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Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 50043778   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 5


(Homo sapiens)
BDBM50446220
PNG
(CHEMBL3109164)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H29NO7/c28-25(20-12-7-13-27(20)26(29)33-15-19-10-5-2-6-11-19)34-22-17-32-23-21(16-31-24(22)23)30-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2/t20-,21-,22-,23-,24-/m1/s1
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300n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446221
PNG
(CHEMBL3109163)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C35H38N2O8/c38-33(28-17-10-18-37(28)35(40)44-21-26-15-8-3-9-16-26)36-27(19-24-11-4-1-5-12-24)34(39)45-30-23-43-31-29(22-42-32(30)31)41-20-25-13-6-2-7-14-25/h1-9,11-16,27-32H,10,17-23H2,(H,36,38)/t27-,28-,29+,30+,31+,32+/m0/s1
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400n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446218
PNG
(CHEMBL3109166)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35NO9/c1-29(2,3)39-28(33)30-21(14-24(31)35-16-20-12-8-5-9-13-20)27(32)38-23-18-37-25-22(17-36-26(23)25)34-15-19-10-6-4-7-11-19/h4-13,21-23,25-26H,14-18H2,1-3H3,(H,30,33)/t21-,22+,23+,25+,26+/m0/s1
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600n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446219
PNG
(CHEMBL3109165)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H42N2O9/c1-32(2,3)43-31(37)34-24(16-10-11-17-33-30(36)41-19-23-14-8-5-9-15-23)29(35)42-26-21-40-27-25(20-39-28(26)27)38-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,36)(H,34,37)/t24-,25+,26+,27+,28+/m0/s1
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700n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446218
PNG
(CHEMBL3109166)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35NO9/c1-29(2,3)39-28(33)30-21(14-24(31)35-16-20-12-8-5-9-13-20)27(32)38-23-18-37-25-22(17-36-26(23)25)34-15-19-10-6-4-7-11-19/h4-13,21-23,25-26H,14-18H2,1-3H3,(H,30,33)/t21-,22+,23+,25+,26+/m0/s1
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1.30E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446219
PNG
(CHEMBL3109165)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H42N2O9/c1-32(2,3)43-31(37)34-24(16-10-11-17-33-30(36)41-19-23-14-8-5-9-15-23)29(35)42-26-21-40-27-25(20-39-28(26)27)38-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,36)(H,34,37)/t24-,25+,26+,27+,28+/m0/s1
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1.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446228
PNG
(CHEMBL3109061)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCCN=C(NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C40H49N5O10/c1-40(2,3)55-39(49)43-30(35(46)42-31-25-51-34-32(26-52-33(31)34)50-22-27-14-7-4-8-15-27)20-13-21-41-36(44-37(47)53-23-28-16-9-5-10-17-28)45-38(48)54-24-29-18-11-6-12-19-29/h4-12,14-19,30-34H,13,20-26H2,1-3H3,(H,42,46)(H,43,49)(H2,41,44,45,47,48)/t30-,31+,32-,33-,34-/m1/s1
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1.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446227
PNG
(CHEMBL3109056)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccs1
Show InChI InChI=1S/C27H26N2O5S/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-35-20)27(31)29-22-16-33-25-23(17-34-24(22)25)32-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23+,24+,25+/m0/s1
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1.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446220
PNG
(CHEMBL3109164)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H29NO7/c28-25(20-12-7-13-27(20)26(29)33-15-19-10-5-2-6-11-19)34-22-17-32-23-21(16-31-24(22)23)30-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2/t20-,21-,22-,23-,24-/m1/s1
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1.90E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446224
PNG
(CHEMBL3109160)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H35NO8/c1-28(2,3)37-27(31)29-21(16-32-14-19-10-6-4-7-11-19)26(30)36-23-18-35-24-22(17-34-25(23)24)33-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)/t21-,22-,23-,24-,25-/m1/s1
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2.30E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446211
PNG
(CHEMBL3109058)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H43N3O8/c1-32(2,3)43-31(38)35-24(16-10-11-17-33-30(37)42-19-23-14-8-5-9-15-23)29(36)34-25-20-40-28-26(21-41-27(25)28)39-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,37)(H,34,36)(H,35,38)/t24-,25-,26+,27+,28+/m0/s1
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2.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446224
PNG
(CHEMBL3109160)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H35NO8/c1-28(2,3)37-27(31)29-21(16-32-14-19-10-6-4-7-11-19)26(30)36-23-18-35-24-22(17-34-25(23)24)33-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)/t21-,22-,23-,24-,25-/m1/s1
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2.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446228
PNG
(CHEMBL3109061)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCCN=C(NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C40H49N5O10/c1-40(2,3)55-39(49)43-30(35(46)42-31-25-51-34-32(26-52-33(31)34)50-22-27-14-7-4-8-15-27)20-13-21-41-36(44-37(47)53-23-28-16-9-5-10-17-28)45-38(48)54-24-29-18-11-6-12-19-29/h4-12,14-19,30-34H,13,20-26H2,1-3H3,(H,42,46)(H,43,49)(H2,41,44,45,47,48)/t30-,31+,32-,33-,34-/m1/s1
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2.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446221
PNG
(CHEMBL3109163)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C35H38N2O8/c38-33(28-17-10-18-37(28)35(40)44-21-26-15-8-3-9-16-26)36-27(19-24-11-4-1-5-12-24)34(39)45-30-23-43-31-29(22-42-32(30)31)41-20-25-13-6-2-7-14-25/h1-9,11-16,27-32H,10,17-23H2,(H,36,38)/t27-,28-,29+,30+,31+,32+/m0/s1
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2.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446211
PNG
(CHEMBL3109058)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H43N3O8/c1-32(2,3)43-31(38)35-24(16-10-11-17-33-30(37)42-19-23-14-8-5-9-15-23)29(36)34-25-20-40-28-26(21-41-27(25)28)39-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,37)(H,34,36)(H,35,38)/t24-,25-,26+,27+,28+/m0/s1
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2.90E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446229
PNG
(CHEMBL3109060)
Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C35H41N3O7/c1-23(2)30(38-35(41)45-20-26-16-10-5-11-17-26)34(40)36-27(18-24-12-6-3-7-13-24)33(39)37-28-21-43-32-29(22-44-31(28)32)42-19-25-14-8-4-9-15-25/h3-17,23,27-32H,18-22H2,1-2H3,(H,36,40)(H,37,39)(H,38,41)/t27-,28+,29-,30+,31-,32-/m1/s1
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3.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446229
PNG
(CHEMBL3109060)
Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C35H41N3O7/c1-23(2)30(38-35(41)45-20-26-16-10-5-11-17-26)34(40)36-27(18-24-12-6-3-7-13-24)33(39)37-28-21-43-32-29(22-44-31(28)32)42-19-25-14-8-4-9-15-25/h3-17,23,27-32H,18-22H2,1-2H3,(H,36,40)(H,37,39)(H,38,41)/t27-,28+,29-,30+,31-,32-/m1/s1
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3.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446230
PNG
(CHEMBL3109059)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cnc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2CO[C@@H]3[C@@H](CO[C@H]23)OCc2ccccc2)c1
Show InChI InChI=1S/C31H38N4O8S/c1-20-10-12-23(13-11-20)44(38,39)35-15-22(32-19-35)14-24(34-30(37)43-31(2,3)4)29(36)33-25-17-41-28-26(18-42-27(25)28)40-16-21-8-6-5-7-9-21/h5-13,15,19,24-28H,14,16-18H2,1-4H3,(H,33,36)(H,34,37)/t24-,25-,26+,27+,28+/m0/s1
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4.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446212
PNG
(CHEMBL3109057)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H30N2O6/c29-25(21-12-7-13-28(21)26(30)34-15-19-10-5-2-6-11-19)27-20-16-32-24-22(17-33-23(20)24)31-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2,(H,27,29)/t20-,21+,22+,23+,24+/m0/s1
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1.51E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446226
PNG
(CHEMBL3109158)
Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H31NO7/c1-23(2,3)31-22(26)24-11-7-10-16(24)21(25)30-18-14-29-19-17(13-28-20(18)19)27-12-15-8-5-4-6-9-15/h4-6,8-9,16-20H,7,10-14H2,1-3H3/t16-,17+,18+,19+,20+/m0/s1
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1.56E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446223
PNG
(CHEMBL3109161)
Show SMILES CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H33NO7S/c1-23(2,3)31-22(26)24-16(10-11-32-4)21(25)30-18-14-29-19-17(13-28-20(18)19)27-12-15-8-6-5-7-9-15/h5-9,16-20H,10-14H2,1-4H3,(H,24,26)/t16-,17+,18+,19+,20+/m0/s1
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1.84E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446215
PNG
(CHEMBL3109169)
Show SMILES CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H34N2O6S/c1-23(2,3)31-22(27)25-16(10-11-32-4)21(26)24-17-13-29-20-18(14-30-19(17)20)28-12-15-8-6-5-7-9-15/h5-9,16-20H,10-14H2,1-4H3,(H,24,26)(H,25,27)/t16-,17-,18+,19+,20+/m0/s1
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2.66E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446214
PNG
(CHEMBL3109170)
Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35N3O6/c1-29(2,3)38-28(34)32-22(13-19-14-30-21-12-8-7-11-20(19)21)27(33)31-23-16-36-26-24(17-37-25(23)26)35-15-18-9-5-4-6-10-18/h4-12,14,22-26,30H,13,15-17H2,1-3H3,(H,31,33)(H,32,34)/t22-,23+,24-,25-,26-/m1/s1
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2.82E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446227
PNG
(CHEMBL3109056)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccs1
Show InChI InChI=1S/C27H26N2O5S/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-35-20)27(31)29-22-16-33-25-23(17-34-24(22)25)32-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23+,24+,25+/m0/s1
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7.07E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446220
PNG
(CHEMBL3109164)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H29NO7/c28-25(20-12-7-13-27(20)26(29)33-15-19-10-5-2-6-11-19)34-22-17-32-23-21(16-31-24(22)23)30-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2/t20-,21-,22-,23-,24-/m1/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446221
PNG
(CHEMBL3109163)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C35H38N2O8/c38-33(28-17-10-18-37(28)35(40)44-21-26-15-8-3-9-16-26)36-27(19-24-11-4-1-5-12-24)34(39)45-30-23-43-31-29(22-42-32(30)31)41-20-25-13-6-2-7-14-25/h1-9,11-16,27-32H,10,17-23H2,(H,36,38)/t27-,28-,29+,30+,31+,32+/m0/s1
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n/an/a 3.90E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446218
PNG
(CHEMBL3109166)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35NO9/c1-29(2,3)39-28(33)30-21(14-24(31)35-16-20-12-8-5-9-13-20)27(32)38-23-18-37-25-22(17-36-26(23)25)34-15-19-10-6-4-7-11-19/h4-13,21-23,25-26H,14-18H2,1-3H3,(H,30,33)/t21-,22+,23+,25+,26+/m0/s1
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n/an/a 4.70E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446219
PNG
(CHEMBL3109165)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H42N2O9/c1-32(2,3)43-31(37)34-24(16-10-11-17-33-30(36)41-19-23-14-8-5-9-15-23)29(35)42-26-21-40-27-25(20-39-28(26)27)38-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,36)(H,34,37)/t24-,25+,26+,27+,28+/m0/s1
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n/an/a 9.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446218
PNG
(CHEMBL3109166)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35NO9/c1-29(2,3)39-28(33)30-21(14-24(31)35-16-20-12-8-5-9-13-20)27(32)38-23-18-37-25-22(17-36-26(23)25)34-15-19-10-6-4-7-11-19/h4-13,21-23,25-26H,14-18H2,1-3H3,(H,30,33)/t21-,22+,23+,25+,26+/m0/s1
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n/an/a 1.02E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446228
PNG
(CHEMBL3109061)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCCN=C(NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C40H49N5O10/c1-40(2,3)55-39(49)43-30(35(46)42-31-25-51-34-32(26-52-33(31)34)50-22-27-14-7-4-8-15-27)20-13-21-41-36(44-37(47)53-23-28-16-9-5-10-17-28)45-38(48)54-24-29-18-11-6-12-19-29/h4-12,14-19,30-34H,13,20-26H2,1-3H3,(H,42,46)(H,43,49)(H2,41,44,45,47,48)/t30-,31+,32-,33-,34-/m1/s1
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n/an/a 1.18E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446227
PNG
(CHEMBL3109056)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccs1
Show InChI InChI=1S/C27H26N2O5S/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-35-20)27(31)29-22-16-33-25-23(17-34-24(22)25)32-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23+,24+,25+/m0/s1
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n/an/a 1.33E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446211
PNG
(CHEMBL3109058)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H43N3O8/c1-32(2,3)43-31(38)35-24(16-10-11-17-33-30(37)42-19-23-14-8-5-9-15-23)29(36)34-25-20-40-28-26(21-41-27(25)28)39-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,37)(H,34,36)(H,35,38)/t24-,25-,26+,27+,28+/m0/s1
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n/an/a 1.33E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446219
PNG
(CHEMBL3109165)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H42N2O9/c1-32(2,3)43-31(37)34-24(16-10-11-17-33-30(36)41-19-23-14-8-5-9-15-23)29(35)42-26-21-40-27-25(20-39-28(26)27)38-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,36)(H,34,37)/t24-,25+,26+,27+,28+/m0/s1
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n/an/a 1.37E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446224
PNG
(CHEMBL3109160)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H35NO8/c1-28(2,3)37-27(31)29-21(16-32-14-19-10-6-4-7-11-19)26(30)36-23-18-35-24-22(17-34-25(23)24)33-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)/t21-,22-,23-,24-,25-/m1/s1
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n/an/a 1.55E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446224
PNG
(CHEMBL3109160)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H35NO8/c1-28(2,3)37-27(31)29-21(16-32-14-19-10-6-4-7-11-19)26(30)36-23-18-35-24-22(17-34-25(23)24)33-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)/t21-,22-,23-,24-,25-/m1/s1
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n/an/a 1.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446220
PNG
(CHEMBL3109164)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H29NO7/c28-25(20-12-7-13-27(20)26(29)33-15-19-10-5-2-6-11-19)34-22-17-32-23-21(16-31-24(22)23)30-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2/t20-,21-,22-,23-,24-/m1/s1
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n/an/a 1.66E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446228
PNG
(CHEMBL3109061)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCCN=C(NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C40H49N5O10/c1-40(2,3)55-39(49)43-30(35(46)42-31-25-51-34-32(26-52-33(31)34)50-22-27-14-7-4-8-15-27)20-13-21-41-36(44-37(47)53-23-28-16-9-5-10-17-28)45-38(48)54-24-29-18-11-6-12-19-29/h4-12,14-19,30-34H,13,20-26H2,1-3H3,(H,42,46)(H,43,49)(H2,41,44,45,47,48)/t30-,31+,32-,33-,34-/m1/s1
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n/an/a 1.69E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446221
PNG
(CHEMBL3109163)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C35H38N2O8/c38-33(28-17-10-18-37(28)35(40)44-21-26-15-8-3-9-16-26)36-27(19-24-11-4-1-5-12-24)34(39)45-30-23-43-31-29(22-42-32(30)31)41-20-25-13-6-2-7-14-25/h1-9,11-16,27-32H,10,17-23H2,(H,36,38)/t27-,28-,29+,30+,31+,32+/m0/s1
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n/an/a 1.96E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446229
PNG
(CHEMBL3109060)
Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C35H41N3O7/c1-23(2)30(38-35(41)45-20-26-16-10-5-11-17-26)34(40)36-27(18-24-12-6-3-7-13-24)33(39)37-28-21-43-32-29(22-44-31(28)32)42-19-25-14-8-4-9-15-25/h3-17,23,27-32H,18-22H2,1-2H3,(H,36,40)(H,37,39)(H,38,41)/t27-,28+,29-,30+,31-,32-/m1/s1
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n/an/a 2.17E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446212
PNG
(CHEMBL3109057)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H30N2O6/c29-25(21-12-7-13-28(21)26(30)34-15-19-10-5-2-6-11-19)27-20-16-32-24-22(17-33-23(20)24)31-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2,(H,27,29)/t20-,21+,22+,23+,24+/m0/s1
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n/an/a 2.36E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446211
PNG
(CHEMBL3109058)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H43N3O8/c1-32(2,3)43-31(38)35-24(16-10-11-17-33-30(37)42-19-23-14-8-5-9-15-23)29(36)34-25-20-40-28-26(21-41-27(25)28)39-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,37)(H,34,36)(H,35,38)/t24-,25-,26+,27+,28+/m0/s1
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n/an/a 2.36E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446226
PNG
(CHEMBL3109158)
Show SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H31NO7/c1-23(2,3)31-22(26)24-11-7-10-16(24)21(25)30-18-14-29-19-17(13-28-20(18)19)27-12-15-8-5-4-6-9-15/h4-6,8-9,16-20H,7,10-14H2,1-3H3/t16-,17+,18+,19+,20+/m0/s1
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n/an/a 2.44E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446230
PNG
(CHEMBL3109059)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cnc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2CO[C@@H]3[C@@H](CO[C@H]23)OCc2ccccc2)c1
Show InChI InChI=1S/C31H38N4O8S/c1-20-10-12-23(13-11-20)44(38,39)35-15-22(32-19-35)14-24(34-30(37)43-31(2,3)4)29(36)33-25-17-41-28-26(18-42-27(25)28)40-16-21-8-6-5-7-9-21/h5-13,15,19,24-28H,14,16-18H2,1-4H3,(H,33,36)(H,34,37)/t24-,25-,26+,27+,28+/m0/s1
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n/an/a 2.78E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446223
PNG
(CHEMBL3109161)
Show SMILES CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H33NO7S/c1-23(2,3)31-22(26)24-16(10-11-32-4)21(25)30-18-14-29-19-17(13-28-20(18)19)27-12-15-8-6-5-7-9-15/h5-9,16-20H,10-14H2,1-4H3,(H,24,26)/t16-,17+,18+,19+,20+/m0/s1
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n/an/a 2.87E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446215
PNG
(CHEMBL3109169)
Show SMILES CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H34N2O6S/c1-23(2,3)31-22(27)25-16(10-11-32-4)21(26)24-17-13-29-20-18(14-30-19(17)20)28-12-15-8-6-5-7-9-15/h5-9,16-20H,10-14H2,1-4H3,(H,24,26)(H,25,27)/t16-,17-,18+,19+,20+/m0/s1
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n/an/a 3.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446214
PNG
(CHEMBL3109170)
Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35N3O6/c1-29(2,3)38-28(34)32-22(13-19-14-30-21-12-8-7-11-20(19)21)27(33)31-23-16-36-26-24(17-37-25(23)26)35-15-18-9-5-4-6-10-18/h4-12,14,22-26,30H,13,15-17H2,1-3H3,(H,31,33)(H,32,34)/t22-,23+,24-,25-,26-/m1/s1
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n/an/a 3.92E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446216
PNG
(CHEMBL3109168)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H36N2O7/c1-28(2,3)37-27(32)30-22(16-33-14-19-10-6-4-7-11-19)26(31)29-21-17-35-25-23(18-36-24(21)25)34-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)(H,30,32)/t21-,22+,23+,24+,25+/m0/s1
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n/an/a 5.39E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446229
PNG
(CHEMBL3109060)
Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C35H41N3O7/c1-23(2)30(38-35(41)45-20-26-16-10-5-11-17-26)34(40)36-27(18-24-12-6-3-7-13-24)33(39)37-28-21-43-32-29(22-44-31(28)32)42-19-25-14-8-4-9-15-25/h3-17,23,27-32H,18-22H2,1-2H3,(H,36,40)(H,37,39)(H,38,41)/t27-,28+,29-,30+,31-,32-/m1/s1
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n/an/a 5.66E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446222
PNG
(CHEMBL3109162)
Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H34N2O7/c1-29(2,3)38-28(33)31-22(13-19-14-30-21-12-8-7-11-20(19)21)27(32)37-24-17-36-25-23(16-35-26(24)25)34-15-18-9-5-4-6-10-18/h4-12,14,22-26,30H,13,15-17H2,1-3H3,(H,31,33)/t22-,23-,24-,25-,26-/m1/s1
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n/an/a 5.92E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50446216
PNG
(CHEMBL3109168)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H36N2O7/c1-28(2,3)37-27(32)30-22(16-33-14-19-10-6-4-7-11-19)26(31)29-21-17-35-25-23(18-36-24(21)25)34-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)(H,30,32)/t21-,22+,23+,24+,25+/m0/s1
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n/an/a 8.45E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...


Citation and Details

Article DOI: 10.1021/ml4003698
BindingDB Entry DOI: 10.7270/Q2W37XSV
More data for this
Ligand-Target Pair
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