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Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50041032   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50154716
PNG
((-)-1-Methyl-4-(8-methylsulfanyl-10,11-dihydro-dib...)
Show SMILES CSc1ccc2Sc3ccccc3C[C@H](N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3/t18-/m0/s1
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1n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403780
PNG
(CHEMBL12846)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCC(CC1)c1ccccc1)c23
Show InChI InChI=1S/C26H32N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12,21H,4-5,7,11,13-19H2,(H,27,29)
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2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403759
PNG
(CHEMBL428494)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccn1)c23
Show InChI InChI=1S/C24H30N4O/c29-23-24(12-6-8-19-7-5-9-20(26-23)22(19)24)11-2-4-14-27-15-17-28(18-16-27)21-10-1-3-13-25-21/h1,3,5,7,9-10,13H,2,4,6,8,11-12,14-18H2,(H,26,29)
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2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50130279
PNG
((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(C)c2)CC1
Show InChI InChI=1S/C19H30N2O2S/c1-16-8-12-20(13-9-16)14-10-18-6-4-11-21(18)24(22,23)19-7-3-5-17(2)15-19/h3,5,7,15-16,18H,4,6,8-14H2,1-2H3/t18-/m1/s1
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3.20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403770
PNG
(CHEMBL12427)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C25H31N3O/c29-24-25(14-7-9-20-8-6-12-22(26-24)23(20)25)13-4-5-15-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h1-3,6,8,10-12H,4-5,7,9,13-19H2,(H,26,29)
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3.20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403768
PNG
(CHEMBL273246)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccc1C#N)c23
Show InChI InChI=1S/C26H30N4O/c27-19-21-7-1-2-11-23(21)30-17-15-29(16-18-30)14-4-3-12-26-13-6-9-20-8-5-10-22(24(20)26)28-25(26)31/h1-2,5,7-8,10-11H,3-4,6,9,12-18H2,(H,28,31)
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4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403777
PNG
(CHEMBL12702)
Show SMILES COc1ccccc1N1CCN(CCCCC23CCCc4cccc(NC2=O)c34)CC1
Show InChI InChI=1S/C26H33N3O2/c1-31-23-12-3-2-11-22(23)29-18-16-28(17-19-29)15-5-4-13-26-14-7-9-20-8-6-10-21(24(20)26)27-25(26)30/h2-3,6,8,10-12H,4-5,7,9,13-19H2,1H3,(H,27,30)
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5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50130272
PNG
(2a-[3-(4-Phenyl-piperazin-1-yl)-propyl]-2a,3,4,5-t...)
Show SMILES O=C1Nc2cccc3CCCC1(CCCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C24H29N3O/c28-23-24(12-5-8-19-7-4-11-21(25-23)22(19)24)13-6-14-26-15-17-27(18-16-26)20-9-2-1-3-10-20/h1-4,7,9-11H,5-6,8,12-18H2,(H,25,28)
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5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM30704
PNG
((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13
Show InChI InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1
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6.30n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50024204
PNG
(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Show SMILES CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1
Show InChI InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1
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7.90n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50130269
PNG
((6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-i...)
Show SMILES CCN(CC)C(=O)[C@H]1CN(C)[C@@H]2Cc3c(Br)[nH]c4cccc(C2=C1)c34
Show InChI InChI=1S/C20H24BrN3O/c1-4-24(5-2)20(25)12-9-14-13-7-6-8-16-18(13)15(19(21)22-16)10-17(14)23(3)11-12/h6-9,12,17,22H,4-5,10-11H2,1-3H3/t12-,17-/m1/s1
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10n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50031942
PNG
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Show SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34
Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1
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13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001775
PNG
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Show SMILES Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3
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16n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403758
PNG
(CHEMBL274595)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cc(Br)c(Br)s1
Show InChI InChI=1S/C15H24Br2N2O2S2/c1-11-4-7-19(8-5-11)9-6-12(2)18(3)23(20,21)14-10-13(16)15(17)22-14/h10-12H,4-9H2,1-3H3/t12-/m1/s1
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16n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM21397
PNG
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
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20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403771
PNG
(CHEMBL12771)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1ccc(Br)c(Br)c1
Show InChI InChI=1S/C17H26Br2N2O2S/c1-13-6-9-21(10-7-13)11-8-14(2)20(3)24(22,23)15-4-5-16(18)17(19)12-15/h4-5,12-14H,6-11H2,1-3H3/t14-/m1/s1
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20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403775
PNG
(CHEMBL275996)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H26Cl2N2O2S/c1-13-6-9-21(10-7-13)11-8-14(2)20(3)24(22,23)15-4-5-16(18)17(19)12-15/h4-5,12-14H,6-11H2,1-3H3/t14-/m1/s1
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32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50098550
PNG
(3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin...)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1
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32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403760
PNG
(CHEMBL12777)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-11-14-23(15-12-17)16-13-18(2)22(3)26(24,25)21-10-6-8-19-7-4-5-9-20(19)21/h4-10,17-18H,11-16H2,1-3H3/t18-/m1/s1
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32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50017721
PNG
(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Show SMILES CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
Show InChI InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
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50n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50130282
PNG
(CHEMBL13049 | Naphthalene-1-sulfonic acid methyl-[...)
Show SMILES CC(CCN1CCCC(C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-8-7-14-23(16-17)15-13-18(2)22(3)26(24,25)21-12-6-10-19-9-4-5-11-20(19)21/h4-6,9-12,17-18H,7-8,13-16H2,1-3H3
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63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50008735
PNG
((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34
Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1
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63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403764
PNG
(CHEMBL276206)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C26H29N3O2/c1-31-24-13-3-2-11-22(24)28-18-16-27(17-19-28)14-4-5-15-29-23-12-7-9-20-8-6-10-21(25(20)23)26(29)30/h2-3,6-13H,4-5,14-19H2,1H3
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63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM31005
PNG
(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyraz...)
Show SMILES Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Show InChI InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H
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63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50240359
PNG
(1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...)
Show SMILES O=C1N(CCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H29N3O/c30-26-23-13-7-9-21-10-8-14-24(25(21)23)29(26)16-6-2-5-15-27-17-19-28(20-18-27)22-11-3-1-4-12-22/h1,3-4,7-14H,2,5-6,15-20H2
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79n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403772
PNG
(CHEMBL268921)
Show SMILES O=C1Nc2cccc3CCCC1(CCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C23H27N3O/c27-22-23(11-5-7-18-6-4-10-20(24-22)21(18)23)12-13-25-14-16-26(17-15-25)19-8-2-1-3-9-19/h1-4,6,8-10H,5,7,11-17H2,(H,24,27)
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100n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor using [3H]5-CT as radioligand


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403774
PNG
(CHEMBL273982)
Show SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C27H31N3O2/c1-32-25-14-4-3-12-23(25)29-19-17-28(18-20-29)15-5-2-6-16-30-24-13-8-10-21-9-7-11-22(26(21)24)27(30)31/h3-4,7-14H,2,5-6,15-20H2,1H3
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100n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403765
PNG
(CHEMBL12389)
Show SMILES C[C@H](CCN1CCC[C@@H](C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-8-7-14-23(16-17)15-13-18(2)22(3)26(24,25)21-12-6-10-19-9-4-5-11-20(19)21/h4-6,9-12,17-18H,7-8,13-16H2,1-3H3/t17-,18-/m1/s1
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126n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403763
PNG
(CHEMBL12908)
Show SMILES COc1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C27H33N3O3S/c1-33-25-14-5-4-12-23(25)29-20-18-28(19-21-29)16-6-2-3-7-17-30-24-13-8-10-22-11-9-15-26(27(22)24)34(30,31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3
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200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403762
PNG
(CHEMBL273452)
Show SMILES CC(C)C1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C23H30N2O/c1-17(2)18-11-15-24(16-12-18)13-3-4-14-25-21-10-6-8-19-7-5-9-20(22(19)21)23(25)26/h5-10,17-18H,3-4,11-16H2,1-2H3
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200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403778
PNG
(CHEMBL12933)
Show SMILES O=S1(=O)N(CCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C25H29N3O2S/c29-31(30)24-14-8-10-21-9-7-13-23(25(21)24)28(31)16-6-2-5-15-26-17-19-27(20-18-26)22-11-3-1-4-12-22/h1,3-4,7-14H,2,5-6,15-20H2
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200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403779
PNG
(CHEMBL13032)
Show SMILES COc1ccccc1N1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C25H29N3O3S/c1-31-23-12-3-2-10-21(23)27-18-16-26(17-19-27)14-4-5-15-28-22-11-6-8-20-9-7-13-24(25(20)22)32(28,29)30/h2-3,6-13H,4-5,14-19H2,1H3
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200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403784
PNG
(CHEMBL430280)
Show SMILES COc1ccccc1N1CCN(CCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C26H31N3O3S/c1-32-24-13-4-3-11-22(24)28-19-17-27(18-20-28)15-5-2-6-16-29-23-12-7-9-21-10-8-14-25(26(21)23)33(29,30)31/h3-4,7-14H,2,5-6,15-20H2,1H3
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251n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403766
PNG
(CHEMBL12654)
Show SMILES C[C@H](CCN1CCC[C@H](C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-8-7-14-23(16-17)15-13-18(2)22(3)26(24,25)21-12-6-10-19-9-4-5-11-20(19)21/h4-6,9-12,17-18H,7-8,13-16H2,1-3H3/t17-,18+/m0/s1
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631n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403781
PNG
(CHEMBL275495)
Show SMILES CC1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C21H26N2O/c1-16-10-14-22(15-11-16)12-2-3-13-23-19-9-5-7-17-6-4-8-18(20(17)19)21(23)24/h4-9,16H,2-3,10-15H2,1H3
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<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403773
PNG
(CHEMBL267543)
Show SMILES C[C@@H](CCN1CCC[C@@H](C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-8-7-14-23(16-17)15-13-18(2)22(3)26(24,25)21-12-6-10-19-9-4-5-11-20(19)21/h4-6,9-12,17-18H,7-8,13-16H2,1-3H3/t17-,18+/m1/s1
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1.59E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403761
PNG
(CHEMBL12656)
Show SMILES CC1CCN(CCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C21H28N2O2S/c1-17-11-15-22(16-12-17)13-3-2-4-14-23-19-9-5-7-18-8-6-10-20(21(18)19)26(23,24)25/h5-10,17H,2-4,11-16H2,1H3
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403769
PNG
(CHEMBL276255)
Show SMILES C[C@@H](CCN1CCC[C@H](C)C1)N(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H30N2O2S/c1-17-8-7-14-23(16-17)15-13-18(2)22(3)26(24,25)21-12-6-10-19-9-4-5-11-20(19)21/h4-6,9-12,17-18H,7-8,13-16H2,1-3H3/t17-,18-/m0/s1
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1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403782
PNG
(CHEMBL268973)
Show SMILES O=C1N(CCCCN2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C20H24N2O/c23-20-17-10-6-8-16-9-7-11-18(19(16)17)22(20)15-5-4-14-21-12-2-1-3-13-21/h6-11H,1-5,12-15H2
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403767
PNG
(CHEMBL12535)
Show SMILES CN1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C19H25N3O2S/c1-20-12-14-21(15-13-20)10-2-3-11-22-17-8-4-6-16-7-5-9-18(19(16)17)25(22,23)24/h4-9H,2-3,10-15H2,1H3
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403785
PNG
(CHEMBL12868)
Show SMILES CC1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C20H26N2O2S/c1-16-10-14-21(15-11-16)12-2-3-13-22-18-8-4-6-17-7-5-9-19(20(17)18)25(22,23)24/h4-9,16H,2-3,10-15H2,1H3
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403786
PNG
(CHEMBL273385)
Show SMILES CN1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C20H25N3O/c1-21-12-14-22(15-13-21)10-2-3-11-23-18-9-5-7-16-6-4-8-17(19(16)18)20(23)24/h4-9H,2-3,10-15H2,1H3
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50403783
PNG
(CHEMBL273890)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)C1CCCCC1)c23
Show InChI InChI=1S/C25H37N3O/c29-24-25(14-7-9-20-8-6-12-22(26-24)23(20)25)13-4-5-15-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h6,8,12,21H,1-5,7,9-11,13-19H2,(H,26,29)
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1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor in HEK 293 cells


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50403776
PNG
(CHEMBL275333)
Show SMILES O=S1(=O)N(CCCCN2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C19H24N2O2S/c22-24(23)18-11-7-9-16-8-6-10-17(19(16)18)21(24)15-5-4-14-20-12-2-1-3-13-20/h6-11H,1-5,12-15H2
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<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 7 receptor using [3H]-5-CT in rat hypothalamus membranes


Bioorg Med Chem Lett 10: 1097-100 (2000)


Article DOI: 10.1016/s0960-894x(00)00166-9
BindingDB Entry DOI: 10.7270/Q2JS9RNJ
More data for this
Ligand-Target Pair