BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 238814 Cc1ccc2nc(oc2c1)-c1ccccn1 InChI=1S/C13H10N2O/c1-9-5-6-10-12(8-9)16-13(15-10)11-4-2-3-7-14-11/h2-8H,1H3 FCVLTYALDWKRND-UHFFFAOYSA-N 114962 6-methyl-2-(2-pyridinyl)-1,3-benzoxazole::SMR000013748::MLS000033711::cid_646454::6-methyl-2-pyridin-2-yl-1,3-benzoxazole::6-Methyl-2-pyridin-2-yl-benzooxazole::6-methyl-2-(2-pyridyl)-1,3-benzoxazole Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114962 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114962&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 646454 252664424 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238815 Cn1c(SCc2ccccc2F)nc2cccnc12 InChI=1S/C14H12FN3S/c1-18-13-12(7-4-8-16-13)17-14(18)19-9-10-5-2-3-6-11(10)15/h2-8H,9H2,1H3 FFHQCGKIMJHDFG-UHFFFAOYSA-N 39520 MLS000073602::2-[(2-fluorophenyl)methylsulfanyl]-3-methyl-imidazo[4,5-b]pyridine::2-[(2-fluorophenyl)methylthio]-3-methylimidazo[4,5-b]pyridine::SMR000006767::cid_649231::2-(2-Fluoro-benzylsulfanyl)-3-methyl-3H-imidazo[4,5-b]pyridine::2-[(2-fluorophenyl)methylsulfanyl]-3-methylimidazo[4,5-b]pyridine::2-[(2-fluorobenzyl)thio]-3-methyl-imidazo[4,5-b]pyridine Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39520&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 649231 252620412 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238816 C1CN(CCO1)c1ccc(cc1)-c1nnc(o1)-c1cccs1 InChI=1S/C16H15N3O2S/c1-2-14(22-11-1)16-18-17-15(21-16)12-3-5-13(6-4-12)19-7-9-20-10-8-19/h1-6,11H,7-10H2 NBZCJRUGPOBOJX-UHFFFAOYSA-N 95939 SMR000002070::4-[4-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)phenyl]morpholine::MLS000026817::4-[4-(5-Thiophen-2-yl-[1,3,4]oxadiazol-2-yl)-phenyl]-morpholine::cid_650568::4-[4-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]phenyl]morpholine Oxysterols receptor LXR-beta Homo sapiens 67522 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95939 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 650568 164037183 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238817 Cn1c(NCc2c[nH]c3ccccc23)nc2ccccc12 InChI=1S/C17H16N4/c1-21-16-9-5-4-8-15(16)20-17(21)19-11-12-10-18-14-7-3-2-6-13(12)14/h2-10,18H,11H2,1H3,(H,19,20) FOIVXEQNSMOVOD-UHFFFAOYSA-N 114963 MLS000034035::N-(1H-indol-3-ylmethyl)-1-methyl-benzimidazol-2-amine::(1H-Indol-3-ylmethyl)-(1-methyl-1H-benzoimidazol-2-yl)-amine::SMR000013297::N-(1H-indol-3-ylmethyl)-1-methyl-2-benzimidazolamine::N-(1H-indol-3-ylmethyl)-1-methylbenzimidazol-2-amine::cid_652872::1H-indol-3-ylmethyl-(1-methylbenzimidazol-2-yl)amine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114963 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114963&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652872 252664425 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238818 CCOC(=O)CSc1nc(ccc1C#N)-c1ccncc1 InChI=1S/C15H13N3O2S/c1-2-20-14(19)10-21-15-12(9-16)3-4-13(18-15)11-5-7-17-8-6-11/h3-8H,2,10H2,1H3 PSOFEUJECPFMAT-UHFFFAOYSA-N 39435 cid_657961::MLS000027979::2-[(3-cyano-6-pyridin-4-yl-2-pyridinyl)thio]acetic acid ethyl ester::SMR000038899::ethyl 2-(3-cyano-6-pyridin-4-ylpyridin-2-yl)sulfanylacetate::ethyl 2-(3-cyano-6-pyridin-4-yl-pyridin-2-yl)sulfanylethanoate::2-[[3-cyano-6-(4-pyridyl)-2-pyridyl]thio]acetic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39435&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 657961 252620327 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238819 CN1CCN(CC1)\C=N\c1sc2CCCCCc2c1C#N InChI=1S/C16H22N4S/c1-19-7-9-20(10-8-19)12-18-16-14(11-17)13-5-3-2-4-6-15(13)21-16/h12H,2-10H2,1H3 FCMGAQVDVZZVMS-UHFFFAOYSA-N 114964 MLS000027580::cid_9568654::2-[(E)-(4-methylpiperazin-1-yl)methylideneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile::SMR000037262::2-[(E)-(4-methyl-1-piperazinyl)methylideneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile::2-[(E)-(4-methylpiperazino)methyleneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile Oxysterols receptor LXR-beta Homo sapiens 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114964 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114964&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9568654 252664426 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238820 O=c1[nH]cnc2cc(sc12)-c1ccccc1 InChI=1S/C12H8N2OS/c15-12-11-9(13-7-14-12)6-10(16-11)8-4-2-1-3-5-8/h1-7H,(H,13,14,15) XSAILWORLBSSMS-UHFFFAOYSA-N 114965 SMR000035281::cid_661437::CHEMBL381518::MLS000036657::6-phenyl-1H-thieno[3,2-d]pyrimidin-4-one Oxysterols receptor LXR-beta Homo sapiens 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114965 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114965&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 661437 252664427 CHEMBL381518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238821 COc1cccc(c1)-c1noc(n1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-5-2-4-9(8-10)12-14-13(17-15-12)11-6-3-7-18-11/h2-8H,1H3 NWPANAJPHRXMQR-UHFFFAOYSA-N 39543 3-(3-methoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole::SMR000047269::MLS000083721::cid_665971::3-(3-methoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39543 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39543&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 665971 252620434 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238822 Cc1nn(c(N)c1Sc1ccc(F)cc1)-c1nc(C)cc(C)n1 InChI=1S/C16H16FN5S/c1-9-8-10(2)20-16(19-9)22-15(18)14(11(3)21-22)23-13-6-4-12(17)5-7-13/h4-8H,18H2,1-3H3 UHKSHIBWGZYKCL-UHFFFAOYSA-N 37328 2-(4,6-dimethylpyrimidin-2-yl)-4-(4-fluorophenyl)sulfanyl-5-methylpyrazol-3-amine::MLS000081884::SMR000060530::cid_2321431::2-(4,6-dimethylpyrimidin-2-yl)-4-(4-fluorophenyl)sulfanyl-5-methyl-pyrazol-3-amine::2-(4,6-dimethyl-2-pyrimidinyl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamine::[2-(4,6-dimethylpyrimidin-2-yl)-4-[(4-fluorophenyl)thio]-5-methyl-pyrazol-3-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67520 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37328 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2321431 252618299 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238823 Oc1ccccc1-c1cc([nH]n1)-c1ccc2OCCOc2c1 InChI=1S/C17H14N2O3/c20-15-4-2-1-3-12(15)14-10-13(18-19-14)11-5-6-16-17(9-11)22-8-7-21-16/h1-6,9-10,20H,7-8H2,(H,18,19) BHAIJGZQJXALAJ-UHFFFAOYSA-N 49227 SMR000060538::(6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::MLS000097909::cid_5742561::(6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49227 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49227&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5742561 252629508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238824 O=C(NCCCn1ccnc1)c1cc(on1)-c1cccs1 InChI=1S/C14H14N4O2S/c19-14(16-4-2-6-18-7-5-15-10-18)11-9-12(20-17-11)13-3-1-8-21-13/h1,3,5,7-10H,2,4,6H2,(H,16,19) LRGVDHZAEYAHLG-UHFFFAOYSA-N 49229 N-[3-(1H-imidazol-1-yl)propyl]-5-thien-2-ylisoxazole-3-carboxamide::N-[3-(1-imidazolyl)propyl]-5-thiophen-2-yl-3-isoxazolecarboxamide::cid_3235911::MLS000087245::N-(3-imidazol-1-ylpropyl)-5-thiophen-2-yl-1,2-oxazole-3-carboxamide::SMR000023468::N-(3-imidazol-1-ylpropyl)-5-(2-thienyl)isoxazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49229 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49229&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3235911 252629510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238825 CCOC(=O)c1c(C)oc2c1cc(O)c1ccccc21 InChI=1S/C16H14O4/c1-3-19-16(18)14-9(2)20-15-11-7-5-4-6-10(11)13(17)8-12(14)15/h4-8,17H,3H2,1-2H3 NAYMIPUFIQUKOS-UHFFFAOYSA-N 114966 ethyl 5-hydroxy-2-methylnaphtho[1,2-b]furan-3-carboxylate::MLS000090329::ethyl 2-methyl-5-oxidanyl-benzo[g][1]benzofuran-3-carboxylate::5-hydroxy-2-methyl-3-benzo[g]benzofurancarboxylic acid ethyl ester::SMR000024939::cid_678599::ethyl 5-hydroxy-2-methylbenzo[g][1]benzofuran-3-carboxylate::5-hydroxy-2-methyl-benzo[g]benzofuran-3-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114966 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114966&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 678599 252664428 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238826 N(c1nc(cs1)-c1cccnc1)c1ccccn1 InChI=1S/C13H10N4S/c1-2-7-15-12(5-1)17-13-16-11(9-18-13)10-4-3-6-14-8-10/h1-9H,(H,15,16,17) YVFMRJIXHKPNTN-UHFFFAOYSA-N 50264070 cid_704624::CHEMBL492010::N-(4-(pyridin-3-yl)thiazol-2-yl)pyridin-2-amine Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264070 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 704624 104112192 CHEMBL492010 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238827 O=C(NCCc1ccccc1)c1cc(on1)-c1ccco1 InChI=1S/C16H14N2O3/c19-16(17-9-8-12-5-2-1-3-6-12)13-11-15(21-18-13)14-7-4-10-20-14/h1-7,10-11H,8-9H2,(H,17,19) KSWYOFGMLOJPMD-UHFFFAOYSA-N 114967 SMR000023421::5-(2-furyl)-N-(2-phenylethyl)isoxazole-3-carboxamide::MLS000087198::5-(furan-2-yl)-N-(2-phenylethyl)-1,2-oxazole-3-carboxamide::5-(2-furanyl)-N-(2-phenylethyl)-3-isoxazolecarboxamide::cid_3245765::5-(2-furyl)-N-phenethyl-isoxazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114967 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114967&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3245765 252664429 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238828 CCOC(=O)c1cnc(SCc2ccccc2)nc1N InChI=1S/C14H15N3O2S/c1-2-19-13(18)11-8-16-14(17-12(11)15)20-9-10-6-4-3-5-7-10/h3-8H,2,9H2,1H3,(H2,15,16,17) PMPWPSTVTPCAGQ-UHFFFAOYSA-N 49248 ethyl 4-amino-2-(benzylthio)-5-pyrimidinecarboxylate::MLS000099282::4-amino-2-(phenylmethylthio)-5-pyrimidinecarboxylic acid ethyl ester::SMR000073548::cid_251641::ethyl 4-amino-2-benzylsulfanylpyrimidine-5-carboxylate::ethyl 4-azanyl-2-(phenylmethylsulfanyl)pyrimidine-5-carboxylate::4-amino-2-(benzylthio)pyrimidine-5-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49248 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49248&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 251641 252629529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238829 COc1ccccc1-c1noc(n1)-c1ccco1 InChI=1S/C13H10N2O3/c1-16-10-6-3-2-5-9(10)12-14-13(18-15-12)11-7-4-8-17-11/h2-8H,1H3 OZGJXPIMHWRQIR-UHFFFAOYSA-N 114968 SMR000082053::5-(furan-2-yl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole::MLS000066686::5-(2-furanyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole::cid_1946188::5-(2-furyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114968 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114968&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1946188 252664430 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238830 Cc1ccc(cc1)-c1nnc(Nc2ccccc2)[nH]1 InChI=1S/C15H14N4/c1-11-7-9-12(10-8-11)14-17-15(19-18-14)16-13-5-3-2-4-6-13/h2-10H,1H3,(H2,16,17,18,19) INDCVHFFYIEZRU-UHFFFAOYSA-N 49285 5-(4-methylphenyl)-N-phenyl-1H-1,2,4-triazol-3-amine::SMR000075700::cid_2951125::MLS000097050::phenyl-[5-(p-tolyl)-1H-1,2,4-triazol-3-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49285 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2951125 252629566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238831 Clc1ccc(Nc2nc(cs2)-c2cccs2)nc1 InChI=1S/C12H8ClN3S2/c13-8-3-4-11(14-6-8)16-12-15-9(7-18-12)10-2-1-5-17-10/h1-7H,(H,14,15,16) OSWCDUQDLSLAGR-UHFFFAOYSA-N 49288 5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyridinamine::N-(5-chloro-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(5-chloropyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::MLS000064746::cid_2214576::N-(5-chloranylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000077573::(5-chloro-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49288 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2214576 252629569 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238832 Clc1ccc(NC(=O)c2cc3ccccc3o2)nc1 InChI=1S/C14H9ClN2O2/c15-10-5-6-13(16-8-10)17-14(18)12-7-9-3-1-2-4-11(9)19-12/h1-8H,(H,16,17,18) HOLGMGFRFOWLGQ-UHFFFAOYSA-N 49299 SMR000070589::N-(5-chloranylpyridin-2-yl)-1-benzofuran-2-carboxamide::N-(5-chloropyridin-2-yl)-1-benzofuran-2-carboxamide::N-(5-chloro-2-pyridinyl)-1-benzofuran-2-carboxamide::MLS000061332::cid_673886::N-(5-chloro-2-pyridinyl)-2-benzofurancarboxamide::N-(5-chloro-2-pyridyl)coumarilamide Oxysterols receptor LXR-beta Homo sapiens 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49299 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 673886 252629580 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238833 Cc1cc(cs1)C(=O)NC1=NCCS1 |t:10| InChI=1S/C9H10N2OS2/c1-6-4-7(5-14-6)8(12)11-9-10-2-3-13-9/h4-5H,2-3H2,1H3,(H,10,11,12) MESYCVOFSOUXRI-UHFFFAOYSA-N 114969 N-(4,5-dihydrothiazol-2-yl)-5-methyl-3-thiophenecarboxamide::SMR000080349::cid_1245366::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methyl-3-thiophenecarboxamide::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methylthiophene-3-carboxamide::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methyl-thiophene-3-carboxamide::MLS000065694::5-methyl-N-(2-thiazolin-2-yl)thiophene-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67477 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114969 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114969&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1245366 252664431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238834 COC(=O)C1C(C)Cc2[nH]c(C(=O)OC3CCCCC3)c(C)c2C1=O InChI=1S/C19H25NO5/c1-10-9-13-15(17(21)14(10)18(22)24-3)11(2)16(20-13)19(23)25-12-7-5-4-6-8-12/h10,12,14,20H,4-9H2,1-3H3 SOUPFDNQACDAQX-UHFFFAOYSA-N 44702 cid_2997361::3,6-dimethyl-4-oxo-1,5,6,7-tetrahydroindole-2,5-dicarboxylic acid O2-cyclohexyl ester O5-methyl ester::O2-cyclohexyl O5-methyl 3,6-dimethyl-4-oxidanylidene-1,5,6,7-tetrahydroindole-2,5-dicarboxylate::2-O-cyclohexyl 5-O-methyl 3,6-dimethyl-4-oxo-1,5,6,7-tetrahydroindole-2,5-dicarboxylate::SMR000093486::MLS000116516::4-keto-3,6-dimethyl-1,5,6,7-tetrahydroindole-2,5-dicarboxylic acid O2-cyclohexyl ester O5-methyl ester Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44702 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2997361 252625308 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238835 CC1CCC(CC1)OC(=O)c1[nH]c2CCCC(=O)c2c1C |(16.57,-1.54,;15.03,-1.54,;14.26,-.21,;12.72,-.21,;11.95,-1.54,;12.72,-2.87,;14.26,-2.87,;10.41,-1.54,;9.64,-.21,;10.41,1.13,;8.1,-.21,;7.2,-1.45,;5.75,-.98,;4.41,-1.75,;3.08,-.98,;3.08,.56,;4.41,1.33,;4.41,2.87,;5.75,.56,;7.2,1.03,;7.68,2.5,)| InChI=1S/C17H23NO3/c1-10-6-8-12(9-7-10)21-17(20)16-11(2)15-13(18-16)4-3-5-14(15)19/h10,12,18H,3-9H2,1-2H3 BJFBZCMAPVQWEQ-UHFFFAOYSA-N 44706 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester::SMR000093504::cid_2996853::(4-methylcyclohexyl) 3-methyl-4-oxidanylidene-1,5,6,7-tetrahydroindole-2-carboxylate::MLS000116534::(4-methylcyclohexyl) 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylate::4-keto-3-methyl-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44706 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44706&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2996853 252625312 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238836 CCOC(=O)N1CCC(CC1)NC(=O)c1cc2ccccn2n1 InChI=1S/C16H20N4O3/c1-2-23-16(22)19-9-6-12(7-10-19)17-15(21)14-11-13-5-3-4-8-20(13)18-14/h3-5,8,11-12H,2,6-7,9-10H2,1H3,(H,17,21) YLNAAFSWYCZZKP-UHFFFAOYSA-N 114970 ethyl 4-(pyrazolo[1,5-a]pyridin-2-ylcarbonylamino)piperidine-1-carboxylate::SMR000095352::cid_5307919::4-[[oxo(2-pyrazolo[1,5-a]pyridinyl)methyl]amino]-1-piperidinecarboxylic acid ethyl ester::ethyl 4-(pyrazolo[1,5-a]pyridine-2-carbonylamino)piperidine-1-carboxylate::MLS000118411::4-(pyrazolo[1,5-a]pyridine-2-carbonylamino)piperidine-1-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114970 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114970&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5307919 252664432 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238837 Cc1nn(C(=O)c2cccs2)c(N)c1-c1ccccc1 InChI=1S/C15H13N3OS/c1-10-13(11-6-3-2-4-7-11)14(16)18(17-10)15(19)12-8-5-9-20-12/h2-9H,16H2,1H3 IWLLOIUNYLLJGP-UHFFFAOYSA-N 37176 (5-amino-3-methyl-4-phenyl-1-pyrazolyl)-thiophen-2-ylmethanone::SMR000092900::(5-azanyl-3-methyl-4-phenyl-pyrazol-1-yl)-thiophen-2-yl-methanone::MLS000115895::cid_1263277::(5-amino-3-methyl-4-phenylpyrazol-1-yl)-thiophen-2-ylmethanone::(5-amino-3-methyl-4-phenyl-pyrazol-1-yl)-(2-thienyl)methanone Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37176&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1263277 252618147 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238838 CC(C)Oc1cc(O)c2c(c1)occ(-c1ccc(O)cc1)c2=O InChI=1S/C18H16O5/c1-10(2)23-13-7-15(20)17-16(8-13)22-9-14(18(17)21)11-3-5-12(19)6-4-11/h3-10,19-20H,1-2H3 GBXSXYPMIFTYHI-UHFFFAOYSA-N 37183 cid_5308744::MLS000115520::SMR000092610::3-(4-hydroxyphenyl)-5-oxidanyl-7-propan-2-yloxy-chromen-4-one::5-hydroxy-3-(4-hydroxyphenyl)-7-propan-2-yloxy-1-benzopyran-4-one::5-hydroxy-3-(4-hydroxyphenyl)-7-propan-2-yloxychromen-4-one::5-hydroxy-3-(4-hydroxyphenyl)-7-isopropoxy-chromone Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37183 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37183&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5308744 252618154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238839 CCOc1ccc2nc(NC(=O)Nc3cccs3)sc2c1 InChI=1S/C14H13N3O2S2/c1-2-19-9-5-6-10-11(8-9)21-14(15-10)17-13(18)16-12-4-3-7-20-12/h3-8H,2H2,1H3,(H2,15,16,17,18) JBLGCZDPPLPWSW-UHFFFAOYSA-N 37478 1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-ylurea::cid_4101591::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl-urea::MLS000119982::SMR000096899::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-(2-thienyl)urea Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37478 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37478&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4101591 252618449 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238840 Cn1c(NC(=O)CCc2ccccc2)cc(=O)n(C)c1=O InChI=1S/C15H17N3O3/c1-17-12(10-14(20)18(2)15(17)21)16-13(19)9-8-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3,(H,16,19) PWNLOMKLYXYKRC-UHFFFAOYSA-N 114971 N-(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)-3-phenylpropanamide::N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)-3-phenylpropanamide::cid_2148465::SMR000018868::MLS000103591::N-[1,3-dimethyl-2,6-bis(oxidanylidene)pyrimidin-4-yl]-3-phenyl-propanamide::N-(2,6-diketo-1,3-dimethyl-pyrimidin-4-yl)-3-phenyl-propionamide Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114971 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114971&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2148465 252664433 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238841 CCS(=O)(=O)Nc1cc(ccc1C)-c1nc2cccnc2s1 InChI=1S/C15H15N3O2S2/c1-3-22(19,20)18-13-9-11(7-6-10(13)2)14-17-12-5-4-8-16-15(12)21-14/h4-9,18H,3H2,1-2H3 FUQNNFOLBVVFIR-UHFFFAOYSA-N 114972 N-[2-methyl-5-(2-thiazolo[5,4-b]pyridinyl)phenyl]ethanesulfonamide::MLS000102794::SMR000018258::N-[2-methyl-5-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]ethanesulfonamide::cid_5310341::N-(2-methyl-5-thiazolo[5,4-b]pyridin-2-yl-phenyl)ethanesulfonamide Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114972 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114972&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5310341 252664434 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238842 Cn1c(NC(=O)CCC2CCCCC2)cc(=O)n(C)c1=O InChI=1S/C15H23N3O3/c1-17-12(10-14(20)18(2)15(17)21)16-13(19)9-8-11-6-4-3-5-7-11/h10-11H,3-9H2,1-2H3,(H,16,19) YXMRLWJUDLJHQZ-UHFFFAOYSA-N 114973 cid_2148477::3-cyclohexyl-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)propanamide::SMR000018874::MLS000103599::3-cyclohexyl-N-[1,3-dimethyl-2,6-bis(oxidanylidene)pyrimidin-4-yl]propanamide::3-cyclohexyl-N-(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)propanamide::3-cyclohexyl-N-(2,6-diketo-1,3-dimethyl-pyrimidin-4-yl)propionamide Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114973 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114973&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2148477 252664435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238843 CCCS(=O)(=O)NCc1cn2c(C)csc2n1 InChI=1S/C10H15N3O2S2/c1-3-4-17(14,15)11-5-9-6-13-8(2)7-16-10(13)12-9/h6-7,11H,3-5H2,1-2H3 KKSHWAITTSRIHM-UHFFFAOYSA-N 114974 N-[(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]propane-1-sulfonamide::cid_5310488::MLS000102772::N-[(3-methyl-6-imidazo[2,1-b]thiazolyl)methyl]-1-propanesulfonamide::SMR000018213::N-[(3-methylimidazo[2,1-b]thiazol-6-yl)methyl]propane-1-sulfonamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114974 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114974&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5310488 252664436 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238844 CN(C)c1ccc(Nc2nc(cs2)-c2cccnc2)cc1 InChI=1S/C16H16N4S/c1-20(2)14-7-5-13(6-8-14)18-16-19-15(11-21-16)12-4-3-9-17-10-12/h3-11H,1-2H3,(H,18,19) VQQBVGGMFGFZPI-UHFFFAOYSA-N 33061 SMR000104797::N4,N4-dimethyl-N1-[4-(3-pyridinyl)-2-thiazolyl]benzene-1,4-diamine::N4,N4-dimethyl-N1-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::cid_704601::MLS000108847::4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::dimethyl-[4-[[4-(3-pyridyl)thiazol-2-yl]amino]phenyl]amine Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33061 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 704601 252616191 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238845 Clc1cccc(c1)-c1nnc(o1)-c1ccccc1 InChI=1S/C14H9ClN2O/c15-12-8-4-7-11(9-12)14-17-16-13(18-14)10-5-2-1-3-6-10/h1-9H HFKZYMPEMMAFOG-UHFFFAOYSA-N 48184 cid_259755::MLS000108072::SMR000104035::2-(3-chlorophenyl)-5-phenyl-1,3,4-oxadiazole::2-phenyl-5-(3-chlorophenyl)-1,3,4-oxadiazole (2d) Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48184 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48184&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 259755 252628481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238846 [#6]-[#6]-[#8]-[#6](=O)-[#6](=[#6]/[#6]=[#6]-1/[#6]=[#6]-[#7](-[#6]-[#6]=[#6])-[#6]=[#6]-1)\C#N |c:9,15| InChI=1S/C15N2O2/c1-3-9-17-10-7-13(8-11-17)5-6-14(12-16)15(18)19-4-2 KJOLLQVAOKKPEZ-UHFFFAOYSA-N 42978 ethyl 4-(1-allyl-4(1H)-pyridinylidene)-2-cyano-2-butenoate::MLS000548178::ethyl (Z)-2-cyano-4-(1-prop-2-enylpyridin-4-ylidene)but-2-enoate::(Z)-2-cyano-4-(1-prop-2-enyl-4-pyridinylidene)-2-butenoic acid ethyl ester::SMR000113956::cid_6381056::(Z)-4-(1-allyl-4-pyridylidene)-2-cyano-but-2-enoic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42978 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6381056 252623666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238847 Cc1nc2sc(nn2c(=O)c1Br)-c1ccccc1 InChI=1S/C12H8BrN3OS/c1-7-9(13)11(17)16-12(14-7)18-10(15-16)8-5-3-2-4-6-8/h2-6H,1H3 GUGVCERVYNWYFX-UHFFFAOYSA-N 114975 6-bromanyl-7-methyl-2-phenyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one::SMR000102567::MLS000392047::cid_792220::6-bromo-7-methyl-2-phenyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114975 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114975&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 792220 252664437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238848 CCc1ccc2oc(nc2c1)-c1cccc(N)c1 InChI=1S/C15H14N2O/c1-2-10-6-7-14-13(8-10)17-15(18-14)11-4-3-5-12(16)9-11/h3-9H,2,16H2,1H3 CPAMZMMYEPRNLO-UHFFFAOYSA-N 48214 cid_735963::3-(5-ethyl-1,3-benzoxazol-2-yl)aniline::SMR000122114::3-(5-Ethyl-benzooxazol-2-yl)-phenylamine::MLS000525240::[3-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]amine Oxysterols receptor LXR-beta Homo sapiens 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48214&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 735963 252628511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238849 CCOC(=O)c1cnc(SCCc2ccccc2)nc1N InChI=1S/C15H17N3O2S/c1-2-20-14(19)12-10-17-15(18-13(12)16)21-9-8-11-6-4-3-5-7-11/h3-7,10H,2,8-9H2,1H3,(H2,16,17,18) APNCRASUNSLSDH-UHFFFAOYSA-N 114976 4-Amino-2-phenethylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester::ethyl 4-azanyl-2-(2-phenylethylsulfanyl)pyrimidine-5-carboxylate::cid_864377::SMR000122312::MLS000525438::4-amino-2-(2-phenylethylthio)-5-pyrimidinecarboxylic acid ethyl ester::ethyl 4-amino-2-(2-phenylethylsulfanyl)pyrimidine-5-carboxylate::4-amino-2-(phenethylthio)pyrimidine-5-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114976 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114976&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 864377 252664438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238850 Cc1ccc(cc1)C(N)=NOC(=O)c1ccco1 |w:9.10| InChI=1S/C13H12N2O3/c1-9-4-6-10(7-5-9)12(14)15-18-13(16)11-3-2-8-17-11/h2-8H,1H3,(H2,14,15) ZDEZEPUNRRREQN-UHFFFAOYSA-N 114977 [(Z)-[amino-(4-methylphenyl)methylidene]amino] furan-2-carboxylate::N'-(2-furoyloxy)-4-methylbenzenecarboximidamide::[(Z)-[azanyl-(4-methylphenyl)methylidene]amino] furan-2-carboxylate::2-furancarboxylic acid [(Z)-[amino-(4-methylphenyl)methylidene]amino] ester::cid_9549684::SMR000114333::MLS000548091::furan-2-carboxylic acid [(Z)-[amino(p-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta Homo sapiens 67483 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114977 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114977&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9549684 252664439 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238851 Cc1cccc(c1)C(N)=NOC(=O)c1ccco1 |w:9.10| InChI=1S/C13H12N2O3/c1-9-4-2-5-10(8-9)12(14)15-18-13(16)11-6-3-7-17-11/h2-8H,1H3,(H2,14,15) QKEPUYQNERUQSB-UHFFFAOYSA-N 114978 N'-(2-furoyloxy)-3-methylbenzenecarboximidamide::MLS000533507::SMR000140945::[(Z)-[azanyl-(3-methylphenyl)methylidene]amino] furan-2-carboxylate::2-furancarboxylic acid [(Z)-[amino-(3-methylphenyl)methylidene]amino] ester::cid_5346031::[(Z)-[amino-(3-methylphenyl)methylidene]amino] furan-2-carboxylate::furan-2-carboxylic acid [(Z)-[amino(m-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114978 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5346031 252664440 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238852 COc1cccc(c1)-c1nc2ccccc2s1 InChI=1S/C14H11NOS/c1-16-11-6-4-5-10(9-11)14-15-12-7-2-3-8-13(12)17-14/h2-9H,1H3 HROHCTACUYNNLZ-UHFFFAOYSA-N 49422 cid_833673::SMR000141111::MLS000533667::2-(3-methoxyphenyl)-1,3-benzothiazole Oxysterols receptor LXR-beta Homo sapiens 67479 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49422 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 833673 252629701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238853 Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 |w:8.8| InChI=1S/C15H14N2S/c1-11-3-4-15(7-12(11)2)17-9-14(8-16)13-5-6-18-10-13/h3-7,9-10,14H,1-2H3 NNVITGHWPHCCAR-UHFFFAOYSA-N 49423 (E)-3-[(3,4-dimethylphenyl)amino]-2-thiophen-3-yl-prop-2-enenitrile::SMR000125105::cid_2766393::(E)-3-(3,4-dimethylanilino)-2-(3-thiophenyl)-2-propenenitrile::MLS000539447::(E)-3-(3,4-dimethylanilino)-2-thiophen-3-ylprop-2-enenitrile::(E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonitrile Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49423 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49423&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896797 252629702 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238854 COc1ccccc1-c1noc(n1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-6-3-2-5-9(10)12-14-13(17-15-12)11-7-4-8-18-11/h2-8H,1H3 SVYWWEZMFNQJRZ-UHFFFAOYSA-N 114979 cid_1870209::3-(2-methoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole::SMR000144691::MLS000538854::3-(2-methoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67476 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114979 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114979&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1870209 252664441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238855 Cc1cc(NC(=O)c2nn3cccnc3c2Cl)no1 InChI=1S/C11H8ClN5O2/c1-6-5-7(16-19-6)14-11(18)9-8(12)10-13-3-2-4-17(10)15-9/h2-5H,1H3,(H,14,16,18) ODSJDGAPXJATKT-UHFFFAOYSA-N 114980 3-chloranyl-N-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::cid_1256890::MLS000538609::3-chloro-N-(5-methyl-3-isoxazolyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide::3-chloro-N-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::SMR000144646::3-chloro-N-(5-methyl-3-isoxazolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::3-chloro-N-(5-methylisoxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114980 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114980&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1256890 252664442 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238856 Cc1nnc(SCC(=O)Nc2nsc(n2)-c2ccc(cc2)C(C)(C)C)s1 InChI=1S/C17H19N5OS3/c1-10-20-21-16(25-10)24-9-13(23)18-15-19-14(26-22-15)11-5-7-12(8-6-11)17(2,3)4/h5-8H,9H2,1-4H3,(H,18,22,23) WJGRHTNRJDYYMY-UHFFFAOYSA-N 114981 N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide::SMR000127561::cid_3527790::N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanamide::MLS000522293::N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114981 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114981&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3527790 252664443 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238857 Clc1ccc(CSc2nc3ccncc3[nH]2)cc1 InChI=1S/C13H10ClN3S/c14-10-3-1-9(2-4-10)8-18-13-16-11-5-6-15-7-12(11)17-13/h1-7H,8H2,(H,16,17) LSMGUBAANPNITB-UHFFFAOYSA-N 49439 SMR000127983::2-[(4-chlorophenyl)methylsulfanyl]-3H-imidazo[4,5-c]pyridine::cid_9551354::2-[(4-chlorophenyl)methylthio]-3H-imidazo[4,5-c]pyridine::MLS000522716::2-[(4-chlorobenzyl)thio]-3H-imidazo[4,5-c]pyridine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49439 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49439&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9551354 252629717 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238858 CC(=Nc1ccccc1)c1sc2ccccc2c1O |w:2.2| InChI=1S/C16H13NOS/c1-11(17-12-7-3-2-4-8-12)16-15(18)13-9-5-6-10-14(13)19-16/h2-10,18H,1H3 OWBIXPDECLROKM-UHFFFAOYSA-N 49454 (2Z)-2-(1-anilinoethylidene)-1-benzothiophen-3-one::(2Z)-2-(1-phenylazanylethylidene)-1-benzothiophen-3-one::SMR000145053::cid_5399972::MLS000550925::2-[1-Phenylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::(2Z)-2-(1-anilinoethylidene)benzothiophen-3-one Oxysterols receptor LXR-beta Homo sapiens 67574 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49454 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49454&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5399972 252629731 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238859 CC(=Nc1cccc(C)c1)c1sc2ccccc2c1O |w:2.2| InChI=1S/C17H15NOS/c1-11-6-5-7-13(10-11)18-12(2)17-16(19)14-8-3-4-9-15(14)20-17/h3-10,19H,1-2H3 WDGGDHCOGSHKMB-UHFFFAOYSA-N 49455 (2Z)-2-[1-(3-methylanilino)ethylidene]-1-benzothiophen-3-one::SMR000145055::cid_6859005::MLS000550927::2-[1-m-Tolylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::(2Z)-2-[1-[(3-methylphenyl)amino]ethylidene]-1-benzothiophen-3-one::(2Z)-2-[1-(m-toluidino)ethylidene]benzothiophen-3-one Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49455 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49455&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6859005 252629732 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238860 CC(C)c1cc([nH]n1)C(=O)NN=C(C)c1cccs1 |w:11.11| InChI=1S/C13H16N4OS/c1-8(2)10-7-11(16-15-10)13(18)17-14-9(3)12-5-4-6-19-12/h4-8H,1-3H3,(H,15,16)(H,17,18) BWBUORCJHAHWOT-UHFFFAOYSA-N 114982 5-Isopropyl-2H-pyrazole-3-carboxylic acid [1-thiophen-2-yl-eth-(Z)-ylidene]-hydrazide::cid_5782679::SMR000147810::5-propan-2-yl-N-[(Z)-1-thiophen-2-ylethylideneamino]-1H-pyrazole-3-carboxamide::MLS000556493::5-isopropyl-N-[(Z)-1-(2-thienyl)ethylideneamino]-1H-pyrazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114982 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114982&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5782679 252664444 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238861 CCOC(=O)c1sc2nc3CC(C)(CC)OCc3cc2c1N InChI=1S/C16H20N2O3S/c1-4-16(3)7-11-9(8-21-16)6-10-12(17)13(15(19)20-5-2)22-14(10)18-11/h6H,4-5,7-8,17H2,1-3H3 OQOQNULQSFFCLL-UHFFFAOYSA-N 49464 MLS000557283::SMR000148200::3-Amino-7-ethyl-7-methyl-7,8-dihydro-5H-pyrano[4,3-b]thieno[3,2-e]pyridine-2-carboxylic acid ethyl ester::cid_3421545 Oxysterols receptor LXR-beta Homo sapiens 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49464 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49464&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3421545 242053132 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238862 Cc1nc(N)sc1N=Nc1ccc(Br)cc1 |w:8.9| InChI=1S/C10H9BrN4S/c1-6-9(16-10(12)13-6)15-14-8-4-2-7(11)3-5-8/h2-5H,1H3,(H2,12,13) CLMHKUIJZLOVDX-UHFFFAOYSA-N 49467 N-[(Z)-(2-azanylidene-4-methyl-1,3-thiazol-5-ylidene)amino]-4-bromanyl-aniline::cid_9551866::SMR000151833::4-bromo-N-[(Z)-(2-imino-4-methyl-5-thiazolylidene)amino]aniline::MLS000564283::4-bromo-N-[(Z)-(2-imino-4-methyl-1,3-thiazol-5-ylidene)amino]aniline::(4-bromophenyl)-[(Z)-(2-imino-4-methyl-3-thiazolin-5-ylidene)amino]amine Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49467 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49467&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9551866 252629743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238863 Cc1cccc(NC(=O)c2ccc3ccccc3n2)c1C InChI=1S/C18H16N2O/c1-12-6-5-9-15(13(12)2)20-18(21)17-11-10-14-7-3-4-8-16(14)19-17/h3-11H,1-2H3,(H,20,21) IBFFDAXZKQDQLD-UHFFFAOYSA-N 49470 N-(2,3-dimethylphenyl)-2-quinolinecarboxamide::SMR000155229::cid_2116521::MLS000569762::N-(2,3-dimethylphenyl)quinoline-2-carboxamide::N-(2,3-dimethylphenyl)quinaldamide Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49470 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49470&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2116521 252629746 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238864 O=C(CCCC(=O)N(CC(=O)NC1CCCC1)C1CCCC1)Nc1ccccn1 InChI=1S/C22H32N4O3/c27-20(25-19-12-5-6-15-23-19)13-7-14-22(29)26(18-10-3-4-11-18)16-21(28)24-17-8-1-2-9-17/h5-6,12,15,17-18H,1-4,7-11,13-14,16H2,(H,24,28)(H,23,25,27) WUNZIMUNMRLMRA-UHFFFAOYSA-N 51792 Pentanedioic acid cyclopentyl-cyclopentylcarbamoylmethyl-amide pyridin-2-ylamide::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-pyridinyl)pentanediamide::cid_650348::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxoethyl]-N-pyridin-2-ylpentanediamide::SMR000004293::MLS000072836::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-pyridin-2-yl-pentanediamide::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2-pyridyl)glutaramide Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51792 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51792&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 650348 252631971 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238865 Nc1nc(Nc2ccc(Cl)cc2)nc2ccccc12 InChI=1S/C14H11ClN4/c15-9-5-7-10(8-6-9)17-14-18-12-4-2-1-3-11(12)13(16)19-14/h1-8H,(H3,16,17,18,19) WXPPDLYBIBDKHZ-UHFFFAOYSA-N 44548 SMR000143487::cid_2953146::N2-(4-chlorophenyl)quinazoline-2,4-diamine;hydrochloride::N~2~-(4-chlorophenyl)-2,4-quinazolinediamine hydrochloride::2-N-(4-chlorophenyl)quinazoline-2,4-diamine;hydrochloride::MLS000536850::(4-aminoquinazolin-2-yl)-(4-chlorophenyl)amine;hydrochloride Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44548 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44548&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 962704 252625159 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238866 Cc1ccc(cc1)S(=O)(=O)NC(=NC(=S)Nc1ccccc1)c1ccccc1 |w:12.13| InChI=1S/C21H19N3O2S2/c1-16-12-14-19(15-13-16)28(25,26)24-20(17-8-4-2-5-9-17)23-21(27)22-18-10-6-3-7-11-18/h2-15H,1H3,(H2,22,23,24,27) KGQQJVZZQBFORJ-UHFFFAOYSA-N 49482 1-[(E)-N-(4-methylphenyl)sulfonyl-C-phenylcarbonimidoyl]-3-phenylthiourea::MLS000570232::1-[(E)-N-(4-methylphenyl)sulfonyl-C-phenyl-carbonimidoyl]-3-phenyl-thiourea::cid_6306769::1-[(E)-(4-methylphenyl)sulfonylimino-phenylmethyl]-3-phenylthiourea::SMR000150341::1-phenyl-3-[(E)-C-phenyl-N-tosyl-carbonimidoyl]thiourea Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49482&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6306769 252629758 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238867 O=c1n(ncc2ccccc12)-c1ccc2ccccc2c1 InChI=1S/C18H12N2O/c21-18-17-8-4-3-7-15(17)12-19-20(18)16-10-9-13-5-1-2-6-14(13)11-16/h1-12H FSLCVBMZDHZDKO-UHFFFAOYSA-N 114983 MLS000565163::2-(2-naphthalenyl)-1-phthalazinone::SMR000152430::2-naphthalen-2-ylphthalazin-1-one::cid_730347::2-(2-naphthyl)phthalazin-1-one Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114983 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114983&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 730347 252664445 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238868 Cc1ccsc1C=NNC(=O)c1sccc1C |w:7.8| InChI=1S/C12H12N2OS2/c1-8-3-5-16-10(8)7-13-14-12(15)11-9(2)4-6-17-11/h3-7H,1-2H3,(H,14,15) ASVULYVVYQJTBX-UHFFFAOYSA-N 114984 3-methyl-N'-[(3-methyl-2-thienyl)methylene]-2-thiophenecarbohydrazide::cid_6873509::SMR000159522::3-methyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]thiophene-2-carboxamide::3-methyl-N-[(E)-(3-methyl-2-thiophenyl)methylideneamino]-2-thiophenecarboxamide::MLS000325445::3-methyl-N-[(E)-(3-methyl-2-thienyl)methyleneamino]thiophene-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114984 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114984&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6873509 252664446 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238869 [O-][N+](=O)c1cccnc1NCCNc1ncc(cc1Cl)C(F)(F)F InChI=1S/C13H11ClF3N5O2/c14-9-6-8(13(15,16)17)7-21-11(9)19-4-5-20-12-10(22(23)24)2-1-3-18-12/h1-3,6-7H,4-5H2,(H,18,20)(H,19,21) ZVZGCHWOUJKNOM-UHFFFAOYSA-N 76427 N'-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-nitro-2-pyridinyl)ethane-1,2-diamine::N~1~-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N~2~-(3-nitro-2-pyridinyl)-1,2-ethanediamine::cid_3773884::SMR000170132::N'-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-nitropyridin-2-yl)ethane-1,2-diamine::MLS000326042::N'-[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]-N-(3-nitropyridin-2-yl)ethane-1,2-diamine::[3-chloro-5-(trifluoromethyl)-2-pyridyl]-[2-[(3-nitro-2-pyridyl)amino]ethyl]amine Oxysterols receptor LXR-beta Homo sapiens 67531 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76427 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76427&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3773884 252653606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238870 FC(F)(F)c1cc(Cl)c2nc(cn2c1)-c1ccccc1 InChI=1S/C14H8ClF3N2/c15-11-6-10(14(16,17)18)7-20-8-12(19-13(11)20)9-4-2-1-3-5-9/h1-8H ATHNSQRFCXRPMB-UHFFFAOYSA-N 49504 MLS000327118::cid_2725829::8-chloranyl-2-phenyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine::SMR000179717::8-chloro-2-phenyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49504&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2725829 252629780 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238871 Cc1cccc(c1)C(N)=NOC(=O)c1cccs1 |w:9.10| InChI=1S/C13H12N2O2S/c1-9-4-2-5-10(8-9)12(14)15-17-13(16)11-6-3-7-18-11/h2-8H,1H3,(H2,14,15) XRPVRHOSGACNPK-UHFFFAOYSA-N 114985 MLS000553241::[(Z)-[azanyl-(3-methylphenyl)methylidene]amino] thiophene-2-carboxylate::2-thiophenecarboxylic acid [(Z)-[amino-(3-methylphenyl)methylidene]amino] ester::SMR000176880::[(Z)-[amino-(3-methylphenyl)methylidene]amino] thiophene-2-carboxylate::cid_9586568::thiophene-2-carboxylic acid [(Z)-[amino(m-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114985 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9586568 252664447 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238872 CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1 InChI=1S/C21H22N4O2S/c1-3-22-21(28)25-24-20(26)17-13-19(23-18-8-6-5-7-16(17)18)14-9-11-15(12-10-14)27-4-2/h5-13H,3-4H2,1-2H3,(H,24,26)(H2,22,25,28) OUMOCZYTTNFGNH-UHFFFAOYSA-N 49511 cid_1767610::1-[[2-(4-ethoxyphenyl)quinoline-4-carbonyl]amino]-3-ethylthiourea::SMR000160210::MLS000545499::1-[[[2-(4-ethoxyphenyl)-4-quinolinyl]-oxomethyl]amino]-3-ethylthiourea::2-{[2-(4-ethoxyphenyl)-4-quinolinyl]carbonyl}-N-ethylhydrazinecarbothioamide::1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]-3-ethyl-thiourea::1-ethyl-3-[(2-p-phenetylquinoline-4-carbonyl)amino]thiourea Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49511 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49511&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1767610 252629787 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238873 C(Cc1ccccc1)Sc1nccn1-c1ccccc1 InChI=1S/C17H16N2S/c1-3-7-15(8-4-1)11-14-20-17-18-12-13-19(17)16-9-5-2-6-10-16/h1-10,12-13H,11,14H2 VARJAHYAMWUYFI-UHFFFAOYSA-N 114986 1-phenyl-2-(2-phenylethylsulfanyl)imidazole::SMR000179805::2-(phenethylsulfanyl)-1-phenyl-1H-imidazole::MLS000327196::cid_1477534::1-phenyl-2-(2-phenylethylthio)imidazole::2-(phenethylthio)-1-phenyl-imidazole::US20240317691, Compound 110 Oxysterols receptor LXR-beta Homo sapiens 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114986 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114986&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1477534 252664448 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238874 Clc1ccc(cc1)-c1ccc(o1)C(=S)N1CCCCC1 InChI=1S/C16H16ClNOS/c17-13-6-4-12(5-7-13)14-8-9-15(19-14)16(20)18-10-2-1-3-11-18/h4-9H,1-3,10-11H2 OBWNESFOIWOSHR-UHFFFAOYSA-N 114987 cid_796821::SMR000193476::1-{[5-(4-chlorophenyl)-2-furyl]carbonothioyl}piperidine::[5-(4-chlorophenyl)furan-2-yl]-piperidin-1-yl-methanethione::[5-(4-chlorophenyl)furan-2-yl]-piperidin-1-ylmethanethione::MLS000571391::[5-(4-chlorophenyl)-2-furanyl]-(1-piperidinyl)methanethione::[5-(4-chlorophenyl)-2-furyl]-piperidino-methanethione Oxysterols receptor LXR-beta Homo sapiens 67497 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114987 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114987&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 796821 252664449 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238875 Nc1c2CCCCCc2nc2sc3CCCCc3c12 InChI=1S/C16H20N2S/c17-15-10-6-2-1-3-8-12(10)18-16-14(15)11-7-4-5-9-13(11)19-16/h1-9H2,(H2,17,18) INQNGSMMHYFCSF-UHFFFAOYSA-N 114988 2,3,4,7,8,9,10,11-octahydro-1H-[1]benzothieno[2,3-b]cyclohepta[e]pyridin-12-amine::MLS000570484::SMR000186910::cid_744115 Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114988 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114988&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 744115 242053908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238876 CCc1ccc(cc1)C1CC(=NN1S(C)(=O)=O)c1ccco1 |c:11| InChI=1S/C16H18N2O3S/c1-3-12-6-8-13(9-7-12)15-11-14(16-5-4-10-21-16)17-18(15)22(2,19)20/h4-10,15H,3,11H2,1-2H3 OAOCQEHAIHFWPC-UHFFFAOYSA-N 114989 3-(4-ethylphenyl)-5-(furan-2-yl)-2-methylsulfonyl-3,4-dihydropyrazole::MLS000580616::SMR000199505::cid_2951757::5-(4-ethylphenyl)-3-(2-furyl)-1-(methylsulfonyl)-4,5-dihydro-1H-pyrazole::3-(4-ethylphenyl)-5-(2-furanyl)-2-methylsulfonyl-3,4-dihydropyrazole::5-(4-ethylphenyl)-3-(2-furyl)-1-mesyl-2-pyrazoline Oxysterols receptor LXR-beta Homo sapiens 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114989 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114989&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2951757 252664450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238877 O=C(NN=Cc1cccs1)c1[nH]nc2CCCc12 |w:3.2| InChI=1S/C12H12N4OS/c17-12(16-13-7-8-3-2-6-18-8)11-9-4-1-5-10(9)14-15-11/h2-3,6-7H,1,4-5H2,(H,14,15)(H,16,17) RHTNOJVNXRSZGT-UHFFFAOYSA-N 114990 N'-(2-thienylmethylene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide::N-[(E)-thiophen-2-ylmethylideneamino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide::SMR000185339::cid_5720643::MLS000576863::N-[(E)-2-thenylideneamino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67519 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114990 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114990&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5720643 252664451 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238878 Cc1ccnc(NC(=O)\C=C\c2cccs2)c1 InChI=1S/C13H12N2OS/c1-10-6-7-14-12(9-10)15-13(16)5-4-11-3-2-8-17-11/h2-9H,1H3,(H,14,15,16) YVGHONIDDFLTOD-UHFFFAOYSA-N 114991 N-(4-methyl-2-pyridinyl)-3-(2-thienyl)acrylamide::(E)-N-(4-methyl-2-pyridinyl)-3-thiophen-2-yl-2-propenamide::(E)-N-(4-methylpyridin-2-yl)-3-thiophen-2-ylprop-2-enamide::cid_845032::SMR000197660::MLS000578251::(E)-N-(4-methylpyridin-2-yl)-3-thiophen-2-yl-prop-2-enamide::(E)-N-(4-methyl-2-pyridyl)-3-(2-thienyl)acrylamide Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114991 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845032 252664452 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238879 Cc1n[nH]c(Nc2cccc(C)c2)c1[N+]([O-])=O InChI=1S/C11H12N4O2/c1-7-4-3-5-9(6-7)12-11-10(15(16)17)8(2)13-14-11/h3-6H,1-2H3,(H2,12,13,14) WTPOMZKVZLWDAL-UHFFFAOYSA-N 43701 (5-Methyl-4-nitro-2H-pyrazol-3-yl)-m-tolyl-amine::SMR000176283::cid_3122354::MLS000569061::5-methyl-N-(3-methylphenyl)-4-nitro-1H-pyrazol-3-amine::(5-methyl-4-nitro-1H-pyrazol-3-yl)-(m-tolyl)amine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43701 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43701&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3122354 252624377 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238880 Cc1c(csc1-c1ccccc1)C(=O)Nc1ccccc1 InChI=1S/C18H15NOS/c1-13-16(18(20)19-15-10-6-3-7-11-15)12-21-17(13)14-8-4-2-5-9-14/h2-12H,1H3,(H,19,20) PRNOOINXYPYYPJ-UHFFFAOYSA-N 76463 4-Methyl-5-phenyl-thiophene-3-carboxylic acid phenylamide::cid_829294::MLS000564604::SMR000177122::4-methyl-N,5-diphenylthiophene-3-carboxamide::4-methyl-N,5-diphenyl-3-thiophenecarboxamide::4-methyl-N,5-diphenyl-thiophene-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67516 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76463 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76463&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 829294 252653641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238881 O=C1\C(Sc2ccc3ccccc3c12)=C/c1cccs1 InChI=1S/C17H10OS2/c18-17-15(10-12-5-3-9-19-12)20-14-8-7-11-4-1-2-6-13(11)16(14)17/h1-10H NYRSOTAWRKGABU-UHFFFAOYSA-N 114852 (2E)-2-(thien-2-ylmethylene)naphtho[2,1-b]thiophen-1(2H)-one::cid_12004806::MLS000584663::SMR000203626::(2E)-2-(thiophen-2-ylmethylidene)-1-benzo[e][1]benzothiolone::(2E)-2-(thiophen-2-ylmethylidene)benzo[e][1]benzothiol-1-one::(2E)-2-(2-thenylidene)benzo[e]benzothiophen-1-one Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114852 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 12004806 252664320 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238882 Cc1ccc(cc1)C(N)=NOC(=O)c1cccs1 |w:9.10| InChI=1S/C13H12N2O2S/c1-9-4-6-10(7-5-9)12(14)15-17-13(16)11-3-2-8-18-11/h2-8H,1H3,(H2,14,15) NRSOGUSQGSRUCP-UHFFFAOYSA-N 114992 MLS000585209::cid_9666663::SMR000203972::2-thiophenecarboxylic acid [(Z)-[amino-(4-methylphenyl)methylidene]amino] ester::4-methyl-N'-[(thien-2-ylcarbonyl)oxy]benzenecarboximidamide::[(Z)-[azanyl-(4-methylphenyl)methylidene]amino] thiophene-2-carboxylate::[(Z)-[amino-(4-methylphenyl)methylidene]amino] thiophene-2-carboxylate::thiophene-2-carboxylic acid [(Z)-[amino(p-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114992 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9666663 252664453 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238883 Cc1cc(O)n(c1O)-c1ccc(NCc2ccc(Cl)cc2)c(c1)[N+]([O-])=O InChI=1S/C18H16ClN3O4/c1-11-8-17(23)21(18(11)24)14-6-7-15(16(9-14)22(25)26)20-10-12-2-4-13(19)5-3-12/h2-9,20,23-24H,10H2,1H3 DVKRIRMDNXYYMV-UHFFFAOYSA-N 83558 1-{4-[(4-chlorobenzyl)amino]-3-nitrophenyl}-3-methylpyrrolidine-2,5-dione::MLS000584616::cid_12005260::1-[4-[(4-chlorophenyl)methylamino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-dione::1-[4-[(4-chlorophenyl)methylamino]-3-nitrophenyl]-3-methylpyrrolidine-2,5-dione::SMR000207201::1-[4-[(4-chlorobenzyl)amino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-quinone Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83558 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83558&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898509 252658745 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238884 N=C1N(CC(=O)c2ccccc2)Cc2ccccc12 InChI=1S/C16H14N2O/c17-16-14-9-5-4-8-13(14)10-18(16)11-15(19)12-6-2-1-3-7-12/h1-9,17H,10-11H2 GMXDICRNXLEYQM-UHFFFAOYSA-N 114993 cid_12005557::SMR000211541::2-(3-imino-1H-isoindol-2-yl)-1-phenylethanone;hydrochloride::MLS000587574::2-(1-Imino-1,3-dihydro-isoindol-2-yl)-1-phenyl-ethanone::2-(3-azanylidene-1H-isoindol-2-yl)-1-phenyl-ethanone;hydrochloride::2-(1-iminoisoindolin-2-yl)-1-phenyl-ethanone;hydrochloride Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114993 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 682597 252664454 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238885 Clc1ccccc1Nc1nnc(s1)-c1ccncc1 InChI=1S/C13H9ClN4S/c14-10-3-1-2-4-11(10)16-13-18-17-12(19-13)9-5-7-15-8-6-9/h1-8H,(H,16,18) KYLJEAUZXBZHNF-UHFFFAOYSA-N 78207 (2-Chloro-phenyl)-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine::N-(2-chlorophenyl)-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine::MLS000331918::cid_1952758::SMR000221404::(2-chlorophenyl)-[5-(4-pyridyl)-1,3,4-thiadiazol-2-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78207&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1952758 252654968 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238886 CC1=CN2C(S1)=NC(=O)\C(=C/c1ccco1)C2=N |c:6,t:1| InChI=1S/C12H9N3O2S/c1-7-6-15-10(13)9(5-8-3-2-4-17-8)11(16)14-12(15)18-7/h2-6,13H,1H3 QNEHKBLPIIBDAT-UHFFFAOYSA-N 49614 (6Z)-6-(2-furanylmethylidene)-5-imino-2-methyl-7-thiazolo[3,2-a]pyrimidinone::(6Z)-6-(furan-2-ylmethylidene)-5-imino-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::(6Z)-5-azanylidene-6-(furan-2-ylmethylidene)-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::MLS000580241::SMR000220510::6-[1-Furan-2-yl-meth-(Z)-ylidene]-5-imino-2-methyl-5,6-dihydro-thiazolo[3,2-a]pyrimidin-7-one::cid_1779857::(6Z)-6-(2-furfurylidene)-5-imino-2-methyl-thiazolo[3,2-a]pyrimidin-7-one Oxysterols receptor LXR-beta Homo sapiens 67489 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49614 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49614&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1779857 252629889 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238887 Cc1ccc(\C=N\NC(=O)c2ccccn2)s1 InChI=1S/C12H11N3OS/c1-9-5-6-10(17-9)8-14-15-12(16)11-4-2-3-7-13-11/h2-8H,1H3,(H,15,16) MMKIBXLZUXTSKE-UHFFFAOYSA-N 114994 SMR000219653::MLS000589024::N-[(E)-(5-methylthiophen-2-yl)methylideneamino]pyridine-2-carboxamide::cid_6878933::N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]-2-pyridinecarboxamide::Pyridine-2-carboxylic acid [1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::N-[(E)-(5-methyl-2-thienyl)methyleneamino]picolinamide Oxysterols receptor LXR-beta Homo sapiens 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114994 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114994&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6878933 252664455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238888 Cc1ccc(\C=N\NC(=O)c2ccoc2C)s1 InChI=1S/C12H12N2O2S/c1-8-3-4-10(17-8)7-13-14-12(15)11-5-6-16-9(11)2/h3-7H,1-2H3,(H,14,15) XVROMXHMMIUPRJ-UHFFFAOYSA-N 114995 SMR000217916::MLS000591098::2-Methyl-furan-3-carboxylic acid [1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::2-methyl-N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]-3-furancarboxamide::2-methyl-N-[(E)-(5-methylthiophen-2-yl)methylideneamino]furan-3-carboxamide::cid_6886797::2-methyl-N-[(E)-(5-methyl-2-thienyl)methyleneamino]-3-furamide Oxysterols receptor LXR-beta Homo sapiens 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114995 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114995&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6886797 252664456 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238889 C(Sc1ccc(nn1)-c1cccs1)c1ccccc1 InChI=1S/C15H12N2S2/c1-2-5-12(6-3-1)11-19-15-9-8-13(16-17-15)14-7-4-10-18-14/h1-10H,11H2 ALXJYDIYDDOWBL-UHFFFAOYSA-N 114996 3-benzylsulfanyl-6-thiophen-2-ylpyridazine::MLS000696686::cid_6624149::SMR000237137::3-(phenylmethylthio)-6-thiophen-2-ylpyridazine::3-(phenylmethylsulfanyl)-6-thiophen-2-yl-pyridazine::3-(benzylthio)-6-(2-thienyl)pyridazine Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114996 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114996&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6624149 252664457 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238890 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)OCC(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C27H27N3O5S2/c1-4-30(5-2)37(33,34)22-13-9-20(10-14-22)27(32)35-17-25(31)28-21-11-7-19(8-12-21)26-29-23-15-6-18(3)16-24(23)36-26/h6-16H,4-5,17H2,1-3H3,(H,28,31) PGGQXUGPYJVIRG-UHFFFAOYSA-N 96095 [2-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]amino]-2-oxidanylidene-ethyl] 4-(diethylsulfamoyl)benzoate::4-(diethylsulfamoyl)benzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester::MLS000395044::cid_2353548::SMR000248410::[2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] 4-(diethylsulfamoyl)benzoate::4-(diethylsulfamoyl)benzoic acid [2-keto-2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]ethyl] ester Oxysterols receptor LXR-beta Homo sapiens 67527 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96095 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2353548 164037339 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238891 COc1ccccc1C=NN=C(N)c1ccccn1 |w:9.10,11.12| InChI=1S/C14H14N4O/c1-19-13-8-3-2-6-11(13)10-17-18-14(15)12-7-4-5-9-16-12/h2-10H,1H3,(H2,15,18) SELWMUSSOZDBSJ-UHFFFAOYSA-N 114997 MLS000698346::N'-(2-methoxybenzylidene)-2-pyridinecarboximidohydrazide::cid_5568682::N'-[(Z)-(2-methoxyphenyl)methylideneamino]pyridine-2-carboximidamide::N'-[(Z)-(2-methoxyphenyl)methylideneamino]-2-pyridinecarboximidamide::SMR000226343::N'-[(Z)-o-anisylideneamino]picolinamidine Oxysterols receptor LXR-beta Homo sapiens 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114997 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114997&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5568682 252664458 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238892 Cc1nn(c(C)c1Br)-c1nnc(NC2CCCCC2)nn1 InChI=1S/C13H18BrN7/c1-8-11(14)9(2)21(20-8)13-18-16-12(17-19-13)15-10-6-4-3-5-7-10/h10H,3-7H2,1-2H3,(H,15,16,17) VIWOUODEFPGMBW-UHFFFAOYSA-N 114998 SMR000225861::6-(4-bromo-3,5-dimethyl-1-pyrazolyl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::cid_5113181::6-(4-bromanyl-3,5-dimethyl-pyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::N-[6-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetraazin-3-yl]-N-cyclohexylamine::MLS000702666::6-(4-bromo-3,5-dimethylpyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::[6-(4-bromo-3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazin-3-yl]-cyclohexyl-amine Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114998 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114998&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5113181 252664459 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238893 Cc1ccc(\C=N\N=C\c2ccc(C)s2)s1 InChI=1S/C12H12N2S2/c1-9-3-5-11(15-9)7-13-14-8-12-6-4-10(2)16-12/h3-8H,1-2H3 QXERRTVWENUEGZ-UHFFFAOYSA-N 114999 cid_6875563::5-methyl-2-thiophenecarbaldehyde [(5-methyl-2-thienyl)methylene]hydrazone::(E)-1-(5-methylthiophen-2-yl)-N-[(E)-(5-methylthiophen-2-yl)methylideneamino]methanimine::SMR000228632::MLS000702008::(E)-1-(5-methyl-2-thiophenyl)-N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]methanimine::(E)-(5-methyl-2-thienyl)methylene-[(E)-(5-methyl-2-thienyl)methyleneamino]amine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114999 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114999&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6875563 252664460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238894 Cc1cc(C(=O)NC2CCCCC2)c(C)n1-c1ccc(F)cc1 InChI=1S/C19H23FN2O/c1-13-12-18(19(23)21-16-6-4-3-5-7-16)14(2)22(13)17-10-8-15(20)9-11-17/h8-12,16H,3-7H2,1-2H3,(H,21,23) GHKAEQQTNJGAAS-UHFFFAOYSA-N 115000 SMR000253346::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethyl-3-pyrrolecarboxamide::cid_3881988::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethylpyrrole-3-carboxamide::MLS000335592::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethyl-pyrrole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115000 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3881988 252664461 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238895 COCCNc1nc(cs1)-c1cc2ccccc2o1 InChI=1S/C14H14N2O2S/c1-17-7-6-15-14-16-11(9-19-14)13-8-10-4-2-3-5-12(10)18-13/h2-5,8-9H,6-7H2,1H3,(H,15,16) AAQZGOOBPBBYOB-UHFFFAOYSA-N 49665 cid_2469776::4-(2-benzofuranyl)-N-(2-methoxyethyl)-2-thiazolamine::4-(1-benzofuran-2-yl)-N-(2-methoxyethyl)-1,3-thiazol-2-amine::MLS000388876::SMR000255049::[4-(benzofuran-2-yl)thiazol-2-yl]-(2-methoxyethyl)amine Oxysterols receptor LXR-beta Homo sapiens 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49665 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49665&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2469776 252629940 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238896 Fc1ccccc1SCn1nnc2ccccc2c1=O InChI=1S/C14H10FN3OS/c15-11-6-2-4-8-13(11)20-9-18-14(19)10-5-1-3-7-12(10)16-17-18/h1-8H,9H2 VVFGFLFZBRPQFD-UHFFFAOYSA-N 115001 3-[(2-fluorophenyl)sulfanylmethyl]-1,2,3-benzotriazin-4-one::SMR000255075::MLS000388902::cid_2591914::3-[[(2-fluorophenyl)thio]methyl]-1,2,3-benzotriazin-4-one Oxysterols receptor LXR-beta Homo sapiens 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115001 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115001&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2591914 252664462 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238897 N(N=Cc1ccccc1)C1=Nc2cccc3cccc1c23 |w:1.0,t:10| InChI=1S/C18H13N3/c1-2-6-13(7-3-1)12-19-21-18-15-10-4-8-14-9-5-11-16(20-18)17(14)15/h1-12H,(H,20,21) BHVRGHUCIOBZDB-UHFFFAOYSA-N 51101 cid_2315076::MLS000392783::N-[(phenylmethylidene)amino]benzo[cd]indol-2-amine::N-[(phenylmethylene)amino]-2-benzo[cd]indolamine::N-(benzylideneamino)benzo[cd]indol-2-amine::SMR000261715::[(E)-benzalamino]-benzo[cd]indol-2-yl-amine::(benzalamino)-benzo[cd]indol-2-yl-amine Oxysterols receptor LXR-beta Homo sapiens 67540 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51101 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899626 252631337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238898 Cc1nn(c(Cl)c1CN=Nc1ccc(Cl)c(c1)C(O)=O)-c1ccccc1 |w:9.10| InChI=1S/C18H14Cl2N4O2/c1-11-15(17(20)24(23-11)13-5-3-2-4-6-13)10-21-22-12-7-8-16(19)14(9-12)18(25)26/h2-9H,10H2,1H3,(H,25,26) AVPQBTDFOVKKJX-UHFFFAOYSA-N 49680 2-chloro-5-[2-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methylidene]hydrazinyl]benzoic acid::MLS000417411::SMR000242629::2-chloro-5-[(N''E)-N''-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid::2-chloranyl-5-[2-[(5-chloranyl-3-methyl-1-phenyl-pyrazol-4-yl)methylidene]hydrazinyl]benzoic acid::cid_4321955::2-chloro-5-[2-[(5-chloro-3-methyl-1-phenyl-4-pyrazolyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[(N'E)-N'-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid::2-chloro-5-[N'-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid Oxysterols receptor LXR-beta Homo sapiens 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49680 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49680&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896831 252629955 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238899 [O-][N+](=O)c1n[nH]c(C(=O)Nc2ccn(Cc3ccccc3)n2)c1Cl InChI=1S/C14H11ClN6O3/c15-11-12(17-18-13(11)21(23)24)14(22)16-10-6-7-20(19-10)8-9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18)(H,16,19,22) JMTYOGKXLZBBGH-UHFFFAOYSA-N 72350 MLS000698607::4-chloranyl-3-nitro-N-[1-(phenylmethyl)pyrazol-3-yl]-1H-pyrazole-5-carboxamide::SMR000228119::4-chloro-3-nitro-N-[1-(phenylmethyl)-3-pyrazolyl]-1H-pyrazole-5-carboxamide::N-(1-benzyl-1H-pyrazol-3-yl)-4-chloro-5-nitro-1H-pyrazole-3-carboxamide::cid_843505::N-(1-benzylpyrazol-3-yl)-4-chloro-3-nitro-1H-pyrazole-5-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72350&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 843505 252649612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238900 Cc1cccc(C=Cc2nc3ccccc3c(=O)[nH]2)c1 |w:7.7| InChI=1S/C17H14N2O/c1-12-5-4-6-13(11-12)9-10-16-18-15-8-3-2-7-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20) BLVJYZMMPDHHHO-UHFFFAOYSA-N 49809 SMR000277632::2-[(E)-2-(3-methylphenyl)ethenyl]-1H-quinazolin-4-one::cid_5768144::MLS000716115::2-[(Z)-2-(m-tolyl)vinyl]-1H-quinazolin-4-one::2-[(E)-2-(m-tolyl)vinyl]-1H-quinazolin-4-one Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49809 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49809&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5768144 252630084 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238901 Cc1ccn(n1)-c1cccc(n1)-n1ccc(C)n1 InChI=1S/C13H13N5/c1-10-6-8-17(15-10)12-4-3-5-13(14-12)18-9-7-11(2)16-18/h3-9H,1-2H3 RAIXXDUNEZBGDR-UHFFFAOYSA-N 115003 cid_850137::2,6-bis(3-methyl-1H-pyrazol-1-yl)pyridine::SMR000229839::MLS000702817::2,6-bis(3-methyl-1-pyrazolyl)pyridine::2,6-bis(3-methylpyrazol-1-yl)pyridine Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115003 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115003&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 850137 252664463 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238902 Nc1ncc(Br)cc1\N=C\c1ccccc1 InChI=1S/C12H10BrN3/c13-10-6-11(12(14)16-8-10)15-7-9-4-2-1-3-5-9/h1-8H,(H2,14,16) OZFHWELCBWFVEW-UHFFFAOYSA-N 115004 SMR000229236::MLS000706620::5-bromo-3-[(phenylmethylene)amino]-2-pyridinamine::N-(2-amino-5-bromo-3-pyridinyl)-N-benzylideneamine::cid_838785::3-(benzylideneamino)-5-bromopyridin-2-amine::5-bromanyl-3-[(phenylmethylidene)amino]pyridin-2-amine::[3-(benzalamino)-5-bromo-2-pyridyl]amine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115004 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115004&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 838785 252664464 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238903 CCC(=NNC(=O)c1ccoc1C)c1ccc(C)o1 |w:3.3| InChI=1S/C14H16N2O3/c1-4-12(13-6-5-9(2)19-13)15-16-14(17)11-7-8-18-10(11)3/h5-8H,4H2,1-3H3,(H,16,17) YWMGQDPNMYSSLK-UHFFFAOYSA-N 115005 2-methyl-N-[(E)-1-(5-methylfuran-2-yl)propylideneamino]furan-3-carboxamide::SMR000227970::2-methyl-N'-[1-(5-methyl-2-furyl)propylidene]-3-furohydrazide::2-methyl-N-[(E)-1-(5-methyl-2-furanyl)propylideneamino]-3-furancarboxamide::MLS000698059::cid_5842394::2-methyl-N-[(E)-1-(5-methyl-2-furyl)propylideneamino]-3-furamide Oxysterols receptor LXR-beta Homo sapiens 67491 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115005 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115005&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5842394 252664465 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238904 Cc1scc(C(=O)N\N=C\c2ccsc2)c1C InChI=1S/C12H12N2OS2/c1-8-9(2)17-7-11(8)12(15)14-13-5-10-3-4-16-6-10/h3-7H,1-2H3,(H,14,15) SEFLPDGXFQMXCS-UHFFFAOYSA-N 115006 4,5-dimethyl-N-[(E)-thiophen-3-ylmethylideneamino]thiophene-3-carboxamide::MLS000699345::4,5-dimethyl-N-[(E)-3-thiophenylmethylideneamino]-3-thiophenecarboxamide::SMR000227975::cid_6875163::4,5-dimethyl-N'-(3-thienylmethylene)-3-thiophenecarbohydrazide::4,5-dimethyl-N-[(E)-3-thenylideneamino]thiophene-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115006 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115006&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6875163 252664466 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238905 Cc1ccc(Nc2ncccc2C(N)=O)cc1 InChI=1S/C13H13N3O/c1-9-4-6-10(7-5-9)16-13-11(12(14)17)3-2-8-15-13/h2-8H,1H3,(H2,14,17)(H,15,16) QSBJMVSZUKBBIL-UHFFFAOYSA-N 75495 MLS000700317::2-(4-methylanilino)-3-pyridinecarboxamide::2-(4-methylanilino)pyridine-3-carboxamide::2-(4-toluidino)nicotinamide::SMR000226873::cid_901941::2-[(4-methylphenyl)amino]pyridine-3-carboxamide::2-(p-toluidino)nicotinamide Oxysterols receptor LXR-beta Homo sapiens 67441 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75495&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 901941 252652702 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238906 Cc1ccc(Nc2ncccc2C(N)=O)cc1[N+]([O-])=O InChI=1S/C13H12N4O3/c1-8-4-5-9(7-11(8)17(19)20)16-13-10(12(14)18)3-2-6-15-13/h2-7H,1H3,(H2,14,18)(H,15,16) OSBQBRNMQSMSFD-UHFFFAOYSA-N 115007 2-{3-nitro-4-methylanilino}nicotinamide::cid_901926::2-[(4-methyl-3-nitro-phenyl)amino]pyridine-3-carboxamide::MLS000700314::SMR000226870::2-(4-methyl-3-nitroanilino)pyridine-3-carboxamide::2-(4-methyl-3-nitroanilino)-3-pyridinecarboxamide::2-(4-methyl-3-nitro-anilino)nicotinamide Oxysterols receptor LXR-beta Homo sapiens 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115007 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115007&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 901926 252664467 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238907 O=C(\C=C\c1ccccc1)N1CCC(C1)c1ccccc1 InChI=1S/C19H19NO/c21-19(12-11-16-7-3-1-4-8-16)20-14-13-18(15-20)17-9-5-2-6-10-17/h1-12,18H,13-15H2 FKRPYXCRUAIJQQ-UHFFFAOYSA-N 115008 1-cinnamoyl-3-phenylpyrrolidine::SMR000268864::cid_5729968::(E)-3-phenyl-1-(3-phenylpyrrolidin-1-yl)prop-2-en-1-one::(E)-3-phenyl-1-(3-phenyl-1-pyrrolidinyl)-2-propen-1-one::MLS000666535::(E)-3-phenyl-1-(3-phenylpyrrolidino)prop-2-en-1-one Oxysterols receptor LXR-beta Homo sapiens 67522 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115008 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115008&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5729968 252664468 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238908 Fc1ccc(cc1)-n1nnc(n1)-c1cccnc1Cl InChI=1S/C12H7ClFN5/c13-11-10(2-1-7-15-11)12-16-18-19(17-12)9-5-3-8(14)4-6-9/h1-7H FJEQSNOGJXPASP-UHFFFAOYSA-N 49719 MLS000697778::2-chloro-3-[2-(4-fluorophenyl)-5-tetrazolyl]pyridine::2-chloro-3-(2-(4-fluorophenyl)-2H-tetrazol-5-yl)pyridine::SMR000327356::2-chloranyl-3-[2-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]pyridine::cid_16066526::2-chloro-3-[2-(4-fluorophenyl)tetrazol-5-yl]pyridine Oxysterols receptor LXR-beta Homo sapiens 67479 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49719 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16066526 252629994 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238909 Cc1cc(ccc1NS(=O)(=O)c1cccs1)-c1nc2cccnc2s1 InChI=1S/C17H13N3O2S3/c1-11-10-12(16-19-14-4-2-8-18-17(14)24-16)6-7-13(11)20-25(21,22)15-5-3-9-23-15/h2-10,20H,1H3 WZNVRQOYBMQWKT-UHFFFAOYSA-N 115009 cid_16187060::N-[2-methyl-4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]thiophene-2-sulfonamide::SMR000127210::MLS000529674::N-[2-methyl-4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-thiophenesulfonamide::N-(2-methyl-4-thiazolo[5,4-b]pyridin-2-yl-phenyl)thiophene-2-sulfonamide Oxysterols receptor LXR-beta Homo sapiens 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115009 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115009&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16187060 252664469 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238910 CCn1c(O)c(C=Nc2ccccc2)sc1=S |w:7.7| InChI=1S/C12H12N2OS2/c1-2-14-11(15)10(17-12(14)16)8-13-9-6-4-3-5-7-9/h3-8,15H,2H2,1H3 ZMUTZNCDEDSUFW-UHFFFAOYSA-N 74916 SMR000280182::(5Z)-5-(anilinomethylidene)-3-ethyl-2-sulfanylidene-4-thiazolidinone::(5Z)-3-ethyl-5-(phenylazanylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one::MLS000710415::cid_5373057::(5Z)-5-(anilinomethylidene)-3-ethyl-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-5-(anilinomethylene)-3-ethyl-2-thioxo-thiazolidin-4-one Oxysterols receptor LXR-beta Homo sapiens 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=74916 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=74916&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5373057 252652134 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238911 CC(N(C)C(=O)CCc1nnc(CCC2CCCCC2)o1)c1cccs1 InChI=1S/C20H29N3O2S/c1-15(17-9-6-14-26-17)23(2)20(24)13-12-19-22-21-18(25-19)11-10-16-7-4-3-5-8-16/h6,9,14-16H,3-5,7-8,10-13H2,1-2H3 RQEUFHOJAPAUCA-UHFFFAOYSA-N 115010 3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(2-thienyl)ethyl]propanamide::SMR000318996::cid_16188383::3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-(1-thiophen-2-ylethyl)propanamide::MLS000731697::3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(2-thienyl)ethyl]propionamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115010 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188383 252664470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238912 COCC1CCN(Cc2nc(no2)-c2cccs2)C1 InChI=1S/C13H17N3O2S/c1-17-9-10-4-5-16(7-10)8-12-14-13(15-18-12)11-3-2-6-19-11/h2-3,6,10H,4-5,7-9H2,1H3 WVYAQXZPLIQQEL-UHFFFAOYSA-N 115011 SMR000317964::MLS000733629::cid_16188699::5-[[3-(methoxymethyl)pyrrolidin-1-yl]methyl]-3-thiophen-2-yl-1,2,4-oxadiazole::5-[[3-(methoxymethyl)-1-pyrrolidinyl]methyl]-3-thiophen-2-yl-1,2,4-oxadiazole::5-{[3-(methoxymethyl)pyrrolidin-1-yl]methyl}-3-(2-thienyl)-1,2,4-oxadiazole::5-[[3-(methoxymethyl)pyrrolidino]methyl]-3-(2-thienyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67513 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115011 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188699 252664471 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238913 O=C(NCCCn1ccnc1)c1cc(on1)-c1ccccc1 InChI=1S/C16H16N4O2/c21-16(18-7-4-9-20-10-8-17-12-20)14-11-15(22-19-14)13-5-2-1-3-6-13/h1-3,5-6,8,10-12H,4,7,9H2,(H,18,21) FLWZIODGHJAZJD-UHFFFAOYSA-N 49766 N-[3-(1-imidazolyl)propyl]-5-phenyl-3-isoxazolecarboxamide::N-(3-imidazol-1-ylpropyl)-5-phenyl-1,2-oxazole-3-carboxamide::SMR000289715::cid_2962284::MLS000708948::N-(3-imidazol-1-ylpropyl)-5-phenyl-isoxazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67534 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49766 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2962284 252630041 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238914 Cc1ccc2oc(nc2c1)-c1cccc(N)c1 InChI=1S/C14H12N2O/c1-9-5-6-13-12(7-9)16-14(17-13)10-3-2-4-11(15)8-10/h2-8H,15H2,1H3 YGMVUJGLTNKWJJ-UHFFFAOYSA-N 49767 3-(5-methyl-1,3-benzoxazol-2-yl)aniline::MLS000710395::SMR000280162::cid_348698::[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]amine Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49767 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 348698 252630042 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238915 COCCNC(=O)C(=C\c1cc(C)n(c1C)-c1ccc(C)cc1)\C#N InChI=1S/C20H23N3O2/c1-14-5-7-19(8-6-14)23-15(2)11-17(16(23)3)12-18(13-21)20(24)22-9-10-25-4/h5-8,11-12H,9-10H2,1-4H3,(H,22,24) JHMGNUKCJAFHQI-UHFFFAOYSA-N 49768 (E)-2-cyano-3-[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]-N-(2-methoxyethyl)-2-propenamide::MLS000711883::SMR000281650::cid_5766269::(E)-2-cyano-3-[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]-N-(2-methoxyethyl)prop-2-enamide::(E)-2-cyano-3-[2,5-dimethyl-1-(p-tolyl)pyrrol-3-yl]-N-(2-methoxyethyl)acrylamide Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49768 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5766269 252630043 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238916 Clc1ccc(OCCSc2ncccn2)c(Br)c1 InChI=1S/C12H10BrClN2OS/c13-10-8-9(14)2-3-11(10)17-6-7-18-12-15-4-1-5-16-12/h1-5,8H,6-7H2 MSVBXLUEPIYGMR-UHFFFAOYSA-N 93816 2-[2-(2-bromo-4-chlorophenoxy)ethylthio]pyrimidine::2-[2-(2-bromanyl-4-chloranyl-phenoxy)ethylsulfanyl]pyrimidine::cid_2199876::2-{[2-(2-bromo-4-chlorophenoxy)ethyl]thio}pyrimidine::SMR000293424::MLS000675409::2-[2-(2-bromo-4-chlorophenoxy)ethylsulfanyl]pyrimidine::2-[2-(2-bromo-4-chloro-phenoxy)ethylthio]pyrimidine Oxysterols receptor LXR-beta Homo sapiens 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93816 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2199876 164035060 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238917 COc1cccc(c1)-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C13H9BrN2O3/c1-17-9-4-2-3-8(7-9)13-15-12(16-19-13)10-5-6-11(14)18-10/h2-7H,1H3 UXGUULAJPLEVKH-UHFFFAOYSA-N 115012 3-(5-bromo-2-furanyl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::MLS000674412::SMR000297369::cid_717858::3-(5-bromanylfuran-2-yl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67493 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115012 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717858 252664472 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238918 Brc1ccc(o1)-c1noc(n1)-c1ccccc1 InChI=1S/C12H7BrN2O2/c13-10-7-6-9(16-10)11-14-12(17-15-11)8-4-2-1-3-5-8/h1-7H MFTLYVBFNAAAHY-UHFFFAOYSA-N 115013 SMR000297412::MLS000674457::cid_5150753::3-(5-bromo-2-furanyl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromanylfuran-2-yl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-phenyl-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115013 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5150753 252664473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238919 NC(=NOC(=O)c1cc(Br)ccc1Cl)c1ccccn1 |w:2.2| InChI=1S/C13H9BrClN3O2/c14-8-4-5-10(15)9(7-8)13(19)20-18-12(16)11-3-1-2-6-17-11/h1-7H,(H2,16,18) CGXGAXMMGDPJML-UHFFFAOYSA-N 49794 N'-[(5-bromo-2-chlorobenzoyl)oxy]-2-pyridinecarboximidamide::SMR000293913::[(Z)-[azanyl(pyridin-2-yl)methylidene]amino] 5-bromanyl-2-chloranyl-benzoate::5-bromo-2-chlorobenzoic acid [(Z)-[amino(2-pyridinyl)methylidene]amino] ester::MLS000625126::[(Z)-[amino(pyridin-2-yl)methylidene]amino] 5-bromo-2-chlorobenzoate::cid_9587775::5-bromo-2-chloro-benzoic acid [(Z)-[amino(2-pyridyl)methylene]amino] ester Oxysterols receptor LXR-beta Homo sapiens 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49794 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9587775 252630069 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238920 Cc1ccc(cc1)-c1csc(NC(=O)\C=C\c2ccco2)c1C(O)=O InChI=1S/C19H15NO4S/c1-12-4-6-13(7-5-12)15-11-25-18(17(15)19(22)23)20-16(21)9-8-14-3-2-10-24-14/h2-11H,1H3,(H,20,21)(H,22,23) VMPSOGVIMUYKTH-UHFFFAOYSA-N 115014 SMR000297919::2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-4-(4-methylphenyl)thiophene-3-carboxylic acid::cid_1206157::MLS000673879::2-{[3-(2-furyl)acryloyl]amino}-4-(4-methylphenyl)-3-thiophenecarboxylic acid::2-[[(E)-3-(2-furanyl)-1-oxoprop-2-enyl]amino]-4-(4-methylphenyl)-3-thiophenecarboxylic acid::2-[[(E)-3-(2-furyl)acryloyl]amino]-4-(p-tolyl)-3-thenoic acid Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115014 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1206157 252664474 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238921 CC(C)CN1CCN(Cc2ccc(C)s2)CC1CCO InChI=1S/C16H28N2OS/c1-13(2)10-18-8-7-17(11-15(18)6-9-19)12-16-5-4-14(3)20-16/h4-5,13,15,19H,6-12H2,1-3H3 ZEMAHOYXOAHHGN-UHFFFAOYSA-N 72483 2-[1-(2-methylpropyl)-4-[(5-methylthiophen-2-yl)methyl]piperazin-2-yl]ethanol::2-{1-isobutyl-4-[(5-methyl-2-thienyl)methyl]piperazin-2-yl}ethanol::SMR000317233::cid_16191481::2-[1-(2-methylpropyl)-4-[(5-methyl-2-thiophenyl)methyl]-2-piperazinyl]ethanol::MLS000734180::2-[1-isobutyl-4-[(5-methyl-2-thienyl)methyl]piperazin-2-yl]ethanol Oxysterols receptor LXR-beta Homo sapiens 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72483&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16191481 252649743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238922 CN1C(=O)\C(=N/NC(=O)c2ccco2)c2ccccc12 InChI=1S/C14H11N3O3/c1-17-10-6-3-2-5-9(10)12(14(17)19)15-16-13(18)11-7-4-8-20-11/h2-8H,1H3,(H,16,18) OABKHWMTAHJLEU-UHFFFAOYSA-N 115015 N-[(Z)-(1-methyl-2-oxoindol-3-ylidene)amino]furan-2-carboxamide::SMR000277793::cid_5720547::N-[(Z)-(1-methyl-2-oxidanylidene-indol-3-ylidene)amino]furan-2-carboxamide::MLS000716276::N-[(Z)-(1-methyl-2-oxo-3-indolylidene)amino]-2-furancarboxamide::N-[(Z)-(2-keto-1-methyl-indolin-3-ylidene)amino]-2-furamide Oxysterols receptor LXR-beta Homo sapiens 67471 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115015 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5720547 252664475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238923 O=C(Nc1ccccn1)c1csc2CCCCc12 InChI=1S/C14H14N2OS/c17-14(16-13-7-3-4-8-15-13)11-9-18-12-6-2-1-5-10(11)12/h3-4,7-9H,1-2,5-6H2,(H,15,16,17) UCQAMKMTOLXIEF-UHFFFAOYSA-N 115016 MLS000711438::cid_829296::SMR000281205::N-pyridin-2-yl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::N-(2-pyridinyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::N-(2-pyridyl)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115016 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 829296 252664476 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238924 COC1=C\C(=C\c2c(N)n3nc(sc3nc2=O)-c2ccc(C)cc2)C=CC1=O |c:27,t:2| InChI=1S/C20H16N4O3S/c1-11-3-6-13(7-4-11)19-23-24-17(21)14(18(26)22-20(24)28-19)9-12-5-8-15(25)16(10-12)27-2/h3-10H,21H2,1-2H3 GBAMFVYOEZXVMB-UHFFFAOYSA-N 50476 5-amino-6-[(E)-(3-methoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::6-(4-hydroxy-3-methoxybenzylidene)-5-imino-2-(4-methylphenyl)-5,6-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::5-azanyl-6-[(E)-(3-methoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::cid_5874617::5-amino-6-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::SMR000298487::MLS000676609::5-amino-6-[(E)-(4-keto-3-methoxy-cyclohexa-2,5-dien-1-ylidene)methyl]-2-(p-tolyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one Oxysterols receptor LXR-beta Homo sapiens 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5874617 252630736 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238925 OC(=O)c1cc(n[nH]1)-c1cccs1 InChI=1S/C8H6N2O2S/c11-8(12)6-4-5(9-10-6)7-2-1-3-13-7/h1-4H,(H,9,10)(H,11,12) DUDBNCNNJMOLCC-UHFFFAOYSA-N 115017 SMR000278045::MLS000716528::cid_818268::5-thiophen-2-yl-1H-pyrazole-3-carboxylic acid::5-(2-thienyl)-1H-pyrazole-3-carboxylic acid Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115017 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 818268 252664477 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238926 COC(=O)c1sc2nc3CCCCc3cc2c1N InChI=1S/C13H14N2O2S/c1-17-13(16)11-10(14)8-6-7-4-2-3-5-9(7)15-12(8)18-11/h6H,2-5,14H2,1H3 GVZNNNWVSDWYFO-UHFFFAOYSA-N 49828 SMR000287948::methyl 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate::MLS000708481::cid_2838748::methyl 3-azanyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate::3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid methyl ester Oxysterols receptor LXR-beta Homo sapiens 67510 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49828 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49828&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2838748 252630103 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238927 CCCSc1nsc(NC(=O)CC)n1 InChI=1S/C8H13N3OS2/c1-3-5-13-8-10-7(14-11-8)9-6(12)4-2/h3-5H2,1-2H3,(H,9,10,11,12) XHBGDQMFERCBGL-UHFFFAOYSA-N 115018 N-(3-propylsulfanyl-1,2,4-thiadiazol-5-yl)propanamide::SMR000278527::MLS000717160::N-[3-(propylthio)-1,2,4-thiadiazol-5-yl]propanamide::cid_3128534::N-[3-(propylthio)-1,2,4-thiadiazol-5-yl]propionamide Oxysterols receptor LXR-beta Homo sapiens 67531 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3128534 252664478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238928 Cc1ccc(cc1)-c1cn2cccnc2n1 InChI=1S/C13H11N3/c1-10-3-5-11(6-4-10)12-9-16-8-2-7-14-13(16)15-12/h2-9H,1H3 FXPRTYODRQWLLM-UHFFFAOYSA-N 115019 MLS000707292::SMR000288757::cid_727295::2-(4-methylphenyl)imidazo[1,2-a]pyrimidine::2-(p-tolyl)imidazo[1,2-a]pyrimidine Oxysterols receptor LXR-beta Homo sapiens 67635 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115019 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 727295 252664479 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238929 O=C(Nc1ccccn1)C(=O)Nc1ccccn1 InChI=1S/C12H10N4O2/c17-11(15-9-5-1-3-7-13-9)12(18)16-10-6-2-4-8-14-10/h1-8H,(H,13,15,17)(H,14,16,18) AEGDXMYEDPEYCG-UHFFFAOYSA-N 69226 N,N'-dipyridin-2-ylethanediamide::SMR000279742::N,N'-dipyridin-2-yloxamide::MLS000766036::N,N'-bis(2-pyridinyl)oxamide::cid_1927420::N,N'-bis(2-pyridyl)oxamide Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69226&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1927420 252647394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238930 COCCNC(=O)C(=C\c1cc(C)n(C2CCCCC2)c1C)\C#N InChI=1S/C19H27N3O2/c1-14-11-16(12-17(13-20)19(23)21-9-10-24-3)15(2)22(14)18-7-5-4-6-8-18/h11-12,18H,4-10H2,1-3H3,(H,21,23) WHVBXRMNFAHENC-UHFFFAOYSA-N 115020 (E)-2-cyano-3-(1-cyclohexyl-2,5-dimethylpyrrol-3-yl)-N-(2-methoxyethyl)prop-2-enamide::MLS000710555::cid_5766786::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-3-pyrrolyl)-N-(2-methoxyethyl)-2-propenamide::SMR000280322::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-pyrrol-3-yl)-N-(2-methoxyethyl)prop-2-enamide::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-pyrrol-3-yl)-N-(2-methoxyethyl)acrylamide Oxysterols receptor LXR-beta Homo sapiens 67509 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115020 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5766786 252664480 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238931 CN1CCS\C1=C/C=C1\N(C)C(=S)N(C)C1=O InChI=1S/C11H15N3OS2/c1-12-6-7-17-9(12)5-4-8-10(15)14(3)11(16)13(8)2/h4-5H,6-7H2,1-3H3 FVFBOOXTOBVBGN-UHFFFAOYSA-N 115021 (5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-2-sulfanylideneimidazolidin-4-one::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-2-thiazolidinylidene)ethylidene]-2-sulfanylidene-4-imidazolidinone::MLS000724094::cid_5568081::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-2-sulfanylidene-imidazolidin-4-one::1,3-Dimethyl-5-[2-(3-methyl-thiazolidin-2-ylidene)-ethylidene]-2-thioxo-imidazol::SMR000305689::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methylthiazolidin-2-ylidene)ethylidene]-2-thioxo-4-imidazolidinone Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115021&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5568081 252664481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238932 Cc1ccc(NN=C(C#N)C(=N)N2CCCCCC2)cc1 |w:6.5| InChI=1S/C16H21N5/c1-13-6-8-14(9-7-13)19-20-15(12-17)16(18)21-10-4-2-3-5-11-21/h6-9,18-19H,2-5,10-11H2,1H3 QYMPACHMHMQLTD-UHFFFAOYSA-N 49867 SMR000306829::3-azanylidene-3-(azepan-1-yl)-2-[(4-methylphenyl)hydrazinylidene]propanenitrile::MLS000728136::(2E)-3-(azepan-1-yl)-3-imino-2-(p-tolylhydrazono)propionitrile::cid_6805932::3-(1-azepanyl)-3-imino-2-[(4-methylphenyl)hydrazinylidene]propanenitrile::2-(azepan-1-yl)-2-imino-N-(4-methylanilino)ethanimidoyl cyanide::(2E)-3-azepan-1-yl-3-imino-2-[(4-methylphenyl)hydrazono]propanenitrile::3-(azepan-1-yl)-3-imino-2-(p-tolylhydrazono)propionitrile Oxysterols receptor LXR-beta Homo sapiens 67466 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49867 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6401033 252630142 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238933 C(Sc1ccc(nn1)-c1ccccn1)c1ccccn1 InChI=1S/C15H12N4S/c1-3-9-16-12(5-1)11-20-15-8-7-14(18-19-15)13-6-2-4-10-17-13/h1-10H,11H2 BMHGUWQJWGVXMD-UHFFFAOYSA-N 115023 SMR000323987::cid_7162438::MLS000678515::3-pyridin-2-yl-6-(pyridin-2-ylmethylsulfanyl)pyridazine::3-(2-pyridinyl)-6-(2-pyridinylmethylthio)pyridazine::3-(2-pyridyl)-6-(2-pyridylmethylthio)pyridazine Oxysterols receptor LXR-beta Homo sapiens 67475 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115023 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7162438 252664482 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238934 COc1ccc(Oc2cnn(-c3ccccc3)c(=O)c2Br)cc1 InChI=1S/C17H13BrN2O3/c1-22-13-7-9-14(10-8-13)23-15-11-19-20(17(21)16(15)18)12-5-3-2-4-6-12/h2-11H,1H3 QWURXOMVQVPBSF-UHFFFAOYSA-N 115024 4-bromo-5-(4-methoxyphenoxy)-2-phenylpyridazin-3-one::SMR000336319::cid_1480667::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-3-pyridazinone::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-3(2H)-pyridazinone::MLS000720559::4-bromanyl-5-(4-methoxyphenoxy)-2-phenyl-pyridazin-3-one::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-pyridazin-3-one Oxysterols receptor LXR-beta Homo sapiens 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1480667 252664483 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238935 Nc1nn(cc1-c1ccccc1)-c1cccc(F)n1 InChI=1S/C14H11FN4/c15-12-7-4-8-13(17-12)19-9-11(14(16)18-19)10-5-2-1-3-6-10/h1-9H,(H2,16,18) XHTYRUFTVZVORB-UHFFFAOYSA-N 49904 1-(6-fluoro-2-pyridinyl)-4-phenyl-1H-pyrazol-3-amine::1-(6-fluoropyridin-2-yl)-4-phenylpyrazol-3-amine::1-(6-fluoranylpyridin-2-yl)-4-phenyl-pyrazol-3-amine::cid_1478415::MLS000694607::1-(6-fluoro-2-pyridinyl)-4-phenyl-3-pyrazolamine::SMR000333273::[1-(6-fluoro-2-pyridyl)-4-phenyl-pyrazol-3-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67459 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49904 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1478415 252630178 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238936 CN(C)C(C)=CC(=O)c1sccc1Cl |w:5.5| InChI=1S/C10H12ClNOS/c1-7(12(2)3)6-9(13)10-8(11)4-5-14-10/h4-6H,1-3H3 OTCHHTIPXGJWQX-UHFFFAOYSA-N 115025 cid_5525417::(E)-1-(3-chloro-2-thienyl)-3-(dimethylamino)-2-buten-1-one::SMR000336368::(E)-1-(3-chloranylthiophen-2-yl)-3-(dimethylamino)but-2-en-1-one::(E)-1-(3-chloro-2-thiophenyl)-3-(dimethylamino)-2-buten-1-one::MLS000720628::(E)-1-(3-chlorothiophen-2-yl)-3-(dimethylamino)but-2-en-1-one::(E)-1-(3-chloro-2-thienyl)-3-(dimethylamino)but-2-en-1-one Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115025 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5525417 252664484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238937 CN(C)C=NC(=S)Nc1ccc(Cl)cc1 |w:4.4| InChI=1S/C10H12ClN3S/c1-14(2)7-12-10(15)13-9-5-3-8(11)4-6-9/h3-7H,1-2H3,(H,13,15) RHZZAPBYVAKUFY-UHFFFAOYSA-N 115026 SMR000333173::cid_9581725::N-(4-chlorophenyl)-N'-[(dimethylamino)methylene]thiourea::(3E)-1-(4-chlorophenyl)-3-(dimethylaminomethylidene)thiourea::MLS000694855::(3E)-1-(4-chlorophenyl)-3-(dimethylaminomethylene)thiourea Oxysterols receptor LXR-beta Homo sapiens 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115026 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115026&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9581725 252664485 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238938 C(N=C1Nc2ccccc2CS1)c1ccccn1 |w:1.0| InChI=1S/C14H13N3S/c1-2-7-13-11(5-1)10-18-14(17-13)16-9-12-6-3-4-8-15-12/h1-8H,9-10H2,(H,16,17) XNMRPWZYTMZSDO-UHFFFAOYSA-N 115027 N-(2-pyridinylmethyl)-4H-3,1-benzothiazin-2-amine::SMR000333326::cid_3838280::N-(pyridin-2-ylmethyl)-4H-3,1-benzothiazin-2-amine::MLS000696218::4H-3,1-benzothiazin-2-yl(2-pyridylmethyl)amine Oxysterols receptor LXR-beta Homo sapiens 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115027 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3838280 252664486 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238939 CN(C)c1ccc(nn1)C(C#N)c1ccccc1 InChI=1S/C14H14N4/c1-18(2)14-9-8-13(16-17-14)12(10-15)11-6-4-3-5-7-11/h3-9,12H,1-2H3 GWTNXVVXWAWFKQ-UHFFFAOYSA-N 115028 2-[6-(dimethylamino)pyridazin-3-yl]-2-phenyl-ethanenitrile::SMR000334028::cid_6409760::2-[6-(dimethylamino)-3-pyridazinyl]-2-phenylacetonitrile::2-[6-(dimethylamino)pyridazin-3-yl]-2-phenylacetonitrile::MLS000763691::2-[6-(dimethylamino)pyridazin-3-yl]-2-phenyl-acetonitrile Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6409760 252664487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238940 C\C(=N\OCc1ccc(Br)cc1)c1ccccn1 InChI=1S/C14H13BrN2O/c1-11(14-4-2-3-9-16-14)17-18-10-12-5-7-13(15)8-6-12/h2-9H,10H2,1H3 PBNSAAZNKRYIIS-UHFFFAOYSA-N 93843 (Z)-N-[(4-bromophenyl)methoxy]-1-(2-pyridinyl)ethanimine::(Z)-N-[(4-bromophenyl)methoxy]-1-pyridin-2-ylethanimine::cid_5903888::SMR000337380::1-(2-pyridinyl)-1-ethanone O-(4-bromobenzyl)oxime::MLS000755711::(Z)-N-[(4-bromophenyl)methoxy]-1-pyridin-2-yl-ethanimine::(Z)-(4-bromobenzyl)oxy-[1-(2-pyridyl)ethylidene]amine Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93843 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5903888 164035087 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238941 Clc1ccc(NN=C(C#N)C(=N)N2CCCCCC2)cc1 |w:6.5| InChI=1S/C15H18ClN5/c16-12-5-7-13(8-6-12)19-20-14(11-17)15(18)21-9-3-1-2-4-10-21/h5-8,18-19H,1-4,9-10H2 HIZSAVZDDKUQKB-UHFFFAOYSA-N 115029 SMR000306840::MLS000728147::(2E)-3-azepan-1-yl-2-[(4-chlorophenyl)hydrazono]-3-iminopropanenitrile::(2E)-3-(1-azepanyl)-2-[(4-chlorophenyl)hydrazinylidene]-3-iminopropanenitrile::cid_6401039::(2E)-3-azanylidene-3-(azepan-1-yl)-2-[(4-chlorophenyl)hydrazinylidene]propanenitrile::(1E)-2-(azepan-1-yl)-N-(4-chloroanilino)-2-iminoethanimidoyl cyanide::(2E)-3-(azepan-1-yl)-2-[(4-chlorophenyl)hydrazono]-3-imino-propionitrile Oxysterols receptor LXR-beta Homo sapiens 67493 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115029 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6401039 252664488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238942 Oc1ccccc1NC(=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 InChI=1S/C22H17N3O4S/c26-19-8-2-1-7-18(19)24-22(27)16-10-12-17(13-11-16)25-30(28,29)20-9-3-5-15-6-4-14-23-21(15)20/h1-14,25-26H,(H,24,27) VFPIDGYYGNFYMH-UHFFFAOYSA-N 49938 MLS000686747::N-(2-hydroxyphenyl)-4-(8-quinolinylsulfonylamino)benzamide::cid_5045370::SMR000339837::N-(2-hydroxyphenyl)-4-[(quinolin-8-ylsulfonyl)amino]benzamide::N-(2-hydroxyphenyl)-4-(quinolin-8-ylsulfonylamino)benzamide::N-(2-hydroxyphenyl)-4-(8-quinolylsulfonylamino)benzamide Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49938 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5045370 252630212 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238943 CCOC(=O)c1c(C)[nH]c(N=Nc2cccc(OC)c2)c1C |w:10.9| InChI=1S/C16H19N3O3/c1-5-22-16(20)14-10(2)15(17-11(14)3)19-18-12-7-6-8-13(9-12)21-4/h6-9,17H,5H2,1-4H3 PIPALFJORLHUMM-UHFFFAOYSA-N 76554 SMR000352587::ethyl (5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethylpyrrole-3-carboxylate::ethyl (5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethyl-pyrrole-3-carboxylate::(5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethyl-3-pyrrolecarboxylic acid ethyl ester::MLS001007421::cid_5340317::(5Z)-5-[(3-methoxyphenyl)hydrazono]-2,4-dimethyl-pyrrole-3-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76554 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76554&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5340317 252653732 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238944 Cc1cc(C(=O)CSc2cccc[n+]2[O-])c(C)n1-c1ccccc1 InChI=1S/C19H18N2O2S/c1-14-12-17(15(2)21(14)16-8-4-3-5-9-16)18(22)13-24-19-10-6-7-11-20(19)23/h3-12H,13H2,1-2H3 NZCDKYVOTDASIH-UHFFFAOYSA-N 115030 MLS000770655::1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-(1-oxidanidylpyridin-1-ium-2-yl)sulfanyl-ethanone::1-(2,5-dimethyl-1-phenylpyrrol-3-yl)-2-(1-oxidopyridin-1-ium-2-yl)sulfanylethanone::1-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-2-[(1-oxido-2-pyridin-1-iumyl)thio]ethanone::SMR000343845::cid_2453287::1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-[(1-oxidopyridin-1-ium-2-yl)thio]ethanone Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115030 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2453287 252664489 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238945 Cc1ccc(OCc2ccc(Br)cc2)c(n1)[N+]([O-])=O InChI=1S/C13H11BrN2O3/c1-9-2-7-12(13(15-9)16(17)18)19-8-10-3-5-11(14)6-4-10/h2-7H,8H2,1H3 IFDGERBZNBLBRL-UHFFFAOYSA-N 115031 SMR000343244::cid_3462706::MLS000517075::3-[(4-bromophenyl)methoxy]-6-methyl-2-nitropyridine::3-[(4-bromophenyl)methoxy]-6-methyl-2-nitro-pyridine::3-(4-bromobenzyl)oxy-6-methyl-2-nitro-pyridine Oxysterols receptor LXR-beta Homo sapiens 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3462706 252664490 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238946 CC(=NNC(=O)OC(C)(C)C)c1ccc[nH]1 |w:2.2| InChI=1S/C11H17N3O2/c1-8(9-6-5-7-12-9)13-14-10(15)16-11(2,3)4/h5-7,12H,1-4H3,(H,14,15) HDLSCKWETHIZPN-UHFFFAOYSA-N 115032 N-[[(1Z)-1-(2-pyrrolylidene)ethyl]amino]carbamic acid tert-butyl ester::cid_16196079::tert-butyl N-[[(1Z)-1-pyrrol-2-ylideneethyl]amino]carbamate::SMR000354192::MLS001017988::N-[[(1Z)-1-pyrrol-2-ylideneethyl]amino]carbamic acid tert-butyl ester Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115032 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16196079 252664491 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238947 [H]C12CC(C(=O)NCCN3C(=O)S\C(=C/c4ccc(OC)cc4)C3=O)C([H])(C1)C=C2 |c:31,THB:4:3:27:28.29| 49951 N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-3-thiazolidinyl]ethyl]-5-bicyclo[2.2.1]hept-2-enecarboxamide::MLS001010697::N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide::cid_5969645::N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide::SMR000352864::N-[2-[(5Z)-2,4-diketo-5-p-anisylidene-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49951 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49951&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5969645 252630225 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238948 CN=c1scc(-c2cccs2)n1N=C(C)c1ccco1 |w:12.13,1.0| InChI=1S/C14H13N3OS2/c1-10(12-5-3-7-18-12)16-17-11(9-20-14(17)15-2)13-6-4-8-19-13/h3-9H,1-2H3 SYZLBZVIQPEBQM-UHFFFAOYSA-N 115033 cid_9630484::(E)-3-[(E)-1-(furan-2-yl)ethylideneamino]-N-methyl-4-thiophen-2-yl-1,3-thiazol-2-imine::(E)-3-[(E)-1-(2-furanyl)ethylideneamino]-N-methyl-4-thiophen-2-yl-2-thiazolimine::MLS001033069::SMR000385489::(E)-1-(2-furyl)ethylidene-[2-methylimino-4-(2-thienyl)-4-thiazolin-3-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115033 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115033&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9630484 252664492 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238949 CCOc1cc(\C=C(/C#N)c2nc3ccccc3[nH]2)ccc1OC(C)C(O)=O InChI=1S/C21H19N3O4/c1-3-27-19-11-14(8-9-18(19)28-13(2)21(25)26)10-15(12-22)20-23-16-6-4-5-7-17(16)24-20/h4-11,13H,3H2,1-2H3,(H,23,24)(H,25,26) XAVGNURUZYXXSR-UHFFFAOYSA-N 53120 SMR000523914::2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyano-ethenyl]-2-ethoxy-phenoxy]propanoic acid::cid_5733133::2-{4-[2-(1H-Benzoimidazol-2-yl)-2-cyano-vinyl]-2-ethoxy-phenoxy}-propionic acid::2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-ethoxyphenoxy]propanoic acid::MLS001207004::2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyano-vinyl]-2-ethoxy-phenoxy]propionic acid Oxysterols receptor LXR-beta Homo sapiens 67487 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53120 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5733133 252633253 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238950 Cc1cc(C(=O)CSc2ncccn2)c(C)n1Cc1ccco1 InChI=1S/C17H17N3O2S/c1-12-9-15(13(2)20(12)10-14-5-3-8-22-14)16(21)11-23-17-18-6-4-7-19-17/h3-9H,10-11H2,1-2H3 LEXHQYYEOGWFKR-UHFFFAOYSA-N 115034 SMR000375854::cid_2083029::1-[1-(furan-2-ylmethyl)-2,5-dimethyl-pyrrol-3-yl]-2-pyrimidin-2-ylsulfanyl-ethanone::MLS000770557::1-[1-(furan-2-ylmethyl)-2,5-dimethylpyrrol-3-yl]-2-pyrimidin-2-ylsulfanylethanone::1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]-2-(2-pyrimidinylthio)ethanone::1-[1-(2-furfuryl)-2,5-dimethyl-pyrrol-3-yl]-2-(2-pyrimidylthio)ethanone Oxysterols receptor LXR-beta Homo sapiens 67511 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115034 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115034&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2083029 252664493 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238951 CSc1ccc(CN=Nc2ccc(Cl)c(c2)C(O)=O)cc1 |w:8.8| InChI=1S/C15H13ClN2O2S/c1-21-12-5-2-10(3-6-12)9-17-18-11-4-7-14(16)13(8-11)15(19)20/h2-8H,9H2,1H3,(H,19,20) WTSQAKFNXVWALA-UHFFFAOYSA-N 49991 cid_4122527::MLS000760472::2-chloro-5-[(N'E)-N'-[4-(methylthio)benzylidene]hydrazino]benzoic acid::2-chloranyl-5-[2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]benzoic acid::SMR000369743::2-chloro-5-[2-[[4-(methylthio)phenyl]methylidene]hydrazinyl]benzoic acid::2-chloro-5-[2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[(N''E)-N''-[4-(methylthio)benzylidene]hydrazino]benzoic acid::2-chloro-5-[N'-[4-(methylthio)benzylidene]hydrazino]benzoic acid Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49991 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896873 252630265 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238952 Cc1ccc(cc1Cl)-n1ncc2ccccc2c1=O InChI=1S/C15H11ClN2O/c1-10-6-7-12(8-14(10)16)18-15(19)13-5-3-2-4-11(13)9-17-18/h2-9H,1H3 NPRSYIMJIISRSC-UHFFFAOYSA-N 115036 MLS001032924::cid_2460931::2-(3-chloranyl-4-methyl-phenyl)phthalazin-1-one::2-(3-chloro-4-methylphenyl)phthalazin-1-one::2-(3-chloro-4-methylphenyl)-1-phthalazinone::SMR000363509::2-(3-chloro-4-methyl-phenyl)phthalazin-1-one Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115036 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115036&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2460931 252664494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238953 Cc1cccc(c1)N=Nc1cnc(N)s1 |w:7.7| InChI=1S/C10H10N4S/c1-7-3-2-4-8(5-7)13-14-9-6-12-10(11)15-9/h2-6H,1H3,(H2,11,12) ULNIXBAKBYRJCA-UHFFFAOYSA-N 76565 N-[(Z)-(2-imino-5-thiazolylidene)amino]-3-methylaniline::N-[(Z)-(2-azanylidene-1,3-thiazol-5-ylidene)amino]-3-methyl-aniline::cid_6418684::SMR000363211::N-[(Z)-(2-imino-1,3-thiazol-5-ylidene)amino]-3-methylaniline::MLS001018747::[(Z)-(2-imino-3-thiazolin-5-ylidene)amino]-(m-tolyl)amine Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76565 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76565&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6418684 252653743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238954 Cc1ccc2N=C(CC(=Nc2c1)c1ccccc1)C(Cl)Cl |c:5,8| InChI=1S/C17H14Cl2N2/c1-11-7-8-13-15(9-11)21-14(10-16(20-13)17(18)19)12-5-3-2-4-6-12/h2-9,17H,10H2,1H3 POCZRLSDYXJPKB-UHFFFAOYSA-N 115037 SMR000436379::cid_941833::2-[bis(chloranyl)methyl]-7-methyl-4-phenyl-3H-1,5-benzodiazepine::2-Dichloromethyl-7-methyl-4-phenyl-3H-benzo[b][1,4]diazepine::MLS000332968::2-(dichloromethyl)-7-methyl-4-phenyl-3H-1,5-benzodiazepine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115037 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115037&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 941833 252664495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238955 Nc1nc(N)c(C#N)c(Nc2ccc(Br)cc2)n1 InChI=1S/C11H9BrN6/c12-6-1-3-7(4-2-6)16-10-8(5-13)9(14)17-11(15)18-10/h1-4H,(H5,14,15,16,17,18) YTCJLQXQKYMGIW-UHFFFAOYSA-N 115038 2,4-diamino-6-(4-bromoanilino)-5-pyrimidinecarbonitrile::cid_251469::SMR000528326::MLS000736787::2,4-bis(azanyl)-6-[(4-bromophenyl)amino]pyrimidine-5-carbonitrile::2,4-diamino-6-(4-bromoanilino)pyrimidine-5-carbonitrile Oxysterols receptor LXR-beta Homo sapiens 67447 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115038 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115038&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 251469 252664496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238956 O=C1Nc2ccccc2C1C=Nc1ccccc1 |w:11.13| InChI=1S/C15H12N2O/c18-15-13(10-16-11-6-2-1-3-7-11)12-8-4-5-9-14(12)17-15/h1-10,13H,(H,17,18) QPEFRRMYOJKCMR-UHFFFAOYSA-N 115039 SMR000413803::cid_5474724::(3Z)-3-(anilinomethylidene)-1H-indol-2-one::MLS000777404::3-[1-Phenylamino-meth-(E)-ylidene]-1,3-dihydro-indol-2-one::(3Z)-3-(phenylazanylmethylidene)-1H-indol-2-one::(3Z)-3-(anilinomethylene)oxindole Oxysterols receptor LXR-beta Homo sapiens 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115039 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115039&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91554190 252664497 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238957 COc1cc(\C=C2\N3C=CC=CC3=C(C#N)C2=O)ccc1O |c:8,10,t:13| InChI=1S/C17H12N2O3/c1-22-16-9-11(5-6-15(16)20)8-14-17(21)12(10-18)13-4-2-3-7-19(13)14/h2-9,20H,1H3 QDKMHCPYYMHDEO-UHFFFAOYSA-N 115040 SMR000371201::(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-oxoindolizine-1-carbonitrile::(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-oxo-1-indolizinecarbonitrile::MLS000776195::(3E)-3-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-2-oxidanylidene-indolizine-1-carbonitrile::cid_6901173::(3E)-2-keto-3-vanillylidene-indolizine-1-carbonitrile Oxysterols receptor LXR-beta Homo sapiens 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115040 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115040&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6901173 252664498 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238958 CCOC(=O)c1csc(n1)-c1sccc1Br InChI=1S/C10H8BrNO2S2/c1-2-14-10(13)7-5-16-9(12-7)8-6(11)3-4-15-8/h3-5H,2H2,1H3 FHLHPRATYFGOOC-UHFFFAOYSA-N 115041 SMR000460989::2-(3-bromo-2-thiophenyl)-4-thiazolecarboxylic acid ethyl ester::ethyl 2-(3-bromo-2-thienyl)-1,3-thiazole-4-carboxylate::cid_2740372::MLS000860210::ethyl 2-(3-bromanylthiophen-2-yl)-1,3-thiazole-4-carboxylate::ethyl 2-(3-bromothiophen-2-yl)-1,3-thiazole-4-carboxylate::2-(3-bromo-2-thienyl)thiazole-4-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115041 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115041&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2740372 252664499 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238959 COc1ccc2[nH]c(cc2c1)C(=O)Nc1cccc(C)n1 InChI=1S/C16H15N3O2/c1-10-4-3-5-15(17-10)19-16(20)14-9-11-8-12(21-2)6-7-13(11)18-14/h3-9,18H,1-2H3,(H,17,19,20) OABFTKPNJBYGAF-UHFFFAOYSA-N 115042 5-methoxy-N-(6-methylpyridin-2-yl)-1H-indole-2-carboxamide::SMR000461198::cid_2742891::5-methoxy-N-(6-methyl-2-pyridinyl)-1H-indole-2-carboxamide::MLS000859321::5-methoxy-N-(6-methyl-2-pyridyl)-1H-indole-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67492 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115042 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115042&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2742891 252664500 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238960 CCOC(=O)c1cn[nH]c1NC(=S)Nc1ccccc1 InChI=1S/C13H14N4O2S/c1-2-19-12(18)10-8-14-17-11(10)16-13(20)15-9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H3,14,15,16,17,20) IROYJAHBNONSDB-UHFFFAOYSA-N 115043 cid_2816406::ethyl 5-[(anilinocarbothioyl)amino]-1H-pyrazole-4-carboxylate::SMR000459010::ethyl 5-(phenylcarbamothioylamino)-1H-pyrazole-4-carboxylate::MLS000858931::5-[[anilino(sulfanylidene)methyl]amino]-1H-pyrazole-4-carboxylic acid ethyl ester::5-(phenylthiocarbamoylamino)-1H-pyrazole-4-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115043 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115043&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2816406 252664501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238961 Brc1ccc(C=NNC(=O)c2cccs2)s1 InChI=1S/C10H7BrN2OS2/c11-9-4-3-7(16-9)6-12-13-10(14)8-2-1-5-15-8/h1-6H,(H,13,14) SCCFKSASSBYYBC-UHFFFAOYSA-N 77798 N-[(5-bromothiophen-2-yl)methylideneamino]thiophene-2-carboxamide::Thiophene-2-carboxylic acid [1-(5-bromo-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::N-[(5-bromo-2-thiophenyl)methylideneamino]-2-thiophenecarboxamide::SMR000434730::cid_574108::N-[(5-bromanylthiophen-2-yl)methylideneamino]thiophene-2-carboxamide::MLS000769902::N-[(5-bromo-2-thienyl)methyleneamino]thiophene-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67527 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77798 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77798&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 574108 252654704 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238962 Clc1ccc(Nc2ccc3ccccc3n2)cc1 InChI=1S/C15H11ClN2/c16-12-6-8-13(9-7-12)17-15-10-5-11-3-1-2-4-14(11)18-15/h1-10H,(H,17,18) ZHXBNPPHMUJAKW-UHFFFAOYSA-N 115044 N-(4-chlorophenyl)quinolin-2-amine::MLS001077258::SMR000473041::cid_3107275::N-(4-chlorophenyl)-2-quinolinamine::(4-chlorophenyl)-(2-quinolyl)amine Oxysterols receptor LXR-beta Homo sapiens 67486 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115044 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115044&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3107275 252664502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238963 Cc1nc(cs1)-c1ccc(NC(=O)c2ccc(Br)o2)cc1 InChI=1S/C15H11BrN2O2S/c1-9-17-12(8-21-9)10-2-4-11(5-3-10)18-15(19)13-6-7-14(16)20-13/h2-8H,1H3,(H,18,19) QKLDLURNVHPAKF-UHFFFAOYSA-N 115045 5-bromanyl-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]furan-2-carboxamide::5-bromo-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]-2-furamide::5-bromo-N-[4-(2-methyl-4-thiazolyl)phenyl]-2-furancarboxamide::SMR000477842::MLS001178354::cid_983644::5-bromo-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]furan-2-carboxamide::5-bromo-N-[4-(2-methylthiazol-4-yl)phenyl]-2-furamide Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115045 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115045&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 983644 252664503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238964 Cc1cc(ccc1O)N=Nc1ccc2ccccc2c1 |w:9.10| InChI=1S/C17H14N2O/c1-12-10-15(8-9-17(12)20)18-19-16-7-6-13-4-2-3-5-14(13)11-16/h2-11,20H,1H3 LVDFXHJGWPGUGU-UHFFFAOYSA-N 115046 MLS001180990::2-methyl-4-(2-naphthyldiazenyl)phenol::(4E)-2-methyl-4-(2-naphthalenylhydrazinylidene)-1-cyclohexa-2,5-dienone::SMR000477773::cid_23723128::(4E)-2-methyl-4-(naphthalen-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one::(4E)-2-methyl-4-(2-naphthylhydrazono)cyclohexa-2,5-dien-1-one Oxysterols receptor LXR-beta Homo sapiens 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115046 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115046&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23723128 252664504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238965 OCc1ccc(cc1)\N=N\c1ccccc1 InChI=1S/C13H12N2O/c16-10-11-6-8-13(9-7-11)15-14-12-4-2-1-3-5-12/h1-9,16H,10H2 KDTXPUDCLDUROO-UHFFFAOYSA-N 115047 SMR000475651::(4-phenyldiazenylphenyl)methanol::[4-(phenyldiazenyl)phenyl]methanol::MLS001180998::cid_555490::(4-phenylazophenyl)methanol Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115047 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 555490 252664505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238966 Oc1ccc(cc1)N=Nc1ccc2ccccc2c1 |w:8.9| InChI=1S/C16H12N2O/c19-16-9-7-14(8-10-16)17-18-15-6-5-12-3-1-2-4-13(12)11-15/h1-11,19H SDOPORHPKVAKOO-UHFFFAOYSA-N 115048 cid_7099036::4-(2-naphthyldiazenyl)phenol::MLS001180999::4-(naphthalen-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one::4-(2-naphthalenylhydrazinylidene)-1-cyclohexa-2,5-dienone::SMR000477767::4-(2-naphthylhydrazono)cyclohexa-2,5-dien-1-one Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115048 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115048&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7099036 252664506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238967 Cc1ccc(N=Nc2ccc(O)cc2)c(Br)c1 |w:5.4| InChI=1S/C13H11BrN2O/c1-9-2-7-13(12(14)8-9)16-15-10-3-5-11(17)6-4-10/h2-8,17H,1H3 YIDMWLUFNVJJHD-UHFFFAOYSA-N 115049 SMR000477771::4-[(2-bromo-4-methylphenyl)diazenyl]phenol::cid_5368817::4-[(2-bromo-4-methylphenyl)hydrazinylidene]-1-cyclohexa-2,5-dienone::4-[(2-bromanyl-4-methyl-phenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one::MLS001180977::4-[(2-bromo-4-methylphenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one::4-[(2-bromo-4-methyl-phenyl)hydrazono]cyclohexa-2,5-dien-1-one Oxysterols receptor LXR-beta Homo sapiens 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115049 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115049&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5368817 252664507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238968 Cc1ccc(SCCSc2ncccn2)cc1 InChI=1S/C13H14N2S2/c1-11-3-5-12(6-4-11)16-9-10-17-13-14-7-2-8-15-13/h2-8H,9-10H2,1H3 SRWOANFVXCQHMS-UHFFFAOYSA-N 115050 SMR000497824::2-({2-[(4-methylphenyl)thio]ethyl}thio)pyrimidine::2-[2-(4-methylphenyl)sulfanylethylsulfanyl]pyrimidine::cid_2948897::MLS001000858::2-[2-[(4-methylphenyl)thio]ethylthio]pyrimidine::2-[2-(p-tolylthio)ethylthio]pyrimidine Oxysterols receptor LXR-beta Homo sapiens 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115050 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115050&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2948897 252664508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238969 [O-][N+](=O)c1ccc2[nH+]c3[N-]c4ccccc4[N-]c3[nH+]c2c1 InChI=1S/C14H7N5O2/c20-19(21)8-5-6-11-12(7-8)18-14-13(17-11)15-9-3-1-2-4-10(9)16-14/h1-7H/q-2/p+2 SPKVHIXEGLYZIV-UHFFFAOYSA-P 115051 SMR000499522::MLS001163340::8-nitro-5,12-dihydroquinoxalino[2,3-b]quinoxaline::cid_3775159::3-nitro-5,12-dihydroquinoxalino[2,3-b]quinoxaline Oxysterols receptor LXR-beta Homo sapiens 67492 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115051 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115051&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3775159 252664509 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238970 [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)NC(=O)CCCc1ccccc1 |TLB:5:3:11:6.9.8,THB:2:1:9:3.12.5,2:3:9:1.11.8| 115052 SMR000497130::cid_2907426::N-1-adamantyl-4-phenylbutanamide::N-(1-adamantyl)-4-phenylbutanamide::MLS001000010::N-(1-adamantyl)-4-phenyl-butanamide::N-(1-adamantyl)-4-phenyl-butyramide Oxysterols receptor LXR-beta Homo sapiens 67516 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115052 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115052&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2907426 252664510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238971 c1ccc2cc(ccc2c1)-c1nc(no1)-c1cccnc1 InChI=1S/C17H11N3O/c1-2-5-13-10-14(8-7-12(13)4-1)17-19-16(20-21-17)15-6-3-9-18-11-15/h1-11H TVVPNYVYLPHGEZ-UHFFFAOYSA-N 115053 MLS000999694::3-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine::5-(2-naphthalenyl)-3-(3-pyridinyl)-1,2,4-oxadiazole::5-naphthalen-2-yl-3-pyridin-3-yl-1,2,4-oxadiazole::SMR000498906::cid_6462835::5-(2-naphthyl)-3-(3-pyridyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67519 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115053 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115053&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6462835 252664511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238972 Nc1ccc(cc1)C(=O)Nc1ccccc1N InChI=1S/C13H13N3O/c14-10-7-5-9(6-8-10)13(17)16-12-4-2-1-3-11(12)15/h1-8H,14-15H2,(H,16,17) QGMGHALXLXKCBD-UHFFFAOYSA-N 115054 N-(2-aminophenyl)-4-azanyl-benzamide::SMR000504768::MLS001209873::cid_42725::4-Amino-N-(2-amino-phenyl)-benzamide::4-amino-N-(2-aminophenyl)benzamide Oxysterols receptor LXR-beta Homo sapiens 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115054 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115054&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42725 252664512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238973 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 InChI=1S/C15H12FN3O3S2/c1-24(21,22)9-6-7-12-13(8-9)23-15(18-12)19-14(20)17-11-5-3-2-4-10(11)16/h2-8H,1H3,(H2,17,18,19,20) ILCYJNUFXUVUFX-UHFFFAOYSA-N 62134 1-(2-fluorophenyl)-3-(6-methylsulfonyl-1,3-benzothiazol-2-yl)urea::cid_2242090::MLS001163645::SMR000498638::N-(2-fluorophenyl)-N'-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]urea::1-(2-fluorophenyl)-3-(6-mesyl-1,3-benzothiazol-2-yl)urea Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=62134 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=62134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2242090 252641284 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238974 Cc1ccc(cc1C)-c1nc(no1)-c1ccncc1 InChI=1S/C15H13N3O/c1-10-3-4-13(9-11(10)2)15-17-14(18-19-15)12-5-7-16-8-6-12/h3-9H,1-2H3 OVRLQALANUTFEM-UHFFFAOYSA-N 115055 cid_888298::5-(3,4-dimethylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole::MLS001205218::4-[5-(3,4-Dimethyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::SMR000523591::5-(3,4-dimethylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115055 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115055&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 888298 252664513 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238975 Cc1cc2nn(nc2cc1N)-c1ccc(F)cc1 InChI=1S/C13H11FN4/c1-8-6-12-13(7-11(8)15)17-18(16-12)10-4-2-9(14)3-5-10/h2-7H,15H2,1H3 IGNZBKSODFTDHY-UHFFFAOYSA-N 115056 SMR000523818::MLS001210244::2-(4-Fluoro-phenyl)-6-methyl-2H-benzotriazol-5-ylamine::2-(4-fluorophenyl)-6-methyl-5-benzotriazolamine::2-(4-fluorophenyl)-6-methyl-benzotriazol-5-amine::2-(4-fluorophenyl)-6-methylbenzotriazol-5-amine::cid_822280::[2-(4-fluorophenyl)-6-methyl-benzotriazol-5-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67491 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115056 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115056&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 822280 252664514 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238976 Clc1ccccc1\C=C\C(=O)Nc1ccccc1 InChI=1S/C15H12ClNO/c16-14-9-5-4-6-12(14)10-11-15(18)17-13-7-2-1-3-8-13/h1-11H,(H,17,18) SPGGGKNPDWVLRC-UHFFFAOYSA-N 77817 SMR000459213::MLS000859034::N1-phenyl-3-(2-chlorophenyl)acrylamide::cid_737170::(E)-3-(2-chlorophenyl)-N-phenylprop-2-enamide::(E)-3-(2-chlorophenyl)-N-phenyl-2-propenamide::(E)-3-(2-chlorophenyl)-N-phenyl-prop-2-enamide::(E)-3-(2-chlorophenyl)-N-phenyl-acrylamide Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77817 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 737170 252654708 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238977 CCOc1ccc(cc1)-c1[n+]([O-])c2ccccc2n(O)c1=O InChI=1S/C16H14N2O4/c1-2-22-12-9-7-11(8-10-12)15-16(19)18(21)14-6-4-3-5-13(14)17(15)20/h3-10,21H,2H2,1H3 MNTAUQXUFRYRDE-UHFFFAOYSA-N 115057 3-(4-ethoxyphenyl)-4-oxidanidyl-1-oxidanyl-quinoxalin-4-ium-2-one::SMR000539699::cid_948254::3-(4-ethoxyphenyl)-1-hydroxy-4-oxidoquinoxalin-4-ium-2-one::3-(4-ethoxyphenyl)-1-hydroxy-4-oxido-2-quinoxalin-4-iumone::MLS001164235::1-hydroxy-4-oxido-3-p-phenetyl-quinoxalin-4-ium-2-one Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115057 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115057&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 948254 252664515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238978 Brc1ccc(o1)-c1noc(n1)-c1ccccn1 InChI=1S/C11H6BrN3O2/c12-9-5-4-8(16-9)10-14-11(17-15-10)7-3-1-2-6-13-7/h1-6H DBSUFYRXXVOXJQ-UHFFFAOYSA-N 115058 3-(5-bromo-2-furanyl)-5-(2-pyridinyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-pyridin-2-yl-1,2,4-oxadiazole::MLS001202032::cid_718328::3-(5-bromanylfuran-2-yl)-5-pyridin-2-yl-1,2,4-oxadiazole::SMR000565160::2-[3-(5-bromo-2-furyl)-1,2,4-oxadiazol-5-yl]pyridine::3-(5-bromo-2-furyl)-5-(2-pyridyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67498 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115058 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115058&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 718328 252664516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238979 COc1cccc(\C=C\c2ccc3cccc(O)c3n2)c1 InChI=1S/C18H15NO2/c1-21-16-6-2-4-13(12-16)8-10-15-11-9-14-5-3-7-17(20)18(14)19-15/h2-12,20H,1H3 SADQNNIVDUABSE-UHFFFAOYSA-N 50271181 cid_5731702::CHEMBL488140::2-(3-methoxystyryl)quinolin-8-ol Oxysterols receptor LXR-beta Homo sapiens 67470 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271181&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5731702 104116110 CHEMBL488140 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238980 CSc1ccccc1-c1nc(no1)-c1ccncc1 InChI=1S/C14H11N3OS/c1-19-12-5-3-2-4-11(12)14-16-13(17-18-14)10-6-8-15-9-7-10/h2-9H,1H3 KQNLSBFRXHXIFO-UHFFFAOYSA-N 76687 5-(2-methylsulfanylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole::MLS001165303::4-{5-[2-(methylsulfanyl)phenyl]-1,2,4-oxadiazol-3-yl}pyridine::cid_1486780::5-[2-(methylthio)phenyl]-3-pyridin-4-yl-1,2,4-oxadiazole::SMR000549795::5-[2-(methylthio)phenyl]-3-(4-pyridyl)-1,2,4-oxadiazole Oxysterols receptor LXR-beta Homo sapiens 67486 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76687 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76687&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1486780 252653864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238981 Clc1ccc(cc1)-c1cn2cc(Cl)ccc2n1 InChI=1S/C13H8Cl2N2/c14-10-3-1-9(2-4-10)12-8-17-7-11(15)5-6-13(17)16-12/h1-8H CFINUJBABHRHDT-UHFFFAOYSA-N 114931 MLS001166240::cid_717647::6-chloranyl-2-(4-chlorophenyl)imidazo[1,2-a]pyridine::SMR000549995::6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114931 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114931&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717647 252664393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238982 Nc1c(cnc2c(cnn12)-c1ccc(F)cc1)-c1cccs1 InChI=1S/C16H11FN4S/c17-11-5-3-10(4-6-11)12-9-20-21-15(18)13(8-19-16(12)21)14-2-1-7-22-14/h1-9H,18H2 ZPBHTNCLIWHQBB-UHFFFAOYSA-N 96015 3-(4-fluorophenyl)-6-thiophen-2-yl-pyrazolo[1,5-a]pyrimidin-7-amine::MLS001165963::3-(4-fluorophenyl)-6-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-amine::3-(4-fluorophenyl)-6-(2-thienyl)pyrazolo[1,5-a]pyrimidin-7-amine::3-(4-fluorophenyl)-6-thiophen-2-yl-7-pyrazolo[1,5-a]pyrimidinamine::SMR000550229::cid_1474449::[3-(4-fluorophenyl)-6-(2-thienyl)pyrazolo[1,5-a]pyrimidin-7-yl]amine Oxysterols receptor LXR-beta Homo sapiens 67517 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96015 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1474449 164037259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238983 Cc1ccc(cc1)-c1onc2ccc(cc12)C(O)=O InChI=1S/C15H11NO3/c1-9-2-4-10(5-3-9)14-12-8-11(15(17)18)6-7-13(12)16-19-14/h2-8H,1H3,(H,17,18) HLSBMOWPXCBDEU-UHFFFAOYSA-N 115059 cid_17015159::MLS001199620::SMR000560152::3-(4-methylphenyl)-2,1-benzoxazole-5-carboxylic acid::3-(4-methylphenyl)-2,1-benzisoxazole-5-carboxylic acid::3-(p-tolyl)anthranil-5-carboxylic acid Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115059 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17015159 252664517 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238984 COc1ccc(Nc2nccc(n2)-c2cccc(N)c2)cc1 InChI=1S/C17H16N4O/c1-22-15-7-5-14(6-8-15)20-17-19-10-9-16(21-17)12-3-2-4-13(18)11-12/h2-11H,18H2,1H3,(H,19,20,21) UYPUJNKDIZFXSD-UHFFFAOYSA-N 115060 SMR000560288::4-(3-aminophenyl)-N-(4-methoxyphenyl)-2-pyrimidinamine::cid_20855152::MLS001199466::4-(3-aminophenyl)-N-(4-methoxyphenyl)pyrimidin-2-amine::[4-(3-aminophenyl)pyrimidin-2-yl]-(4-methoxyphenyl)amine Oxysterols receptor LXR-beta Homo sapiens 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115060 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115060&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20855152 252664518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238985 Oc1cccc(\C=C\c2ccc3cccc(O)c3n2)c1 InChI=1S/C17H13NO2/c19-15-5-1-3-12(11-15)7-9-14-10-8-13-4-2-6-16(20)17(13)18-14/h1-11,19-20H ZGCNQHDVSASYMK-UHFFFAOYSA-N 114932 2-[(E)-2-(3-hydroxyphenyl)ethenyl]quinolin-8-ol::2-[(E)-2-(3-hydroxyphenyl)ethenyl]-8-quinolinol::MLS001196201::cid_5837141::SMR000558527::2-[(E)-2-(3-hydroxyphenyl)vinyl]quinolin-8-ol Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114932 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114932&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5837141 252664394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238986 Cc1cc2ncc(nc2cc1C)-c1ccccc1 InChI=1S/C16H14N2/c1-11-8-14-15(9-12(11)2)18-16(10-17-14)13-6-4-3-5-7-13/h3-10H,1-2H3 FQNCLVJEQCJWSU-UHFFFAOYSA-N 33408 cid_2048::CHEMBL7724::AG1295 Oxysterols receptor LXR-beta Homo sapiens 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33408 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33408&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2048 85267026 CHEMBL7724 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238987 Oc1ccccc1-c1cc([nH]n1)-c1ccc(Cl)cc1 InChI=1S/C15H11ClN2O/c16-11-7-5-10(6-8-11)13-9-14(18-17-13)12-3-1-2-4-15(12)19/h1-9,19H,(H,17,18) ZXVNJVRABSCRGU-UHFFFAOYSA-N 114933 (6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::cid_5333851::MLS001182178::(6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::SMR000567869::(6Z)-6-[5-(4-chlorophenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114933 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5333851 252664395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238988 N(c1nc(ns1)-c1ccccc1)c1ccccc1 InChI=1S/C14H11N3S/c1-3-7-11(8-4-1)13-16-14(18-17-13)15-12-9-5-2-6-10-12/h1-10H,(H,15,16,17) RMFQIIXCTLNZRC-UHFFFAOYSA-N 76702 MLS001193335::cid_8122161::SMR000590015::N,3-diphenyl-1,2,4-thiadiazol-5-amine::phenyl-(3-phenyl-1,2,4-thiadiazol-5-yl)amine Oxysterols receptor LXR-beta Homo sapiens 67574 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76702 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 8122161 252653879 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238989 Cc1csc(NC(=O)c2ccc3ccccc3n2)n1 InChI=1S/C14H11N3OS/c1-9-8-19-14(15-9)17-13(18)12-7-6-10-4-2-3-5-11(10)16-12/h2-8H,1H3,(H,15,17,18) ZXLDSLCUIHEUDZ-UHFFFAOYSA-N 76709 N-(4-methyl-1,3-thiazol-2-yl)quinoline-2-carboxamide::MLS001177468::cid_2105353::SMR000588905::N-(4-methyl-2-thiazolyl)-2-quinolinecarboxamide::N-(4-methylthiazol-2-yl)quinaldamide Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76709 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76709&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2105353 252653886 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238990 Cc1cc(NC(=O)CSc2nc3CCCc3cc2C#N)no1 InChI=1S/C15H14N4O2S/c1-9-5-13(19-21-9)18-14(20)8-22-15-11(7-16)6-10-3-2-4-12(10)17-15/h5-6H,2-4,8H2,1H3,(H,18,19,20) RZVWYJJYGVDSHM-UHFFFAOYSA-N 72976 2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)sulfanyl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide::2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-N-(5-methyl-3-isoxazolyl)acetamide::SMR000620232::MLS000948010::cid_4046943::2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)sulfanyl]-N-(5-methyl-1,2-oxazol-3-yl)ethanamide::2-[(3-cyano-1-pyrindan-2-yl)thio]-N-(5-methylisoxazol-3-yl)acetamide Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72976 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72976&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4046943 252650226 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238991 Cc1cnc(NC(=O)COc2ccc3CCCc3c2)s1 InChI=1S/C15H16N2O2S/c1-10-8-16-15(20-10)17-14(18)9-19-13-6-5-11-3-2-4-12(11)7-13/h5-8H,2-4,9H2,1H3,(H,16,17,18) KUBIMESJEMVBTH-UHFFFAOYSA-N 115061 MLS001071928::SMR000671611::2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-2-thiazolyl)acetamide::cid_2678142::2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-1,3-thiazol-2-yl)ethanamide::2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-1,3-thiazol-2-yl)acetamide::2-indan-5-yloxy-N-(5-methylthiazol-2-yl)acetamide Oxysterols receptor LXR-beta Homo sapiens 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115061 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2678142 252664519 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238992 CC(C)c1cc(CNC(=O)c2cc(COc3cc(C)c(Cl)c(C)c3)on2)on1 InChI=1S/C20H22ClN3O4/c1-11(2)17-7-15(27-23-17)9-22-20(25)18-8-16(28-24-18)10-26-14-5-12(3)19(21)13(4)6-14/h5-8,11H,9-10H2,1-4H3,(H,22,25) HSQNKCTXNXJGKS-UHFFFAOYSA-N 115062 5-[(4-chloranyl-3,5-dimethyl-phenoxy)methyl]-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-1,2-oxazole-3-carboxamide::MLS001100869::cid_24791023::5-[(4-chloro-3,5-dimethylphenoxy)methyl]-N-[(3-propan-2-yl-5-isoxazolyl)methyl]-3-isoxazolecarboxamide::5-[(4-chloro-3,5-dimethylphenoxy)methyl]-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-1,2-oxazole-3-carboxamide::SMR000670019::5-[(4-chloro-3,5-dimethyl-phenoxy)methyl]-N-[(3-isopropylisoxazol-5-yl)methyl]isoxazole-3-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115062 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24791023 252664520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238993 Fc1ccccc1-c1cc(on1)C(=O)NCC1CCCO1 InChI=1S/C15H15FN2O3/c16-12-6-2-1-5-11(12)13-8-14(21-18-13)15(19)17-9-10-4-3-7-20-10/h1-2,5-6,8,10H,3-4,7,9H2,(H,17,19) RVXJZUKMGCVBLR-UHFFFAOYSA-N 115063 cid_17096079::MLS001117105::SMR000627165::3-(2-fluorophenyl)-N-(2-oxolanylmethyl)-5-isoxazolecarboxamide::3-(2-fluorophenyl)-N-(oxolan-2-ylmethyl)-1,2-oxazole-5-carboxamide::3-(2-fluorophenyl)-N-(tetrahydrofurfuryl)isoxazole-5-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115063 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17096079 252664521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238994 CC1CCN(CCSc2ccc(C)cc2)C(=O)CC1 InChI=1S/C16H23NOS/c1-13-3-6-15(7-4-13)19-12-11-17-10-9-14(2)5-8-16(17)18/h3-4,6-7,14H,5,8-12H2,1-2H3 FKGRAOXAINTQBT-UHFFFAOYSA-N 115064 SMR000674011::cid_24793608::5-methyl-1-[2-(4-methylphenyl)sulfanylethyl]azepan-2-one::MLS000889883::5-methyl-1-[2-[(4-methylphenyl)thio]ethyl]-2-azepanone::5-methyl-1-[2-(p-tolylthio)ethyl]azepan-2-one Oxysterols receptor LXR-beta Homo sapiens 67487 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115064 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24793608 252664522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238995 Cc1ccnc(NC(=O)C2CCN(CC2)S(=O)(=O)c2c(C)c(C)cc(C)c2C)c1 InChI=1S/C22H29N3O3S/c1-14-6-9-23-20(12-14)24-22(26)19-7-10-25(11-8-19)29(27,28)21-17(4)15(2)13-16(3)18(21)5/h6,9,12-13,19H,7-8,10-11H2,1-5H3,(H,23,24,26) MZDTXKPSRGVGCR-UHFFFAOYSA-N 115065 SMR000711193::MLS001077534::cid_24816782::N-(4-methylpyridin-2-yl)-1-(2,3,5,6-tetramethylphenyl)sulfonylpiperidine-4-carboxamide::N-(4-methyl-2-pyridinyl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-4-piperidinecarboxamide::N-(4-methylpyridin-2-yl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-piperidine-4-carboxamide::N-(4-methyl-2-pyridyl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-isonipecotamide Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115065 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24816782 252664523 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238996 Cc1ccnc(NC(=O)CCNS(=O)(=O)c2ccc(C)c(C)c2)c1 InChI=1S/C17H21N3O3S/c1-12-6-8-18-16(10-12)20-17(21)7-9-19-24(22,23)15-5-4-13(2)14(3)11-15/h4-6,8,10-11,19H,7,9H2,1-3H3,(H,18,20,21) QSUUIHSTDKKWOA-UHFFFAOYSA-N 115066 cid_17505658::3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methylpyridin-2-yl)propanamide::MLS001078764::3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methyl-2-pyridinyl)propanamide::SMR000711202::3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methyl-2-pyridyl)propionamide Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115066 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17505658 252664524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238997 Brc1ccc(o1)C(=O)Nc1ccc2ccccc2c1 InChI=1S/C15H10BrNO2/c16-14-8-7-13(19-14)15(18)17-12-6-5-10-3-1-2-4-11(10)9-12/h1-9H,(H,17,18) NLAQCTYPUSFWMR-UHFFFAOYSA-N 115067 5-bromanyl-N-naphthalen-2-yl-furan-2-carboxamide::MLS001123663::5-bromo-N-naphthalen-2-ylfuran-2-carboxamide::SMR000658679::cid_765392::5-bromo-N-(2-naphthalenyl)-2-furancarboxamide::5-bromo-N-(2-naphthyl)-2-furamide Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115067 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115067&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 765392 252664525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238998 CCc1cc(sc1C)C(=O)Nc1ncccc1O InChI=1S/C13H14N2O2S/c1-3-9-7-11(18-8(9)2)13(17)15-12-10(16)5-4-6-14-12/h4-7,16H,3H2,1-2H3,(H,14,15,17) IKCSSRDSTDUSJA-UHFFFAOYSA-N 115068 SMR000688411::4-ethyl-N-(3-hydroxypyridin-2-yl)-5-methylthiophene-2-carboxamide::4-ethyl-N-(3-hydroxy-2-pyridinyl)-5-methyl-2-thiophenecarboxamide::4-ethyl-5-methyl-N-(3-oxidanylpyridin-2-yl)thiophene-2-carboxamide::MLS001141901::cid_24239799::4-ethyl-N-(3-hydroxy-2-pyridyl)-5-methyl-thiophene-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67512 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115068 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24239799 252664526 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238999 Fc1ccccc1COc1ccc(\C=C2/C(=O)N=C3SC(CC(=O)N4CCOCC4)=NN3C2=N)cc1 |c:31,t:18| InChI=1S/C25H22FN5O4S/c26-20-4-2-1-3-17(20)15-35-18-7-5-16(6-8-18)13-19-23(27)31-25(28-24(19)33)36-21(29-31)14-22(32)30-9-11-34-12-10-30/h1-8,13,27H,9-12,14-15H2 VIFLKBMBVPXIFY-UHFFFAOYSA-N 115069 cid_5824575::(6Z)-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-2-[2-(4-morpholinyl)-2-oxoethyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6Z)-5-azanylidene-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::MLS001147864::(6Z)-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-2-(2-morpholin-4-yl-2-oxoethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::SMR000647043::(6Z)-6-[4-(2-fluorobenzyl)oxybenzylidene]-5-imino-2-(2-keto-2-morpholino-ethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115069 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115069&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5824575 252664527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239000 CCc1sc(cc1C)C(=O)Nc1ncccc1O InChI=1S/C13H14N2O2S/c1-3-10-8(2)7-11(18-10)13(17)15-12-9(16)5-4-6-14-12/h4-7,16H,3H2,1-2H3,(H,14,15,17) BYZMKNREIRLNCQ-UHFFFAOYSA-N 115070 5-ethyl-4-methyl-N-(3-oxidanylpyridin-2-yl)thiophene-2-carboxamide::cid_24819635::SMR000688410::5-ethyl-N-(3-hydroxy-2-pyridinyl)-4-methyl-2-thiophenecarboxamide::MLS001157712::5-ethyl-N-(3-hydroxypyridin-2-yl)-4-methylthiophene-2-carboxamide::5-ethyl-N-(3-hydroxy-2-pyridyl)-4-methyl-thiophene-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115070 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24819635 252664528 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239001 Cc1cc2nc([nH]c2cc1C)-c1cccnc1SCC(=O)NCc1ccco1 InChI=1S/C21H20N4O2S/c1-13-9-17-18(10-14(13)2)25-20(24-17)16-6-3-7-22-21(16)28-12-19(26)23-11-15-5-4-8-27-15/h3-10H,11-12H2,1-2H3,(H,23,26)(H,24,25) BFJFBFZUMCMFKG-UHFFFAOYSA-N 115071 MLS001385447::cid_653562::2-[3-(5,6-dimethyl-1H-benzimidazol-2-yl)pyridin-2-yl]sulfanyl-N-(furan-2-ylmethyl)acetamide::SMR000007837::2-[3-(5,6-Dimethyl-1H-benzoimidazol-2-yl)-pyridin-2-ylsulfanyl]-N-furan-2-ylmethyl-acetamide::2-[3-(5,6-dimethyl-1H-benzimidazol-2-yl)pyridin-2-yl]sulfanyl-N-(furan-2-ylmethyl)ethanamide::2-[[3-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(2-furanylmethyl)acetamide::2-[[3-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridyl]thio]-N-(2-furfuryl)acetamide Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115071 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 653562 252664529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239002 C(=C/n1nnc2ccccc12)\c1ccccn1 InChI=1S/C13H10N4/c1-2-7-13-12(6-1)15-16-17(13)10-8-11-5-3-4-9-14-11/h1-10H UMOVCZMOBGPKME-UHFFFAOYSA-N 115072 1-[(E)-2-pyridin-2-ylethenyl]benzotriazole::SMR000841586::1-[(E)-2-(2-pyridinyl)ethenyl]benzotriazole::MLS001243444::cid_24892260::1-[(E)-2-(2-pyridyl)vinyl]benzotriazole Oxysterols receptor LXR-beta Homo sapiens 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115072 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24892260 252664530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239003 Oc1cccnc1NC(=O)c1ccc(cc1)C(=O)c1ccccc1 InChI=1S/C19H14N2O3/c22-16-7-4-12-20-18(16)21-19(24)15-10-8-14(9-11-15)17(23)13-5-2-1-3-6-13/h1-12,22H,(H,20,21,24) JWQRXWUNCADMIE-UHFFFAOYSA-N 115073 MLS001138688::cid_18109372::SMR000710070::N-(3-oxidanylpyridin-2-yl)-4-(phenylcarbonyl)benzamide::4-benzoyl-N-(3-hydroxypyridin-2-yl)benzamide::4-benzoyl-N-(3-hydroxy-2-pyridinyl)benzamide::4-benzoyl-N-(3-hydroxy-2-pyridyl)benzamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115073 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18109372 252664531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239004 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 InChI=1S/C14H12N2O3S/c1-8-10-7-9(18-2)3-4-11(10)19-12(8)13(17)16-14-15-5-6-20-14/h3-7H,1-2H3,(H,15,16,17) ASEAPAQCRCSWJA-UHFFFAOYSA-N 62519 MLS001161559::cid_2679217::5-methoxy-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::5-methoxy-3-methyl-N-(2-thiazolyl)-2-benzofurancarboxamide::SMR000715157::5-methoxy-3-methyl-N-thiazol-2-yl-coumarilamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=62519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=62519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2679217 252641647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239005 CCCCCc1nnc(NC(=O)C2=COCCO2)s1 |t:12| InChI=1S/C12H17N3O3S/c1-2-3-4-5-10-14-15-12(19-10)13-11(16)9-8-17-6-7-18-9/h8H,2-7H2,1H3,(H,13,15,16) HZAVOMKOIGBUNH-UHFFFAOYSA-N 115074 N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::SMR000713320::cid_18077761::MLS001128159::N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-1,4-dioxin-5-carboxamide::N-(5-amyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-p-dioxin-5-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115074 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18077761 252664532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239006 Oc1cccnc1NC(=O)c1cc2ccccc2o1 InChI=1S/C14H10N2O3/c17-10-5-3-7-15-13(10)16-14(18)12-8-9-4-1-2-6-11(9)19-12/h1-8,17H,(H,15,16,18) BAXKHKJVIHZIDW-UHFFFAOYSA-N 115075 cid_24982228::N-(3-oxidanylpyridin-2-yl)-1-benzofuran-2-carboxamide::N-(3-hydroxypyridin-2-yl)-1-benzofuran-2-carboxamide::N-(3-hydroxy-2-pyridinyl)-2-benzofurancarboxamide::MLS001138783::SMR000710078::N-(3-hydroxy-2-pyridyl)coumarilamide Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115075 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24982228 252664533 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239007 NC(NC(=O)c1nc(Cl)c(N)nc1N)=Nc1ccccc1 |w:14.15| InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21) NIOHELZQFBGCEO-UHFFFAOYSA-N 115076 cid_9604979::3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;methanesulfonic acid::SMR000326941::MLS002172443::3,5-bis(azanyl)-N-[azanyl(phenylazanyl)methylidene]-6-chloranyl-pyrazine-2-carboxamide;methanesulfonic acid::CHEMBL211502::Phenamil methanesulfonate salt::3,5-diamino-N-[amino(anilino)methylidene]-6-chloro-2-pyrazinecarboxamide;methanesulfonic acid::3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;mesylic acid Oxysterols receptor LXR-beta Homo sapiens 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115076 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4755 252664534 CHEMBL211502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239008 CC1CCC(CC1)NC(=O)c1cccn1C |(4.46,-5.42,;4.46,-3.88,;5.79,-3.11,;5.79,-1.57,;4.46,-.8,;3.12,-1.57,;3.12,-3.11,;4.46,.74,;5.79,1.51,;7.12,.74,;5.79,3.05,;7.04,3.96,;6.56,5.42,;5.02,5.42,;4.54,3.96,;3.08,3.48,)| InChI=1S/C13H20N2O/c1-10-5-7-11(8-6-10)14-13(16)12-4-3-9-15(12)2/h3-4,9-11H,5-8H2,1-2H3,(H,14,16) ATUVXHWHDWZCHS-UHFFFAOYSA-N 115077 SMR001269286::MLS002180256::1-methyl-N-(4-methylcyclohexyl)-2-pyrrolecarboxamide::cid_25161651::1-methyl-N-(4-methylcyclohexyl)pyrrole-2-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115077 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25161651 252664535 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239009 Clc1ccccc1Nc1nc2ccccc2o1 InChI=1S/C13H9ClN2O/c14-9-5-1-2-6-10(9)15-13-16-11-7-3-4-8-12(11)17-13/h1-8H,(H,15,16) YCVGAYXIQCGTFE-UHFFFAOYSA-N 115078 cid_714839::SMR001224462::MLS001359760::N-(2-chlorophenyl)-1,3-benzoxazol-2-amine::1,3-benzoxazol-2-yl-(2-chlorophenyl)amine Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115078 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 714839 252664536 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239010 CC1CCc2c(C1)sc(NC(=O)C1=COCCO1)c2C(N)=O |t:13| InChI=1S/C15H18N2O4S/c1-8-2-3-9-11(6-8)22-15(12(9)13(16)18)17-14(19)10-7-20-4-5-21-10/h7-8H,2-6H2,1H3,(H2,16,18)(H,17,19) GVZPXLRJSGCMBS-UHFFFAOYSA-N 115079 SMR001269060::N-(3-aminocarbonyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::cid_4390429::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxin-5-carboxamide::MLS002180030::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydrobenzothiophen-2-yl)-2,3-dihydro-p-dioxin-5-carboxamide Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115079 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4390429 252664537 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239011 C1[C@@H](N=C2Sc3ccccc3N12)c1ccccc1 |t:2| InChI=1S/C15H12N2S/c1-2-6-11(7-3-1)12-10-17-13-8-4-5-9-14(13)18-15(17)16-12/h1-9,12H,10H2 YGCWPCVAVSIFLO-UHFFFAOYSA-N 115080 cid_17747785::SMR001295168::MLS002206350::(2S)-2-phenyl-1,2-dihydroimidazo[2,1-b][1,3]benzothiazole Oxysterols receptor LXR-beta Homo sapiens 67135 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115080 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17747785 252664538 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239012 COc1ccc2cc(ncc2c1)-c1ccsc1 InChI=1S/C14H11NOS/c1-16-13-3-2-10-7-14(11-4-5-17-9-11)15-8-12(10)6-13/h2-9H,1H3 STOHIIPAPCWUAS-UHFFFAOYSA-N 115081 cid_44142278::7-methoxy-3-thiophen-3-yl-isoquinoline::MLS002402790::SMR001370559::7-methoxy-3-thiophen-3-ylisoquinoline::7-methoxy-3-(3-thiophenyl)isoquinoline::7-methoxy-3-(3-thienyl)isoquinoline Oxysterols receptor LXR-beta Homo sapiens 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115081 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44142278 252664539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239013 Cc1ccc(NC(=S)NC(=O)C2CCCC2)c(Br)c1 InChI=1S/C14H17BrN2OS/c1-9-6-7-12(11(15)8-9)16-14(19)17-13(18)10-4-2-3-5-10/h6-8,10H,2-5H2,1H3,(H2,16,17,18,19) MTKFDODZWQPBPV-UHFFFAOYSA-N 115082 N-[(2-bromo-4-methylphenyl)carbamothioyl]cyclopentanecarboxamide::N-[(2-bromo-4-methylanilino)-sulfanylidenemethyl]cyclopentanecarboxamide::MLS002249268::N-[(2-bromanyl-4-methyl-phenyl)carbamothioyl]cyclopentanecarboxamide::SMR001316709::cid_2375679::N-[(2-bromo-4-methyl-phenyl)thiocarbamoyl]cyclopentanecarboxamide Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115082 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2375679 252664540 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239014 Cc1cc(C(=O)COC(=O)c2cccnc2Cl)c(C)n1C InChI=1S/C15H15ClN2O3/c1-9-7-12(10(2)18(9)3)13(19)8-21-15(20)11-5-4-6-17-14(11)16/h4-7H,8H2,1-3H3 PDLUZBXYMBLRCL-UHFFFAOYSA-N 96074 cid_2097500::[2-oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloropyridine-3-carboxylate::2-chloro-3-pyridinecarboxylic acid [2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl] ester::[2-oxidanylidene-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloranylpyridine-3-carboxylate::SMR001314434::MLS002252084::2-chloronicotinic acid [2-keto-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] ester Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96074 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2097500 164037318 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239015 O=C(CSc1nnc(NCc2ccco2)s1)N1CCNC1=O InChI=1S/C12H13N5O3S2/c18-9(17-4-3-13-11(17)19)7-21-12-16-15-10(22-12)14-6-8-2-1-5-20-8/h1-2,5H,3-4,6-7H2,(H,13,19)(H,14,15) TZFNUHFQASBVGY-UHFFFAOYSA-N 115083 SMR001314205::1-[2-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanoyl]imidazolidin-2-one::MLS002251832::1-[2-[[5-(2-furanylmethylamino)-1,3,4-thiadiazol-2-yl]thio]-1-oxoethyl]-2-imidazolidinone::cid_8278086::1-[2-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]imidazolidin-2-one::1-[2-[[5-(2-furfurylamino)-1,3,4-thiadiazol-2-yl]thio]acetyl]-2-imidazolidinone Oxysterols receptor LXR-beta Homo sapiens 67538 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115083 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 8278086 252664541 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239016 Cn1cccc1C(=O)OCC(=O)Nc1sccc1C#N InChI=1S/C13H11N3O3S/c1-16-5-2-3-10(16)13(18)19-8-11(17)15-12-9(7-14)4-6-20-12/h2-6H,8H2,1H3,(H,15,17) OYXLNYBHYGONCV-UHFFFAOYSA-N 115084 [2-[(3-cyanothiophen-2-yl)amino]-2-oxoethyl] 1-methylpyrrole-2-carboxylate::cid_4003315::SMR000838755::1-methyl-2-pyrrolecarboxylic acid [2-[(3-cyano-2-thiophenyl)amino]-2-oxoethyl] ester::[2-[(3-cyanothiophen-2-yl)amino]-2-oxidanylidene-ethyl] 1-methylpyrrole-2-carboxylate::MLS002251955::1-methylpyrrole-2-carboxylic acid [2-[(3-cyano-2-thienyl)amino]-2-keto-ethyl] ester Oxysterols receptor LXR-beta Homo sapiens 67538 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115084 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115084&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4003315 252664542 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239017 CCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1ccco1 InChI=1S/C22H20N4O5/c1-3-10-26-18-14(21(28)25-11-6-5-9-17(25)23-18)13-15(22(29)30-4-2)19(26)24-20(27)16-8-7-12-31-16/h5-9,11-13H,3-4,10H2,1-2H3 SOPJQJLWSNJZCY-UHFFFAOYSA-N 49089 cid_1251509::MLS000052096::2-[2-furanyl(oxo)methyl]imino-5-oxo-1-propyl-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxylic acid ethyl ester::SMR000081413::ethyl 2-(furan-2-carbonylimino)-5-oxo-1-propyldipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate::ethyl 2-(2-furoylimino)-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate::ethyl 2-(furan-2-ylcarbonylimino)-5-oxidanylidene-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate::2-(2-furoylimino)-5-keto-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylic acid ethyl ester Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49089 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49089&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1251509 252629373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239018 Cc1ccc(NC(=S)N=C(NS(=O)(=O)c2ccccc2)c2ccccc2)cc1 |w:8.7| InChI=1S/C21H19N3O2S2/c1-16-12-14-18(15-13-16)22-21(27)23-20(17-8-4-2-5-9-17)24-28(25,26)19-10-6-3-7-11-19/h2-15H,1H3,(H2,22,23,24,27) AQPLGRYVAWVUSY-UHFFFAOYSA-N 55453 MLS000570272::1-[benzenesulfonylimino(phenyl)methyl]-3-(4-methylphenyl)thiourea::SMR000150345::1-[N-(benzenesulfonyl)-C-phenylcarbonimidoyl]-3-(4-methylphenyl)thiourea::1-[(E)-N-besyl-C-phenyl-carbonimidoyl]-3-(p-tolyl)thiourea::1-(4-methylphenyl)-3-[C-phenyl-N-(phenylsulfonyl)carbonimidoyl]thiourea::cid_2134365::1-(N-besyl-C-phenyl-carbonimidoyl)-3-(p-tolyl)thiourea Oxysterols receptor LXR-beta Homo sapiens 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55453 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55453&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5639749 252635450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239019 O=C(NNCc1ccccc1)c1ccccn1 InChI=1S/C13H13N3O/c17-13(12-8-4-5-9-14-12)16-15-10-11-6-2-1-3-7-11/h1-9,15H,10H2,(H,16,17) MAUBFEHMBSQXMM-UHFFFAOYSA-N 115086 N'-(phenylmethyl)pyridine-2-carbohydrazide::N'-(phenylmethyl)-2-pyridinecarbohydrazide::SMR001526814::MLS002608063::N'-benzylpyridine-2-carbohydrazide::cid_73101::N'-benzylpicolinohydrazide Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115086 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115086&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 73101 252664543 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239020 CCCCSc1ncnc2n(cnc12)C1CCCCO1 InChI=1S/C14H20N4OS/c1-2-3-8-20-14-12-13(15-9-16-14)18(10-17-12)11-6-4-5-7-19-11/h9-11H,2-8H2,1H3 WQBOXNLTSXJXII-UHFFFAOYSA-N 115087 MLS002608089::SMR001526840::6-(butylthio)-9-(2-oxanyl)purine::cid_236188::6-butylsulfanyl-9-(oxan-2-yl)purine::6-(butylthio)-9-tetrahydropyran-2-yl-purine Oxysterols receptor LXR-beta Homo sapiens 67448 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115087 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115087&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 236188 252664544 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239021 O=C(CC(=O)c1ccncc1)c1cccs1 InChI=1S/C12H9NO2S/c14-10(9-3-5-13-6-4-9)8-11(15)12-2-1-7-16-12/h1-7H,8H2 FFHNDRMNLBJSHI-UHFFFAOYSA-N 115088 1-pyridin-4-yl-3-thiophen-2-ylpropane-1,3-dione::cid_238435::1-pyridin-4-yl-3-thiophen-2-yl-propane-1,3-dione::SMR001527202::MLS002608454::1-(4-pyridyl)-3-(2-thienyl)propane-1,3-dione Oxysterols receptor LXR-beta Homo sapiens 67534 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115088 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115088&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 238435 252664545 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239022 CCN(CC)S(=O)(=O)c1cc(ccc1F)C(=O)OCC(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C27H26FN3O5S2/c1-4-31(5-2)38(34,35)24-15-19(9-12-21(24)28)27(33)36-16-25(32)29-20-10-7-18(8-11-20)26-30-22-13-6-17(3)14-23(22)37-26/h6-15H,4-5,16H2,1-3H3,(H,29,32) HHESFLBXVRUSCG-UHFFFAOYSA-N 49649 MLS000395004::cid_2338024::3-(diethylsulfamoyl)-4-fluorobenzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester::SMR000248406::[2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] 3-(diethylsulfamoyl)-4-fluorobenzoate::[2-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]amino]-2-oxidanylidene-ethyl] 3-(diethylsulfamoyl)-4-fluoranyl-benzoate::3-(diethylsulfamoyl)-4-fluoro-benzoic acid [2-keto-2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]ethyl] ester Oxysterols receptor LXR-beta Homo sapiens 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49649 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49649&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2338024 252629924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239023 O=NC(CCc1ccccc1)c1ccccc1 InChI=1S/C15H15NO/c17-16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10,15H,11-12H2 CDWDDQJXLPGASY-UHFFFAOYSA-N 115089 N-(1,3-diphenylpropylidene)hydroxylamine::MLS002638408::cid_225534::SMR001547891::1,3-diphenyl-1-propanone oxime::1,3-diphenylpropan-1-one oxime Oxysterols receptor LXR-beta Homo sapiens 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115089 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115089&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899744 252664546 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239024 Fc1ccccc1CSc1ncnc2n(cnc12)C1CCCCO1 InChI=1S/C17H17FN4OS/c18-13-6-2-1-5-12(13)9-24-17-15-16(19-10-20-17)22(11-21-15)14-7-3-4-8-23-14/h1-2,5-6,10-11,14H,3-4,7-9H2 ZARXBQKUTQSBNW-UHFFFAOYSA-N 115090 6-[(2-fluorophenyl)methylsulfanyl]-9-(oxan-2-yl)purine::MLS002667534::cid_243153::SMR001557300::6-[(2-fluorophenyl)methylthio]-9-(2-oxanyl)purine::6-[(2-fluorobenzyl)thio]-9-tetrahydropyran-2-yl-purine Oxysterols receptor LXR-beta Homo sapiens 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115090 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115090&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 243153 252664547 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239025 ClCCN(CCCl)P1(=O)Nc2ccccc2N1 InChI=1S/C10H14Cl2N3OP/c11-5-7-15(8-6-12)17(16)13-9-3-1-2-4-10(9)14-17/h1-4H,5-8H2,(H2,13,14,16) LECSXMDGCYIRGA-UHFFFAOYSA-N 115091 SMR001559444::MLS002693491::cid_248223::N,N-bis(2-chloroethyl)-2-oxidanylidene-1,3-dihydro-1,3,2-benzodiazaphosphol-2-amine::N,N-bis(2-chloroethyl)-2-oxo-1,3-dihydro-1,3,2-benzodiazaphosphol-2-amine::bis(2-chloroethyl)-(2-keto-1,3-dihydro-1,3,2-benzodiazaphosphol-2-yl)amine Oxysterols receptor LXR-beta Homo sapiens 67517 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115091 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115091&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 248223 252664548 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239026 C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Br)CO)O InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16) WOVKYSAHUYNSMH-UHFFFAOYSA-N 50016787 CHEMBL277625::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione(BrdUrd)::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (c-5-bromo-2-deoxyuridine)::cid_236184::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione(Bromodeoxyuridine) Oxysterols receptor LXR-beta Homo sapiens 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016787 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search U33 2GRB 236184 103928155 CHEMBL277625 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239027 C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)CO)O InChI=1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16) XQFRJNBWHJMXHO-UHFFFAOYSA-N 50016788 CHEMBL268690::cid_3687::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione (c-5-iodo-2-deoxyuridine)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione(IdUrd)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione(IDU)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione (IDU)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione( IDU) Oxysterols receptor LXR-beta Homo sapiens 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016788 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search ID2 1KI7 3687 103928156 CHEMBL268690 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239028 Nc1ncnc2n(C3OC(CO)C(O)C3O)c(Br)c(C#N)c12 InChI=1S/C12H12BrN5O4/c13-9-4(1-14)6-10(15)16-3-17-11(6)18(9)12-8(21)7(20)5(2-19)22-12/h3,5,7-8,12,19-21H,2H2,(H2,15,16,17) VGLVPHRWFSFJJL-UHFFFAOYSA-N 97027 4-azanyl-6-bromanyl-7-[5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile::SMR001566812::4-amino-6-bromo-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile::6-Bromotoyocamycin::cid_270861::MLS002703003::4-amino-6-bromo-7-[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-pyrrolo[2,3-d]pyrimidinecarbonitrile::4-amino-6-bromo-7-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonitrile Oxysterols receptor LXR-beta Homo sapiens 67481 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97027 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 270861 164038271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239029 Nc1ccc-2c(Cc3cc(N)c(Cl)cc-23)c1 InChI=1S/C13H11ClN2/c14-12-6-11-8(5-13(12)16)3-7-4-9(15)1-2-10(7)11/h1-2,4-6H,3,15-16H2 HNVPFPLBIJCROA-UHFFFAOYSA-N 115092 3-chloranyl-9H-fluorene-2,7-diamine::3-chloro-9H-fluorene-2,7-diamine::SMR001570152::MLS002703433::cid_263564::(7-amino-3-chloro-9H-fluoren-2-yl)amine Oxysterols receptor LXR-beta Homo sapiens 67414 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115092 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115092&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 263564 252664549 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239030 CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24) CBPJQFCAFFNICX-UHFFFAOYSA-N 115093 (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid::(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid::cid_1549133::SMR001562137::MLS002695993::(2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-methylpentanoic acid::Fmoc-L-leucine::(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-valeric acid Oxysterols receptor LXR-beta Homo sapiens 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115093 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115093&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1549133 252664550 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239031 O=c1n(CCc2ccccc2)nnc2ccccc12 InChI=1S/C15H13N3O/c19-15-13-8-4-5-9-14(13)16-17-18(15)11-10-12-6-2-1-3-7-12/h1-9H,10-11H2 LNSOYWFCGVLLTC-UHFFFAOYSA-N 115094 SMR001797456::cid_277303::MLS002919856::3-(2-phenylethyl)-1,2,3-benzotriazin-4-one::3-phenethyl-1,2,3-benzotriazin-4-one Oxysterols receptor LXR-beta Homo sapiens 67431 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115094 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 277303 252664551 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239032 C1CN=C(O1)c1ccc(cc1)\N=N\c1ccccc1 |c:2| InChI=1S/C15H13N3O/c1-2-4-13(5-3-1)17-18-14-8-6-12(7-9-14)15-16-10-11-19-15/h1-9H,10-11H2 KNELIOTUPCHJCS-UHFFFAOYSA-N 115095 [4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]-phenyldiazene::MLS003106519::cid_293475::[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]-phenyl-diazene::[4-(4,5-dihydrooxazol-2-yl)phenyl]-phenyldiazene::SMR001821418::[4-(2-oxazolin-2-yl)phenyl]-phenyl-diazene Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115095 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 293475 252664552 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239033 CN(C)c1ccc(cc1)\N=N\c1nccs1 InChI=1S/C11H12N4S/c1-15(2)10-5-3-9(4-6-10)13-14-11-12-7-8-16-11/h3-8H,1-2H3 GYNBRTUYPVOSGE-UHFFFAOYSA-N 115096 SMR001821629::N,N-dimethyl-4-(1,3-thiazol-2-yldiazenyl)aniline::Benzenamine, N,N-dimethyl-4-(2-thiazolylazo)-::cid_298444::N,N-dimethyl-4-(2-thiazolylazo)aniline::MLS003106739::dimethyl-(4-thiazol-2-ylazophenyl)amine Oxysterols receptor LXR-beta Homo sapiens 67406 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115096 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 298444 252664553 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239034 Nc1c(OS(=O)(=O)c2ccccc2)cccc1OS(=O)(=O)c1ccccc1 InChI=1S/C18H15NO6S2/c19-18-16(24-26(20,21)14-8-3-1-4-9-14)12-7-13-17(18)25-27(22,23)15-10-5-2-6-11-15/h1-13H,19H2 LQTOXLMJIIGBGG-UHFFFAOYSA-N 115097 cid_328728::benzenesulfonic acid [2-amino-3-(benzenesulfonyloxy)phenyl] ester::SMR001831427::[2-amino-3-(benzenesulfonyloxy)phenyl] benzenesulfonate::[2-azanyl-3-(phenylsulfonyloxy)phenyl] benzenesulfonate::MLS003115861::benzenesulfonic acid (2-amino-3-besyloxy-phenyl) ester Oxysterols receptor LXR-beta Homo sapiens 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115097 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 328728 252664554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239035 CCSCC(C)(C)n1[nH]c2ccccc2c1=O InChI=1S/C13H18N2OS/c1-4-17-9-13(2,3)15-12(16)10-7-5-6-8-11(10)14-15/h5-8,14H,4,9H2,1-3H3 OHRKOWRVNYKISA-UHFFFAOYSA-N 115098 2-[1-(ethylthio)-2-methylpropan-2-yl]-1H-indazol-3-one::SMR001856244::cid_46904954::MLS003151649::2-(1-ethylsulfanyl-2-methyl-propan-2-yl)-1H-indazol-3-one::2-(1-ethylsulfanyl-2-methylpropan-2-yl)-1H-indazol-3-one::2-[2-(ethylthio)-1,1-dimethyl-ethyl]indazolin-3-one Oxysterols receptor LXR-beta Homo sapiens 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115098 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115098&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46904954 252664555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239036 CN(C)CCNc1ncnc2n(cnc12)[C@H]1CN(Cc2cccnc2)C[C@@H](CO)O1 InChI=1S/C20H28N8O2/c1-26(2)7-6-22-19-18-20(24-13-23-19)28(14-25-18)17-11-27(10-16(12-29)30-17)9-15-4-3-5-21-8-15/h3-5,8,13-14,16-17,29H,6-7,9-12H2,1-2H3,(H,22,23,24) SHRZCAMKJQZFMI-UHFFFAOYSA-N 115099 MLS003120854::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]purin-9-yl]-4-(pyridin-3-ylmethyl)morpholin-2-yl]methanol::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]-9-purinyl]-4-(3-pyridinylmethyl)-2-morpholinyl]methanol::SMR001273231::cid_46943664::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]purin-9-yl]-4-(3-pyridylmethyl)morpholin-2-yl]methanol Oxysterols receptor LXR-beta Homo sapiens 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115099 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46943664 252664556 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239037 OC(c1nc(cs1)-c1cnc2ccccc2c1)c1ccccc1 InChI=1S/C19H14N2OS/c22-18(13-6-2-1-3-7-13)19-21-17(12-23-19)15-10-14-8-4-5-9-16(14)20-11-15/h1-12,18,22H MXQGDJZHLDDIMS-UHFFFAOYSA-N 115100 SMR001277142::phenyl-(4-quinolin-3-yl-1,3-thiazol-2-yl)methanol::phenyl-[4-(3-quinolinyl)-2-thiazolyl]methanol::cid_46948381::MLS003122278::phenyl-[4-(3-quinolyl)thiazol-2-yl]methanol Oxysterols receptor LXR-beta Homo sapiens 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115100 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115100&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46948381 252664557 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239038 Cc1cc(-c2ccncc2)n2ncc(-c3ccccc3)c2n1 InChI=1S/C18H14N4/c1-13-11-17(15-7-9-19-10-8-15)22-18(21-13)16(12-20-22)14-5-3-2-4-6-14/h2-12H,1H3 BDYLEIKJEYPCEO-UHFFFAOYSA-N 68333 5-methyl-3-phenyl-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine::SR-03000000952-1::5-methyl-3-phenyl-7-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine;2,2,2-tris(fluoranyl)ethanoic acid::5-methyl-3-phenyl-7-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;2,2,2-trifluoroacetic acid::cid_42640810::5-methyl-3-phenyl-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine;2,2,2-trifluoroacetic acid Oxysterols receptor LXR-beta Homo sapiens 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68333 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42640811 252646517 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239039 OCCN1CCN(CC1)c1cnc(cn1)-c1ccsc1 InChI=1S/C14H18N4OS/c19-7-6-17-2-4-18(5-3-17)14-10-15-13(9-16-14)12-1-8-20-11-12/h1,8-11,19H,2-7H2 NVOROOKFXAUPKA-UHFFFAOYSA-N 115102 cid_49778774::2-[4-[5-(3-thiophenyl)-2-pyrazinyl]-1-piperazinyl]ethanol::MLS003123237::SMR001454231::2-[4-(5-thiophen-3-ylpyrazin-2-yl)piperazin-1-yl]ethanol::2-[4-[5-(3-thienyl)pyrazin-2-yl]piperazino]ethanol Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115102 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49778774 252664558 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239040 CC(C)C(N)c1csc(Nc2nncc3ccccc23)n1 InChI=1S/C15H17N5S/c1-9(2)13(16)12-8-21-15(18-12)19-14-11-6-4-3-5-10(11)7-17-20-14/h3-9,13H,16H2,1-2H3,(H,18,19,20) GGSBPRXPSOAPKM-UHFFFAOYSA-N 115103 4-(1-amino-2-methylpropyl)-N-(1-phthalazinyl)-2-thiazolamine::cid_49789405::MLS003123755::SMR001291797::4-(1-azanyl-2-methyl-propyl)-N-phthalazin-1-yl-1,3-thiazol-2-amine::4-(1-amino-2-methylpropyl)-N-phthalazin-1-yl-1,3-thiazol-2-amine::[4-(1-amino-2-methyl-propyl)thiazol-2-yl]-phthalazin-1-yl-amine Oxysterols receptor LXR-beta Homo sapiens 67135 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115103 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49789405 252664559 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239041 CN(C)c1cccc(c1)-c1cc(Nc2ccc(O)cc2C)ncn1 InChI=1S/C19H20N4O/c1-13-9-16(24)7-8-17(13)22-19-11-18(20-12-21-19)14-5-4-6-15(10-14)23(2)3/h4-12,24H,1-3H3,(H,20,21,22) WMJMKQUQNODCMX-UHFFFAOYSA-N 115104 cid_49790647::4-[[6-[3-(dimethylamino)phenyl]pyrimidin-4-yl]amino]-3-methylphenol::4-[[6-[3-(dimethylamino)phenyl]-4-pyrimidinyl]amino]-3-methylphenol::MLS003123197::SMR001454153::4-[[6-[3-(dimethylamino)phenyl]pyrimidin-4-yl]amino]-3-methyl-phenol Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115104 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115104&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49790647 252664560 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239042 Cc1c(oc2ccccc12)C(=O)Nc1nccs1 InChI=1S/C13H10N2O2S/c1-8-9-4-2-3-5-10(9)17-11(8)12(16)15-13-14-6-7-18-13/h2-7H,1H3,(H,14,15,16) RDJWFCYOWJFLNV-UHFFFAOYSA-N 114954 3-methyl-N-(2-thiazolyl)-2-benzofurancarboxamide::SMR000715153::cid_4750125::MLS001077610::3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::3-methyl-N-thiazol-2-yl-coumarilamide Oxysterols receptor LXR-beta Homo sapiens 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114954 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4750125 252664416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239043 CC(=Nc1ccc(Cl)cc1N)c1c(O)cc(C)oc1=O |w:2.2| InChI=1S/C14H13ClN2O3/c1-7-5-12(18)13(14(19)20-7)8(2)17-11-4-3-9(15)6-10(11)16/h3-6,18H,16H2,1-2H3 IXSQQLXHDWOVBS-UHFFFAOYSA-N 115105 (3Z)-3-[1-[(2-azanyl-4-chloranyl-phenyl)amino]ethylidene]-6-methyl-pyran-2,4-dione::SMR001875158::(3Z)-3-[1-(2-amino-4-chloroanilino)ethylidene]-6-methylpyran-2,4-dione::MLS003171254::cid_5948348::(3Z)-3-[1-(2-amino-4-chloro-anilino)ethylidene]-6-methyl-pyran-2,4-quinone Oxysterols receptor LXR-beta Homo sapiens 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115105 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115105&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5948348 252664561 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239044 COc1ccc2oc3cc(NCCN(C)C)ccc3c(=O)c2c1 InChI=1S/C18H20N2O3/c1-20(2)9-8-19-12-4-6-14-17(10-12)23-16-7-5-13(22-3)11-15(16)18(14)21/h4-7,10-11,19H,8-9H2,1-3H3 XPEPALZZESYTMY-UHFFFAOYSA-N 115106 SMR001875249::MLS003171348::6-[2-(dimethylamino)ethylamino]-2-methoxy-9-xanthenone::cid_341914::6-[2-(dimethylamino)ethylamino]-2-methoxy-xanthen-9-one::6-[2-(dimethylamino)ethylamino]-2-methoxyxanthen-9-one::6-[2-(dimethylamino)ethylamino]-2-methoxy-xanthone Oxysterols receptor LXR-beta Homo sapiens 67460 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115106 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115106&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 341914 252664562 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239045 CN(C)c1ccc2c(n1)oc1ccccc1c2=O InChI=1S/C14H12N2O2/c1-16(2)12-8-7-10-13(17)9-5-3-4-6-11(9)18-14(10)15-12/h3-8H,1-2H3 KXXTUVAJDQJMJK-UHFFFAOYSA-N 115107 MLS003373966::2-(dimethylamino)-5-[1]benzopyrano[2,3-b]pyridinone::SMR002048754::5H- 1 Benzopyrano 2,3-b pyridin-5-one, 2-(Dimethylamino)-::cid_360210::2-(dimethylamino)chromeno[2,3-b]pyridin-5-one Oxysterols receptor LXR-beta Homo sapiens 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115107 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115107&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 360210 252664563 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239046 Cc1cc(C)n2c(NC3CCCC3)c(nc2n1)-c1cc2ccccc2o1 InChI=1S/C21H22N4O/c1-13-11-14(2)25-20(23-16-8-4-5-9-16)19(24-21(25)22-13)18-12-15-7-3-6-10-17(15)26-18/h3,6-7,10-12,16,23H,4-5,8-9H2,1-2H3 KOTKEOPVHGKCMR-UHFFFAOYSA-N 115108 SMR002249893::cid_53301193::MLS003589658::2-(benzofuran-2-yl)-N-cyclopentyl-5,7-dimethylimidazo[1,2-a]pyrimidin-3-amine::2-(1-benzofuran-2-yl)-N-cyclopentyl-5,7-dimethylimidazo[1,2-a]pyrimidin-3-amine::2-(2-benzofuranyl)-N-cyclopentyl-5,7-dimethyl-3-imidazo[1,2-a]pyrimidinamine::2-(1-benzofuran-2-yl)-N-cyclopentyl-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-amine::[2-(benzofuran-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-yl]-cyclopentyl-amine Oxysterols receptor LXR-beta Homo sapiens 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115108 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115108&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53301193 252664564 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239047 CN(C)c1cccc(c1)-c1cnc(s1)N1CCC(CC1)C(N)=O InChI=1S/C17H22N4OS/c1-20(2)14-5-3-4-13(10-14)15-11-19-17(23-15)21-8-6-12(7-9-21)16(18)22/h3-5,10-12H,6-9H2,1-2H3,(H2,18,22) QSIYOOLBRHGSSD-UHFFFAOYSA-N 115109 1-[5-[3-(dimethylamino)phenyl]-2-thiazolyl]-4-piperidinecarboxamide;2,2,2-trifluoroacetic acid::1-[5-[3-(dimethylamino)phenyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::SMR001522596::MLS002607722::cid_53338831::1-[5-[3-(dimethylamino)phenyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;2,2,2-trifluoroacetic acid::1-[5-[3-(dimethylamino)phenyl]thiazol-2-yl]isonipecotamide;2,2,2-trifluoroacetic acid Oxysterols receptor LXR-beta Homo sapiens 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115109 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115109&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46907664 252664565 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239048 O=C(NC1CCC1)c1ccc(cn1)C#CC1CC1 InChI=1S/C15H16N2O/c18-15(17-13-2-1-3-13)14-9-8-12(10-16-14)7-6-11-4-5-11/h8-11,13H,1-5H2,(H,17,18) GAGAPXLUCSJVRL-UHFFFAOYSA-N 115110 N-cyclobutyl-5-(2-cyclopropylethynyl)-2-pyridinecarboxamide;hydrochloride::MLS003874881::cid_53384838::N-cyclobutyl-5-(2-cyclopropylethynyl)pyridine-2-carboxamide;hydrochloride::SMR002531665::N-cyclobutyl-5-(2-cyclopropylethynyl)picolinamide;hydrochloride Oxysterols receptor LXR-beta Homo sapiens 67540 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115110 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53384869 252664566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239049 CCCCCCCCN1C(=O)[C@@H](CC(=O)NCC#C)C[C@@]2([C@H](O[C@H](C=C12)C(C)C)C1CC1)C(=O)OC |t:24| InChI=1S/C29H44N2O5/c1-6-8-9-10-11-12-16-31-24-18-23(20(3)4)36-26(21-13-14-21)29(24,28(34)35-5)19-22(27(31)33)17-25(32)30-15-7-2/h2,18,20-23,26H,6,8-17,19H2,1,3-5H3,(H,30,32) ZYJFYPRYFBOXTI-UHFFFAOYSA-N 115111 (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003874257::cid_60156978::SMR002530922::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxidanylidene-3-[2-oxidanylidene-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::(3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(propargylamino)ethyl]-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester Oxysterols receptor LXR-beta Homo sapiens 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115111 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 60156978 252664567 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239050 COC(=O)[C@@]12CCCCC=C1N(CC=C)C(=O)[C@H]2CC(=O)N1CCSCC1 |c:9| InChI=1S/C20H28N2O4S/c1-3-9-22-16-7-5-4-6-8-20(16,19(25)26-2)15(18(22)24)14-17(23)21-10-12-27-13-11-21/h3,7,15H,1,4-6,8-14H2,2H3 YNXKXWXNLSKNND-UHFFFAOYSA-N 115112 SMR003089419::MLS004259454::methyl (3S,3aR)-2-oxo-3-(2-oxo-2-thiomorpholin-4-ylethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylate::cid_60158113::(3S,3aR)-2-oxo-3-(2-oxo-2-thiomorpholin-4-ylethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylic acid methyl ester::methyl (3S,3aR)-2-oxidanylidene-3-(2-oxidanylidene-2-thiomorpholin-4-yl-ethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylate::(3S,3aR)-1-allyl-2-keto-3-(2-keto-2-thiomorpholino-ethyl)-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylic acid methyl ester Oxysterols receptor LXR-beta Homo sapiens 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC 11/13/2013 8/8/2014 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115112 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115112&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 60158113 252664568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1