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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50007270   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007270
PNG
(CHEMBL101718 | Sodium; 6-(3,5-dichloro-biphenyl-2-...)
Show SMILES OC(COc1c(Cl)cc(Cl)cc1-c1ccccc1)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C18H18Cl2O5/c19-12-6-15(11-4-2-1-3-5-11)18(16(20)7-12)25-10-14(22)8-13(21)9-17(23)24/h1-7,13-14,21-22H,8-10H2,(H,23,24)/p-1/t13-,14?/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair