Affinity DataIC50: 0.330nMAssay Description:Displacement of radioligand from Estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory concentration against [3H]-17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 9nM EC50: 0.0200nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 12nM EC50: 0.0600nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by ChEMBL
Japanese Foundation For Cancer Research
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation For Cancer Research
Curated by ChEMBL
Japanese Foundation For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Displacement of [3H]-estradiol from human recombinant ERbeta expressed in Sf21 cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Displacement of [3H]-estradiol from human recombinant ERalpha expressed in Sf21 cells after 2 hrsMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of rabbit microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.46E+4nMAssay Description:Antagonist activity at full length human PXR transfected in human HepG2 cells assessed as reduction in rifaximin-induced receptor transactivation aft...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human GalE by HPAEC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+4nMAssay Description:CA activity was measured by the Maren method which is based on determination of the time required for the pH to decrease from 10.0 to 7.4 due to CO2 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMAssay Description:CA activity was measured by the Maren method which is based on determination of the time required for the pH to decrease from 10.0 to 7.4 due to CO2 ...More data for this Ligand-Target Pair