Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ec50 for monomerid = 19857
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)
Affinity DataIC50:  9.5nM EC50:  41nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)
Affinity DataIC50:  4.20E+3nM EC50:  2.90E+3nMpH: 6.0 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)
Affinity DataIC50:  8.50E+3nM EC50:  6.70E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)
Affinity DataIC50:  2.40E+4nM EC50: >1.00E+4nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19857(N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)
Affinity DataIC50:  2.70E+4nM EC50: >1.00E+4nMpH: 6.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed