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Found 3 of ic50 for monomerid = 11245
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Purdue University

Curated by ChEMBL
LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory concentration required for antiviral activity against SARS-CoV 3CLpro proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50:  8.70E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed