BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 274685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I delta/epsilon


(Homo sapiens (Human))
BDBM274685
PNG
(N-(6-(1-(2-tert-butoxyethyl)-4-(4- fluorophenyl)-1...)
Show SMILES CC(C)(C)OCCn1cnc(c1-c1ccc2nc(NC(=O)c3ccnc(F)c3)cn2n1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H25F2N7O2/c1-27(2,3)38-13-12-35-16-31-24(17-4-6-19(28)7-5-17)25(35)20-8-9-23-32-22(15-36(23)34-20)33-26(37)18-10-11-30-21(29)14-18/h4-11,14-16H,12-13H2,1-3H3,(H,33,37)
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.403n/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...


US Patent US9556179 (2017)


BindingDB Entry DOI: 10.7270/Q2G73GR5
More data for this
Ligand-Target Pair
Casein kinase I Epsilon


(Homo sapiens (Human))
BDBM274685
PNG
(N-(6-(1-(2-tert-butoxyethyl)-4-(4- fluorophenyl)-1...)
Show SMILES CC(C)(C)OCCn1cnc(c1-c1ccc2nc(NC(=O)c3ccnc(F)c3)cn2n1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H25F2N7O2/c1-27(2,3)38-13-12-35-16-31-24(17-4-6-19(28)7-5-17)25(35)20-8-9-23-32-22(15-36(23)34-20)33-26(37)18-10-11-30-21(29)14-18/h4-11,14-16H,12-13H2,1-3H3,(H,33,37)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.53n/an/an/an/a7.425



Bristol-Myers Squibb Co.

US Patent


Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...


US Patent US9556179 (2017)


BindingDB Entry DOI: 10.7270/Q2G73GR5
More data for this
Ligand-Target Pair