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Compile Data Set for Download or QSAR

Found 77 hits Enz. Inhib. hit(s) with all data for entry = 50014038   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137488
PNG
(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccoc1
Show InChI InChI=1S/C18H18N2O3/c21-18(22)12-6-7-16-15(10-12)19-17(13-8-9-23-11-13)20(16)14-4-2-1-3-5-14/h6-11,14H,1-5H2,(H,21,22)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137475
PNG
(1-Cyclohexyl-2-(1-methyl-1H-pyrrol-2-yl)-1H-benzoi...)
Show SMILES Cn1cccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H21N3O2/c1-21-11-5-8-17(21)18-20-15-12-13(19(23)24)9-10-16(15)22(18)14-6-3-2-4-7-14/h5,8-12,14H,2-4,6-7H2,1H3,(H,23,24)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137467
PNG
(1-Cyclohexyl-2-thiophen-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1cccs1
Show InChI InChI=1S/C18H18N2O2S/c21-18(22)12-8-9-15-14(11-12)19-17(16-7-4-10-23-16)20(15)13-5-2-1-3-6-13/h4,7-11,13H,1-3,5-6H2,(H,21,22)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137504
PNG
(1-Cyclohexyl-2-furan-2-yl-1H-benzoimidazole-5-carb...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccco1
Show InChI InChI=1S/C18H18N2O3/c21-18(22)12-8-9-15-14(11-12)19-17(16-7-4-10-23-16)20(15)13-5-2-1-3-6-13/h4,7-11,13H,1-3,5-6H2,(H,21,22)
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n/an/a 3.70E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137480
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-9-10-17-16(12-13)21-18(15-8-4-5-11-20-15)22(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H,23,24)
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n/an/a 4.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137462
PNG
(1-Cyclohexyl-2-thiazol-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1nccs1
Show InChI InChI=1S/C17H17N3O2S/c21-17(22)11-6-7-14-13(10-11)19-15(16-18-8-9-23-16)20(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,21,22)
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n/an/a 4.60E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137458
PNG
(1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1
Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)
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n/an/a 5.90E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137490
PNG
(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccsc1
Show InChI InChI=1S/C18H18N2O2S/c21-18(22)12-6-7-16-15(10-12)19-17(13-8-9-23-11-13)20(16)14-4-2-1-3-5-14/h6-11,14H,1-5H2,(H,21,22)
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n/an/a 6.33E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137468
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES COc1ccc(CNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC
Show InChI InChI=1S/C28H30N4O3/c1-34-25-14-11-19(16-26(25)35-2)18-30-28(33)20-12-13-24-23(17-20)31-27(22-10-6-7-15-29-22)32(24)21-8-4-3-5-9-21/h6-7,10-17,21H,3-5,8-9,18H2,1-2H3,(H,30,33)
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n/an/a 7.10E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137479
PNG
(1-Cyclohexyl-2-phenyl-1H-benzoimidazole-5-carboxyl...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccc1
Show InChI InChI=1S/C20H20N2O2/c23-20(24)15-11-12-18-17(13-15)21-19(14-7-3-1-4-8-14)22(18)16-9-5-2-6-10-16/h1,3-4,7-8,11-13,16H,2,5-6,9-10H2,(H,23,24)
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n/an/a 8.60E+3n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137481
PNG
(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ncc[nH]1
Show InChI InChI=1S/C17H18N4O2/c22-17(23)11-6-7-14-13(10-11)20-16(15-18-8-9-19-15)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19)(H,22,23)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137464
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC
Show InChI InChI=1S/C29H32N4O3/c1-35-26-14-11-20(18-27(26)36-2)15-17-31-29(34)21-12-13-25-24(19-21)32-28(23-10-6-7-16-30-23)33(25)22-8-4-3-5-9-22/h6-7,10-14,16,18-19,22H,3-5,8-9,15,17H2,1-2H3,(H,31,34)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137487
PNG
(1-Cyclopentyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C18H17N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-3-4-10-19-14)21(16)13-5-1-2-6-13/h3-4,7-11,13H,1-2,5-6H2,(H,22,23)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137493
PNG
(1-Cyclohexyl-2-{4-[(3-dimethylamino-propylcarbamoy...)
Show SMILES CN(C)CCCNC(=O)COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C27H34N4O4/c1-30(2)16-6-15-28-25(32)18-35-22-12-9-19(10-13-22)26-29-23-17-20(27(33)34)11-14-24(23)31(26)21-7-4-3-5-8-21/h9-14,17,21H,3-8,15-16,18H2,1-2H3,(H,28,32)(H,33,34)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137499
PNG
(1-(2-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Show SMILES CC1CCCCC1n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c1-13-6-2-3-8-17(13)23-18-10-9-14(20(24)25)12-16(18)22-19(23)15-7-4-5-11-21-15/h4-5,7,9-13,17H,2-3,6,8H2,1H3,(H,24,25)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137476
PNG
(1-Cyclohexyl-2-{4-[(3-dimethylamino-propylcarbamoy...)
Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccc(OCC(=O)NCCCN(C)C)cc2)cc1OC
Show InChI InChI=1S/C37H47N5O5/c1-41(2)22-8-20-38-35(43)25-47-30-15-12-27(13-16-30)36-40-31-24-28(14-17-32(31)42(36)29-9-6-5-7-10-29)37(44)39-21-19-26-11-18-33(45-3)34(23-26)46-4/h11-18,23-24,29H,5-10,19-22,25H2,1-4H3,(H,38,43)(H,39,44)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137473
PNG
(1-Cyclohexyl-2-pyridin-4-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccncc1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)14-6-7-17-16(12-14)21-18(13-8-10-20-11-9-13)22(17)15-4-2-1-3-5-15/h6-12,15H,1-5H2,(H,23,24)
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n/an/a 1.70E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137484
PNG
(1-Cyclohexyl-2-(2-methyl-propenyl)-1H-benzoimidazo...)
Show SMILES CC(C)=Cc1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C18H22N2O2/c1-12(2)10-17-19-15-11-13(18(21)22)8-9-16(15)20(17)14-6-4-3-5-7-14/h8-11,14H,3-7H2,1-2H3,(H,21,22)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137460
PNG
(1,2-Dicyclohexyl-1H-benzoimidazole-5-carboxylic ac...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)C1CCCCC1
Show InChI InChI=1S/C20H26N2O2/c23-20(24)15-11-12-18-17(13-15)21-19(14-7-3-1-4-8-14)22(18)16-9-5-2-6-10-16/h11-14,16H,1-10H2,(H,23,24)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137492
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C19H20N4O/c20-18(24)13-9-10-17-16(12-13)22-19(15-8-4-5-11-21-15)23(17)14-6-2-1-3-7-14/h4-5,8-12,14H,1-3,6-7H2,(H2,20,24)
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n/an/a 2.70E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137503
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES CNC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C20H22N4O/c1-21-20(25)14-10-11-18-17(13-14)23-19(16-9-5-6-12-22-16)24(18)15-7-3-2-4-8-15/h5-6,9-13,15H,2-4,7-8H2,1H3,(H,21,25)
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n/an/a 2.80E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137472
PNG
(1-Cyclohexyl-2-pyridin-3-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1cccnc1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-8-9-17-16(11-13)21-18(14-5-4-10-20-12-14)22(17)15-6-2-1-3-7-15/h4-5,8-12,15H,1-3,6-7H2,(H,23,24)
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n/an/a 2.80E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137463
PNG
(2-(5-Carboxy-furan-2-yl)-1-cyclohexyl-1H-benzoimid...)
Show SMILES OC(=O)c1ccc(o1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H18N2O5/c22-18(23)11-6-7-14-13(10-11)20-17(15-8-9-16(26-15)19(24)25)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,22,23)(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137459
PNG
(2-(5-Bromo-furan-2-yl)-1-cyclohexyl-1H-benzoimidaz...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(Br)o1
Show InChI InChI=1S/C18H17BrN2O3/c19-16-9-8-15(24-16)17-20-13-10-11(18(22)23)6-7-14(13)21(17)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137483
PNG
(1-Cyclohexyl-2-(3-phenyl-1H-pyrazol-4-yl)-1H-benzo...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1c[nH]nc1-c1ccccc1
Show InChI InChI=1S/C23H22N4O2/c28-23(29)16-11-12-20-19(13-16)25-22(27(20)17-9-5-2-6-10-17)18-14-24-26-21(18)15-7-3-1-4-8-15/h1,3-4,7-8,11-14,17H,2,5-6,9-10H2,(H,24,26)(H,28,29)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137470
PNG
(1-Cyclohexyl-2-(5-ethyl-furan-2-yl)-1H-benzoimidaz...)
Show SMILES CCc1ccc(o1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H22N2O3/c1-2-15-9-11-18(25-15)19-21-16-12-13(20(23)24)8-10-17(16)22(19)14-6-4-3-5-7-14/h8-12,14H,2-7H2,1H3,(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137465
PNG
(1-Cyclohexyl-2-(5-ethyl-thiophen-2-yl)-1H-benzoimi...)
Show SMILES CCc1ccc(s1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H22N2O2S/c1-2-15-9-11-18(25-15)19-21-16-12-13(20(23)24)8-10-17(16)22(19)14-6-4-3-5-7-14/h8-12,14H,2-7H2,1H3,(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137477
PNG
(1-Cyclohexyl-2-(5-methyl-3H-imidazol-4-yl)-1H-benz...)
Show SMILES Cc1[nH]cnc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C18H20N4O2/c1-11-16(20-10-19-11)17-21-14-9-12(18(23)24)7-8-15(14)22(17)13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H,19,20)(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137482
PNG
(1-Cyclohexyl-2-(4,5-dimethyl-furan-2-yl)-1H-benzoi...)
Show SMILES Cc1cc(oc1C)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H22N2O3/c1-12-10-18(25-13(12)2)19-21-16-11-14(20(23)24)8-9-17(16)22(19)15-6-4-3-5-7-15/h8-11,15H,3-7H2,1-2H3,(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137498
PNG
(1-Cyclohexyl-2-(5-hydroxymethyl-furan-2-yl)-1H-ben...)
Show SMILES OCc1ccc(o1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H20N2O4/c22-11-14-7-9-17(25-14)18-20-15-10-12(19(23)24)6-8-16(15)21(18)13-4-2-1-3-5-13/h6-10,13,22H,1-5,11H2,(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137471
PNG
(2-(5-Carboxy-thiophen-2-yl)-1-cyclohexyl-1H-benzoi...)
Show SMILES OC(=O)c1ccc(s1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H18N2O4S/c22-18(23)11-6-7-14-13(10-11)20-17(15-8-9-16(26-15)19(24)25)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,22,23)(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137495
PNG
(1-Cyclohexyl-2-(6-methyl-pyridin-2-yl)-1H-benzoimi...)
Show SMILES Cc1cccc(n1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H21N3O2/c1-13-6-5-9-16(21-13)19-22-17-12-14(20(24)25)10-11-18(17)23(19)15-7-3-2-4-8-15/h5-6,9-12,15H,2-4,7-8H2,1H3,(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137496
PNG
(1-Cyclohexyl-2-quinolin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc2ccccc2n1
Show InChI InChI=1S/C23H21N3O2/c27-23(28)16-11-13-21-20(14-16)25-22(26(21)17-7-2-1-3-8-17)19-12-10-15-6-4-5-9-18(15)24-19/h4-6,9-14,17H,1-3,7-8H2,(H,27,28)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137501
PNG
(1-Cyclohexyl-2-(5-methyl-thiophen-2-yl)-1H-benzoim...)
Show SMILES Cc1ccc(s1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C19H20N2O2S/c1-12-7-10-17(24-12)18-20-15-11-13(19(22)23)8-9-16(15)21(18)14-5-3-2-4-6-14/h7-11,14H,2-6H2,1H3,(H,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137500
PNG
(1-Cyclohexyl-2-(3-methyl-1H-indol-2-yl)-1H-benzoim...)
Show SMILES Cc1c([nH]c2ccccc12)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C23H23N3O2/c1-14-17-9-5-6-10-18(17)24-21(14)22-25-19-13-15(23(27)28)11-12-20(19)26(22)16-7-3-2-4-8-16/h5-6,9-13,16,24H,2-4,7-8H2,1H3,(H,27,28)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137485
PNG
(2-[5-(4-Chloro-phenyl)-furan-2-yl]-1-cyclohexyl-1H...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H21ClN2O3/c25-17-9-6-15(7-10-17)21-12-13-22(30-21)23-26-19-14-16(24(28)29)8-11-20(19)27(23)18-4-2-1-3-5-18/h6-14,18H,1-5H2,(H,28,29)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137469
PNG
(2-Benzoyl-1-cyclohexyl-1H-benzoimidazole-5-carboxy...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)C(=O)c1ccccc1
Show InChI InChI=1S/C21H20N2O3/c24-19(14-7-3-1-4-8-14)20-22-17-13-15(21(25)26)11-12-18(17)23(20)16-9-5-2-6-10-16/h1,3-4,7-8,11-13,16H,2,5-6,9-10H2,(H,25,26)
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n/an/a 4.40E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137502
PNG
(1-Cycloheptyl-2-pyridin-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c24-20(25)14-10-11-18-17(13-14)22-19(16-9-5-6-12-21-16)23(18)15-7-3-1-2-4-8-15/h5-6,9-13,15H,1-4,7-8H2,(H,24,25)
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n/an/a 4.90E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137491
PNG
(1-(4-Methyl-cyclohexyl)-2-pyridin-2-yl-1H-benzoimi...)
Show SMILES CC1CCC(CC1)n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C20H21N3O2/c1-13-5-8-15(9-6-13)23-18-10-7-14(20(24)25)12-17(18)22-19(23)16-4-2-3-11-21-16/h2-4,7,10-13,15H,5-6,8-9H2,1H3,(H,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137486
PNG
(2-Benzofuran-2-yl-1-cyclohexyl-1H-benzoimidazole-5...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1cc2ccccc2o1
Show InChI InChI=1S/C22H20N2O3/c25-22(26)15-10-11-18-17(12-15)23-21(24(18)16-7-2-1-3-8-16)20-13-14-6-4-5-9-19(14)27-20/h4-6,9-13,16H,1-3,7-8H2,(H,25,26)
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n/an/a 5.80E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137478
PNG
(1-Cyclohexyl-1H-benzoimidazole-2,5-dicarboxylic ac...)
Show SMILES CCOC(=O)c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C17H20N2O4/c1-2-23-17(22)15-18-13-10-11(16(20)21)8-9-14(13)19(15)12-6-4-3-5-7-12/h8-10,12H,2-7H2,1H3,(H,20,21)
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n/an/a 6.20E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137461
PNG
(1-Cyclobutyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C17H15N3O2/c21-17(22)11-7-8-15-14(10-11)19-16(13-6-1-2-9-18-13)20(15)12-4-3-5-12/h1-2,6-10,12H,3-5H2,(H,21,22)
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n/an/a 7.60E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137494
PNG
(1-Cyclohexyl-2-(2,4,6-trimethyl-phenyl)-1H-benzoim...)
Show SMILES Cc1cc(C)c(-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(C)c1
Show InChI InChI=1S/C23H26N2O2/c1-14-11-15(2)21(16(3)12-14)22-24-19-13-17(23(26)27)9-10-20(19)25(22)18-7-5-4-6-8-18/h9-13,18H,4-8H2,1-3H3,(H,26,27)
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n/an/a 1.20E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137505
PNG
(1-(1-Ethyl-propyl)-2-pyridin-2-yl-1H-benzoimidazol...)
Show SMILES CCC(CC)n1c(nc2cc(ccc12)C(O)=O)-c1ccccn1
Show InChI InChI=1S/C18H19N3O2/c1-3-13(4-2)21-16-9-8-12(18(22)23)11-15(16)20-17(21)14-7-5-6-10-19-14/h5-11,13H,3-4H2,1-2H3,(H,22,23)
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n/an/a 1.39E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50137497
PNG
(1-Cyclohexyl-1H-benzoimidazole-5-carboxylic acid |...)
Show SMILES OC(=O)c1ccc2n(cnc2c1)C1CCCCC1
Show InChI InChI=1S/C14H16N2O2/c17-14(18)10-6-7-13-12(8-10)15-9-16(13)11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H,17,18)
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n/an/a 1.86E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137488
PNG
(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccoc1
Show InChI InChI=1S/C18H18N2O3/c21-18(22)12-6-7-16-15(10-12)19-17(13-8-9-23-11-13)20(16)14-4-2-1-3-5-14/h6-11,14H,1-5H2,(H,21,22)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137472
PNG
(1-Cyclohexyl-2-pyridin-3-yl-1H-benzoimidazole-5-ca...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1cccnc1
Show InChI InChI=1S/C19H19N3O2/c23-19(24)13-8-9-17-16(11-13)21-18(14-5-4-10-20-12-14)22(17)15-6-2-1-3-7-15/h4-5,8-12,15H,1-3,6-7H2,(H,23,24)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137467
PNG
(1-Cyclohexyl-2-thiophen-2-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1cccs1
Show InChI InChI=1S/C18H18N2O2S/c21-18(22)12-8-9-15-14(11-12)19-17(16-7-4-10-23-16)20(15)13-5-2-1-3-6-13/h4,7-11,13H,1-3,5-6H2,(H,21,22)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137481
PNG
(1-Cyclohexyl-2-(1H-imidazol-2-yl)-1H-benzoimidazol...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ncc[nH]1
Show InChI InChI=1S/C17H18N4O2/c22-17(23)11-6-7-14-13(10-11)20-16(15-18-8-9-19-15)21(14)12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,18,19)(H,22,23)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137490
PNG
(1-Cyclohexyl-2-thiophen-3-yl-1H-benzoimidazole-5-c...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccsc1
Show InChI InChI=1S/C18H18N2O2S/c21-18(22)12-6-7-16-15(10-12)19-17(13-8-9-23-11-13)20(16)14-4-2-1-3-5-14/h6-11,14H,1-5H2,(H,21,22)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair
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