Affinity DataIC50: 19nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:Inhibition of ATP-ase activity in human colon tumor cell line (HCT116)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
University Of Texas Southwestern Medical Center
Affinity DataIC50: 7.78E+4nMpH: 7.5 T: 2°CAssay Description:To determine the IC50 for PDK inhibitors, a mixture containing 0.05-0.2 μM PDK, 6μM E1, with or without 0.5 μM of the PDC core E2/E3BP...More data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Vernalis (R&D)
Curated by ChEMBL
Vernalis (R&D)
Curated by ChEMBL
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of SUMO-tagged PDHK1 (unknown origin) in presence of [gamma-32P]ATP after 30 mins by SDS-PAGE based phosphor imaging methodMore data for this Ligand-Target Pair