BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50257383   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50257383
PNG
(CHEMBL493723 | ethyl 4-methyl-2-(4-(methyl(3,4,5-t...)
Show SMILES CCOC(=O)c1sc(Nc2nc(cc(n2)N2CCN(C)CC2)N(C)Cc2cc(OC)c(OC)c(OC)c2)nc1C
Show InChI InChI=1S/C27H37N7O5S/c1-8-39-25(35)24-17(2)28-27(40-24)31-26-29-21(15-22(30-26)34-11-9-32(3)10-12-34)33(4)16-18-13-19(36-5)23(38-7)20(14-18)37-6/h13-15H,8-12,16H2,1-7H3,(H,28,29,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of PDE5


Bioorg Med Chem Lett 19: 1935-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.060
BindingDB Entry DOI: 10.7270/Q2TM7B02
More data for this
Ligand-Target Pair