Compile Data Set for Download or QSAR
maximum 50k data
Found 75 of ic50 for monomerid = 50014846
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine brain tubulin polymerization (ITP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Tested for inhibition against tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tubulin polymerization(ITP)More data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Displacement of [3H]Colchicine from pig biotinylated tubulin after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Displacement of [3H]colchicine from biotinylated pig brain tubulin after 2 hrs by competitive scintillation proximity assayMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.26E+3nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on tubulinMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 mins in presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.50E+3nMAssay Description:The compound was evaluated in vitro for the mammalian brain tubulin polymerization using standard assay.More data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization incubated for 60 mins by fluorescence-based assayMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of tubulin polymerization using isolated calf brain at 26 degrees CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Csir-Indian Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Tested for 50 % inhibition of tubulin polymerization by turbidimetric assayMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 30 minsMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tubulin polymerization by a 40 uM solution of compound; compound showed inhibition >50% at 40 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of tubulin polymerization using isolated calf brain at 37 degrees CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of purified bovine brain tubulin polymerisation in the absence of microtubule-associated proteins.More data for this Ligand-Target Pair
In DepthDetails
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization extent after 20 mins by turbidimetricallyMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Compound was evaluated for in vitro inhibitory activity against polymerization of tubulin into microtubules isolated from bovine brain at 1 mg/mL tub...More data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysisMore data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  4.17E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of tubulin polymerization with preincubation for 15 minutes at 37 degree Centigrade prior to addition of the GTP required for polymerizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human PIM1 measured after 5 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 sec for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization measured every 30 secs for 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of pig brain tubulin polymerization measured every 1 min for 25 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrophotometeric analysisMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization by fluorescence based assayMore data for this Ligand-Target Pair
TargetTubulin beta chain(Homo sapiens)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  6.93E+3nMAssay Description:Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of pig brain tubulin polymerization in presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  7.85E+3nMAssay Description:Binding affinity to pig brain tubulin polymerization measured every 1 mins of 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetTubulin beta chain(Sus scrofa)
University Of Cologne

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of tubulin polymerization activity using homogenous bovine brain tubulin at 45 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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