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Found 3 of ic50 for monomerid = 50461083
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)
Affinity DataIC50:  44nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)
Affinity DataIC50: <100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Nestle Skin Health

Curated by ChEMBL
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)
Affinity DataIC50: <100nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent