BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50043468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50441530
PNG
(CHEMBL2436938)
Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2c3ccccc3sc2c1O
Show InChI InChI=1S/C15H9N3O4S/c16-5-8-11-7-3-1-2-4-9(7)23-14(11)13(21)12(18-8)15(22)17-6-10(19)20/h1-4,21H,6H2,(H,17,22)(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50441531
PNG
(CHEMBL2436937)
Show SMILES OC(=O)CNC(=O)c1nc(Cl)c2c3ccccc3sc2c1O
Show InChI InChI=1S/C14H9ClN2O4S/c15-13-9-6-3-1-2-4-7(6)22-12(9)11(20)10(17-13)14(21)16-5-8(18)19/h1-4,20H,5H2,(H,16,21)(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50441532
PNG
(CHEMBL2436936)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2sc3ccccc3c12
Show InChI InChI=1S/C15H12N2O4S/c1-7-11-8-4-2-3-5-9(8)22-14(11)13(20)12(17-7)15(21)16-6-10(18)19/h2-5,20H,6H2,1H3,(H,16,21)(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50193145
PNG
(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)
Show SMILES OC(=O)CNC(=O)c1nc(Cl)c2ccccc2c1O
Show InChI InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50441533
PNG
(CHEMBL2436935)
Show SMILES OC(=O)CNC(=O)c1ncc2c3ccccc3sc2c1O
Show InChI InChI=1S/C14H10N2O4S/c17-10(18)6-16-14(20)11-12(19)13-8(5-15-11)7-3-1-2-4-9(7)21-13/h1-5,19H,6H2,(H,16,20)(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50441534
PNG
(CHEMBL2436934)
Show SMILES OC(=O)CNC(=O)c1ncc2c3ccccc3oc2c1O
Show InChI InChI=1S/C14H10N2O5/c17-10(18)6-16-14(20)11-12(19)13-8(5-15-11)7-3-1-2-4-9(7)21-13/h1-5,19H,6H2,(H,16,20)(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.55E+4n/an/an/an/an/an/a



Sungkyunkwan University

Curated by ChEMBL


Assay Description
Inhibition of PHD2 (unknown origin) after 30 mins by fluorescence polarization assay


Bioorg Med Chem Lett 23: 5953-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.067
BindingDB Entry DOI: 10.7270/Q2XK8H1J
More data for this
Ligand-Target Pair