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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 276752   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM276752
PNG
(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1
Show InChI InChI=1S/C22H23N5O5S/c1-3-31-18-5-4-7-24-21(18)32-17-9-15(10-23-13-17)19-25-11-16(12-26-19)20(28)27-22(2)6-8-33(29,30)14-22/h4-5,7,9-13H,3,6,8,14H2,1-2H3,(H,27,28)
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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...


US Patent US11065249 (2021)

More data for this
Ligand-Target Pair
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM276752
PNG
(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1
Show InChI InChI=1S/C22H23N5O5S/c1-3-31-18-5-4-7-24-21(18)32-17-9-15(10-23-13-17)19-25-11-16(12-26-19)20(28)27-22(2)6-8-33(29,30)14-22/h4-5,7,9-13H,3,6,8,14H2,1-2H3,(H,27,28)
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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13.5n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...


US Patent US11034678 (2021)

More data for this
Ligand-Target Pair
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM276752
PNG
(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Show SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1
Show InChI InChI=1S/C22H23N5O5S/c1-3-31-18-5-4-7-24-21(18)32-17-9-15(10-23-13-17)19-25-11-16(12-26-19)20(28)27-22(2)6-8-33(29,30)14-22/h4-5,7,9-13H,3,6,8,14H2,1-2H3,(H,27,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 13.5n/an/an/an/a7.425



Pfizer Inc

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...


US Patent US10071992 (2018)


BindingDB Entry DOI: 10.7270/Q2RJ4MHN
More data for this
Ligand-Target Pair