Compile Data Set for Download or QSAR
maximum 50k data
Found 2 of ic50 for monomerid = 20182
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed