BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 192863 COC(=O)CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)N1CCCCC1 InChI=1S/C16H19N3O5S2/c1-23-14(20)11-25-16-18-17-15(24-16)12-5-7-13(8-6-12)26(21,22)19-9-3-2-4-10-19/h5-8H,2-4,9-11H2,1H3 HHHMVJQXDSOUCL-UHFFFAOYSA-N 88569 methyl 2-[[5-(4-piperidin-1-ylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetate::2-[[5-[4-(1-piperidinylsulfonyl)phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester::MLS000074183::cid_648859::{5-[4-(Piperidine-1-sulfonyl)-phenyl]-[1,3,4]oxadiazol-2-ylsulfanyl}-acetic acid methyl ester::SMR000002587::methyl 2-[[5-(4-piperidin-1-ylsulfonylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoate::2-[[5-(4-piperidinosulfonylphenyl)-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester Melanocortin receptor 4 Homo sapiens >64562 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88569 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88569&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 648859 252660238 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192864 CCOC(=O)CSc1nnc(o1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 InChI=1S/C19H19N3O5S2/c1-3-26-17(23)12-28-19-21-20-18(27-19)14-6-8-15(9-7-14)22-29(24,25)16-10-4-13(2)5-11-16/h4-11,22H,3,12H2,1-2H3 DHMMBOPJUQCCRQ-UHFFFAOYSA-N 88570 SMR000002544::ethyl 2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoate::cid_654288::2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl ester::ethyl 2-[[5-[4-[(4-methylphenyl)sulfonylamino]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetate::MLS000072972::{5-[4-(Toluene-4-sulfonylamino)-phenyl]-[1,3,4]oxadiazol-2-ylsulfanyl}-acetic acid ethyl ester::2-[[5-[4-(tosylamino)phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl ester Melanocortin receptor 4 Homo sapiens >64551 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88570 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88570&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 654288 252660239 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192865 N=c1n(CCCn2ccnc2)cnc2n(Cc3ccccc3)c(c(-c3ccccc3)c12)-c1ccccc1 InChI=1S/C31H28N6/c32-30-28-27(25-13-6-2-7-14-25)29(26-15-8-3-9-16-26)37(21-24-11-4-1-5-12-24)31(28)34-23-36(30)19-10-18-35-20-17-33-22-35/h1-9,11-17,20,22-23,32H,10,18-19,21H2 VWNVIJBBANKZES-UHFFFAOYSA-N 88571 7-benzyl-3-(3-imidazol-1-ylpropyl)-5,6-diphenylpyrrolo[2,3-d]pyrimidin-4-imine::MLS000036694::3-[3-(1-imidazolyl)propyl]-5,6-diphenyl-7-(phenylmethyl)-4-pyrrolo[2,3-d]pyrimidinimine::3-(3-imidazol-1-ylpropyl)-5,6-diphenyl-7-(phenylmethyl)pyrrolo[2,3-d]pyrimidin-4-imine::SMR000037239::cid_661535::[7-benzyl-3-(3-imidazol-1-ylpropyl)-5,6-diphenyl-pyrrolo[2,3-d]pyrimidin-4-ylidene]amine Melanocortin receptor 4 Homo sapiens >64586 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88571 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88571&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 661535 252660240 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192866 CN(C)CCCN1C(C(C(=O)c2cc3ccccc3o2)C(=O)C1=O)c1ccccn1 InChI=1S/C23H23N3O4/c1-25(2)12-7-13-26-20(16-9-5-6-11-24-16)19(22(28)23(26)29)21(27)18-14-15-8-3-4-10-17(15)30-18/h3-6,8-11,14,19-20H,7,12-13H2,1-2H3 PCDGLMUISJASFP-UHFFFAOYSA-N 88572 SMR000042530::MLS000077870::3-(1-benzofuran-2-ylcarbonyl)-1-[3-(dimethylamino)propyl]-4-oxidanyl-2-pyridin-2-yl-2H-pyrrol-5-one::cid_661871::3-(1-benzofuran-2-carbonyl)-1-[3-(dimethylamino)propyl]-4-hydroxy-2-pyridin-2-yl-2H-pyrrol-5-one::3-[2-benzofuranyl(oxo)methyl]-1-[3-(dimethylamino)propyl]-4-hydroxy-2-(2-pyridinyl)-2H-pyrrol-5-one::4-(benzofuran-2-carbonyl)-1-[3-(dimethylamino)propyl]-3-hydroxy-5-(2-pyridyl)-3-pyrrolin-2-one Melanocortin receptor 4 Homo sapiens >64600 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88572 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88572&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899117 252660241 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192867 COc1ccc(cc1)-n1c(SC2CCOC2=O)nc2ccccc12 InChI=1S/C18H16N2O3S/c1-22-13-8-6-12(7-9-13)20-15-5-3-2-4-14(15)19-18(20)24-16-10-11-23-17(16)21/h2-9,16H,10-11H2,1H3 FAIZAGVFKFRNMX-UHFFFAOYSA-N 88573 3-[[1-(4-methoxyphenyl)-2-benzimidazolyl]thio]-2-oxolanone::cid_2998526::SMR000062310::3-[1-(4-methoxyphenyl)benzimidazol-2-yl]sulfanyloxolan-2-one::MLS000096504::3-[[1-(4-methoxyphenyl)benzimidazol-2-yl]thio]tetrahydrofuran-2-one Melanocortin receptor 4 Homo sapiens >64556 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88573 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88573&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2998526 252660242 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192868 O=C1N(SC2CCCCC2)C(=O)c2ccccc12 InChI=1S/C14H15NO2S/c16-13-11-8-4-5-9-12(11)14(17)15(13)18-10-6-2-1-3-7-10/h4-5,8-10H,1-3,6-7H2 UEZWYKZHXASYJN-UHFFFAOYSA-N 88574 MLS000054273::2-(cyclohexylthio)isoindole-1,3-dione::cid_28777::SMR000066211::2-cyclohexylsulfanylisoindole-1,3-dione::N-(CYCLOHEXYLTHIO)PHTHALIMIDE::2-(cyclohexylthio)isoindoline-1,3-quinone Melanocortin receptor 4 Homo sapiens 62013 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88574 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88574&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 28777 252660243 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192869 COc1cc2c(cc1NC(=O)CN1C(=O)NC3(CCc4ccccc34)C1=O)oc1ccccc21 InChI=1S/C26H21N3O5/c1-33-22-12-17-16-7-3-5-9-20(16)34-21(17)13-19(22)27-23(30)14-29-24(31)26(28-25(29)32)11-10-15-6-2-4-8-18(15)26/h2-9,12-13H,10-11,14H2,1H3,(H,27,30)(H,28,32) IMYGPCCRJQSNBJ-UHFFFAOYSA-N 50816 cid_2999672::SMR000063903::MLS000097710::2-(2',5'-dioxo-1'-spiro[1,2-dihydroindene-3,4'-imidazolidine]yl)-N-(2-methoxy-3-dibenzofuranyl)acetamide::2-[2',5'-bis(oxidanylidene)spiro[1,2-dihydroindene-3,4'-imidazolidine]-1'-yl]-N-(2-methoxydibenzofuran-3-yl)ethanamide::2-(2',5'-dioxospiro[1,2-dihydroindene-3,4'-imidazolidine]-1'-yl)-N-(2-methoxydibenzofuran-3-yl)acetamide::2-(2,5-diketospiro[imidazolidine-4,1'-indane]-1-yl)-N-(2-methoxydibenzofuran-3-yl)acetamide Melanocortin receptor 4 Homo sapiens >64554 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50816 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50816&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2999672 252631068 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192870 Clc1ccc2nc3CCCCc3c(SCC(=O)N3CCN(CC3)C(=O)c3ccco3)c2c1 InChI=1S/C24H24ClN3O3S/c25-16-7-8-20-18(14-16)23(17-4-1-2-5-19(17)26-20)32-15-22(29)27-9-11-28(12-10-27)24(30)21-6-3-13-31-21/h3,6-8,13-14H,1-2,4-5,9-12,15H2 GUPHTHSGBNNSPA-UHFFFAOYSA-N 88575 7-chloro-9-({2-[4-(2-furoyl)piperazin-1-yl]-2-oxoethyl}thio)-1,2,3,4-tetrahydroacridine::2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-1-[4-(furan-2-carbonyl)piperazin-1-yl]ethanone::2-[(7-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-1-[4-(furan-2-ylcarbonyl)piperazin-1-yl]ethanone::MLS000045516::SMR000027273::cid_3239595::2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-1-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]ethanone::2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-1-[4-(2-furoyl)piperazino]ethanone Melanocortin receptor 4 Homo sapiens >64599 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88575 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88575&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3239595 252660244 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192871 O=C1OCCC1Sc1nc2ccccc2n1Cc1ccccc1 InChI=1S/C18H16N2O2S/c21-17-16(10-11-22-17)23-18-19-14-8-4-5-9-15(14)20(18)12-13-6-2-1-3-7-13/h1-9,16H,10-12H2 PASDTLWASOQQGV-UHFFFAOYSA-N 88576 cid_2948635::3-(1-benzylbenzimidazol-2-yl)sulfanyloxolan-2-one::3-[(1-benzyl-1H-benzimidazol-2-yl)thio]dihydro-2(3H)-furanone::3-[[1-(phenylmethyl)-2-benzimidazolyl]thio]-2-oxolanone::MLS000063362::SMR000075066::3-[1-(phenylmethyl)benzimidazol-2-yl]sulfanyloxolan-2-one::3-[(1-benzylbenzimidazol-2-yl)thio]tetrahydrofuran-2-one Melanocortin receptor 4 Homo sapiens 10869 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88576 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88576&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2948635 252660245 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192872 Brc1ccc(c2nsnc12)S(=O)(=O)N1CCOCC1 InChI=1S/C10H10BrN3O3S2/c11-7-1-2-8(10-9(7)12-18-13-10)19(15,16)14-3-5-17-6-4-14/h1-2H,3-6H2 OGEBDBPRSXCLNF-UHFFFAOYSA-N 88577 4-[(4-bromo-2,1,3-benzothiadiazol-7-yl)sulfonyl]morpholine::4-[(4-bromanyl-2,1,3-benzothiadiazol-7-yl)sulfonyl]morpholine::4-bromo-7-(4-morpholinylsulfonyl)-2,1,3-benzothiadiazole::cid_1224769::SMR000077641::MLS000064779::4-(7-bromopiazthiol-4-yl)sulfonylmorpholine Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88577 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88577&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1224769 252660246 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192873 CCN(CC)c1ccc2c(c1)oc(=O)c1c(Cl)cc(=O)oc21 InChI=1S/C16H14ClNO4/c1-3-18(4-2)9-5-6-10-12(7-9)21-16(20)14-11(17)8-13(19)22-15(10)14/h5-8H,3-4H2,1-2H3 ZDKLLWHULUEJNW-UHFFFAOYSA-N 40530 4-chloro-8-(diethylamino)-2H,5H-pyrano[3,2-c]chromene-2,5-dione::MLS000059194::4-chloro-8-(diethylamino)pyrano[3,2-c]chromene-2,5-dione::cid_756377::4-chloranyl-8-(diethylamino)pyrano[3,2-c]chromene-2,5-dione::4-chloro-8-(diethylamino)pyrano[3,2-c][1]benzopyran-2,5-dione::SMR000069566::4-chloro-8-(diethylamino)pyrano[3,2-c]chromene-2,5-quinone Melanocortin receptor 4 Homo sapiens >64598 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40530 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40530&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 756377 252621352 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192874 CCOC(=O)c1ccc(cc1)\N=c1/sc(cc(=O)n1Cc1ccco1)C(=O)OC InChI=1S/C20H18N2O6S/c1-3-27-18(24)13-6-8-14(9-7-13)21-20-22(12-15-5-4-10-28-15)17(23)11-16(29-20)19(25)26-2/h4-11H,3,12H2,1-2H3 VWYKBRYDSJBXQE-UHFFFAOYSA-N 68588 methyl 2-(4-ethoxycarbonylphenyl)imino-3-(furan-2-ylmethyl)-4-oxidanylidene-1,3-thiazine-6-carboxylate::SMR000095393::methyl 2-(4-ethoxycarbonylphenyl)imino-3-(furan-2-ylmethyl)-4-oxo-1,3-thiazine-6-carboxylate::cid_1518343::2-(4-ethoxycarbonylphenyl)imino-3-(2-furanylmethyl)-4-oxo-1,3-thiazine-6-carboxylic acid methyl ester::MLS000118452::2-(4-carbethoxyphenyl)imino-3-(2-furfuryl)-4-keto-1,3-thiazine-6-carboxylic acid methyl ester Melanocortin receptor 4 Homo sapiens >7167 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68588 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68588&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1518343 252646764 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192875 O=C(CSc1nc2CCCCCc2cc1C#N)Nc1nccs1 InChI=1S/C16H16N4OS2/c17-9-12-8-11-4-2-1-3-5-13(11)19-15(12)23-10-14(21)20-16-18-6-7-22-16/h6-8H,1-5,10H2,(H,18,20,21) HZAAPRANCMOVML-UHFFFAOYSA-N 48173 MLS000108418::SMR000015755::2-[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)sulfanyl]-N-(1,3-thiazol-2-yl)ethanamide::2-[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio]-N-(2-thiazolyl)acetamide::2-[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide::cid_2140504::2-[(3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio]-N-thiazol-2-yl-acetamide Melanocortin receptor 4 Homo sapiens 11811 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48173&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2140504 252628471 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192876 COC(=O)C1CSC(CC(=O)Nc2sc3CCCCc3c2C(=O)OC)C(=O)N1 InChI=1S/C18H22N2O6S2/c1-25-17(23)10-8-27-12(15(22)19-10)7-13(21)20-16-14(18(24)26-2)9-5-3-4-6-11(9)28-16/h10,12H,3-8H2,1-2H3,(H,19,22)(H,20,21) ZQVJVCHBKJBYEM-UHFFFAOYSA-N 39570 MLS000111734::methyl 6-[2-[(3-methoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-thiomorpholine-3-carboxylate::cid_2891928::SMR000107656::6-[2-[(3-methoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxoethyl]-5-oxo-3-thiomorpholinecarboxylic acid methyl ester::methyl 6-[2-[(3-methoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxoethyl]-5-oxothiomorpholine-3-carboxylate::6-[2-[(3-carbomethoxy-4,5,6,7-tetrahydrobenzothiophen-2-yl)amino]-2-keto-ethyl]-5-keto-thiomorpholine-3-carboxylic acid methyl ester Melanocortin receptor 4 Homo sapiens >64586 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39570 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39570&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2891928 252620461 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192877 O=C(N1CCN(CC1)c1nc(-c2ccccc2)c2CCCCc2c1C#N)c1ccco1 InChI=1S/C25H24N4O2/c26-17-21-19-9-4-5-10-20(19)23(18-7-2-1-3-8-18)27-24(21)28-12-14-29(15-13-28)25(30)22-11-6-16-31-22/h1-3,6-8,11,16H,4-5,9-10,12-15H2 QGQNUHXQNSGZIM-UHFFFAOYSA-N 88578 3-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile::cid_1321203::SMR000108371::MLS000112457::3-[4-(furan-2-carbonyl)piperazin-1-yl]-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile::3-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile::3-[4-(2-furoyl)piperazino]-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile Melanocortin receptor 4 Homo sapiens >64565 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88578 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88578&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1321203 252660247 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192878 CCOC(=O)CSc1nc2ccc(Nc3nc(nc(n3)N3CCOCC3)N3CCOCC3)cc2s1 InChI=1S/C22H27N7O4S2/c1-2-33-18(30)14-34-22-24-16-4-3-15(13-17(16)35-22)23-19-25-20(28-5-9-31-10-6-28)27-21(26-19)29-7-11-32-12-8-29/h3-4,13H,2,5-12,14H2,1H3,(H,23,25,26,27) WFVTVSQVLLMKKM-UHFFFAOYSA-N 52221 2-[[6-[[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]amino]-1,3-benzothiazol-2-yl]thio]acetic acid ethyl ester::ethyl 2-[[6-[(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)amino]-1,3-benzothiazol-2-yl]sulfanyl]ethanoate::ethyl 2-[[6-[(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)amino]-1,3-benzothiazol-2-yl]sulfanyl]acetate::MLS000548960::cid_3428335::ethyl ({6-[(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)amino]-1,3-benzothiazol-2-yl}sulfanyl)acetate::SMR000115267::2-[[6-[(4,6-dimorpholino-s-triazin-2-yl)amino]-1,3-benzothiazol-2-yl]thio]acetic acid ethyl ester Melanocortin receptor 4 Homo sapiens >64582 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52221&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3428335 252632371 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192879 COC(=O)CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)NCc1ccccc1Cl InChI=1S/C18H16ClN3O5S2/c1-26-16(23)11-28-18-22-21-17(27-18)12-6-8-14(9-7-12)29(24,25)20-10-13-4-2-3-5-15(13)19/h2-9,20H,10-11H2,1H3 GNTWJZLJFZWFCH-UHFFFAOYSA-N 88579 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester::methyl 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoate::MLS000122835::cid_1155311::{5-[4-(2-Chloro-benzylsulfamoyl)-phenyl]-[1,3,4]oxadiazol-2-ylsulfanyl}-acetic acid methyl ester::SMR000123462::methyl 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetate::2-[[5-[4-[(2-chlorobenzyl)sulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88579 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88579&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1155311 252660248 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192880 Clc1cc(Cl)c(cc1C(=O)Nc1nccs1)S(=O)(=O)N1CCOCC1 InChI=1S/C14H13Cl2N3O4S2/c15-10-8-11(16)12(25(21,22)19-2-4-23-5-3-19)7-9(10)13(20)18-14-17-1-6-24-14/h1,6-8H,2-5H2,(H,17,18,20) SYPVSDULPPCGLN-UHFFFAOYSA-N 88580 2,4-Dichloro-5-(morpholine-4-sulfonyl)-N-thiazol-2-yl-benzamide::cid_1107087::2,4-bis(chloranyl)-5-morpholin-4-ylsulfonyl-N-(1,3-thiazol-2-yl)benzamide::2,4-dichloro-5-(4-morpholinylsulfonyl)-N-(2-thiazolyl)benzamide::MLS000123976::SMR000124476::2,4-dichloro-5-morpholin-4-ylsulfonyl-N-(1,3-thiazol-2-yl)benzamide::2,4-dichloro-5-morpholinosulfonyl-N-thiazol-2-yl-benzamide Melanocortin receptor 4 Homo sapiens >64563 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88580 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88580&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1107087 252660249 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192881 CC(C)C1C(N(C)C(CC1(O)c1ccccc1)c1ccccc1)c1ccccc1 InChI=1S/C27H31NO/c1-20(2)25-26(22-15-9-5-10-16-22)28(3)24(21-13-7-4-8-14-21)19-27(25,29)23-17-11-6-12-18-23/h4-18,20,24-26,29H,19H2,1-3H3 XANBEVHQLOSTKB-UHFFFAOYSA-N 57063 MLS000525447::1-methyl-2,4,6-triphenyl-3-propan-2-ylpiperidin-4-ol::1-methyl-2,4,6-triphenyl-3-propan-2-yl-4-piperidinol::SMR000115921::cid_3089037::1-methyl-2,4,6-triphenyl-3-propan-2-yl-piperidin-4-ol::3-isopropyl-1-methyl-2,4,6-triphenyl-piperidin-4-ol Melanocortin receptor 4 Homo sapiens >64564 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57063 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57063&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3089037 252637001 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192882 C(Cn1c(NCc2nc3ccccc3n2Cc2ccccc2)nc2ccccc12)N1CCCCC1 InChI=1S/C29H32N6/c1-3-11-23(12-4-1)22-35-27-16-8-5-13-24(27)31-28(35)21-30-29-32-25-14-6-7-15-26(25)34(29)20-19-33-17-9-2-10-18-33/h1,3-8,11-16H,2,9-10,17-22H2,(H,30,32) MMOBBISAVIKZPP-UHFFFAOYSA-N 43798 cid_1043331::N-[(1-benzylbenzimidazol-2-yl)methyl]-1-(2-piperidin-1-ylethyl)benzimidazol-2-amine::MLS-0083130.0001::N-[[1-(phenylmethyl)benzimidazol-2-yl]methyl]-1-(2-piperidin-1-ylethyl)benzimidazol-2-amine::N-[[1-(phenylmethyl)-2-benzimidazolyl]methyl]-1-[2-(1-piperidinyl)ethyl]-2-benzimidazolamine::(1-benzylbenzimidazol-2-yl)methyl-[1-(2-piperidinoethyl)benzimidazol-2-yl]amine Melanocortin receptor 4 Homo sapiens >64583 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43798 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43798&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1043331 252624473 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192883 CCOc1ccc2nc(NC(=O)C3CCCN(C3)S(=O)(=O)c3cccc4nonc34)sc2c1 InChI=1S/C21H21N5O5S2/c1-2-30-14-8-9-15-17(11-14)32-21(22-15)23-20(27)13-5-4-10-26(12-13)33(28,29)18-7-3-6-16-19(18)25-31-24-16/h3,6-9,11,13H,2,4-5,10,12H2,1H3,(H,22,23,27) PUVRBNQNWNIJNA-UHFFFAOYSA-N 88581 cid_9550171::MLS000521743::1-(2,1,3-benzoxadiazol-4-ylsulfonyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)piperidine-3-carboxamide::1-(2,1,3-benzoxadiazol-4-ylsulfonyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-piperidinecarboxamide::SMR000132151::1-benzofurazan-4-ylsulfonyl-N-(6-ethoxy-1,3-benzothiazol-2-yl)nipecotamide Melanocortin receptor 4 Homo sapiens >64622 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88581 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88581&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9550171 252660250 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192884 [O-][N+](=O)c1cc(ccc1Sc1nc2ccccc2[nH]1)S(=O)(=O)C(F)(F)F InChI=1S/C14H8F3N3O4S2/c15-14(16,17)26(23,24)8-5-6-12(11(7-8)20(21)22)25-13-18-9-3-1-2-4-10(9)19-13/h1-7H,(H,18,19) CNXPXYYJQNDCLC-UHFFFAOYSA-N 57129 SMR000141130::cid_1336753::2-[[2-nitro-4-(trifluoromethylsulfonyl)phenyl]thio]-1H-benzimidazole::2-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]sulfanyl-1H-benzimidazole::2-({2-nitro-4-[(trifluoromethyl)sulfonyl]phenyl}thio)-1H-benzimidazole::MLS000533685::2-[(2-nitro-4-triflyl-phenyl)thio]-1H-benzimidazole Melanocortin receptor 4 Homo sapiens 7647 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57129 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57129&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1336753 252637067 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192885 Oc1ccc(cc1)N1C(=O)\C(=C\c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1 |c:23| InChI=1S/C23H16N2O4/c26-21-12-10-19(11-13-21)24-22(17-4-2-1-3-5-17)15-18(23(24)27)14-16-6-8-20(9-7-16)25(28)29/h1-15,26H GQDXXWHROQBAHL-UHFFFAOYSA-N 55412 (3E)-1-(4-hydroxyphenyl)-3-[(4-nitrophenyl)methylidene]-5-phenyl-2-pyrrolone::(3E)-1-(4-hydroxyphenyl)-3-[(4-nitrophenyl)methylidene]-5-phenyl-pyrrol-2-one::(3E)-1-(4-hydroxyphenyl)-3-[(4-nitrophenyl)methylidene]-5-phenylpyrrol-2-one::cid_5346268::SMR000131790::MLS000521382::(3E)-1-(4-hydroxyphenyl)-3-(4-nitrobenzylidene)-5-phenyl-2-pyrrolin-2-one Melanocortin receptor 4 Homo sapiens >64564 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55412 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55412&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5346268 252635409 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192886 CC1=NOC(=O)\C1=C\c1ccc(o1)-c1ccc(Cl)cc1 |t:1| InChI=1S/C15H10ClNO3/c1-9-13(15(18)20-17-9)8-12-6-7-14(19-12)10-2-4-11(16)5-3-10/h2-8H,1H3 OZCTZEQRPXUHPT-UHFFFAOYSA-N 64843 (4E)-4-[[5-(4-chlorophenyl)furan-2-yl]methylidene]-3-methyl-1,2-oxazol-5-one::(4E)-4-[[5-(4-chlorophenyl)-2-furanyl]methylidene]-3-methyl-5-isoxazolone::MLS000519119::SMR000129538::cid_5291838::(4E)-4-[[5-(4-chlorophenyl)-2-furyl]methylene]-3-methyl-2-isoxazolin-5-one Melanocortin receptor 4 Homo sapiens 8054 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64843 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64843&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5291838 252643801 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192887 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc1ccc(Cl)cc1)C(F)(F)F InChI=1S/C15H9ClF3NO5S/c16-10-2-4-11(5-3-10)25-14(21)8-26(24)13-6-1-9(15(17,18)19)7-12(13)20(22)23/h1-7H,8H2 QYOVKDKSKVPVHI-UHFFFAOYSA-N 88582 4-chlorophenyl {[2-nitro-4-(trifluoromethyl)phenyl]sulfinyl}acetate::(4-chlorophenyl) 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylethanoate::(4-chlorophenyl) 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetate::MLS000536845::SMR000143482::cid_2203170::2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetic acid (4-chlorophenyl) ester Melanocortin receptor 4 Homo sapiens >64578 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88582 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88582&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2203170 252660251 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192888 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc1ccccc1)C(F)(F)F InChI=1S/C15H10F3NO5S/c16-15(17,18)10-6-7-13(12(8-10)19(21)22)25(23)9-14(20)24-11-4-2-1-3-5-11/h1-8H,9H2 DWRLEMDHSFGCKK-UHFFFAOYSA-N 66351 phenyl {[2-nitro-4-(trifluoromethyl)phenyl]sulfinyl}acetate::phenyl 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylethanoate::MLS000535532::cid_1189526::phenyl 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetate::SMR000142967::2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetic acid phenyl ester Melanocortin receptor 4 Homo sapiens 13468 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66351&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1189526 252644676 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192889 COC(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)n1nc(C)c(Br)c1C InChI=1S/C13H11BrCl2N2O4S/c1-6-12(14)7(2)18(17-6)23(20,21)11-4-8(13(19)22-3)9(15)5-10(11)16/h4-5H,1-3H3 VRCBXMSAURUAFF-UHFFFAOYSA-N 57188 5-(4-Bromo-3,5-dimethyl-pyrazole-1-sulfonyl)-2,4-dichloro-benzoic acid methyl ester::methyl 5-(4-bromanyl-3,5-dimethyl-pyrazol-1-yl)sulfonyl-2,4-bis(chloranyl)benzoate::MLS000552104::SMR000145828::cid_1895567::5-[(4-bromo-3,5-dimethyl-1-pyrazolyl)sulfonyl]-2,4-dichlorobenzoic acid methyl ester::methyl 5-(4-bromo-3,5-dimethylpyrazol-1-yl)sulfonyl-2,4-dichlorobenzoate::5-(4-bromo-3,5-dimethyl-pyrazol-1-yl)sulfonyl-2,4-dichloro-benzoic acid methyl ester Melanocortin receptor 4 Homo sapiens >64590 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57188 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57188&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1895567 252637124 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192890 CC(C)Cc1nc2oc3c(Cl)ncnc3c2c2CCCc12 InChI=1S/C16H16ClN3O/c1-8(2)6-11-9-4-3-5-10(9)12-13-14(21-16(12)20-11)15(17)19-7-18-13/h7-8H,3-6H2,1-2H3 KJJKBBDXEGRDQY-UHFFFAOYSA-N 67173 MLS000559126::7-Chloro-4-isobutyl-2,3-dihydro-1H-6-oxa-5,8,10-triaza-cyclopenta[c]fluorene::SMR000149442::cid_2027229 Melanocortin receptor 4 Homo sapiens >64565 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67173&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2027229 242053453 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192891 Clc1ccc2n(Cc3ccccc3)c(SC3CCOC3=O)nc2c1 InChI=1S/C18H15ClN2O2S/c19-13-6-7-15-14(10-13)20-18(24-16-8-9-23-17(16)22)21(15)11-12-4-2-1-3-5-12/h1-7,10,16H,8-9,11H2 RLWJVMPRIWVGGZ-UHFFFAOYSA-N 88583 SMR000154086::MLS000567329::3-(1-benzyl-5-chlorobenzimidazol-2-yl)sulfanyloxolan-2-one::cid_4884388::3-[[5-chloro-1-(phenylmethyl)-2-benzimidazolyl]thio]-2-oxolanone::3-[5-chloranyl-1-(phenylmethyl)benzimidazol-2-yl]sulfanyloxolan-2-one::3-[(1-benzyl-5-chloro-benzimidazol-2-yl)thio]tetrahydrofuran-2-one Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88583 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88583&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4884388 252660252 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192892 Clc1cc(Cl)c(cc1C(=O)Nc1nnc(s1)-c1ccccc1)S(=O)(=O)N1CCOCC1 InChI=1S/C19H16Cl2N4O4S2/c20-14-11-15(21)16(31(27,28)25-6-8-29-9-7-25)10-13(14)17(26)22-19-24-23-18(30-19)12-4-2-1-3-5-12/h1-5,10-11H,6-9H2,(H,22,24,26) IKIUPKGKSCTCCV-UHFFFAOYSA-N 45499 2,4-dichloro-5-morpholin-4-ylsulfonyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide::2,4-dichloro-5-(4-morpholinylsulfonyl)-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide::SMR000135701::MLS000530723::cid_1322381::2,4-bis(chloranyl)-5-morpholin-4-ylsulfonyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide::2,4-dichloro-5-morpholinosulfonyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzamide Melanocortin receptor 4 Homo sapiens >2392 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=45499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=45499&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1322381 252626097 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192893 CC(C)(C)C(=O)COC(=O)CNC(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C21H23NO5/c1-21(2,3)18(23)14-26-19(24)13-22-20(25)15-9-11-17(12-10-15)27-16-7-5-4-6-8-16/h4-12H,13-14H2,1-3H3,(H,22,25) DTUBOEDCMYLRHB-UHFFFAOYSA-N 56428 cid_3961056::SMR000150162::(3,3-dimethyl-2-oxidanylidene-butyl) 2-[(4-phenoxyphenyl)carbonylamino]ethanoate::2-[[oxo-(4-phenoxyphenyl)methyl]amino]acetic acid (3,3-dimethyl-2-oxobutyl) ester::MLS000570134::(3,3-dimethyl-2-oxobutyl) 2-[(4-phenoxybenzoyl)amino]acetate::2-[(4-phenoxybenzoyl)amino]acetic acid (2-keto-3,3-dimethyl-butyl) ester Melanocortin receptor 4 Homo sapiens >64578 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=56428 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=56428&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3961056 252636393 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192894 O=C(CNC(=O)c1ccc(Oc2ccccc2)cc1)OC1CCCCC1=O InChI=1S/C21H21NO5/c23-18-8-4-5-9-19(18)27-20(24)14-22-21(25)15-10-12-17(13-11-15)26-16-6-2-1-3-7-16/h1-3,6-7,10-13,19H,4-5,8-9,14H2,(H,22,25) ITHIIPPDVQTGRB-UHFFFAOYSA-N 88584 SMR000150713::MLS000571049::cid_4235517::2-[[oxo-(4-phenoxyphenyl)methyl]amino]acetic acid (2-oxocyclohexyl) ester::(2-oxidanylidenecyclohexyl) 2-[(4-phenoxyphenyl)carbonylamino]ethanoate::(2-oxocyclohexyl) 2-[(4-phenoxybenzoyl)amino]acetate::2-[(4-phenoxybenzoyl)amino]acetic acid (2-ketocyclohexyl) ester Melanocortin receptor 4 Homo sapiens >64594 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88584 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88584&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4235517 252660253 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192895 CC(C)C(=O)NC(=S)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C19H19N3OS2/c1-11(2)17(23)22-19(24)20-14-7-5-13(6-8-14)18-21-15-9-4-12(3)10-16(15)25-18/h4-11H,1-3H3,(H2,20,22,23,24) KLFJSJWKLKGLIU-UHFFFAOYSA-N 88585 MLS000538827::2-methyl-N-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]carbamothioyl]propanamide::2-methyl-N-[[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-sulfanylidenemethyl]propanamide::N-isobutyryl-N'-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]thiourea::cid_1792505::SMR000160681::2-methyl-N-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]thiocarbamoyl]propionamide Melanocortin receptor 4 Homo sapiens >64578 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88585 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88585&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1792505 252660254 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192896 CCOC(=O)c1c(C)c(sc1NC(=O)C1c2ccccc2Oc2ccccc12)C(N)=O InChI=1S/C23H20N2O5S/c1-3-29-23(28)17-12(2)19(20(24)26)31-22(17)25-21(27)18-13-8-4-6-10-15(13)30-16-11-7-5-9-14(16)18/h4-11,18H,3H2,1-2H3,(H2,24,26)(H,25,27) KMOQILYLFZKRMB-UHFFFAOYSA-N 88586 cid_1221905::ethyl 5-carbamoyl-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylate::MLS000544761::SMR000159387::ethyl 5-(aminocarbonyl)-4-methyl-2-[(9H-xanthen-9-ylcarbonyl)amino]-3-thiophenecarboxylate::ethyl 5-aminocarbonyl-4-methyl-2-(9H-xanthen-9-ylcarbonylamino)thiophene-3-carboxylate::5-carbamoyl-4-methyl-2-[[oxo(9H-xanthen-9-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl ester::5-carbamoyl-4-methyl-2-(9H-xanthene-9-carbonylamino)thiophene-3-carboxylic acid ethyl ester Melanocortin receptor 4 Homo sapiens >21522 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88586 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88586&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1221905 252660255 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192897 COc1cc(CN=Nc2nc(Nc3ccc(C)cc3)nc(n2)-n2nc(C)cc2C)cc(OC)c1OC |w:7.7| InChI=1S/C25H28N8O3/c1-15-7-9-19(10-8-15)27-23-28-24(30-25(29-23)33-17(3)11-16(2)32-33)31-26-14-18-12-20(34-4)22(36-6)21(13-18)35-5/h7-13H,14H2,1-6H3,(H,27,28,29,30) NGHIESOVAOHHBW-UHFFFAOYSA-N 57286 cid_4625913::6-(3,5-dimethylpyrazol-1-yl)-N4-(4-methylphenyl)-N2-[(3,4,5-trimethoxyphenyl)methylideneamino]-1,3,5-triazine-2,4-diamine::MLS000544406::6-(3,5-dimethylpyrazol-1-yl)-4-N-(4-methylphenyl)-2-N-[(3,4,5-trimethoxyphenyl)methylideneamino]-1,3,5-triazine-2,4-diamine::3,4,5-trimethoxybenzaldehyde [4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(4-toluidino)-1,3,5-triazin-2-yl]hydrazone::SMR000164268::[4-(3,5-dimethylpyrazol-1-yl)-6-(p-toluidino)-s-triazin-2-yl]-[(E)-(3,4,5-trimethoxybenzylidene)amino]amine::6-(3,5-dimethyl-1-pyrazolyl)-N4-(4-methylphenyl)-N2-[(3,4,5-trimethoxyphenyl)methylideneamino]-1,3,5-triazine-2,4-diamine::[4-(3,5-dimethylpyrazol-1-yl)-6-(p-toluidino)-s-triazin-2-yl]-[(3,4,5-trimethoxybenzylidene)amino]amine Melanocortin receptor 4 Homo sapiens >64572 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57286 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57286&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91897298 252637218 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192898 CC(C)(CNC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O)CNC(=O)c1ccc(c(Cl)c1)[N+]([O-])=O InChI=1S/C19H18Cl2N4O6/c1-19(2,9-22-17(26)11-3-5-15(24(28)29)13(20)7-11)10-23-18(27)12-4-6-16(25(30)31)14(21)8-12/h3-8H,9-10H2,1-2H3,(H,22,26)(H,23,27) QMUXASORLUENRK-UHFFFAOYSA-N 61464 MLS000545868::3-chloro-N-[3-[(3-chloro-4-nitrobenzoyl)amino]-2,2-dimethylpropyl]-4-nitrobenzamide::3-chloranyl-N-[3-[(3-chloranyl-4-nitro-phenyl)carbonylamino]-2,2-dimethyl-propyl]-4-nitro-benzamide::cid_1746062::SMR000159469::3-chloro-N-[3-[[(3-chloro-4-nitrophenyl)-oxomethyl]amino]-2,2-dimethylpropyl]-4-nitrobenzamide::3-chloro-N-[3-({3-chloro-4-nitrobenzoyl}amino)-2,2-dimethylpropyl]-4-nitrobenzamide::3-chloro-N-[3-[(3-chloro-4-nitro-benzoyl)amino]-2,2-dimethyl-propyl]-4-nitro-benzamide Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61464&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1746062 252640619 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192899 Clc1ccc2sc(NC(=O)C3CCCN(C3)S(=O)(=O)c3cccc4cccnc34)nc2c1 InChI=1S/C22H19ClN4O3S2/c23-16-8-9-18-17(12-16)25-22(31-18)26-21(28)15-6-3-11-27(13-15)32(29,30)19-7-1-4-14-5-2-10-24-20(14)19/h1-2,4-5,7-10,12,15H,3,6,11,13H2,(H,25,26,28) UWLQCJJVPZRTNH-UHFFFAOYSA-N 88588 cid_5210018::N-(5-chloranyl-1,3-benzothiazol-2-yl)-1-quinolin-8-ylsulfonyl-piperidine-3-carboxamide::N-(5-chloro-1,3-benzothiazol-2-yl)-1-quinolin-8-ylsulfonylpiperidine-3-carboxamide::N-(5-chloro-1,3-benzothiazol-2-yl)-1-(8-quinolinylsulfonyl)-3-piperidinecarboxamide::MLS000523089::SMR000128354::N-(5-chloro-1,3-benzothiazol-2-yl)-1-(8-quinolylsulfonyl)nipecotamide Melanocortin receptor 4 Homo sapiens >64585 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88588 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88588&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5210018 252660256 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192900 Cc1nnc(-c2cccc(Br)c2)c2cn(nc12)-c1cccc(Br)c1 InChI=1S/C18H12Br2N4/c1-11-17-16(10-24(23-17)15-7-3-6-14(20)9-15)18(22-21-11)12-4-2-5-13(19)8-12/h2-10H,1H3 AECFCCDRHPPLMX-UHFFFAOYSA-N 88589 cid_1214669::2,4-bis(3-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine::SMR000164076::MLS000544661::2,4-bis(3-bromophenyl)-7-methyl-2H-pyrazolo[3,4-d]pyridazine::2,4-bis(3-bromophenyl)-7-methyl-pyrazolo[3,4-d]pyridazine Melanocortin receptor 4 Homo sapiens >64596 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88589 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88589&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1214669 252660257 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192901 COc1ccc(OC)c(c1)C1C2C(=O)CCCC2=NC(C)=C1C(=O)Nc1nc2ccccc2s1 |c:19,22| InChI=1S/C26H25N3O4S/c1-14-22(25(31)29-26-28-17-7-4-5-10-21(17)34-26)23(24-18(27-14)8-6-9-19(24)30)16-13-15(32-2)11-12-20(16)33-3/h4-5,7,10-13,23-24H,6,8-9H2,1-3H3,(H,28,29,31) UTCLZJWUIKBCLI-UHFFFAOYSA-N 88590 MLS000543602::N-(1,3-benzothiazol-2-yl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxamide::N-(1,3-benzothiazol-2-yl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide::SMR000161040::cid_3761713::N-(1,3-benzothiazol-2-yl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide::N-(1,3-benzothiazol-2-yl)-4-(2,5-dimethoxyphenyl)-5-keto-2-methyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide Melanocortin receptor 4 Homo sapiens 12579 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88590 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88590&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899118 252660258 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192902 COc1ccc(OC)c(c1)N(C(C(=O)NC1CCCC1)c1cccs1)C(=O)C#C InChI=1S/C22H24N2O4S/c1-4-20(25)24(17-14-16(27-2)11-12-18(17)28-3)21(19-10-7-13-29-19)22(26)23-15-8-5-6-9-15/h1,7,10-15,21H,5-6,8-9H2,2-3H3,(H,23,26) XFZISNSMDWZRLJ-UHFFFAOYSA-N 63097 cid_3216694::SMR000173283::N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,5-dimethoxyphenyl)prop-2-ynamide::MLS000556132::N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,5-dimethoxyphenyl)-2-propynamide::Propynoic acid (cyclopentylcarbamoyl-thiophen-2-yl-methyl)-(2,5-dimethoxy-phenyl)-amide::N-[2-(cyclopentylamino)-2-oxidanylidene-1-thiophen-2-yl-ethyl]-N-(2,5-dimethoxyphenyl)prop-2-ynamide::N-[2-(cyclopentylamino)-2-keto-1-(2-thienyl)ethyl]-N-(2,5-dimethoxyphenyl)propiolamide Melanocortin receptor 4 Homo sapiens >64598 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=63097 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=63097&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3216694 252642211 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192903 COc1ccc(cc1OC)N(C(C(=O)NC1CCCC1)c1cccs1)C(=O)C#C InChI=1S/C22H24N2O4S/c1-4-20(25)24(16-11-12-17(27-2)18(14-16)28-3)21(19-10-7-13-29-19)22(26)23-15-8-5-6-9-15/h1,7,10-15,21H,5-6,8-9H2,2-3H3,(H,23,26) XSVGNUQFHJPDRN-UHFFFAOYSA-N 67917 N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(3,4-dimethoxyphenyl)prop-2-ynamide;hydrochloride::MLS000555378::cid_11958738::N-[2-(cyclopentylamino)-2-oxidanylidene-1-thiophen-2-yl-ethyl]-N-(3,4-dimethoxyphenyl)prop-2-ynamide;hydrochloride::N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(3,4-dimethoxyphenyl)-2-propynamide;hydrochloride::Propynoic acid (cyclopentylcarbamoyl-thiophen-2-yl-methyl)-(3,4-dimethoxy-phenyl)-amide::SMR000173282::N-[2-(cyclopentylamino)-2-keto-1-(2-thienyl)ethyl]-N-(3,4-dimethoxyphenyl)propiolamide;hydrochloride Melanocortin receptor 4 Homo sapiens 2515 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67917 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67917&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3216692 252646199 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192904 COc1ccc(cc1)C(=O)C(=C/c1ccco1)\N1C=CC=CC1=C(C#N)C#N |c:20,22,(15.5,1.39,;14.16,2.16,;12.83,1.39,;11.49,2.16,;10.16,1.39,;10.16,-.15,;11.49,-.92,;12.83,-.15,;8.83,-.92,;8.83,-2.46,;7.49,-.15,;6.16,-.92,;6.16,-2.46,;4.91,-3.36,;5.39,-4.83,;6.93,-4.83,;7.41,-3.36,;7.49,1.39,;8.83,2.16,;8.83,3.7,;7.49,4.47,;6.16,3.7,;6.16,2.16,;4.62,2.16,;3.85,3.5,;3.08,4.83,;3.85,.83,;3.08,-.51,)| InChI=1S/C22H15N3O3/c1-27-18-9-7-16(8-10-18)22(26)21(13-19-5-4-12-28-19)25-11-3-2-6-20(25)17(14-23)15-24/h2-13H,1H3 JFKFQMKJUPIWAU-UHFFFAOYSA-N 54800 2-[1-[(E)-1-(2-furanyl)-3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]-2-pyridinylidene]propanedinitrile::SMR000176548::2-{1-[2-Furan-2-yl-1-(4-methoxy-benzoyl)-vinyl]-1H-pyridin-2-ylidene}-malononitrile::MLS000555673::2-[1-[(E)-1-(furan-2-yl)-3-(4-methoxyphenyl)-3-oxidanylidene-prop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile::2-[1-[(E)-1-(furan-2-yl)-3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile::cid_5761997::2-[1-[(E)-2-(2-furyl)-1-p-anisoyl-vinyl]-2-pyridylidene]malononitrile Melanocortin receptor 4 Homo sapiens >64583 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54800 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54800&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5761997 252634817 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192905 CCCc1nc(SCC(=O)Nc2nc3CCCCc3s2)c2ccccc2n1 InChI=1S/C20H22N4OS2/c1-2-7-17-21-14-9-4-3-8-13(14)19(23-17)26-12-18(25)24-20-22-15-10-5-6-11-16(15)27-20/h3-4,8-9H,2,5-7,10-12H2,1H3,(H,22,24,25) WKKOBEPTXJLDBD-UHFFFAOYSA-N 88591 MLS000556665::2-[(2-propyl-4-quinazolinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide::cid_1442634::SMR000173430::2-(2-Propyl-quinazolin-4-ylsulfanyl)-N-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide::2-(2-propylquinazolin-4-yl)sulfanyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethanamide::2-(2-propylquinazolin-4-yl)sulfanyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide::2-[(2-propylquinazolin-4-yl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide Melanocortin receptor 4 Homo sapiens >64583 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88591 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88591&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1442634 252660259 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192906 COc1cc(cc(OC)c1OC)-c1nc2ccc3ccccc3c2c2CCCc12 InChI=1S/C25H23NO3/c1-27-21-13-16(14-22(28-2)25(21)29-3)24-19-10-6-9-18(19)23-17-8-5-4-7-15(17)11-12-20(23)26-24/h4-5,7-8,11-14H,6,9-10H2,1-3H3 YKJAZHKMXQRODM-UHFFFAOYSA-N 88592 4-(3,4,5-Trimethoxy-phenyl)-2,3-dihydro-1H-benzo[f]cyclopenta[c]quinoline::SMR000175083::MLS000561697::cid_1050448 Melanocortin receptor 4 Homo sapiens 43148 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88592 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88592&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1050448 242053815 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192907 CCOC(=O)c1cnc2ccc(C)cc2c1Nc1ccc(cc1)N1CCOCC1 InChI=1S/C23H25N3O3/c1-3-29-23(27)20-15-24-21-9-4-16(2)14-19(21)22(20)25-17-5-7-18(8-6-17)26-10-12-28-13-11-26/h4-9,14-15H,3,10-13H2,1-2H3,(H,24,25) OTKPJORJFHKENB-UHFFFAOYSA-N 41085 MLS000575705::6-methyl-4-[4-(4-morpholinyl)anilino]-3-quinolinecarboxylic acid ethyl ester::ethyl 6-methyl-4-(4-morpholin-4-ylanilino)quinoline-3-carboxylate::SMR000196739::ethyl 6-methyl-4-{[4-(4-morpholinyl)phenyl]amino}-3-quinolinecarboxylate::ethyl 6-methyl-4-[(4-morpholin-4-ylphenyl)amino]quinoline-3-carboxylate::cid_1190554::6-methyl-4-(4-morpholinoanilino)quinoline-3-carboxylic acid ethyl ester Melanocortin receptor 4 Homo sapiens 19035 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41085 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41085&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1190554 252621862 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192908 [O-][N+](=O)c1cc(ccc1Sc1nc2ccccc2s1)S(=O)(=O)C(F)(F)F InChI=1S/C14H7F3N2O4S3/c15-14(16,17)26(22,23)8-5-6-12(10(7-8)19(20)21)25-13-18-9-3-1-2-4-11(9)24-13/h1-7H JFMKAJVOAZEPMX-UHFFFAOYSA-N 65129 2-[[2-nitro-4-(trifluoromethylsulfonyl)phenyl]thio]-1,3-benzothiazole::2-({2-nitro-4-[(trifluoromethyl)sulfonyl]phenyl}thio)-1,3-benzothiazole::MLS000573311::cid_2277493::2-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]sulfanyl-1,3-benzothiazole::SMR000194813::2-[(2-nitro-4-triflyl-phenyl)thio]-1,3-benzothiazole Melanocortin receptor 4 Homo sapiens >2391 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65129 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65129&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2277493 252643932 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192909 CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2cccs2)C(=O)C1 InChI=1S/C21H26O4S/c1-20(2)8-12(22)17(13(23)9-20)19(16-6-5-7-26-16)18-14(24)10-21(3,4)11-15(18)25/h5-7,17-19H,8-11H2,1-4H3 ZZIMEKBRWHMUEA-UHFFFAOYSA-N 88593 2-[(4,4-dimethyl-2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)-thiophen-2-yl-methyl]-5,5-dimethyl-cyclohexane-1,3-dione::cid_3573522::2-[(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)-thiophen-2-ylmethyl]-5,5-dimethylcyclohexane-1,3-dione::2-[(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)(2-thienyl)methyl]-5,5-dimethyl-1,3-cyclohexanedione::MLS000572484::2-[(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexenyl)-thiophen-2-ylmethyl]-5,5-dimethylcyclohexane-1,3-dione::SMR000194442::2-[(2-hydroxy-6-keto-4,4-dimethyl-cyclohexen-1-yl)-(2-thienyl)methyl]-5,5-dimethyl-cyclohexane-1,3-quinone Melanocortin receptor 4 Homo sapiens 29915 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88593 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88593&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2838222 252660260 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192910 CCc1ccc(OCC(=O)NC(NC(=S)Nc2ccccc2OC)C(Cl)(Cl)Cl)cc1 InChI=1S/C20H22Cl3N3O3S/c1-3-13-8-10-14(11-9-13)29-12-17(27)25-18(20(21,22)23)26-19(30)24-15-6-4-5-7-16(15)28-2/h4-11,18H,3,12H2,1-2H3,(H,25,27)(H2,24,26,30) RRSRBHCVBHVKSV-UHFFFAOYSA-N 88594 2-(4-ethylphenoxy)-N-[2,2,2-trichloro-1-[(2-methoxyphenyl)carbamothioylamino]ethyl]acetamide::2-(4-ethylphenoxy)-N-[2,2,2-tris(chloranyl)-1-[(2-methoxyphenyl)carbamothioylamino]ethyl]ethanamide::MLS000573507::SMR000195010::cid_2898120::2-(4-ethylphenoxy)-N-[2,2,2-trichloro-1-[[(2-methoxyanilino)-sulfanylidenemethyl]amino]ethyl]acetamide::2-(4-ethylphenoxy)-N-[2,2,2-trichloro-1-({[(2-methoxyphenyl)amino]carbonothioyl}amino)ethyl]acetamide::2-(4-ethylphenoxy)-N-[2,2,2-trichloro-1-[(2-methoxyphenyl)thiocarbamoylamino]ethyl]acetamide Melanocortin receptor 4 Homo sapiens >64579 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88594 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88594&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2898120 252660261 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192911 Clc1cc(Cl)cc(c1)-n1c(n[nH]c1=S)-c1ccc2ccccc2n1 InChI=1S/C17H10Cl2N4S/c18-11-7-12(19)9-13(8-11)23-16(21-22-17(23)24)15-6-5-10-3-1-2-4-14(10)20-15/h1-9H,(H,22,24) FEVQYSDSPSYMMY-UHFFFAOYSA-N 88595 4-[3,5-bis(chloranyl)phenyl]-3-quinolin-2-yl-1H-1,2,4-triazole-5-thione::4-(3,5-dichlorophenyl)-3-(2-quinolinyl)-1H-1,2,4-triazole-5-thione::MLS000582745::4-(3,5-dichlorophenyl)-3-quinolin-2-yl-1H-1,2,4-triazole-5-thione::SMR000201448::4-(3,5-dichlorophenyl)-5-(2-quinolinyl)-4H-1,2,4-triazole-3-thiol::cid_1256628::4-(3,5-dichlorophenyl)-3-(2-quinolyl)-1H-1,2,4-triazole-5-thione Melanocortin receptor 4 Homo sapiens >64578 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88595 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88595&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1256628 252660262 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192912 Cc1ccc(cc1)-n1nc2ccc(NC(=S)NC(=O)C=Cc3ccco3)cc2n1 |w:19.19| InChI=1S/C21H17N5O2S/c1-14-4-7-16(8-5-14)26-24-18-10-6-15(13-19(18)25-26)22-21(29)23-20(27)11-9-17-3-2-12-28-17/h2-13H,1H3,(H2,22,23,27,29) PIACARLBZQHJRZ-UHFFFAOYSA-N 88596 MLS000573895::SMR000195482::cid_1343565::(E)-3-(2-furanyl)-N-[[[2-(4-methylphenyl)-5-benzotriazolyl]amino]-sulfanylidenemethyl]-2-propenamide::(E)-3-(furan-2-yl)-N-[[2-(4-methylphenyl)benzotriazol-5-yl]carbamothioyl]prop-2-enamide::3-(2-furyl)-N-({[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]amino}carbonothioyl)acrylamide::(E)-3-(2-furyl)-N-[[2-(p-tolyl)benzotriazol-5-yl]thiocarbamoyl]acrylamide Melanocortin receptor 4 Homo sapiens 55558 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88596 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88596&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1343565 252660263 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192913 COc1cccc2[nH]c3c(Cl)ncnc3c12 InChI=1S/C11H8ClN3O/c1-16-7-4-2-3-6-8(7)9-10(15-6)11(12)14-5-13-9/h2-5,15H,1H3 AZGSGDAPZUDANU-UHFFFAOYSA-N 88597 SMR000220843::MLS000331382::4-chloranyl-9-methoxy-5H-pyrimido[5,4-b]indole::cid_5423078::4-chloro-9-methoxy-5H-pyrimido[5,4-b]indole::4-chloro-9-methoxy-5H-pyrimid[5,4-b]indole Melanocortin receptor 4 Homo sapiens >64592 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88597 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88597&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5423078 252660264 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192914 [O-][N+](=O)c1cc(ccc1Br)C(=O)Oc1ccccc1C(=O)Nc1ccccc1 InChI=1S/C20H13BrN2O5/c21-16-11-10-13(12-17(16)23(26)27)20(25)28-18-9-5-4-8-15(18)19(24)22-14-6-2-1-3-7-14/h1-12H,(H,22,24) ONLMRIYNWGCRLQ-UHFFFAOYSA-N 88598 MLS000574735::2-(anilinocarbonyl)phenyl 4-bromo-3-nitrobenzoate::cid_1332281::[2-(phenylcarbamoyl)phenyl] 4-bromanyl-3-nitro-benzoate::[2-(phenylcarbamoyl)phenyl] 4-bromo-3-nitrobenzoate::SMR000196165::4-bromo-3-nitrobenzoic acid [2-[anilino(oxo)methyl]phenyl] ester::4-bromo-3-nitro-benzoic acid [2-(phenylcarbamoyl)phenyl] ester Melanocortin receptor 4 Homo sapiens >64574 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88598 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88598&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1332281 252660265 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192915 Cc1nn(c(Cl)c1CN(C(=O)CCl)c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C19H16Cl3N3O/c1-13-17(19(22)25(23-13)16-5-3-2-4-6-16)12-24(18(26)11-20)15-9-7-14(21)8-10-15/h2-10H,11-12H2,1H3 SEBZYCZOQDPQHF-UHFFFAOYSA-N 56561 cid_1124686::MLS000552974::2-Chloro-N-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-ylmethyl)-N-(4-chloro-phenyl)-acetamide::2-chloranyl-N-[(5-chloranyl-3-methyl-1-phenyl-pyrazol-4-yl)methyl]-N-(4-chlorophenyl)ethanamide::2-chloro-N-[(5-chloro-3-methyl-1-phenyl-4-pyrazolyl)methyl]-N-(4-chlorophenyl)acetamide::SMR000176967::2-chloro-N-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methyl]-N-(4-chlorophenyl)acetamide::2-chloro-N-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methyl]-N-(4-chlorophenyl)acetamide Melanocortin receptor 4 Homo sapiens >64570 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=56561 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=56561&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1124686 252636522 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192916 CCOC(=O)c1cnc2ccc(OCC)cc2c1NCc1ccccc1 InChI=1S/C21H22N2O3/c1-3-25-16-10-11-19-17(12-16)20(18(14-22-19)21(24)26-4-2)23-13-15-8-6-5-7-9-15/h5-12,14H,3-4,13H2,1-2H3,(H,22,23) ZPGNLZJITSLBES-UHFFFAOYSA-N 88599 MLS000585217::ethyl 6-ethoxy-4-[(phenylmethyl)amino]quinoline-3-carboxylate::ethyl 4-(benzylamino)-6-ethoxyquinoline-3-carboxylate::SMR000203980::cid_1187196::6-ethoxy-4-[(phenylmethyl)amino]-3-quinolinecarboxylic acid ethyl ester::4-(benzylamino)-6-ethoxy-quinoline-3-carboxylic acid ethyl ester Melanocortin receptor 4 Homo sapiens >64589 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88599 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88599&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1187196 252660266 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192917 Cc1ccc(Nc2nc(N=NCc3c[nH]c4ccccc34)nc(n2)N2CCOCC2)cc1 |w:9.8| InChI=1S/C23H24N8O/c1-16-6-8-18(9-7-16)26-21-27-22(29-23(28-21)31-10-12-32-13-11-31)30-25-15-17-14-24-20-5-3-2-4-19(17)20/h2-9,14,24H,10-13,15H2,1H3,(H,26,27,28,29) PBMNRUXXANZCIL-UHFFFAOYSA-N 88600 SMR000204347::4-[2-[(Z)-indol-3-ylidenemethyl]hydrazinyl]-N-(4-methylphenyl)-6-morpholin-4-yl-1,3,5-triazin-2-amine::cid_6529816::1H-indole-3-carbaldehyde {4-[(4-methylphenyl)amino]-6-morpholin-4-yl-1,3,5-triazin-2-yl}hydrazone::4-[[(Z)-3-indolylidenemethyl]hydrazo]-N-(4-methylphenyl)-6-(4-morpholinyl)-1,3,5-triazin-2-amine::MLS000585784::[4-[N'-[(Z)-indol-3-ylidenemethyl]hydrazino]-6-morpholino-s-triazin-2-yl]-(p-tolyl)amine Melanocortin receptor 4 Homo sapiens >64562 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88600 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88600&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899119 252660267 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192918 [O-][N+](=O)c1cccc2C(=O)N(C(=O)c12)c1ccccc1 InChI=1S/C14H8N2O4/c17-13-10-7-4-8-11(16(19)20)12(10)14(18)15(13)9-5-2-1-3-6-9/h1-8H OMOHDUGKQSTKSR-UHFFFAOYSA-N 50088682 CHEMBL11614::cid_272783::4-Nitro-2-phenyl-isoindole-1,3-dione Melanocortin receptor 4 Homo sapiens >64632 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088682 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088682&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 272783 103987559 CHEMBL11614 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192919 CCOC(=O)c1cnc2ccc(OCC)cc2c1N(C)Cc1ccccc1 InChI=1S/C22H24N2O3/c1-4-26-17-11-12-20-18(13-17)21(19(14-23-20)22(25)27-5-2)24(3)15-16-9-7-6-8-10-16/h6-14H,4-5,15H2,1-3H3 FTGFLMLLQAIYGW-UHFFFAOYSA-N 88601 ethyl 4-[benzyl(methyl)amino]-6-ethoxyquinoline-3-carboxylate::MLS000586213::cid_6621000::SMR000204576::ethyl 6-ethoxy-4-[methyl-(phenylmethyl)amino]quinoline-3-carboxylate::6-ethoxy-4-[methyl-(phenylmethyl)amino]-3-quinolinecarboxylic acid ethyl ester::4-[benzyl(methyl)amino]-6-ethoxy-quinoline-3-carboxylic acid ethyl ester Melanocortin receptor 4 Homo sapiens >64581 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88601 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88601&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 6621000 252660268 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192920 [H]C12CCC(OC(=O)Nc3ccccc3)C([H])(CCC1OC(=O)Nc1ccccc1)C2 |TLB:20:19:30:4.2.3,THB:5:4:30:19.17.18| 88602 N-phenylcarbamic acid [2-[anilino(oxo)methoxy]-6-bicyclo[3.3.1]nonanyl] ester::MLS000589614::[2-(phenylcarbamoyloxy)-6-bicyclo[3.3.1]nonanyl] N-phenylcarbamate::SMR000212952::cid_3617229::N-phenylcarbamic acid [2-(phenylcarbamoyloxy)-6-bicyclo[3.3.1]nonanyl] ester Melanocortin receptor 4 Homo sapiens 7464 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88602 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88602&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3617229 252660269 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192921 COc1ccc(CN=Nc2cc(C)nc(NS(=O)(=O)c3ccc(C)cc3)n2)cc1 |w:8.8| InChI=1S/C20H21N5O3S/c1-14-4-10-18(11-5-14)29(26,27)25-20-22-15(2)12-19(23-20)24-21-13-16-6-8-17(28-3)9-7-16/h4-12H,13H2,1-3H3,(H,22,23,25) YMCFCDBOPFPJOG-UHFFFAOYSA-N 88603 N-(4-{N'-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-hydrazino}-6-methyl-pyrimidin-2-yl)-4-methyl-benzenesulfonamide::N-[4-[(2E)-2-[(4-methoxyphenyl)methylidene]hydrazinyl]-6-methyl-2-pyrimidinyl]-4-methylbenzenesulfonamide::SMR000211182::N-[4-[(2E)-2-[(4-methoxyphenyl)methylidene]hydrazinyl]-6-methyl-pyrimidin-2-yl]-4-methyl-benzenesulfonamide::MLS000587209::N-[4-[(2E)-2-[(4-methoxyphenyl)methylidene]hydrazinyl]-6-methylpyrimidin-2-yl]-4-methylbenzenesulfonamide::cid_9626553::4-methyl-N-[4-methyl-6-[(N'E)-N'-p-anisylidenehydrazino]pyrimidin-2-yl]benzenesulfonamide Melanocortin receptor 4 Homo sapiens >64589 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88603 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88603&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899120 252660270 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192922 CCOC(=O)c1ccc2ncc(C(=O)OCC)c(Nc3ccc(cc3)N3CCOCC3)c2c1 InChI=1S/C25H27N3O5/c1-3-32-24(29)17-5-10-22-20(15-17)23(21(16-26-22)25(30)33-4-2)27-18-6-8-19(9-7-18)28-11-13-31-14-12-28/h5-10,15-16H,3-4,11-14H2,1-2H3,(H,26,27) XOKPVAFBMLWNSV-UHFFFAOYSA-N 68992 diethyl 4-[(4-morpholin-4-ylphenyl)amino]quinoline-3,6-dicarboxylate::cid_1190175::MLS000590451::4-(4-Morpholin-4-yl-phenylamino)-quinoline-3,6-dicarboxylic acid diethyl ester::diethyl 4-(4-morpholin-4-ylanilino)quinoline-3,6-dicarboxylate::SMR000217520::4-[4-(4-morpholinyl)anilino]quinoline-3,6-dicarboxylic acid diethyl ester::4-(4-morpholinoanilino)quinoline-3,6-dicarboxylic acid diethyl ester Melanocortin receptor 4 Homo sapiens 8672 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68992 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68992&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1190175 252647164 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192923 CCOC(=O)c1c(NC(=O)COc2cccc3C(=O)N(C)CCc23)sc2CCCc12 InChI=1S/C22H24N2O5S/c1-3-28-22(27)19-15-7-5-9-17(15)30-20(19)23-18(25)12-29-16-8-4-6-14-13(16)10-11-24(2)21(14)26/h4,6,8H,3,5,7,9-12H2,1-2H3,(H,23,25) MZHXDNQYKWQVBK-UHFFFAOYSA-N 88604 ethyl 2-[[2-[(2-methyl-1-oxo-3,4-dihydroisoquinolin-5-yl)oxy]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate::SMR000236099::MLS000723118::cid_4407190::2-[[2-[(2-methyl-1-oxo-3,4-dihydroisoquinolin-5-yl)oxy]-1-oxoethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester::ethyl 2-[2-[(2-methyl-1-oxidanylidene-3,4-dihydroisoquinolin-5-yl)oxy]ethanoylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate::2-[[2-[(1-keto-2-methyl-3,4-dihydroisoquinolin-5-yl)oxy]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester Melanocortin receptor 4 Homo sapiens >64591 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88604 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88604&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4407190 252660271 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192924 NS(=O)(=O)c1ccc2n(CC=C)\c(=N\C(=O)c3sc4ccccc4c3Cl)sc2c1 InChI=1S/C19H14ClN3O3S3/c1-2-9-23-13-8-7-11(29(21,25)26)10-15(13)28-19(23)22-18(24)17-16(20)12-5-3-4-6-14(12)27-17/h2-8,10H,1,9H2,(H2,21,25,26) CCJHUABELYJYIC-UHFFFAOYSA-N 82737 3-chloranyl-N-(3-prop-2-enyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)-1-benzothiophene-2-carboxamide::MLS000697139::cid_4113455::SMR000237870::3-chloro-N-(3-prop-2-enyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)-1-benzothiophene-2-carboxamide::N-(3-allyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)-3-chloro-benzothiophene-2-carboxamide Melanocortin receptor 4 Homo sapiens 30690 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82737 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82737&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4113455 252657941 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192925 CC(Sc1nncs1)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C19H16N4OS3/c1-11-3-8-15-16(9-11)27-18(22-15)13-4-6-14(7-5-13)21-17(24)12(2)26-19-23-20-10-25-19/h3-10,12H,1-2H3,(H,21,24) RCHCVYAJKNGFQP-UHFFFAOYSA-N 88605 MLS000335805::N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylsulfanyl)propanamide::SMR000253559::N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylthio)propanamide::cid_4881126::N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylthio)propionamide Melanocortin receptor 4 Homo sapiens >64592 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88605 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88605&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4881126 252660272 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192926 Cc1ccc(NC(=O)c2cc(ccc2N2CCOCC2)N2C(=O)C=CC2=O)cc1Cl |c:25| InChI=1S/C22H20ClN3O4/c1-14-2-3-15(12-18(14)23)24-22(29)17-13-16(26-20(27)6-7-21(26)28)4-5-19(17)25-8-10-30-11-9-25/h2-7,12-13H,8-11H2,1H3,(H,24,29) MFLBKFTVOYEZKX-UHFFFAOYSA-N 57650 N-(3-chloro-4-methylphenyl)-5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-(4-morpholinyl)benzamide::MLS000678894::cid_1335691::5-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(3-chloranyl-4-methyl-phenyl)-2-morpholin-4-yl-benzamide::N-(3-chloro-4-methylphenyl)-5-(2,5-dioxopyrrol-1-yl)-2-morpholin-4-ylbenzamide::N-(3-chloro-4-methylphenyl)-5-(2,5-dioxo-1-pyrrolyl)-2-(4-morpholinyl)benzamide::SMR000269962::N-(3-chloro-4-methyl-phenyl)-5-maleimido-2-morpholino-benzamide Melanocortin receptor 4 Homo sapiens 8430 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57650 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57650&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1335691 252637573 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192927 CC(C)N(c1ccccc1)c1ccc(NC(=O)COC(=O)CCN2C(=O)c3cccc(c3C2=O)[N+]([O-])=O)cc1 InChI=1S/C28H26N4O7/c1-18(2)31(20-7-4-3-5-8-20)21-13-11-19(12-14-21)29-24(33)17-39-25(34)15-16-30-27(35)22-9-6-10-23(32(37)38)26(22)28(30)36/h3-14,18H,15-17H2,1-2H3,(H,29,33) NKFZBEXEQQQAGX-UHFFFAOYSA-N 88606 cid_2370680::MLS000375182::3-(4-nitro-1,3-dioxo-2-isoindolyl)propanoic acid [2-oxo-2-[4-(N-propan-2-ylanilino)anilino]ethyl] ester::[2-oxidanylidene-2-[[4-[phenyl(propan-2-yl)amino]phenyl]amino]ethyl] 3-[4-nitro-1,3-bis(oxidanylidene)isoindol-2-yl]propanoate::[2-oxo-2-[4-(N-propan-2-ylanilino)anilino]ethyl] 3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoate::SMR000254435::3-(1,3-diketo-4-nitro-isoindolin-2-yl)propionic acid [2-[4-(N-isopropylanilino)anilino]-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64577 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88606 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88606&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2370680 252660273 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192928 CN(c1ccc(OCC(=O)OCC(=O)Nc2ccc(Br)cc2)cc1)S(=O)(=O)c1cccs1 InChI=1S/C21H19BrN2O6S2/c1-24(32(27,28)21-3-2-12-31-21)17-8-10-18(11-9-17)29-14-20(26)30-13-19(25)23-16-6-4-15(22)5-7-16/h2-12H,13-14H2,1H3,(H,23,25) AOGPKUWIJLMYCC-UHFFFAOYSA-N 88607 MLS000416520::[2-(4-bromoanilino)-2-oxoethyl] 2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]acetate::2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]acetic acid [2-(4-bromoanilino)-2-oxoethyl] ester::SMR000243419::cid_2577649::[2-[(4-bromophenyl)amino]-2-oxidanylidene-ethyl] 2-[4-[methyl(thiophen-2-ylsulfonyl)amino]phenoxy]ethanoate::2-[4-[methyl(2-thienylsulfonyl)amino]phenoxy]acetic acid [2-(4-bromoanilino)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64583 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88607 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88607&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2577649 252660274 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192929 Cc1ccc(C)c(NC(=O)COC(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)c1 InChI=1S/C25H19NO5/c1-14-10-11-15(2)20(12-14)26-21(27)13-31-25(30)19-9-5-8-18-22(19)24(29)17-7-4-3-6-16(17)23(18)28/h3-12H,13H2,1-2H3,(H,26,27) OMPCMBHIBKZMTM-UHFFFAOYSA-N 88608 [2-(2,5-dimethylanilino)-2-oxoethyl] 9,10-dioxoanthracene-1-carboxylate::MLS000390666::cid_3503149::SMR000259705::9,10-dioxo-1-anthracenecarboxylic acid [2-(2,5-dimethylanilino)-2-oxoethyl] ester::[2-[(2,5-dimethylphenyl)amino]-2-oxidanylidene-ethyl] 9,10-bis(oxidanylidene)anthracene-1-carboxylate::9,10-diketoanthracene-1-carboxylic acid [2-(2,5-dimethylanilino)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64592 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88608 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88608&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3503149 252660275 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192930 COc1cc2c(cc1NC(=O)COC(=O)CNS(=O)(=O)c1ccc(C)cc1)oc1ccccc21 InChI=1S/C24H22N2O7S/c1-15-7-9-16(10-8-15)34(29,30)25-13-24(28)32-14-23(27)26-19-12-21-18(11-22(19)31-2)17-5-3-4-6-20(17)33-21/h3-12,25H,13-14H2,1-2H3,(H,26,27) OMMSTSOZGIYTSL-UHFFFAOYSA-N 88609 SMR000243858::MLS000393389::cid_2078942::[2-[(2-methoxydibenzofuran-3-yl)amino]-2-oxoethyl] 2-[(4-methylphenyl)sulfonylamino]acetate::2-[(4-methylphenyl)sulfonylamino]acetic acid [2-[(2-methoxy-3-dibenzofuranyl)amino]-2-oxoethyl] ester::[2-[(2-methoxydibenzofuran-3-yl)amino]-2-oxidanylidene-ethyl] 2-[(4-methylphenyl)sulfonylamino]ethanoate::2-(tosylamino)acetic acid [2-keto-2-[(2-methoxydibenzofuran-3-yl)amino]ethyl] ester Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88609 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88609&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2078942 252660276 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192931 COC(=O)c1c2CCCCCc2sc1NC(=O)COC(=O)c1ccc(Cl)cc1[N+]([O-])=O InChI=1S/C20H19ClN2O7S/c1-29-20(26)17-13-5-3-2-4-6-15(13)31-18(17)22-16(24)10-30-19(25)12-8-7-11(21)9-14(12)23(27)28/h7-9H,2-6,10H2,1H3,(H,22,24) KZAAOZALALIPEY-UHFFFAOYSA-N 88610 methyl 2-[2-(4-chloranyl-2-nitro-phenyl)carbonyloxyethanoylamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate::2-[[2-[(4-chloro-2-nitrophenyl)-oxomethoxy]-1-oxoethyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid methyl ester::cid_2411726::SMR000264231::methyl 2-[[2-(4-chloro-2-nitrobenzoyl)oxyacetyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate::MLS000416448::2-[[2-(4-chloro-2-nitro-benzoyl)oxyacetyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid methyl ester Melanocortin receptor 4 Homo sapiens >64562 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88610 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88610&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2411726 252660277 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192932 Cc1nc2ccc(NC(=O)c3ccc(Cl)c(c3)[N+]([O-])=O)cc2s1 InChI=1S/C15H10ClN3O3S/c1-8-17-12-5-3-10(7-14(12)23-8)18-15(20)9-2-4-11(16)13(6-9)19(21)22/h2-7H,1H3,(H,18,20) DDKPJTSGMWLVTI-UHFFFAOYSA-N 88611 4-chloro-N-(2-methyl-1,3-benzothiazol-6-yl)-3-nitrobenzamide::MLS000390704::4-chloranyl-N-(2-methyl-1,3-benzothiazol-6-yl)-3-nitro-benzamide::cid_1203284::SMR000259742::4-chloro-N-(2-methyl-1,3-benzothiazol-6-yl)-3-nitro-benzamide Melanocortin receptor 4 Homo sapiens >64583 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88611 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88611&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1203284 252660278 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192933 CC1CCCN(C1)c1nc(nc2scc(-c3ccccc3)c12)-c1cccnc1 InChI=1S/C23H22N4S/c1-16-7-6-12-27(14-16)22-20-19(17-8-3-2-4-9-17)15-28-23(20)26-21(25-22)18-10-5-11-24-13-18/h2-5,8-11,13,15-16H,6-7,12,14H2,1H3 CIKJUBWQMFXUKK-UHFFFAOYSA-N 88612 4-(3-methylpiperidin-1-yl)-5-phenyl-2-pyridin-3-yl-thieno[2,3-d]pyrimidine::4-(3-methyl-1-piperidinyl)-5-phenyl-2-(3-pyridinyl)thieno[2,3-d]pyrimidine::SMR000261931::cid_4834494::4-(3-methylpiperidin-1-yl)-5-phenyl-2-pyridin-3-ylthieno[2,3-d]pyrimidine::MLS000394554::4-(3-methylpiperidino)-5-phenyl-2-(3-pyridyl)thieno[2,3-d]pyrimidine Melanocortin receptor 4 Homo sapiens >64595 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88612 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88612&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4834494 252660279 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192934 Cc1sc2nc(CN3CCOCC3)nc(Cl)c2c1C InChI=1S/C13H16ClN3OS/c1-8-9(2)19-13-11(8)12(14)15-10(16-13)7-17-3-5-18-6-4-17/h3-7H2,1-2H3 IFNLFJLUYQMTKG-UHFFFAOYSA-N 88613 4-[(4-chloranyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-2-yl)methyl]morpholine::4-[(4-chloro-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)methyl]morpholine::MLS000375403::4-[(4-chloro-5,6-dimethyl-2-thieno[2,3-d]pyrimidinyl)methyl]morpholine::SMR000254657::cid_2442208::4-[(4-chloro-5,6-dimethyl-thieno[2,3-d]pyrimidin-2-yl)methyl]morpholine Melanocortin receptor 4 Homo sapiens >64542 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88613 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88613&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2442208 252660280 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192935 COC(=O)c1sc(N)c(C(=O)OC)c1COC(=O)CNS(=O)(=O)c1ccc(C)c(C)c1 InChI=1S/C19H22N2O8S2/c1-10-5-6-12(7-11(10)2)31(25,26)21-8-14(22)29-9-13-15(18(23)27-3)17(20)30-16(13)19(24)28-4/h5-7,21H,8-9,20H2,1-4H3 VMCJSHQXHMQQPP-UHFFFAOYSA-N 88614 cid_2508583::5-amino-3-[[2-[(3,4-dimethylphenyl)sulfonylamino]-1-oxoethoxy]methyl]thiophene-2,4-dicarboxylic acid dimethyl ester::dimethyl 5-azanyl-3-[2-[(3,4-dimethylphenyl)sulfonylamino]ethanoyloxymethyl]thiophene-2,4-dicarboxylate::SMR000242829::MLS000394686::dimethyl 5-amino-3-[[2-[(3,4-dimethylphenyl)sulfonylamino]acetyl]oxymethyl]thiophene-2,4-dicarboxylate::5-amino-3-[[2-[(3,4-dimethylphenyl)sulfonylamino]acetyl]oxymethyl]thiophene-2,4-dicarboxylic acid dimethyl ester Melanocortin receptor 4 Homo sapiens >64565 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88614 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88614&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2508583 252660281 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192936 Brc1cccc(c1)S(=O)(=O)NCC(=O)OCC(=O)Nc1ccccc1Sc1ccccc1 InChI=1S/C22H19BrN2O5S2/c23-16-7-6-10-18(13-16)32(28,29)24-14-22(27)30-15-21(26)25-19-11-4-5-12-20(19)31-17-8-2-1-3-9-17/h1-13,24H,14-15H2,(H,25,26) CRTFGGJCMNRZKX-UHFFFAOYSA-N 88615 SMR000243616::2-[(3-bromophenyl)sulfonylamino]acetic acid [2-oxo-2-[2-(phenylthio)anilino]ethyl] ester::MLS000409205::cid_2575495::[2-oxidanylidene-2-[(2-phenylsulfanylphenyl)amino]ethyl] 2-[(3-bromophenyl)sulfonylamino]ethanoate::[2-oxo-2-(2-phenylsulfanylanilino)ethyl] 2-[(3-bromophenyl)sulfonylamino]acetate::2-[(3-bromophenyl)sulfonylamino]acetic acid [2-keto-2-[2-(phenylthio)anilino]ethyl] ester Melanocortin receptor 4 Homo sapiens 8422 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88615 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88615&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2575495 252660282 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192937 CCOC(=O)c1ccc(cc1)\N=c1/sc(cc(=O)n1-c1ccc(cc1)C(=O)OCC)C(=O)OC InChI=1S/C24H22N2O7S/c1-4-32-21(28)15-6-10-17(11-7-15)25-24-26(20(27)14-19(34-24)23(30)31-3)18-12-8-16(9-13-18)22(29)33-5-2/h6-14H,4-5H2,1-3H3 RORAQVXURFUIFD-UHFFFAOYSA-N 72345 methyl 3-(4-ethoxycarbonylphenyl)-2-(4-ethoxycarbonylphenyl)imino-4-oxo-1,3-thiazine-6-carboxylate::3-(4-ethoxycarbonylphenyl)-2-(4-ethoxycarbonylphenyl)imino-4-oxo-1,3-thiazine-6-carboxylic acid methyl ester::methyl (2Z)-3-[4-(ethoxycarbonyl)phenyl]-2-{[4-(ethoxycarbonyl)phenyl]imino}-4-oxo-3,4-dihydro-2H-1,3-thiazine-6-carboxylate::cid_1519059::SMR000208795::MLS000586865::methyl 3-(4-ethoxycarbonylphenyl)-2-(4-ethoxycarbonylphenyl)imino-4-oxidanylidene-1,3-thiazine-6-carboxylate::3-(4-carbethoxyphenyl)-2-(4-carbethoxyphenyl)imino-4-keto-1,3-thiazine-6-carboxylic acid methyl ester Melanocortin receptor 4 Homo sapiens >64573 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72345 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72345&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1519059 252649607 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192938 CCOc1ccc(Nc2nc(Cl)nc(n2)N2CCN(CC2)c2ccc(OC)cc2)cc1 InChI=1S/C22H25ClN6O2/c1-3-31-19-8-4-16(5-9-19)24-21-25-20(23)26-22(27-21)29-14-12-28(13-15-29)17-6-10-18(30-2)11-7-17/h4-11H,3,12-15H2,1-2H3,(H,24,25,26,27) UOAKYFGDTSZLLF-UHFFFAOYSA-N 88616 MLS000698645::N-{4-chloro-6-[4-(4-methoxyphenyl)-1-piperazinyl]-1,3,5-triazin-2-yl}-N-(4-ethoxyphenyl)amine::4-chloro-N-(4-ethoxyphenyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-amine::cid_3427699::4-chloro-N-(4-ethoxyphenyl)-6-[4-(4-methoxyphenyl)-1-piperazinyl]-1,3,5-triazin-2-amine::4-chloranyl-N-(4-ethoxyphenyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3,5-triazin-2-amine::SMR000225845::[4-chloro-6-[4-(4-methoxyphenyl)piperazino]-s-triazin-2-yl]-p-phenetyl-amine Melanocortin receptor 4 Homo sapiens >64584 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88616 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88616&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3427699 252660283 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192939 CC1CCN(CC1)c1nc(Cl)nc(Nc2ccc(cc2)[N+]([O-])=O)n1 InChI=1S/C15H17ClN6O2/c1-10-6-8-21(9-7-10)15-19-13(16)18-14(20-15)17-11-2-4-12(5-3-11)22(23)24/h2-5,10H,6-9H2,1H3,(H,17,18,19,20) VDSUOWSPZRTSKD-UHFFFAOYSA-N 88617 SMR000226220::4-chloranyl-6-(4-methylpiperidin-1-yl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine::4-chloro-6-(4-methylpiperidin-1-yl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine::cid_7801294::MLS000699254::2-chloro-4-{4-nitroanilino}-6-(4-methyl-1-piperidinyl)-1,3,5-triazine::4-chloro-6-(4-methyl-1-piperidinyl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine::[4-chloro-6-(4-methylpiperidino)-s-triazin-2-yl]-(4-nitrophenyl)amine Melanocortin receptor 4 Homo sapiens >64542 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88617 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88617&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 7801294 252660284 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192940 CN1CCC(CC1)Oc1ccccc1Sc1ccc(cc1)C(F)(F)F InChI=1S/C19H20F3NOS/c1-23-12-10-15(11-13-23)24-17-4-2-3-5-18(17)25-16-8-6-14(7-9-16)19(20,21)22/h2-9,15H,10-13H2,1H3 MPXWIWCJZHUHQR-UHFFFAOYSA-N 88618 cid_14400561::ethanedioic acid;1-methyl-4-[2-[4-(trifluoromethyl)phenyl]sulfanylphenoxy]piperidine::1-methyl-4-[2-[4-(trifluoromethyl)phenyl]sulfanylphenoxy]piperidine;oxalic acid::SMR000224863::1-methyl-4-piperidinyl 2-{[4-(trifluoromethyl)phenyl]sulfanyl}phenyl ether::MLS000703854::1-methyl-4-[2-[[4-(trifluoromethyl)phenyl]thio]phenoxy]piperidine;oxalic acid Melanocortin receptor 4 Homo sapiens >64581 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88618 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88618&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1044054 252660285 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192941 CC1CCN(CC1)c1nc(C)nc2sc(C(=O)Nc3ccccc3C(F)(F)F)c(C)c12 InChI=1S/C22H23F3N4OS/c1-12-8-10-29(11-9-12)19-17-13(2)18(31-21(17)27-14(3)26-19)20(30)28-16-7-5-4-6-15(16)22(23,24)25/h4-7,12H,8-11H2,1-3H3,(H,28,30) BKBIFNJLMCCFLF-UHFFFAOYSA-N 57757 SMR000312025::2,5-dimethyl-4-(4-methylpiperidin-1-yl)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide::cid_4137233::2,5-dimethyl-4-(4-methyl-1-piperidinyl)-N-[2-(trifluoromethyl)phenyl]-6-thieno[2,3-d]pyrimidinecarboxamide::MLS000682668::2,5-dimethyl-4-(4-methylpiperidino)-N-[2-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide Melanocortin receptor 4 Homo sapiens >64573 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57757 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57757&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4137233 252637677 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192942 CCOC(=O)N1CCN(CCC(=O)c2ccc(OC)cc2)CC1 InChI=1S/C17H24N2O4/c1-3-23-17(21)19-12-10-18(11-13-19)9-8-16(20)14-4-6-15(22-2)7-5-14/h4-7H,3,8-13H2,1-2H3 XRCHIRNQJCHUPV-UHFFFAOYSA-N 88619 MLS000727731::SMR000306428::ethyl 4-[3-(4-methoxyphenyl)-3-oxopropyl]piperazine-1-carboxylate;hydrochloride::ethyl 4-[3-(4-methoxyphenyl)-3-oxidanylidene-propyl]piperazine-1-carboxylate;hydrochloride::4-[3-(4-methoxyphenyl)-3-oxopropyl]-1-piperazinecarboxylic acid ethyl ester;hydrochloride::cid_16188016::4-[3-keto-3-(4-methoxyphenyl)propyl]piperazine-1-carboxylic acid ethyl ester;hydrochloride Melanocortin receptor 4 Homo sapiens >64541 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88619 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88619&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5045937 252660286 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192943 [#6]C1([#6])[#8]-[#6](=O)\[#6](=[#6]/c2ccc(o2)-c2ccc(cc2)S([#7])(=O)=O)-[#6](=O)-[#8]1 InChI=1S/C17H6NO7S/c1-17(2)24-15(19)13(16(20)25-17)9-11-5-8-14(23-11)10-3-6-12(7-4-10)26(18,21)22/h3-8H NDHYBKAKHZCFFJ-UHFFFAOYSA-N 47770 SMR000273939::MLS000703574::cid_1154580::4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-2-furanyl]benzenesulfonamide::4-[5-[[2,2-dimethyl-4,6-bis(oxidanylidene)-1,3-dioxan-5-ylidene]methyl]furan-2-yl]benzenesulfonamide::4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]furan-2-yl]benzenesulfonamide::4-[5-[(4,6-diketo-2,2-dimethyl-1,3-dioxan-5-ylidene)methyl]-2-furyl]benzenesulfonamide Melanocortin receptor 4 Homo sapiens >64579 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47770 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47770&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1154580 252628071 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192944 Oc1ccc(O)n1-c1ccc(cc1)C(=O)Nc1ccccc1-c1nc2ccccc2[nH]1 InChI=1S/C24H18N4O3/c29-21-13-14-22(30)28(21)16-11-9-15(10-12-16)24(31)27-18-6-2-1-5-17(18)23-25-19-7-3-4-8-20(19)26-23/h1-14,29-30H,(H,25,26)(H,27,31) LBUXTMSAHZUNCP-UHFFFAOYSA-N 88620 N-[2-(1H-benzimidazol-2-yl)phenyl]-4-(2,5-dioxo-1-pyrrolidinyl)benzamide::cid_1548765::MLS000391959::SMR000260992::N-[2-(1H-benzimidazol-2-yl)phenyl]-4-(2,5-dioxopyrrolidin-1-yl)benzamide::N-[2-(1H-benzimidazol-2-yl)phenyl]-4-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]benzamide::N-[2-(1H-benzimidazol-2-yl)phenyl]-4-succinimido-benzamide Melanocortin receptor 4 Homo sapiens >21522 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88620 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88620&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91899121 252660287 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192945 COC(=O)C(CC(C)C)NC(=O)\C=C\c1ccc(Cl)cc1 InChI=1S/C16H20ClNO3/c1-11(2)10-14(16(20)21-3)18-15(19)9-6-12-4-7-13(17)8-5-12/h4-9,11,14H,10H2,1-3H3,(H,18,19) UHZDMUCWAYRRHW-UHFFFAOYSA-N 88621 2-[[(E)-3-(4-chlorophenyl)-1-oxoprop-2-enyl]amino]-4-methylpentanoic acid methyl ester::MLS000663882::methyl 2-[[(E)-3-(4-chlorophenyl)prop-2-enoyl]amino]-4-methylpentanoate::SMR000292385::cid_5738090::methyl 2-[[(E)-3-(4-chlorophenyl)prop-2-enoyl]amino]-4-methyl-pentanoate::methyl N-[3-(4-chlorophenyl)acryloyl]leucinate::2-[[(E)-3-(4-chlorophenyl)acryloyl]amino]-4-methyl-valeric acid methyl ester Melanocortin receptor 4 Homo sapiens >64608 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88621 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88621&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5738090 252660288 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192946 Cc1ccc(NC(=O)c2cc(ccc2N2CCOCC2)N2C(=O)C=CC2=O)cc1 |c:25| InChI=1S/C22H21N3O4/c1-15-2-4-16(5-3-15)23-22(28)18-14-17(25-20(26)8-9-21(25)27)6-7-19(18)24-10-12-29-13-11-24/h2-9,14H,10-13H2,1H3,(H,23,28) QKXCOBBZMYPLCG-UHFFFAOYSA-N 54813 MLS000708115::5-(2,5-dioxo-1-pyrrolyl)-N-(4-methylphenyl)-2-(4-morpholinyl)benzamide::SMR000287582::cid_1080132::5-(2,5-dioxopyrrol-1-yl)-N-(4-methylphenyl)-2-morpholin-4-ylbenzamide::5-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(4-methylphenyl)-2-morpholin-4-yl-benzamide::5-maleimido-2-morpholino-N-(p-tolyl)benzamide Melanocortin receptor 4 Homo sapiens 11907 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54813 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54813&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1080132 252634830 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192947 Oc1ccc(F)cc1C(=O)c1cnn(c1)-c1ccc(cc1[N+]([O-])=O)S(=O)(=O)Nc1ccccc1 InChI=1S/C22H15FN4O6S/c23-15-6-9-21(28)18(10-15)22(29)14-12-24-26(13-14)19-8-7-17(11-20(19)27(30)31)34(32,33)25-16-4-2-1-3-5-16/h1-13,25,28H SEIFYKVCGHTWKI-UHFFFAOYSA-N 88622 4-[4-[(5-fluoro-2-hydroxyphenyl)-oxomethyl]-1-pyrazolyl]-3-nitro-N-phenylbenzenesulfonamide::4-[4-(5-fluoranyl-2-oxidanyl-phenyl)carbonylpyrazol-1-yl]-3-nitro-N-phenyl-benzenesulfonamide::4-[4-(5-fluoro-2-hydroxybenzoyl)pyrazol-1-yl]-3-nitro-N-phenylbenzenesulfonamide::cid_5022720::MLS000393486::SMR000241330::4-[4-(5-fluoro-2-hydroxy-benzoyl)pyrazol-1-yl]-3-nitro-N-phenyl-benzenesulfonamide Melanocortin receptor 4 Homo sapiens >64599 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88622 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88622&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5022720 252660289 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192948 Cc1c(Cl)sn(-c2ccc(Cl)cc2)c1=O InChI=1S/C10H7Cl2NOS/c1-6-9(12)15-13(10(6)14)8-4-2-7(11)3-5-8/h2-5H,1H3 NCUQEDWZGMYONC-UHFFFAOYSA-N 53623 MLS000684518::SMR000269693::5-chloro-2-(4-chlorophenyl)-4-methyl-3(2H)-isothiazolone::cid_759209::5-chloro-2-(4-chlorophenyl)-4-methyl-3-isothiazolone::5-chloranyl-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one::5-chloro-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one::5-chloro-2-(4-chlorophenyl)-4-methyl-4-isothiazolin-3-one Melanocortin receptor 4 Homo sapiens 3745 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53623&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 759209 252633663 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192949 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc1ccccc1C(=O)N1CCCC1 InChI=1S/C18H16ClN3O4/c19-14-8-7-12(11-16(14)22(25)26)17(23)20-15-6-2-1-5-13(15)18(24)21-9-3-4-10-21/h1-2,5-8,11H,3-4,9-10H2,(H,20,23) LEYHSXNQCGYETJ-UHFFFAOYSA-N 61820 4-chloranyl-3-nitro-N-(2-pyrrolidin-1-ylcarbonylphenyl)benzamide::4-chloro-3-nitro-N-[2-[oxo(1-pyrrolidinyl)methyl]phenyl]benzamide::SMR000271706::cid_1326639::4-chloro-3-nitro-N-[2-(1-pyrrolidinylcarbonyl)phenyl]benzamide::MLS000677547::4-chloro-3-nitro-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzamide Melanocortin receptor 4 Homo sapiens 20630 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61820 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61820&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1326639 252640972 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192950 COc1cc(ccc1NC(=S)NC(=O)CC(C)(C)C)[N+]([O-])=O InChI=1S/C14H19N3O4S/c1-14(2,3)8-12(18)16-13(22)15-10-6-5-9(17(19)20)7-11(10)21-4/h5-7H,8H2,1-4H3,(H2,15,16,18,22) HHLLFMRXGOHNAH-UHFFFAOYSA-N 88623 N-[(2-methoxy-4-nitrophenyl)carbamothioyl]-3,3-dimethylbutanamide::N-[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]-3,3-dimethylbutanamide::cid_2963653::N-{[(2-methoxy-4-nitrophenyl)amino]carbonothioyl}-3,3-dimethylbutanamide::N-[(2-methoxy-4-nitro-phenyl)carbamothioyl]-3,3-dimethyl-butanamide::SMR000295231::MLS000624608::N-[(2-methoxy-4-nitro-phenyl)thiocarbamoyl]-3,3-dimethyl-butyramide Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88623 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88623&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2963653 252660290 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192951 CC(C)C1CC(CCNCc2ccc3OCOc3c2)(CCO1)c1ccccc1 InChI=1S/C24H31NO3/c1-18(2)23-15-24(11-13-26-23,20-6-4-3-5-7-20)10-12-25-16-19-8-9-21-22(14-19)28-17-27-21/h3-9,14,18,23,25H,10-13,15-17H2,1-2H3 CNIGJORLWLOETQ-UHFFFAOYSA-N 88624 N-(1,3-benzodioxol-5-ylmethyl)-2-(2-isopropyl-4-phenyltetrahydro-2H-pyran-4-yl)ethanamine hydrochloride::N-(1,3-benzodioxol-5-ylmethyl)-2-(4-phenyl-2-propan-2-yl-oxan-4-yl)ethanamine;hydrochloride::N-(1,3-benzodioxol-5-ylmethyl)-2-(4-phenyl-2-propan-2-yloxan-4-yl)ethanamine;hydrochloride::MLS000662203::SMR000293104::cid_2946034::N-(1,3-benzodioxol-5-ylmethyl)-2-(4-phenyl-2-propan-2-yl-4-oxanyl)ethanamine;hydrochloride::2-(2-isopropyl-4-phenyl-tetrahydropyran-4-yl)ethyl-piperonyl-amine;hydrochloride Melanocortin receptor 4 Homo sapiens >64585 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88624 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88624&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2946035 252660291 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192952 COc1cccc(C(=O)Nc2sc(cc2C(N)=O)C(C)C)c1OC InChI=1S/C17H20N2O4S/c1-9(2)13-8-11(15(18)20)17(24-13)19-16(21)10-6-5-7-12(22-3)14(10)23-4/h5-9H,1-4H3,(H2,18,20)(H,19,21) RFVPUIBACZPPEE-UHFFFAOYSA-N 63476 SMR000295841::2-[[(2,3-dimethoxyphenyl)-oxomethyl]amino]-5-propan-2-yl-3-thiophenecarboxamide::MLS000684170::2-[(2,3-dimethoxyphenyl)carbonylamino]-5-propan-2-yl-thiophene-3-carboxamide::cid_1245133::2-[(2,3-dimethoxybenzoyl)amino]-5-propan-2-ylthiophene-3-carboxamide::2-[(2,3-dimethoxybenzoyl)amino]-5-isopropyl-3-thiophenecarboxamide::5-isopropyl-2-(o-veratroylamino)thiophene-3-carboxamide Melanocortin receptor 4 Homo sapiens >64573 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=63476 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=63476&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1245133 252642584 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192953 OC(=O)c1cc(nc2ccc(Br)cc12)-c1ccc2OCOc2c1 InChI=1S/C17H10BrNO4/c18-10-2-3-13-11(6-10)12(17(20)21)7-14(19-13)9-1-4-15-16(5-9)23-8-22-15/h1-7H,8H2,(H,20,21) FFRGEBFVZFKLSD-UHFFFAOYSA-N 66177 2-(1,3-benzodioxol-5-yl)-6-bromoquinoline-4-carboxylic acid::2-(1,3-benzodioxol-5-yl)-6-bromo-4-quinolinecarboxylic acid::SMR000298218::MLS000673696::cid_1002526::2-(1,3-benzodioxol-5-yl)-6-bromanyl-quinoline-4-carboxylic acid::2-(1,3-benzodioxol-5-yl)-6-bromo-cinchoninic acid Melanocortin receptor 4 Homo sapiens 35729 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66177&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1002526 252644505 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192954 COc1ccc(N(C(C(=O)NC2CCCC2)c2cccs2)C(=O)C#C)c(OC)c1 InChI=1S/C22H24N2O4S/c1-4-20(25)24(17-12-11-16(27-2)14-18(17)28-3)21(19-10-7-13-29-19)22(26)23-15-8-5-6-9-15/h1,7,10-15,21H,5-6,8-9H2,2-3H3,(H,23,26) IIZSMPAYISCGST-UHFFFAOYSA-N 88625 N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,4-dimethoxyphenyl)prop-2-ynamide::cid_3216691::SMR000286041::N-[2-(cyclopentylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2,4-dimethoxyphenyl)-2-propynamide::N-[2-(cyclopentylamino)-2-oxidanylidene-1-thiophen-2-yl-ethyl]-N-(2,4-dimethoxyphenyl)prop-2-ynamide::MLS000677248::N-[2-(cyclopentylamino)-2-keto-1-(2-thienyl)ethyl]-N-(2,4-dimethoxyphenyl)propiolamide Melanocortin receptor 4 Homo sapiens >64588 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88625 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88625&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3216691 252660292 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192955 O=C(CNC(=O)C(c1ccccc1)c1ccccc1)OCc1ccccc1 InChI=1S/C23H21NO3/c25-21(27-17-18-10-4-1-5-11-18)16-24-23(26)22(19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,22H,16-17H2,(H,24,26) LZVTUCSZHWLWST-UHFFFAOYSA-N 88626 SMR000283888::2-[(1-oxo-2,2-diphenylethyl)amino]acetic acid (phenylmethyl) ester::benzyl 2-[(2,2-diphenylacetyl)amino]acetate::(phenylmethyl) 2-(2,2-diphenylethanoylamino)ethanoate::cid_1100660::MLS000688236::2-[(2,2-diphenylacetyl)amino]acetic acid benzyl ester Melanocortin receptor 4 Homo sapiens >64589 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88626 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88626&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1100660 252660293 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192956 CCOc1ccc2nc(NC(=O)CSc3nc(-c4ccccc4)c(C#N)c(=O)[nH]3)sc2c1 InChI=1S/C22H17N5O3S2/c1-2-30-14-8-9-16-17(10-14)32-22(24-16)25-18(28)12-31-21-26-19(13-6-4-3-5-7-13)15(11-23)20(29)27-21/h3-10H,2,12H2,1H3,(H,24,25,28)(H,26,27,29) MGIHBMLNJBQIJZ-UHFFFAOYSA-N 53969 cid_2227940::2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide::MLS000862375::SMR000300813::2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydro-2-pyrimidinyl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide::2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide::2-[(5-cyano-4-oxidanylidene-6-phenyl-1H-pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)ethanamide::2-[(5-cyano-4-keto-6-phenyl-1H-pyrimidin-2-yl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide Melanocortin receptor 4 Homo sapiens >64580 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53969 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53969&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2227940 252634004 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192957 CCN(CC)C(=O)C(C)N(C#N)c1nc(Cl)nc(n1)N(C)C InChI=1S/C13H20ClN7O/c1-6-20(7-2)10(22)9(3)21(8-15)13-17-11(14)16-12(18-13)19(4)5/h9H,6-7H2,1-5H3 CQBGETICMZFUPO-UHFFFAOYSA-N 88627 2-[[4-chloro-6-(dimethylamino)-1,3,5-triazin-2-yl]-cyanoamino]-N,N-diethylpropanamide::2-[[4-chloranyl-6-(dimethylamino)-1,3,5-triazin-2-yl]-cyano-amino]-N,N-diethyl-propanamide::MLS000764700::SMR000290305::cid_3130267::2-[[4-chloro-6-(dimethylamino)-s-triazin-2-yl]-cyano-amino]-N,N-diethyl-propionamide Melanocortin receptor 4 Homo sapiens >64568 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88627 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88627&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3130267 252660294 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192958 CN(C)c1ccc(cc1)-n1cccc1\C=C\[N+]([O-])=O InChI=1S/C14H15N3O2/c1-15(2)12-5-7-14(8-6-12)16-10-3-4-13(16)9-11-17(18)19/h3-11H,1-2H3 PHNKKLDMLMQQKH-UHFFFAOYSA-N 79568 N,N-dimethyl-4-[2-[(E)-2-nitroethenyl]pyrrol-1-yl]aniline::N,N-dimethyl-4-[2-[(E)-2-nitroethenyl]-1-pyrrolyl]aniline::cid_5662106::SMR000288433::MLS000706381::dimethyl-[4-[2-[(E)-2-nitrovinyl]pyrrol-1-yl]phenyl]amine Melanocortin receptor 4 Homo sapiens 12119 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79568 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79568&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5662106 252656216 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192959 ClCC(=O)c1ccc2N(CCc2c1)C(=O)C1CCCCC1 InChI=1S/C17H20ClNO2/c18-11-16(20)14-6-7-15-13(10-14)8-9-19(15)17(21)12-4-2-1-3-5-12/h6-7,10,12H,1-5,8-9,11H2 CYYLHSSSHLLYGL-UHFFFAOYSA-N 71009 cid_1447917::SMR000288426::MLS000706374::2-chloranyl-1-(1-cyclohexylcarbonyl-2,3-dihydroindol-5-yl)ethanone::2-chloro-1-[1-(cyclohexanecarbonyl)-2,3-dihydroindol-5-yl]ethanone::2-chloro-1-[1-[cyclohexyl(oxo)methyl]-2,3-dihydroindol-5-yl]ethanone::2-chloro-1-[1-(cyclohexanecarbonyl)indolin-5-yl]ethanone Melanocortin receptor 4 Homo sapiens >64634 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71009 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71009&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1447917 252648710 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192960 Clc1ccc2c(SCC(=O)NCCN3CCOCC3)c3CCCCc3nc2c1 InChI=1S/C21H26ClN3O2S/c22-15-5-6-17-19(13-15)24-18-4-2-1-3-16(18)21(17)28-14-20(26)23-7-8-25-9-11-27-12-10-25/h5-6,13H,1-4,7-12,14H2,(H,23,26) KIQHBMZYEZFPIQ-UHFFFAOYSA-N 88628 2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-N-(2-morpholin-4-ylethyl)acetamide::2-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-N-(2-morpholin-4-ylethyl)ethanamide::2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-[2-(4-morpholinyl)ethyl]acetamide::SMR000309631::MLS000731356::2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-(2-morpholin-4-ylethyl)acetamide::cid_16193930::2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-(2-morpholinoethyl)acetamide Melanocortin receptor 4 Homo sapiens >64574 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88628 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88628&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16193930 252660295 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192961 CC(C)C1=NN2C(S1)=NC(=O)\C(=C\c1cccn1-c1ccc(C)cc1)C2=N |c:8,t:3| InChI=1S/C20H19N5OS/c1-12(2)19-23-25-17(21)16(18(26)22-20(25)27-19)11-15-5-4-10-24(15)14-8-6-13(3)7-9-14/h4-12,21H,1-3H3 LFLAWWCWAWCTAM-UHFFFAOYSA-N 88629 SMR000309176::(6E)-5-imino-6-[[1-(4-methylphenyl)-2-pyrrolyl]methylidene]-2-propan-2-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6E)-5-imino-6-[[1-(4-methylphenyl)pyrrol-2-yl]methylidene]-2-propan-2-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::cid_16194436::(6E)-5-azanylidene-6-[[1-(4-methylphenyl)pyrrol-2-yl]methylidene]-2-propan-2-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::MLS000871657::(6E)-5-imino-2-isopropyl-6-{[1-(4-methylphenyl)-1H-pyrrol-2-yl]methylene}-5,6-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6E)-5-imino-2-isopropyl-6-[[1-(p-tolyl)pyrrol-2-yl]methylene]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one Melanocortin receptor 4 Homo sapiens >64591 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88629 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88629&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16194436 252660296 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192962 COc1ccc(NC(=O)C(Cl)=C(Cl)S(=O)Cc2ccc(Cl)cc2)cn1 |w:11.11| InChI=1S/C16H13Cl3N2O3S/c1-24-13-7-6-12(8-20-13)21-16(22)14(18)15(19)25(23)9-10-2-4-11(17)5-3-10/h2-8H,9H2,1H3,(H,21,22) YHPGXJXWMDNSDU-UHFFFAOYSA-N 43465 SMR000334340::(Z)-2,3-dichloro-3-[(4-chlorophenyl)methylsulfinyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide::(Z)-2,3-dichloro-3-[(4-chlorophenyl)methylsulfinyl]-N-(6-methoxy-3-pyridinyl)-2-propenamide::MLS000706843::2,3-dichloro-3-[(4-chlorobenzyl)sulfinyl]-N-(6-methoxy-3-pyridinyl)acrylamide::(Z)-2,3-bis(chloranyl)-3-[(4-chlorophenyl)methylsulfinyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide::cid_1472220::(Z)-2,3-dichloro-3-(4-chlorobenzyl)sulfinyl-N-(6-methoxy-3-pyridyl)acrylamide Melanocortin receptor 4 Homo sapiens 9966 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43465 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43465&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1472220 252624145 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192963 FC(F)(F)c1cnc(NCCN2C(=O)C=CC2=O)c(Cl)c1 |c:14| InChI=1S/C12H9ClF3N3O2/c13-8-5-7(12(14,15)16)6-18-11(8)17-3-4-19-9(20)1-2-10(19)21/h1-2,5-6H,3-4H2,(H,17,18) XRJVXAMPYWOKBH-UHFFFAOYSA-N 47443 1-[2-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]ethyl]pyrrole-2,5-dione::SMR000333762::1-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]ethyl]pyrrole-2,5-dione::1-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)-1H-pyrrole-2,5-dione::cid_1486292::1-[2-[[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]amino]ethyl]pyrrole-2,5-dione::MLS000692082::1-[2-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]amino]ethyl]-3-pyrroline-2,5-quinone Melanocortin receptor 4 Homo sapiens 12255 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47443 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47443&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1486292 252627755 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192964 Cc1ncn(n1)-c1ccc(cn1)C(=O)Oc1ccccc1 InChI=1S/C15H12N4O2/c1-11-17-10-19(18-11)14-8-7-12(9-16-14)15(20)21-13-5-3-2-4-6-13/h2-10H,1H3 ZSILXSCVEFUHGU-UHFFFAOYSA-N 88630 MLS000721855::SMR000337015::phenyl 6-(3-methyl-1H-1,2,4-triazol-1-yl)nicotinate::6-(3-methyl-1,2,4-triazol-1-yl)-3-pyridinecarboxylic acid phenyl ester::cid_1475893::phenyl 6-(3-methyl-1,2,4-triazol-1-yl)pyridine-3-carboxylate::6-(3-methyl-1,2,4-triazol-1-yl)nicotinic acid phenyl ester Melanocortin receptor 4 Homo sapiens >64542 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88630 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88630&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1475893 252660297 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192965 [#6]-[#6]-[#8]-[#6](=O)-[#6](=[#6]\c1ccc(cc1)-n1ccnc1)\[#6](=O)-[#8]-[#6]-[#6] InChI=1S/C17H7N2O4/c1-3-22-16(20)15(17(21)23-4-2)11-13-5-7-14(8-6-13)19-10-9-18-12-19/h5-10,12H WKZKMVURVKYRCK-UHFFFAOYSA-N 88631 SMR000337506::diethyl 2-{[4-(1H-imidazol-1-yl)phenyl]methylene}malonate::MLS000755834::diethyl 2-[(4-imidazol-1-ylphenyl)methylidene]propanedioate::cid_3296286::2-[[4-(1-imidazolyl)phenyl]methylidene]propanedioic acid diethyl ester::2-(4-imidazol-1-ylbenzylidene)malonic acid diethyl ester Melanocortin receptor 4 Homo sapiens >64626 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88631 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88631&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3296286 252660298 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192966 Cc1cc2nccc(-c3ccc(Cl)c(c3)[N+]([O-])=O)n2n1 InChI=1S/C13H9ClN4O2/c1-8-6-13-15-5-4-11(17(13)16-8)9-2-3-10(14)12(7-9)18(19)20/h2-7H,1H3 YPPJYLAKEAKYPC-UHFFFAOYSA-N 88632 SMR000335948::7-(4-chloranyl-3-nitro-phenyl)-2-methyl-pyrazolo[1,5-a]pyrimidine::cid_1489154::MLS000720448::7-(4-chloro-3-nitrophenyl)-2-methylpyrazolo[1,5-a]pyrimidine::7-(4-chloro-3-nitro-phenyl)-2-methyl-pyrazolo[1,5-a]pyrimidine Melanocortin receptor 4 Homo sapiens >64630 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88632 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88632&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1489154 252660299 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192967 COC(=O)CSc1[nH]c2ccc(F)cc2c1[N+]([O-])=O InChI=1S/C11H9FN2O4S/c1-18-9(15)5-19-11-10(14(16)17)7-4-6(12)2-3-8(7)13-11/h2-4,13H,5H2,1H3 HLNVLIYWSQDJAD-UHFFFAOYSA-N 65882 SMR000287841::methyl 2-[(5-fluoranyl-3-nitro-1H-indol-2-yl)sulfanyl]ethanoate::MLS000708374::cid_750417::methyl 2-[(5-fluoro-3-nitro-1H-indol-2-yl)sulfanyl]acetate::2-[(5-fluoro-3-nitro-1H-indol-2-yl)thio]acetic acid methyl ester Melanocortin receptor 4 Homo sapiens >64572 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65882 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65882&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 750417 252644217 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192968 O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2ccc(-[#16]-[#6]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)-[#6](=O)-[#7]-1 InChI=1S/C15H2N2O4S/c18-13-11(14(19)17-15(20)16-13)8-9-6-7-12(21-9)22-10-4-2-1-3-5-10/h6-7H POTVPEZRRBBBGK-UHFFFAOYSA-N 61707 SMR000309359::MLS000730984::5-{[5-(cyclohexylthio)-2-furyl]methylene}pyrimidine-2,4,6(1H,3H,5H)-trione::5-[(5-cyclohexylsulfanylfuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione::5-[[5-(cyclohexylthio)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione::cid_16195600::5-[[5-(cyclohexylthio)-2-furyl]methylene]barbituric acid Melanocortin receptor 4 Homo sapiens >21521 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61707 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61707&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16195600 252640860 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192969 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc1ccccc1N1CCCCC1 InChI=1S/C18H18ClN3O3/c19-14-9-8-13(12-17(14)22(24)25)18(23)20-15-6-2-3-7-16(15)21-10-4-1-5-11-21/h2-3,6-9,12H,1,4-5,10-11H2,(H,20,23) GQWCXWWIHJSIII-UHFFFAOYSA-N 88633 4-chloro-3-nitro-N-[2-(1-piperidinyl)phenyl]benzamide::cid_2161746::4-chloranyl-3-nitro-N-(2-piperidin-1-ylphenyl)benzamide::MLS000517347::SMR000343460::4-chloro-3-nitro-N-(2-piperidin-1-ylphenyl)benzamide::4-chloro-3-nitro-N-(2-piperidinophenyl)benzamide Melanocortin receptor 4 Homo sapiens >64586 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88633 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88633&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2161746 252660300 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192970 [O-][N+](=O)c1cccc2C(=O)N(CCC(=O)OCC(=O)NCc3ccccc3)C(=O)c12 InChI=1S/C20H17N3O7/c24-16(21-11-13-5-2-1-3-6-13)12-30-17(25)9-10-22-19(26)14-7-4-8-15(23(28)29)18(14)20(22)27/h1-8H,9-12H2,(H,21,24) NIYIRZIBOQQXDT-UHFFFAOYSA-N 56713 cid_2404497::[2-oxidanylidene-2-[(phenylmethyl)amino]ethyl] 3-[4-nitro-1,3-bis(oxidanylidene)isoindol-2-yl]propanoate::3-(4-nitro-1,3-dioxo-2-isoindolyl)propanoic acid [2-oxo-2-[(phenylmethyl)amino]ethyl] ester::[2-(benzylamino)-2-oxoethyl] 3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoate::MLS001005301::SMR000348603::3-(1,3-diketo-4-nitro-isoindolin-2-yl)propionic acid [2-(benzylamino)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64568 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=56713 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=56713&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2404497 252636671 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192971 Cc1nn(CC(=O)OCC(=O)NCc2ccc(C)cc2)c(C)c1[N+]([O-])=O InChI=1S/C17H20N4O5/c1-11-4-6-14(7-5-11)8-18-15(22)10-26-16(23)9-20-13(3)17(21(24)25)12(2)19-20/h4-7H,8-10H2,1-3H3,(H,18,22) NKGLOIJKAQUZPF-UHFFFAOYSA-N 88634 SMR000353823::MLS001017601::cid_2126229::[2-[(4-methylphenyl)methylamino]-2-oxoethyl] 2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetate::[2-[(4-methylphenyl)methylamino]-2-oxidanylidene-ethyl] 2-(3,5-dimethyl-4-nitro-pyrazol-1-yl)ethanoate::2-(3,5-dimethyl-4-nitro-1-pyrazolyl)acetic acid [2-[(4-methylphenyl)methylamino]-2-oxoethyl] ester::2-(3,5-dimethyl-4-nitro-pyrazol-1-yl)acetic acid [2-keto-2-[(4-methylbenzyl)amino]ethyl] ester Melanocortin receptor 4 Homo sapiens 14404 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88634&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2126229 252660301 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192972 CN(C(=O)COC(=O)CNC(=O)c1ccc(Cl)cc1Cl)c1ccccc1 InChI=1S/C18H16Cl2N2O4/c1-22(13-5-3-2-4-6-13)16(23)11-26-17(24)10-21-18(25)14-8-7-12(19)9-15(14)20/h2-9H,10-11H2,1H3,(H,21,25) AJDUDPWRLIMVAH-UHFFFAOYSA-N 88635 [2-[methyl(phenyl)amino]-2-oxidanylidene-ethyl] 2-[(2,4-dichlorophenyl)carbonylamino]ethanoate::SMR000348067::MLS001004438::2-[[(2,4-dichlorophenyl)-oxomethyl]amino]acetic acid [2-(N-methylanilino)-2-oxoethyl] ester::[2-(N-methylanilino)-2-oxoethyl] 2-[(2,4-dichlorobenzoyl)amino]acetate::cid_2492526::2-[(2,4-dichlorobenzoyl)amino]acetic acid [2-keto-2-(N-methylanilino)ethyl] ester Melanocortin receptor 4 Homo sapiens >64595 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88635 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88635&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2492526 252660302 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192973 CN1CCN(CC1)C(=O)\C=C\c1cn(nc1-c1ccc2OCCOc2c1)-c1ccccc1 InChI=1S/C25H26N4O3/c1-27-11-13-28(14-12-27)24(30)10-8-20-18-29(21-5-3-2-4-6-21)26-25(20)19-7-9-22-23(17-19)32-16-15-31-22/h2-10,17-18H,11-16H2,1H3 NAACUODJWGVTLU-UHFFFAOYSA-N 88636 (E)-3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-pyrazol-4-yl]-1-(4-methylpiperazin-1-yl)prop-2-en-1-one;hydrochloride::cid_16196078::MLS001017984::(E)-3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-4-pyrazolyl]-1-(4-methyl-1-piperazinyl)-2-propen-1-one;hydrochloride::(E)-3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenylpyrazol-4-yl]-1-(4-methylpiperazin-1-yl)prop-2-en-1-one;hydrochloride::SMR000354251::(E)-3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-phenyl-pyrazol-4-yl]-1-(4-methylpiperazino)prop-2-en-1-one;hydrochloride Melanocortin receptor 4 Homo sapiens >64555 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88636 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88636&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2347668 252660303 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192974 Cc1ccc(cc1)-c1nn(cc1NC(=O)CCl)-c1ccccc1 InChI=1S/C18H16ClN3O/c1-13-7-9-14(10-8-13)18-16(20-17(23)11-19)12-22(21-18)15-5-3-2-4-6-15/h2-10,12H,11H2,1H3,(H,20,23) WTUJTYDYKXFWIR-UHFFFAOYSA-N 77785 MLS000770839::2-chloro-N-[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]acetamide::2-chloro-N-[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]acetamide::cid_2104090::SMR000344083::2-chloranyl-N-[3-(4-methylphenyl)-1-phenyl-pyrazol-4-yl]ethanamide::2-chloro-N-[1-phenyl-3-(p-tolyl)pyrazol-4-yl]acetamide Melanocortin receptor 4 Homo sapiens >7177 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77785 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77785&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2104090 252654699 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192975 CCOC(=O)c1sc(NC(=O)CCN2CCN(CC)CC2)c(C(=O)OCC)c1C InChI=1S/C20H31N3O5S/c1-5-22-10-12-23(13-11-22)9-8-15(24)21-18-16(19(25)27-6-2)14(4)17(29-18)20(26)28-7-3/h5-13H2,1-4H3,(H,21,24) KIXWJXQGZKHFMX-UHFFFAOYSA-N 88637 diethyl 5-[3-(4-ethylpiperazin-1-yl)propanoylamino]-3-methyl-thiophene-2,4-dicarboxylate::diethyl 5-[3-(4-ethylpiperazin-1-yl)propanoylamino]-3-methylthiophene-2,4-dicarboxylate::cid_1183197::SMR000353139::MLS001011145::5-[[3-(4-ethyl-1-piperazinyl)-1-oxopropyl]amino]-3-methylthiophene-2,4-dicarboxylic acid diethyl ester::5-[3-(4-ethylpiperazino)propanoylamino]-3-methyl-thiophene-2,4-dicarboxylic acid diethyl ester Melanocortin receptor 4 Homo sapiens >64577 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88637 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88637&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1183197 252660304 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192976 CC(C)Cn1c(N)c(C(=O)COC(=O)c2ccc(o2)[N+]([O-])=O)c(=O)n(C)c1=O InChI=1S/C16H18N4O8/c1-8(2)6-19-13(17)12(14(22)18(3)16(19)24)9(21)7-27-15(23)10-4-5-11(28-10)20(25)26/h4-5,8H,6-7,17H2,1-3H3 VHNQORPGZFTBNO-UHFFFAOYSA-N 72610 cid_2084008::[2-[4-azanyl-1-methyl-3-(2-methylpropyl)-2,6-bis(oxidanylidene)pyrimidin-5-yl]-2-oxidanylidene-ethyl] 5-nitrofuran-2-carboxylate::5-nitro-2-furancarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester::MLS001004611::SMR000348105::[2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxopyrimidin-5-yl]-2-oxoethyl] 5-nitrofuran-2-carboxylate::5-nitrofuran-2-carboxylic acid [2-(6-amino-1-isobutyl-2,4-diketo-3-methyl-pyrimidin-5-yl)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64640 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72610 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72610&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2084008 252649868 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192977 COc1ccc(CCn2c(C)cc(C(=O)CCl)c2C)cc1OC InChI=1S/C18H22ClNO3/c1-12-9-15(16(21)11-19)13(2)20(12)8-7-14-5-6-17(22-3)18(10-14)23-4/h5-6,9-10H,7-8,11H2,1-4H3 GTRXJYISJOBLEB-UHFFFAOYSA-N 45669 MLS000877957::cid_2526884::SMR000376940::2-chloranyl-1-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,5-dimethyl-pyrrol-3-yl]ethanone::2-chloro-1-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone::2-chloro-1-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,5-dimethylpyrrol-3-yl]ethanone::2-chloro-1-(1-homoveratryl-2,5-dimethyl-pyrrol-3-yl)ethanone Melanocortin receptor 4 Homo sapiens >64597 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=45669 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=45669&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2526884 252626264 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192978 CCN(c1ccc(OCC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1)S(=O)(=O)c1ccccc1 InChI=1S/C24H26N4O8S/c1-4-28(37(33,34)18-8-6-5-7-9-18)16-10-12-17(13-11-16)35-15-20(30)36-14-19(29)21-22(25)26(2)24(32)27(3)23(21)31/h5-13H,4,14-15,25H2,1-3H3 SZYUMEQASWYGJJ-UHFFFAOYSA-N 88638 MLS000773980::cid_2358776::[2-(4-amino-1,3-dimethyl-2,6-dioxopyrimidin-5-yl)-2-oxoethyl] 2-[4-[benzenesulfonyl(ethyl)amino]phenoxy]acetate::[2-[4-azanyl-1,3-dimethyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]-2-oxidanylidene-ethyl] 2-[4-[ethyl(phenylsulfonyl)amino]phenoxy]ethanoate::2-[4-[benzenesulfonyl(ethyl)amino]phenoxy]acetic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester::SMR000364808::2-[4-[besyl(ethyl)amino]phenoxy]acetic acid [2-(4-amino-2,6-diketo-1,3-dimethyl-pyrimidin-5-yl)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >7176 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88638 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88638&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2358776 252660305 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192979 [O-][N+](=O)c1cc(NC(=O)C2CN(Cc3ccccc3)C(=O)C2)ccc1F InChI=1S/C18H16FN3O4/c19-15-7-6-14(9-16(15)22(25)26)20-18(24)13-8-17(23)21(11-13)10-12-4-2-1-3-5-12/h1-7,9,13H,8,10-11H2,(H,20,24) MWUZMCTYZYVMQS-UHFFFAOYSA-N 88639 cid_4884316::N-(4-fluoranyl-3-nitro-phenyl)-5-oxidanylidene-1-(phenylmethyl)pyrrolidine-3-carboxamide::1-benzyl-N-(4-fluoro-3-nitrophenyl)-5-oxopyrrolidine-3-carboxamide::N-(4-fluoro-3-nitrophenyl)-5-oxo-1-(phenylmethyl)-3-pyrrolidinecarboxamide::MLS001006238::SMR000384316::1-benzyl-N-(4-fluoro-3-nitro-phenyl)-5-keto-pyrrolidine-3-carboxamide Melanocortin receptor 4 Homo sapiens >64568 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88639 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88639&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4884316 252660306 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192980 OC(=O)c1cc(nc2ccccc12)-c1ccc(Cl)s1 InChI=1S/C14H8ClNO2S/c15-13-6-5-12(19-13)11-7-9(14(17)18)8-3-1-2-4-10(8)16-11/h1-7H,(H,17,18) GNBCDNSGZAPUEF-UHFFFAOYSA-N 50097098 CHEMBL153072::cid_625773::2-(5-Chloro-thiophen-2-yl)-quinoline-4-carboxylic acid Melanocortin receptor 4 Homo sapiens >64555 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097098 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097098&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 625773 103994492 CHEMBL153072 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192981 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccccc2F)c1 InChI=1S/C21H26FN3O4S/c1-3-25(4-2)30(27,28)16-9-10-20(24-11-13-29-14-12-24)19(15-16)23-21(26)17-7-5-6-8-18(17)22/h5-10,15H,3-4,11-14H2,1-2H3,(H,23,26) QYOCPSHCKDARSV-UHFFFAOYSA-N 88640 N-[5-(diethylsulfamoyl)-2-morpholin-4-ylphenyl]-2-fluorobenzamide::MLS000760665::N-[5-(diethylsulfamoyl)-2-morpholin-4-yl-phenyl]-2-fluoranyl-benzamide::cid_16196854::N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2-fluorobenzamide::SMR000370585::N-[5-(diethylsulfamoyl)-2-morpholino-phenyl]-2-fluoro-benzamide Melanocortin receptor 4 Homo sapiens >64587 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88640 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88640&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16196854 252660307 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192982 Cc1cc(C(=O)CCl)c(C)n1CCc1ccc(F)cc1 InChI=1S/C16H17ClFNO/c1-11-9-15(16(20)10-17)12(2)19(11)8-7-13-3-5-14(18)6-4-13/h3-6,9H,7-8,10H2,1-2H3 HNAVZTPPCSBHJP-UHFFFAOYSA-N 88641 2-chloro-1-[1-[2-(4-fluorophenyl)ethyl]-2,5-dimethylpyrrol-3-yl]ethanone::MLS000517132::cid_2442137::2-chloro-1-[1-[2-(4-fluorophenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone::SMR000343220::2-chloranyl-1-[1-[2-(4-fluorophenyl)ethyl]-2,5-dimethyl-pyrrol-3-yl]ethanone::2-chloro-1-[1-[2-(4-fluorophenyl)ethyl]-2,5-dimethyl-pyrrol-3-yl]ethanone Melanocortin receptor 4 Homo sapiens >64516 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88641 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88641&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2442137 252660308 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192983 CC(=O)n1cc(N(C(=O)CCl)c2ccc(C)cc2)c2ccccc12 InChI=1S/C19H17ClN2O2/c1-13-7-9-15(10-8-13)22(19(24)11-20)18-12-21(14(2)23)17-6-4-3-5-16(17)18/h3-10,12H,11H2,1-2H3 NGYOGKGATBXFQL-UHFFFAOYSA-N 54370 N-(1-acetylindol-3-yl)-2-chloro-N-(4-methylphenyl)acetamide::MLS000332636::cid_900031::N-(1-acetyl-3-indolyl)-2-chloro-N-(4-methylphenyl)acetamide::N-(1-Acetyl-1H-indol-3-yl)-2-chloro-N-p-tolyl-acetamide::SMR000435967::2-chloranyl-N-(1-ethanoylindol-3-yl)-N-(4-methylphenyl)ethanamide::N-(1-acetylindol-3-yl)-2-chloro-N-(p-tolyl)acetamide Melanocortin receptor 4 Homo sapiens >64598 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54370 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54370&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 900031 252634400 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192984 CN(C)S(=O)(=O)c1ccc(cc1)-c1csc(N=NCc2ccc(O)cc2)n1 |w:16.16| InChI=1S/C18H18N4O3S2/c1-22(2)27(24,25)16-9-5-14(6-10-16)17-12-26-18(20-17)21-19-11-13-3-7-15(23)8-4-13/h3-10,12,23H,11H2,1-2H3 BCJUERWJFMEYJN-UHFFFAOYSA-N 58043 N,N-dimethyl-4-[2-[2-[(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-1,3-thiazol-4-yl]benzenesulfonamide::N,N-dimethyl-4-[2-[2-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-1,3-thiazol-4-yl]benzenesulfonamide::N,N-dimethyl-4-[2-[(4-oxo-1-cyclohexa-2,5-dienylidene)methylhydrazo]-4-thiazolyl]benzenesulfonamide::4-(2-{N'-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazino}-thiazol-4-yl)-N,N-dimethyl-benzenesulfonam ide::MLS000778016::SMR000414410::cid_5879183::4-[2-[N'-[(4-ketocyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]thiazol-4-yl]-N,N-dimethyl-benzenesulfonamide Melanocortin receptor 4 Homo sapiens >64591 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=58043 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=58043&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 91897349 252637959 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192985 CC(=O)n1cc(N(C(=O)CCl)c2ccc(Cl)cc2)c2ccccc12 InChI=1S/C18H14Cl2N2O2/c1-12(23)21-11-17(15-4-2-3-5-16(15)21)22(18(24)10-19)14-8-6-13(20)7-9-14/h2-9,11H,10H2,1H3 QWJCBDOFCRYVGC-UHFFFAOYSA-N 71167 cid_2017227::MLS000333023::N-(1-Acetyl-1H-indol-3-yl)-2-chloro-N-(4-chloro-phenyl)-acetamide::N-(1-acetyl-3-indolyl)-2-chloro-N-(4-chlorophenyl)acetamide::SMR000436335::2-chloranyl-N-(4-chlorophenyl)-N-(1-ethanoylindol-3-yl)ethanamide::N-(1-acetylindol-3-yl)-2-chloro-N-(4-chlorophenyl)acetamide Melanocortin receptor 4 Homo sapiens >64542 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71167&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2017227 252648742 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192986 COc1ccccc1C1(CCNC(C)c2cccs2)CCOC(C1)C(C)C InChI=1S/C23H33NO2S/c1-17(2)21-16-23(12-14-26-21,19-8-5-6-9-20(19)25-4)11-13-24-18(3)22-10-7-15-27-22/h5-10,15,17-18,21,24H,11-14,16H2,1-4H3 CEYBVEUXOMNZSU-UHFFFAOYSA-N 88642 cid_3706223::{2-[2-Isopropyl-4-(2-methoxy-phenyl)-tetrahydro-pyran-4-yl]-ethyl}-(1-thiophen-2-yl-ethyl)-amine::MLS000332237::N-[2-[4-(2-methoxyphenyl)-2-propan-2-yl-oxan-4-yl]ethyl]-1-thiophen-2-yl-ethanamine::N-[2-[4-(2-methoxyphenyl)-2-propan-2-yloxan-4-yl]ethyl]-1-thiophen-2-ylethanamine::N-[2-[4-(2-methoxyphenyl)-2-propan-2-yl-4-oxanyl]ethyl]-1-thiophen-2-ylethanamine::SMR000434899::2-[2-isopropyl-4-(2-methoxyphenyl)tetrahydropyran-4-yl]ethyl-[1-(2-thienyl)ethyl]amine Melanocortin receptor 4 Homo sapiens 10059 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88642 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88642&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3706223 252660309 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192987 CC(C)c1cc(c(C)cc1O)C1(OC(=O)c2ccccc12)c1cc(C(C)C)c(O)cc1C InChI=1S/C28H30O4/c1-15(2)20-13-23(17(5)11-25(20)29)28(22-10-8-7-9-19(22)27(31)32-28)24-14-21(16(3)4)26(30)12-18(24)6/h7-16,29-30H,1-6H3 LDKDGDIWEUUXSH-UHFFFAOYSA-N 58093 3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzofuran-1-one::3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-1-isobenzofuranone::3,3-bis(2-methyl-4-oxidanyl-5-propan-2-yl-phenyl)-2-benzofuran-1-one::SMR000528039::Thymophthalein::cid_31316::MLS000736489::thymolphthalein Melanocortin receptor 4 Homo sapiens >64584 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=58093 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=58093&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 31316 252638006 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192988 NC(=S)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 InChI=1S/C12H15N5O4S/c13-9-6-4(10(14)22)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)21-12/h1,3,5,7-8,12,18-20H,2H2,(H2,14,22)(H2,13,15,16) XZOKDXWQSCIKCM-UHFFFAOYSA-N 66634 4-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbothioamide::Thiosangivamycin::4-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-pyrrolo[2,3-d]pyrimidinecarbothioamide::MLS000737251::SMR000528487::cid_3580213::4-azanyl-7-[5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbothioamide::4-amino-7-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbothioamide Melanocortin receptor 4 Homo sapiens >64577 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66634 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66634&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3580213 252644955 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192989 Cc1nc2c(sc3nc(N4CCOCC4)c4COC(C)(C)Cc4c23)c(-c2ccccc2)c1C(O)=O InChI=1S/C27H27N3O4S/c1-15-19(26(31)32)20(16-7-5-4-6-8-16)23-22(28-15)21-17-13-27(2,3)34-14-18(17)24(29-25(21)35-23)30-9-11-33-12-10-30/h4-8H,9-14H2,1-3H3,(H,31,32) FLJFZKOURMBWOB-UHFFFAOYSA-N 88643 SMR000413128::MLS000776729::2,2,10-Trimethyl-5-morpholin-4-yl-8-phenyl-1,4-dihydro-2H-3-oxa-7-thia-6,11-diaza-benzo[c]fluorene-9- carboxylic acid::cid_1831123 Melanocortin receptor 4 Homo sapiens 15525 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88643 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88643&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 1831123 242053816 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192990 Cc1c(NC(=O)c2cc(n[nH]2)-c2cc(Cl)ccc2O)c(=O)n(-c2ccccc2)n1C InChI=1S/C21H18ClN5O3/c1-12-19(21(30)27(26(12)2)14-6-4-3-5-7-14)23-20(29)17-11-16(24-25-17)15-10-13(22)8-9-18(15)28/h3-11,28H,1-2H3,(H,23,29)(H,24,25) SQUKZKQFGPOJOH-UHFFFAOYSA-N 88644 (5Z)-5-(3-chloro-6-oxo-1-cyclohexa-2,4-dienylidene)-N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-1,2-dihydropyrazole-3-carboxamide::cid_5586260::MLS000779002::(5Z)-5-(3-chloranyl-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-1,2-dihydropyrazole-3-carboxamide::SMR000415765::(5Z)-5-(3-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,2-dihydropyrazole-3-carboxamide::5-(5-Chloro-2-hydroxy-phenyl)-2H-pyrazole-3-carboxylic acid (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-amide::(5Z)-5-(3-chloro-6-keto-cyclohexa-2,4-dien-1-ylidene)-N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-3-pyrazoline-3-carboxamide Melanocortin receptor 4 Homo sapiens >64593 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88644 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88644&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5586260 252660310 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192991 CC(C)NC(=O)NC(=O)COC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C16H23N3O6S/c1-11(2)17-16(22)18-14(20)10-25-15(21)9-19(4)26(23,24)13-7-5-12(3)6-8-13/h5-8,11H,9-10H2,1-4H3,(H2,17,18,20,22) ZRHURLOBGZUJBM-UHFFFAOYSA-N 88645 [2-oxo-2-(propan-2-ylcarbamoylamino)ethyl] 2-[methyl-(4-methylphenyl)sulfonylamino]acetate::cid_2410031::MLS001003003::[2-oxidanylidene-2-(propan-2-ylcarbamoylamino)ethyl] 2-[methyl-(4-methylphenyl)sulfonyl-amino]ethanoate::SMR000372642::2-[methyl-(4-methylphenyl)sulfonylamino]acetic acid [2-oxo-2-[[oxo-(propan-2-ylamino)methyl]amino]ethyl] ester::2-[methyl(tosyl)amino]acetic acid [2-(isopropylcarbamoylamino)-2-keto-ethyl] ester Melanocortin receptor 4 Homo sapiens >64587 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88645 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88645&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2410031 252660311 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192992 [H][C@@]12CC3C(CC[C@]4(C)C(CC[C@@]34[H])[C@H](C)C3CC(C)=C(CO)C(=O)O3)[C@@]3(C)C(=O)C=C[C@H](O)[C@@]13O2 |c:33,t:21| InChI=1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3 DBRXOUCRJQVYJQ-UHFFFAOYSA-N 68180 SMR000440592::MLS000876826::cid_16745397 Melanocortin receptor 4 Homo sapiens >64575 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68180 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68180&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16745397 242053479 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192993 COc1ccc(cc1)-c1cc([nH]n1)C(=O)Nc1cc(OC)cc(c1)C(=O)Nc1cccc(c1)C(F)(F)F InChI=1S/C26H21F3N4O4/c1-36-20-8-6-15(7-9-20)22-14-23(33-32-22)25(35)31-19-10-16(11-21(13-19)37-2)24(34)30-18-5-3-4-17(12-18)26(27,28)29/h3-14H,1-2H3,(H,30,34)(H,31,35)(H,32,33) QAUXZQDHMVPPEH-UHFFFAOYSA-N 88646 N-[3-methoxy-5-[oxo-[3-(trifluoromethyl)anilino]methyl]phenyl]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide::SMR000453544::cid_16745784::MLS000911494::3-(4-methoxyphenyl)-N-[3-methoxy-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1H-pyrazole-5-carboxamide Melanocortin receptor 4 Homo sapiens >64590 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88646 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88646&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 16745784 252660312 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6 192994 [#6]-[#8]-c1cccc(c1)-[#6](=O)-[#6](\C#N)=[#6](/[#16]-[#6])-[#16]-[#6] InChI=1S/C13H4NO2S2/c1-16-10-6-4-5-9(7-10)12(15)11(8-14)13(17-2)18-3/h4-7H DTBXWRRPQOWHII-UHFFFAOYSA-N 66653 MLS000859112::cid_2819095::2-(3-methoxybenzoyl)-3,3-bis(methylsulfanyl)prop-2-enenitrile::2-(3-methoxybenzoyl)-3,3-di(methylthio)acrylonitrile::2-[(3-methoxyphenyl)-oxomethyl]-3,3-bis(methylthio)-2-propenenitrile::2-(3-methoxyphenyl)carbonyl-3,3-bis(methylsulfanyl)prop-2-enenitrile::SMR000459291::2-m-anisoyl-3,3-bis(methylthio)acrylonitrile Melanocortin receptor 4 Homo sapiens >64564 PubChem 10.7270/Q2FT8JMN aid602298 PubChem, PC 3/6/2012 6/19/2012 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66653 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6546&target=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66653&enzyme=Melanocortin+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2819095 252644974 1 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY 8QJ2,7F58,7F55,7F54,7F53,7PIV,7PIU,7AUE Melanocortin receptor 4 MC4R_HUMAN P32245 B2RAC3 Q16317 Q3MIJ6