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Found 6 of ic50 for monomerid = 50013698
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  5.99E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  5.99E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Homo sapiens (Human))
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013698(8-Phenyl-9H-purine-2,6-diamine | CHEMBL66077)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed