TargetDNA polymerase catalytic subunit(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataIC50: <280nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 polymerase using PPT57 DNA/Cy5-labeled PPT24 as template/primer preincubated for 10 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase M184V mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation proximity ass...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K65R mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA/DNAM duplex primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA PPT primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase E89T mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Instituto De QuíMica MéDica (Csic)
Curated by ChEMBL
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair