TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase(GAR-TFase) against hog liverMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Ability to inhibit glycinamide ribonucleotide transformylase (GAR-Tfase) in vitro, using hog liver with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactorMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.40E+4nMAssay Description:In vitro inhibitory activity of the compound against MOLT-4 T-cell leukemia cell AICAR transformylaseMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Mus musculus)
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair