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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 228518   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM228518
PNG
(US9340542, 8)
Show SMILES Oc1ccc2C[C@]34CC[C@@]5(C[C@]3(CCN(CC3CC3)C4)c2c1)NC(=O)NC5=O
Show InChI InChI=1S/C22H27N3O3/c26-16-4-3-15-10-20-5-6-22(18(27)23-19(28)24-22)12-21(20,17(15)9-16)7-8-25(13-20)11-14-1-2-14/h3-4,9,14,26H,1-2,5-8,10-13H2,(H2,23,24,27,28)/t20-,21+,22-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 384n/an/a7.4n/a



Purdue Pharma LP

US Patent


Assay Description
Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding fin...


US Patent US9340542 (2016)


BindingDB Entry DOI: 10.7270/Q2PZ57P7
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM228518
PNG
(US9340542, 8)
Show SMILES Oc1ccc2C[C@]34CC[C@@]5(C[C@]3(CCN(CC3CC3)C4)c2c1)NC(=O)NC5=O
Show InChI InChI=1S/C22H27N3O3/c26-16-4-3-15-10-20-5-6-22(18(27)23-19(28)24-22)12-21(20,17(15)9-16)7-8-25(13-20)11-14-1-2-14/h3-4,9,14,26H,1-2,5-8,10-13H2,(H2,23,24,27,28)/t20-,21+,22-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 414n/an/a7.4n/a



Purdue Pharma LP

US Patent


Assay Description
[35S]GTPγS functional assays were conducted using freshly thawed p-receptor membranes prepared in-house from a cell line expressing recombinant ...


US Patent US9340542 (2016)


BindingDB Entry DOI: 10.7270/Q2PZ57P7
More data for this
Ligand-Target Pair