Compile Data Set for Download or QSAR
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Found 2 of ic50 for monomerid = 27888
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM27888(4-{[2-(4-chloro-1H-pyrazol-1-yl)ethyl]amino}-3-{6-...)
Affinity DataIC50:  34nMpH: 7.0 T: 2°CAssay Description:The IGF-1 receptor tyrosine kinase was assayed using the synthetic polymer poly(Glu/Tyr) as a phosphoacceptor substrate. Incorporated radioactivity w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM27888(4-{[2-(4-chloro-1H-pyrazol-1-yl)ethyl]amino}-3-{6-...)
Affinity DataIC50:  2.60E+4nMpH: 7.4 T: 2°CAssay Description:The inhibition of recombinant human CYP3A4 was measured as the ability to perform a dealkylation of 7-benzyloxy-4-trifluoromethylcoumarin (BFC). Befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed