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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50295553   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50295553
PNG
(4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridi...)
Show SMILES OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2
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Patents

US Patent
n/an/a 30n/an/an/an/an/an/a



EverBrilliant Pharma Pty Ltd

US Patent


Assay Description
FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...


US Patent US11273153 (2022)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase


(Toxoplasma gondii)
BDBM50295553
PNG
(4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridi...)
Show SMILES OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of Toxoplasma gondii recombinant MAPK1 expressed in Escherichia coli


Antimicrob Agents Chemother 51: 4324-8 (2007)


Article DOI: 10.1128/AAC.00680-07
BindingDB Entry DOI: 10.7270/Q2Q52QJG
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50295553
PNG
(4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridi...)
Show SMILES OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Tulane University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant p38alpha assessed as [gamma33P]ATP utilization by microplate scintillation counting


Antimicrob Agents Chemother 51: 4324-8 (2007)


Article DOI: 10.1128/AAC.00680-07
BindingDB Entry DOI: 10.7270/Q2Q52QJG
More data for this
Ligand-Target Pair