TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck
Curated by ChEMBL
H. Lundbeck
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Ability to inhibit binding of [3H]PRAZ to alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Ability to displace [3H]ketanserin (0.5 nM) from cerebral cortex of rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Ability to displace [3H]spiperone (0.5 nM) from corpus striatum of rat Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Ability to inhibit binding of [3H]-SPI to dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity towardst dopamine D2 receptor by displacement of [3H]-SPI radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Ability to displace [3H]-SCH- 23390 (0.2 nM) from corpus striatum of rat Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Binding affinity towards dopamine receptor D1 by displacement of [3H]-SCH- radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiroperidolMore data for this Ligand-Target Pair