TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Mayo Clinic And Foundation
Curated by ChEMBL
Mayo Clinic And Foundation
Curated by ChEMBL
Affinity DataEC50: 0.00900nMAssay Description:Ability to stimulate intracellular calcium response was determined using CCK receptor-bearing chinese hamster ovary cell lineMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0437nMAssay Description:Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0930nMAssay Description:Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.501nMAssay Description:Agonist activity at human CCK2R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.630nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.630nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Mayo Clinic And Foundation
Curated by ChEMBL
Mayo Clinic And Foundation
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nM EC50: 27nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKd: 1.90nM EC50: 28nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair