BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 259075 S(c1ccccn1)c1ncnc2c3ccccc3oc12 InChI=1S/C15H9N3OS/c1-2-6-11-10(5-1)13-14(19-11)15(18-9-17-13)20-12-7-3-4-8-16-12/h1-9H DPEHOXYNMRXRAB-UHFFFAOYSA-N 128202 SMR000010569::MLS000071568::4-pyridin-2-ylsulfanyl-[1]benzofuro[3,2-d]pyrimidine::4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine::4-(Pyridin-2-ylsulfanyl)-benzo[4,5]furo[3,2-d]pyrimidine::cid_624350::4-(2-pyridylthio)benzofuro[3,2-d]pyrimidine Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128202 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128202&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 624350 225154546 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259076 Cc1ccc(Nc2c3CCCc3nc3ncnn23)cc1 InChI=1S/C15H15N5/c1-10-5-7-11(8-6-10)18-14-12-3-2-4-13(12)19-15-16-9-17-20(14)15/h5-9,18H,2-4H2,1H3 NDQSNPBQXRUCFE-UHFFFAOYSA-N 128203 (6,7-Dihydro-5H-cyclopenta[d][1,2,4]triazolo[1,5-a]pyrimidin-8-yl)-p-tolyl-amine::MLS000033766::SMR000007674::cid_653280 Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128203 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128203&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 653280 252664613 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259077 Cn1ncc(Cl)c1C(=O)N1CCc2ccccc12 InChI=1S/C13H12ClN3O/c1-16-12(10(14)8-15-16)13(18)17-7-6-9-4-2-3-5-11(9)17/h2-5,8H,6-7H2,1H3 UZRXHOCXKVNHOM-UHFFFAOYSA-N 128204 (4-chloro-2-methyl-3-pyrazolyl)-(2,3-dihydroindol-1-yl)methanone::SMR000036473::cid_660340::(4-chloro-2-methylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::(4-chloranyl-2-methyl-pyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::MLS000036247::(4-chloro-2-methyl-pyrazol-3-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128204 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128204&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 660340 225154547 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259078 C1Oc2ccc(cc2O1)C1=Nn2c(SC1)nnc2C1CCCCC1 |t:11| InChI=1S/C17H18N4O2S/c1-2-4-11(5-3-1)16-18-19-17-21(16)20-13(9-24-17)12-6-7-14-15(8-12)23-10-22-14/h6-8,11H,1-5,9-10H2 VWFLYBOWHWEJAM-UHFFFAOYSA-N 128205 MLS000081443::cid_662624::SMR000043293::6-(1,3-benzodioxol-5-yl)-3-cyclohexyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128205 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128205&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 662624 225154548 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259079 Cc1cc(C(=O)N2CCc3ccccc23)n(n1)-c1ccccc1 InChI=1S/C19H17N3O/c1-14-13-18(22(20-14)16-8-3-2-4-9-16)19(23)21-12-11-15-7-5-6-10-17(15)21/h2-10,13H,11-12H2,1H3 RBCXSMRMGKSERS-UHFFFAOYSA-N 128206 SMR000094747::MLS000117799::2,3-dihydroindol-1-yl-(5-methyl-2-phenylpyrazol-3-yl)methanone::2,3-dihydroindol-1-yl-(5-methyl-2-phenyl-3-pyrazolyl)methanone::cid_5308164::2,3-dihydroindol-1-yl-(5-methyl-2-phenyl-pyrazol-3-yl)methanone::indolin-1-yl-(5-methyl-2-phenyl-pyrazol-3-yl)methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128206 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128206&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5308164 225154549 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259080 COc1cccc(c1)-c1csc(NC(=O)C2CC2)n1 InChI=1S/C14H14N2O2S/c1-18-11-4-2-3-10(7-11)12-8-19-14(15-12)16-13(17)9-5-6-9/h2-4,7-9H,5-6H2,1H3,(H,15,16,17) JGLVRKAKSRQNOU-UHFFFAOYSA-N 44773 cid_4673629::N-[4-(3-methoxyphenyl)-2-thiazolyl]cyclopropanecarboxamide::MLS000103167::SMR000018616::N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]cyclopropanecarboxamide::N-[4-(3-methoxyphenyl)thiazol-2-yl]cyclopropanecarboxamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44773 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44773&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 4673629 252625379 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259081 O=C\C(=C/Nc1ccccn1)c1nc2ccccc2o1 InChI=1S/C15H11N3O2/c19-10-11(9-17-14-7-3-4-8-16-14)15-18-12-5-1-2-6-13(12)20-15/h1-10H,(H,16,17) GFXCWBFSVKWYQV-UHFFFAOYSA-N 128207 2-Benzooxazol-2-yl-3-(pyridin-2-ylamino)-propenal::(Z)-2-(1,3-benzoxazol-2-yl)-3-(pyridin-2-ylamino)prop-2-enal::SMR000115989::MLS000525515::cid_2249389::(Z)-2-(1,3-benzoxazol-2-yl)-3-(2-pyridinylamino)-2-propenal::(Z)-2-(1,3-benzoxazol-2-yl)-3-(2-pyridylamino)acrolein Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128207&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 2249389 225154550 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259082 Cc1cc(C)n(CC(=O)n2c(C)c(C)c3ccccc23)n1 InChI=1S/C17H19N3O/c1-11-9-12(2)19(18-11)10-17(21)20-14(4)13(3)15-7-5-6-8-16(15)20/h5-9H,10H2,1-4H3 LPAZGYYMDMKYAQ-UHFFFAOYSA-N 128208 1-(2,3-Dimethyl-indol-1-yl)-2-(3,5-dimethyl-pyrazol-1-yl)-ethanone::1-(2,3-dimethyl-1-indolyl)-2-(3,5-dimethyl-1-pyrazolyl)ethanone::SMR000117800::MLS000527326::cid_802846::1-(2,3-dimethylindol-1-yl)-2-(3,5-dimethylpyrazol-1-yl)ethanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128208 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128208&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 802846 225154551 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259083 Cc1ccc(\C=N\NC(=O)c2csc(C)c2)o1 InChI=1S/C12H12N2O2S/c1-8-3-4-11(16-8)6-13-14-12(15)10-5-9(2)17-7-10/h3-7H,1-2H3,(H,14,15) KJSRGXBMCZAIHI-UHFFFAOYSA-N 128209 5-methyl-N-[(E)-(5-methyl-2-furanyl)methylideneamino]-3-thiophenecarboxamide::SMR000115006::5-methyl-N'-[(5-methyl-2-furyl)methylene]-3-thiophenecarbohydrazide::5-methyl-N-[(E)-(5-methylfuran-2-yl)methylideneamino]thiophene-3-carboxamide::MLS000547835::cid_9563602::5-methyl-N-[(E)-(5-methyl-2-furyl)methyleneamino]thiophene-3-carboxamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128209&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 9563602 225154552 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259084 Cn1nccc1C(=O)N1CCc2ccccc12 InChI=1S/C13H13N3O/c1-15-12(6-8-14-15)13(17)16-9-7-10-4-2-3-5-11(10)16/h2-6,8H,7,9H2,1H3 QOLSCYHBYYZFNC-UHFFFAOYSA-N 128210 2,3-dihydroindol-1-yl-(2-methyl-3-pyrazolyl)methanone::SMR000114733::2,3-dihydroindol-1-yl-(2-methylpyrazol-3-yl)methanone::MLS000548512::cid_725789::1-[(1-methyl-1H-pyrazol-5-yl)carbonyl]indoline::indolin-1-yl-(2-methylpyrazol-3-yl)methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128210&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 725789 225154553 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259085 Cc1cccc(NC(c2ccc(O)cc2)c2ccc3ccc(C)nc3c2O)n1 InChI=1S/C23H21N3O2/c1-14-4-3-5-20(24-14)26-21(16-8-11-18(27)12-9-16)19-13-10-17-7-6-15(2)25-22(17)23(19)28/h3-13,21,27-28H,1-2H3,(H,24,26) GHAJWLCLZNLXNM-UHFFFAOYSA-N 128211 7-{(4-hydroxyphenyl)[(6-methyl-2-pyridinyl)amino]methyl}-2-methyl-8-quinolinol::MLS000530643::7-[(4-hydroxyphenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methyl-quinolin-8-ol::7-[(4-hydroxyphenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methylquinolin-8-ol::SMR000135621::cid_2895747::7-[(4-hydroxyphenyl)-[(6-methyl-2-pyridinyl)amino]methyl]-2-methyl-8-quinolinol::7-[(4-hydroxyphenyl)-[(6-methyl-2-pyridyl)amino]methyl]-2-methyl-quinolin-8-ol Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128211&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 2895747 225154554 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259086 CCOc1ccc(Nc2[nH]c(=O)sc2C=C2C=CC(=O)C=C2)cc1 |c:17,21,(3.08,-6.25,;3.08,-4.71,;4.41,-3.94,;4.41,-2.4,;3.08,-1.63,;3.08,-.09,;4.41,.68,;4.41,2.22,;5.75,2.99,;5.91,4.52,;7.41,4.84,;8.04,6.25,;8.18,3.51,;7.15,2.36,;7.47,.86,;8.94,.38,;9.26,-1.12,;10.72,-1.6,;11.87,-.57,;13.33,-1.05,;11.55,.94,;10.08,1.41,;5.75,-.09,;5.75,-1.63,)| InChI=1S/C18H16N2O3S/c1-2-23-15-9-5-13(6-10-15)19-17-16(24-18(22)20-17)11-12-3-7-14(21)8-4-12/h3-11,19H,2H2,1H3,(H,20,22) ZAQATKVCKANQIU-UHFFFAOYSA-N 50091 SMR000145427::cid_5398488::4-[(E)-4-Ethoxy-phenylimino]-5-[1-(4-hydroxy-phenyl)-meth-(Z)-ylidene]-thiazolidin-2-one::MLS000551502::4-[(4-ethoxyphenyl)amino]-5-[(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)methyl]-3H-1,3-thiazol-2-one::4-(4-ethoxyanilino)-5-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3H-1,3-thiazol-2-one::4-(4-ethoxyanilino)-5-[(4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-3H-thiazol-2-one::5-[(4-ketocyclohexa-2,5-dien-1-ylidene)methyl]-4-(p-phenetidino)-4-thiazolin-2-one Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5398488 252630362 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259087 Cc1cnc(NC(=O)CCCc2nc3ccccc3s2)s1 InChI=1S/C15H15N3OS2/c1-10-9-16-15(20-10)18-13(19)7-4-8-14-17-11-5-2-3-6-12(11)21-14/h2-3,5-6,9H,4,7-8H2,1H3,(H,16,18,19) MWYJTJSJYKOZSD-UHFFFAOYSA-N 96956 4-(1,3-benzothiazol-2-yl)-N-(5-methyl-1,3-thiazol-2-yl)butanamide::MLS000568842::SMR000154827::4-(1,3-benzothiazol-2-yl)-N-(5-methyl-2-thiazolyl)butanamide::cid_2445782::4-(1,3-benzothiazol-2-yl)-N-(5-methylthiazol-2-yl)butyramide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96956 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96956&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 2445782 164038200 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259088 OC(=O)c1ccc(CSc2nnc(Cc3ccccc3)o2)cc1 InChI=1S/C17H14N2O3S/c20-16(21)14-8-6-13(7-9-14)11-23-17-19-18-15(22-17)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,20,21) GZKSOFCRKSPIPX-UHFFFAOYSA-N 128212 4-[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]benzoic acid::SMR000136489::4-{[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]methyl}benzoic acid::4-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzoic acid::cid_1249904::MLS000531511::4-[[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]thio]methyl]benzoic acid::4-[[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]methyl]benzoic acid Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128212&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 1249904 225154555 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259089 CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C19H15ClN2O3S/c1-2-25-19(24)22-18-21-15(12-6-4-3-5-7-12)17(26-18)16(23)13-8-10-14(20)11-9-13/h3-11H,2H2,1H3,(H,21,22,24) QLDONWGCRXGAIQ-UHFFFAOYSA-N 50308499 CHEMBL602722::cid_7315332::Ethyl 5-(4-chlorobenzoyl)-4-phenylthiazol-2-ylcarbamate Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308499&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 7315332 104162860 CHEMBL602722 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259090 CCn1ncc(\C=N/NC(=O)c2csc3ccccc23)c1C InChI=1S/C16H16N4OS/c1-3-20-11(2)12(9-18-20)8-17-19-16(21)14-10-22-15-7-5-4-6-13(14)15/h4-10H,3H2,1-2H3,(H,19,21) TWVYSMOHNATQJB-UHFFFAOYSA-N 128213 N-[(Z)-(1-ethyl-5-methyl-pyrazol-4-yl)methylideneamino]-1-benzothiophene-3-carboxamide::SMR000159916::N'-[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methylene]-1-benzothiophene-3-carbohydrazide::MLS000545606::N-[(Z)-(1-ethyl-5-methyl-4-pyrazolyl)methylideneamino]-1-benzothiophene-3-carboxamide::cid_5412241::N-[(Z)-(1-ethyl-5-methylpyrazol-4-yl)methylideneamino]-1-benzothiophene-3-carboxamide::N-[(Z)-(1-ethyl-5-methyl-pyrazol-4-yl)methyleneamino]benzothiophene-3-carboxamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128213&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5412241 225154556 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259091 Cc1ccc(o1)C1CC(=NN1C(=S)Nc1ccccc1)c1ccccc1 |c:9| InChI=1S/C21H19N3OS/c1-15-12-13-20(25-15)19-14-18(16-8-4-2-5-9-16)23-24(19)21(26)22-17-10-6-3-7-11-17/h2-13,19H,14H2,1H3,(H,22,26) NRMHIDNCTRDDRQ-UHFFFAOYSA-N 128214 5-(5-methyl-2-furyl)-N,3-diphenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide::SMR000161361::MLS000325293::cid_11841141::3-(5-methylfuran-2-yl)-N,5-diphenyl-3,4-dihydropyrazole-2-carbothioamide::3-(5-methyl-2-furanyl)-N,5-diphenyl-3,4-dihydropyrazole-2-carbothioamide::5-(5-methyl-2-furyl)-N,3-diphenyl-2-pyrazoline-1-carbothioamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128214&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 11841141 225154557 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259092 Cl.NC(=O)NC(=O)Cn1ccc(=N)c2ccccc12 InChI=1S/C12H12N4O2.ClH/c13-9-5-6-16(7-11(17)15-12(14)18)10-4-2-1-3-8(9)10;/h1-6,13H,7H2,(H3,14,15,17,18);1H NRIMZRLYRFVYLP-UHFFFAOYSA-N 128215 N-aminocarbonyl-2-(4-azanylidenequinolin-1-yl)ethanamide;hydrochloride::MLS000595230::N-carbamoyl-2-(4-imino-1-quinolinyl)acetamide;hydrochloride::N-carbamoyl-2-(4-iminoquinolin-1-yl)acetamide;hydrochloride::cid_11957159::[2-(4-Imino-4H-quinolin-1-yl)-acetyl]-urea::SMR000149753::N-carbamoyl-2-(4-imino-1-quinolyl)acetamide;hydrochloride Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128215 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128215&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 919914 225154558 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259093 Cc1ccc(CNC(=O)Cc2ccc(cc2)-c2ccccc2)cc1 InChI=1S/C22H21NO/c1-17-7-9-19(10-8-17)16-23-22(24)15-18-11-13-21(14-12-18)20-5-3-2-4-6-20/h2-14H,15-16H2,1H3,(H,23,24) RCSDXYYRTBCJNB-UHFFFAOYSA-N 128216 N-[(4-methylphenyl)methyl]-2-(4-phenylphenyl)ethanamide::N-[(4-methylphenyl)methyl]-2-(4-phenylphenyl)acetamide::2-(4-biphenylyl)-N-(4-methylbenzyl)acetamide::SMR000198074::cid_2185046::MLS000576794::N-(4-methylbenzyl)-2-(4-phenylphenyl)acetamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128216 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128216&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 2185046 225154559 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259094 COc1ccc2cc3c(N)nn(C(=O)c4ccccc4[N+]([O-])=O)c3nc2c1 InChI=1S/C18H13N5O4/c1-27-11-7-6-10-8-13-16(19)21-22(17(13)20-14(10)9-11)18(24)12-4-2-3-5-15(12)23(25)26/h2-9H,1H3,(H2,19,21) VHVJCLWOXHRPDC-UHFFFAOYSA-N 128217 7-methoxy-1-(2-nitrobenzoyl)-1H-pyrazolo[3,4-b]quinolin-3-amine::(3-amino-7-methoxypyrazolo[3,4-b]quinolin-1-yl)-(2-nitrophenyl)methanone::SMR000206462::MLS000582476::cid_12004547::(3-azanyl-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-(2-nitrophenyl)methanone::(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-(2-nitrophenyl)methanone::(3-amino-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-(2-nitrophenyl)methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128217&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 12004547 225154560 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259095 COc1ccc2[nH]c3c(Cl)ncnc3c2c1 InChI=1S/C11H8ClN3O/c1-16-6-2-3-8-7(4-6)9-10(15-8)11(12)14-5-13-9/h2-5,15H,1H3 GFJIJJZNYCWNGS-UHFFFAOYSA-N 128218 4-chloranyl-8-methoxy-5H-pyrimido[5,4-b]indole::cid_5399944::4-chloro-8-methoxy-5H-pyrimido[5,4-b]indole::1-Chloro-6-methoxy-9H-2,4,9-triaza-fluorene::MLS000559714::SMR000174930::4-chloro-8-methoxy-5H-pyrimid[5,4-b]indole Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128218 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128218&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5399944 225154561 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259096 Cn1cc(C2CC(=NN2C(=O)c2ccccc2)c2ccccc2)c2ccccc12 |c:6| InChI=1S/C25H21N3O/c1-27-17-21(20-14-8-9-15-23(20)27)24-16-22(18-10-4-2-5-11-18)26-28(24)25(29)19-12-6-3-7-13-19/h2-15,17,24H,16H2,1H3 OQINTNFCGFASMS-UHFFFAOYSA-N 128219 SMR000212528::[3-(1-methyl-3-indolyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-phenylmethanone::MLS000588879::[3-(1-methylindol-3-yl)-5-phenyl-3,4-dihydropyrazol-2-yl]-phenylmethanone::[5-(1-Methyl-1H-indol-3-yl)-3-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl-methanone::cid_3814317::[3-(1-methylindol-3-yl)-5-phenyl-3,4-dihydropyrazol-2-yl]-phenyl-methanone::[5-(1-methylindol-3-yl)-3-phenyl-2-pyrazolin-1-yl]-phenyl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128219&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 3814317 225154562 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259097 Cc1c(NS(=O)(=O)c2ccc(NC3CCCC3)c(c2)[N+]([O-])=O)c(=O)n(-c2ccccc2)n1C InChI=1S/C22H25N5O5S/c1-15-21(22(28)26(25(15)2)17-10-4-3-5-11-17)24-33(31,32)18-12-13-19(20(14-18)27(29)30)23-16-8-6-7-9-16/h3-5,10-14,16,23-24H,6-9H2,1-2H3 PBPRTRGITUJLKP-UHFFFAOYSA-N 128220 MLS000393676::SMR000241429::4-(cyclopentylamino)-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-3-nitro-benzenesulfonamide::4-(cyclopentylamino)-N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-nitrobenzenesulfonamide::4-(cyclopentylamino)-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-nitrobenzenesulfonamide::cid_4681574::4-(cyclopentylamino)-N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-3-nitro-benzenesulfonamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128220 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128220&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 4681574 225154563 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259098 Cc1c(cnn1C)C(=O)N1CCc2ccccc12 InChI=1S/C14H15N3O/c1-10-12(9-15-16(10)2)14(18)17-8-7-11-5-3-4-6-13(11)17/h3-6,9H,7-8H2,1-2H3 IONFENJMUKPATL-UHFFFAOYSA-N 128221 2,3-dihydroindol-1-yl-(1,5-dimethylpyrazol-4-yl)methanone::SMR000227824::2,3-dihydroindol-1-yl-(1,5-dimethyl-4-pyrazolyl)methanone::MLS000698295::cid_1225706::1-[(1,5-dimethyl-1H-pyrazol-4-yl)carbonyl]indoline::(1,5-dimethylpyrazol-4-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128221&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 1225706 225154564 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259099 Cc1nn(C)c(C(=O)N2CCc3ccccc23)c1Br InChI=1S/C14H14BrN3O/c1-9-12(15)13(17(2)16-9)14(19)18-8-7-10-5-3-4-6-11(10)18/h3-6H,7-8H2,1-2H3 SDCXDURISJTESF-UHFFFAOYSA-N 69068 SMR000228334::(4-bromanyl-2,5-dimethyl-pyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::cid_844740::MLS000698064::(4-bromo-2,5-dimethyl-3-pyrazolyl)-(2,3-dihydroindol-1-yl)methanone::1-[(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]indoline::(4-bromo-2,5-dimethylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::(4-bromo-2,5-dimethyl-pyrazol-3-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69068 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69068&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 844740 252647240 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259100 Cn1cc(Br)c(n1)C(=O)N1CCc2ccccc12 InChI=1S/C13H12BrN3O/c1-16-8-10(14)12(15-16)13(18)17-7-6-9-4-2-3-5-11(9)17/h2-5,8H,6-7H2,1H3 WJIZIAAAYGEXMI-UHFFFAOYSA-N 128222 1-[(4-bromo-1-methyl-1H-pyrazol-3-yl)carbonyl]indoline::MLS000703851::(4-bromanyl-1-methyl-pyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::cid_903405::(4-bromo-1-methyl-3-pyrazolyl)-(2,3-dihydroindol-1-yl)methanone::(4-bromo-1-methylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::SMR000227233::(4-bromo-1-methyl-pyrazol-3-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128222 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128222&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 903405 225154565 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259101 Cn1ncc(Br)c1C(=O)N1CCc2ccccc12 InChI=1S/C13H12BrN3O/c1-16-12(10(14)8-15-16)13(18)17-7-6-9-4-2-3-5-11(9)17/h2-5,8H,6-7H2,1H3 IHCMZNYXIASBGZ-UHFFFAOYSA-N 128223 SMR000227173::(4-bromanyl-2-methyl-pyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::(4-bromo-2-methyl-3-pyrazolyl)-(2,3-dihydroindol-1-yl)methanone::cid_903067::(4-bromo-2-methylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::MLS000704145::1-[(4-bromo-1-methyl-1H-pyrazol-5-yl)carbonyl]indoline::(4-bromo-2-methyl-pyrazol-3-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128223 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128223&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 903067 225154566 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259102 Cc1c(Br)c(nn1C)C(=O)N1CCc2ccccc12 InChI=1S/C14H14BrN3O/c1-9-12(15)13(16-17(9)2)14(19)18-8-7-10-5-3-4-6-11(10)18/h3-6H,7-8H2,1-2H3 XLZNIZTWUFBIBN-UHFFFAOYSA-N 128224 (4-bromo-1,5-dimethylpyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::MLS000703931::cid_844287::SMR000228289::(4-bromo-1,5-dimethyl-3-pyrazolyl)-(2,3-dihydroindol-1-yl)methanone::1-[(4-bromo-1,5-dimethyl-1H-pyrazol-3-yl)carbonyl]indoline::(4-bromanyl-1,5-dimethyl-pyrazol-3-yl)-(2,3-dihydroindol-1-yl)methanone::(4-bromo-1,5-dimethyl-pyrazol-3-yl)-indolin-1-yl-methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128224 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128224&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 844287 225154567 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259103 Oc1cc(=O)[nH]c2nc(Nc3ccc(Cl)c(F)c3)sc12 InChI=1S/C12H7ClFN3O2S/c13-6-2-1-5(3-7(6)14)15-12-17-11-10(20-12)8(18)4-9(19)16-11/h1-4H,(H3,15,16,17,18,19) HPWJLFZZVAHRFO-UHFFFAOYSA-N 128225 MLS000332377::2-(4-chloro-3-fluoroanilino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one::2-[(4-chloranyl-3-fluoranyl-phenyl)amino]-7-oxidanyl-4H-[1,3]thiazolo[4,5-b]pyridin-5-one::cid_54677165::SMR000221708::2-(4-Chloro-3-fluoro-phenylamino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one::2-(4-chloro-3-fluoroanilino)-7-hydroxy-4H-[1,3]thiazolo[4,5-b]pyridin-5-one::2-(4-chloro-3-fluoro-anilino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128225 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128225&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 75668684 225154568 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259104 CC(=O)c1cc(C(C)=O)c(C)nc1C InChI=1S/C11H13NO2/c1-6-10(8(3)13)5-11(9(4)14)7(2)12-6/h5H,1-4H3 RCACBGGDSKMOCT-UHFFFAOYSA-N 128226 1-(5-ethanoyl-2,6-dimethyl-pyridin-3-yl)ethanone::cid_540145::1-(5-acetyl-2,6-dimethylpyridin-3-yl)ethanone::1-(5-acetyl-2,6-dimethyl-3-pyridinyl)ethanone::SMR000279633::MLS000765927::1-(5-acetyl-2,6-dimethyl-3-pyridyl)ethanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128226&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 540145 225154569 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259105 OCCNc1c2ccccc2nc2ccccc12 InChI=1S/C15H14N2O/c18-10-9-16-15-11-5-1-3-7-13(11)17-14-8-4-2-6-12(14)15/h1-8,18H,9-10H2,(H,16,17) FGDNLOYCZDEEQP-UHFFFAOYSA-N 74979 SMR000281941::cid_145758::MLS000712174::2-(9-acridinylamino)ethanol::2-(acridin-9-ylamino)ethanol Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=74979 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=74979&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 145758 252652197 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259106 CC(Oc1ccccc1)C(=O)N1CCN=C1SCc1ccccc1 |c:15| InChI=1S/C19H20N2O2S/c1-15(23-17-10-6-3-7-11-17)18(22)21-13-12-20-19(21)24-14-16-8-4-2-5-9-16/h2-11,15H,12-14H2,1H3 MYKAEFIROSUYOL-UHFFFAOYSA-N 66579 1-(2-benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-phenoxypropan-1-one::2-phenoxy-1-[2-(phenylmethylsulfanyl)-4,5-dihydroimidazol-1-yl]propan-1-one::2-phenoxy-1-[2-(phenylmethylthio)-4,5-dihydroimidazol-1-yl]-1-propanone::MLS000684685::SMR000323191::cid_4558613::1-[2-(benzylthio)-2-imidazolin-1-yl]-2-phenoxy-propan-1-one Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66579 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66579&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 4558613 252644900 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259107 CN(C)\C=C\c1nc(SCc2ccc(Cl)cc2)nnc1C InChI=1S/C15H17ClN4S/c1-11-14(8-9-20(2)3)17-15(19-18-11)21-10-12-4-6-13(16)7-5-12/h4-9H,10H2,1-3H3 RHBYHXLJTKFAOR-UHFFFAOYSA-N 128227 cid_6404717::(E)-2-[3-[(4-chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]-N,N-dimethylethenamine::MLS000721513::(E)-2-{3-[(4-chlorobenzyl)sulfanyl]-6-methyl-1,2,4-triazin-5-yl}-N,N-dimethyl-1-ethenamine::(E)-2-[3-[(4-chlorophenyl)methylthio]-6-methyl-1,2,4-triazin-5-yl]-N,N-dimethylethenamine::SMR000337144::(E)-2-[3-[(4-chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]-N,N-dimethyl-ethenamine::[(E)-2-[3-[(4-chlorobenzyl)thio]-6-methyl-1,2,4-triazin-5-yl]vinyl]-dimethyl-amine Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128227 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128227&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 6404717 225154570 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259108 [O-]\C(=C(/C(=S)Nc1ccc(SC(F)F)cc1)[n+]1ccccc1)c1cc(Cl)ccc1Cl InChI=1S/C21H14Cl2F2N2OS2/c22-13-4-9-17(23)16(12-13)19(28)18(27-10-2-1-3-11-27)20(29)26-14-5-7-15(8-6-14)30-21(24)25/h1-12,21H,(H-,26,28,29) NLKBMPCLHRUFGE-UHFFFAOYSA-N 128228 SMR000349628::cid_16195927::MLS001006684::(E)-1-[2,5-bis(chloranyl)phenyl]-3-[[4-[bis(fluoranyl)methylsulfanyl]phenyl]amino]-2-pyridin-1-ium-1-yl-3-sulfanylidene-prop-1-en-1-olate::(E)-1-(2,5-dichlorophenyl)-3-[4-(difluoromethylsulfanyl)anilino]-2-pyridin-1-ium-1-yl-3-sulfanylideneprop-1-en-1-olate::(E)-1-(2,5-dichlorophenyl)-3-[4-(difluoromethylthio)anilino]-2-(1-pyridin-1-iumyl)-3-sulfanylidene-1-propen-1-olate::(E)-1-(2,5-dichlorophenyl)-3-[4-(difluoromethylthio)anilino]-2-pyridin-1-ium-1-yl-3-thioxo-prop-1-en-1-olate Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128228 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128228&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 16195927 225154571 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259109 CC(C)CNC(=O)CSc1nnc2ccccn12 InChI=1S/C12H16N4OS/c1-9(2)7-13-11(17)8-18-12-15-14-10-5-3-4-6-16(10)12/h3-6,9H,7-8H2,1-2H3,(H,13,17) JQTWRFZIZVVMRG-UHFFFAOYSA-N 128229 cid_4882475::N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)acetamide::SMR000344677::N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)acetamide::N-(2-methylpropyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanyl)ethanamide::MLS000772677::N-isobutyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)acetamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128229 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128229&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 4882475 225154572 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259110 [O-][N+](=O)c1cccc(c1)-c1noc(n1)-c1ccco1 InChI=1S/C12H7N3O4/c16-15(17)9-4-1-3-8(7-9)11-13-12(19-14-11)10-5-2-6-18-10/h1-7H ZYYUAFAEJZYDNR-UHFFFAOYSA-N 128230 cid_699740::5-(2-furanyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole::5-(furan-2-yl)-3-(3-nitrophenyl)-1,2,4-oxadiazole::SMR000435927::MLS000332632::5-Furan-2-yl-3-(3-nitro-phenyl)-[1,2,4]oxadiazole::5-(2-furyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128230&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 699740 225154573 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259111 CN1C(=O)N(C)C(=O)C(=Cc2[nH]c3ccccc3c2CCNC(=S)NC2CC2)C1=O |(14.98,-2.98,;13.64,-3.75,;13.64,-5.29,;14.98,-6.06,;12.31,-6.06,;12.31,-7.6,;10.98,-5.29,;9.64,-6.06,;10.98,-3.75,;9.64,-2.98,;8.1,-2.98,;7.2,-4.22,;5.75,-3.75,;4.41,-4.52,;3.08,-3.75,;3.08,-2.21,;4.41,-1.44,;5.75,-2.21,;7.2,-1.74,;7.68,-.27,;6.65,.87,;7.13,2.34,;6.1,3.48,;4.6,3.16,;6.58,4.94,;5.55,6.09,;5.24,7.6,;4.09,6.57,;12.31,-2.98,;12.31,-1.44,)| InChI=1S/C21H23N5O3S/c1-25-18(27)15(19(28)26(2)21(25)29)11-17-14(13-5-3-4-6-16(13)24-17)9-10-22-20(30)23-12-7-8-12/h3-6,11-12,24H,7-10H2,1-2H3,(H2,22,23,30) KAOMWIDMUPJQOK-UHFFFAOYSA-N 55866 MLS000332961::cid_5620224::1-cyclopropyl-3-[2-[2-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1H-indol-3-yl]ethyl]thiourea::1-cyclopropyl-3-[2-[2-[[1,3-dimethyl-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]-1H-indol-3-yl]ethyl]thiourea::SMR000436309::1-Cyclopropyl-3-{2-[2-(1,3-dimethyl-2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-1H-indol-3-yl]-eth yl}-thiourea::1-cyclopropyl-3-[2-[2-[(2,4,6-triketo-1,3-dimethyl-hexahydropyrimidin-5-ylidene)methyl]-1H-indol-3-yl]ethyl]thiourea Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55866 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55866&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5620224 252635851 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259112 Cl.COc1ccc(CCNc2c3ccccc3nc3ccccc23)cc1OC InChI=1S/C23H22N2O2.ClH/c1-26-21-12-11-16(15-22(21)27-2)13-14-24-23-17-7-3-5-9-19(17)25-20-10-6-4-8-18(20)23;/h3-12,15H,13-14H2,1-2H3,(H,24,25);1H FKAYXVNHYWCNSJ-UHFFFAOYSA-N 128231 N-[2-(3,4-dimethoxyphenyl)ethyl]acridin-9-amine;hydrochloride::Acridin-9-yl-[2-(3,4-dimethoxy-phenyl)-ethyl]-amine::MLS000768230::cid_16682491::N-[2-(3,4-dimethoxyphenyl)ethyl]-9-acridinamine;hydrochloride::SMR000431551::acridin-9-yl(homoveratryl)amine;hydrochloride Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128231 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128231&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 3815572 225154574 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259113 COc1ccc(cc1OC)-c1noc(n1)-c1cccs1 InChI=1S/C14H12N2O3S/c1-17-10-6-5-9(8-11(10)18-2)13-15-14(19-16-13)12-4-3-7-20-12/h3-8H,1-2H3 QVNVLXWIMKMRFP-UHFFFAOYSA-N 128232 3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole::SMR000437691::MLS000333489::3-(3,4-Dimethoxy-phenyl)-5-thiophen-2-yl-[1,2,4]oxadiazole::cid_1221653::3-(3,4-dimethoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128232 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128232&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 1221653 225154575 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259114 CCCCN1C(=O)NC(=O)\C(=C(\O)/C=C/c2ccc3OCOc3c2)C1=O InChI=1S/C18H18N2O6/c1-2-3-8-20-17(23)15(16(22)19-18(20)24)12(21)6-4-11-5-7-13-14(9-11)26-10-25-13/h4-7,9,21H,2-3,8,10H2,1H3,(H,19,22,24) KQDDWXNOHKMGJJ-UHFFFAOYSA-N 128233 (5Z)-5-[(E)-3-(1,3-benzodioxol-5-yl)-1-oxidanyl-prop-2-enylidene]-1-butyl-1,3-diazinane-2,4,6-trione::SMR000439468::MLS000763033::cid_54677751::(5Z)-5-[(E)-3-(1,3-benzodioxol-5-yl)-1-hydroxyprop-2-enylidene]-1-butyl-1,3-diazinane-2,4,6-trione::5-((E)-3-Benzo[1,3]dioxol-5-yl-acryloyl)-3-butyl-6-hydroxy-1H-pyrimidine-2,4-dione::(5Z)-5-[(E)-3-(1,3-benzodioxol-5-yl)-1-hydroxy-prop-2-enylidene]-1-butyl-barbituric acid Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128233 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128233&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 54677751 225154576 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259115 C\C(=N/Nc1ncc(Br)cn1)c1cccc(c1)[N+]([O-])=O InChI=1S/C12H10BrN5O2/c1-8(9-3-2-4-11(5-9)18(19)20)16-17-12-14-6-10(13)7-15-12/h2-7H,1H3,(H,14,15,17) PMXWENWUNMFZEF-UHFFFAOYSA-N 128234 SMR000513413::5-bromo-N-[(E)-1-(3-nitrophenyl)ethylideneamino]pyrimidin-2-amine::N-(5-Bromo-pyrimidin-2-yl)-N'-[1-(3-nitro-phenyl)-ethylidene]-hydrazine::cid_5338790::MLS001211234::5-bromanyl-N-[(E)-1-(3-nitrophenyl)ethylideneamino]pyrimidin-2-amine::5-bromo-N-[(E)-1-(3-nitrophenyl)ethylideneamino]-2-pyrimidinamine::(5-bromopyrimidin-2-yl)-[(E)-1-(3-nitrophenyl)ethylideneamino]amine Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128234 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128234&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 5338790 225154577 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259116 CN(C)CC(CCC(CN(C)C)C(O)(c1ccccc1)c1ccccc1)C(O)(c1ccccc1)c1ccccc1 InChI=1S/C36H44N2O2/c1-37(2)27-33(35(39,29-17-9-5-10-18-29)30-19-11-6-12-20-30)25-26-34(28-38(3)4)36(40,31-21-13-7-14-22-31)32-23-15-8-16-24-32/h5-24,33-34,39-40H,25-28H2,1-4H3 KFEZGJFTVICLIJ-UHFFFAOYSA-N 128235 cid_3781244::MLS001173677::2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenylhexane-1,6-diol::SMR000538747::2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenyl-hexane-1,6-diol Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128235 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128235&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 3781244 225154578 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259117 ClCC(=O)c1cc2CC(=O)N3CCCc(c1)c23 InChI=1S/C13H12ClNO2/c14-7-11(16)9-4-8-2-1-3-15-12(17)6-10(5-9)13(8)15/h4-5H,1-3,6-7H2 KRFPREPGGHPLOB-UHFFFAOYSA-N 128236 MLS001175628::SMR000595850::cid_4962642 Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128236 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128236&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 4962642 252664614 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259118 CC1CN(Cc2ccccc2)c2nc3n(C)c(=O)n(CC=C)c(=O)c3n2C1 InChI=1S/C20H23N5O2/c1-4-10-24-18(26)16-17(22(3)20(24)27)21-19-23(11-14(2)12-25(16)19)13-15-8-6-5-7-9-15/h4-9,14H,1,10-13H2,2-3H3 NIBNFDNRFDBJOY-UHFFFAOYSA-N 128237 SMR000641396::MLS001166754::cid_6484568::9-benzyl-1,7-dimethyl-3-prop-2-enyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione::1,7-dimethyl-9-(phenylmethyl)-3-prop-2-enyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione::3-allyl-9-benzyl-1,7-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-quinone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128237 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128237&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 74687657 225154579 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259119 CC1CN(Cc2ccccc2)c2nc3n(C)c(=O)n(CC(N)=O)c(=O)c3n2C1 InChI=1S/C19H22N6O3/c1-12-8-23(10-13-6-4-3-5-7-13)18-21-16-15(24(18)9-12)17(27)25(11-14(20)26)19(28)22(16)2/h3-7,12H,8-11H2,1-2H3,(H2,20,26) QGQZPDJXRYUODM-UHFFFAOYSA-N 128238 2-(9-benzyl-1,7-dimethyl-2,4-dioxo-7,8-dihydro-6H-purino[7,8-a]pyrimidin-3-yl)acetamide::2-[1,7-dimethyl-2,4-dioxo-9-(phenylmethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidin-3-yl]acetamide::2-[1,7-dimethyl-2,4-bis(oxidanylidene)-9-(phenylmethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidin-3-yl]ethanamide::cid_16614245::SMR000641393::MLS001166760::2-(9-benzyl-2,4-diketo-1,7-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidin-3-yl)acetamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128238 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128238&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 86766748 225154580 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259120 COc1ccc(cc1S(=O)(=O)NCc1cccc(C)c1)-c1cc(C)no1 InChI=1S/C19H20N2O4S/c1-13-5-4-6-15(9-13)12-20-26(22,23)19-11-16(7-8-17(19)24-3)18-10-14(2)21-25-18/h4-11,20H,12H2,1-3H3 XHRNPZWYUMMIET-UHFFFAOYSA-N 94271 SMR000630399::MLS001095083::2-methoxy-5-(3-methyl-1,2-oxazol-5-yl)-N-[(3-methylphenyl)methyl]benzenesulfonamide::cid_20936139::2-methoxy-5-(3-methyl-5-isoxazolyl)-N-[(3-methylphenyl)methyl]benzenesulfonamide::2-methoxy-N-(3-methylbenzyl)-5-(3-methylisoxazol-5-yl)benzenesulfonamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94271 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94271&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 20936139 164035515 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259121 CN(Cc1ccccc1)C(=O)c1[nH]cnc1C(=O)NCC(=O)OC(C)(C)C InChI=1S/C19H24N4O4/c1-19(2,3)27-14(24)10-20-17(25)15-16(22-12-21-15)18(26)23(4)11-13-8-6-5-7-9-13/h5-9,12H,10-11H2,1-4H3,(H,20,25)(H,21,22) WNLCBEGUWODQIA-UHFFFAOYSA-N 128239 2-[[[5-[[methyl-(phenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]acetic acid tert-butyl ester::cid_24792918::tert-butyl 2-[[5-[benzyl(methyl)carbamoyl]-1H-imidazole-4-carbonyl]amino]acetate::ILP-II-126::SMR000642004::MLS000911322::tert-butyl 2-[[5-[methyl-(phenylmethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]ethanoate::2-[[5-[benzyl(methyl)carbamoyl]-1H-imidazole-4-carbonyl]amino]acetic acid tert-butyl ester Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128239 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128239&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 24792918 225154581 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259122 CCCNC(=O)c1ccc(N2CCC3(CC(=NO3)c3ccccc3)CC2)c(NC(=O)c2ccco2)c1 |c:15| InChI=1S/C28H30N4O4/c1-2-14-29-26(33)21-10-11-24(22(18-21)30-27(34)25-9-6-17-35-25)32-15-12-28(13-16-32)19-23(31-36-28)20-7-4-3-5-8-20/h3-11,17-18H,2,12-16,19H2,1H3,(H,29,33)(H,30,34) PKVPEEZSVNQUNO-UHFFFAOYSA-N 58653 SMR000718491::cid_24816792::MLS001074376::N-[2-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)-5-(propylcarbamoyl)phenyl]furan-2-carboxamide::N-[5-[oxo(propylamino)methyl]-2-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)phenyl]-2-furancarboxamide::N-[2-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)-5-(propylcarbamoyl)phenyl]-2-furamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=58653 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=58653&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 24816792 252638470 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259123 COc1ccc(C(=O)NC2CCCc3c2cnn3-c2cc(F)cc(F)c2)c(OC)c1OC InChI=1S/C23H23F2N3O4/c1-30-20-8-7-16(21(31-2)22(20)32-3)23(29)27-18-5-4-6-19-17(18)12-26-28(19)15-10-13(24)9-14(25)11-15/h7-12,18H,4-6H2,1-3H3,(H,27,29) XJSLGFLEWBJOQG-UHFFFAOYSA-N 128240 cid_24817766::MLS001124677::N-[1-[3,5-bis(fluoranyl)phenyl]-4,5,6,7-tetrahydroindazol-4-yl]-2,3,4-trimethoxy-benzamide::N-[1-(3,5-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,3,4-trimethoxybenzamide::SMR000653637::N-[1-(3,5-difluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,3,4-trimethoxy-benzamide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128240 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128240&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 24817766 225154582 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259124 CN(c1cccc(C)c1C)c1ncnc2onc(-c3ccc(F)cc3)c12 InChI=1S/C20H17FN4O/c1-12-5-4-6-16(13(12)2)25(3)19-17-18(14-7-9-15(21)10-8-14)24-26-20(17)23-11-22-19/h4-11H,1-3H3 UYFDAWJDOCPZLH-UHFFFAOYSA-N 128241 MLS001143290::N-(2,3-dimethylphenyl)-3-(4-fluorophenyl)-N-methyl-4-isoxazolo[5,4-d]pyrimidinamine::SMR000796266::N-(2,3-dimethylphenyl)-3-(4-fluorophenyl)-N-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-amine::cid_24856208::(2,3-dimethylphenyl)-[3-(4-fluorophenyl)isoxazolo[5,4-d]pyrimidin-4-yl]-methyl-amine Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128241 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128241&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 24856208 225154583 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259125 COc1ccc(cc1)[C@@H]1CC=C([C@@H](N1S(=O)(=O)c1ccccc1C)c1ccccc1F)C(O)=O |c:11| InChI=1S/C26H24FNO5S/c1-17-7-3-6-10-24(17)34(31,32)28-23(18-11-13-19(33-2)14-12-18)16-15-21(26(29)30)25(28)20-8-4-5-9-22(20)27/h3-15,23,25H,16H2,1-2H3,(H,29,30) YYHXIOWLHKLCJP-UHFFFAOYSA-N 128242 SMR001261527::cid_25102606::(2S,6R)-6-(2-fluorophenyl)-2-(4-methoxyphenyl)-1-(2-methylphenyl)sulfonyl-3,6-dihydro-2H-pyridine-5-carboxylic acid::MLS002174361::(2S,6R)-6-(2-fluorophenyl)-2-(4-methoxyphenyl)-1-(o-tolylsulfonyl)-3,6-dihydro-2H-pyridine-5-carboxylic acid Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128242 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128242&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 25102606 225154584 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259126 CCCC(=O)NC1=C(N2CC2)C(=O)C(NC(=O)CCC)=C(N2CC2)C1=O |c:6,t:20| InChI=1S/C18H24N4O4/c1-3-5-11(23)19-13-15(21-7-8-21)18(26)14(20-12(24)6-4-2)16(17(13)25)22-9-10-22/h3-10H2,1-2H3,(H,19,23)(H,20,24) NXGVCPVLNVWSJF-UHFFFAOYSA-N 128243 N-[2,5-bis(aziridin-1-yl)-4-(butanoylamino)-3,6-dioxocyclohexa-1,4-dien-1-yl]butanamide::cid_227091::N-[2,5-bis(1-aziridinyl)-3,6-dioxo-4-(1-oxobutylamino)-1-cyclohexa-1,4-dienyl]butanamide::SMR001548060::NSC 18274::MLS002638588::N-[2,5-bis(aziridin-1-yl)-4-(butanoylamino)-3,6-bis(oxidanylidene)cyclohexa-1,4-dien-1-yl]butanamide::N-(4-butyramido-2,5-diethylenimino-3,6-diketo-cyclohexa-1,4-dien-1-yl)butyramide Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128243 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128243&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 227091 225154585 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259127 CN(C)CCNc1ccc(CO)c2oc3ccc(O)cc3c(=O)c12 InChI=1S/C18H20N2O4/c1-20(2)8-7-19-14-5-3-11(10-21)18-16(14)17(23)13-9-12(22)4-6-15(13)24-18/h3-6,9,19,21-22H,7-8,10H2,1-2H3 BOTXZPXSICDQHE-UHFFFAOYSA-N 94854 SMR001566706::MLS002702888::1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)xanthen-9-one::9H-Xanthen-9-one, 1-[[2-(dimethylamino)ethyl]amino]- 7-hydroxy-4-(hydroxymethyl)-::cid_337396::1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)-9-xanthenone::1-[2-(dimethylamino)ethylamino]-4-(hydroxymethyl)-7-oxidanyl-xanthen-9-one::1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-methylol-xanthone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94854 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94854&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 337396 164036098 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259128 Cc1ccc(cc1)[C@H]1C[C@@H](O)[C@@H](CN1C(=O)c1cccs1)n1cc(nn1)-c1ccc(F)cc1 InChI=1S/C25H23FN4O2S/c1-16-4-6-18(7-5-16)21-13-23(31)22(15-29(21)25(32)24-3-2-12-33-24)30-14-20(27-28-30)17-8-10-19(26)11-9-17/h2-12,14,21-23,31H,13,15H2,1H3 UTGCTLYSNFFEBO-UHFFFAOYSA-N 128244 MLS003116436::KUC104959::cid_46903185::[(2R,4R,5R)-5-[4-(4-fluorophenyl)triazol-1-yl]-4-hydroxy-2-(4-methylphenyl)piperidin-1-yl]-thiophen-2-ylmethanone::[(2R,4R,5R)-5-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-2-(4-methylphenyl)-4-oxidanyl-piperidin-1-yl]-thiophen-2-yl-methanone::[(2R,4R,5R)-5-[4-(4-fluorophenyl)-1-triazolyl]-4-hydroxy-2-(4-methylphenyl)-1-piperidinyl]-thiophen-2-ylmethanone::SMR001831989::[(2R,4R,5R)-5-[4-(4-fluorophenyl)triazol-1-yl]-4-hydroxy-2-(p-tolyl)piperidino]-(2-thienyl)methanone Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128244 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128244&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 46903185 225154586 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9 259129 CN(Cc1ccccc1)C(=O)OCc1cn(Cc2ccccc2C)nn1 InChI=1S/C20H22N4O2/c1-16-8-6-7-11-18(16)13-24-14-19(21-22-24)15-26-20(25)23(2)12-17-9-4-3-5-10-17/h3-11,14H,12-13,15H2,1-2H3 OJTYSEJIXWWQAF-UHFFFAOYSA-N 128245 SMR002532133::[1-[(2-methylphenyl)methyl]-1,2,3-triazol-4-yl]methyl N-methyl-N-(phenylmethyl)carbamate::[1-[(2-methylphenyl)methyl]triazol-4-yl]methyl N-benzyl-N-methylcarbamate::N-methyl-N-(phenylmethyl)carbamic acid [1-[(2-methylphenyl)methyl]-4-triazolyl]methyl ester::cid_60157353::MLS003875108::N-benzyl-N-methyl-carbamic acid [1-(2-methylbenzyl)triazol-4-yl]methyl ester Transthyretin Homo sapiens >167158 PubChem 10.7270/Q2DN43RH aid1117297 PubChem, PC 12/4/2014 1/12/2015 The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=128245 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6593&target=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=128245&enzyme=Transthyretin&column=ki&startPg=0&Increment=50&submit=Search 60157353 225154587 1 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 8GBR,8G9R,8E7H,8E7D,6SUH,6SUG,6R68,6R67,6R66,4DEW,4ANK,8W48,8IG1,7ERH,7DT5,7DT3,5AYT,4N86,4N85,7EJQ,5E4A,8VE4,8VE3,8VE2,8VE1,8VE0,6U0Q,5U4G,5U4F,5U4E,5U4D,5U4C,5U4B,5U4A,5U49,5U48,5LLL,4D7B,1ZD6,1ZCR,5CNH,5CN3,4PVN,4PVM,4PVL,9H7O,9H7N,9H7M,9H7L,9H7K,9H7J,9H7I,9H7H,9H7G,9H7F,9H7E,9H7D,9H7C,9H7B,9H7A,9FHA,9FF8,8U52,8PM9,8C86,8C85,8ADE,7Z60,7QC5,6GRP,6GR7,5TZL,5L4M,5L4J,5L4I,5L4F,5JIQ,5JIM,5JID,5IHH,5HJG,5EN3,5E23,5BOJ,5AL8,5AL0,5AKV,5AKT,5AKS,4WO0,4WNS,4WNJ,4TQP,4TQI,4TQH,4TQ8,4QXV,4PM1,4MRB,4MAS,4L1T,4L1S,4KY2,4IKL,4IKK,4IKJ,4IKI,4IK7,4IK6,4IIZ,4I85,4HJU,4HJT,4FI8,4FI7,4FI6,4ACT,4AC4,3W3B,3TCT,3P3U,3P3T,3P3S,3P3R,3M1O,3KGU,3IPE,3IPB,3IMW,3IMV,3IMU,3IMT,3IMS,3IMR,3HJ0,3GS7,3GS4,3GS0,3GLZ,3ESP,3ESO,3ESN,3D7P,3D2T,3CN4,3CN3,3CN2,3CN1,3CN0,3CBR,3BSZ,3B56,3A4D,2ROY,2ROX,2QGE,2QGD,2QGC,2QGB,2H4E,2GAB,2G9K,2G5U Transthyretin TTHY_HUMAN P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9