenylhexa-3,5-dien-2-ylidene]amino]acetamide::N-[(Z)-[(2E,4E)-1-methyl-5-phenyl-penta-2,4-dienylidene]amino]-2-(o-toluidino)acetamide Melanocortin receptor 4 Homo sapiens >89269 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88440 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88440&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6241538 252660156 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192556 CCc1ccc(CCC(=O)Nc2ncc(Cc3ccccc3Cl)s2)o1 InChI=1S/C19H19ClN2O2S/c1-2-14-7-8-15(24-14)9-10-18(23)22-19-21-12-16(25-19)11-13-5-3-4-6-17(13)20/h3-8,12H,2,9-11H2,1H3,(H,21,22,23) KUVALWKDLVTCGG-UHFFFAOYSA-N 88441 SMR000200154::N-[5-[(2-chlorophenyl)methyl]-2-thiazolyl]-3-(5-ethyl-2-furanyl)propanamide::cid_1873833::N-[5-(2-chlorobenzyl)-1,3-thiazol-2-yl]-3-(5-ethyl-2-furyl)propanamide::MLS000581527::N-[5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl]-3-(5-ethylfuran-2-yl)propanamide::N-[5-(2-chlorobenzyl)thiazol-2-yl]-3-(5-ethyl-2-furyl)propionamide Melanocortin receptor 4 Homo sapiens >89207 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88441 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88441&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1873833 252660157 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192557 O=C(NN=Cc1c[nH]c2ccccc12)C1CC1(c1ccccc1)c1ccccc1 |w:3.2| InChI=1S/C25H21N3O/c29-24(28-27-17-18-16-26-23-14-8-7-13-21(18)23)22-15-25(22,19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-14,16-17,22,26H,15H2,(H,28,29) HHLPSPFZUGDXCY-UHFFFAOYSA-N 79537 SMR000184430::N'-(1H-indol-3-ylmethylene)-2,2-diphenylcyclopropanecarbohydrazide::N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropane-1-carbohydrazide::MLS000595044::N'-[(Z)-3-indolylidenemethyl]-2,2-diphenyl-1-cyclopropanecarbohydrazide::N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenylcyclopropane-1-carbohydrazide::cid_5717454::N'-[(Z)-indol-3-ylidenemethyl]-2,2-diphenyl-cyclopropanecarbohydrazide Melanocortin receptor 4 Homo sapiens >89201 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79537 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79537&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5717454 252656188 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192558 Cc1nc(NC(=O)c2cccc(c2)-c2cc3ccccc3oc2=O)ccc1Br InChI=1S/C22H15BrN2O3/c1-13-18(23)9-10-20(24-13)25-21(26)16-7-4-6-14(11-16)17-12-15-5-2-3-8-19(15)28-22(17)27/h2-12H,1H3,(H,24,25,26) LZDQKGBRYFXSLM-UHFFFAOYSA-N 55532 N-(5-bromanyl-6-methyl-pyridin-2-yl)-3-(2-oxidanylidenechromen-3-yl)benzamide::N-(5-bromo-6-methylpyridin-2-yl)-3-(2-oxochromen-3-yl)benzamide::MLS000582933::N-(5-bromo-6-methyl-2-pyridinyl)-3-(2-oxo-1-benzopyran-3-yl)benzamide::SMR000201639::N-(5-bromo-6-methyl-2-pyridinyl)-3-(2-oxo-2H-chromen-3-yl)benzamide::cid_1258911::N-(5-bromo-6-methyl-2-pyridyl)-3-(2-ketochromen-3-yl)benzamide Melanocortin receptor 4 Homo sapiens >89186 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55532 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55532&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1258911 252635528 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192559 O=C(NC(=S)Nc1cccc(NC(=O)c2ccccc2)c1)c1cccs1 InChI=1S/C19H15N3O2S2/c23-17(13-6-2-1-3-7-13)20-14-8-4-9-15(12-14)21-19(25)22-18(24)16-10-5-11-26-16/h1-12H,(H,20,23)(H2,21,22,24,25) FOHIIVAKMDSIAO-UHFFFAOYSA-N 88442 SMR000194752::cid_1349192::N-[(3-benzamidoanilino)-sulfanylidenemethyl]-2-thiophenecarboxamide::N-[(3-benzamidophenyl)carbamothioyl]thiophene-2-carboxamide::MLS000573251::N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-2-thiophenecarboxamide::N-[(3-benzamidophenyl)thiocarbamoyl]thiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens >89200 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88442&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1349192 252660158 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192560 CCC(C)c1ccc(NC(=S)NC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C23H31N3S/c1-3-18(2)20-9-11-21(12-10-20)24-23(27)25-22-13-15-26(16-14-22)17-19-7-5-4-6-8-19/h4-12,18,22H,3,13-17H2,1-2H3,(H2,24,25,27) IHLQVRGYCNKFET-UHFFFAOYSA-N 88443 1-(1-benzylpiperidin-4-yl)-3-(4-butan-2-ylphenyl)thiourea::N-(1-benzyl-4-piperidinyl)-N'-(4-sec-butylphenyl)thiourea::MLS000581437::1-(4-butan-2-ylphenyl)-3-[1-(phenylmethyl)-4-piperidinyl]thiourea::SMR000200062::1-(4-butan-2-ylphenyl)-3-[1-(phenylmethyl)piperidin-4-yl]thiourea::cid_2957625::1-(1-benzyl-4-piperidyl)-3-(4-sec-butylphenyl)thiourea Melanocortin receptor 4 Homo sapiens >9913 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88443 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88443&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2957625 252660159 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192561 O=C(CSc1ccccc1)Nc1nnc(\C=C\c2ccccc2)s1 InChI=1S/C18H15N3OS2/c22-16(13-23-15-9-5-2-6-10-15)19-18-21-20-17(24-18)12-11-14-7-3-1-4-8-14/h1-12H,13H2,(H,19,21,22) MLKIZLJGLAQXQI-UHFFFAOYSA-N 88444 cid_5739567::N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-phenylsulfanylacetamide::2-(phenylthio)-N-[5-(2-phenylvinyl)-1,3,4-thiadiazol-2-yl]acetamide::N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-phenylsulfanyl-ethanamide::SMR000199630::MLS000580100::N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-(phenylthio)acetamide::2-(phenylthio)-N-[5-[(E)-styryl]-1,3,4-thiadiazol-2-yl]acetamide Melanocortin receptor 4 Homo sapiens >89222 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88444 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88444&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5739567 252660160 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192562 Cc1ccc(OCC(=O)NC(=S)Nc2cccc(NC(=O)c3ccccc3)c2)cc1 InChI=1S/C23H21N3O3S/c1-16-10-12-20(13-11-16)29-15-21(27)26-23(30)25-19-9-5-8-18(14-19)24-22(28)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H,24,28)(H2,25,26,27,30) SCHJAWUACXHPSB-UHFFFAOYSA-N 87827 SMR000194754::cid_1349228::N-{3-[({[(4-methylphenoxy)acetyl]amino}carbonothioyl)amino]phenyl}benzamide::MLS000573253::N-[3-[2-(4-methylphenoxy)ethanoylcarbamothioylamino]phenyl]benzamide::N-[3-[[[[2-(4-methylphenoxy)-1-oxoethyl]amino]-sulfanylidenemethyl]amino]phenyl]benzamide::N-[3-[[2-(4-methylphenoxy)acetyl]carbamothioylamino]phenyl]benzamide::N-[3-[[2-(4-methylphenoxy)acetyl]thiocarbamoylamino]phenyl]benzamide Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87827 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87827&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1349228 252660090 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192563 Oc1cc2ccccc2cc1C(=O)N\N=C1/C(=O)N(Cc2ccccc2)c2ccccc12 InChI=1S/C26H19N3O3/c30-23-15-19-11-5-4-10-18(19)14-21(23)25(31)28-27-24-20-12-6-7-13-22(20)29(26(24)32)16-17-8-2-1-3-9-17/h1-15,30H,16H2,(H,28,31) DJDGFPSMHPOXPK-UHFFFAOYSA-N 50213 MLS000553595::3-oxidanyl-N-[(Z)-[2-oxidanylidene-1-(phenylmethyl)indol-3-ylidene]amino]naphthalene-2-carboxamide::3-hydroxy-N-[(Z)-[2-oxo-1-(phenylmethyl)-3-indolylidene]amino]-2-naphthalenecarboxamide::cid_9591396::N-[(Z)-(1-benzyl-2-oxoindol-3-ylidene)amino]-3-hydroxynaphthalene-2-carboxamide::SMR000171355::3-Hydroxy-naphthalene-2-carboxylic acid (1-benzyl-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazide::N-[(Z)-(1-benzyl-2-keto-indolin-3-ylidene)amino]-3-hydroxy-2-naphthamide Melanocortin receptor 4 Homo sapiens >89183 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9591396 252630479 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192564 COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3sc4ccccc4c3Cl)cc2)ncn1 InChI=1S/C21H16ClN5O4S3/c1-31-17-10-16(23-11-24-17)27-34(29,30)13-8-6-12(7-9-13)25-21(32)26-20(28)19-18(22)14-4-2-3-5-15(14)33-19/h2-11H,1H3,(H,23,24,27)(H2,25,26,28,32) VORJZSTVGWKIKN-UHFFFAOYSA-N 88445 cid_1865512::3-chloro-N-[[4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl]carbamothioyl]-1-benzothiophene-2-carboxamide::4-[3-(3-Chloro-benzo[b]thiophene-2-carbonyl)-thioureido]-N-(6-methoxy-pyrimidin-4-yl)-benzenesulfonamide::SMR000171332::MLS000553910::3-chloro-N-[[4-[(6-methoxy-4-pyrimidinyl)sulfamoyl]anilino]-sulfanylidenemethyl]-1-benzothiophene-2-carboxamide::3-chloranyl-N-[[4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl]carbamothioyl]-1-benzothiophene-2-carboxamide::3-chloro-N-[[4-[(6-methoxypyrimidin-4-yl)sulfamoyl]phenyl]thiocarbamoyl]benzothiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens >89165 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88445&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1865512 252660161 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192565 COc1ccc2oc(=O)c(cc2c1)-c1csc(Nc2cccc(O)c2)n1 InChI=1S/C19H14N2O4S/c1-24-14-5-6-17-11(7-14)8-15(18(23)25-17)16-10-26-19(21-16)20-12-3-2-4-13(22)9-12/h2-10,22H,1H3,(H,20,21) DGMUCJVEVOZWBL-UHFFFAOYSA-N 78178 cid_1077600::3-[2-(3-hydroxyanilino)-1,3-thiazol-4-yl]-6-methoxychromen-2-one::3-[2-(3-hydroxyanilino)-4-thiazolyl]-6-methoxy-1-benzopyran-2-one::3-[2-(3-Hydroxy-phenylamino)-thiazol-4-yl]-6-methoxy-chromen-2-one::MLS000548677::3-[2-[(3-hydroxyphenyl)amino]-1,3-thiazol-4-yl]-6-methoxy-chromen-2-one::SMR000172285::3-[2-(3-hydroxyanilino)thiazol-4-yl]-6-methoxy-coumarin Melanocortin receptor 4 Homo sapiens >89175 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78178&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1077600 252654940 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192566 CCOc1ccc(Cn2c3ccc(OC)cc3c3nc4ccccc4nc23)cc1 InChI=1S/C24H21N3O2/c1-3-29-17-10-8-16(9-11-17)15-27-22-13-12-18(28-2)14-19(22)23-24(27)26-21-7-5-4-6-20(21)25-23/h4-14H,3,15H2,1-2H3 UXEZGWBHGISAAU-UHFFFAOYSA-N 50991 SMR000220899::6-(4-Ethoxy-benzyl)-9-methoxy-6H-indolo[2,3-b]quinoxaline::cid_4318329::6-[(4-ethoxyphenyl)methyl]-9-methoxy-indolo[3,2-b]quinoxaline::MLS000331363::6-[(4-ethoxyphenyl)methyl]-9-methoxyindolo[3,2-b]quinoxaline::6-(4-ethoxybenzyl)-9-methoxy-indolo[3,2-b]quinoxaline Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50991 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50991&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4318329 252631231 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192567 Cc1cccc(OCCn2cccc2CN=Nc2nc3ccccc3s2)c1 |w:15.15| InChI=1S/C21H20N4OS/c1-16-6-4-8-18(14-16)26-13-12-25-11-5-7-17(25)15-22-24-21-23-19-9-2-3-10-20(19)27-21/h2-11,14H,12-13,15H2,1H3 GOIHVAUEXXQYIP-UHFFFAOYSA-N 88446 cid_6891712::MLS000589686::SMR000219486::N-Benzothiazol-2-yl-N'-[1-[1-(2-m-tolyloxy-ethyl)-1H-pyrrol-2-yl]-meth-(E)-ylidene]-hydrazine::N-[(E)-[1-[2-(3-methylphenoxy)ethyl]-2-pyrrolyl]methylideneamino]-1,3-benzothiazol-2-amine::N-[(E)-[1-[2-(3-methylphenoxy)ethyl]pyrrol-2-yl]methylideneamino]-1,3-benzothiazol-2-amine::1,3-benzothiazol-2-yl-[(E)-[1-[2-(3-methylphenoxy)ethyl]pyrrol-2-yl]methyleneamino]amine Melanocortin receptor 4 Homo sapiens >89196 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88446 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88446&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899115 252660162 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192568 Fc1ccccc1OCCn1cc(\C=C(/C#N)C(=O)NCc2cccs2)c2ccccc12 InChI=1S/C25H20FN3O2S/c26-22-8-2-4-10-24(22)31-12-11-29-17-19(21-7-1-3-9-23(21)29)14-18(15-27)25(30)28-16-20-6-5-13-32-20/h1-10,13-14,17H,11-12,16H2,(H,28,30) LBUYEQZOOVDBSJ-UHFFFAOYSA-N 88447 (E)-2-cyano-3-[1-[2-(2-fluorophenoxy)ethyl]-3-indolyl]-N-(thiophen-2-ylmethyl)-2-propenamide::2-Cyano-3-{1-[2-(2-fluoro-phenoxy)-ethyl]-1H-indol-3-yl}-N-thiophen-2-ylmethyl-acrylamide::cid_1132167::MLS000563936::SMR000177627::(E)-2-cyano-3-[1-[2-(2-fluorophenoxy)ethyl]indol-3-yl]-N-(thiophen-2-ylmethyl)prop-2-enamide::(E)-2-cyano-3-[1-[2-(2-fluoranylphenoxy)ethyl]indol-3-yl]-N-(thiophen-2-ylmethyl)prop-2-enamide::(E)-2-cyano-3-[1-[2-(2-fluorophenoxy)ethyl]indol-3-yl]-N-(2-thenyl)acrylamide Melanocortin receptor 4 Homo sapiens >89170 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88447 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88447&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1132167 252660163 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192569 CCOC(=O)Cc1csc(NC(=O)c2sc3nc4cc(C)ccc4cc3c2N)n1 InChI=1S/C20H18N4O3S2/c1-3-27-15(25)8-12-9-28-20(22-12)24-18(26)17-16(21)13-7-11-5-4-10(2)6-14(11)23-19(13)29-17/h4-7,9H,3,8,21H2,1-2H3,(H,22,24,26) DGVJQCOKXOACNG-UHFFFAOYSA-N 52442 cid_3167478::SMR000172488::MLS000564527::{2-[(3-Amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)-amino]-thiazol-4-yl}-acetic acid ethyl ester::ethyl 2-[2-[(3-azanyl-7-methyl-thieno[2,3-b]quinolin-2-yl)carbonylamino]-1,3-thiazol-4-yl]ethanoate::ethyl 2-[2-[(3-amino-7-methylthieno[2,3-b]quinoline-2-carbonyl)amino]-1,3-thiazol-4-yl]acetate::2-[2-[[(3-amino-7-methyl-2-thieno[2,3-b]quinolinyl)-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl ester::2-[2-[(3-amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)amino]thiazol-4-yl]acetic acid ethyl ester Melanocortin receptor 4 Homo sapiens >89176 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52442&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3167478 252632585 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192570 CCOc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)-c2cccs2)c(c1)[N+]([O-])=O InChI=1S/C19H15F3N4O4S2/c1-2-30-11-5-6-12(14(8-11)26(28)29)23-17(27)10-32-18-24-13(15-4-3-7-31-15)9-16(25-18)19(20,21)22/h3-9H,2,10H2,1H3,(H,23,27) SZWONFPBJJTSOV-UHFFFAOYSA-N 88448 cid_3145758::MLS000559812::N-(4-Ethoxy-2-nitro-phenyl)-2-(4-thiophen-2-yl-6-trifluoromethyl-pyrimidin-2-ylsulfanyl)-acetamide::N-(4-ethoxy-2-nitrophenyl)-2-[4-thiophen-2-yl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanylacetamide::N-(4-ethoxy-2-nitrophenyl)-2-[[4-thiophen-2-yl-6-(trifluoromethyl)-2-pyrimidinyl]thio]acetamide::N-(4-ethoxy-2-nitro-phenyl)-2-[4-thiophen-2-yl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl-ethanamide::SMR000177880::N-(4-ethoxy-2-nitro-phenyl)-2-[[4-(2-thienyl)-6-(trifluoromethyl)pyrimidin-2-yl]thio]acetamide Melanocortin receptor 4 Homo sapiens >89216 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88448 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88448&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3145758 252660164 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192571 CC(C)c1ccc(NC(=O)CSc2ncccc2C(=O)Oc2cccc(c2)[N+]([O-])=O)cc1 InChI=1S/C23H21N3O5S/c1-15(2)16-8-10-17(11-9-16)25-21(27)14-32-22-20(7-4-12-24-22)23(28)31-19-6-3-5-18(13-19)26(29)30/h3-13,15H,14H2,1-2H3,(H,25,27) VPYFBCIKZIHNPB-UHFFFAOYSA-N 59960 (3-nitrophenyl) 2-[2-oxo-2-(4-propan-2-ylanilino)ethyl]sulfanylpyridine-3-carboxylate::SMR000207006::(3-nitrophenyl) 2-[2-oxidanylidene-2-[(4-propan-2-ylphenyl)amino]ethyl]sulfanylpyridine-3-carboxylate::3-nitrophenyl 2-({2-[(4-isopropylphenyl)amino]-2-oxoethyl}thio)nicotinate::MLS000584020::cid_4066820::2-[[2-oxo-2-(4-propan-2-ylanilino)ethyl]thio]-3-pyridinecarboxylic acid (3-nitrophenyl) ester::2-[(2-cumidino-2-keto-ethyl)thio]nicotinic acid (3-nitrophenyl) ester Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59960 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59960&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4066820 252639586 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192572 Nc1ccc(cc1)C1(c2ccccc2-c2ccccc12)c1ccc(N)cc1 InChI=1S/C25H20N2/c26-19-13-9-17(10-14-19)25(18-11-15-20(27)16-12-18)23-7-3-1-5-21(23)22-6-2-4-8-24(22)25/h1-16H,26-27H2 KIFDSGGWDIVQGN-UHFFFAOYSA-N 88449 SMR000203330::cid_631552::4-[9-(4-aminophenyl)-9H-fluoren-9-yl]phenylamine::MLS000584167::4-[9-(4-aminophenyl)fluoren-9-yl]aniline::4-[9-(4-aminophenyl)-9-fluorenyl]aniline::[4-[9-(4-aminophenyl)fluoren-9-yl]phenyl]amine Melanocortin receptor 4 Homo sapiens >89180 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88449 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88449&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 631552 252660165 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192573 CCCOC(=O)c1cccc(Nc2nc(nc3ccccc23)-c2cccnc2)c1 InChI=1S/C23H20N4O2/c1-2-13-29-23(28)16-7-5-9-18(14-16)25-22-19-10-3-4-11-20(19)26-21(27-22)17-8-6-12-24-15-17/h3-12,14-15H,2,13H2,1H3,(H,25,26,27) GROCSHUQOZDEOU-UHFFFAOYSA-N 78656 cid_1563678::3-[[2-(3-pyridinyl)-4-quinazolinyl]amino]benzoic acid propyl ester::MLS000585144::SMR000203907::propyl 3-[(2-pyridin-3-ylquinazolin-4-yl)amino]benzoate::3-[[2-(3-pyridyl)quinazolin-4-yl]amino]benzoic acid propyl ester Melanocortin receptor 4 Homo sapiens >89278 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78656 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78656&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1563678 252655399 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192574 [#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-1-[#6]=[#6]\[#6](=[#6]\[#7+]=O)-[#6]=[#6]-1 |c:17,23| InChI=1S/C22N2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-24-19-16-22(17-20-24)21-23-25/q+1 RXAMACVYXHTIAQ-UHFFFAOYSA-N 48732 SMR000212939::cid_11293258::(1-hexadecylpyridin-4-ylidene)methyl-oxoazanium;bromide::(1-hexadecyl-4-pyridinylidene)methyl-oxoammonium;bromide::1-Hexadecyl-4-(hydroxyimino-methyl)-pyridinium::MLS000589587::(1-hexadecylpyridin-4-ylidene)methyl-oxidanylidene-azanium;bromide::(1-cetyl-4-pyridylidene)methyl-keto-ammonium;bromide Melanocortin receptor 4 Homo sapiens >3304 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48732 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48732&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5917803 252629019 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192575 CCCOc1ccc(cc1)C(=O)C(CCC(CNCC)C(=O)c1ccc(OCCC)cc1)CNCC InChI=1S/C30H44N2O4/c1-5-19-35-27-15-11-23(12-16-27)29(33)25(21-31-7-3)9-10-26(22-32-8-4)30(34)24-13-17-28(18-14-24)36-20-6-2/h11-18,25-26,31-32H,5-10,19-22H2,1-4H3 CKJMLCBLCIPXFD-UHFFFAOYSA-N 41950 MLS000587374::SMR000211418::cid_12005598::2,5-Bis-ethylaminomethyl-1,6-bis-(4-propoxy-phenyl)-hexane-1,6-dione::2,5-bis(ethylaminomethyl)-1,6-bis(4-propoxyphenyl)hexane-1,6-dione;hydrochloride Melanocortin receptor 4 Homo sapiens >89245 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41950 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41950&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3835696 252622666 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192576 CCOc1ccc(Cn2c3ccc(OC)cc3c3nc4ccccc4nc23)cc1OC InChI=1S/C25H23N3O3/c1-4-31-22-12-9-16(13-23(22)30-3)15-28-21-11-10-17(29-2)14-18(21)24-25(28)27-20-8-6-5-7-19(20)26-24/h5-14H,4,15H2,1-3H3 RFEIWHMQKOIPCS-UHFFFAOYSA-N 51029 MLS000331086::6-[(4-ethoxy-3-methoxy-phenyl)methyl]-9-methoxy-indolo[3,2-b]quinoxaline::6-(4-Ethoxy-3-methoxy-benzyl)-9-methoxy-6H-indolo[2,3-b]quinoxaline::cid_1858122::6-[(4-ethoxy-3-methoxyphenyl)methyl]-9-methoxyindolo[3,2-b]quinoxaline::SMR000221179::6-(4-ethoxy-3-methoxy-benzyl)-9-methoxy-indolo[3,2-b]quinoxaline Melanocortin receptor 4 Homo sapiens >89179 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51029 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51029&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1858122 252631269 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192577 Nc1c(sc2nc(cc(-c3ccc(F)cc3)c12)-c1cccs1)C#N InChI=1S/C18H10FN3S2/c19-11-5-3-10(4-6-11)12-8-13(14-2-1-7-23-14)22-18-16(12)17(21)15(9-20)24-18/h1-8H,21H2 VNWFBDNPAQMDRO-UHFFFAOYSA-N 88450 3-amino-4-(4-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carbonitrile::3-amino-4-(4-fluorophenyl)-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarbonitrile::3-Amino-4-(4-fluoro-phenyl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carbonitrile::SMR000219939::MLS000588536::cid_4271672::3-azanyl-4-(4-fluorophenyl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carbonitrile::3-amino-4-(4-fluorophenyl)-6-(2-thienyl)thieno[2,3-b]pyridine-2-carbonitrile Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88450 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88450&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4271672 252660166 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192578 Cc1ccc(O)c(c1)C(=O)\C=C\c1ccc2OCCCOc2c1 InChI=1S/C19H18O4/c1-13-3-6-16(20)15(11-13)17(21)7-4-14-5-8-18-19(12-14)23-10-2-9-22-18/h3-8,11-12,20H,2,9-10H2,1H3 SVROXXYUUPPUDJ-UHFFFAOYSA-N 88451 MLS000590488::SMR000217530::cid_5708658::(E)-3-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-1-(2-hydroxy-5-methyl-phenyl)-propenone::(E)-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-1-(5-methyl-2-oxidanyl-phenyl)prop-2-en-1-one::(E)-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one::(E)-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-1-(2-hydroxy-5-methylphenyl)-2-propen-1-one::(E)-3-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-1-(2-hydroxy-5-methyl-phenyl)prop-2-en-1-one Melanocortin receptor 4 Homo sapiens >89224 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88451&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5708658 252660167 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192579 CC12CCC3C(CC=C4CC(O)CCC34C)C1C\C(=C/c1ccccc1F)C2=O |t:7| InChI=1S/C26H31FO2/c1-25-11-9-19(28)15-18(25)7-8-20-21(25)10-12-26(2)22(20)14-17(24(26)29)13-16-5-3-4-6-23(16)27/h3-7,13,19-22,28H,8-12,14-15H2,1-2H3 GEMAOHATSXXMSE-UHFFFAOYSA-N 88452 (16E)-16-[(2-fluorophenyl)methylidene]-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one::MLS000418875::SMR000236871::cid_12006041::(16E)-16-[(2-fluorophenyl)methylidene]-10,13-dimethyl-3-oxidanyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one::(16E)-16-(2-fluorobenzylidene)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-one Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88452 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88452&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 12006041 252660168 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192580 CN(C)CCCN(C(=O)CCc1ccccc1)c1nc2ccc(Cl)cc2s1 InChI=1S/C21H24ClN3OS/c1-24(2)13-6-14-25(20(26)12-9-16-7-4-3-5-8-16)21-23-18-11-10-17(22)15-19(18)27-21/h3-5,7-8,10-11,15H,6,9,12-14H2,1-2H3 KCFPBOJFZSCOAD-UHFFFAOYSA-N 88453 MLS000696694::cid_12006131::N-(6-chloro-1,3-benzothiazol-2-yl)-N-[3-(dimethylamino)propyl]-3-phenylpropanamide;hydrochloride::N-(6-chloranyl-1,3-benzothiazol-2-yl)-N-[3-(dimethylamino)propyl]-3-phenyl-propanamide;hydrochloride::SMR000237217::N-(6-chloro-1,3-benzothiazol-2-yl)-N-[3-(dimethylamino)propyl]-3-phenyl-propionamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89174 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88453&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 7208717 252660169 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192581 Fc1ccc(cc1)-c1ccc(\C=C(/C#N)C(=O)Nc2nc(cs2)-c2cccs2)o1 InChI=1S/C21H12FN3O2S2/c22-15-5-3-13(4-6-15)18-8-7-16(27-18)10-14(11-23)20(26)25-21-24-17(12-29-21)19-2-1-9-28-19/h1-10,12H,(H,24,25,26) ULZPTBQRPJKARJ-UHFFFAOYSA-N 74865 (E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-thiophen-2-yl-2-thiazolyl)-2-propenamide::SMR000262229::cid_2328888::(E)-2-cyano-3-[5-(4-fluorophenyl)furan-2-yl]-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)prop-2-enamide::MLS000402434::(E)-2-cyano-3-[5-(4-fluorophenyl)-2-furyl]-N-[4-(2-thienyl)thiazol-2-yl]acrylamide Melanocortin receptor 4 Homo sapiens >89170 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=74865 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=74865&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2328888 252652083 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192582 OC(CNCCc1ccc(cc1)C(F)(F)F)COc1cccc2ccccc12 InChI=1S/C22H22F3NO2/c23-22(24,25)18-10-8-16(9-11-18)12-13-26-14-19(27)15-28-21-7-3-5-17-4-1-2-6-20(17)21/h1-11,19,26-27H,12-15H2 YZGTUSIIFSUYJX-UHFFFAOYSA-N 68044 cid_3605184::SMR000249129::1-naphthalen-1-yloxy-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol::MLS000334371::1-(1-naphthalenyloxy)-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]-2-propanol::1-(1-naphthoxy)-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol Melanocortin receptor 4 Homo sapiens >89205 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68044 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68044&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3605184 252646323 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192583 Cc1ccccc1NC(=O)c1ccc(COc2ccc3c(C)cc(=O)oc3c2)cc1 InChI=1S/C25H21NO4/c1-16-5-3-4-6-22(16)26-25(28)19-9-7-18(8-10-19)15-29-20-11-12-21-17(2)13-24(27)30-23(21)14-20/h3-14H,15H2,1-2H3,(H,26,28) KPZNLGMSMWFCFG-UHFFFAOYSA-N 88454 4-[(4-methyl-2-oxidanylidene-chromen-7-yl)oxymethyl]-N-(2-methylphenyl)benzamide::cid_2102682::4-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxymethyl]-N-(2-methylphenyl)benzamide::SMR000249861::MLS000335103::4-[(4-methyl-2-oxochromen-7-yl)oxymethyl]-N-(2-methylphenyl)benzamide::4-[(2-keto-4-methyl-chromen-7-yl)oxymethyl]-N-(o-tolyl)benzamide Melanocortin receptor 4 Homo sapiens >89263 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88454&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2102682 252660170 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192584 COC(=O)c1c(NC(=O)Cc2sc(N)nc2O)sc2CC(CCc12)C(C)(C)C InChI=1S/C19H25N3O4S2/c1-19(2,3)9-5-6-10-11(7-9)27-16(14(10)17(25)26-4)21-13(23)8-12-15(24)22-18(20)28-12/h9,24H,5-8H2,1-4H3,(H2,20,22)(H,21,23) CTMHEJWNXSAAHS-UHFFFAOYSA-N 88455 SMR000262113::methyl 2-[2-(2-azanyl-4-oxidanylidene-1,3-thiazol-5-yl)ethanoylamino]-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate::cid_4344962::methyl 2-[[2-(2-amino-4-oxo-1,3-thiazol-5-yl)acetyl]amino]-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate::MLS000394873::2-[[2-(2-amino-4-oxo-5-thiazolyl)-1-oxoethyl]amino]-6-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester::2-[[2-(2-amino-4-keto-2-thiazolin-5-yl)acetyl]amino]-6-tert-butyl-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid methyl ester Melanocortin receptor 4 Homo sapiens >89198 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88455&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899116 252660171 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192585 Clc1ccc(C=NNC2=Nc3cccc4cccc2c34)cc1 |w:6.6,t:8| InChI=1S/C18H12ClN3/c19-14-9-7-12(8-10-14)11-20-22-18-15-5-1-3-13-4-2-6-16(21-18)17(13)15/h1-11H,(H,21,22) XENULQMMYLDKJI-UHFFFAOYSA-N 88456 N-[(E)-(4-chlorophenyl)methylideneamino]benzo[cd]indol-2-amine::N-[(E)-(4-chlorophenyl)methylideneamino]-2-benzo[cd]indolamine::cid_6899633::SMR000261712::MLS000392852::benzo[cd]indol-2-yl-[(E)-(4-chlorobenzylidene)amino]amine Melanocortin receptor 4 Homo sapiens >89121 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88456 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88456&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6899633 252660172 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192586 Cc1ccc(Sc2ccc(NC(=O)CCl)cc2)cc1C InChI=1S/C16H16ClNOS/c1-11-3-6-15(9-12(11)2)20-14-7-4-13(5-8-14)18-16(19)10-17/h3-9H,10H2,1-2H3,(H,18,19) ORXIIDGKDCBEGL-UHFFFAOYSA-N 70854 SMR000249604::2-chloro-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]acetamide::2-chloranyl-N-[4-(3,4-dimethylphenyl)sulfanylphenyl]ethanamide::MLS000334846::cid_2446553::2-chloro-N-[4-[(3,4-dimethylphenyl)thio]phenyl]acetamide Melanocortin receptor 4 Homo sapiens >89179 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70854 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70854&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2446553 252648680 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192587 Clc1ccccc1C=NNC1=Nc2cccc3cccc1c23 |w:8.9,t:11| InChI=1S/C18H12ClN3/c19-15-9-2-1-5-13(15)11-20-22-18-14-8-3-6-12-7-4-10-16(21-18)17(12)14/h1-11H,(H,21,22) GWWLAHNKGIJBJK-UHFFFAOYSA-N 43425 N-[(2-chlorophenyl)methylideneamino]-2-benzo[cd]indolamine::benzo[cd]indol-2-yl-[(E)-(2-chlorobenzylidene)amino]amine::N-[(2-chlorophenyl)methylideneamino]benzo[cd]indol-2-amine::MLS000392773::cid_2315072::SMR000261714::benzo[cd]indol-2-yl-[(2-chlorobenzylidene)amino]amine Melanocortin receptor 4 Homo sapiens >89263 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43425 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43425&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6899625 252624106 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192588 FC(F)Sc1ccc2nc(NC(=O)c3ccc(NS(=O)(=O)c4ccc(F)c(F)c4)cc3)sc2c1 InChI=1S/C21H13F4N3O3S3/c22-15-7-6-14(10-16(15)23)34(30,31)28-12-3-1-11(2-4-12)19(29)27-21-26-17-8-5-13(32-20(24)25)9-18(17)33-21/h1-10,20,28H,(H,26,27,29) ICAKXFBXHQCVBO-UHFFFAOYSA-N 57718 SMR000243135::cid_2412414::N-[6-(difluoromethylsulfanyl)-1,3-benzothiazol-2-yl]-4-[(3,4-difluorophenyl)sulfonylamino]benzamide::MLS000408886::N-[6-[bis(fluoranyl)methylsulfanyl]-1,3-benzothiazol-2-yl]-4-[[3,4-bis(fluoranyl)phenyl]sulfonylamino]benzamide::N-[6-(difluoromethylthio)-1,3-benzothiazol-2-yl]-4-[(3,4-difluorophenyl)sulfonylamino]benzamide Melanocortin receptor 4 Homo sapiens >89165 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57718 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57718&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2412414 252637638 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192589 [#6]-[#6]-[#8]-[#6](=O)-[#6](=[#6]\[#7]-c1ccc2n(nnc2c1)-c1ccc(Cl)cc1)\[#6](=O)-[#8]-[#6]-[#6] InChI=1S/C20H7ClN4O4/c1-3-28-19(26)16(20(27)29-4-2)12-22-14-7-10-18-17(11-14)23-24-25(18)15-8-5-13(21)6-9-15/h5-11H PPMQWLLCAMKGKL-UHFFFAOYSA-N 88458 MLS000698359::2-[[[1-(4-chlorophenyl)-5-benzotriazolyl]amino]methylidene]propanedioic acid diethyl ester::SMR000224928::diethyl 2-[[[1-(4-chlorophenyl)benzotriazol-5-yl]amino]methylidene]propanedioate::diethyl 2-({[1-(4-chlorophenyl)-1H-1,2,3-benzotriazol-5-yl]amino}methylene)malonate::cid_1827509::2-[[[1-(4-chlorophenyl)benzotriazol-5-yl]amino]methylene]malonic acid diethyl ester Melanocortin receptor 4 Homo sapiens >89215 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88458 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88458&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1827509 252660173 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192590 OC1(CC(=NN1C(=O)c1ccc(COc2ccc(Br)cc2)o1)C(F)F)C(F)F |c:3| InChI=1S/C17H13BrF4N2O4/c18-9-1-3-10(4-2-9)27-8-11-5-6-13(28-11)15(25)24-17(26,16(21)22)7-12(23-24)14(19)20/h1-6,14,16,26H,7-8H2 QDVNZAVAXSQBKM-UHFFFAOYSA-N 45268 SMR000228245::[3,5-bis[bis(fluoranyl)methyl]-5-oxidanyl-4H-pyrazol-1-yl]-[5-[(4-bromanylphenoxy)methyl]furan-2-yl]methanone::[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[5-[(4-bromophenoxy)methyl]furan-2-yl]methanone::MLS000698623::[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[5-[(4-bromophenoxy)methyl]-2-furanyl]methanone::1-{5-[(4-bromophenoxy)methyl]-2-furoyl}-3,5-bis(difluoromethyl)-4,5-dihydro-1H-pyrazol-5-ol::cid_4080428::[3,5-bis(difluoromethyl)-5-hydroxy-2-pyrazolin-1-yl]-[5-[(4-bromophenoxy)methyl]-2-furyl]methanone Melanocortin receptor 4 Homo sapiens >89179 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=45268 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=45268&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4080428 252625870 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192591 COc1ccc(\C=N\NC(=O)c2ccc(COc3ccccc3Cl)o2)c(OC)c1C InChI=1S/C22H21ClN2O5/c1-14-18(27-2)10-8-15(21(14)28-3)12-24-25-22(26)20-11-9-16(30-20)13-29-19-7-5-4-6-17(19)23/h4-12H,13H2,1-3H3,(H,25,26) ALSZPRQIWXWJGV-UHFFFAOYSA-N 88459 SMR000227699::MLS000699691::5-[(2-chlorophenoxy)methyl]-N-[(E)-(2,4-dimethoxy-3-methylphenyl)methylideneamino]furan-2-carboxamide::5-[(2-chlorophenoxy)methyl]-N'-(2,4-dimethoxy-3-methylbenzylidene)-2-furohydrazide::cid_6874399::5-[(2-chlorophenoxy)methyl]-N-[(E)-(2,4-dimethoxy-3-methylphenyl)methylideneamino]-2-furancarboxamide::5-[(2-chloranylphenoxy)methyl]-N-[(E)-(2,4-dimethoxy-3-methyl-phenyl)methylideneamino]furan-2-carboxamide::5-[(2-chlorophenoxy)methyl]-N-[(E)-(2,4-dimethoxy-3-methyl-benzylidene)amino]-2-furamide Melanocortin receptor 4 Homo sapiens >89207 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88459 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88459&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6874399 252660174 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192592 CCOc1cc(CNCCc2c[nH]c3ccccc23)cc(Cl)c1OCC InChI=1S/C21H25ClN2O2/c1-3-25-20-12-15(11-18(22)21(20)26-4-2)13-23-10-9-16-14-24-19-8-6-5-7-17(16)19/h5-8,11-12,14,23-24H,3-4,9-10,13H2,1-2H3 APABSGRYLLJSEU-UHFFFAOYSA-N 88460 MLS000698493::N-[(3-chloro-4,5-diethoxyphenyl)methyl]-2-(1H-indol-3-yl)ethanamine::N-[(3-chloranyl-4,5-diethoxy-phenyl)methyl]-2-(1H-indol-3-yl)ethanamine::N-(3-chloro-4,5-diethoxybenzyl)-N-[2-(1H-indol-3-yl)ethyl]amine::cid_1818022::SMR000228921::(3-chloro-4,5-diethoxy-benzyl)-[2-(1H-indol-3-yl)ethyl]amine Melanocortin receptor 4 Homo sapiens >89201 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88460 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88460&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1818022 252660175 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192593 Cc1ccc(NC(=O)c2ccccc2OCC(=O)c2ccc(F)cc2)cc1 InChI=1S/C22H18FNO3/c1-15-6-12-18(13-7-15)24-22(26)19-4-2-3-5-21(19)27-14-20(25)16-8-10-17(23)11-9-16/h2-13H,14H2,1H3,(H,24,26) IUSVXDMKTLXCLM-UHFFFAOYSA-N 88461 2-[2-(4-fluorophenyl)-2-oxidanylidene-ethoxy]-N-(4-methylphenyl)benzamide::cid_1218653::2-[2-(4-fluorophenyl)-2-oxoethoxy]-N-(4-methylphenyl)benzamide::SMR000227067::MLS000701771::2-[2-(4-fluorophenyl)-2-keto-ethoxy]-N-(p-tolyl)benzamide Melanocortin receptor 4 Homo sapiens >89235 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88461 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88461&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1218653 252660176 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192594 O=C(CCN1C(=S)S\C(=C/C=C/c2ccccc2)C1=O)Nc1cccnc1 InChI=1S/C20H17N3O2S2/c24-18(22-16-9-5-12-21-14-16)11-13-23-19(25)17(27-20(23)26)10-4-8-15-6-2-1-3-7-15/h1-10,12,14H,11,13H2,(H,22,24) CJWHICZIIUVMSL-UHFFFAOYSA-N 88462 MLS000663977::3-[4-oxo-5-(3-phenyl-2-propen-1-ylidene)-2-thioxo-1,3-thiazolidin-3-yl]-N-3-pyridinylpropanamide::3-[(5Z)-4-oxidanylidene-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-pyridin-3-yl-propanamide::3-[(5Z)-4-oxo-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-3-thiazolidinyl]-N-(3-pyridinyl)propanamide::3-[(5Z)-4-oxo-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-pyridin-3-ylpropanamide::cid_1321377::SMR000270595::3-[(5Z)-4-keto-5-[(E)-3-phenylprop-2-enylidene]-2-thioxo-thiazolidin-3-yl]-N-(3-pyridyl)propionamide Melanocortin receptor 4 Homo sapiens >89223 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88462 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88462&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1321377 252660177 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192595 COc1cc(NC(=O)COc2ccccc2[N+]([O-])=O)ccc1NC(=O)c1cccs1 InChI=1S/C20H17N3O6S/c1-28-17-11-13(8-9-14(17)22-20(25)18-7-4-10-30-18)21-19(24)12-29-16-6-3-2-5-15(16)23(26)27/h2-11H,12H2,1H3,(H,21,24)(H,22,25) DRIUVIBYLSWTGA-UHFFFAOYSA-N 55687 SMR000296671::cid_2237020::N-(2-methoxy-4-{[(2-nitrophenoxy)acetyl]amino}phenyl)-2-thiophenecarboxamide::N-[2-methoxy-4-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]phenyl]-2-thiophenecarboxamide::N-[2-methoxy-4-[2-(2-nitrophenoxy)ethanoylamino]phenyl]thiophene-2-carboxamide::MLS000679820::N-[2-methoxy-4-[[2-(2-nitrophenoxy)acetyl]amino]phenyl]thiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens >89203 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55687 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55687&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2237020 252635678 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192596 COc1cccc(CC2(CO)CCCN(Cc3[nH]c4ccc(C)cc4c3C)C2)c1 InChI=1S/C25H32N2O2/c1-18-8-9-23-22(12-18)19(2)24(26-23)15-27-11-5-10-25(16-27,17-28)14-20-6-4-7-21(13-20)29-3/h4,6-9,12-13,26,28H,5,10-11,14-17H2,1-3H3 FLBXKEKDPVBZPV-UHFFFAOYSA-N 88463 cid_16189221::[1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol::[1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-(3-methoxybenzyl)piperidin-3-yl]methanol::MLS000731927::[1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-[(3-methoxyphenyl)methyl]-3-piperidinyl]methanol::SMR000316058::[1-[(3,5-dimethyl-1H-indol-2-yl)methyl]-3-m-anisyl-3-piperidyl]methanol Melanocortin receptor 4 Homo sapiens >89189 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88463 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88463&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16189221 252660178 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192597 CC1(C)Oc2ccc3ccc(=O)oc3c2C(=CNc2ccc(O)cc2)C1=O |w:16.18| InChI=1S/C21H17NO5/c1-21(2)20(25)15(11-22-13-5-7-14(23)8-6-13)18-16(27-21)9-3-12-4-10-17(24)26-19(12)18/h3-11,22-23H,1-2H3 SLVFFRIZRCDEST-UHFFFAOYSA-N 88464 SMR000298918::(10Z)-10-[[(4-hydroxyphenyl)amino]methylidene]-8,8-dimethyl-pyrano[2,3-f]chromene-2,9-dione::MLS000690659::10-{[(4-hydroxyphenyl)amino]methylene}-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromene-2,9(10H)-dione::(10Z)-10-[(4-hydroxyanilino)methylidene]-8,8-dimethylpyrano[2,3-f]chromene-2,9-dione::(10Z)-10-[(4-hydroxyanilino)methylidene]-8,8-dimethylpyrano[2,3-f][1]benzopyran-2,9-dione::cid_2295134::(10Z)-10-[(4-hydroxyanilino)methylene]-8,8-dimethyl-pyrano[2,3-f]chromene-2,9-quinone Melanocortin receptor 4 Homo sapiens >89181 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88464&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2295134 252660179 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192598 Cc1c(CN2CCC(CO)(CCOc3ccccc3)CC2)[nH]c2c(Cl)cccc12 InChI=1S/C24H29ClN2O2/c1-18-20-8-5-9-21(25)23(20)26-22(18)16-27-13-10-24(17-28,11-14-27)12-15-29-19-6-3-2-4-7-19/h2-9,26,28H,10-17H2,1H3 BOBHPMQFFUSAAV-UHFFFAOYSA-N 68112 [1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)piperidin-4-yl]methanol::[1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanol::[1-[(7-chloranyl-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)piperidin-4-yl]methanol::SMR000316550::MLS000732248::cid_16190594::[1-[(7-chloro-3-methyl-1H-indol-2-yl)methyl]-4-(2-phenoxyethyl)-4-piperidyl]methanol Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68112 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68112&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16190594 252646390 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192599 Cc1ccc(cc1)C1=NN(C(C1)c1ccccc1O)C(=O)c1cccs1 |t:8| InChI=1S/C21H18N2O2S/c1-14-8-10-15(11-9-14)17-13-18(16-5-2-3-6-19(16)24)23(22-17)21(25)20-7-4-12-26-20/h2-12,18,24H,13H2,1H3 BFOMBLPFIDOMPL-UHFFFAOYSA-N 68113 MLS000690759::SMR000301193::[3-(2-hydroxyphenyl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone::2-[3-(4-methylphenyl)-1-(2-thienylcarbonyl)-4,5-dihydro-1H-pyrazol-5-yl]phenol::cid_2988713::[3-(2-hydroxyphenyl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-thiophen-2-yl-methanone::[5-(2-hydroxyphenyl)-3-(p-tolyl)-2-pyrazolin-1-yl]-(2-thienyl)methanone Melanocortin receptor 4 Homo sapiens >89194 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68113 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68113&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2988713 252646391 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192600 CCCCCCCCCCCCOCn1c[n+](C)c2ccccc12 InChI=1S/C21H35N2O/c1-3-4-5-6-7-8-9-10-11-14-17-24-19-23-18-22(2)20-15-12-13-16-21(20)23/h12-13,15-16,18H,3-11,14,17,19H2,1-2H3/q+1 LZGJHLXODMHFTH-UHFFFAOYSA-N 55756 1-(dodecoxymethyl)-3-methyl-benzimidazol-3-ium;chloride::cid_16192647::MLS000687707::SMR000283698::1-(dodecoxymethyl)-3-methylbenzimidazol-3-ium;chloride::1-(lauryloxymethyl)-3-methyl-benzimidazol-3-ium;chloride Melanocortin receptor 4 Homo sapiens >89210 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55756 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55756&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3113087 252635746 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192601 O=C(CCN1C(=S)S\C(=C/C=C/c2ccccc2)C1=O)Nc1ccccn1 InChI=1S/C20H17N3O2S2/c24-18(22-17-11-4-5-13-21-17)12-14-23-19(25)16(27-20(23)26)10-6-9-15-7-2-1-3-8-15/h1-11,13H,12,14H2,(H,21,22,24) CZKNMUIYWUQMIL-UHFFFAOYSA-N 88465 3-[(5Z)-4-oxo-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-3-thiazolidinyl]-N-(2-pyridinyl)propanamide::3-[(5Z)-4-oxo-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-pyridin-2-ylpropanamide::cid_1321526::SMR000270610::3-[4-oxo-5-(3-phenyl-2-propen-1-ylidene)-2-thioxo-1,3-thiazolidin-3-yl]-N-2-pyridinylpropanamide::MLS000663996::3-[(5Z)-4-oxidanylidene-5-[(E)-3-phenylprop-2-enylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-pyridin-2-yl-propanamide::3-[(5Z)-4-keto-5-[(E)-3-phenylprop-2-enylidene]-2-thioxo-thiazolidin-3-yl]-N-(2-pyridyl)propionamide Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88465 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88465&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1321526 252660180 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192602 [H]C12CC3([H])CC(C)(C1)CC(CC(=O)OCCc1sc[n+](CC(=O)c4ccccc4)c1C)(C2)C3 |TLB:5:3:32:6.9.8,THB:7:6:32:3.33.2,5:6:32:3.33.2,2:3:9:1.32.8| 78766 MLS000717822::cid_2884056::2-(4-methyl-3-phenacyl-1,3-thiazol-3-ium-5-yl)ethyl 2-(3-methyl-1-adamantyl)acetate;bromide::2-(3-methyl-1-adamantyl)acetic acid 2-(4-methyl-3-phenacyl-5-thiazol-3-iumyl)ethyl ester;bromide::2-(4-methyl-3-phenacyl-1,3-thiazol-3-ium-5-yl)ethyl 2-(3-methyl-1-adamantyl)ethanoate;bromide::SMR000279190::2-(3-methyl-1-adamantyl)acetic acid 2-(4-methyl-3-phenacyl-thiazol-3-ium-5-yl)ethyl ester;bromide Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78766 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78766&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2884057 252655508 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192603 CCN1\C(Sc2cc(C)c(C)cc12)=C\c1ccc2cc(C)ccc2[n+]1CC InChI=1S/C24H27N2S/c1-6-25-20(10-9-19-12-16(3)8-11-21(19)25)15-24-26(7-2)22-13-17(4)18(5)14-23(22)27-24/h8-15H,6-7H2,1-5H3/q+1 LHQFSVNOINPHTO-UHFFFAOYSA-N 51840 (2Z)-3-ethyl-2-[(1-ethyl-6-methyl-quinolin-1-ium-2-yl)methylidene]-5,6-dimethyl-1,3-benzothiazole;iodide::SMR000285129::(2Z)-3-ethyl-2-[(1-ethyl-6-methyl-2-quinolin-1-iumyl)methylidene]-5,6-dimethyl-1,3-benzothiazole;iodide::MLS000692767::(2Z)-3-ethyl-2-[(1-ethyl-6-methylquinolin-1-ium-2-yl)methylidene]-5,6-dimethyl-1,3-benzothiazole;iodide::cid_16192804::(2Z)-3-ethyl-2-[(1-ethyl-6-methyl-quinolin-1-ium-2-yl)methylene]-5,6-dimethyl-1,3-benzothiazole;iodide Melanocortin receptor 4 Homo sapiens >3304 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51840 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51840&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5767627 252632018 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192604 COc1ccc(CNCCc2ccc(Cl)cc2)cc1OCc1ccccc1 InChI=1S/C23H24ClNO2/c1-26-22-12-9-20(15-23(22)27-17-19-5-3-2-4-6-19)16-25-14-13-18-7-10-21(24)11-8-18/h2-12,15,25H,13-14,16-17H2,1H3 BZKFKMJKMGZZKC-UHFFFAOYSA-N 88466 SMR000267764::N-[3-(benzyloxy)-4-methoxybenzyl]-2-(4-chlorophenyl)ethanamine::cid_2169083::2-(4-chlorophenyl)-N-[(4-methoxy-3-phenylmethoxy-phenyl)methyl]ethanamine::2-(4-chlorophenyl)-N-[(4-methoxy-3-phenylmethoxyphenyl)methyl]ethanamine::MLS000681370::(3-benzoxy-4-methoxy-benzyl)-[2-(4-chlorophenyl)ethyl]amine Melanocortin receptor 4 Homo sapiens >9912 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88466 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88466&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2169083 252660181 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192605 Cc1ccc(cc1)C(=O)NCCNc1nc2cc(C)c(C)cc2cc1C InChI=1S/C22H25N3O/c1-14-5-7-18(8-6-14)22(26)24-10-9-23-21-17(4)12-19-11-15(2)16(3)13-20(19)25-21/h5-8,11-13H,9-10H2,1-4H3,(H,23,25)(H,24,26) INLVGDOETIFUOM-UHFFFAOYSA-N 88467 4-methyl-N-[2-[(3,6,7-trimethylquinolin-2-yl)amino]ethyl]benzamide::cid_3206667::4-methyl-N-[2-[(3,6,7-trimethyl-2-quinolinyl)amino]ethyl]benzamide::SMR000284360::MLS000688428::4-methyl-N-[2-[(3,6,7-trimethyl-2-quinolyl)amino]ethyl]benzamide Melanocortin receptor 4 Homo sapiens >89241 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88467 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88467&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3206667 252660182 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192606 Cc1cccc(C)c1-n1cccc1\C=C1/SC(=S)N(C1=O)c1cccc(c1)C(O)=O |(3.08,-1.79,;4.41,-2.56,;4.41,-4.1,;5.75,-4.87,;7.08,-4.1,;7.08,-2.56,;8.41,-1.79,;5.75,-1.79,;5.75,-.25,;4.5,.65,;4.98,2.12,;6.52,2.12,;6.99,.65,;8.46,.18,;9.6,1.21,;9.44,2.74,;10.85,3.37,;11.17,4.87,;11.88,2.22,;11.11,.89,;11.74,-.52,;13.41,2.38,;14.04,3.79,;15.57,3.95,;16.47,2.7,;15.85,1.3,;14.32,1.14,;16.75,.05,;18.28,.21,;16.13,-1.36,)| InChI=1S/C23H18N2O3S2/c1-14-6-3-7-15(2)20(14)24-11-5-10-17(24)13-19-21(26)25(23(29)30-19)18-9-4-8-16(12-18)22(27)28/h3-13H,1-2H3,(H,27,28) GYERWAQYRZSXRC-UHFFFAOYSA-N 57887 3-((5Z)-5-{[1-(2,6-dimethylphenyl)-1H-pyrrol-2-yl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)benzoic acid::3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid::3-[(5Z)-5-[[1-(2,6-dimethylphenyl)-2-pyrrolyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzoic acid::SMR000314015::MLS000675293::3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid::cid_16194382::3-[(5Z)-5-[[1-(2,6-dimethylphenyl)pyrrol-2-yl]methylene]-4-keto-2-thioxo-thiazolidin-3-yl]benzoic acid Melanocortin receptor 4 Homo sapiens >89220 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57887 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57887&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194382 252637806 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192607 Cc1ccc(O)c(c1)C(=O)\C=C\c1ccc2OCCOc2c1 InChI=1S/C18H16O4/c1-12-2-5-15(19)14(10-12)16(20)6-3-13-4-7-17-18(11-13)22-9-8-21-17/h2-7,10-11,19H,8-9H2,1H3 JTRSQAFGGRNZFJ-UHFFFAOYSA-N 88468 (E)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one::(E)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(5-methyl-2-oxidanyl-phenyl)prop-2-en-1-one::SMR000312578::3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en- 1-one::(E)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(2-hydroxy-5-methylphenyl)-2-propen-1-one::cid_5709345::MLS000685614::(E)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(2-hydroxy-5-methyl-phenyl)prop-2-en-1-one Melanocortin receptor 4 Homo sapiens >89245 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88468 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88468&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5709345 252660183 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192608 CN(C)CCCN(C(=O)COc1ccc(Cl)cc1)c1nc2cc(C)cc(C)c2s1 InChI=1S/C22H26ClN3O2S/c1-15-12-16(2)21-19(13-15)24-22(29-21)26(11-5-10-25(3)4)20(27)14-28-18-8-6-17(23)7-9-18/h6-9,12-13H,5,10-11,14H2,1-4H3 HZJFUUXNALQFED-UHFFFAOYSA-N 88469 MLS000686138::cid_16194860::2-(4-chloranylphenoxy)-N-[3-(dimethylamino)propyl]-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)ethanamide;hydrochloride::SMR000324170::2-(4-chlorophenoxy)-N-[3-(dimethylamino)propyl]-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)acetamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88469 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88469&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194861 252660184 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192609 CN(C)CCCN(C(=O)c1ccc(Br)s1)c1nc2c(C)c(C)ccc2s1 InChI=1S/C19H22BrN3OS2/c1-12-6-7-14-17(13(12)2)21-19(26-14)23(11-5-10-22(3)4)18(24)15-8-9-16(20)25-15/h6-9H,5,10-11H2,1-4H3 OQRUBFMHLUDBBU-UHFFFAOYSA-N 84117 5-bromanyl-N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)thiophene-2-carboxamide;hydrochloride::SMR000324166::MLS000686133::5-bromo-N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide;hydrochloride::cid_16194866::5-bromo-N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)thiophene-2-carboxamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84117 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84117&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194867 252659281 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192610 CN(C)CCCN(C(=O)CN1C(=O)c2ccccc2C1=O)c1nc2c(C)c(C)ccc2s1 InChI=1S/C24H26N4O3S/c1-15-10-11-19-21(16(15)2)25-24(32-19)27(13-7-12-26(3)4)20(29)14-28-22(30)17-8-5-6-9-18(17)23(28)31/h5-6,8-11H,7,12-14H2,1-4H3 UHNOESRYDLOZSI-UHFFFAOYSA-N 88470 SMR000324167::cid_16194869::2-[1,3-bis(oxidanylidene)isoindol-2-yl]-N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)ethanamide;hydrochloride::N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)-2-(1,3-dioxo-2-isoindolyl)acetamide;hydrochloride::N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)-2-(1,3-dioxoisoindol-2-yl)acetamide;hydrochloride::MLS000686131::N-[3-(dimethylamino)propyl]-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)-2-phthalimido-acetamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89222 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88470 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88470&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194870 252660185 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192611 CN(C)CCCN(C(=O)c1ccc(Br)s1)c1nc2cc(C)cc(C)c2s1 InChI=1S/C19H22BrN3OS2/c1-12-10-13(2)17-14(11-12)21-19(26-17)23(9-5-8-22(3)4)18(24)15-6-7-16(20)25-15/h6-7,10-11H,5,8-9H2,1-4H3 XOAMMOVGHOZZSZ-UHFFFAOYSA-N 88471 SMR000324169::5-bromo-N-[3-(dimethylamino)propyl]-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide;hydrochloride::MLS000686140::5-bromanyl-N-[3-(dimethylamino)propyl]-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)thiophene-2-carboxamide;hydrochloride::cid_16194884::5-bromo-N-[3-(dimethylamino)propyl]-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)thiophene-2-carboxamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88471 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88471&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194885 252660186 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192612 COc1cccc2sc(nc12)N(CCCN(C)C)C(=O)C(c1ccccc1)c1ccccc1 InChI=1S/C27H29N3O2S/c1-29(2)18-11-19-30(27-28-25-22(32-3)16-10-17-23(25)33-27)26(31)24(20-12-6-4-7-13-20)21-14-8-5-9-15-21/h4-10,12-17,24H,11,18-19H2,1-3H3 KGHCKYAADOQTDL-UHFFFAOYSA-N 88472 N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)-2,2-diphenylacetamide;hydrochloride::SMR000324151::MLS000686127::N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)-2,2-diphenyl-ethanamide;hydrochloride::cid_16194897::N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)-2,2-diphenyl-acetamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88472 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88472&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194898 252660187 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192613 Nc1nccc(n1)-c1ccc(OCc2c(F)cccc2Cl)cc1 InChI=1S/C17H13ClFN3O/c18-14-2-1-3-15(19)13(14)10-23-12-6-4-11(5-7-12)16-8-9-21-17(20)22-16/h1-9H,10H2,(H2,20,21,22) LAMKPYKCCSEZKX-UHFFFAOYSA-N 88473 MLS000721597::cid_1472403::4-[4-[(2-chloranyl-6-fluoranyl-phenyl)methoxy]phenyl]pyrimidin-2-amine::SMR000335908::4-[4-[(2-chloro-6-fluorophenyl)methoxy]phenyl]pyrimidin-2-amine::4-[4-[(2-chloro-6-fluorophenyl)methoxy]phenyl]-2-pyrimidinamine::4-{4-[(2-chloro-6-fluorobenzyl)oxy]phenyl}-2-pyrimidinamine::[4-[4-(2-chloro-6-fluoro-benzyl)oxyphenyl]pyrimidin-2-yl]amine Melanocortin receptor 4 Homo sapiens >89278 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88473 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88473&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1472403 252660188 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192614 CCN1CCN(CCNC(=O)c2ccc(\C=C3/Sc4ccccc4N(Cc4ccccc4F)C3=O)cc2)CC1 InChI=1S/C31H33FN4O2S/c1-2-34-17-19-35(20-18-34)16-15-33-30(37)24-13-11-23(12-14-24)21-29-31(38)36(22-25-7-3-4-8-26(25)32)27-9-5-6-10-28(27)39-29/h3-14,21H,2,15-20,22H2,1H3,(H,33,37) LKWNQQVTFQKJHY-UHFFFAOYSA-N 55818 N-[2-(4-ethyl-1-piperazinyl)ethyl]-4-[(Z)-[4-[(2-fluorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]benzamide::N-[2-(4-ethylpiperazin-1-yl)ethyl]-4-[(Z)-[4-[(2-fluorophenyl)methyl]-3-oxo-1,4-benzothiazin-2-ylidene]methyl]benzamide::N-[2-(4-ethylpiperazin-1-yl)ethyl]-4-[(Z)-[4-[(2-fluorophenyl)methyl]-3-oxidanylidene-1,4-benzothiazin-2-ylidene]methyl]benzamide::MLS000730814::SMR000308989::cid_16195590::N-[2-(4-ethylpiperazin-1-yl)ethyl]-4-{(Z)-[4-(2-fluorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-ylidene]methyl}benzamide::N-[2-(4-ethylpiperazino)ethyl]-4-[(Z)-[4-(2-fluorobenzyl)-3-keto-1,4-benzothiazin-2-ylidene]methyl]benzamide Melanocortin receptor 4 Homo sapiens >89222 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55818 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55818&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16195590 252635807 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192615 CN(C)CCCNc1nn2c(nc3scc(-c4ccc(C)cc4)c3c2=O)c2ccccc12 InChI=1S/C25H25N5OS/c1-16-9-11-17(12-10-16)20-15-32-24-21(20)25(31)30-23(27-24)19-8-5-4-7-18(19)22(28-30)26-13-6-14-29(2)3/h4-5,7-12,15H,6,13-14H2,1-3H3,(H,26,28) QOPHDNPCVKIJEJ-UHFFFAOYSA-N 78825 MLS000517203::SMR000343327::cid_2132539 Melanocortin receptor 4 Homo sapiens >89176 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78825 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78825&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2132539 242053637 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192616 CC(C)C1CCC(C)CC1OC(=O)C[n+]1cc(-c2ccc(Cl)cc2)n2CCCCCc12 InChI=1S/C26H36ClN2O2/c1-18(2)22-13-8-19(3)15-24(22)31-26(30)17-28-16-23(20-9-11-21(27)12-10-20)29-14-6-4-5-7-25(28)29/h9-12,16,18-19,22,24H,4-8,13-15,17H2,1-3H3/q+1 OWJNNMGFSZEVIL-UHFFFAOYSA-N 88474 cid_16196192::(5-methyl-2-propan-2-yl-cyclohexyl) 2-[3-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-1-ium-1-yl]ethanoate;chloride::SMR000354352::MLS001018094::(5-methyl-2-propan-2-ylcyclohexyl) 2-[3-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-1-ium-1-yl]acetate;chloride::2-[3-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-1-ium-1-yl]acetic acid (5-methyl-2-propan-2-ylcyclohexyl) ester;chloride::2-[3-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-imidaz[1,2-a]azepin-1-ium-1-yl]acetic acid (2-isopropyl-5-methyl-cyclohexyl) ester;chloride Melanocortin receptor 4 Homo sapiens >9912 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88474 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88474&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3653153 252660189 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192617 CC(=O)Nc1ccc(cc1)-c1csc(NC(=O)Nc2ccccc2)n1 InChI=1S/C18H16N4O2S/c1-12(23)19-15-9-7-13(8-10-15)16-11-25-18(21-16)22-17(24)20-14-5-3-2-4-6-14/h2-11H,1H3,(H,19,23)(H2,20,21,22,24) AVSVJGAGDGCOFI-UHFFFAOYSA-N 88475 cid_2554360::N-[4-[2-(phenylcarbamoylamino)-1,3-thiazol-4-yl]phenyl]ethanamide::N-[4-[2-(phenylcarbamoylamino)-1,3-thiazol-4-yl]phenyl]acetamide::N-[4-[2-[[anilino(oxo)methyl]amino]-4-thiazolyl]phenyl]acetamide::MLS001007754::SMR000384878::N-[4-[2-(phenylcarbamoylamino)thiazol-4-yl]phenyl]acetamide Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88475 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88475&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2554360 252660190 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192618 Oc1ccc(cc1)N1CCN(CC1)c1ncnc2sc(cc12)-c1ccccc1 InChI=1S/C22H20N4OS/c27-18-8-6-17(7-9-18)25-10-12-26(13-11-25)21-19-14-20(16-4-2-1-3-5-16)28-22(19)24-15-23-21/h1-9,14-15,27H,10-13H2 OLNNUFFSADAYPY-UHFFFAOYSA-N 50563 4-[4-(6-phenyl-4-thieno[2,3-d]pyrimidinyl)-1-piperazinyl]phenol::SMR000369638::MLS000760381::cid_2495129::4-[4-(6-phenylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]phenol::4-[4-(6-phenylthieno[2,3-d]pyrimidin-4-yl)piperazino]phenol Melanocortin receptor 4 Homo sapiens >89178 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50563 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50563&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2495129 252630822 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192619 [#6]-[#8]-c1cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1-[#6](=O)-[#6]-[#6]-c1ccc(-[#8])cc1 InChI=1S/C21H5O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h5-6,8-9,12H QMTRRSDEVOXVDU-UHFFFAOYSA-N 76566 SMR000440746::3-(4-hydroxyphenyl)-1-[6-methoxy-3-(3-methylbut-2-enyl)-2,4-bis(oxidanyl)phenyl]propan-1-one::cid_10450920::1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)-1-propanone::MLS000863606::1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one Melanocortin receptor 4 Homo sapiens >89202 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76566 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76566&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 10450920 252653744 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192620 CCC(C)(C)c1ccc(OCCCC[n+]2cccc(C)c2C)c(c1)C(C)(C)CC InChI=1S/C27H42NO/c1-9-26(5,6)23-15-16-25(24(20-23)27(7,8)10-2)29-19-12-11-17-28-18-13-14-21(3)22(28)4/h13-16,18,20H,9-12,17,19H2,1-8H3/q+1 FBKDVLVCTRMCFG-UHFFFAOYSA-N 54364 MLS001030204::cid_16681765::1-[4-[2,4-bis(2-methylbutan-2-yl)phenoxy]butyl]-2,3-dimethyl-pyridin-1-ium;bromide::1-[4-[2,4-bis(2-methylbutan-2-yl)phenoxy]butyl]-2,3-dimethylpyridin-1-ium;bromide::SMR000427310::1-{4-[2,4-Bis-(1,1-dimethyl-propyl)-phenoxy]-butyl}-2,3-dimethyl-pyridinium::1-[4-(2,4-ditert-amylphenoxy)butyl]-2,3-dimethyl-pyridin-1-ium;bromide Melanocortin receptor 4 Homo sapiens >3304 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54364&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1621272 252634394 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192621 Cc1cc(C)c2nc(Nc3nc(cc(=O)[nH]3)-c3ccccc3)nc(C)c2c1 InChI=1S/C21H19N5O/c1-12-9-13(2)19-16(10-12)14(3)22-20(25-19)26-21-23-17(11-18(27)24-21)15-7-5-4-6-8-15/h4-11H,1-3H3,(H2,22,23,24,25,26,27) JIGWMNRWIILAAP-UHFFFAOYSA-N 88476 1,4-dioxane;6-phenyl-2-[(4,6,8-trimethyl-2-quinazolinyl)amino]-1H-pyrimidin-4-one::6-Phenyl-2-(4,6,8-trimethyl-quinazolin-2-ylamino)-pyrimidin-4-ol::cid_16682004::MLS000777863::SMR000414249::1,4-dioxane;6-phenyl-2-[(4,6,8-trimethylquinazolin-2-yl)amino]-1H-pyrimidin-4-one Melanocortin receptor 4 Homo sapiens >89200 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88476 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88476&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1002843 252660191 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192622 COc1cccc(CN=Nc2nc(nc3ccccc23)-c2cccnc2)c1O |w:9.9| InChI=1S/C21H17N5O2/c1-28-18-10-4-6-14(19(18)27)13-23-26-21-16-8-2-3-9-17(16)24-20(25-21)15-7-5-11-22-12-15/h2-12,27H,13H2,1H3 FKAUNFYJEBNUOU-UHFFFAOYSA-N 50627 (6E)-2-methoxy-6-[[[2-(3-pyridinyl)-4-quinazolinyl]hydrazo]methylidene]-1-cyclohexa-2,4-dienone::MLS000777524::SMR000413918::2-Methoxy-6-[(2-pyridin-3-yl-quinazolin-4-yl)-hydrazonomethyl]-phenol::(6E)-2-methoxy-6-[[2-(2-pyridin-3-ylquinazolin-4-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one::cid_5515318::(6E)-2-methoxy-6-[[N'-[2-(3-pyridyl)quinazolin-4-yl]hydrazino]methylene]cyclohexa-2,4-dien-1-one Melanocortin receptor 4 Homo sapiens >89200 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50627&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91896929 252630884 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192623 COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1 InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 BKRMCDAOAQWNTG-UHFFFAOYSA-N 50174412 CHEMBL19954::cid_72512::9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole9-OCH3-E::O-methylellipticine::9-methoxy ellipticine::9-methoxyellipticine::9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole Melanocortin receptor 4 Homo sapiens >89313 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174412 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174412&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 72512 104060230 CHEMBL19954 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192624 FC(F)(F)c1cccnc1Oc1ccc(cc1)C1=NCCS1 |t:19| InChI=1S/C15H11F3N2OS/c16-15(17,18)12-2-1-7-19-13(12)21-11-5-3-10(4-6-11)14-20-8-9-22-14/h1-7H,8-9H2 RBXFQDXHFYENKQ-UHFFFAOYSA-N 88477 SMR000461397::MLS000834881::cid_2744571::2-[4-[[3-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]-4,5-dihydrothiazole::2-(4-{[3-(trifluoromethyl)-2-pyridyl]oxy}phenyl)-4,5-dihydro-1,3-thiazole::2-[4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-4,5-dihydro-1,3-thiazole::2-[4-[[3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]-2-thiazoline Melanocortin receptor 4 Homo sapiens >89119 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88477 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88477&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2744571 252660192 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192625 CCCCCCCCCCOC(=O)Cn1c(COc2cccc(C)c2)[n+](C)c2ccccc12 InChI=1S/C28H39N2O3/c1-4-5-6-7-8-9-10-13-19-32-28(31)21-30-26-18-12-11-17-25(26)29(3)27(30)22-33-24-16-14-15-23(2)20-24/h11-12,14-18,20H,4-10,13,19,21-22H2,1-3H3/q+1 OLBHSOXHEMBKTO-UHFFFAOYSA-N 51900 MLS001207857::SMR000505012::1-Decyloxycarbonylmethyl-3-methyl-2-m-tolyloxymethyl-3H-benzoimidazol-1-ium::cid_23724249::decyl 2-[3-methyl-2-[(3-methylphenoxy)methyl]benzimidazol-3-ium-1-yl]ethanoate;chloride::2-[3-methyl-2-[(3-methylphenoxy)methyl]-1-benzimidazol-3-iumyl]acetic acid decyl ester;chloride::decyl 2-[3-methyl-2-[(3-methylphenoxy)methyl]benzimidazol-3-ium-1-yl]acetate;chloride::2-[3-methyl-2-[(3-methylphenoxy)methyl]benzimidazol-3-ium-1-yl]acetic acid decyl ester;chloride Melanocortin receptor 4 Homo sapiens >89176 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51900 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51900&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3092514 252632058 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192626 [#7]\[#6](-[#7])=[#7]\c1nc(-c2ccccc2)c2cc(Cl)ccc2n1 InChI=1S/C15H8ClN5/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)20-15(19-12)21-14(17)18/h1-8H ZKLXWPDFGYHVNG-UHFFFAOYSA-N 78962 2-(6-chloro-4-phenylquinazolin-2-yl)guanidine;hydrochloride::N-(6-Chloro-4-phenyl-quinazolin-2-yl)-guanidine::cid_24746808::SMR000518356::2-(6-chloro-4-phenyl-2-quinazolinyl)guanidine;hydrochloride::MLS001206456::2-(6-chloranyl-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride::2-(6-chloro-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride Melanocortin receptor 4 Homo sapiens >89249 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78962 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78962&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3145916 252655682 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192627 CCCCCCOc1ccc(cc1)C(C)=NNC1=NCCN1 |w:15.16,t:18| InChI=1S/C17H26N4O/c1-3-4-5-6-13-22-16-9-7-15(8-10-16)14(2)20-21-17-18-11-12-19-17/h7-10H,3-6,11-13H2,1-2H3,(H2,18,19,21) XJECEHJPTJMFPN-UHFFFAOYSA-N 78963 [(E)-1-(4-hexoxyphenyl)ethylideneamino]-(2-imidazolin-2-yl)amine::MLS001205948::N-[1-(4-hexoxyphenyl)ethylideneamino]-4,5-dihydro-1H-imidazol-2-amine::N-(4,5-Dihydro-1H-imidazol-2-yl)-N'-[1-(4-hexyloxy-phenyl)-ethylidene]-hydrazine::cid_3098371::SMR000513357::[1-(4-hexoxyphenyl)ethylideneamino]-(2-imidazolin-2-yl)amine Melanocortin receptor 4 Homo sapiens >89131 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78963 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78963&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9590747 252655683 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192628 CCCCCCCCCCOC(=O)Cn1c(COc2ccc(OC)cc2)[n+](C)c2ccccc12 InChI=1S/C28H39N2O4/c1-4-5-6-7-8-9-10-13-20-33-28(31)21-30-26-15-12-11-14-25(26)29(2)27(30)22-34-24-18-16-23(32-3)17-19-24/h11-12,14-19H,4-10,13,20-22H2,1-3H3/q+1 YNPKYHWFTVWXMK-UHFFFAOYSA-N 51903 SMR000505011::MLS001202706::cid_24746791::decyl 2-[2-[(4-methoxyphenoxy)methyl]-3-methylbenzimidazol-3-ium-1-yl]acetate;chloride::1-Decyloxycarbonylmethyl-2-(4-methoxy-phenoxymethyl)-3-methyl-3H-benzoimidazol-1-ium::decyl 2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-benzimidazol-3-ium-1-yl]ethanoate;chloride::2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-1-benzimidazol-3-iumyl]acetic acid decyl ester;chloride::2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-benzimidazol-3-ium-1-yl]acetic acid decyl ester;chloride Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51903 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51903&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3092507 252632061 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192629 COc1ccc(cc1)-c1oc2ccc(cc2c1C#CC1(O)CCCCC1)-c1ccc2OCOc2c1 InChI=1S/C30H26O5/c1-32-23-9-5-20(6-10-23)29-24(13-16-30(31)14-3-2-4-15-30)25-17-21(7-11-26(25)35-29)22-8-12-27-28(18-22)34-19-33-27/h5-12,17-18,31H,2-4,14-15,19H2,1H3 WEZSIGWUVUZJTJ-UHFFFAOYSA-N 88479 SMR000526356::MLS001144050::1-[2-[5-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]ethynyl]cyclohexan-1-ol::cid_24747934::1-[2-[5-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-3-benzofuranyl]ethynyl]-1-cyclohexanol::1-[2-[5-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)benzofuran-3-yl]ethynyl]cyclohexanol Melanocortin receptor 4 Homo sapiens >89209 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88479 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88479&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 24747934 252660193 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192630 Cc1ccc(CN2CCC(CC2)c2cc(n[nH]2)-c2ccc(Cl)cc2)cc1 InChI=1S/C22H24ClN3/c1-16-2-4-17(5-3-16)15-26-12-10-19(11-13-26)22-14-21(24-25-22)18-6-8-20(23)9-7-18/h2-9,14,19H,10-13,15H2,1H3,(H,24,25) RSYCVESFMFLJAO-UHFFFAOYSA-N 88480 MLS001165200::4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-[(4-methylphenyl)methyl]piperidine::SMR000549717::4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]-1-(4-methylbenzyl)piperidine::cid_3578737::4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-(4-methylbenzyl)piperidine Melanocortin receptor 4 Homo sapiens >89205 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88480 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88480&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3578737 252660194 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192631 OC(CNCCc1ccc(cc1)C(F)(F)F)COC(c1ccccc1)c1ccccc1 InChI=1S/C25H26F3NO2/c26-25(27,28)22-13-11-19(12-14-22)15-16-29-17-23(30)18-31-24(20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-14,23-24,29-30H,15-18H2 PUANSOTUBGWNQQ-UHFFFAOYSA-N 61579 1-(diphenylmethyl)oxy-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol;ethanedioic acid::cid_16245312::1-(diphenylmethyl)oxy-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]-2-propanol;oxalic acid::SMR000588059::MLS001174457::1-benzhydryloxy-3-[2-[4-(trifluoromethyl)phenyl]ethylamino]propan-2-ol;oxalic acid Melanocortin receptor 4 Homo sapiens >89167 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61579 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61579&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5162254 252640732 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192632 COc1cc2nc(Nc3ccc(C)c(Cl)c3)nc(N)c2cc1OC InChI=1S/C17H17ClN4O2/c1-9-4-5-10(6-12(9)18)20-17-21-13-8-15(24-3)14(23-2)7-11(13)16(19)22-17/h4-8H,1-3H3,(H3,19,20,21,22) WFMOFGWKZAWYQG-UHFFFAOYSA-N 79016 2-N-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine;hydrochloride::N2-(3-chloranyl-4-methyl-phenyl)-6,7-dimethoxy-quinazoline-2,4-diamine;hydrochloride::SMR000560136::MLS001199666::N2-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine;hydrochloride::N~2~-(3-chloro-4-methylphenyl)-6,7-dimethoxyquinazoline-2,4-diamine::cid_24762072::(4-amino-6,7-dimethoxy-quinazolin-2-yl)-(3-chloro-4-methyl-phenyl)amine;hydrochloride Melanocortin receptor 4 Homo sapiens >89217 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79016 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79016&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 22432685 252655733 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192633 CC(C)c1ccc(NS(=O)(=O)c2ccc(cc2)-n2cccn2)cc1 InChI=1S/C18H19N3O2S/c1-14(2)15-4-6-16(7-5-15)20-24(22,23)18-10-8-17(9-11-18)21-13-3-12-19-21/h3-14,20H,1-2H3 SHLCVQZQYIIGBA-UHFFFAOYSA-N 88481 MLS001126243::N-(4-propan-2-ylphenyl)-4-pyrazol-1-yl-benzenesulfonamide::SMR000629448::cid_6624952::N-(4-propan-2-ylphenyl)-4-(1-pyrazolyl)benzenesulfonamide::N-(4-propan-2-ylphenyl)-4-pyrazol-1-ylbenzenesulfonamide::N-p-cumenyl-4-pyrazol-1-yl-benzenesulfonamide Melanocortin receptor 4 Homo sapiens >89184 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88481 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88481&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6624952 252660195 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192634 CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)C(=O)c4c[nH]c5ccccc45)c3)cc2C(F)(F)F)CC1 InChI=1S/C32H32F3N5O3/c1-3-39-12-14-40(15-13-39)19-22-10-11-23(17-26(22)32(33,34)35)37-30(42)21-9-8-20(2)28(16-21)38-31(43)29(41)25-18-36-27-7-5-4-6-24(25)27/h4-11,16-18,36H,3,12-15,19H2,1-2H3,(H,37,42)(H,38,43) BQRFGIIHXOVNDN-UHFFFAOYSA-N 51933 N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-4-methyl-benzamide::SMR000718306::MLS000911609::N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxoacetyl]amino]-4-methylbenzamide;2,2,2-trifluoroacetic acid::N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-1,2-dioxoethyl]amino]-4-methylbenzamide;2,2,2-trifluoroacetic acid::cid_24816489::N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxidanylidene-ethanoyl]amino]-4-methyl-benzamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-4-methyl-benzamide;2,2,2-trifluoroacetic acid Melanocortin receptor 4 Homo sapiens >89183 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51933 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51933&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16745799 252632090 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192635 CC(=NNC(=O)COc1cccc2ccccc12)c1cccs1 |w:2.2| InChI=1S/C18H16N2O2S/c1-13(17-10-5-11-23-17)19-20-18(21)12-22-16-9-4-7-14-6-2-3-8-15(14)16/h2-11H,12H2,1H3,(H,20,21) ZZMKSPISXRSTPS-UHFFFAOYSA-N 88482 cid_9585284::2-naphthalen-1-yloxy-N-[(E)-1-thiophen-2-ylethylideneamino]acetamide::2-naphthalen-1-yloxy-N-[(E)-1-thiophen-2-ylethylideneamino]ethanamide::SMR000658660::MLS001123654::2-(1-naphthalenyloxy)-N-[(E)-1-thiophen-2-ylethylideneamino]acetamide::2-(1-naphthoxy)-N-[(E)-1-(2-thienyl)ethylideneamino]acetamide Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88482&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9585284 252660196 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192636 CCCCCCCNC(=O)C1(CC2CC(=NO2)c2ccc(Cl)cc2)CCNCC1 |c:14| InChI=1S/C23H34ClN3O2/c1-2-3-4-5-6-13-26-22(28)23(11-14-25-15-12-23)17-20-16-21(27-29-20)18-7-9-19(24)10-8-18/h7-10,20,25H,2-6,11-17H2,1H3,(H,26,28) OYNKLJWZPHDEGJ-UHFFFAOYSA-N 79115 MLS001144009::SMR000718502::4-[[3-(4-chlorophenyl)-4,5-dihydroisoxazol-5-yl]methyl]-N-heptyl-4-piperidinecarboxamide::4-[[3-(4-chlorophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl]-N-heptyl-piperidine-4-carboxamide::cid_24818153::4-[[3-(4-chlorophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl]-N-heptylpiperidine-4-carboxamide::4-[[3-(4-chlorophenyl)-2-isoxazolin-5-yl]methyl]-N-heptyl-isonipecotamide Melanocortin receptor 4 Homo sapiens >89198 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79115 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79115&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 24818153 252655830 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192637 Cc1cc(NC(=O)c2cncc(Br)c2)ccc1NC(=O)c1cc2ccccc2o1 InChI=1S/C22H16BrN3O3/c1-13-8-17(25-21(27)15-9-16(23)12-24-11-15)6-7-18(13)26-22(28)20-10-14-4-2-3-5-19(14)29-20/h2-12H,1H3,(H,25,27)(H,26,28) IXSJMTMWMIUFQH-UHFFFAOYSA-N 88483 N-[4-(1-benzofuran-2-carbonylamino)-3-methylphenyl]-5-bromopyridine-3-carboxamide::cid_2992593::N-[4-[[2-benzofuranyl(oxo)methyl]amino]-3-methylphenyl]-5-bromo-3-pyridinecarboxamide::MLS001162536::SMR000670354::N-[4-(1-benzofuran-2-ylcarbonylamino)-3-methyl-phenyl]-5-bromanyl-pyridine-3-carboxamide::N-[4-(benzofuran-2-carbonylamino)-3-methyl-phenyl]-5-bromo-nicotinamide Melanocortin receptor 4 Homo sapiens >89214 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88483&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2992593 252660197 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192638 CCCCNc1c(nc2ccc(C)cn12)-c1cccc(c1)-c1cc(cs1)C(C)=O InChI=1S/C24H25N3OS/c1-4-5-11-25-24-23(26-22-10-9-16(2)14-27(22)24)19-8-6-7-18(12-19)21-13-20(15-29-21)17(3)28/h6-10,12-15,25H,4-5,11H2,1-3H3 LMCAYKBLZJXPDW-UHFFFAOYSA-N 88484 SMR000814671::1-[5-[3-[3-(butylamino)-6-methylimidazo[1,2-a]pyridin-2-yl]phenyl]thiophen-3-yl]ethanone;2,2,2-trifluoroacetic acid::1-[5-[3-[3-(butylamino)-6-methyl-imidazo[1,2-a]pyridin-2-yl]phenyl]thiophen-3-yl]ethanone;2,2,2-tris(fluoranyl)ethanoic acid::1-[5-[3-[3-(butylamino)-6-methyl-2-imidazo[1,2-a]pyridinyl]phenyl]-3-thiophenyl]ethanone;2,2,2-trifluoroacetic acid::cid_24891816::MLS001066062::1-[5-[3-[3-(butylamino)-6-methyl-imidazo[1,2-a]pyridin-2-yl]phenyl]-3-thienyl]ethanone;2,2,2-trifluoroacetic acid Melanocortin receptor 4 Homo sapiens >89164 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88484&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 24891817 252660198 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192639 COc1cccc(\C=C2\SC(=S)N(CCCC(=O)Nc3ccc(O)cc3)C2=O)c1 InChI=1S/C21H20N2O4S2/c1-27-17-5-2-4-14(12-17)13-18-20(26)23(21(28)29-18)11-3-6-19(25)22-15-7-9-16(24)10-8-15/h2,4-5,7-10,12-13,24H,3,6,11H2,1H3,(H,22,25) CATWVFDOLPIGPR-UHFFFAOYSA-N 88485 N-(4-hydroxyphenyl)-4-[(5E)-5-[(3-methoxyphenyl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]butanamide::MLS001201619::N-(4-hydroxyphenyl)-4-[(5E)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]butanamide::N-(4-hydroxyphenyl)-4-[(5E)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanamide::cid_16440949::SMR000806117::N-(4-hydroxyphenyl)-4-[(5E)-4-keto-5-m-anisylidene-2-thioxo-thiazolidin-3-yl]butyramide Melanocortin receptor 4 Homo sapiens >89207 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88485&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16440949 252660199 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192640 CN(C)CCCN(C(=O)c1cc2cc(ccc2s1)[N+]([O-])=O)c1nc2cc3OCCOc3cc2s1 InChI=1S/C23H22N4O5S2/c1-25(2)6-3-7-26(22(28)21-11-14-10-15(27(29)30)4-5-19(14)33-21)23-24-16-12-17-18(13-20(16)34-23)32-9-8-31-17/h4-5,10-13H,3,6-9H2,1-2H3 JGWORRHJGYVGBZ-UHFFFAOYSA-N 66944 SMR000807865::cid_24892073::N-(6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)-N-[3-(dimethylamino)propyl]-5-nitro-1-benzothiophene-2-carboxamide;hydrochloride::MLS001239376::N-(6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)-N-[3-(dimethylamino)propyl]-5-nitro-benzothiophene-2-carboxamide;hydrochloride Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66944 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66944&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 24892074 252645256 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192641 Clc1ccc(C[n+]2c(cc(cc2-c2ccccc2)-c2ccccc2)-c2ccccc2)cc1 InChI=1S/C30H23ClN/c31-28-18-16-23(17-19-28)22-32-29(25-12-6-2-7-13-25)20-27(24-10-4-1-5-11-24)21-30(32)26-14-8-3-9-15-26/h1-21H,22H2/q+1 JNGBTISOFZDKDB-UHFFFAOYSA-N 88486 1-[(4-chlorophenyl)methyl]-2,4,6-triphenyl-pyridin-1-ium;perchlorate::SMR000841331::MLS001240926::cid_12402750::1-[(4-chlorophenyl)methyl]-2,4,6-triphenylpyridin-1-ium;perchlorate::1-(4-chlorobenzyl)-2,4,6-triphenyl-pyridin-1-ium;perchlorate Melanocortin receptor 4 Homo sapiens >89180 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88486&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3726853 252660200 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192642 COc1ccc2-c3onc(C(=O)Nc4ccn(Cc5ccc(C)cc5)n4)c3CCc2c1 InChI=1S/C24H22N4O3/c1-15-3-5-16(6-4-15)14-28-12-11-21(26-28)25-24(29)22-20-9-7-17-13-18(30-2)8-10-19(17)23(20)31-27-22/h3-6,8,10-13H,7,9,14H2,1-2H3,(H,25,26,29) XPHNVYPJDBMLSD-UHFFFAOYSA-N 37297 7-methoxy-N-[1-(4-methylbenzyl)-1H-pyrazol-3-yl]-4,5-dihydronaphtho[2,1-d]isoxazole-3-carboxamide::SMR000023680::7-methoxy-N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide::7-methoxy-N-[1-[(4-methylphenyl)methyl]pyrazol-3-yl]-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide::cid_3240939::MLS000087457::7-methoxy-N-[1-(4-methylbenzyl)pyrazol-3-yl]-4,5-dihydrobenz[g]indoxazene-3-carboxamide Melanocortin receptor 4 Homo sapiens >89169 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37297 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37297&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3240939 252618268 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192643 Clc1ccc(cc1)C1NC(=S)N=C2NC(N(C(=O)C12)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |t:12| InChI=1S/C24H17Cl3N4OS/c25-15-5-1-13(2-6-15)20-19-21(30-24(33)28-20)29-22(14-3-7-16(26)8-4-14)31(23(19)32)18-11-9-17(27)10-12-18/h1-12,19-20,22H,(H2,28,29,30,33) UYOLVCDCNXOLBF-UHFFFAOYSA-N 57212 SMR000155440::cid_5005059::4,6,7-tris(4-chlorophenyl)-2-sulfanylidene-3,4,7,8-tetrahydro-1H-pyrimido[4,5-d]pyrimidin-5-one::MLS000536083::4,6,7-tris(4-chlorophenyl)-2-thioxo-3,4,7,8-tetrahydro-1H-pyrimido[4,5-d]pyrimidin-5-one Melanocortin receptor 4 Homo sapiens 9627 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57212&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91897295 252637145 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192644 Cc1nnnn1\C(=C/c1ccccc1)C(=O)OCC(=O)Nc1ccc(Cl)cc1F InChI=1S/C19H15ClFN5O3/c1-12-23-24-25-26(12)17(9-13-5-3-2-4-6-13)19(28)29-11-18(27)22-16-8-7-14(20)10-15(16)21/h2-10H,11H2,1H3,(H,22,27) XOISWLLIPRDLDP-UHFFFAOYSA-N 88487 SMR000706997::MLS001080259::[2-(4-chloro-2-fluoroanilino)-2-oxoethyl] (Z)-2-(5-methyltetrazol-1-yl)-3-phenylprop-2-enoate::cid_18274125::[2-[(4-chloranyl-2-fluoranyl-phenyl)amino]-2-oxidanylidene-ethyl] (Z)-2-(5-methyl-1,2,3,4-tetrazol-1-yl)-3-phenyl-prop-2-enoate::(Z)-2-(5-methyl-1-tetrazolyl)-3-phenyl-2-propenoic acid [2-(4-chloro-2-fluoroanilino)-2-oxoethyl] ester::(Z)-2-(5-methyltetrazol-1-yl)-3-phenyl-acrylic acid [2-(4-chloro-2-fluoro-anilino)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >89220 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88487&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 18274125 252660201 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192645 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 InChI=1S/C27H42NO2/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23/h8-16H,17-22H2,1-7H3/q+1 SIYLLGKDQZGJHK-UHFFFAOYSA-N 50203812 cid_8478::CHEMBL221753::benzethonium hydrochloride Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203812 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203812&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 8478 104082770 CHEMBL221753 C08037 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192646 CCc1ccc(OCCNc2cc(ccc2[N+]([O-])=O)N2CCNC(C)C2)cc1 InChI=1S/C21H28N4O3/c1-3-17-4-7-19(8-5-17)28-13-11-23-20-14-18(6-9-21(20)25(26)27)24-12-10-22-16(2)15-24/h4-9,14,16,22-23H,3,10-13,15H2,1-2H3 DUCMTCXRNAFIQO-UHFFFAOYSA-N 79242 cid_5131252::N-[2-(4-ethylphenoxy)ethyl]-5-(3-methylpiperazin-1-yl)-2-nitro-aniline::N-[2-(4-ethylphenoxy)ethyl]-5-(3-methyl-1-piperazinyl)-2-nitroaniline::SMR001224417::MLS001359915::N-[2-(4-ethylphenoxy)ethyl]-5-(3-methylpiperazin-1-yl)-2-nitroaniline::2-(4-ethylphenoxy)ethyl-[5-(3-methylpiperazino)-2-nitro-phenyl]amine Melanocortin receptor 4 Homo sapiens >89196 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79242 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79242&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5131252 252655935 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192647 COc1ccc(cc1OC)-c1ccc2C(=O)c3c(cccc3S(=O)(=O)c2c1)C(=O)NCc1cc(C)oc1C(F)(F)F InChI=1S/C29H22F3NO7S/c1-15-11-18(27(40-15)29(30,31)32)14-33-28(35)20-5-4-6-23-25(20)26(34)19-9-7-17(13-24(19)41(23,36)37)16-8-10-21(38-2)22(12-16)39-3/h4-13H,14H2,1-3H3,(H,33,35) NYKRTEXSTJEQLZ-UHFFFAOYSA-N 88488 MLS001144825::6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)furan-3-yl]methyl]-9,10,10-trioxothioxanthene-1-carboxamide::6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)furan-3-yl]methyl]-9,10,10-tris(oxidanylidene)thioxanthene-1-carboxamide::cid_44141945::SMR000568214::6-(3,4-dimethoxyphenyl)-N-[[5-methyl-2-(trifluoromethyl)-3-furanyl]methyl]-9,10,10-trioxo-1-thioxanthenecarboxamide::6-(3,4-dimethoxyphenyl)-9,10,10-triketo-N-[[5-methyl-2-(trifluoromethyl)-3-furyl]methyl]thioxanthene-1-carboxamide Melanocortin receptor 4 Homo sapiens >89186 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88488&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44141945 252660202 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192648 COc1cc(OC)cc(\C=C2/Oc3ccc(cc3C2=O)C#Cc2ccc(O)cc2)c1 InChI=1S/C25H18O5/c1-28-20-11-18(12-21(15-20)29-2)14-24-25(27)22-13-17(7-10-23(22)30-24)4-3-16-5-8-19(26)9-6-16/h5-15,26H,1-2H3 KBJSXLBQQHWEOV-UHFFFAOYSA-N 88489 cid_44202176::(2Z)-2-[(3,5-dimethoxyphenyl)methylidene]-5-[2-(4-hydroxyphenyl)ethynyl]-3-benzofuranone::(2Z)-2-[(3,5-dimethoxyphenyl)methylidene]-5-[2-(4-hydroxyphenyl)ethynyl]-1-benzofuran-3-one::MLS002473510::SMR001397678::(2Z)-2-(3,5-dimethoxybenzylidene)-5-[2-(4-hydroxyphenyl)ethynyl]coumaran-3-one Melanocortin receptor 4 Homo sapiens >89213 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88489&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202176 252660203 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192649 COc1ccc(cc1)-c1sc2ccc(cc2c1C#CC1(O)CCCCC1)N1CCOCC1 InChI=1S/C27H29NO3S/c1-30-22-8-5-20(6-9-22)26-23(11-14-27(29)12-3-2-4-13-27)24-19-21(7-10-25(24)32-26)28-15-17-31-18-16-28/h5-10,19,29H,2-4,12-13,15-18H2,1H3 SNIBQJOOPDMVHF-UHFFFAOYSA-N 88490 MLS002473545::SMR001397713::1-[2-[2-(4-methoxyphenyl)-5-morpholin-4-yl-1-benzothiophen-3-yl]ethynyl]cyclohexan-1-ol::cid_44202203::1-[2-[2-(4-methoxyphenyl)-5-(4-morpholinyl)-1-benzothiophen-3-yl]ethynyl]-1-cyclohexanol::1-[2-[2-(4-methoxyphenyl)-5-morpholino-benzothiophen-3-yl]ethynyl]cyclohexanol Melanocortin receptor 4 Homo sapiens >89180 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88490&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202203 252660204 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192650 COc1ccc2sc(c(C#Cc3cncn3C)c2c1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H18N2O3S2/c1-24-14-23-13-16(24)6-10-19-20-12-17(27-2)7-11-21(20)28-22(19)15-4-8-18(9-5-15)29(3,25)26/h4-5,7-9,11-14H,1-3H3 AAHMFTBCVJDHBJ-UHFFFAOYSA-N 88491 SMR001397736::5-[2-[5-methoxy-2-(4-methylsulfonylphenyl)-1-benzothiophen-3-yl]ethynyl]-1-methylimidazole::MLS002473569::5-[2-[5-methoxy-2-(4-methylsulfonylphenyl)-1-benzothiophen-3-yl]ethynyl]-1-methyl-imidazole::cid_44202221::5-[2-[2-(4-mesylphenyl)-5-methoxy-benzothiophen-3-yl]ethynyl]-1-methyl-imidazole Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88491 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88491&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202221 252660205 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192651 CN(C)CCOc1ccc(cc1)-c1c(sc2ccccc12)-c1ccsc1 InChI=1S/C22H21NOS2/c1-23(2)12-13-24-18-9-7-16(8-10-18)21-19-5-3-4-6-20(19)26-22(21)17-11-14-25-15-17/h3-11,14-15H,12-13H2,1-2H3 RLHRDPKMXPSPON-UHFFFAOYSA-N 79374 cid_44202260::N,N-dimethyl-2-[4-[2-(3-thiophenyl)-1-benzothiophen-3-yl]phenoxy]ethanamine::MLS002473616::N,N-dimethyl-2-[4-(2-thiophen-3-yl-1-benzothiophen-3-yl)phenoxy]ethanamine::SMR001397783::dimethyl-[2-[4-[2-(3-thienyl)benzothiophen-3-yl]phenoxy]ethyl]amine Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79374 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79374&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202260 252656033 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192652 C(CN1CCCC1)Oc1ccc(cc1)-c1c(sc2ccccc12)-c1ccccc1 InChI=1S/C26H25NOS/c1-2-8-21(9-3-1)26-25(23-10-4-5-11-24(23)29-26)20-12-14-22(15-13-20)28-19-18-27-16-6-7-17-27/h1-5,8-15H,6-7,16-19H2 ZLJCFEHKTHXYOP-UHFFFAOYSA-N 67060 1-[2-[4-(2-phenyl-1-benzothiophen-3-yl)phenoxy]ethyl]pyrrolidine::MLS002473624::cid_44202267::SMR001397791::1-[2-[4-(2-phenylbenzothiophen-3-yl)phenoxy]ethyl]pyrrolidine Melanocortin receptor 4 Homo sapiens >89179 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67060 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67060&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202267 252645367 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192653 CN(C)CCOc1ccc(cc1)-c1c(sc2ccccc12)-c1ccccc1 InChI=1S/C24H23NOS/c1-25(2)16-17-26-20-14-12-18(13-15-20)23-21-10-6-7-11-22(21)27-24(23)19-8-4-3-5-9-19/h3-15H,16-17H2,1-2H3 HQDXGLXETMQWFK-UHFFFAOYSA-N 75439 SMR001397792::MLS002473625::N,N-dimethyl-2-[4-(2-phenyl-1-benzothiophen-3-yl)phenoxy]ethanamine::cid_44202268::dimethyl-[2-[4-(2-phenylbenzothiophen-3-yl)phenoxy]ethyl]amine Melanocortin receptor 4 Homo sapiens >89191 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75439 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75439&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202268 252652648 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192654 COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN(C)C)cc1 InChI=1S/C25H25NO2S/c1-26(2)15-16-28-20-13-11-18(12-14-20)24-22-9-4-5-10-23(22)29-25(24)19-7-6-8-21(17-19)27-3/h4-14,17H,15-16H2,1-3H3 GLBKTSMZCIBQGM-UHFFFAOYSA-N 75442 cid_44202272::SMR001397796::MLS002473629::2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]phenoxy]-N,N-dimethylethanamine::2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]phenoxy]-N,N-dimethyl-ethanamine::2-[4-[2-(3-methoxyphenyl)benzothiophen-3-yl]phenoxy]ethyl-dimethyl-amine::22GW (17b) Melanocortin receptor 4 Homo sapiens >3304 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75442 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75442&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202272 252652651 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192655 COc1ccc(cc1)-c1sc2ccccc2c1-c1ccc(OCCN(C)C)cc1 InChI=1S/C25H25NO2S/c1-26(2)16-17-28-21-14-8-18(9-15-21)24-22-6-4-5-7-23(22)29-25(24)19-10-12-20(27-3)13-11-19/h4-15H,16-17H2,1-3H3 IHDTVQWTNDELLP-UHFFFAOYSA-N 75443 MLS002473632::cid_44202275::SMR001397799::2-[4-[2-(4-methoxyphenyl)-1-benzothiophen-3-yl]phenoxy]-N,N-dimethyl-ethanamine::2-[4-[2-(4-methoxyphenyl)-1-benzothiophen-3-yl]phenoxy]-N,N-dimethylethanamine::2-[4-[2-(4-methoxyphenyl)benzothiophen-3-yl]phenoxy]ethyl-dimethyl-amine::234J (17k) Melanocortin receptor 4 Homo sapiens >89213 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75443 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75443&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44202275 252652652 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192656 CCN1C(=O)\C(S\C1=N/c1cccc(O)c1)=C1\Sc2ccc(OC)cc2N1C InChI=1S/C20H19N3O3S2/c1-4-23-18(25)17(28-20(23)21-12-6-5-7-13(24)10-12)19-22(2)15-11-14(26-3)8-9-16(15)27-19/h5-11,24H,4H2,1-3H3 PIUUJWICZDNLGV-UHFFFAOYSA-N 38864 MLS000070302::cid_1718638::(5Z)-3-ethyl-2-(3-hydroxyphenyl)imino-5-(5-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)-1,3-thiazolidin-4-one::(5Z)-3-ethyl-2-(3-hydroxyphenyl)imino-5-(5-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)-4-thiazolidinone::3-Ethyl-2-[(Z)-3-hydroxy-phenylimino]-5-[5-methoxy-3-methyl-3H-benzothiazol-(2Z)-ylidene]-thiazolidin-4-one::SMR000008533::(5Z)-3-ethyl-2-(3-hydroxyphenyl)imino-5-(5-methoxy-3-methyl-1,3-benzothiazol-2-ylidene)thiazolidin-4-one Melanocortin receptor 4 Homo sapiens >89207 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38864 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38864&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1718638 252619767 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192657 CCn1c(SCC(=O)Nc2ccc(cc2)C(C)=O)nc2nc3CCCCc3cc2c1=O InChI=1S/C23H24N4O3S/c1-3-27-22(30)18-12-16-6-4-5-7-19(16)25-21(18)26-23(27)31-13-20(29)24-17-10-8-15(9-11-17)14(2)28/h8-12H,3-7,13H2,1-2H3,(H,24,29) PNRHTNSMLZUVQQ-UHFFFAOYSA-N 48700 N-(4-acetylphenyl)-2-[(3-ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]acetamide::SMR000200701::cid_1996177::N-(4-acetylphenyl)-2-[(3-ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)thio]acetamide::MLS000582167::N-(4-ethanoylphenyl)-2-[(3-ethyl-4-oxidanylidene-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]ethanamide::N-(4-acetylphenyl)-2-[(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[4,5-b]quinolin-2-yl)thio]acetamide::N-(4-acetylphenyl)-2-[(3-ethyl-4-keto-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)thio]acetamide Melanocortin receptor 4 Homo sapiens >89213 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48700 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48700&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1996177 252628987 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192658 CCCCCCCCCCCCCCCC[n+]1cccc(c1)C(=O)N(CC)CC InChI=1S/C26H47N2O/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-22-27-23-20-21-25(24-27)26(29)28(5-2)6-3/h20-21,23-24H,4-19,22H2,1-3H3/q+1 HPBFEAUPKBNRCI-UHFFFAOYSA-N 48733 1-cetyl-N,N-diethyl-pyridin-1-ium-3-carboxamide;chloride::MLS000587364::N,N-diethyl-1-hexadecyl-3-pyridin-1-iumcarboxamide;bromide::N,N-diethyl-1-hexadecylpyridin-1-ium-3-carboxamide;bromide::3-Diethylcarbamoyl-1-hexadecyl-pyridinium::SMR000211414::cid_12005597::N,N-diethyl-1-hexadecyl-pyridin-1-ium-3-carboxamide;bromide::1-cetyl-N,N-diethyl-pyridin-1-ium-3-carboxamide;bromide Melanocortin receptor 4 Homo sapiens >89228 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48733 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48733&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4324080 252629020 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192659 Oc1ccc(Br)cc1C1(OC(=O)c2ccccc12)c1ccccc1 InChI=1S/C20H13BrO3/c21-14-10-11-18(22)17(12-14)20(13-6-2-1-3-7-13)16-9-5-4-8-15(16)19(23)24-20/h1-12,22H WPSPHXZZWGJJQK-UHFFFAOYSA-N 88493 cid_228252::SMR001548228::3-(5-bromo-2-hydroxyphenyl)-3-phenyl-2-benzofuran-1-one::MLS002638762::3-(5-bromo-2-hydroxyphenyl)-3-phenyl-1-isobenzofuranone::3-(5-bromanyl-2-oxidanyl-phenyl)-3-phenyl-2-benzofuran-1-one::3-(5-bromo-2-hydroxy-phenyl)-3-phenyl-phthalide Melanocortin receptor 4 Homo sapiens >89229 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88493&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 228252 252660206 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192660 Oc1ccc(cc1)C1(OC(=O)c2ccccc12)c1ccccc1 InChI=1S/C20H14O3/c21-16-12-10-15(11-13-16)20(14-6-2-1-3-7-14)18-9-5-4-8-17(18)19(22)23-20/h1-13,21H NHXWHNLPLPWQIG-UHFFFAOYSA-N 88494 3-(4-hydroxyphenyl)-3-phenyl-1-isobenzofuranone::cid_228383::3-(4-hydroxyphenyl)-3-phenyl-2-benzofuran-1-one::SMR001548244::MLS002638779::3-(4-hydroxyphenyl)-3-phenyl-phthalide Melanocortin receptor 4 Homo sapiens >89218 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88494 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88494&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 228383 252660207 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192661 Cc1cc(C)c(CN2CCN(CCCn3cnc(n3)C(=O)Nc3ccc(C)c(C)c3)CC2)c(C)c1 InChI=1S/C28H38N6O/c1-20-15-23(4)26(24(5)16-20)18-33-13-11-32(12-14-33)9-6-10-34-19-29-27(31-34)28(35)30-25-8-7-21(2)22(3)17-25/h7-8,15-17,19H,6,9-14,18H2,1-5H3,(H,30,35) SQJMDULSKKWATL-UHFFFAOYSA-N 88495 SMR001595293::MLS002724427::N-(3,4-dimethylphenyl)-1-[3-[4-[(2,4,6-trimethylphenyl)methyl]piperazin-1-yl]propyl]-1,2,4-triazole-3-carboxamide::cid_45281081::N-(3,4-dimethylphenyl)-1-[3-[4-[(2,4,6-trimethylphenyl)methyl]-1-piperazinyl]propyl]-1,2,4-triazole-3-carboxamide::N-(3,4-dimethylphenyl)-1-[3-[4-(2,4,6-trimethylbenzyl)piperazino]propyl]-1,2,4-triazole-3-carboxamide Melanocortin receptor 4 Homo sapiens >89180 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88495&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 45281081 252660208 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192662 Cc1ccc(NC(=O)c2ncn(CCCN3CCN(Cc4cccc5ccccc45)CC3)n2)cc1C InChI=1S/C29H34N6O/c1-22-11-12-26(19-23(22)2)31-29(36)28-30-21-35(32-28)14-6-13-33-15-17-34(18-16-33)20-25-9-5-8-24-7-3-4-10-27(24)25/h3-5,7-12,19,21H,6,13-18,20H2,1-2H3,(H,31,36) PBIRWBYBLVJYFN-UHFFFAOYSA-N 88496 N-(3,4-dimethylphenyl)-1-[3-[4-(naphthalen-1-ylmethyl)piperazin-1-yl]propyl]-1,2,4-triazole-3-carboxamide::MLS002724443::cid_45281097::SMR001595309::N-(3,4-dimethylphenyl)-1-[3-[4-(1-naphthalenylmethyl)-1-piperazinyl]propyl]-1,2,4-triazole-3-carboxamide::N-(3,4-dimethylphenyl)-1-[3-[4-(1-naphthylmethyl)piperazino]propyl]-1,2,4-triazole-3-carboxamide Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88496 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88496&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 45281097 252660209 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192663 CCN1CCC(O)(\C=C\c2ccc(cc2)C(C)C)C(C1)C(=O)C=Cc1ccc(cc1)C(C)C |w:22.23| InChI=1S/C30H39NO2/c1-6-31-20-19-30(33,18-17-25-9-14-27(15-10-25)23(4)5)28(21-31)29(32)16-11-24-7-12-26(13-8-24)22(2)3/h7-18,22-23,28,33H,6,19-21H2,1-5H3 WZLWYHADODLHEK-UHFFFAOYSA-N 88497 cid_5469647::MLS002702405::(E)-1-[1-ethyl-4-oxidanyl-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]piperidin-3-yl]-3-(4-propan-2-ylphenyl)prop-2-en-1-one;hydrochloride::(E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]piperidin-3-yl]-3-(4-propan-2-ylphenyl)prop-2-en-1-one;hydrochloride::SMR001565967::(E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]-3-piperidinyl]-3-(4-propan-2-ylphenyl)-2-propen-1-one;hydrochloride::(E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-p-cumenylvinyl]-3-piperidyl]-3-p-cumenyl-prop-2-en-1-one;hydrochloride Melanocortin receptor 4 Homo sapiens >89159 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88497&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5469648 252660210 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192664 CCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccc(F)cc1 InChI=1S/C25H45FN/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-27(2,3)23-24-18-20-25(26)21-19-24/h18-21H,4-17,22-23H2,1-3H3/q+1 IGFHCKWGBWALHX-UHFFFAOYSA-N 88498 MLS002702413::cid_392616::(4-fluorophenyl)methyl-hexadecyl-dimethylammonium;chloride::(4-fluorophenyl)methyl-hexadecyl-dimethyl-azanium;chloride::(4-fluorophenyl)methyl-hexadecyl-dimethylazanium;chloride::SMR001565975::cetyl-(4-fluorobenzyl)-dimethyl-ammonium;chloride Melanocortin receptor 4 Homo sapiens >89187 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88498&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 392617 252660211 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192665 CCCCCCCCNS(=O)(=O)CCNCCc1ccccc1 InChI=1S/C18H32N2O2S/c1-2-3-4-5-6-10-14-20-23(21,22)17-16-19-15-13-18-11-8-7-9-12-18/h7-9,11-12,19-20H,2-6,10,13-17H2,1H3 MKSFRRMPGFANFG-UHFFFAOYSA-N 88499 MLS002768255::KUC104001::cid_45479968::SMR001788221::N-octyl-2-(2-phenylethylamino)ethanesulfonamide::N-octyl-2-(phenethylamino)ethanesulfonamide Melanocortin receptor 4 Homo sapiens >89128 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88499&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 45479968 252660212 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192666 CC(O)CC(=O)OC[C@]12CC[C@H]3[C@@](C)(CC[C@H]4C(C)(C)CCC[C@]34C)[C@@H]1CC(O2)C1=CC(=O)OC1O |t:33| InChI=1S/C29H44O7/c1-17(30)13-23(31)34-16-29-12-8-21-27(4)10-6-9-26(2,3)20(27)7-11-28(21,5)22(29)15-19(36-29)18-14-24(32)35-25(18)33/h14,17,19-22,25,30,33H,6-13,15-16H2,1-5H3 CNOLKJVBUJUUQA-UHFFFAOYSA-N 88500 MLS001250237::3-hydroxybutanoic acid [(3aS,3bR,5aS,9aS,9bR,11aS)-2-(2-hydroxy-5-oxo-2H-furan-3-yl)-3b,6,6,9a-tetramethyl-2,3,3a,4,5,5a,7,8,9,9b,10,11-dodecahydronaphtho[2,1-e]benzofuran-11a-yl]methyl ester::cid_46902089::[(3aS,3bR,5aS,9aS,9bR,11aS)-3b,6,6,9a-tetramethyl-2-(2-oxidanyl-5-oxidanylidene-2H-furan-3-yl)-2,3,3a,4,5,5a,7,8,9,9b,10,11-dodecahydronaphtho[2,1-e][1]benzofuran-11a-yl]methyl 3-oxidanylbutanoate::SMR001216067::[(3aS,3bR,5aS,9aS,9bR,11aS)-2-(2-hydroxy-5-oxo-2H-furan-3-yl)-3b,6,6,9a-tetramethyl-2,3,3a,4,5,5a,7,8,9,9b,10,11-dodecahydronaphtho[2,1-e][1]benzofuran-11a-yl]methyl 3-hydroxybutanoate::3-hydroxybutyric acid [(3aS,3bR,5aS,9aS,9bR,11aS)-2-(2-hydroxy-5-keto-2H-furan-3-yl)-3b,6,6,9a-tetramethyl-2,3,3a,4,5,5a,7,8,9,9b,10,11-dodecahydronaphtho[2,1-e]benzofuran-11a-yl]methyl ester Melanocortin receptor 4 Homo sapiens >89200 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88500 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88500&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46902089 252660213 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192667 CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)C(=O)c4c[nH]c5ccccc45)c3)cc2C(F)(F)F)CC1 InChI=1S/C32H32F3N5O3/c1-3-39-12-14-40(15-13-39)19-22-10-11-23(17-26(22)32(33,34)35)37-30(42)21-9-8-20(2)28(16-21)38-31(43)29(41)25-18-36-27-7-5-4-6-24(25)27/h4-11,16-18,36H,3,12-15,19H2,1-2H3,(H,37,42)(H,38,43) BQRFGIIHXOVNDN-UHFFFAOYSA-N 51933 N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-4-methyl-benzamide::SMR000718306::MLS000911609::N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxoacetyl]amino]-4-methylbenzamide;2,2,2-trifluoroacetic acid::N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-1,2-dioxoethyl]amino]-4-methylbenzamide;2,2,2-trifluoroacetic acid::cid_24816489::N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxidanylidene-ethanoyl]amino]-4-methyl-benzamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-4-methyl-benzamide;2,2,2-trifluoroacetic acid Melanocortin receptor 4 Homo sapiens >89190 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51933 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51933&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16745799 252632090 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192668 CCN1CCN(Cc2ccc(NC(=O)c3cc(NC(=O)C(=O)c4c[nH]c5ccccc45)cc(OC)c3)cc2C(F)(F)F)CC1 InChI=1S/C32H32F3N5O4/c1-3-39-10-12-40(13-11-39)19-20-8-9-22(17-27(20)32(33,34)35)37-30(42)21-14-23(16-24(15-21)44-2)38-31(43)29(41)26-18-36-28-7-5-4-6-25(26)28/h4-9,14-18,36H,3,10-13,19H2,1-2H3,(H,37,42)(H,38,43) OOZMZKSKADJYMS-UHFFFAOYSA-N 51890 N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxoacetyl]amino]-5-methoxybenzamide::N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-oxidanylidene-ethanoyl]amino]-5-methoxy-benzamide::MLS000911514::N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-5-methoxy-benzamide;2,2,2-trifluoroacetic acid::cid_16745813::N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-1,2-dioxoethyl]amino]-5-methoxybenzamide::SMR000453564::N-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[[2-(1H-indol-3-yl)-2-keto-acetyl]amino]-5-methoxy-benzamide Melanocortin receptor 4 Homo sapiens >89182 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51890 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51890&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16745813 252632049 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192669 CCN1CCN(Cc2ccc(NC(=O)c3cc(NC(=O)c4cc5cccc(OC)c5o4)cc(OC)c3)cc2C(F)(F)F)CC1 InChI=1S/C32H33F3N4O5/c1-4-38-10-12-39(13-11-38)19-21-8-9-23(18-26(21)32(33,34)35)36-30(40)22-14-24(17-25(15-22)42-2)37-31(41)28-16-20-6-5-7-27(43-3)29(20)44-28/h5-9,14-18H,4,10-13,19H2,1-3H3,(H,36,40)(H,37,41) JDJYWNRPLBNDBK-UHFFFAOYSA-N 55931 SMR000463588::cid_16746137::N-[3-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxyphenyl]-7-methoxy-1-benzofuran-2-carboxamide::MLS000911573::N-[3-[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)anilino]-oxomethyl]-5-methoxyphenyl]-7-methoxy-2-benzofurancarboxamide::N-[3-[[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]-7-methoxy-coumarilamide;2,2,2-trifluoroacetic acid::N-[3-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]-7-methoxy-1-benzofuran-2-carboxamide::N-[3-[[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]-7-methoxy-coumarilamide Melanocortin receptor 4 Homo sapiens >89208 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55931 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55931&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16746137 252635910 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192670 CCN1CCN(Cc2ccc(NC(=O)c3cc(NC(=O)c4cncc(c4)-c4ccc(cc4)C#N)cc(OC)c3)cc2C(F)(F)F)CC1 InChI=1S/C35H33F3N6O3/c1-3-43-10-12-44(13-11-43)22-25-8-9-29(18-32(25)35(36,37)38)41-33(45)26-15-30(17-31(16-26)47-2)42-34(46)28-14-27(20-40-21-28)24-6-4-23(19-39)5-7-24/h4-9,14-18,20-21H,3,10-13,22H2,1-2H3,(H,41,45)(H,42,46) FXTAYCDVJNAKHY-UHFFFAOYSA-N 55930 5-(4-cyanophenyl)-N-[3-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxyphenyl]pyridine-3-carboxamide::5-(4-cyanophenyl)-N-[3-[[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]nicotinamide;2,2,2-trifluoroacetic acid::cid_16746136::5-(4-cyanophenyl)-N-[3-[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)anilino]-oxomethyl]-5-methoxyphenyl]-3-pyridinecarboxamide::5-(4-cyanophenyl)-N-[3-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]pyridine-3-carboxamide::MLS000911575::SMR000463590::5-(4-cyanophenyl)-N-[3-[[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-5-methoxy-phenyl]nicotinamide Melanocortin receptor 4 Homo sapiens >89212 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55930 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55930&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16746136 252635909 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192671 COc1ccc(cn1)C(NC(=O)C1CCN(CCOc2ccc(Cl)cc2Cl)CC1)c1ccccc1C InChI=1S/C28H31Cl2N3O3/c1-19-5-3-4-6-23(19)27(21-7-10-26(35-2)31-18-21)32-28(34)20-11-13-33(14-12-20)15-16-36-25-9-8-22(29)17-24(25)30/h3-10,17-18,20,27H,11-16H2,1-2H3,(H,32,34) JEUHINYNAOUGIF-UHFFFAOYSA-N 88504 MLS003121753::1-[2-[2,4-bis(chloranyl)phenoxy]ethyl]-N-[(6-methoxypyridin-3-yl)-(2-methylphenyl)methyl]piperidine-4-carboxamide::cid_46942448::1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxypyridin-3-yl)-(2-methylphenyl)methyl]piperidine-4-carboxamide::1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxy-3-pyridinyl)-(2-methylphenyl)methyl]-4-piperidinecarboxamide::SMR001284950::1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(6-methoxy-3-pyridyl)-(o-tolyl)methyl]isonipecotamide Melanocortin receptor 4 Homo sapiens >89207 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88504&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942448 252660214 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192672 NC(c1csc(NC(=O)Nc2ccccc2Oc2ccccc2)n1)c1ccccc1 InChI=1S/C23H20N4O2S/c24-21(16-9-3-1-4-10-16)19-15-30-23(26-19)27-22(28)25-18-13-7-8-14-20(18)29-17-11-5-2-6-12-17/h1-15,21H,24H2,(H2,25,26,27,28) BHAANUCEUMXLIS-UHFFFAOYSA-N 88505 cid_46942493::1-[4-[azanyl(phenyl)methyl]-1,3-thiazol-2-yl]-3-(2-phenoxyphenyl)urea::SMR001292121::1-[4-[amino(phenyl)methyl]-1,3-thiazol-2-yl]-3-(2-phenoxyphenyl)urea::1-[4-[amino(phenyl)methyl]-2-thiazolyl]-3-(2-phenoxyphenyl)urea::MLS003123949::1-[4-[amino(phenyl)methyl]thiazol-2-yl]-3-(2-phenoxyphenyl)urea Melanocortin receptor 4 Homo sapiens >89233 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88505 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88505&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942493 252660215 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192673 CC(=O)Nc1cc(cn2c(cnc12)-c1cccc(c1)C(F)(F)F)-c1cccnc1 InChI=1S/C21H15F3N4O/c1-13(29)27-18-9-16(15-5-3-7-25-10-15)12-28-19(11-26-20(18)28)14-4-2-6-17(8-14)21(22,23)24/h2-12H,1H3,(H,27,29) FPCKADRBYIWIBN-UHFFFAOYSA-N 88506 SMR001292797::MLS003124262::N-[6-pyridin-3-yl-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]acetamide::N-[6-pyridin-3-yl-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]ethanamide::cid_46942512::N-[6-(3-pyridinyl)-3-[3-(trifluoromethyl)phenyl]-8-imidazo[1,2-a]pyridinyl]acetamide::N-[6-(3-pyridyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens 84105 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88506 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88506&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942512 252660216 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192674 CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)c(Cl)c1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H17ClFN3O3S/c1-13(28)26-20-10-16(14-3-6-17(7-4-14)31(2,29)30)12-27-21(11-25-22(20)27)15-5-8-19(24)18(23)9-15/h3-12H,1-2H3,(H,26,28) SEMSAWPZVOVTCG-UHFFFAOYSA-N 88507 N-[3-(3-chloro-4-fluorophenyl)-6-(4-methylsulfonylphenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::MLS003124175::cid_46942664::N-[3-(3-chloranyl-4-fluoranyl-phenyl)-6-(4-methylsulfonylphenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[3-(3-chloro-4-fluorophenyl)-6-(4-methylsulfonylphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide::SMR001292665::N-[3-(3-chloro-4-fluoro-phenyl)-6-(4-mesylphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89191 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88507&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942664 252660217 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192675 COc1ccccc1NC(=O)Nc1nc(cs1)C(N)Cc1ccc(Cl)cc1 InChI=1S/C19H19ClN4O2S/c1-26-17-5-3-2-4-15(17)22-18(25)24-19-23-16(11-27-19)14(21)10-12-6-8-13(20)9-7-12/h2-9,11,14H,10,21H2,1H3,(H2,22,23,24,25) FCRFNXVOUOIFQR-UHFFFAOYSA-N 88508 1-[4-[1-azanyl-2-(4-chlorophenyl)ethyl]-1,3-thiazol-2-yl]-3-(2-methoxyphenyl)urea::1-[4-[1-amino-2-(4-chlorophenyl)ethyl]-1,3-thiazol-2-yl]-3-(2-methoxyphenyl)urea::SMR001292144::1-[4-[1-amino-2-(4-chlorophenyl)ethyl]-2-thiazolyl]-3-(2-methoxyphenyl)urea::MLS003123955::cid_46942726::1-[4-[1-amino-2-(4-chlorophenyl)ethyl]thiazol-2-yl]-3-(2-methoxyphenyl)urea Melanocortin receptor 4 Homo sapiens >89197 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88508&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942726 252660218 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192676 COc1cccc(c1)-c1cnc2c(NC=O)cc(cn12)-c1cc(OC)c(OC)c(OC)c1 InChI=1S/C24H23N3O5/c1-29-18-7-5-6-15(8-18)20-12-25-24-19(26-14-28)9-17(13-27(20)24)16-10-21(30-2)23(32-4)22(11-16)31-3/h5-14H,1-4H3,(H,26,28) XJGNVVOGXAZJNB-UHFFFAOYSA-N 88509 MLS003124139::N-[3-(3-methoxyphenyl)-6-(3,4,5-trimethoxyphenyl)-8-imidazo[1,2-a]pyridinyl]formamide::SMR001292602::cid_46942899::N-[3-(3-methoxyphenyl)-6-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyridin-8-yl]methanamide::N-[3-(3-methoxyphenyl)-6-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyridin-8-yl]formamide Melanocortin receptor 4 Homo sapiens >89235 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88509&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46942899 252660219 C06049 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192677 CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)cc1)-c1cccnc1 InChI=1S/C20H15FN4O/c1-13(26)24-18-9-16(15-3-2-8-22-10-15)12-25-19(11-23-20(18)25)14-4-6-17(21)7-5-14/h2-12H,1H3,(H,24,26) VUTMXPKKLWRPIA-UHFFFAOYSA-N 88510 N-[3-(4-fluorophenyl)-6-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]acetamide::MLS003124196::N-[3-(4-fluorophenyl)-6-pyridin-3-yl-imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[3-(4-fluorophenyl)-6-(3-pyridinyl)-8-imidazo[1,2-a]pyridinyl]acetamide::SMR001292695::cid_46943089::N-[3-(4-fluorophenyl)-6-(3-pyridyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89170 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88510 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88510&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943089 252660220 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192678 COc1ccc(cc1OC)-c1cnc2c(NC(C)=O)cc(cn12)-c1cc(F)ccc1OC InChI=1S/C24H22FN3O4/c1-14(29)27-19-9-16(18-11-17(25)6-8-21(18)30-2)13-28-20(12-26-24(19)28)15-5-7-22(31-3)23(10-15)32-4/h5-13H,1-4H3,(H,27,29) YJZQESKOKSOFQC-UHFFFAOYSA-N 88511 N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxyphenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoranyl-2-methoxy-phenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::SMR001292721::N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide::cid_46943096::MLS003124211::N-[3-(3,4-dimethoxyphenyl)-6-(5-fluoro-2-methoxy-phenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89214 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88511 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88511&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943096 252660221 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192679 CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)cc1)-c1cccc(F)c1 InChI=1S/C21H15F2N3O/c1-13(27)25-19-10-16(15-3-2-4-18(23)9-15)12-26-20(11-24-21(19)26)14-5-7-17(22)8-6-14/h2-12H,1H3,(H,25,27) DCLGIQNIXSIEPG-UHFFFAOYSA-N 88512 cid_46943131::SMR001292701::N-[6-(3-fluorophenyl)-3-(4-fluorophenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::MLS003124320::N-[6-(3-fluorophenyl)-3-(4-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[6-(3-fluorophenyl)-3-(4-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89198 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88512 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88512&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943131 252660222 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192680 COc1ccc(cc1OC)-c1cnc2c(NC(C)=O)cc(cn12)-c1ccc(OC)c(OC)c1 InChI=1S/C25H25N3O5/c1-15(29)27-19-10-18(16-6-8-21(30-2)23(11-16)32-4)14-28-20(13-26-25(19)28)17-7-9-22(31-3)24(12-17)33-5/h6-14H,1-5H3,(H,27,29) UFBKHSQSNDHQQX-UHFFFAOYSA-N 88513 MLS003124204::SMR001292710::cid_46943460::N-[3,6-bis(3,4-dimethoxyphenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::N-[3,6-bis(3,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[3,6-bis(3,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89224 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88513 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88513&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943460 252660223 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192681 COc1ccc(c(OC)c1)-c1cc(NC(C)=O)c2ncc(-c3cccc(c3)C(F)(F)F)n2c1 InChI=1S/C24H20F3N3O3/c1-14(31)29-20-10-16(19-8-7-18(32-2)11-22(19)33-3)13-30-21(12-28-23(20)30)15-5-4-6-17(9-15)24(25,26)27/h4-13H,1-3H3,(H,29,31) LJKIFWXNVXNECL-UHFFFAOYSA-N 88514 SMR001292794::N-[6-(2,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]-8-imidazo[1,2-a]pyridinyl]acetamide::cid_46943491::N-[6-(2,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]ethanamide::MLS003124257::N-[6-(2,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89185 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88514&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943491 252660224 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192682 COc1ccc(CNC(=O)Nc2nc(cs2)C(N)Cc2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C21H21F3N4O2S/c1-30-16-8-4-14(5-9-16)11-26-19(29)28-20-27-18(12-31-20)17(25)10-13-2-6-15(7-3-13)21(22,23)24/h2-9,12,17H,10-11,25H2,1H3,(H2,26,27,28,29) YEZZUHWXEQCZLW-UHFFFAOYSA-N 88515 1-[4-[1-azanyl-2-[4-(trifluoromethyl)phenyl]ethyl]-1,3-thiazol-2-yl]-3-[(4-methoxyphenyl)methyl]urea::cid_46943685::MLS003123952::SMR001292125::1-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-1,3-thiazol-2-yl]-3-[(4-methoxyphenyl)methyl]urea::1-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-2-thiazolyl]-3-[(4-methoxyphenyl)methyl]urea::1-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]thiazol-2-yl]-3-p-anisyl-urea Melanocortin receptor 4 Homo sapiens >89191 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88515 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88515&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943685 252660225 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192683 CN(C(c1ccc(F)cc1)c1ncccc1C)C(=O)C1CCN(CCOc2ccc(Cl)cc2Cl)CC1 InChI=1S/C28H30Cl2FN3O2/c1-19-4-3-13-32-26(19)27(20-5-8-23(31)9-6-20)33(2)28(35)21-11-14-34(15-12-21)16-17-36-25-10-7-22(29)18-24(25)30/h3-10,13,18,21,27H,11-12,14-17H2,1-2H3 WFTORSOXVDSRQK-UHFFFAOYSA-N 88516 1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methylpyridin-2-yl)methyl]-N-methylpiperidine-4-carboxamide::MLS003121715::SMR001284801::cid_46943740::1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methyl-2-pyridinyl)methyl]-N-methyl-4-piperidinecarboxamide::1-[2-[2,4-bis(chloranyl)phenoxy]ethyl]-N-[(4-fluorophenyl)-(3-methylpyridin-2-yl)methyl]-N-methyl-piperidine-4-carboxamide::1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methyl-2-pyridyl)methyl]-N-methyl-isonipecotamide Melanocortin receptor 4 Homo sapiens >89222 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88516 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88516&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943740 252660226 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192684 CN(C)c1ccc(cc1)-c1cc(NC=O)c2ncc(-c3cccc(c3)C(C)=O)n2c1 InChI=1S/C24H22N4O2/c1-16(30)18-5-4-6-19(11-18)23-13-25-24-22(26-15-29)12-20(14-28(23)24)17-7-9-21(10-8-17)27(2)3/h4-15H,1-3H3,(H,26,29) OZGQNKAPFKHVKJ-UHFFFAOYSA-N 88517 SMR001292564::N-[6-[4-(dimethylamino)phenyl]-3-(3-ethanoylphenyl)imidazo[1,2-a]pyridin-8-yl]methanamide::cid_46943760::N-[3-(3-acetylphenyl)-6-[4-(dimethylamino)phenyl]-8-imidazo[1,2-a]pyridinyl]formamide::MLS003124116::N-[3-(3-acetylphenyl)-6-[4-(dimethylamino)phenyl]imidazo[1,2-a]pyridin-8-yl]formamide Melanocortin receptor 4 Homo sapiens >89184 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88517 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88517&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46943760 252660227 C06049 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192685 COc1ccc(cc1OC)-c1cc(NC=O)c2ncc(-c3cccc(c3)C(F)(F)F)n2c1 InChI=1S/C23H18F3N3O3/c1-31-20-7-6-14(10-21(20)32-2)16-9-18(28-13-30)22-27-11-19(29(22)12-16)15-4-3-5-17(8-15)23(24,25)26/h3-13H,1-2H3,(H,28,30) POFAGRZQSHGPRP-UHFFFAOYSA-N 88518 cid_46944097::N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]methanamide::SMR001292781::N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]-8-imidazo[1,2-a]pyridinyl]formamide::MLS003124246::N-[6-(3,4-dimethoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]formamide Melanocortin receptor 4 Homo sapiens 12374 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88518 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88518&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46944097 252660228 C06049 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192686 COc1ccccc1-c1cc(NC=O)c2ncc(-c3cccc(c3)C(F)(F)F)n2c1 InChI=1S/C22H16F3N3O2/c1-30-20-8-3-2-7-17(20)15-10-18(27-13-29)21-26-11-19(28(21)12-15)14-5-4-6-16(9-14)22(23,24)25/h2-13H,1H3,(H,27,29) BFKLRHJTZGMCDU-UHFFFAOYSA-N 88519 SMR001292783::N-[6-(2-methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]-8-imidazo[1,2-a]pyridinyl]formamide::MLS003124247::cid_46948025::N-[6-(2-methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]methanamide::N-[6-(2-methoxyphenyl)-3-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-8-yl]formamide Melanocortin receptor 4 Homo sapiens >89227 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88519&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948025 252660229 C06049 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192687 COc1ccc(cc1OC)-c1cnc2c(NC(C)=O)cc(cn12)-c1ccccc1OC InChI=1S/C24H23N3O4/c1-15(28)26-19-11-17(18-7-5-6-8-21(18)29-2)14-27-20(13-25-24(19)27)16-9-10-22(30-3)23(12-16)31-4/h5-14H,1-4H3,(H,26,28) LVTHBZFJPGVJGT-UHFFFAOYSA-N 88520 SMR001292711::cid_46948136::MLS003124205::N-[3-(3,4-dimethoxyphenyl)-6-(2-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[3-(3,4-dimethoxyphenyl)-6-(2-methoxyphenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::N-[3-(3,4-dimethoxyphenyl)-6-(2-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89194 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88520&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948136 252660230 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192688 NC(Cc1ccc(cc1)C(F)(F)F)c1csc(Nc2nccc(n2)C(F)(F)F)n1 InChI=1S/C17H13F6N5S/c18-16(19,20)10-3-1-9(2-4-10)7-11(24)12-8-29-15(26-12)28-14-25-6-5-13(27-14)17(21,22)23/h1-6,8,11H,7,24H2,(H,25,26,27,28) DRDVQMIHMJPJLH-UHFFFAOYSA-N 88521 4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-N-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3-thiazol-2-amine::SMR001291818::MLS003123761::4-[1-azanyl-2-[4-(trifluoromethyl)phenyl]ethyl]-N-[4-(trifluoromethyl)pyrimidin-2-yl]-1,3-thiazol-2-amine::cid_46948222::4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-N-[4-(trifluoromethyl)-2-pyrimidinyl]-2-thiazolamine::[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]thiazol-2-yl]-[4-(trifluoromethyl)pyrimidin-2-yl]amine Melanocortin receptor 4 Homo sapiens >89177 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88521 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88521&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948222 252660231 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192689 Cc1cc(C)nc(Nc2nc(cs2)C(N)Cc2ccc(Cl)cc2)n1 InChI=1S/C17H18ClN5S/c1-10-7-11(2)21-16(20-10)23-17-22-15(9-24-17)14(19)8-12-3-5-13(18)6-4-12/h3-7,9,14H,8,19H2,1-2H3,(H,20,21,22,23) PJGBSUTYVWCCIU-UHFFFAOYSA-N 88522 MLS003123700::4-[1-azanyl-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine::SMR001291736::4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine::4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethyl-2-pyrimidinyl)-2-thiazolamine::cid_46948249::[4-[1-amino-2-(4-chlorophenyl)ethyl]thiazol-2-yl]-(4,6-dimethylpyrimidin-2-yl)amine Melanocortin receptor 4 Homo sapiens >89220 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88522&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948249 252660232 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192690 CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)c(Cl)c1)-c1cccc(F)c1 InChI=1S/C21H14ClF2N3O/c1-12(28)26-19-9-15(13-3-2-4-16(23)7-13)11-27-20(10-25-21(19)27)14-5-6-18(24)17(22)8-14/h2-11H,1H3,(H,26,28) MOVVDLYGYHYPSA-UHFFFAOYSA-N 88523 cid_46948506::N-[3-(3-chloro-4-fluorophenyl)-6-(3-fluorophenyl)-8-imidazo[1,2-a]pyridinyl]acetamide::MLS003124178::N-[3-(3-chloro-4-fluorophenyl)-6-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]acetamide::N-[3-(3-chloranyl-4-fluoranyl-phenyl)-6-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]ethanamide::SMR001292669::N-[3-(3-chloro-4-fluoro-phenyl)-6-(3-fluorophenyl)imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89188 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88523 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88523&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948506 252660233 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192691 CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)cc1)-c1ccccc1 InChI=1S/C21H16FN3O/c1-14(26)24-19-11-17(15-5-3-2-4-6-15)13-25-20(12-23-21(19)25)16-7-9-18(22)10-8-16/h2-13H,1H3,(H,24,26) CZHWAEAVWDUMSE-UHFFFAOYSA-N 88524 N-[3-(4-fluorophenyl)-6-phenyl-8-imidazo[1,2-a]pyridinyl]acetamide::cid_46948544::SMR001292694::MLS003124305::N-[3-(4-fluorophenyl)-6-phenyl-imidazo[1,2-a]pyridin-8-yl]ethanamide::N-[3-(4-fluorophenyl)-6-phenylimidazo[1,2-a]pyridin-8-yl]acetamide::N-[3-(4-fluorophenyl)-6-phenyl-imidazo[1,2-a]pyridin-8-yl]acetamide Melanocortin receptor 4 Homo sapiens >89178 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88524 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88524&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948544 252660234 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192692 Cc1ccc(cc1)C(=O)Nc1nc(cs1)C(N)Cc1ccc(cc1)C(F)(F)F InChI=1S/C20H18F3N3OS/c1-12-2-6-14(7-3-12)18(27)26-19-25-17(11-28-19)16(24)10-13-4-8-15(9-5-13)20(21,22)23/h2-9,11,16H,10,24H2,1H3,(H,25,26,27) BCUYPBIODKWPRI-UHFFFAOYSA-N 88525 cid_46948559::N-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-2-thiazolyl]-4-methylbenzamide::N-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]-1,3-thiazol-2-yl]-4-methylbenzamide::N-[4-[1-azanyl-2-[4-(trifluoromethyl)phenyl]ethyl]-1,3-thiazol-2-yl]-4-methyl-benzamide::N-[4-[1-amino-2-[4-(trifluoromethyl)phenyl]ethyl]thiazol-2-yl]-4-methyl-benzamide Melanocortin receptor 4 Homo sapiens >89214 PubChem 10.7270/Q2QC0233 aid602263 PubChem, PC 2/16/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88525 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88525&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 46948559 252660235 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6