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Compile Data Set for Download or QSAR

Found 70 hits Enz. Inhib. hit(s) with all data for entry = 50034898   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290221
PNG
(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-
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0.0200n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50063279
PNG
(CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...)
Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1
Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-
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0.140n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290206
PNG
(CHEMBL78800 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C23H30ClN3OS/c24-20-4-1-2-5-21(20)27-15-13-26(14-16-27)12-11-18-7-9-19(10-8-18)25-23(28)22-6-3-17-29-22/h1-6,17-19H,7-16H2,(H,25,28)/t18-,19-
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0.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50054067
PNG
((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1
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0.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50054067
PNG
((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1
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0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290221
PNG
(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-
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0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290225
PNG
(CHEMBL78950 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3O2S/c1-29-22-6-3-2-5-21(22)27-16-14-26(15-17-27)13-12-19-8-10-20(11-9-19)25-24(28)23-7-4-18-30-23/h2-7,18-20H,8-17H2,1H3,(H,25,28)/t19-,20-
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0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50063291
PNG
(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1
Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-
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0.800n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290206
PNG
(CHEMBL78800 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C23H30ClN3OS/c24-20-4-1-2-5-21(20)27-15-13-26(14-16-27)12-11-18-7-9-19(10-8-18)25-23(28)22-6-3-17-29-22/h1-6,17-19H,7-16H2,(H,25,28)/t18-,19-
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1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290209
PNG
(CHEMBL310577 | Thiophene-2-carboxylic acid (4-{2-[...)
Show SMILES COc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3O2S/c1-29-22-5-2-4-21(18-22)27-15-13-26(14-16-27)12-11-19-7-9-20(10-8-19)25-24(28)23-6-3-17-30-23/h2-6,17-20H,7-16H2,1H3,(H,25,28)/t19-,20-
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1.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290214
PNG
(CHEMBL312430 | Furan-2-carboxylic acid (4-{2-[4-(2...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccco3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3O2/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-
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1.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290225
PNG
(CHEMBL78950 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES COc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3O2S/c1-29-22-6-3-2-5-21(22)27-16-14-26(15-17-27)13-12-19-8-10-20(11-9-19)25-24(28)23-7-4-18-30-23/h2-7,18-20H,8-17H2,1H3,(H,25,28)/t19-,20-
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1.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290218
PNG
(CHEMBL78617 | Cyclopentanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCC3)CC2)c1Cl
Show InChI InChI=1S/C24H35Cl2N3O/c25-21-6-3-7-22(23(21)26)29-16-14-28(15-17-29)13-12-18-8-10-20(11-9-18)27-24(30)19-4-1-2-5-19/h3,6-7,18-20H,1-2,4-5,8-17H2,(H,27,30)/t18-,20-
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1.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290221
PNG
(CHEMBL80919 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccs3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3OS/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-
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1.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50063279
PNG
(CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...)
Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)C1CCCCC1
Show InChI InChI=1S/C25H39N3O/c29-25(22-7-3-1-4-8-22)26-23-13-11-21(12-14-23)15-16-27-17-19-28(20-18-27)24-9-5-2-6-10-24/h2,5-6,9-10,21-23H,1,3-4,7-8,11-20H2,(H,26,29)/t21-,23-
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2n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290210
PNG
(CHEMBL78368 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C23H30ClN3OS/c24-19-3-1-4-21(17-19)27-14-12-26(13-15-27)11-10-18-6-8-20(9-7-18)25-23(28)22-5-2-16-29-22/h1-5,16-18,20H,6-15H2,(H,25,28)/t18-,20-
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2n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290213
PNG
(CHEMBL80875 | Thiophene-2-carboxylic acid {4-[2-(4...)
Show SMILES Cc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-4-2-5-22(18-19)27-15-13-26(14-16-27)12-11-20-7-9-21(10-8-20)25-24(28)23-6-3-17-29-23/h2-6,17-18,20-21H,7-16H2,1H3,(H,25,28)/t20-,21-
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2.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290217
PNG
(CHEMBL78916 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-et...)
Show SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1
Show InChI InChI=1S/C20H31N3O/c1-17(24)21-19-9-7-18(8-10-19)11-12-22-13-15-23(16-14-22)20-5-3-2-4-6-20/h2-6,18-19H,7-16H2,1H3,(H,21,24)/t18-,19-
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2.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290214
PNG
(CHEMBL312430 | Furan-2-carboxylic acid (4-{2-[4-(2...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccco3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3O2/c24-19-3-1-4-20(22(19)25)28-14-12-27(13-15-28)11-10-17-6-8-18(9-7-17)26-23(29)21-5-2-16-30-21/h1-5,16-18H,6-15H2,(H,26,29)/t17-,18-
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3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290232
PNG
(CHEMBL309501 | Thiophene-2-carboxylic acid {4-[2-(...)
Show SMILES Cc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-5-2-3-6-22(19)27-16-14-26(15-17-27)13-12-20-8-10-21(11-9-20)25-24(28)23-7-4-18-29-23/h2-7,18,20-21H,8-17H2,1H3,(H,25,28)/t20-,21-
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3.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50063291
PNG
(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1)c1cccs1
Show InChI InChI=1S/C23H31N3OS/c27-23(22-7-4-18-28-22)24-20-10-8-19(9-11-20)12-13-25-14-16-26(17-15-25)21-5-2-1-3-6-21/h1-7,18-20H,8-17H2,(H,24,27)/t19-,20-
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3.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290218
PNG
(CHEMBL78617 | Cyclopentanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCC3)CC2)c1Cl
Show InChI InChI=1S/C24H35Cl2N3O/c25-21-6-3-7-22(23(21)26)29-16-14-28(15-17-29)13-12-18-8-10-20(11-9-18)27-24(30)19-4-1-2-5-19/h3,6-7,18-20H,1-2,4-5,8-17H2,(H,27,30)/t18-,20-
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4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290212
PNG
(CHEMBL80315 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1
Show InChI InChI=1S/C24H31Cl2N3OS/c1-27(24(30)22-6-3-17-31-22)19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)21-5-2-4-20(25)23(21)26/h2-6,17-19H,7-16H2,1H3/t18-,19-
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4.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290211
PNG
(CHEMBL311575 | Thiophene-2-carboxylic acid {4-[2-(...)
Show SMILES Cc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-4-10-22(11-5-19)27-16-14-26(15-17-27)13-12-20-6-8-21(9-7-20)25-24(28)23-3-2-18-29-23/h2-5,10-11,18,20-21H,6-9,12-17H2,1H3,(H,25,28)/t20-,21-
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4.30n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290229
PNG
(CHEMBL78406 | PD-137557 | Thiophene-2-carboxylic a...)
Show SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1cccs1
Show InChI InChI=1S/C22H30N4OS/c27-22(20-4-3-17-28-20)24-19-8-6-18(7-9-19)10-12-25-13-15-26(16-14-25)21-5-1-2-11-23-21/h1-5,11,17-19H,6-10,12-16H2,(H,24,27)/t18-,19-
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4.30n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290223
PNG
(CHEMBL309979 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCC3)CC2)c1Cl
Show InChI InChI=1S/C25H37Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h4,7-8,19-21H,1-3,5-6,9-18H2,(H,28,31)/t19-,21-
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4.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290220
PNG
(CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl
Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-
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4.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290220
PNG
(CHEMBL430439 | N-(4-{2-[4-(2,3-Dichloro-phenyl)-pi...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)CC2)c1Cl
Show InChI InChI=1S/C25H31Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h1-8,19,21H,9-18H2,(H,28,31)/t19-,21-
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4.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290230
PNG
(CHEMBL309727 | Thiophene-3-carboxylic acid (4-{2-[...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccsc3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3OS/c24-20-2-1-3-21(22(20)25)28-13-11-27(12-14-28)10-8-17-4-6-19(7-5-17)26-23(29)18-9-15-30-16-18/h1-3,9,15-17,19H,4-8,10-14H2,(H,26,29)/t17-,19-
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4.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290224
PNG
(CHEMBL78195 | Cycloheptanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCCC3)CC2)c1Cl
Show InChI InChI=1S/C26H39Cl2N3O/c27-23-8-5-9-24(25(23)28)31-18-16-30(17-19-31)15-14-20-10-12-22(13-11-20)29-26(32)21-6-3-1-2-4-7-21/h5,8-9,20-22H,1-4,6-7,10-19H2,(H,29,32)/t20-,22-
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4.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290207
PNG
(CHEMBL310204 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C25H38ClN3O/c26-23-8-4-5-9-24(23)29-18-16-28(17-19-29)15-14-20-10-12-22(13-11-20)27-25(30)21-6-2-1-3-7-21/h4-5,8-9,20-22H,1-3,6-7,10-19H2,(H,27,30)/t20-,22-
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5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290232
PNG
(CHEMBL309501 | Thiophene-2-carboxylic acid {4-[2-(...)
Show SMILES Cc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-5-2-3-6-22(19)27-16-14-26(15-17-27)13-12-20-8-10-21(11-9-20)25-24(28)23-7-4-18-29-23/h2-7,18,20-21H,8-17H2,1H3,(H,25,28)/t20-,21-
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5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290230
PNG
(CHEMBL309727 | Thiophene-3-carboxylic acid (4-{2-[...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3ccsc3)CC2)c1Cl
Show InChI InChI=1S/C23H29Cl2N3OS/c24-20-2-1-3-21(22(20)25)28-13-11-27(12-14-28)10-8-17-4-6-19(7-5-17)26-23(29)18-9-15-30-16-18/h1-3,9,15-17,19H,4-8,10-14H2,(H,26,29)/t17-,19-
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5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290233
PNG
(CHEMBL80615 | Cyclohexanecarboxylic acid (4-{2-[4-...)
Show SMILES Cc1ccc(cc1C)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C27H43N3O/c1-21-8-13-26(20-22(21)2)30-18-16-29(17-19-30)15-14-23-9-11-25(12-10-23)28-27(31)24-6-4-3-5-7-24/h8,13,20,23-25H,3-7,9-12,14-19H2,1-2H3,(H,28,31)/t23-,25-
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5.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290233
PNG
(CHEMBL80615 | Cyclohexanecarboxylic acid (4-{2-[4-...)
Show SMILES Cc1ccc(cc1C)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C27H43N3O/c1-21-8-13-26(20-22(21)2)30-18-16-29(17-19-30)15-14-23-9-11-25(12-10-23)28-27(31)24-6-4-3-5-7-24/h8,13,20,23-25H,3-7,9-12,14-19H2,1-2H3,(H,28,31)/t23-,25-
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5.60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290219
PNG
(CHEMBL310401 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C25H38ClN3O/c26-22-7-4-8-24(19-22)29-17-15-28(16-18-29)14-13-20-9-11-23(12-10-20)27-25(30)21-5-2-1-3-6-21/h4,7-8,19-21,23H,1-3,5-6,9-18H2,(H,27,30)/t20-,23-
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6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290213
PNG
(CHEMBL80875 | Thiophene-2-carboxylic acid {4-[2-(4...)
Show SMILES Cc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-4-2-5-22(18-19)27-15-13-26(14-16-27)12-11-20-7-9-21(10-8-20)25-24(28)23-6-3-17-29-23/h2-6,17-18,20-21H,7-16H2,1H3,(H,25,28)/t20-,21-
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6.30n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290210
PNG
(CHEMBL78368 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C23H30ClN3OS/c24-19-3-1-4-21(17-19)27-14-12-26(13-15-27)11-10-18-6-8-20(9-7-18)25-23(28)22-5-2-16-29-22/h1-5,16-18,20H,6-15H2,(H,25,28)/t18-,20-
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6.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290223
PNG
(CHEMBL309979 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCC3)CC2)c1Cl
Show InChI InChI=1S/C25H37Cl2N3O/c26-22-7-4-8-23(24(22)27)30-17-15-29(16-18-30)14-13-19-9-11-21(12-10-19)28-25(31)20-5-2-1-3-6-20/h4,7-8,19-21H,1-3,5-6,9-18H2,(H,28,31)/t19-,21-
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7.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290208
PNG
(CHEMBL309459 | Thiophene-2-carboxylic acid (4-{2-[...)
Show SMILES Clc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C23H30ClN3OS/c24-19-5-9-21(10-6-19)27-15-13-26(14-16-27)12-11-18-3-7-20(8-4-18)25-23(28)22-2-1-17-29-22/h1-2,5-6,9-10,17-18,20H,3-4,7-8,11-16H2,(H,25,28)/t18-,20-
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8n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290217
PNG
(CHEMBL78916 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-et...)
Show SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1
Show InChI InChI=1S/C20H31N3O/c1-17(24)21-19-9-7-18(8-10-19)11-12-22-13-15-23(16-14-22)20-5-3-2-4-6-20/h2-6,18-19H,7-16H2,1H3,(H,21,24)/t18-,19-
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290216
PNG
(5-Methyl-thiophene-2-carboxylic acid (4-{2-[4-(2,3...)
Show SMILES Cc1ccc(s1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1
Show InChI InChI=1S/C24H31Cl2N3OS/c1-17-5-10-22(31-17)24(30)27-19-8-6-18(7-9-19)11-12-28-13-15-29(16-14-28)21-4-2-3-20(25)23(21)26/h2-5,10,18-19H,6-9,11-16H2,1H3,(H,27,30)/t18-,19-
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290227
PNG
(3-Methyl-thiophene-2-carboxylic acid (4-{2-[4-(2,3...)
Show SMILES Cc1ccsc1C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1
Show InChI InChI=1S/C24H31Cl2N3OS/c1-17-10-16-31-23(17)24(30)27-19-7-5-18(6-8-19)9-11-28-12-14-29(15-13-28)21-4-2-3-20(25)22(21)26/h2-4,10,16,18-19H,5-9,11-15H2,1H3,(H,27,30)/t18-,19-
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11n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290224
PNG
(CHEMBL78195 | Cycloheptanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCCC3)CC2)c1Cl
Show InChI InChI=1S/C26H39Cl2N3O/c27-23-8-5-9-24(25(23)28)31-18-16-30(17-19-31)15-14-20-10-12-22(13-11-20)29-26(32)21-6-3-1-2-4-7-21/h5,8-9,20-22H,1-4,6-7,10-19H2,(H,29,32)/t20-,22-
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12n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290209
PNG
(CHEMBL310577 | Thiophene-2-carboxylic acid (4-{2-[...)
Show SMILES COc1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3O2S/c1-29-22-5-2-4-21(18-22)27-15-13-26(14-16-27)12-11-19-7-9-20(10-8-19)25-24(28)23-6-3-17-30-23/h2-6,17-20H,7-16H2,1H3,(H,25,28)/t19-,20-
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12n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290215
PNG
(CHEMBL312803 | Thiophene-2-carboxylic acid (4-{2-[...)
Show SMILES COc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3O2S/c1-29-22-10-8-21(9-11-22)27-16-14-26(15-17-27)13-12-19-4-6-20(7-5-19)25-24(28)23-3-2-18-30-23/h2-3,8-11,18-20H,4-7,12-17H2,1H3,(H,25,28)/t19-,20-
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12n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50290231
PNG
(CHEMBL310680 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C25H38ClN3O/c26-22-8-12-24(13-9-22)29-18-16-28(17-19-29)15-14-20-6-10-23(11-7-20)27-25(30)21-4-2-1-3-5-21/h8-9,12-13,20-21,23H,1-7,10-11,14-19H2,(H,27,30)/t20-,23-
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290207
PNG
(CHEMBL310204 | Cyclohexanecarboxylic acid (4-{2-[4...)
Show SMILES Clc1ccccc1N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)C2CCCCC2)CC1
Show InChI InChI=1S/C25H38ClN3O/c26-23-8-4-5-9-24(23)29-18-16-28(17-19-29)15-14-20-10-12-22(13-11-20)27-25(30)21-6-2-1-3-7-21/h4-5,8-9,20-22H,1-3,6-7,10-19H2,(H,27,30)/t20-,22-
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290211
PNG
(CHEMBL311575 | Thiophene-2-carboxylic acid {4-[2-(...)
Show SMILES Cc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)NC(=O)c2cccs2)CC1
Show InChI InChI=1S/C24H33N3OS/c1-19-4-10-22(11-5-19)27-16-14-26(15-17-27)13-12-20-6-8-21(9-7-20)25-24(28)23-3-2-18-29-23/h2-5,10-11,18,20-21H,6-9,12-17H2,1H3,(H,25,28)/t20-,21-
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17n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50290212
PNG
(CHEMBL80315 | Thiophene-2-carboxylic acid (4-{2-[4...)
Show SMILES CN([C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1)C(=O)c1cccs1
Show InChI InChI=1S/C24H31Cl2N3OS/c1-27(24(30)22-6-3-17-31-22)19-9-7-18(8-10-19)11-12-28-13-15-29(16-14-28)21-5-2-4-20(25)23(21)26/h2-6,17-19H,7-16H2,1H3/t18-,19-
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17n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.


Bioorg Med Chem Lett 7: 2403-2408 (1997)


Article DOI: 10.1016/S0960-894X(97)00443-5
BindingDB Entry DOI: 10.7270/Q27W6CQ0
More data for this
Ligand-Target Pair
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