Affinity DataIC50: 0.430nMAssay Description:In vitro inhibitory activity of the compound against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibitory concentration of the compound was determined in vitro and ex vivo for anti-AChE activity in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against acetylcholinesterase as a prodrug was demonstratedMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) using acetylcholine iodide as substrate preincubated for 15 mins prior to substrate addition by s...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:In vitro inhibitory concentration of the compound against butyrylcholinesterase (BuChE) obtained from rat plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibitory concentration was determined in in vitro for Butyrylcholinesterase in rat plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of AChE in Wistar rat brain homogenate using acetylthiocholine iodide as substrate after 0.5 hrs by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Universidad Nacional Del Sur
Curated by ChEMBL
Universidad Nacional Del Sur
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Pacific electric ray AChE using acetylthiocholine iodide as substrate after 60 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of BChE in horse serum using butyrylthiocholine iodide as substrate after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
National Chung-Hsing University
Curated by ChEMBL
National Chung-Hsing University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Compound was evaluated for its inhibitory concentration against Horse serum ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against acetylcholinesterase in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 19.0nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 27.9nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 27.9nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit hydrolytic activity of Acetylcholinesterase by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Acetylcholinesterase(AChE) from human RBCMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against Acetylcholinesterase in erythrocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human acetylcholinesterase using acetylcholine iodide as substrate preincubated for 30 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against Acetylcholinesterase in cortexMore data for this Ligand-Target Pair