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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50134195   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50134195
PNG
(CHEMBL3735433)
Show SMILES N[C@H]1C[C@H](CO[C@@H]1c1cc(F)ccc1F)N1Cc2[nH]nc(NS(=O)(=O)Cc3ccncc3)c2C1
Show InChI InChI=1S/C22H24F2N6O3S/c23-14-1-2-18(24)16(7-14)21-19(25)8-15(11-33-21)30-9-17-20(10-30)27-28-22(17)29-34(31,32)12-13-3-5-26-6-4-13/h1-7,15,19,21H,8-12,25H2,(H2,27,28,29)/t15-,19+,21-/m1/s1
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Similars

Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant human DPP4 expressed in Sf9 cells using Gly-Pro-AMC substrate after 30 mins by plate reader analysis


Bioorg Med Chem Lett 25: 5767-71 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.070
BindingDB Entry DOI: 10.7270/Q208675S
More data for this
Ligand-Target Pair